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Ex-Liverpool boss Jurgen Klopp rubbishes Real Madrid links
Former Liverpool manager Jurgen Klopp has dismissed speculation linking him with the Real Madrid head coach job this summer.The German tactician branded the rumours nonsense as publications continue t...
We disagreed on politics. We agreed on wine. That was enough.
At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.
35 Products I Bet You Haven’t Seen Yet, But I Also Bet You’ll *Love*
Nobody panic, but Summer Fridays just released a caramel-vanilla perfume.
Charlotte native and rapper DaBaby announces music festival coming to Concord this summer
CONCORD, N.C. (QUEEN CITY NEWS) — Charlotte native and rapper DaBaby is bringing a major hip-hop festival to the area this summer. The Grammy-nominated rapper, who will be kicking off a nationwide tou...
Former political rivals take on Trump’s push to nationalize voting
GOP lawyer Ben Ginsberg and former Obama White House counsel Bob Bauer aim to present a united front against the Trump administration’s efforts to oversee election administration
Kraken assume majority ownership of Climate Pledge Arena
The Seattle Kraken ownership group, led by Samantha Holloway, announced the creation of One Roof Sports and Entertainment on Monday.
Rock and roll icon to perform in central Pa. concert this summer
The tour is in support of his new album, “Automatic,” his first original release in five years.
Pop superstar announces summer concert tour, including stop in central Pa.
"The Freedom Tour" will make a stop in Hershey this August.
How to beat Gigantamax Pikachu: Best Counters & Guide
Gigantamax Pikachu is a Tier 6 Max Battle in Pokémon GO. It will cost 800 Max Particles to participate in this Max Battle, which will only be consumed if you defeat Pikachu successfully. Gigantamax Pikachu can be shiny from Max Battles. Being an type, it is only weak to type moves. Pikachu can be caught […]
Funding for populist-right ‘media-political complex’ exceeded £170m in five years, research finds
Handful of billionaires gave huge sums in particular to media organisations that boosted rightwing politicians, says Liam Byrne MP
Scientists Open Moon Rocks Locked Away Since 1972 – and Find Something Totally Unexpected
Decades after being sealed away, Apollo-era lunar samples are revealing unexpected chemical signatures that challenge long-standing assumptions about the Moon’s composition.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Scientists twisted a mysterious superconductor and got a shocking result
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'Completely lawless': Why this congresswoman wants Pam Bondi impeached
From the Epstein files to the integrity of prosecutions, Democratic Congresswoman Summer Lee says Attorney General Pam Bondi is damaging the DOJ.
Eddie Hall Teases Summer MMA Return, Dillon Danis Fight
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Former OSU athletes talk mental health at Scioto County Mindset Matters Summit
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Austin soul food staple Hoover’s Cooking to close after nearly 30 years
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RJ promotes Traci Wilson to vice president of digital strategy
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Apple Wanted to Buy Halide to Boost iPhone 18 Pro's Camera App—Now There's a Lawsuit
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At age 41, a Westmoreland mom of 3 is diagnosed with a cancer that's rising in younger populations
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Tottenham eye transfer move for Freiburg’s Noah Atubolu
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Scientists just found a hidden 48-dimensional world in quantum light
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Swalwell plays up athletic credentials in effort to blunt DHS sweeps at World Cup
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Politics Friday: Consumer safeguards gain bipartisan support at the Capitol
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Cristiano Ronaldo misses out on Portugal friendly vs. USMNT and Mexico due to injury
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Unilever Has $40 Billion in Tasty M&A Options
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Player availability report, presented by Orlando Health Orlando Health Jewett Orthopedic Institute: Orlando Pride vs Denver Summit
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Verdict on Chatbots in Mental Health Screenings? Too Judgmental
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Brooklyn businesses, consumers feeling the pinch from soaring oil prices
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AI-generated follow-up questions and answers
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How will the Iran war widen the rift between the US and China?
Trump asks to delay planned summit with Xi
2026 Financial Summit: Strengthening Small Business for a Changing Economy
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Will the Allina-Sutter Health deal drive up the cost of health care in Minnesota?
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Gas is so expensive even oil companies may suffer
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Rangers looking at Just
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Flyers' Trevor Zegras welcomed back in Anaheim return
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Prep baseball roundup: Sherman Oaks Notre Dame is off to a 9-0 start
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Rising fuel prices impact businesses and consumers in Greater Cincinnati
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Cal State Monterey Bay partners with Montage Health to expand nursing education
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Ever Joint Claims Evaluated: What the Science Says About EverJoint Joint Support Ingredients
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Summer Lee in Congress from Pittsburgh to Washington
Summer Lee is a Democratic U.S. House member for Pennsylvania’s 12th District, covering parts of Pittsburgh and Allegheny County elected in 2022.
Seth Cohen to become new dean of UC Irvine's School of Physical Sciences
Renowned leader in advanced chemistry research will assume new role Aug. 1
Georgia meets Saint Louis in anticipated track meet
Georgia coach Mike White offered up a quick summation of Thursday night's NCAA Tournament Midwest Region first-round game against Saint Louis in Buffalo, N.Y.
Looking for leverage: China keeps close eye on US politics after summit delay
Beijing seeks to decipher effect of Iran war on US midterms and best way to apply pressure when Trump meets Xi
Marquee Sports Network now available on Hulu + Live TV
The regional sports network's direct-to-consumer service is now also available for purchase on Prime Video.
Birth control skepticism, teen fertility education center stage at Trump’s women’s health summit
Seeking to reach women at a moment when President Donald Trump’s support is slipping among a key voting bloc, the Make America Healthy Again movement, the administration-sponsored event elevated perspectives outside conventional standards of medical care and counter to many women’s health choices.
Oil prices hold steady even as Iraq resumes some exports via Turkey
Oil prices held steady Wednesday after Iraq clinched a deal to resume some crude exports via Turkey. It’s not a ton of oil, but it’s what amounts for good news these days as the Strait of Hormuz remains largely blocked.
TikTok's global consumer marketing head is out, part of job cuts
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Oil price falls after Iraq ‘signs deal’ to resume exports via Turkey
Rolling coverage of the latest economic and financial news
Gossip: Spurs could target Savinho in summer
Manchester City could let Brazilian winger Savinho, 21, leave in the summer and Tottenham are possible suitors if they retain their Premier League status. (Football Insider)
Why Denver should care about conservation easements — even if you’ve never set foot on a ranch
By Jason Swan I live in Denver. I drink tap water from my kitchen sink, hike close to home when I can, worry about wildfire smoke every summer, and try, like many families, to keep up with the rising cost of living. I don’t own land. I don’t ranch. I don’t farm. And yet one […]
Inside JB Pritzker’s power play in Illinois’ Senate primary – and what it means for a 2028 run
Many assume JB Pritzker’s run for president is just a year away. His effort to engineer a victory for his lieutenant governor, Juliana Stratton, in Illinois’ Senate primary was also a victory for him and a political operation with national ambitions.
Stada Hunts for Major Consumer Health Deal After Record Profit
German pharmaceutical firm Stada said it’s ready to make a major consumer health acquisition as it books record profit and transitions to new ownership.
Judge Orders Voice of America to Restart All News Operations
More than 1,000 full-time journalists and support staff at the news group were ordered to return to work by March 23 and to resume broadcasting.
Your daily coffee may be protecting your brain, 43-year study finds
Your morning coffee or tea could be quietly supporting your brain health. A long-term study found that moderate consumption of caffeinated coffee or tea was linked to an 18% lower risk of dementia and better cognitive performance over time. The benefits appeared strongest at 2–3 cups of coffee or 1–2 cups of tea daily—and even held true for people genetically predisposed to dementia.
Let the games begin: Foxboro signs off on entertainment license for FIFA
The 2026 FIFA World Cup is officially coming to Gillette Stadium this summer after months of uncertainty.
Health officials urge consumers to avoid raw cheddar tied to ongoing E. coli outbreak
L.A. County health officials are urging consumers not to eat Raw Farm-branded raw cheddar cheese after the product was linked to an ongoing outbreak of Shiga toxin‑producing E. coli. This type of b…
Exclusive: Small publishers hit hardest by search traffic declines
Larger publishers with better brand recognition and stronger direct-to-consumer products are more insulated from declines in traditional search traffic.
Unilever considers separation of its food assets, Bloomberg News reports
Unilever is in the early stages of weighing a separation of its food assets as the consumer goods maker plans to streamline its business, Bloomberg News reported on Tuesday, citing people familiar with the matter.
Domestic Politics May Impede Vietnam’s Growing Relationship With the U.S.
Vietnam is performing a balancing act, but it’s unclear how long it can keep the plates spinning. On March 16, Vietnam held its first ever “3+3” summit with China, a meeting that featured both...
The 2026 Lollapalooza lineup just dropped: Everything to know about dates, headliners, tickets and more
The annual four-day music festival officially returns to Grant Park in Chicago, Illinois July 30-Aug. 2 with over 150 musicians including this year's headliners Charli XCX, Tate McRae, Lorde, Olivia Dean, John Summit, Jennie, The Smashing Pumpkins and The xx.
President of Summa Health Medical Group pleads guilty in revenge porn case, avoids prison
The President of Summa Health Medical Group pleaded guilty to one count of nonconsensual dissemination of private sexual images in connection with a revenge porn investigation.
Magic mushroom-infused products appear in Colorado gas stations – what public health officials want consumers to know
Hallucinogenic chocolate bars were removed from six Denver-area gas stations.
Maine Democratic Senate primary grows increasingly bitter as party vies to unseat Susan Collins in key race
A bitter Democratic primary is unfolding in Maine as Gov. Janet Mills and Graham Platner battle for the chance to challenge GOP Sen. Susan Collins — pitting a governor with a long political resume against an anti-establishment oyster farmer.
Kern County could see record heat as Bakersfield nears 95 in mid-March, NWS says
It may feel like summer in Kern County, but it is only the middle of March — and temperatures could reach the mid-90s, raising concerns about record heat and th
Alibaba shakeup hints at an AI business model
The $325 bln group is separating its AI initiatives from its cloud computing unit. It’s a nod to a craze for digital agents like OpenClaw and willingness of consumers to pay for these standalone services. Monetising AI will remain daunting but the rejig makes sense.
‘Room for improvement’: EU sports czar warns FIFA over leadership before World Cup
Glenn Micallef tells POLITICO that Gianni Infantino has not provided safety assurances for European fans heading to the U.S. this summer.
Fishing shop says business is unusually good for March, but warm winter could hurt them down the road
With temperatures expected to push record highs for March later this week, typically summer-oriented businesses are experiencing an early-season boost in success. While things are looking good in t…
Montage Health donates $15 million to expand nursing education at CSUMB
Montage Health is donating $15 million to Cal State Monterey Bay to address the nursing shortage in Monterey County by expanding nursing education programs.
Consumer Reports: Preventing kids' sports injuries
Consumer Reports has important advice for parents on how to help prevent common and often avoidable sports injuries.
Gen Z Loves This Old-School Way of Shopping — But With a Twist: ‘Lines Out the Door’
Successful brands are meeting their young consumers where they want to be.
The Walt Disney Company Sets Leadership Team for Expanded Disney Entertainment Segment
BURBANK, Calif., March 16, 2026--Dana Walden, incoming president and chief creative officer of The Walt Disney Company (NYSE: DIS), today announced the new leadership structure for Disney Entertainment, bringing together the company’s streaming, film, and television businesses along with its growing games and digital entertainment division. Consumers today want to engage with Disney’s storytelling and characters in a multitude of ways – whether on Disney+, in theaters, or through the digital gam
Honda cancels 3 planned EV models for US
Honda shifts U.S. strategy from electric vehicles to hybrids as consumer demand weakens, canceling three planned EV models including Honda 0 Series lineup.
CBA Launches Small Business Curriculum as Part of Advanced Education Programs
WASHINGTON, D.C. – The Consumer Bankers Association (CBA) recently launched the newest addition to its banking education curriculum, Talking Business with Small Business (TBWSB) – a curriculum focused on small business lending – as part of its Advanced Education programs. The curriculum leverages a tabletop simulation for branch managers to better understand…
Epic Southern California heat wave poses deadly health threat
"This is effectively a full-on summer heatwave in March," a climate scientist wrote on X.
Chateau Ste. Michelle announces 2026 summer concert lineup
A big-name country star scales down for an underplay at the beloved Woodinville winery this summer.
Governor’s Compact on Entrepreneurship
At the NGA 2026 Winter Meeting, Governor Kevin Stitt invited governors to join him in signing on to a compact, which sets out a variety of ways governors can make entrepreneurship a priority their states. The compact will culminate at NGA’s Summer Meeting in Oklahoma City, when Gov. Stitt will highlight governors’ actions to unleash […]
Thompson Scholars Program preparing future pre-health professionals for early success at UTC
The University of Tennessee at Chattanooga is offering incoming and transfer students an opportunity to strengthen their math and chemistry skills before the fall semester begins through the Thompson Scholars Program, a selective summer bridge experience designed for students pursuing professional health care careers.
New Edina sports bar from Nolo’s owners bets on a summer opener
General Sports Bar will open in the former Salut space in the 50th and France area.
Nearly $200M federal rural health grant in limbo in Idaho Legislature
Idaho lawmakers are debating how the state should spend hundreds of millions in federal funding this summer to improve rural health care.
How AI is reshaping healthcare and raising ethical questions
Can artificial intelligence reshape healthcare without deepening inequalities or outpacing the rules designed to govern it? Experts will debate the boundaries of Europe’s digital health future at Euronews Health Summit on 17 March in Brussels.
Deepfake Influencers Push Supplements Online
AI-generated figures are promoting wellness products to unsuspecting consumers
USA TODAY Sports projects Nebraska to play this Summit League team
Today is the day that Nebraska will learn its opponent for the opening round of the NCAA Tournament.
The founder of $100M brand Late July and Nixie started selling $1 cookies at 12 and learned the snack trade from the founder of Cape Cod chips—her dad
Nicole Bernard Dawes, the founder of Late July and Nixie, got her start in business selling $1 cookies at local delis—the lessons she learned from the $500 summer hustle led to multimillion-dollar success.
Is Academy Sports and Outdoors, Inc. (ASO) A Good Stock To Buy?
Is ASO a good stock to buy? We came across a bullish thesis on Academy Sports and Outdoors, Inc. on Valueinvestorsclub.com by andreas947. In this article, we will summarize the bulls’ thesis on ASO. Academy Sports and Outdoors, Inc.’s share was trading at $55.50 as of March 12th. ASO’s trailing and forward P/E were 10.20 and 8.51 respectively […]
Summit High School science teacher wins award
The National Association of Geoscience Teachers announced in a recent news release that Summit High School teacher Mary Slack has been awarded the Outstanding Earth Science Teacher Award for the Rocky Mountain section. This award...
10+ New Features Coming in iOS 27
We're only three months away from Apple's WWDC 2026 event, which will see the company unveil iOS 27. With the fully revamped version of Siri possibly delayed until September, iOS 27 is shaping up to be the update we wanted iOS 26 to be. There will be new Apple Intelligence features, updates for the iPhone Fold, and more, with the latest rumors summarized below.
Leaked audio appears to reveal Rebel Wilson's PR team plotting smear campaign against 'The Deb' producer
In court filings, Rebel Wilson's PR team is being accused by Ghost’s attorneys of plotting a smear campaign amid an ongoing legal battle connected to the actress' directorial debut, 'The Deb.'
Direct-to-consumer health gets a jolt
DTC plays are being revitalized by investor demands for credible margins.
Review: 'Project Hail Mary' launches summer season with heart, humor and a whole lot of science
Once in a while a movie comes along, that reminds us why the big screen still matters.
2nd annual mental health summit focuses on support, resources for first responders
The mental health of first responders is getting special attention in western North Carolina during a three-day summit in Buncombe County.
Maine’s wild blueberries deliver more than tradition. Research proves they support health.
Wild blueberries — the iconic Maine crop dotting hillsides, decorating sweatshirts and adding personality to local menus — is more than a cultural symbol. Over 20 years of preclinical and clinical studies suggest that regularly consuming wild blueberries supports gut and heart health and may reduce risk factors associated with…
Virtual Health Equity Summit
The Health Access and Strategic Innovation (HASI) department welcomes you to join us for the virtual Health Equity Summit. The event is open to everyone and registration is free.
EXCLUSIVE: Woodhaven’s Neir’s Tavern targeted in attempted burglary, owner announces ‘Small Business Safety Summit’
On Wednesday, March 4, a security breach was captured on surveillance footage, showing four masked individuals attempting to break into Neir’s Tavern, located
Fed's favored inflation gauge remained stubbornly high in January as consumer price pressures persist
The Commerce Department on Friday released the January 2026 PCE inflation report, which showed the Federal Reserve's preferred inflation gauge remained stubbornly high for consumers.
Pirates Prospect Update: Hunter Barco primed to have big year
The Pirates are presumably still searching for a fifth starting pitcher.
Higher health insurance premiums spark interest in religious cost-share ministries
Enrollment in health care sharing ministries is on the rise in Florida, but research shows they have fewer consumer protections.
How Golden Entertainment (GDEN) Narrative Is Shifting As Analysts Reassess Risk And Reward
Golden Entertainment’s latest analyst update keeps the fair value target steady at $30.50, even as assumptions behind that figure shift. Bullish and bearish voices are now reading the same unchanged headline number in very different ways, with some seeing headroom for upside and others treating it as a signal that the risk or reward balance has cooled. As you read on, you will see how these views are forming and how you can track the story as it continues to evolve. Analyst Price Targets...
Whittaker: Get money out of politics
Michigan voters face rising utility bills and fees as DTE and Consumers Energy donate hundreds of thousands to state legislators.
Japan PM’s health sparks concern before Trump summit
Japan’s Prime Minister Sanae Takaichi appeared unwell at a budget committee session on Thursday, which sparked concerns over her health. This comes less than a week before her meeting with President Trump in Washington. On Friday, Japan’s government said she has recovered and returned to official duties. CNN’s Hanako Montgomery reports.