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The winner of the Mandeville-Newman regular season finale benefited from 14 free passes
Mandeville's errors and free passes are pivotal against Newman and offer valuable lessons for future playoff success in Division I nonselect.
Resources for Educators: Ways to Incorporate Outdoor Science Education | College of Education News
Five Tips for Incorporating Outdoor Science Lessons
School's in Session, Part 2
Mark resumes his history lesson on how Secrets of Strixhaven came to be.
Sustainability At ESMT Berlin: Bees & Business Lessons
Learn about sustainability at ESMT, from bee-friendly gardens & solar initiatives, to master's & MBA students’ consulting projects.
Sustainability At ESMT Berlin: Bees & Business Lessons
ESMT Berlin is a place to find both future business leaders and bees. A strange combination, perhaps, but one that encapsulates sustainability at ESMT. Here, faculty prepare students to become chang...
Lessons from the OIG: Common Billing Errors Texas Home Health Providers Need to Know | Insights
The Texas Health and Human Services Office of Inspector General (HHSC-OIG) quarterly report highlights common billing errors and compliance issues in home healthcare settings.
Dauphin Island Sea Lab hosts Discovery Day open house
The event offered hands-on science lessons and free aquarium admission for children.
James Dainard on ‘Million Dollar Zombie Flips’ Season 2, lessons learned
Season 2 of A&E’s Seattle-set “Million Dollar Zombie Flips” premieres April 11.
Breaking Down Barriers
Through the student-led Colby Community Health Program, students and shelter guests exchange health tips, snacks, and life lessons.
Team IMPACT CEO Krissie Kelleher understands the healing power of sports, teamwork and community
Krissie Kelleher used lessons from her lacrosse career to guide her daughter through surgeries and treatment for a spinal cord tumor. Witnessing how sports helped her daughter heal emotionally and physically inspired Kelleher to lead Team IMPACT, a national nonprofit connecting children facing serious illness with NCAA sports teams. Today, the organization partners with more than 400 schools and 1,100 teams to help kids build confidence, find community and experience hope through teamwork.
20 years after passing nation-leading health care law, Mass. braces for new challenges
A landmark health coverage law passed 20 years ago gave Massachusetts among the lowest uninsured rates in the country. It inspired the sweeping federal overhaul known as the Affordable Care Act. Now many are wondering whether that period of intense negotiations and compromise offers lessons for today's urgent health care challenges.
The Reverend Jesse Jackson’s Sporting Life
The way Jackson carried himself in the sports world offers lessons progressives would do well to remember and carry forward.
Bruising Bruins dominate South Carolina, win an NCAA national title
UCLA coach Clori Close built on lessons learned from John Wooden and steered the Bruins to a lopsided win over South Carolina to clinch a national title.
Trump’s Lesson From Risky Rescue: Threaten to Go Harder at Iran
In an expletive-laced social media post, the president said Iran should open the Strait of Hormuz or he would bomb bridges and power plants.
7 Science Lessons In The Stunning Astronaut’s Earth Photo
Our breakdown of 7 hidden science lessons in the stunning photo taken by an astronaut on the Artemis II mission.
Democrats rebounding without learning necessary lessons
“When we fight, we win!” That, reportedly, was the chant heard over and over again at the Colorado Democratic Assembly a week ago. It suggests that pugilism has been the piece missing from the Democratic toolkit. Perhaps it was just me, but I seem to recall Democrats exhibiting plenty of fight back in 2024. The […]
Teen sports betting raises concerns in schools — and a push for financial literacy
Schools are using financial literacy lessons to address teen sports betting, as educators warn of risks, losses and growing exposure.
How did Wisconsin politics shape the nation? Here's what I learned
Ahead of America's 250th birthday, reporter Hope Karnopp explored three political movements in Wisconsin that shaped history. They carry lessons for today.
Why Critical Minerals Have Become a Business Risk Story, Not Just a Mining Story
The broader lesson is that critical minerals are not only a mining story. They are also a supply chain story.
Pepperdine University Hosts Thomas Vozzo, Former CEO of Homeboy Industries, for a Lecture on Faith and Business
Pepperdine University’s Faith and Business Initiative hosted Thomas Vozzo, the former CEO and current senior advisor of Homeboy Industries, for a lecture on faith, service, and lessons learned as a C-suite executive in both the for-profit and nonprofit sectors.
Want to renew healthy eating habits? Greek monks have a spring playbook
Across Greece and in Orthodox communities around the world, a centuries-old Lenten fast offers a modern lesson in diet and discipline.
Clemson scientist wins Governor’s Award for expanding science access
BeakerBox provides middle school classrooms with ready-to-use, inquiry=based science lessons that meet state education standards.
Science fiction icon disappointed by cancellation of this spin-off series
At 95, the genre’s most famous captain is defending a spin-off he never watched. When some call it "woke," he counters with a history lesson that fans may not expect.
Doris Kearns Goodwin shares lessons for today's politics
Presidential historian Doris Kearns Goodwin spoke at Assumption University, sharing lessons from history for today's political landscape.
📚 The Inoculation Project 3/29/2026: Kindergarten Books, Art Meets Science
This week, we’re helping a kindergarten teacher�in San Bernardino add�some books to her classroom, and a rural Michigan science teacher slide a little art into her science lessons. �We hope that ...
How baseball imitates life: Authors share tips for sports parents
What do Derek Jeter, Yoshinobu Yamamoto and "Seinfeld" have in common? They provide examples of how baseball lessons can help our kids succeed.
Findings on Entrepreneurs’ Earnings and Key Lessons - Small Business & Entrepreneurship Council
by Raymond J. Keating – While many entrepreneurs go through some tough times – particularly as their businesses are being started and during the early years – on the income front, as a business develops and grows, the anticipation is that revenue and earnings will grow, and so will the income of the entrepreneurs that […]
Lewis Hamilton shares “full circle” moment after "unreal" samurai experience
Lewis Hamilton reflected on a “full circle” moment in Tokyo after taking a samurai lesson from Kill Bill fight choreographer Tetsuro Shimaguchi ahead of the Japanese Grand Prix
Hands-on science program brings STEM to life at Mass. school
The school's 5th graders enjoyed a special science lesson by Preeti Mostello, an educator with the nonprofit Traveling Science Workshops from the Discovery Museum in Acton.
Sports agent imparts life lessons at T.W. Lewis series
Leigh Steinberg recently documented his highs, lows and rebound as a renowned sports agent in a soon-to-be released book. He shared his life lessons as […]
Enhancing laboratory preparedness in Eastern Partnership countries to address respiratory health threats
Workshop under the EU-funded Health Resilience in the Eastern Partnership project aim to help countries turn lessons from the COVID-19 pandemic into practical actions for stronger, more resilient public health laboratories.
She taught backyard swim lessons. A single complaint shut them down.
Local governments should encourage home businesses instead of making them illegal.
World TB Day: Scaling workplace healthcare interventions
Four lessons from the End Workplace TB initiative could help other private sector-led campaign coalitions to scale their workplace healthcare programmes.
Lessons from China—Questrom Class Took BU Students on Memorable Business Trip
Over spring break, 25 Boston University students joined Professor, Greg Stoller to see what Chinese companies could teach them
UGA student turns mahjong passion into growing business: Marejong
University of Georgia student Mary Dalton Dowdy started her own business, Marejong, teaching mahjong lessons in Athens, Jefferson, Watkinsville and Wrens, Georgia. She found a unique market, becoming one of
STC HVACR student turns childhood lessons into vision for future business
Currently pursuing an associate degree in Heating, Ventilation, AC and Refrigeration (HVACR) at South Texas College, Cesar Bernal III said he was just 12 years old when he began watching his father turn determination and hard work into a small but thriving air-conditioning business in Weslaco.
Lessons from Binghamton led alumni award winner to public health
Clare Biging ’16 is an epidemiologist and public health advocate at the New York City Department of Health and Mental Hygiene.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Learning by serving: Rose fellows reflect on lessons from the field | Harvard T.H. Chan School of Public Health
The Rose Service Learning Fellowship funds community-engaged field projects around the globe.
Lesson about lichens spurs kids' curiosity
A rainy day led a science club leader to teach third-graders about lichens, sparking curiosity and learning.
What Business Leaders Can Learn From A Symphony Orchestra
How Montreal Symphony Orchestra leaders balance artistic excellence and business strategy, offering lessons in leadership, innovation and audience growth.
Health literacy: 5 key lessons for better global health
One in four people around the world have low health literacy. Tackling that challenge could improve lives and save billions in healthcare funding globally.
5 lessons from a weekend vibe coding class as a non-technical person
I joined a weekend vibe coding class and built apps in two mornings. As a non-technical builder, I learned five lessons.
Colorado Springs charter school drops creationism lesson
A complaint prompted the school to remove creationism from an eighth-grade science unit.
From game plans to lesson plans: How teachers are using sports to teach economics
A St. Cloud State professor made lesson plans teaching econ using real-world examples, like the Minnesota Lynx, Caitlin Clark and Taylor Swift's effect on NFL viewership.
From game plans to lesson plans: How teachers are using sports to teach economics
St. Cloud State professors are teaching econ using real-world examples, like the Minnesota Lynx, Caitlin Clark, and Taylor Swift's effect on NFL viewership.
The founder of $100M brand Late July and Nixie started selling $1 cookies at 12 and learned the snack trade from the founder of Cape Cod chips—her dad
Nicole Bernard Dawes, the founder of Late July and Nixie, got her start in business selling $1 cookies at local delis—the lessons she learned from the $500 summer hustle led to multimillion-dollar success.
The New CEO Of Acquisition.com: From Goldman To Building The ‘Disney Of Business’
Most Goldman Sachs bankers leave with a set of deal-structuring skills and a polished LinkedIn profile. Sharran Srivatsaa left with a lesson he learned at a closing dinner.
I Watched My Father's Million-Dollar Business Fail — Here's What It Taught Me About Business
My father's restaurant hit $1 million in revenue and still went bankrupt. I was 11, and those lessons shaped every company I've built since.
Science Lesson About Elephant Whiskers
There are about 1,000 tiny hairs on an elephant’s rugged trunk, all designed to help the animal feel, a new study found.
New training at NSU helps educators teach computer science
NATCHITOCHES, La. (KTAL/KMSS) – New training at Northwestern State University’s School of Education is helping teachers integrate computer science into their lesson plans. NSU’s School of Education pa...
Carolyn Hax: Mom tries to be a realist, but her kids see only a killjoy
Letter writer learned not to get her hopes up, but her kids receive that lesson as “sucking the joy out of everything.”
Get a STEM lesson right at your door with Girls thINC Outside the Box
Girls Inc. of Metro Denver offers special Girls & Science edition of it's thINC Outside the Box activity.
The dangerous lesson countries may take from the Iran war
Having a nuclear weapon has never looked more appealing.
How three Paralympians are passing on lessons from sports and life to the next generation
Three Team USA Paralympic athletes are mentoring young students and passing on lessons from the field of competition and beyond.
A Classroom takes flight with Zion Williamson–inspired science lessons
A NYC high school class uses NBA star Zion Williamson’s injuries, body data and career path to explore nutrition, psychology and kinesiology.
Veterans see Iraq, Afghanistan lessons for a US-Iran war
Veterans say the decadeslong wars in Iraq and Afghanistan hold key lessons for US military action in Iran.
Traveling with kids taught me flexibility and stress management
Traveling the world with my kids has made me a better, more flexible parent. Here are 6 lessons I now live by whether we're home or abroad.
Fifth grade science in Pre-K; Coppell ISD prepares its students for the future
Fifth graders build hands-on science lessons and share them with Pre-K students, from circuits and light to sound and thermal energy.
A Political Risk Guru’s Biggest Worry About the Iran War
Ian Bremmer thinks Trump learned some dangerously misguided lessons from Venezuela.
Commentary: IC does not adequately support club sports
The memories, lessons and love that softball has brought me have proven invaluable, and that is something worth protecting. This institution does not give us money and actively impedes on our ability to play and practice. Access to Kostrinsky Field, even for just one day across a semester, would be a game-changer.
An $800,000 mistake taught CEO lesson about leadership
The CEO of an AI startup says a major gaffe he made earlier in his career taught him what good bosses do when employees screw up.
Stout turns local flooding issue into science lesson
Stout Middle School, in collaboration with a team from the University of Michigan, has turned a local environmental issue into a set of lessons for sixth grade science students. Students in Ms....
Jesse Jackson’s lyrical swagger and political ‘juice’ resonates as students learn about his legacy
At King College Prep on Chicago’s South Side, high schoolers got a crash course about the civil rights leader after his death. Their takeaway? ‘That man was a boss.’
Albert Breer’s Takeaways: Heeding the Lessons of the Lions’ 2023 Draft Class
NFL scouting combine risers and fallers: LB/DL | DB/TE | QB/RB/WR | OL INDIANAPOLIS — The 2026 NFL combine, my 18th, is now in the books. And we have a little b
Nyla Johnson's connection one of Nolensville girls basketball best stories
Here's how Nolensville star Nyla Johnson has used lessons from her mother, a former Belmont basketball player, as she leads the Lady Knights this season.
Nyla Johnson's connection one of Nolensville girls basketball best stories
Here's how Nolensville star Nyla Johnson has used lessons from her mother, a former Belmont basketball player, as she leads the Lady Knights this season.
Why a Hawaii man chose to tackle his sports gambling addiction by offering free surf lessons to strangers
Spencer’s victory speech an object lesson in grace while Reform’s man rages
Matt Goodwin claimed cheating, Labour’s Gorton candidate quickly fled, Keir was tin-eared and Kemi brought the comedy
What economists got wrong about Trump’s tariffs
The 3 big lessons we’ve learned since “Liberation Day.”
Highland Towers’ $600,000 lesson in Tallahassee politics
Retirees caught between code ambiguity and construction lobbyists
Business Lessons From Curt Cignetti And The Indiana Hoosiers
Indiana acheived the impossible this year, winning a national championship for an historically losing team. Their story is ripe with leadership lessons for your business.
Great Oaks Elementary School's Hands-on Science Lesson
We took a trip up to Great Oaks Elementary School, where fourth-grade students explored the world o...
PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of Korea
IN THE SPOTLIGHT PRET for impact: Advancing pandemic preparedness in the Democratic People’s Republic of KoreaThe Democratic People’s Republic of Korea (DPR Korea) is making significant progress in strengthening pandemic preparedness, with dedicated support from the WHO South‑East Asia Regional Office (SEARO) and the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC).Aligned with the WHO Global Influenza Strategy and the Pandemic Influenza Preparedness (PIP) Framework Partnership Contribution High‑Level Implementation Plan III (2024–2030), the country is strengthening its capacity to prepare for and respond to influenza and other respiratory threats. In early 2025, a core team from the Ministry of Public Health of the Democratic People’s Republic of Korea (DPRK) participated in a two‑day virtual workshop, which included a mini‑simulation exercise. The workshop was organized by WHO SEARO in collaboration with the Preparedness and Resilience for Emerging Threats (PRET) Secretariat at WHO headquarters and the WHO Country Office for the DPRK. Read more A REGIONAL CONSULTATION GUIDES WHO SEARO IN DEVELOPING A ROADMAP FOR IMPLEMENTING THE PREPPAREDNESS AND RESILIENCE FOR EMERGING THREATS (PRET) INITIATIVE BASED RESPIRATORY PATHOGEN PANDEMIC PREPAREDNESSInfluenza and other respiratory pathogens with pandemic potential continue to pose major public health risks globally. To strengthen regional preparedness and response, Member States of the WHO South‑East Asia Region (SEAR) convened in Colombo, Sri Lanka, to review and provide input on the draft Roadmap and Action Framework for Broad Respiratory Pathogen Pandemic Planning (2026–2031). Supported through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) funds, the proposed roadmap aims to advance robust, integrated preparedness and response capacities for influenza and other respiratory threats across SEAR. This work is aligned with the Preparedness and Resilience for Emerging Threats (PRET) initiative and the SEAR Strategic Roadmap on Health Security and Health System Resilience for Emergencies Read moreSRI LANKA’S USE OF ANTIVIRALS TO REDUCE THE SEASONAL INFLUENZA BURDEN Sri Lanka is strengthening its influenza response by placing greater emphasis on rapid testing, timely treatment, and integration with maternal health services. With support from WHO, the country is building a stronger evidence base on the burden of influenza and the value of vaccination, advancing a holistic approach to protect vulnerable populations and enhance pandemic preparedness. To reduce hospitalizations and deaths from seasonal influenza, Sri Lanka is taking proactive steps to expand access to rapid diagnostic testing and ensure prompt initiation of treatment. National clinical guidelines recommend the use of oseltamivir for individuals at high risk of complications, helping prevent severe illness and shorten the duration of infection. This strategy not only saves lives but also supports local pharmaceutical production, contributing to a reliable supply of antivirals for both seasonal outbreaks and future pandemics.Read moreBHUTAN BOOSTS PANDEMIC INFLUENZA READINESS WITH PANDEMIC INFLUENZA PREPAREDNESS FRAMEWORK PARTNERSHIP CONTRIBUTION SUPPORTED TRAINING AND SIMULATIONSOriginally developed in 2012, the National Influenza Pandemic Preparedness and Response Plan (NIPPRP) has long served as Bhutan’s central framework for managing influenza threats. In 2024, the plan underwent a comprehensive update to reflect evolving global and regional guidance, lessons learned from the COVID‑19 pandemic, and new capacities developed under the PIP Framework. The revised NIPPRP is now more clearly aligned with Bhutan’s broader emergency and disaster risk management structures, ensuring a coordinated, whole‑of‑government approach to pandemic response. As part of efforts to strengthen national pandemic preparedness, Bhutan conducted three national‑level training sessions followed by simulation exercises on influenza pandemic preparedness and response at five sentinel hospitals between April and May 2025, with support from the PIP Partnership Contribution (PC). These activities brought together more than 140 health professionals and key partners from across the country, with a focus on operationalizing the updated NIPPRP and enhancing readiness at key frontline facilities. Read moreSTRENGTHENING INFLUENZA SURVEILLANCE: WHO BRINGS TOGETHER INFLUENZA EXPERTS FROM SOUTH-EAST ASIA AND WESTERN PACIFIC REGIONSThe World Health Organization (WHO) convened the 18th Bi‑regional Meeting of National Influenza Centres (NICs) and Influenza Surveillance for the WHO South‑East Asia and Western Pacific Regions from 9–11 September 2025. Hosted by the WHO South‑East Asia Regional Office (SEARO), the meeting brought together representatives from Member States, Territories, and Areas across both regions, alongside experts from the WHO Collaborating Centres for Reference and Research on Influenza in Australia and Japan, the WHO Collaborating Centre for Studies on the Ecology of Influenza in Animals in the United States, quadripartite partners (WOAH and FAO), and other technical counterparts. The consultation provided a platform to review progress, share experiences, and outline priorities for strengthening influenza and respiratory pathogen surveillance across the two WHO regions.Read moreNETWORKS AND TECHNICAL PARTNERSHIPSSTRENGTHENING PANDEMIC READINES: SOUTH-EAST ASIA ADVANCES UNITY STUDIES UNDER THE PANDEMIC INFLUENZA PREPAREDNESS INITIATIVEThe WHO Global Influenza Surveillance and Response System (GISRS) Investigations & Studies initiative, also known as Unity Studies, provides a standardized, globally coordinated framework to support these efforts. Originally developed for influenza and adapted during COVID-19, Unity Studies enable countries to conduct rapid, nationally led investigations and studies to assess transmissibility, severity, susceptibility, and intervention effectiveness. To better prepare for future influenza pandemics, WHO has recently launched a network of sites which will be ready to conduct these investigations and studies rapidly in the event of a pandemic, or epidemic of an emerging or re-emerging respiratory pathogen. The WHO South-East Asia Region now hosts six sites of WHO GISRS Unity Studies across the five countries including Sri Lanka, strengthening regional capacity for early pandemic investigations. From 13–16 July 2025 in Colombo, the Global Public Health Summit offered an opportunity to advance this agenda. Read moreSTRENGTHENING PANDEMIC PREPAREDNESS THROUGH UNITY STUDIES: REAL-WORLD APPLICATIONS FROM INDIA IN WHO’S SOUTH-EAST ASIA REGION As countries continue to strengthen their pandemic preparedness through investments in resilient health systems during the interpandemic period, the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS) Investigations & Studies Global Initiative, Global Initiative, commonly known as Unity Studies, remains a vital framework for respiratory pathogen pandemic preparedness. These standardized epidemiological protocols enable countries to rapidly generate high‑quality data on transmissibility, infection severity, population immunity, and the effectiveness of public health interventions. To highlight how Unity Studies protocols are being adapted and applied in national settings, WHO Headquarters, together with WHO Regional Offices, including the WHO South‑East Asia Regional Office (SEARO), hosted a global webinar. The session showcased case studies from India and the United Kingdom (UK), demonstrating innovative approaches to respiratory virus surveillance and pandemic readiness. Read moreSTRENGTHENING REGIONAL INFLUENZA SURVEILLANCE AND PREPAREDNESS: WHO SEARO HOSTS HIGH-LEVEL WEBINAR AMID RISING H5 THREATS In response to the increasing detection of avian influenza A(H5) cases in humans globally and within the WHO South‑East Asia Region, the WHO Regional Office for South‑East Asia (SEARO) convened a regional webinar on 25 July 2025 to review preparedness mechanisms, strengthen surveillance pathways, and promote timely reporting of unusual respiratory events. The virtual session brought together more than 50 participants from Ministries of Health, National Influenza Centres (NICs), National IHR Focal Points (NFPs), WHO Headquarters, WHO Country Offices across the Region, and WHO Collaborating Centres (CCs) for influenza. The webinar provided an opportunity to share situational updates, discuss surveillance gaps, and reinforce coordination mechanisms critical for early detection and rapid response to avian influenza threats. Read moreOther Key PIP Updates (July-December 2025)MEMBER STATES:Bangladesh drafted and conducted a series of Core Group Meetings in 2025 to review and update the National Pandemic Preparedness and Response Plan for Respiratory Pathogens. In addition, the country carried out Rapid Response Team (RRT) trainings on seasonal and avian influenza and other re‑emerging infectious diseases. Bangladesh also updated its epidemiological data‑training programme for physicians at sentinel surveillance sites, using a revised epidemiological data‑collection tool.Bhutan revised and updated its National Influenza Pandemic Preparedness and Response Plan (NIPPRP) in 2025 and developed a national Standard Operating Procedure (SOP) for influenza outbreak management. DPR Korea conducted a nationwide simulation exercise in July 2025 to support the update of its National Influenza Pandemic Preparedness Plan (2019). This followed a PRET‑based virtual orientation and mini‑simulation exercise held in May 2025 by SEARO and the WHO PRET Secretariat. The comprehensive exercise, conducted across central and provincial levels, assessed strengths and gaps in pandemic influenza preparedness and response. The feedback gathered has been incorporated into the revised draft plan to address identified weaknesses and strengthen overall readiness.India conducted a targeted nationwide online re‑orientation training on review and updates to the influenza portal for all State Surveillance Officers (SSOs) and relevant officials using the Integrated Health Information Platform (IHIP). The training emphasized correct marking and reporting of influenza samples as “unsubtypable” or “not subtyped” where applicable, to ensure accurate national surveillance.Maldives conducted simulation exercises in three atolls based on its existing National Pandemic Preparedness and Response Plan (NPPRP). The country plans to conduct similar exercises in three additional atolls after updating the NPPRP in 2026. In addition, Maldives conducted training on FluID and FluMart as part of a broader data‑management training package for Ministry of Health and Health Protection Agency officials, aimed at improving routine reporting to WHO platforms and the DHIS2 system.In Myanmar, technical support was provided to the National Influenza Centre (NIC) through dedicated human‑resource support (January–December 2025) to sustain data management and laboratory detection capacity for influenza and other emerging and re‑emerging respiratory viruses. This support also included strengthening genomic sequencing capacity.Nepal conducted a consultative workshop on the National Pandemic Preparedness and Response Plan (NPPRP) in July 2025. The workshop engaged key stakeholders from multiple sectors to review lessons from past pandemic responses, assess current mechanisms, and gather critical inputs for strengthening national preparedness. Key recommendations included revising the 2019 NPPRP and developing an updated Influenza Pandemic Preparedness Plan aligned with emerging risks, national priorities, and relevant international frameworks. Nepal also held a two day workshop dedicated to advancing the National Action Plan for Genomic Surveillance, aimed at reinforcing the country’s capacities for early detection and monitoring of emerging respiratory pathogens.Sri Lanka received the final report from WHO on the feasibility assessment for conducting an Influenza Burden of Disease (BoD) study in the country. The assessment, conducted from 28 April to 9 May 2025, included a desk review of existing data sources, document review, visits to sentinel surveillance sites, and key informant interviews. The study identified critical data sources required for a future BoD assessment, as well as their availability and quality. Officials from the Epidemiology Unit, the National Influenza Centre (NIC), and SARI/ILI sentinel hospitals across the country participated in the assessment.Timor Leste conducted on‑the‑job training and monitoring activities at two sentinel surveillance sites to strengthen surveillance and laboratory capacity for the detection of SARI, ILI, ARI, and other respiratory infections. REGIONAL OFFICE:SEARO conducted a Member States Consultation on the first draft of the Regional Roadmap and Strategic Action Framework for implementing WHO’s PRET‑based broad respiratory pathogen pandemic planning for 2026–2031. The consultation took place on 29–30 October 2025 during the final two days of the Regional PIP PC Annual Review and PRET Meeting in Colombo, Sri Lanka. Participants included representatives from Member States, WHO Country Offices, WHO SEARO, WHO Headquarters, partner agencies, and invited multidisciplinary technical experts. They reviewed the draft and provided detailed feedback, which has since been incorporated into a revised version. The consultation helped shape a shared regional vision for robust, PRET‑aligned pandemic preparedness, building on country‑level progress, addressing existing gaps and challenges, and aligning with global and regional health security frameworks. The publication is planned for release during the SEAR regional committee in 2026.SEARO documented the evolution of the National Influenza Pandemic Preparedness Planning process in the Region, tracing its development from its origins as a planning tool for responding to avian influenza outbreaks in 2006, through the experiences of the 2009 and 2019 pandemics, to the current status. The document outlines the way forward for respiratory pathogen pandemic planning across all 10 SEAR countries, aligning future national plans with WHO’s PRET Framework for broad respiratory pathogen pandemic preparedness.The Infectious Hazard Management (IHM) Unit has drafted the WHO South‑East Asia Regional Guidance on Influenza Prevention and Control, aligned with the Global Influenza Strategy and other regional initiatives. The draft is currently under review. Although this technical product was developed in response to a request from the Ministry of Public Health of the Democratic People’s Republic of Korea (MoPH‑DPRK), SEARO is finalizing it for use not only in DPRK but also across all Member States in the Region.The Immunization and Vaccine Development (IVD) Unit, in collaboration with WHE/SEARO, completed a regional landscape analysis on key barriers, challenges, and opportunities for the introduction of seasonal influenza vaccination in WHO South‑East Asia Regional (SEAR) countries.Additionally, the Immunization and Vaccine Development (IVD) Unit has completed a regional landscape analysis of influenza vaccine procurement systems across the WHO South‑East Asia Region (SEAR).KEY MEETINGS AND PUBLICATIONSMEETINGS:Six-month progress review of the implementation of the PIP-PC workplans in SEAR, focusing on Outputs 1 and 2 for the period January to June 2025, and held virtually across three sessions on 4, 8, and 10 July 2025. Read moreAnnual Regional Meeting (Hybrid) on Pandemic Influenza Preparedness (PIP) Partnership Contribution (PC) and WHO’s Preparedness and Resilience for Emerging Threats (PRET) Implementation in SEAR in Colombo, Sri Lanka, 27 to 30 October 2025. Read more18th Bi-regional Meeting (Virtual) of National Influenza Centres (NICs) and influenza surveillance in WHO South-East Asia and Western Pacific Regions from 9 to 11 September 2025. Read morePUBLICATIONSImplications of influenza A virus surveillance in Southeast Asian Region countries: a scoping review of approaches for the surveillance of swine influenza viruses at human-swine interfaces. Read moreAnnual South-East Asia regional meeting on operational planning for implementation of global influenza strategy and preparedness for respiratory viruses in 2025 Report on annual review meeting of implementation of pandemic influenza preparedness (PIP) partnership Contribution (PC) Fund in South-East Asia Region and the simulation exercise on PRET Status of influenza in who south-East Asia Region
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3L student Ediz Kalkan combined rigorous coursework, mentorship, and hands-on client experience to emerge ready for corporate practice. 3L student Ediz Kalkan shares how UC Law SF’s Business Law Concentration helped him gain the practical skills, doctrinal knowledge, and professional confidence to pursue a career advising corporate clients. It’s one of 12 concentrations that allow JD students to gain specialized expertise in a focused area of legal practice. 3L Ediz Kalkan built a strong foundation in corporate law through specialized coursework and mentorship from faculty and industry leaders. He gained hands-on client experience advising startups through the Startup Legal Garage and through roles in-house and at a law firm. He emerged prepared to handle sophisticated legal matters and interact confidently with clients. 3L Ediz Kalkan: I always gravitated toward business law courses at UC Law SF, so it made sense to memorialize that interest by completing the concentration — especially since I already planned to take most of the required coursework. I have taken many practical- and doctrinal-focused courses, including practical-oriented courses such as Mergers and Acquisitions, Venture Capital and Start Ups, Startup Business Lawyering, Private Equity and Hedge Funds, Corporate Governance, Corporate Finance and a few others. On the doctrinal side, I have taken Business Associations and am currently enrolled in Bankruptcy and Securities Regulation. These courses and professors equipped me with a strong foundation in universal corporate legal principals, fluency in the jargon, and insight into how corporate law intersects with markets, public and private companies, and government agencies. I also gained invaluable mentorship and lessons from industry leaders — both from the faculty and the dozens of guest speakers invited to the classroom. At UC Law SF, I participated in the Corporate Module of the Startup Legal Garage, where I observed practicing attorneys and helped real clients with real startup-related legal needs. I learned substantive law, business strategy — and most importantly — was socialized to the practice of law and the etiquette and expectations of being a junior attorney. I spent my 1L summer at AXOS Bank, a commercial bank in San Diego, where I gained experience with securities regulation, enterprise banking, and in-house work at a public company. From January of my 2L year to now, I have worked as a law clerk at Bartko Pavia LLP, gaining experience in a traditional law firm setting. I have had the privilege of working with startups all the way to public companies, as well as international clients. The experience has strengthened my confidence in tackling complex legal issues and interacting with clients. Through these experiences, I’ve learned that effectively advising clients takes more than subject-matter expertise. This work, and my time in the UC Law SF business concentration, have inspired me to pursue an MBA after law school to become a more well-rounded professional. My career plans remain focused on corporate practice and enhancing my value as a business advisor. I would happily recommend UC Law SF and this concentration because of its robust course catalog, highly successful professors and adjuncts, and extensive resources. Not to mention, UC Law SF is uniquely situated just minutes away from many of the world’s most innovative companies, all of which have legal needs — creating meaningful opportunities for students. My peers and I have been incredibly fortunate to have access to this network of industry leaders and legal professionals. Ultimately, business lawyers can take many paths, but all require the strong foundation that the business law concentration and the incredible people at UC Law SF provide. The Evidence of Success series highlights UC Law SF students as they share how the college’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.
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