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Julie Chen Moonves weighs in on Devens, Drew, and Taylor’s ‘Big Brother’ finale chances
Big Brother host Julie Chen Moonves weighs in on Devens, Drew, and Taylor’s finale chances and predicts who she thinks will win America’s Favorite Houseguest.
Fox Sports Radio launches ‘College Football with Stugotz & The Bear’ podcast
Jon “Stugotz” Weiner has moved on from his “hurtful” split from The Dan Le Batard Show, formerly The Dan Le Batard Show with Stugotz, and he’s making good on his promise to “build a f*cking empire.” On Thursday, Fox Sports Radio announced College Football with Stugotz & The Bear, distributed by iHeartPodcasts and debuting Friday, Sept. 25.…
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing
A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.
Capitol agenda: Dems weigh doing Husted a solid - Live Updates
A data center measure easily passed the House last week with more than 200 Democratic votes, but campaign-season politics are making action trickier for the party in the Senate.
Should FSU bring back Jimbo Fisher? History offers a cautionary tale
Florida State is reportedly weighing a Jimbo Fisher reunion. We studied 18 coaches who made a second run with a school. Almost none were successful.
JPMorgan says buy this sports data stock that looks cheap
The investment bank initiated coverage of the sports data and technology stock with an overweight rating.
Focus: Americans navigate 'wild West' of health insurance options after dropping Obamacare plans
When Stacy Cox, a self-employed photographer in Kanab, Utah, dropped her Obamacare health insurance plan this year, routine preventive care became a financial dilemma. Now she finds herself weighing $1,200 for a mammogram against survival of her business.
Data centers and health. A UConn professor weighs in on the controversy.
A consideration is that data centers are built where land is cheap.
Democrats weigh how to handle data center vote that could benefit a GOP foe
“They say they’re for more affordability,” embattled GOP Sen. Jon Husted said. “This is a chance for everybody to prove it.”
Surprising Short-Notice Welterweight Bout Added to UFC 332
A surprising short-notice welterweight bout has been added to UFC 332, which takes place next Saturday night.As first reported by MMAMania.com, welterweight prospect Jacobe Smith will return to the Octagon to face UFC newcomer Bruce Whitehead in a surprising booking that has MMA fans scratching their heads.Heavy’s Marcel Dorff further confirmed that Smith vs. Whitehead […] The post Surprising Short-Notice Welterweight Bout Added to UFC 332 appeared first on HEAVY.
Chris Weidman Explains How Josh Hokit Can Beat Ciryl Gane
UFC Hall of Famer Chris Weidman explained how Josh Hokit can defeat UFC heavyweight champion Ciryl Gane at UFC 334.With less than one year of UFC experience, Hokit will be fighting Gane for the undisputed UFC heavyweight title at UFC 334, which goes down on November 14 at Madison Square Garden in New York City, […] The post Chris Weidman Explains How Josh Hokit Can Beat Ciryl Gane appeared first on HEAVY.
Donald Trump Receives Stark Warning from Businesses After Diesel Export Ban
President Donald Trump is weighing a diesel export ban to calm soaring fuel costs. Still, America’s most influential business lobbies say the idea would backfire badly and leave consumers paying more ...
Political science professors weigh in on U.S. House recess
On Sept. 16, Speaker of the House Mike Johnson recessed the House of Representatives a day earlier than scheduled. He sent members of Congress home to their districts before the midterm elections. This decision came following Rep. Thomas Massie’s introduction of articles of impeachment against Secretary of War Pete Hegseth, primarily related to military action...
ACSH in the media: British Medical Journal, RealClearScience (and Health), plus more podcasts
From a weedkiller paper that cannot carry the weight of its headline to a PFAS rule that treats cookware like a biohazard, we've been busy. Here’s a look at some of our recent media appearances, including in the British Medical Journal (BMJ), RealClearHealth, RealClearScience, SacTown Talks and the Health Policy Podcast.
George Kittle weighs in on 49ers’ surprising early success
San Francisco 49ers tight end George Kittle weighs in on the team's early success.It’s only been about three weeks into the NFL season, and no team might be hotter than...
Vikings QB Kyler Murray Laughs Off Weird Baker Mayfield Comments
Minnesota Vikings QB Kyler Murray laughed off old Oklahoma teammate Baker Mayfield's comments about people not liking him ahead of Sunday's game in Tampa.
Tiffani Thiessen says she ‘got nothing’ for ‘Saved by the Bell,’ didn’t make ‘real money’ until ‘90210’
‘Saved by the Bell’ alum Tiffani Thiessen weighs in on what the cast members were paid
Health leaders address childhood obesity at Baton Rouge conference
One in three children in Louisiana are overweight or obese, officials say.
Greenfield takes stock of viral attention: Businesses, officials weigh in after coverage of lesbian bar Last Ditch takes national spotlight
Local leaders and business owners defend Greenfield's Last Ditch bar amid a viral dispute over Saturday night masking policies.
Flutter Entertainment Falls as Guidance Cuts and a Recent Downgrade Weigh on Sentiment
Flutter Entertainment (FLUT) is down 4.4% today. Here is some analysis on what might have caused this price movement.Analysis: The most likely driver is continuing fallout from Flutter’s lowered 2026 outlook and a recent analyst downgrade that highlighted repeated guidance cuts and a slower-than-expected FanDuel sportsbook recovery. This could also reflect investor concern that heavier spending to defend market share may keep profits under pressu
Bills TE Kincaid is once again pulling his weight in production
The fourth-year player is leading the Bills (2-0) with 12 catches and is third in the NFL with 225 yards receiving.
Semaglutide is improving the heart health of millions—but how? Experts are stumped
“Our analyses could not fully ascribe the effects of semaglutide on cardiovascular disease to known risk factors with any certainty,” one researcher said after exploring years of data. "These results suggest that semaglutide should be considered as a cardiovascular disease reduction drug and not just as a weight loss drug,"
UFC Champion Justin Gaethje Provides Latest Health Update
UFC lightweight champion Justin Gaethje provided his latest health update as fans eagerly anticipate seeing him fight again.Gaethje’s last fight came in June when he defeated Ilia Topuria via fourth-round TKO due to corner stoppage to become the undisputed UFC lightweight champion of the world.However, he has not fought since then and isn’t even sure […] The post UFC Champion Justin Gaethje Provides Latest Health Update appeared first on HEAVY.
UFC Champion Justin Gaethje Provides Latest Health Update
UFC lightweight champion Justin Gaethje provided his latest health update as fans eagerly anticipate seeing him fight again.Gaethje’s last fight came in June when he defeated Ilia Topuria via fourth-round TKO due to corner stoppage to become the undisputed UFC lightweight champion of the world.However, he has not fought since then and isn’t even sure […] The post UFC Champion Justin Gaethje Provides Latest Health Update appeared first on HEAVY.
‘The Three B’s’ Combined XI
Everyone has been talking about Brighton, Brentford and Bournemouth, largely due to their consistent ability to punch above their perceived weight. But what is the best eleven that could be fielded using only players from each club?
Minnesota man excited for the future after bariatric surgery
For Paul Nistler, losing weight with bariatric surgery meant lifelong changes but also lifelong health and more time with his family.
Civic Committee sounds alarm on city finances ahead of budget
As Johnson and the City Council get ready for what promises to be another chaotic budget process, the Civic Committee weighs in with some friendly but stern advice.
Civic Committee sounds alarm on city finances ahead of budget
As Johnson and the City Council get ready for what promises to be another chaotic budget process, the Civic Committee weighs in with some friendly but stern advice.
'Forgotten Island' review: DreamWorks delivers an epic adventure for weirdos
Plus, Dave Franco in the oddball role he was born to play.
Meta is trying VR glasses (again), this time with more IMAX
Meta's return to the VR glasses realm comes with a promising combination of light weight form factor and enhanced entertainment options.
South Korea’s weight-loss obsession and the health risks it brings
South Korean women face higher underweight rates than men, with experts warning that social pressure to be thin and weight-loss drugs may pose health risks.
Chamber of Commerce, oil groups urge Trump to reject diesel export ban
American business, energy and manufacturing groups on Wednesday urged President Trump to reject calls to impose a diesel export ban after the president said he was weighing this move in an effort t…
Success of Weirton business opening doors for other opportunities, leaders say
A new business on Weirton’s Park Drive is marking more than a year in operation, and local leaders say its growth is helping strengthen the city’s economy while
Hearing on NextEra-Dominion utility merger scheduled in Fairfax
Virginia's state regulatory body has scheduled a Northern Virginia hearing as it weighs a proposed merger between Dominion Energy and Florida-based NextEra Energy.
The Cubs and Red Sox will play a doubleheader Friday
This crazy Cubs season gets a little bit weirder.
Atlanta Braves’ Walt Weiss Outlines the Plan for Robert Suarez
Atlanta Braves right-hander Robert Suarez is back.
Crew Studies Advanced Health Tech and Gears Up for Next Crew Swap
Ultrasound scans using augmented reality and artificial intelligence topped the health research schedule aboard the International Space Station on Wednesday. The Expedition 75 crew also collected blood and saliva samples to study how the immune system adapts to weightlessness. The orbital residents are now preparing for a crew swap as NASA’s SpaceX Crew-13 mission announces a launch date.
UFC Veteran Encourages Gable Steveson to Leave Jon Jones
UFC veteran Matt Brown has encouraged heavyweight prospect Gable Steveson to leave Jon Jones and find someone else to coach him. Steveson was shockingly defeated by Sean Sharaf on the UFC 331 main card this past Saturday in the biggest upset in UFC history, based on the odds. Following the bout, Steveson left the cage […] The post UFC Veteran Encourages Gable Steveson to Leave Jon Jones appeared first on HEAVY.
Harvey Weinstein sentenced to 15 years after being convicted of sexually assaulting ex-“Project Runway” staffer
The disgraced producer appeared in court on Sept. 23.
Health Watch: Lumin Health
Dr. Benjamin Yudkoff, MD, MA (Co-Founder & Chief Medical Officer, Lumin Health) joined Fox 5 DC.
Early childhood BMI trajectories predict later cardiometabolic health risks
Childhood obesity predicts later cardiometabolic disease, but single-time weight measures may miss dynamic growth information.
For The First Time, Scientists Have Looked Inside Living Antarctic Cells And Found Incredible Adapations
Antarctic dwellers are wonderfully weird, and it shows in their cells.
NH Libertarian Party endorses ‘assassination’ of elected Democrats
The state Libertarian Party has issued repeated calls for political violence in social media posts.
Harvey Weinstein sentenced to 15 years for sexual assault after retrial
Harvey Weinstein has been sentenced to 15 years behind bars.
Exceptional Earnings and AI Immunity Fuel Hinge Health’s (HNGE) Performance
Osterweis Capital Management, an investment management firm, released its Q2 2026 investor update for its “Osterweis Opportunity Fund”. You can download a copy of the letter here. The fund returned 35.34% in the quarter, significantly outperforming the Russell 2000 Growth Index’s 25.71% gain. Robust corporate profits, AI investment, easing oil-shock concerns, strong labor markets, and […]
Omada Health President Wei-Li Shao Sells 9,418 Shares for $236,000
Despite selling over 9,000 shares, the insider still holds 307,372 shares.
Alien sunsets, stone spiderwebs and mysterious doors: Curiosity's top 10 photos after 5,000 days on Mars
Curiosity has been photographing Mars in its search for evidence of water and life for over 5,000 Martian days. Here are 10 of the most surprising and weird photos the rover has sent back to Earth.
JPMorgan Weighs Opening Card Business to Private Credit
J.P. Morgan Chase is reportedly exploring whether other funding sources could approve some of the cards it rejects. That's according to a report late
AI Boom, Politics, Inflation Stoke Anxiety Across Big Law
AI’s ascendance, polarized politics, and stubborn inflation are weighing down legal professionals, survey shows.
DA Larry Krasner faces an uncertain political future as Democrats weigh what could come next
New questions emerged this week about Krasner’s political ambitions and his potential bid for Philly mayor. Meanwhile, others are angling for his job.
Horiguchi Returns Versus Almabayev At UFC Qatar
The UFC Flyweight division is hot right now. Just days ago at UFC 331, Joshua Van cemented his rule atop the 125-pound roost with a violent decision win over former divisional kingpin Alexandre Pantoja. Van is expected to face Manel Kape in his next title defense, but otherwise, the division is wide open for any […]
Stanford researchers weigh AI applications in education, science
As AI becomes increasingly capable, Stanford researchers explore how it can extend human capabilities in education, science and the social sciences.
Detroit Pistons Slip Weight Clause Into Jalen Duren Contract
With training camp opening next week, the Detroit Pistons still have not been able to reach a long-term agreement with restricted free agent Jalen Duren
Russia's neighbor reveals personal appeals to Trump as US weighs NATO troop pullback in Europe
Lithuanian President Gitanas Nausėda revealed he sent two letters to Trump urging U.S. troops to stay on NATO's eastern flank amid Russia threat.
Qualcomm releases Android chip built for AI as memory shortage weighs on smartphone market
The overall smartphone market is expected to contract 14% in terms of units shipped in 2026.
Is the priority health care or profit?
My head is spinning. First, finger-pointing and counter-finger-pointing. Now a court ordered receiver — no wait, a sale agreement for West Sub and Weiss has been agreed upon (aka “the check is in the mail”). In the continued shenanigans about these two hospitals and with recriminations flying in both directions, there appears to be no […]
Apple Watch Series 10 vs. Series 12 Buyer's Guide: Should You Upgrade?
The Apple Watch Series 12 is now available, two years after the Series 10 introduced the current thinner design. But is it worth upgrading? While last year's Series 11 brought just four changes, the Series 12 is a much more substantial update, with a new chip, twice as much RAM, redesigned health sensors, exclusive health and audio features, tougher cover glass, 5G connectivity, and new case materials. The Series 12 starts at the same $399 price as the Series 10 did in 2024.
This Weird Toad Drove a Brilliant Scientist to His Death. What If He Was Framed?
Paul Kammerer was one of the premier biologists of his generation. But his ideas made him some enemies.
When treachery abounds, entertainment resounds - The Voice of San Francisco
Betrayal is disheartening and debilitating, unless it’s happening to someone in a movie. Then, it’s diverting. For example, The Weight is a tension-loaded drama that follows a criminal expedition into the wilds of the Pacific Northwest in the 1930s and hinges on shady people depending on each other in extreme circumstances. As for The Musical, […]
Texans throw some weird bulletin-board material after Bengals beatdown
A comment in the aftermath of the Bengals routing the Texans is starting to get attention.
Poor sleep health in late pregnancy linked to higher childhood obesity risk
New research has found that mothers with poor sleep quality in late pregnancy had babies with lower weight in the first 6 months of life, but higher weight after age 1-2 years.
Can AI Be Slowed Down? Stanford HAI Experts Weigh the Risks, Rules and Race Ahead
In a new series called 'Prompt Response,' Stanford’s Surya Ganguli, Diyi Yang and Rob Reich examined emergent agent behavior, recursive self-improvement, independent evaluation and whether a 'kill switch' can make advanced AI safer.
Portsmouth housing solutions, AI threats, political views: Letters
Letters package: Writers weigh in on Portsmouth housing policy, AI risks, NH politics, Maine fisheries and international affairs.
MORNING BUSINESS REPORT: Seniors use weight loss drugs, Apple settlement, Disney trip deals
More seniors are using drugs like Ozempic, customers can claim part of an Apple settlement, and Disney offers promotional deals. Here's the Morning Business Report for Sept. 22.
Is 50 the new 60?
Subscribe TL;DR: Younger generations are showing signs of worse health compared to earlier-born cohorts at the same age This backward “drift” is showing up both in mortality risk and chronic disease Worsening trends in obesity and diabetes are the most consistent signals Taking the long view, we’ve made astonishing gains in health and life expectancy in the last century. Global average life expectancy has more than doubled from 32 years in 1900 to 73 years in 2024. (But don’t forget, there were still old people when life expectancy was 32). As people lived longer, they also generally lived healthier along the way. It turns out that avoiding things that can kill you early, like malnutrition and lots of childhood infections, also keeps you healthier later in life. In a classic 2004 paper, Finch and Crimmins proposed that cohorts of children who benefited from fewer early life infections had less lifetime exposure to inflammation and cardiovascular disease later in life, accelerating mortality improvements at older ages. Poor nutrition in the womb has also been linked to a higher risk of later chronic disease. The upshot is that improvements in childhood health can pay dividends many decades later. The combination of better living conditions (nutrition, sanitation) and medical advances (antibiotics, vaccines, blood pressure meds, etc) meant that people’s healthy lifespan generally expanded, even as they lived longer. Aging researchers call this best-case scenario “compression of morbidity”—meaning we delay the onset of disease and disability even faster than the years of life we are adding. During my 20+ year research career, we could generally bank on the idea that younger generations would not only live longer but also keep getting healthier along the way. “60 is the new 50” as they say… Enter “Generational Health Drift” Sadly, this expectation of steady progress may be changing. You’ve probably heard that US life expectancy gains have slowed to a crawl in the past couple of decades. Mortality improvements are also slowing (though less dramatically) in many other high-income countries (you can read more about that in a review paper I wrote here). Mortality is a very blunt health measure, but it is often a good barometer for the broader population health trends happening underneath. And we are now seeing that younger generations may be in worse health at similar ages compared to earlier born cohorts. My collaborator Prof. George Ploubidis at University College London coined this worsening health in more recently born cohorts “generational health drift.” “Generational health drift” is bad news on multiple fronts. Most obviously, we don’t want our health progress to go backward. But the timing is also bad, since our populations are aging. In demographic terms, “population aging” means that the proportion of the population at older ages (i.e >65 years) is increasing. Fun demography fact: Current population aging is not due to the recent declines in the birth rates making the news, but declines in fertility decades ago, after the “baby boom.” As baby boomers reach older ages, the smaller cohorts behind them mean the percentage of older adults will increase. For example, the share of the population age 65 and older in the US increased from 12.4% in 2004 to 18.0% in 2024. This story of population aging was written long ago. Many worry that population aging will put pressure on health care and pension systems. But if people reach older ages in better health than in years past, those fiscal pressures would be less dire than projected. Healthy older people can also continue to contribute to society in many valuable ways, including paid work, caregiving, community service….even high political office 🤷. On the flip side, if younger generations reach retirement age in worse health and with more disabling conditions, this could magnify the societal challenge of population aging. Evidence for worsening generational health A recent paper that I LOVED in the Proceedings of the National Academy of Sciences by Dr. Leah Abrams and colleagues examined which birth cohorts (aka generations) were behind worsening US mortality. Behold the Lexis diagram (cue swooning demographers). Calendar time is on the x-axis, age on the y-axis. Birth cohorts can be followed over time as they age on the diagonal lines moving up and to the right. This figure plots the year-on-year % change in all-cause mortality at a given age. Green shading indicates mortality improvements over time, white is stagnation, and gray shading indicates worsening mortality. Following the diagonal line for those born in 1950, you can see a noticeable shift from green to gray that follows this cohort for most of their lives. This gray shading shows generally worsening mortality for the 1950 to 1959 birth cohorts compared to their predecessors across all ages. Concerningly for my GenX and elder millennial peeps, there was also a deterioration in mortality for birth cohorts born in the 1970s and 1980s, visible as dark gray areas at ages 30 to 45 during the 2010s. While some of these mortality changes reflect specific shocks such as the opioid epidemic, most deaths still occur from major causes of death such as cardiovascular disease and cancer. For cancer, the gray in the top left corner of the figure below reflects the legacies of smoking for older cohorts, followed by a period of green with improvements in cancer mortality as smoking rates declined. But the white/gray shading in the bottom right corner highlights a stagnation and reversal of the cancer trends, with cohorts born around 1970 to 1985 experiencing worsening cancer mortality. This deterioration was most noticeable for colon cancer mortality, possibly linked to obesity or dietary factors. Not just dying more, but less healthy along the way. A recent paper by Dr. Laura Gimeno of University College London (of which I am a co-author), found evidence that more recently born cohorts in Great Britain have stagnating or worsening health. A stylized picture of what“generational health drift” might look like: The review paper found: Rates of childhood overweight and obesity were highest among Gen Z. Rates of diabetes in the 40s almost doubled from 3.1% among the Baby Boomers to 5.9% in Generation X. Gen Z reported higher rates of poor mental health in adolescence compared to earlier-born groups. These UK results are consistent with studies showing worsening health across generations in the US as well. A 2021 US study found that more recently born cohorts had worse biological markers (like blood pressure and blood sugar) than earlier generations at the same age. A separate 2022 study of Americans aged 50 and over found that more recently born generations had a higher number of chronic diseases, with younger age of disease onset. A 2024 Lancet paper found that in the US, women born in 1945 had 33% obesity prevalence at age 50, rising to 48.2% for women born in 1970 turning 50. So what’s going on, and can we turn it around? We don’t have a definitive answer for what’s causing the deteriorating health of younger cohorts, but circumstantial evidence points to worsening trends in obesity and diabetes in both the US and UK. Remember that cohort trends reflect lagged effects of early environments, and younger generations have faced both earlier onset and more severe obesity across their lifetimes. Despite these very concerning trends, the future is not set in stone. We’ve reversed poor generational health trends before: drops in smoking are a major reason cancer and heart disease deaths fell so dramatically in recent decades. GLP-1 drugs may finally turn the tide against rising rates of obesity and diabetes, though it is still early days. But things could also get worse…for example from a return to higher levels of childhood infectious diseases that can have a lasting impact on health. See for example: [ ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) [ Don’t You Forget About Me(asles): The Virus That Erases Immune Memory ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Jenn Dowd, PhD · March 24, 2025 [ Read full story ](https://jenndowd.substack.com/p/dont-you-forget-about-measles-the) Even as an optimist, emerging data on the “generational health drift” has my full attention. For most of my research career, we took it for granted that each generation would be healthier than the last. But if present trends continue, **50 could be the new 60….**and Gen Z celebrities will soon look older than Paul Rudd :). Stay well, Jenn Share the Health! If you found this post useful, please share it with a friend. Share
Newsom eyes 2028 as Democrats weigh their political future
Join The Hill’s Ian Swanson, Amie Parnes and special guest Democratic strategist Garry South, who has advised California Gov. Gavin Newsom (D), for a special “Fight for 2028” centered o…
Minogue calls for federal probe into $2B state contract awarded to political heavyweights
Republican gubernatorial candidate Mike Minogue is calling on U.S. Attorney Leah Foley to investigate “everything around” the $2 billion state contract awarded to politically connected bidders.
How lip-syncing to AI let Forced Entertainment ‘play the game of theatre’
Today we have a fascinating piece by long-time Forced Entertainment fan Ben Kulvichit, speaking to Tim Etchells about their latest show Cold Sweat, how they are integrating lip-sync and AI voices into their work, the question of ‘authenticity’ on stage, and how lip-sync has even opened the door for them to make “something a little bit like drama”. This piece is a paid partnership with the Southbank Centre, where you can see Cold Sweat next month – we’re very grateful to the Southbank Centre for their ongoing support for Exeunt. Holly Williams ‘It was immediately interesting and uncanny’ **By Ben Kulvichit** “Is the microphone on?” So goes one of the opening lines of Signal to Noise, delivered by a human performer lip-syncing to an AI-generated voice. The voice is American, cheery but sluggish, slowed down into a gelatinous drawl. It repeats ad infinitum in a farce of stuckness; an answer never materialises. I find myself asking the same question as I hop on a Google Meet call with Tim Etchells, the artistic director of Forced Entertainment. We spend five or ten minutes frowning at each other, muting and unmuting, me gesticulating in semaphore into my webcam, checking if I am coming through now, restarting the laptop. To Etchells, I appear exaggeratedly mouthing words, my voice missing. In this gloopy purgatory of broken communication, life imitates art imitates life imitates art. We try a Zoom instead. Forced Entertainment, the pioneering British theatre company who have been at the avant-garde of performance since the 1980s, turned an interesting artistic corner with Signal to Noise, created on the occasion of their 40th anniversary. The whole performance employed this lip-sync technique to AI voices; on the face of it a left-field move from a company whose identity has long been grounded in the earthy, immediate presences of its performers and its unassuming, low-tech approach to theatricality. The technique, however, turned out to provide the company with a “rich new seam” of artistic enquiry, and has now spawned a trilogy of works. The second instalment, Cold Sweat, plays at Sheffield Theatres, Southbank Centre, and Lancaster Arts in October, while the third part, Everything Must Go, has been touring in Europe and is slated to come to the UK in 2027. As is often the case with Forced Entertainment shows, the main conceit for this work didn’t arrive until quite late. They were “four or five weeks into rehearsals for Signal to Noise,” Etchells recalls, and getting nowhere. Away from rehearsals, he had been playing around with feeding “weird texts” to AI voices to see how they would cope with them – “basically for my own amusement” – and was compelled by the uniformly “serviceable, benign, good-natured” tone they would read in, no matter how poetic, fractured or experimental the writing. On a hunch, he brought some examples into rehearsals and the performers gave lip-syncing a go. “It was immediately interesting and uncanny,” he recalls, with the performers having to deal in the moment with the problem of mapping themselves onto another artificial ‘performer,’ which itself was dealing with the problem of a very human text. “Almost all the writing for these projects would be useless to us unless it was done in this way,” says Etchells. “We wouldn’t know what to do with it. It’s too poetic. It’s too fictional. It’s too tangled.” But exploring lip-syncing along to the text has opened “an enormous reservoir of ways of thinking about writing and performing.” Subscribe to Exeunt, and get two in-depth pieces on theatre a week, direct to your inbox Subscribe Forced Entertainment have long been sifting through the detritus of popular culture, from daytime TV to end-of-the-pier vaudeville, magic acts and clown shows, to find frameworks for their own unusual entertainments. Lip-syncing, then, makes sense for them to experiment with. As a mode of performance, it’s wired into popular consciousness through pop stars trying to convince stadium audiences of their liveness, or those same voices as channeled through the made-up lips of contestants on RuPaul’s Drag Race, or movie dialogue spreading virally through the host bodies of TikTok users. For Etchells, lip-syncing is often about “approaching real voices and trying to take on their aura,” subsuming that original human presence into yours. “There’s a very basic, elemental sort of theatre magic to it, produced in this very easy way.” This broad approach resonates with instances of lip-syncing within contemporary performance, too. In works like Re-Member Me and Showmanism, performance artist Dickie Beau acts as a kind of spirit medium for archival recordings (this process of re-membering – as in, giving corporeal form to voices – relies on his masterfully precise actor’s technique), while Frankie Thompson is similarly possessed by a host of characters ranging from a nine-year-old Jacob Rees-Mogg to Cliff Richards, all of whom she finds compellingly nauseating, in the exorcism ritual that is her latest show, Horrible Things. What’s different about Forced Entertainment’s use of lip-syncing is that here, there is no original presence to be channeled. The performers are instead taking on what Etchells describes as “the voices of nobody,” or rather the “phantasmic, aggregated echoes” of the many many voices on whose data the AI has been trained, and which are now conjuring into existence words they never actually said. There is a sort of mournful, empty quality to these voices, having “washed up” far away from the people they originally belonged to, to find themselves in stranger’s mouths listing objects, wondering if anyone can hear them and glitching in interminable loops. There is a cold, sad anonymity to it all. Etchells remarks that occasionally the software company he used has notified him that particular people are withdrawing their voices from the platform, instructing him to cease use of those voices. Using these technologies in performance certainly brings up ethical questions around digital rights, consent, identity and ownership, although in the grand scheme of things, Etchells is fairly blasé about it: of all the purposes someone’s voice might be put to without their knowledge, “an avant-garde performance is probably the least of their worries.” [ ](https://exeuntmagazine.substack.com/p/frankie-thompson-horrible-things-essay-mental-health-compulsive-behaviours-pleasance-courtyard-soho-theatre) [ Frankie Thompson: How I manage my own ‘horrible things’ at the Edinburgh Fringe ](https://exeuntmagazine.substack.com/p/frankie-thompson-horrible-things-essay-mental-health-compulsive-behaviours-pleasance-courtyard-soho-theatre) Exeunt · Aug 25 [ Read full story ](https://exeuntmagazine.substack.com/p/frankie-thompson-horrible-things-essay-mental-health-compulsive-behaviours-pleasance-courtyard-soho-theatre) For the performers, though, lip-syncing to these strange, artificial voices is an odd task, requiring them to bend their live, human presence into the shapes produced by machines. Politically, it mirrors processes that are already at play in the continued computational automation of human life. Etchells brings up James Bridle’s writings on new technologies as a reference point: one example Bridle gives is of “chaotic storage”, a logistics technique employed by Amazon fulfilment centres whereby items are stored not according to traditional methods of categorisation or alphabetisation, but in a way that an algorithm determines to produce the most efficient routes for ‘picking’ based on customer purchase patterns. This appears completely random and incomprehensible to humans, with paddling pools sitting next to USB sticks sitting next to blowtorches, and so for the warehouse workers, the process of picking items becomes completely reliant on technology which tells them where to go. Our world is increasingly being designed not with humans in mind, but rather machines. As Etchells puts it, “technology malforms the space, and then you end up having to live in it.” Initially, Forced Entertainment tried their best to live in the world of machines: “I was in the it’s-got-to-be-perfect school of lip-sync,” says Etchells. But with their aesthetic being so tied to the failing act, the slipping mask, the shoddy costume, “it’s no surprise really that that didn’t last.” Instead, the performers got to enjoy being late for a line, or playing games with each other, “stealing” each other’s voices. Etchells compares it to the principles of ventriloquism, in which a free-floating voice unattached to a body is fundamentally discomforting and “sort of traumatic”. That discomfort is equally as alluring to Forced Entertainment as the satisfaction of precision, the pretence of authenticity only interesting if shown to be a pretence. Lip-sync has also opened up new avenues for the company. Having been allergic all their lives to Plays-with-a-capital-P, with Cold Sweat Forced Entertainment find themselves approaching something a little bit like drama. Rather than the presentational arena of Signal to Noise’s open white stage, Cold Sweat places us more decisively in a “fictional locale”: what appears to be “the aftermath of some disastrous party or backyard drinking binge” where three figures – family members, or neighbours, perhaps – are the last ones standing. “It’s all quite acrimonious and accusatory, everyone’s talking over each other.” For Etchells, this more fictional mode is “a door that we’ve never been able to open. We’ve just never really gone there.” Perhaps it is the technique of lip-syncing, an extra buffer of mediation, that allows them to venture away from the here-and-now without feeling that they have to commit to the “psychological claptrap” that comes along with acting; to be able to “play the game of theatre, without getting one’s hands too dirty.” As I wonder how else the impulses behind Forced Entertainment’s work have changed over time, it occurs to me that over the last ten years of new creations, with the exception of If All Else Fails, the company’s performers haven’t ever spoken on stage: there were two shows without any language at all, Out of Order and Under Bright Light, and then this trilogy of lip-sync works. Etchells agrees it’s a shift away from earlier productions, that were so often about “the actual voices of the performers and their actual presences. We had a lot of money, in some ways, on an authentic approach to what it might mean to speak on the stage.” But this sense of authentic presence itself had a fakeness to it; these days, Etchells can’t stand that mode of being onstage where performers “are here to be cheeky and witty versions of themselves. I don’t want to be charmed.” Pulling back into a more anonymous space has resulted in works that feel slightly sharper-edged, more brutal in a way. “All of these shows are post-Brexit, post-Trump, post-truth, post-everything,” Etchells notes. Speech, charisma, authenticity – these things feel politically loaded, and perhaps warmth and openness just don’t feel like the right tools to reflect the world we’re living in. “It feels like the space is closing down, and we’re trying to deal with the fact that the system, the structure that you’re in, is more oppressive and more powerful. It probably always was, but I think we’re just more tuned to it now.” Yet even without their voices, the performers’ distinctive presences – ones that many audiences have followed around for years, if not decades – still, inevitably, shine through as they physically navigate whatever unending task the system of the piece has set for them. They’re still trying to keep up with the onslaught of text, still running about, changing costumes, moving stuff around. The human is always stuck in the teeth of the machine, jamming the smooth, frictionless cheeriness of the not-real, gesticulating silently, trying desperately to communicate. Cold Sweat is at Sheffield Theatres, 2 to 3 October; Southbank Centre, London, 9 to 10 October; Lancaster Arts, 14 October [ ](https://exeuntmagazine.substack.com/p/exeunt-recommends-the-best-autumn-theatre-2026-lives-of-others-standard-of-living-our-friends-in-the-north-lanny-) [ Exeunt recommends... the best autumn theatre ](https://exeuntmagazine.substack.com/p/exeunt-recommends-the-best-autumn-theatre-2026-lives-of-others-standard-of-living-our-friends-in-the-north-lanny-) Exeunt · Sep 16 [ Read full story ](https://exeuntmagazine.substack.com/p/exeunt-recommends-the-best-autumn-theatre-2026-lives-of-others-standard-of-living-our-friends-in-the-north-lanny-) This piece was paid for by the Southbank Centre. Such support helps Exeunt to keep publishing the most interesting writing, about the most exciting theatre. Interested in partnering with Exeunt? Visit our Advertise with Exeunt page, where you can get more information, download an advertising pack, and find our contact details.
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