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Scientists Discovered an Amazing Practical Use For The World's Leftover Coffee Grounds

We shouldn't throw it out.

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Oct 25 • 4:00 PM EDT • Science • sciencealert.com
Scientists Discovered an Amazing Practical Use For The World's Leftover Coffee Grounds

We shouldn't throw it out.

yahoo.com logo
Oct 25 • 4:00 PM EDT • Science • yahoo.com
NH candidates for governor, U.S. Senate, Congress clash over...

At a Manchester forum, New Hampshire candidates clashed over housing, energy, healthcare and other costs as affordability emerged as voters’ central concern. ...

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Oct 25 • 4:00 PM EDT • Politics • unionleader.com
French and Italian Retailers Tally Losses Ahead of Holiday Season

Retailers in France and Italy face financial losses and security concerns as protests disrupt business ahead of the holiday shopping season.

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Oct 25 • 3:57 PM EDT • Business • wwd.com
Ex-Spur Jeremy Sochan becomes a Legend

The Dallas Legends used the top pick in Saturday's G League draft on Sochan, who will look to salvage an NBA career that has not gone as expected for the former lottery selection.

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Oct 25 • 3:53 PM EDT • Sports • sports.yahoo.com
Photo: Jude Bellingham’s head-turning new boots for Barcelona showdown

Real Madrid star Jude Bellingham has on Sunday evening provided a look at the head-turning footwear that he is set to make use of in El Clásico.The latest edition of Spanish football’s most bitter ...

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Oct 25 • 3:45 PM EDT • Sports • sports.yahoo.com
Michigan basketball gets reality check in exhibition loss vs Houston

Michigan writer Tony Garcia offers three observations from the Wolverines' 83-66 loss to Houston in its final exhibition.

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Oct 25 • 3:42 PM EDT • Sports • sports.yahoo.com
Primark's Business Doesn't Make Sense

In a world where fast fashion giants like Shein, Zara, and H&M drop thousands of new styles every day — and rake in billions through e-commerce — Primark is doing the unthinkable: thriving with zero online shopping. So what gives?*Want to Know the 5 Trends Changing Modern Retail? Find Out Here:* 🔗 https://clickhubspot.com/d13ac2In this video, we take you inside Primark’s weirdly brilliant business model — a model that’s stuck in the past on purpose. From warehouse optimization and floor-ready freight shipments to why the pandemic didn’t push them online, we unpack how this low-cost retail giant has managed to defy digital norms… and make it work.This isn’t just about one brand. It’s a story about modern retail expectations — and what it actually takes to meet (or reject) them.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot

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Oct 25 • 3:31 PM EDT • Business • finance.yahoo.com
Rep. Carbajal Meets with Cottage Health’s Head Honchos in Santa Barbara as They Brace for ‘Big Beautiful Bill’ Impacts

Trump’s bill expected to leave close to 40,000 Central Coast residents without health coverage, another 37,000 with higher premiums, and a roughly $40 million initial impact on Cottage.

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Oct 25 • 3:30 PM EDT • Health • independent.com
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Packers RG Kevin Zeitler inactive, with Aaron Banks active
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Oct 25 • 3:30 PM EDT • Sports • sports.yahoo.com
☹️ Negative (-13%)
Utah business, government leaders deepen connections in Ireland

Utah Gov. Spencer Cox met with Irish Prime Minister Micheál Martin on Wednesday amid a trade mission organized by World Trade Center Utah.

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Oct 25 • 3:30 PM EDT • Business • ksl.com
Des Moines bishop says White House 'exploited' visit for politics

Bishop William Joensen was one of several invited to the White House for a private meeting they say is being used for "partisan political purposes."

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Oct 25 • 3:28 PM EDT • Politics • desmoinesregister.com
Science 4 Everyone: How does sod and tall fescue work?

Science teacher and Storm Team4 Meteorologist Ryan Miller explains how to use sod in your yard to prepare for cooler weather.

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Oct 25 • 3:27 PM EDT • Science • nbcwashington.com
Cardinals vs. Broncos live updates, analysis, highlights, scoring

We have live updates of the Cardinals-Broncos game in Week 7. Keep up with pregame, in-game and postgame coverage.

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Oct 25 • 3:18 PM EDT • Sports • sports.yahoo.com
Retailers in Paris React to Protests [PHOTOS]

Retailers Assess Cost of Lost Business After Second Round of Protests

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Oct 25 • 3:08 PM EDT • Business • wwd.com
‘Masterplan’: Too lightweight to make an impact

Pretty faces can’t overcome ho-hum plotting

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Oct 25 • 3:08 PM EDT • Entertainment • davisenterprise.com
USC Drops Out of AP Top 25 Poll After Wisconsin Loss, UCLA Rises Again

Both the USC Trojans and the UCLA Bruins had their rankings in the Associated Press Top 25 poll following their results from Saturday. View this post on Instagram A post shared by LA Sports Report (@lasportsreport) What Happened to USC’s Ranking? Following their loss to Wisconsin on Saturday, USC dropped out of the Top 25. […] The post USC Drops Out of AP Top 25 Poll After Wisconsin Loss, UCLA Rises Again appeared first on LA Sports Report.

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Oct 25 • 3:07 PM EDT • Sports • sports.yahoo.com
Sky Sports share rumours of unhappy Leeds United star live on air vs Sunderland

Daniel Farke looking unimpressed as Leeds United take on Sunderland at Stadium of Light on 25 October

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Oct 25 • 3:05 PM EDT • Sports • sports.yahoo.com
Dodgers’ De Paula Faces Key Defensive Test

Josue De Paula impressed the Los Angeles Dodgers with his bat during his major-league debut. Can he do the same with his defense?

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Oct 25 • 3:04 PM EDT • Sports • sports.yahoo.com
TCU to offer lifestyle medicine certification for doctor of occupational therapy students

Lifestyle medicine focuses on helping patients change their lifestyles in order to prevent, treat and reverse chronic disease.

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Oct 25 • 3:00 PM EDT • Health • fortworthreport.org
Halloween evolved as a Frankenstein of cultural celebrations

The holiday has origins in Celtic, Roman and Catholic festivals and feasts, and mixed with other traditions as it spread.

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Oct 25 • 3:00 PM EDT • Entertainment • theshorthorn.com
Asher Grunis steps down from leading Submarine Affair commission due to health concerns

Supreme Court President Isaac Amit appointed retired Supreme Court justice Zvi Zylbertal to replace Grunis and lead the commission on Sunday.

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Oct 25 • 2:58 PM EDT • Health • jpost.com
☹️ Negative (-4%)
🚨 Barcelona & Real Madrid name XIs for El Clásico

Barcelona and Real Madrid face off in El Clásico this evening. Hansi Flick's Barcelona top La Liga this season after winning all nine matches.Real Madrid will hope for improvements this evening as L...

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Oct 25 • 2:54 PM EDT • Sports • sports.yahoo.com
Nets' Second-Year G Dëmin Bounces Back Against Cavaliers

The Brooklyn Nets got a much-better performance from second-year BYU product Egor Dëmin against the Cleveland Cavaliers. With Mikel Brown Jr. on a minutes restriction, Dëmin needs to play a big role.

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Oct 25 • 2:49 PM EDT • Sports • sports.yahoo.com
Who's running to be Oklahoma's next Commissioner of Labor?

Republican Kevin West, Libertarian Mike Hall and Democrat Kevin Dawson will face off in November to be the next Commissioner of Labor.

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Oct 25 • 2:46 PM EDT • Politics • kgou.org
Trump’s Election Attacks Enter New Pre-emptive Phase

A lawsuit by the Justice Department challenging a potential narrow loss by the GOP Senate incumbent in Alaska reflects a new tactic by the president to try to shape the election results.

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Oct 25 • 2:42 PM EDT • Politics • nytimes.com
“Business as usual” – PSG coach refuses to give his players an excuse after triple blow

PSG are missing some important players, but that’s not an excuse says manager Luis Enrique, who still expects the best.If you enjoy PSG Talk coverage and want to see more of it, add us as a preferre...

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Oct 25 • 2:42 PM EDT • Business • sports.yahoo.com
Heidi Klum frightens fans, teases Halloween costume with bizarre close-up of strange prosthetic

The Queen of Halloween herself Heidi Klum is offering fans a first look at this year’s Halloween costume. As usual, it involves some pretty bizarre prosthetics.

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Oct 25 • 2:37 PM EDT • Entertainment • ew.com
Three Premier League talking points

Michael Carrick was pushed to the brink of the sack by Manchester United's latest debacle on Sunday.AFP Sport looks at three talking points from the weekend's action: Walls closing in on Carrick Michael Carrick's future as Manchester United boss was already hanging by a thread before Bournemouth inflicted what is likely to be a brutal last act for the former England midfielder at Old Trafford.

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Oct 25 • 2:36 PM EDT • Sports • sports.yahoo.com
49ers lead at halftime despite offense struggling without Christian McCaffrey
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Oct 25 • 2:30 PM EDT • Sports • sports.yahoo.com
Buccaneers blowing out Panthers with 33-6 halftime lead
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Oct 25 • 2:27 PM EDT • Sports • sports.yahoo.com
Top Japanese Prospect Has His Eyes on the Dodgers

The Los Angeles Dodgers are the industry favorite to sign the best prospect in Japan, 18-year old pitcher Shoki Oda.

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Oct 25 • 2:26 PM EDT • Sports • sports.yahoo.com
The Future of IBD Treatment: 4 Promising Therapies to Know About

New treatments are in development for inflammatory bowel diseases like Crohn’s disease and ulcerative colitis. Find out what experts say you should know.

health.yahoo.com logo
Oct 25 • 2:21 PM EDT • Health • health.yahoo.com
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race

Blanche told CNN's “State of the Union” that President Donald Trump, who said Friday that he was "the one that said do it,” is not trying to overturn state election results “in any way, shape or form” on the cusp of the Nov. 3 election.

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Oct 25 • 2:19 PM EDT • Politics • pbs.org
Phantom Blade Zero Preload Time & Date Revealed; Clocks in at 145 GB as PC Requirements Listed

While a lot of PS5 gamers are eagerly awaiting Phantom Blade Zero, some might not know that the game is also releasing day and date on PC. If you're one…

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Oct 25 • 2:15 PM EDT • Technology • mp1st.com
Nintendo reveals why you don't actually fight Bowser in Super Mario Bros. 1

Nintendo’s Shigeru Miyamoto has shared some insight into why players don’t actually fight Bowser in the original Super Mario Bros. Miyamoto was present at a press conference at the end of the week to celebrate him becoming the first developer to win Japan’s Order of Culture award. During the event, he was asked to share behind-the-scenes stories about the making...

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Oct 25 • 2:15 PM EDT • Technology • nintendoeverything.com
Binaytara Implementation Science Research Awards 2027 - Oncology News, Insights, Stories by OncoDaily

The Binaytara Implementation Science Research Awards 2027 provide up to $25,000 per project to support early-career investigators improving how evidence-based

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Oct 25 • 2:15 PM EDT • Science • oncodaily.com
Windows 11 is apparently so bad that XBOX would rather cancel hardware than be forced to use the OS

A reported clash between Microsoft's XBOX and Windows teams suggests Windows 11's desktop may no longer be the foundation for Project Helix.

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Oct 25 • 2:14 PM EDT • Technology • windowscentral.com
Ramaswamy built his political career in NH. It's faltering in Ohio.

Many New Englanders remember Ramaswamy from his mad-dash presidential campaign in New Hampshire. Will his political career survive a tumultuous run for Ohio governor?

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Oct 25 • 2:13 PM EDT • Politics • bostonglobe.com
Trump on high gas prices: 'We're making a freaking fortune"

Americans, meanwhile, are paying record prices at the pump, according to AAA.

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Oct 25 • 2:04 PM EDT • Business • businessinsider.com
Inside 26-year-old’s club for million-dollar Chattanooga business owners

At 2nd American Restaurant on Thursday night, around 85 entrepreneurs who have scaled their businesses to at least $1 million in annual revenue sat to a family-style meal of beef cheek roast, airline chicken and the restaurant's signature bowl of mashed potatoes.

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Oct 25 • 2:01 PM EDT • Business • timesfreepress.com
Vegas gives Ole Miss double digit spread against visiting Auburn

Despite the loss to Texas, Ole Miss is heavily favored against Auburn

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Oct 25 • 2:00 PM EDT • Sports • sports.yahoo.com
Candidates differ on taxes, schools, health care

House hopefuls outline priorities ahead of election

sanduskyregister.com logo
Oct 25 • 2:00 PM EDT • Health • sanduskyregister.com
😐 Neutral (7%)
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45%
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Navigating D1 pressure: how student-athletes balance their mental health

Mental health affects everyone, including athletes who have a really good way of hiding it. Research shows that mental health issues affect roughly 39-44% of Division I athletes. Behind game day, good game performance, and navigating life in college, D1 athletes are constantly trying to balance high expectations with their own well-being. It’s not...

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Oct 25 • 1:59 PM EDT • Health • nmsuroundup.com
Blanche defends DOJ lawsuit blocking Alaska Senate results if Republican loses

Attorney General Todd Blanche defended the Justice Department's suit over Alaska's Senate race in an interview on CNN.

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Oct 25 • 1:50 PM EDT • Politics • npr.org
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Scientists Develop a Clever New Way To Kill Cancer Cells From the Inside

Scientists have developed an experimental strategy that exploits a chemical byproduct of cancer cells to produce anticancer drugs directly inside them. Scientists in Japan have developed an experimental method that uses a chemical produced by cancer cells to manufacture anticancer drugs directly inside them. The approach relies on carbon monoxide, a toxic gas that certain

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Oct 25 • 1:45 PM EDT • Science • scitechdaily.com
Unpatched Tailscale SSH Flaws Could Let a Hacked Device Reach Root on Other Servers

Unpatched Tailscale SSH flaws could let attackers gain root on permitted servers from a compromised device when port forwarding is enabled.

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Oct 25 • 1:44 PM EDT • Technology • thehackernews.com
Professor Katherine McNeill Inducted Into Massachusetts Science Educators Hall of Fame

Katherine L. McNeill was inducted into the Massachusetts Science Educators Hall of Fame on Friday in recognition of her two decades of work in science education.

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Oct 25 • 1:33 PM EDT • Science • bcheights.com
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Google's privacy policy now has a loophole for using your Gmail and Photos data in ads

The change sits in Google's updated privacy policy, which took effect on October 16 and was first spotted by Android Authority. The policy has long said, "We...

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Oct 25 • 1:33 PM EDT • Technology • techspot.com
Projections for Cleveland Guardians’ Arbitration Eligible Players

The Cleveland Guardians have several key players arbitration-eligible this offseason.

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Oct 25 • 1:30 PM EDT • Sports • sports.yahoo.com
J.J. McCarthy, Giants take 7-3 lead on Texans
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Oct 25 • 1:29 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Elon Musk’s Grok Releases First AI-Generated “Odyssey” Episode

Months after Elon Musk promised that Grok Imagine would make an entirely AI “Odyssey” film, the tech mogul has partially followed through.

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Oct 25 • 1:22 PM EDT • Technology • variety.com
Scientists Discover How Excess RNA Can Disrupt the Energy Supply Inside Cells

Scientists at Texas A&M University discovered that excess RNA can interfere with the machinery cells use to produce energy, even without triggering certain immune defenses. The findings reveal an unex...

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Oct 25 • 1:19 PM EDT • Science • yahoo.com
New Trump housing order targets mortgage and title insurers

A White House plan to pull private mortgage insurance off loans sooner, and to let refinancing borrowers skip the lender's title policy, affects two insurance lines that say they already help keep costs down

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Oct 25 • 1:09 PM EDT • Business • insurancebusinessmag.com
How Argentina’s Folk Sounds Are Shaping a Generation’s Politics and National Pride

Milo J, Cazzu, and more stars are embracing music and traditions of the Argentine countryside, staving off pop homogenization and sharing their history with the world

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Oct 25 • 1:09 PM EDT • Politics • yahoo.com
China Star Entertainment (SEHK:326) Stock Looks Richly Priced As Its 8.6x Run Continues

China Star Entertainment has logged very strong multi year share gains, so the key issue now is whether the current price can be supported by the value of assets on its balance sheet. For anyone looking at the stock today, the immediate question is how that share price lines up against its book value. Over the past 3 years the stock has returned about 8.6x. This puts a lot of weight on whether the underlying equity in the business justifies this kind of move when you compare it with the...

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Oct 25 • 1:06 PM EDT • Entertainment • finance.yahoo.com
Business People: Evereve names industry vet Sarah Clary to advise on creative

RETAIL Evereve, an Edina-based women’s fashion retailer, announced it has named Sarah Clary as advisory chief creative officer. Clary previously has led creative direction campaigns and brand strategy for Hill House Home, Veronica…

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Oct 25 • 1:01 PM EDT • Business • twincities.com
The Making Of: Addams Family Values, Ocean Software's Attempt to Mix Hollywood & the Legend of Zelda

"Management didn't really understand development or the creative process"

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Oct 25 • 1:00 PM EDT • Technology • timeextension.com
Police: Lancaster County health care worker assaulted

Incident occurred at WellSpan Hospital in Ephrata Borough, according to police.

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Oct 25 • 12:42 PM EDT • Health • wgal.com
Jaylen Warren and the Steelers run over the Saints in Paris
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Oct 25 • 12:35 PM EDT • Sports • sports.yahoo.com
Orlando Science Center hosts Halloween party

Adults can enjoy an open bar, laser shows, and more at the Orlando Science Center's Halloween After Dark on October 31.

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Oct 25 • 12:32 PM EDT • Science • wftv.com
Warriors honor Bay Area sports reporter Michael Wagaman

After Michael Wagaman passed away in early August, Dallas Braden took time to tribute him during his call of the Athletics’ game on NBC Sports Bay Area and California. Wagaman had covered Bay Area sports teams since 1996, including for the Associated Press, and freelanced for NBC Sports Bay Area and California at the time…

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Oct 25 • 12:30 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
11 Cool Mini-Gadgets You May Not Realize Exist

You probably weren’t looking for a remote-control paper plane or a $600 calculator. Fair enough. They exist anyway, and they’re weirdly hard to ignore.

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Oct 25 • 12:30 PM EDT • Technology • slashgear.com
Sunday Puzzle: BRB

NPR's Ayesha Rascoe plays the puzzle along with Weekend Edition Puzzlemaster Will Shortz and WUOT listener Jordan Bogdan of Oak Ridge, Tennessee.

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Oct 25 • 12:30 PM EDT • Entertainment • kgou.org
😐 Neutral (9%)
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75%
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25%
Browns injury update: Is Denzel Ward playing against the Titans?

The Browns will enjoy the presence of their top cornerback in Week 7.

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Oct 25 • 12:22 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
Opposition leader María Machado returns to Venezuela

Machado had left the country just a month before the US government seized Venezuelan President Nicolás Maduro.

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Oct 25 • 12:21 PM EDT • Politics • bbc.com
Kansas at Duke: Exhibition OGT

Kansas basketball hopes to follow the football team with a win today. Yeah, this game doesn’t count, but any time you’re playing Duke you want to win. Plus, this exhibition game is a big enough deal that ESPN is broadcasting it live (probably because they know everyone else will be watching football. I’m probably going […]

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Oct 25 • 12:21 PM EDT • Sports • sports.yahoo.com
😐 Neutral (6%)
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One Of Steven Spielberg's Biggest Box Office Flops Is An Underrated Disney Movie

Steven Spielberg is one of the most prolific directors to still be working, and he's known for absolutely stunning films, but not every movie can be a hit.

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Oct 25 • 12:17 PM EDT • Entertainment • yahoo.com
Photographer and medical professionals connect science and art during panel discussion

In 2020, the world was put on hold because COVID-19 began claiming the lives of people all over the globe. When a vaccination for the illness was finally made public in 2021, being vaccinated became highly politicized. Instead of focusing on the emotional reactions that people had toward the vaccine, artist Linda Alterwitz was more...

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Oct 25 • 12:14 PM EDT • Science • thesunflower.com
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Kings' Veterans Praise Rookie Acuff After 33-Point Showing

The Sacramento Kings are yet to get a win, but Darius Acuff Jr. looks like the high-octane guard that the franchise so desperately needs. Coming off a 33-point outburst, how will Acuff play against the Memphis Grizzlies?

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Oct 25 • 12:13 PM EDT • Sports • sports.yahoo.com
Lycia Lands a $317M IPO for Inflammation Drugs Based on Nobel Prize-Winning Science

Lycia Therapeutics’ protein-degrading drugs are based on the research of Carolyn Bertozzi, a Stanford chemistry professor and Nobel laureate. Lycia’s lead drug candidate is in development for food allergy, where it could compete against the blockbuster Roche drug Xolair.

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Oct 25 • 12:13 PM EDT • Science • medcitynews.com
Memorial Health celebrates staff with trunk-or-treat

Memorial Health went all out for its annual trunk-or-treat event, celebrating team members and their families.

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Oct 25 • 12:13 PM EDT • Health • kswo.com
😐 Neutral (9%)
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Bloomington business continues to blossom

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Oct 25 • 12:11 PM EDT • Business • insideindianabusiness.com
😐 Neutral (0%)
3 comments | Progressive Democrats are closely watching four Senate...

Progressive Democrats are closely watching four Senate races in the upcoming midterm elections. Our politics reporter Kellen Browning explains why.

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Oct 25 • 12:07 PM EDT • Politics • facebook.com
😐 Neutral (0%)
Buccaneers vs. Panthers Week 7 inactives: Baker Mayfield returns

The Tampa Bay Buccaneers are set to take on the Carolina Panthers Sunday afternoon in a crucial NFC South matchup at Bank of America Stadium in Charlotte. Tampa Bay received some encouraging news ahead of kickoff as quarterback Baker Mayfield is officially active and will start after missing the previous three games with a dislocated […]

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Oct 25 • 12:05 PM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
In West Maui, Democrat-turned-Republican defends House seat against Lahaina Strong organizer, local business advocate

Incumbent Rep. Elle Cochran, Green Party candidate Pā’ele Kiakona and Democratic nominee Sne Patel are battling to represent West Maui at a pivotal time in the fire recovery.

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Oct 25 • 12:01 PM EDT • Business • mauinow.com
Data center boom sparks massive power line fights hundreds of miles away

In Cat Kemmerling’s dream, she and her husband Rob are sitting in their pickup truck on a cliff on their West Virginia farm, overlooking the Shenandoah River. The truck is falling backwards over the edge, into the abyss below.

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Oct 25 • 12:00 PM EDT • Politics • cnn.com
How the conservative Supreme Court has rewritten the rules for the midterms

Voters will pick the winners of next month’s midterm elections, but it is the conservative Supreme Court that has set the rules.

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Oct 25 • 12:00 PM EDT • Politics • cnn.com
John Sununu is running on his family’s legacy in New Hampshire. His brother is staying on the sidelines

The campaign signs across New Hampshire read “Sununu” in block letters.

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Oct 25 • 12:00 PM EDT • Politics • cnn.com
"It never was entertainment to us, ever. It was always something with a lot more importance and meaning." U2 reveal the unbroken promise that they made to one another as schoolboys in Ireland 50 years ago

"Music is not a matter of life and death, it’s something much more serious than that"

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Oct 25 • 12:00 PM EDT • Entertainment • loudersound.com
Americans have a grief problem we still call a mental health problem

OPINION — Americans have become much better at talking about mental health. We have learned words such as trauma, post-traumatic stress disorder, depression, anxiety, burnout, compassion fatigue and moral injury. That vocabulary matters.

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Oct 25 • 12:00 PM EDT • Health • yourvalley.net
Trick-or-treaters descend on Callow Avenue for Calloween

Photos from Charleston Business District's annual Calloween event on Saturday, Oct. 24. ·

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Oct 25 • 11:57 AM EDT • Business • kitsapsun.com
RJW Logistics to open second Northwest Arkansas office

Chicago-based RJW Logistics Group, which has a Bentonville office, plans to open an additional Northwest Arkansas office amid client growth and to support demand for a new logistics program offered...

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Oct 25 • 11:55 AM EDT • Business • talkbusiness.net
2 political experts question Chicago Mayor Brandon Johnson's tax proposals for 2027 budget
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Oct 25 • 11:55 AM EDT • Politics • cbsnews.com
High-Signal Publisher
Liverpool 2, Brighton 0 – Match Recap: That Was Actually Fun

A look back at the key moments in Liverpool's great victory over Brighton in Premier League action.

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Oct 25 • 11:55 AM EDT • Sports • sports.yahoo.com
Obama and Trump wage one last battle for even more urgent stakes

Two decades ago, Barack Obama stormed battleground states rebuking a Republican president over a deeply unpopular war and an economy that was crushing working Americans.

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Oct 25 • 11:45 AM EDT • Politics • cnn.com
Chair of 'submarine affair' committee probing Netanyahu resigns due to health concerns

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Oct 25 • 11:42 AM EDT • Health • haaretz.com
How Braves should handle $42 million Jurickson Profar situation

This could be one solution for the Braves.

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Oct 25 • 11:36 AM EDT • Sports • sports.yahoo.com
How Nathan Fielder's cringe-comedy career led him to Elizabeth Holmes

Spoiler alert! We're discussing the themes and structure of the Elizabeth Holmes documentary "You Can See Everything" and touching on a surprising aspect of its second half, so turn away if you want to go in completely cold.

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Oct 25 • 11:34 AM EDT • Entertainment • thenewstribune.com
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Texas Tech Leads 'Bad' Week 8 for Big 12 Unbeatens

The Red Raiders’ playoff dreams hit a wall in Cincinnati as sloppy play and missed opportunities ended their unbeaten run. The Big 12 race is now more open than ever after surprising finishes elsewhere.

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Oct 25 • 11:28 AM EDT • Sports • sports.yahoo.com
Nonprofit organizes ‘silkies’ hike to support military members’ mental health

During the hike, participants wore military short-shorts known as “silkies” as part of the event’s tradition to foster connection.

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Oct 25 • 11:27 AM EDT • Health • wpxi.com
Nonprofit organizes ‘silkies’ hike to support military members’ mental health

Veterans, active military service members and community supporters recently gathered for a hike organized by a nonprofit dedicated to suicide prevention.

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Oct 25 • 11:27 AM EDT • Health • wpxi.com
Jennifer Hawks explains why she should be California's State Treasurer

Jennifer Hawks, a candidate for California state treasurer, shared her qualifications and vision for the office in an interview on California Politics 360.

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Oct 25 • 11:25 AM EDT • Politics • kcra.com
Who can buy California's voter rolls and why?

Chris Micheli, an adjunct professor at McGeorge School of Law and longtime lobbyist, explained who is able to buy the voter rolls and why in an interview on California Politics 360.

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Oct 25 • 11:25 AM EDT • Politics • kcra.com
Timeline of the Capitol Annex project

Ashley Zavala looked back at the decade-long process of building the new offices for the governor and state lawmakers.

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Oct 25 • 11:25 AM EDT • Politics • kcra.com
South Texas Health System (@stxhealthsystem)

1 likes, 1 comments - stxhealthsystem on October 25, 2026: "Exceptional Care Starts With You: Nurses play a vital role in every patient journey, providing the compassionate, skilled care that helps make South Texas Health System’s 12 facilities a trusted healthcare resource for communities across the Rio Grande Valley. If you're passionate about making a difference and delivering exceptional patient care, now is your opportunity to join the largest integrated healthcare network in the region. STHS is seeking dedicated and compassionate registered nurses to join its team at four acute care hospitals, a behavioral health hospital and seven freestanding emergency departments. Become part of a team committed to clinical excellence, collaboration and compassionate care. To view current openings and apply, visit the STHS careers page at the link in our bio.".

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Oct 25 • 11:18 AM EDT • Health • instagram.com
Apple Stores Reportedly Rolling Out New Anti-Theft System for iPhones

Bloomberg's Mark Gurman today reported that Apple is facing a growing problem where some people will buy iPhones or other products and either remove accessories from the box, open up the device and remove components, and/or remove the entire device, and then attempt to return the box hoping that the employee will not notice.

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Oct 25 • 11:18 AM EDT • Technology • macrumors.com
California election officials frustrated, rattled by DOJ demand to sequester 'noncitizen' ballots

The administration has insisted that immigrants voting is a major problem nationwide, when in fact it is quite rare, as even its own investigations have shown.

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Oct 25 • 11:17 AM EDT • Politics • pbs.org
Google's next TV gadget may do much more than stream

A reported hardware overhaul could bring Gemini further into the living room.

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Oct 25 • 11:17 AM EDT • Technology • thestreet.com