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Casey Affleck ‘hasn’t’ heard from Christopher Nolan after asking for 'Tenet' explanation
More Than a Trim: Rethinking Hoof Health
Good hoof health takes more than a skilled trimmer. Jayden Palmer says the strongest dairy programs combine routine maintenance, good data, ongoing training and a team that understands what it is trying to accomplish.
This Virus Stole a Human Gene and Won’t Let Go of It
Scientists have found a human gene lurking in a virus that causes skin infections. It may be using our own DNA to infect us.
Man shot to death in Hyde Park business Saturday afternoon
The Boston Police Department is asking the public to provide any information to help solve this incident.
Infinity Song Is Done Asking for Permission
Infinity Song discusses sibling harmony, self-belief, a bold new album and creating communal escape through live music.
Kerecis Reimagines Fish-Skin for Deep Wounds with Launch of Compact
ARLINGTON, Virginia & REYKJAVIK, Iceland--(BUSINESS WIRE)--Sep 28, 2026--
Casey Affleck ‘hasn’t’ heard from Christopher Nolan after asking for “Tenet ”explanation
The actor called Nolan for insight into the film amid an argument with his son.
Seedy K’s Pigskin Palaver: Mediocrity, Bon Mots & Bad Woofs +++
Culling the landscape of college football. How Many Syllables Kamario? Couldn’t help myself. It’s an obscure reference to a line in the cult movie classic, “Putney Swope.” I could have titled this “More Cowbell” but I wanted to be subtler than that. Anyhow the Mississippi State Flavor of the Month QB — last name Taylor — […]
Google is officially killing Gemini Gems
The Gems manager in Gemini is now showing a banner officially announcing that Gems will be migrated to Skills starting November 17.
Call of Duty: Warzone will soon make it possible to toggle all those silly skins off, something no one thought could ever happen
The Modern Warfare 4 era of Call of Duty: Warzone begins with the game's first season, and it's introducing a feature fans have long been asking for.
Missouri doesn't require asking pregnant patients about their mental health. New moms keep dying
Asking the right questions is just the first step. Actually getting support, especially for moms in rural Missouri, is where providers say things get even harder.
Zidane urges players to embrace challenge of playing for France
France head coach Zinedine Zidane called on his players to relish playing for the national team as his squad went through its final preparations without injured skipper Kylian Mbappé for Monday night's Nation's League tie against Belgium in Brussels.
Health Tech Keeps Choosing Violence
Last week was an absolute dump of health tech litigation mayhem, with enough new filings to make my wife seriously question my bedtime reading. Here’s what’s inside: OpenEvidence v. Doximity: Doximity didn’t wait for the deadline. It wants OpenEvidence’s case thrown out entirely, and its motion adds some awkward details about vanished Slack data and borrowed NPIs. Plus, Epic v. Apple offers a look at what a normal discovery fight looks like. Texas v. Epic: Epic took another shot at the State’s antitrust pleadings, asking the court to make Texas spell out how its employment restrictions harm competition and why Texas law reaches a Wisconsin company’s noncompetes. Veeva v. Epic: The two Wisconsin law professors finally weighed in on whether a would-be employer can challenge someone else’s noncompete. Audacious Inquiry v. CRISP: Our sleepy patent case just evolved into a much more interesting form, with CRISP firing back with attempted monopolization and information blocking counterclaims. Cognizant v. Infosys: After weeks of emails and phone calls, I finally have Judge Starr’s sealed ruling on Infosys’s antitrust counterclaims. Some survived, offering clues about where the Epic (and other system of record) antitrust cases stand their best chance OpenEvidence v. Doximity
Seattle Mariners Manager Dan Wilson Out After Failed Season
Seattle Mariners manager Dan Wilson informed the team prior to Sunday’s game that he will not be returning as skipper for the 2027 season. The Mariners were preseason favorites to win the American League after Wilson’s squad advanced to game seven of the ALCS. The loss to the Toronto Blue Jays seems to be Wilson’s […] The post Seattle Mariners Manager Dan Wilson Out After Failed Season appeared first on HEAVY.
Misiorowski Guides Brewers to 103rd Win in Regular Season Finale
Cy Young favorite Jacob Misiorowski dominated St. Louis, securing Milwaukee’s 103rd victory and a first-round postseason bye as Brice Turang eclipsed the 100-RBI milestone in the finale.
Dirty hands, healthy life? What science really says may shock you - Futura-Sciences
The Rich Ecosystem Right at Our Fingertips For years, our skin was viewed as just a protective barrier. But in truth, it’s an ecosystem bursting with millions of invisible microorganisms: the cutaneous microbiome. It’s home to beneficial bacteria (like Staphylococcus epidermidis and Cutibacterium acnes), fungi (think Malassezia), viruses (such as...
Top Workplaces 2026: Skills vs. behavior: Find balance in hiring
Skills alone don’t guarantee success. Candidates might have plenty of technical know-how, but if they can’t collaborate, adapt or communicate effectively, they may not be the right fit.
Milwaukee Brewers vs. St. Louis Cardinals score, lineups, TV, updates
The Brewers close out the regular season against the Cardinals at American Family Field on Sunday, Sept. 27 with Jacob Misiorowski on the mound.
Here Are All Fortnite’s ‘Five Nights At Freddy’s’ Skins, Plus A Release Date
After years of requests, Five Nights at Freddy's is coming to Fortnite for its Fortnitemares event. Here are all the skins and its release date.
Gemini app replacing Gems with skills in November
In 2024, Google introduced Gems as “custom versions of Gemini.” The Gemini app will soon replace Gems with “skills.”
A final day at the Academy of Natural Sciences bring tears, nostalgia and disbelief
Inside the museum, a steady stream of visitors took photos, touched the skin of of a scaly anteater being circulated by educators, and guided toddlers in dinosaur costumes through exhibits.
Witcher Dev Reveals Why CD Projekt Red Doesn't Do Crossovers In Its Own Games
A Geralt-inspired skin is coming to Diablo 4, but don't expect Diablo characters in The Witcher 3 Remastered
How Harry Kane corrected Bayern Munich’s ‘serious mistake’ template
FC Bayern learned a hard lesson with the departure of Robert Lewandowski.
SNL skit mocks Dario Amodei's AI doomsday predictions
In a sketch, "Saturday Night Live" portrayed Dario Amodei as a bumbling megalomaniac struggling to explain why his own technology won't end the world.
Astronomers explain X-ray flares of pulsar in BP Crucis system
Astronomers used XRISM observations to explain powerful X-ray flares from the pulsar GX 301-2 in the BP Crucis binary system.
Uber CEO says ‘really demanding’ work culture includes expecting employees to answer emails over the weekend: ‘Don’t come here if you want to coast’
Uber boss Dara Khosrowshahi said the most important skill in life is working hard: “I’m not going to let anyone outwork me.”
Tripp Skipper: Barry Moore is going to Washington. Abdul El-Sayed shows what he’ll be fighting
And there may be no clearer illustration of the ideological fights awaiting Congressman Barry Moore in the United States Senate than Abdul El-Sayed.
Power & Politics: NJ Lt. Gov. Caldwell resigns following probe into allegations of sexual harassment, state ethics violations
Republican State Sen. Declan O'Scanlon, former State Rep. John Wisniewski and Republican Rep. Jefferson Van Drew join the show.
Power & Politics: NJ Lt. Gov. Caldwell resigns following probe into allegations of sexual harassment, state ethics violations
Republican State Sen. Declan O'Scanlon, former State Rep. John Wisniewski and Republican Rep. Jefferson Van Drew join the show.
Rogers Tries to Make El-Sayed’s Health Care Plan Scary
_Taylor, Michigan_HERE’S HOW YOU CAN TELL Mike Rogers is anxious to make up ground in the Michigan Senate race: He held a press conference on health care last weekend. Health care is usually a rough issue for Republicans, because voters associate the GOP with attacking cherished programs like Medicare and Medicaid that Democrats have historically supported. It’s a particularly difficult issue in this campaign, because a few months ago Donald Trump and the Republicans refused to extend temporary financial assistance in the Affordable Care Act. As a result of that decision, more than 20 million Americans faced higher insurance prices this year. That’s not a policy choice you want to be defending at a time when voters frequently cite the cost of health care as a top concern. Throw in the fact that Democratic nominee Abdul El-Sayed can draw on his credibility as a doctor and former public health director in Detroit, and it might seem like Rogers’s best bet would be to avoid health care altogether. But Rogers had his reasons to spotlight health care last Saturday. And they became apparent a few minutes before he spoke, when members of his campaign staff There’s a lot happening. Too much, some days. We can’t promise to have all the answers. But we can promise to keep asking the questions, following the facts, and figuring things out alongside people who care about where this country is headed. Read with us. Learn with us. And when it matters, stand with us. Join the side you’re already on. Join Bulwark+
Gen Z improving typing skills amid rise of AI technology
Gen Zers are taking typing classes. You need a keyboard to use AI — and they're used to phones.
Inside Gophers coach P.J. Fleck’s ‘crazy’ moment after Washington win
SEATTLE — P.J. Fleck got a little carried away in the immediate on-field celebration after the Gophers’ 27-24 win over Washington on Saturday. Linebacker Maverick Baranowski had just sealed the win in the Big Ten opener with a final-play tackle on Huskies receiver Dezmen Roebuck at Husky Stadium. Roebuck’s cleat slid up into Baranowski’s helmet and bloodied his mouth. Fleck then hugged one of ...
‘It’s problematic’: Concern as Vogue World event sponsored by ‘skinny jabs’ maker
Partnership between Mounjaro maker Eli Lilly and fashion giant, suggests thinness is an aspiration says critics
‘It’s problematic’: Concern as Vogue World event sponsored by ‘skinny jabs’ maker
Partnership between Mounjaro maker Eli Lilly and fashion giant, suggests thinness is an aspiration says critics
Revolution’s win streak snapped in loss to Real Salt Lake
Sergi Solans scored two goals for RSL to beat the Revolution, snapping its own 13-game winless skid on Saturday.
Today’s NYT Strands Hints, Spangram, Answers: Sunday, September 27 (It’s Skin Deep)
Looking for help with today's NYT Strands puzzle? Here's an extra hint to help you uncover the right words, as well as all of today's answers and Spangram.
Mount Dora restaurant says nearby roundabout construction is cutting off business
A Lake County restaurant owner said nearby construction is keeping customers away and cutting into sales; that's why he's asking for help.
Heard the news? Atlético seal deal for the 'new Dembélé'
Atlético have agreed the signings of Nigerians Taiwo Alao and Olasunkanmi Abbas, aged 18 and 17 respectively.A winger developed at Sporting Lagos in Nigeria, Alao is regarded as skillful, quick, and ...
‘AI can’t replace your doctor,’ expert warns amid rise in chatbot health advice
“You should never skip meeting with your health care professional,” Ogbru said. “You should not treat these platforms as giving advice.”
My husband and I skip holiday and birthday gifts; give surprises
We focus on date nights, trips, and surprises instead of birthday and holiday gifts. Once, he gave me diamond earrings on a random day "just because."
TST Best Bets: September 26, 2026
Two ranked Big Ten battles highlight Saturday’s slate, led by No. 12 USC hosting No. 20 Oregon at the Coliseum. The Ducks have won four straight in the series, but the Trojans have a chance to end that skid while strengthening their place in the College Football Playoff race.No. 17 Iowa and No. 18 Michigan also put their undefeated records on the line in Ann Arbor. With both teams leaning on physical rushing attacks and two of the nation’s better defenses, points could be difficult to come by at
House Democrats plan vast oversight of Trump administration. Impeachment is an option
Rep. Jamie Raskin (D., Md.), who is in line to become the chairperson of the Judiciary Committee, characterized the issues involved as “gargantuan.”
Washington County Continues Commitment to Veteran Mental Health
Washington County Health and Human Services continues to strengthen its commitment to those who have served our nation by launching a free monthly Mental Health Skills Group designed specifically for …
Second-half strikes give Ballymena win over Ports
Second-half strikes from Finley Thorndike and Igor Rutkowski give Ballymena a 2-0 win over Portadown.
The Best Skill In ‘Control Resonant’ And Where To Find It
'Control Resonant' has many very fun skills, but one stands above the rest and you will want to get it as soon as possible.
Tyquan Thornton credits his hometown for his wide receiver skills
During Friday's press conference, Kansas City Chiefs wide receiver Tyquan Thornton credited his hometown for his wide receiver skills | @EdEastonJr
OpenAI report reveals the workplace skills AI can't automate as easily
OpenAI's latest data shows AI is automating coding fast, but human judgment, priorities, and decision-making still matter most.
Science Behind the Forecast: Don't like gloomy skies? Blame nimbostratus clouds
Every week WAVE 3 meteorologist Tawana Andrew breaks down what we know and what we don't about the climate and weather here in Louisville.
Amazon Canada has a Shark vacuum for 43% off, wrinkle-fighting skincare for under $15 & 25 more early October Prime Day deals to shop this weekend
Ready, set, save!
Overreliance on AI could replace 'social intelligence' in the workplace, protocol expert warns
Pamela Eyring warns that AI's convenience is eroding critical people skills, and businesses that fail to balance automation risk losing clients and money.
As the coding boom fades, computer science grads focus on AI skills in choppy job market
CS grad Jack Zemke sent hundreds of applications into the void, then landed an “AI evangelist” role after demoing a project. As AI reshapes entry-level hiring, schools pivot to AI tool training and new internships.
Vail Health will bring medical records under one digital roof across Eagle County and beyond
On Oct. 3, Vail Health will transition to a new electronic medical record system that will be easy for many locals to remember since it coincidentally shares the same name as a well-known ski pass....
Pulaski MTN-X to create temporary traffic impacts in Pulaski, Wythe, Bland and Giles Counties Saturday
Pulaski County Sports and Entertainment officials are reminding residents and motorists that the inaugural Pulaski MTN-X gravel bike race will take place Saturday, resulting in temporary traffic impacts on roads.
Record-breaking singer Ella Langley shuts down influencer who shouted at her in public asking for date
Langley currently reigns at No. 1 on the “Billboard” Hot 100 with “Choosin’ Texas,” which shattered Mariah Carey’s record for most weeks atop the chart.
Controversial sports commentator calls out struggling NFL team: ‘You look pathetic’
Skip Bayless criticized the Green Bay Packers after a home loss to the Atlanta Falcons, calling their play 'pathetic.'
Rob Gronkowski thought media criticism of his partying was ‘ridiculous’
Rob Gronkowski liked to party and have fun when he was an NFL player, but he still showed up ready to go on Sunday. Gronkowski joined The Dan Patrick Show Friday morning, where the NFL on Fox analyst was asked about the media criticism he endured because of his off-field antics as a player. Patrick…
Photos: Fall semester, soap carving and business built by grads
Happy Friday, Huskies! This week, students in Oakland held a new kind of student government election. Over in Boston, dive inside the Soap Carving Club’s growing popularity. And, graduates share the businesses they build through entreprenuership.
Quick hitters: O-line health, safety depth and Dan Campbell’s first days in Detroit with Glenn
Allen Park — Detroit Lions coach Dan Campbell and quarterbacks coach Mark Brunell met with the media on Friday. Here are the noteworthy items from those conversations. Healthier up front, banged up in the back It’s good news, bad news on the injury front. First, the offensive line is going to be far closer to full strength with starters Blake Miller (knee) and Christian Mahogany (hip) on track to return to the lineup. That provides stability the offense lacked against Buffalo, particularly at right tackle, where backup Larry Borom allowed 11 quarterback pressures and committed a trio of penalties. Subscribe However, with that same unit, veteran Ben Bartch (foot) is likely to miss Sunday’s matchup with the Jets. The left guard competition that’s been ongoing since May has effectively been whichever option is healthy that week. In the back end, safety Thomas Harper (ankle) is also unlikely to be available on Sunday. That leaves the team precariously thin at the position following Avonte Maddox going on injured reserve this week. Christian Izien is expected to get the start alongside Chuck Clark. “Izzy's been working a lot back there and had a full week,” Campbell said. “And he's gotten a ton of work this week, a ton of reps, full-speed reps. ‘This is what you're going to do, this is the calls’ and just dousing him with full-speed reps and he's done a good job this week.” Safety depth is the bigger concern. The team is expected to count on some combination of Jalen Mills, who signed to the practice squad on Monday, Bishop Fitzgerald, the undrafted rookie poached off the Steelers’ practice squad on Tuesday, and rookie cornerback Keith Abney, who doesn’t have experience at safety. “I'll say this about Abney, man, for a rookie, he's a pretty dang smart, conscientious, aware football player that's got a ton of room to really take off,” Campbell said. “…He's young. He's another one, he just needs reps and reps. But, if we need it, that'll be a guy who may have to go in for us.” You can check here for the full injury report, with game designations, later this afternoon. Reflecting on the past Responding to comments made by Jets coach Aaron Glenn this week, Campbell reflected on his earliest days with the Lions, before the coaching staff had been fleshed out and it was just he and Glenn at the facility working through what they wanted things to look like. “It was just he and I in the lab,” Campbell said. The coach said the two would fill the whiteboard that remains in current coordinator Kelvin Sheppard’s office top to bottom with notes about philosophy, coaching style, team identity and the type of players they wanted to target. “He looks different than me,” Campbell said. “I'm taller, I'm whatever. He's quicker. All these different things, man, but we're really the same. I mean we're so much the same. And he's the defensive version, I'm the offensive version. He was my right hand man. …It was fun, man. Those were good days.” Campbell said it was one of the best and worst days of his life when the Jets hired Glenn to be their coach. “AG means the world to me,” Campbell said. “He's one of my dearest friends because I know what he's made of. “…It's because you know you're losing a little piece of you. That's what he meant to me and to us. So, that's hard.” Traits under center A couple of weeks back, Sheppard noted that Brunell had identified Saints quarterback Tyler Shough as the best prospect at the position ahead of the 2025 draft. On Friday, Brunell confirmed his evaluation and explained what he looks for when studying a young quarterback. Here’s the full answer: “Young quarterbacks, you have to look at everything, you know? I look at guys coming out of college just like I look at any free agents that we might be looking at, or guys that we might add to our roster. Do they take care of the ball? Are they on time? How is their decision-making? How are their feet? “It's tough because you look at a college player, you don't understand what they're trying to do offensively, what their reads are, but you can identify when a guy is accurate, obviously, and when the ball's getting there on time. If there are a lot of interceptions, it raises a red flag. And I think with a lot of the spread offenses of what you're seeing, when you see a young player and they're running some pro concepts and he's having to make protection calls, and he's getting the right play out of the run game, and when there's a lot on his plate and he's executing it very well, and he's managing all of that, that really jumps out at you. It’s really hard to find. “That's one thing we saw with Luke Altmeyer. He had a lot of experience. We call it, ‘Hey, he's playing quarterback.’ And what does that mean? It's not just completing passes. It's getting guys lined up, getting the right play, getting the protection call right, just fixing some problems, being able to progress (through reads). And there's still some young guys out there that can do that at a high level, which is good to see.” Regarding Altmyer, who competed for the team’s backup job through the offseason and currently resides on the practice squad, Brunell acknowledged physical development slows once the season starts, because there aren’t reps to go around. However, there’s still extensive mental development that’s ongoing. “The key for him is approach the game as if you're the starter, mentally,” Brunell said. “And that's really all you can do. Approach the game as if you're the starter and be good in the (class)room. You come in alongside Jared (Goff), and you come in alongside Josh (Dobbs) and (do) whatever they need. And if you get an opportunity to talk to Luke, he'll tell you he does have a lot of responsibilities besides just getting donuts for us on Saturday. “For him, it's mentally staying focused, and even though there's really no chance this Sunday of him playing, he has to approach it as if he's taking the first snap and playing the whole game. So what's our game plan? What are our checks? What are we anticipating? And then during the game, we keep him involved as far as looking at coverages and pressures. And so, really, for him, it's just a mental game. And for now, that's all we can do.” Reason for more zone The Lions have significantly increased their usage of zone coverage on defense this season. I asked Campbell if that was a reaction to their personnel or driven by the focus to generate more turnovers, given it can be easier to produce interceptions when you can keep eyes on the quarterback while playing zone. “I think it was a little bit of both,” Campbell said. “We just felt like this would suit us a little bit better up to this point, and then be disruptive and get takeaways, which worked well Week 1. We had two (opportunities) last week against Buffalo we weren’t able to get, but they’re there.” I followed up by asking how much the combination of heavy blitzing with the back end playing zone has contributed to some of the early-season coverage woes, since adding extra players to the pass rush means leaving the coverage short-staffed. “I mean, it’s challenging, and that’s why a lot of the things we’ve done in zone, for the most part, have been to reduce that stress level back there,” Campbell said. “But that also requires the front getting there. And if you don’t get there, we already kind of talked about that, but there (has to be) a trust there.” The alternative, Campbell explained is sending four and it taking longer for the rush to get home, which can create different problems for a defense. “You can bleed yards,” Campbell said about the strategy. “It gets a little longer and it’s dink-and-dunk and run after catch. …So, we do what we think is right by what we feel like our personnel (does well). But also the game plan, who you’re going in to play, the matchups, their offense. “We’re not stuck on one way.” Detroit Football Network is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Scientists Reveal the Shocking Body Temperature That Kept T. rex Alive - Futura-Sciences
Breaking Free from the Cold-Blooded Stereotype For decades, dinosaurs have been compared to the reptiles and lizards we know today. People saw them as typical “cold-blooded” creatures—scientifically called ectotherms—whose body temperature depended almost entirely on the environment. That’s why you see lizards basking in the sun or hiding in the...
Dolly Parton Day celebrated across the US: What to know
Dolly Parton attends We Are Family Foundation honors Dolly Parton & Jean Paul Gaultier at Hammerstein Ballroom on November 05, 2019 in New York City. (John Lamparski/Getty Images)
Rob Gronkowski Explains Terry Bradshaw’s Viral Trey McBride Moment
Gronkowski says the Hall of Fame quarterback was in on the joke.
Maggie Voisin Breaks Down the Science of Skiing
Maggie Voisin has spent her career learning how to break skiing down into its smallest details; speed, trajectory, timing, rotation, terrain. Years of competition taught her how to calculate a…
5 Side Hustle Businesses That Cost Almost Nothing to Start
These side hustle service business ideas can largely be launched with your skills, contacts, internet access, and time.
Politely, Taylor Swift Could Have Skipped the Encore
Taylor Swift just released "The Life of a Showgirl: The Encore." Here, a lifelong fan dives into why the pop star could have skipped the curtain call.
Coding a Community for Women in Computer Science
For Colgate University students interested in computer science, finding a community can be just as helpful as developing technical skills. Women in Computer Science (WCS) provides students with opportunities to create meaningful connections, develop professional skills and support other women in the computer science department. For senior and WCS co-president Frankie Williams, being a computer...
Pioneer of China NewCo model sued in US over trade secret misuse, double-dealing
A legal feud unfolding in New York is putting a spotlight on the work of a business development veteran who is credited for pioneering one of biopharma’s hottest dealmaking mechanism: the China “NewCo” model. In a lawsuit originally filed in New York state court and recently moved to federal court, China’s Lepu Medical Technology has alleged that biopharma business development consultant Su Zhang, who was hired to help shop its GLP-1 weight-loss candidates to Western partners, engaged in corporate double-dealing and trade secret leaks. According to the complaint, while acting as Lepu’s primary dealmaking liaison for a group of obesity and metabolic disease drug candidates, Zhang was secretly double-dipping as the acting chief business officer for a direct competitor, BrightGene Pharmaceutical. “She never adequately disclosed the role, never sought Lepu’s consent, and never proposed any safeguard,” Lepu alleged in its complaint, which was filed in July after Zhang’s consulting firm, CoDevCo, sought certain transaction-based success fees from its angry customer through an arbitration process in Singapore. Lepu, the parent company of Lepu Biopharma, has asked Zhang to pay back its $500,000 retainer and disgorge all benefits she received during the alleged breaches of fiduciary duty, plus other damages and relief. The company has also requested the court grant injunctions to protect Lepu’s trade secrets. The ill-fated partnership officially kicked off in December 2024, when Lepu tapped CoDevCo as its “exclusive business development mechanism” to identify collaborators for the company’s drug candidates. According to Lepu’s complaint, Zhang personally negotiated and signed the agreement as managing director for CoDevCo, which used her home address. Before the Lepu deal, Zhang made a name following a short stint as the global head of business development for Hengrui Pharmaceuticals. It was during her tenure that Hengrui signed a landmark deal granting exclusive rights for a portfolio of GLP-1 assets to Hercules, which was at that time newly established by a group of private equity and venture capital firms. In addition to the regular upfront and milestone payments, Hengrui also gained an equity stake in Hercules, which later became Kailera Therapeutics. The Hengrui-Hercules deal opened a new paradigm, where a Chinese biopharma company spins off certain early-stage assets to investors for further development through the creation of a new company abroad. The “NewCo” model quickly came into vogue as it allows Western investors to access high-potential assets originating from China at an early stage while giving the Chinese licensors an opportunity to reap long-term benefits through equity stakes in the new firms. The NewCo model proved its value when Kailera staged a record-breaking $625 million IPO on Nasdaq this April, merely two years into the Hengrui deal. Related Kailera CEO 'knew we were in a good spot' before obesity biotech's record-breaking $625M IPO On her LinkedIn page, Zhang described her work at Hengrui as “[b]uilding team and capability from the ground up,” forming NewCo and major pharma partnerships worth billions of dollars. Lepu clearly wanted that kind of track record to help boost its own cardiometabolic portfolio, which includes a range of assets for obesity, Type 2 diabetes, fatty liver disease and muscle preservation during weight loss treatment. “Lepu’s pipeline is very valuable, but only if Lepu could secure the right international partner to expand into the overseas market during the available commercial window,” the company argued in its complaint. The Chinese biotech said it had little knowledge of U.S. laws, customs or business practices in the business development field, and therefore “needed to rely entirely” on the expertise of Zhang and her team as the firm’s first engagement of a U.S.-based BD consultant. “Zhang’s dominating influence on the business development strategy is further evidenced by the fact that she personally controlled the business-development communications on behalf of Lepu with potential partners,” Lepu said in its complaint. After entering the deal, Zhang introduced Lepu to her four associates. According to Lepu’s version of events, all of them were allegedly employed at different time points to perform similar jobs at other Chinese companies that Lepu described as its competitors, while having access to Lepu’s confidential information. As such, Lepu described Zhang’s team as “a roster of individuals whose primary professional loyalty, by virtue of their concurrent full-time employment, ran to Lepu’s competitors.” As well as the specific examples set out in the case, a look at Lepu’s deals over the period suggests Zhang may have been involved in at least one transaction. During their partnership, Lepu, through its subsidiary Shanghai Minwei Biotechnology, also out-licensed its GLP-1/GIP/FGF21 agonist MWN105 to a NewCo called Sidera Bio in the fall of 2025. The deal included an upfront and near-term payment of $35 million, up to $1.01 billion in milestones, and a 9.99% stake in the Danish startup. It seems likely that Zhang facilitated the Minwei deal given that Lepu is on record as having used CoDevCo as its “exclusive business development mechanism.” The big shock for Lepu came in the form of a news article on June 25, 2025. The article, reporting on phase 2 data for BrightGene’s GLP-1/GIP receptor agonist BGM0504, identified Zhang as acting chief business officer of the Lepu rival. Blindsided by her association with BrightGene, Lepu confronted Zhang in July 2025. “Lepu was given assurances that there was nothing to be concerned about and told that Zhang would explain the matter to Lepu,” Lepu alleged in its complaint. “Zhang never did.” Lepu claimed that Zhang had the motive and opportunity to steer potential prospective partners toward BrightGene or other competitors. Later, in February 2026, one of Zhang’s associates joined BrightGene as the vice president for global business development, according to the complaint. Around the same time, Lepu sent written demand letters asking Zhang to account for her BrightGene role, identify what confidential data were shared with the rival firm, and provide any conflict-of-interest or firewall policies during the engagement. According to Lepu, neither CoDevCo nor Zhang answered the questions in their responses. Related Novo vs. KBP: How a $1.3B deal turned into a fraud accusation and an international legal fight In a motion to dismiss filed with the U.S. District Court in the Eastern District of New York on Sept. 4, Zhang’s legal team argued that Lepu’s agreement was signed with CoDevCo, and that an employee of the contractor does not owe fiduciary duties to the client. In its complaint, Lepu said: “That CoDevCo was the contracting entity does not insulate Zhang from personal liability for duties she personally undertook and personally breached.” Taking the argument one step further, the defending party argued that the consulting agreement “does not create a fiduciary relationship even between CoDevCo and Lepu; instead, it identifies CoDevCo as an independent contractor retained to market Lepu’s business to potential western partners.” Although CoDevCo was Lepu’s exclusive business-development contractor, there were no terms stipulating that the consulting firm should serve only Lepu, Zhang’s lawyer noted. As to Lepu’s claims that Zhang misappropriated trade secrets, the defendant argued that Lepu authorized the use of the information so Zhang’s team could perform their service per the agreement. In a rebuttal filed on Sept. 11, Lepu’s lawyer set out why they believe the Chinese biotech satisfied New York law’s misappropriation definition by alleging that the defendant used a trade secret “in breach of a duty or through improper means.” As an alternative to dismissing the suit, the defendant suggested the action should be stayed pending outcomes from the arbitration of a separate case in Singapore. While NewCo pioneer Zhang is defending her business arrangements, momentum behind the NewCo trend has continued unabated into 2026. Through August, Chinese biotech assets have spurred 15 NewCo deals this year, according to local trade publication PharmaDJ.
Polanski heckled at Jewish community hustings after saying that Zionism is a form of racism
The Green leader, who is Jewish, made the remarks as part of his campaign in the Holborn and St Pancras byelection
There’s a central place to donate to help Walhalla businesses destroyed in massive downtown fire
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Is metascience being co-opted?
In July, the White House released a report that argued academia is deeply dysfunctional and in need of radical reform.Science: A New Golden Age sets out a litany of problems many academics will recognise: interminable waits for grants; short-term funding rather than support for longer, more ambitious projects; ballooning administrative requirements; pressure to publish, and many more. “The scientific machine is getting bogged down,” it says. At least on the face of it, Science: A New Golden Age is a triumph for the metascience movement, a loose-knit, global group of academics, philanthropists and think tankers that want far more testing and experimentation in how we fund public research and innovation. The report tells US research funders to set up internal metascience units to do just this. But it has also set alarm bells ringing that metascience is being conveniently deployed to help justify the defunding of US universities, which US vice president JD Vance has openly labelled “the enemy.” “Just because you have an issue with your plumbing in your house doesn't mean you light the entire house on fire and burn it to the ground,” said Colette Delawalla, chief executive of Stand Up for Science, a group campaigning against what it says are attacks on scientists by the Trump administration. No one is arguing that academia doesn’t need reform, but there’s debate over how far and how fast the system should be shaken up. Does public R&D need slow and steady evidence-based adjustment, or radical new experiments?One of the key arguments in Science: A New Golden Age is that there’s not enough funding for what it calls “mid-level” science: engineering-heavy projects that require tens of millions of dollars, involve ten to a hundred people, and last around five years. Such a project might develop a brain-computer interface for people with Alzheimer's disease, for example. As such, the US National Science Foundation (NSF) has already announced $1.5 billion to set up so-called X-Labs, effectively new research organisations to pursue breakthroughs in areas such as quantum sensing and new scientific instruments. Funding divertedBut there’s a catch: this money has squeezed NSF budgets for more traditional, fundamental research grants, Science reported in June, likely meaning less cash for university-based scientists. Science: A New Golden Age also makes various swipes at universities, accusing them of extracting overheads from scientists to fund administrative bloat. “We have become dependent on a narrow set of legacy institutions,” it says. The report doesn’t mention it, but the US government is simultaneously seeking greater powers over federal funding, which would allow political appointees at funding agencies to screen or cancel research grants mid-project. The White House is also seeking to slash the NSF’s budget by more than half in 2027, although similar cuts proposed for 2026 were blocked by Congress. Convenient hookThis has worried some that the metascience agenda could be misused as a kind of smokescreen to further weaken universities. James Wilsdon, executive director of the Research on Research Institute at University College London, said that the report contains lots of “interesting ideas” and agrees that in places, academia is a “pretty broken system.” But the risk is that metascience is being deployed as a “convenient hook” to support cuts and a “political land grab” to transfer grant power from scientists to political appointees in US funding agencies.So far, the metascience agenda hasn’t been seized on by radical right parties in Europe. But Wilsdon worries it will cross the Atlantic, politicising research reform efforts and making them more difficult to carry out. The report is already making some in Europe sceptical of the entire idea. “The system is not without flaws, but the metascience discussion is not likely to improve the system but rather to generate munition to undermine it,” said Claes de Vreese, a professor of AI and society at the University of Amsterdam. Peter Thiel protégéOfficially, Science: A New Golden Age has just one named author: Michael Kratsios, the director of the Office of Science and Technology Policy and a former chief of staff to Silicon Valley mogul Peter Thiel. He also served as chief financial officer of Thiel’s Clarium Capital Management. Since the 1990s, Thiel has criticised US universities for moving away from teaching what he views as the classic works of western civilisation, and drifting towards “anti-Western zealotry.” And since 2011, he has offered two-year fellowships of $250,000 to young people to skip or drop out of university, and instead start companies or pursue scientific research. “College can be good for learning about what’s been done before, but it can also discourage you from doing something new,” according to the Thiel Fellowships website. In other areas, the Trump administration has promoted academics with a longstanding interest in metascience. For example, the head of the National Institutes of Health, Jay Bhattacharya, in 2020 co-authored a study arguing the funder backs overly conservative proposals, although he achieved wider prominence as a critic of pandemic lockdowns. Careless talk costs fundingEven before the Trump administration embraced the metascience agenda, some metascientists privately wondered whether they should be careful not to overstate dysfunctions in academia, in case this gets used as ammunition against universities. But others think being cautious with criticism is pointless. After all, last year, the Trump administration sought to cut funding from US universities on an entirely different premise: supposed antisemitism on campus. “I don't think these governments need a technical metascientific excuse to attack the universities, they will want to do so anyway,” said Will Stone, a researcher at Science Works, a new think tank advocating for a “metascience revolution” in the UK. “I think researchers should report what they find, even when the findings may be used to advance policies they disagree with,” echoed Russell Funk, a researcher at the University of Minnesota, who in 2023 co-authored a highly influential paper that argued scientific papers were becoming less disruptive over time. No justificationThat said, Funk thinks that metascientific research certainly doesn’t justify a weakening of universities. Instead, scientists need “time, resources and stability to pursue unfamiliar ideas,” he said. “Taking away those conditions works against the very goal the reforms are supposed to achieve.”The Institute for Progress, a Washington DC-based innovation policy think tank that has championed X-Labs and metascience units, also says that reforms should complement, not supplant, universities. “Unpredictable, unreliable, and reduced federal funding to researchers is destabilising to the very foundations of research and development and is bad,” said Jenn Gustetic, the institute’s director of metascience and R&D policy.Evolution or revolution?This points to a much bigger divide in the metascience community: how far and how fast should public R&D be shaken up? Does it need evolution or revolution? For example, Science: A New Golden Age says the science system relies too heavily on traditional “workhorse” project grants, the type that pay out around $250,000 a year to fund “hypothesis-driven science by small teams on tractable questions.” However, in criticising project grants, the report “decisively picks one side of a debate that is far from settled,” David Hilmer Rex, a metascientist based in Denmark, has written. In June, Pierre Azoulay, a metascientist at the Massachusetts Institute of Technology, defended project grants, saying that the alternative of X-Labs “merits scepticism.”A-B testingOne challenge in metascience is that it’s easier to generate evidence for some types of change than others. Most straightforwardly, research funders can run A-B tests on different ways of awarding money. For example, Germany’s Volkswagen Foundation recently trialled distributed peer review, where applicants rate each other’s proposals, and measured its results against traditional review panels. Distributed peer review made quicker decisions, although awarded money to largely different ideas. However, much of the focus of the metascience movement has been on founding fast-moving and free-acting new research organisations and funders, in contrast to the alleged stodginess of mainstream academia or public innovation grants. A culture of speed and freedom are the animating principles behind Germany’s Sprind or the UK’s Advanced Research and Invention Agency (Aria).Related articlesViewpoint: it's time to experiment with how Europe funds science European researchers sound the alarm that Trump rule changes will hit cooperationHowever, while it’s possible to closely study previously successful bodies, such as the US Defense Advanced Research Projects Agency (Darpa), for historical clues to their secret sauce, it’s impossible to guarantee in advance that the likes of Sprind or Aria will actually work as hoped. But advocates of new organisations say this inherent uncertainly shouldn’t stop us trying. “If we wait for definitive proof that something will work before we try it, I don't know where your proof is coming from,” said Stone. Trade-offsUp until now, experiments in metascience haven’t generally come with hard trade-offs over money. In the US, new ideas such as focused research organisations have often been funded by billionaire philanthropists. In Europe, new innovation agencies such as Sprind and Aria, or the Netherland’s new National Agency for Disruptive Innovation, haven’t needed explicit cuts elsewhere in the research system. But with the $1.5 billion establishment of X-Labs by the NSF, the trade-offs are becoming clearer. Some metascientists privately wonder whether a smaller pilot would have been more appropriate, given that the idea is untested. The Institute for Progress counters that the $1.5 billion X-Labs budget is spread out over a decade, so will account for less than 2% of the NSF’s annual budget. “It’s important to remember that [Darpa] was once an institutional experiment as well. Now it’s one of the most cited innovative funding models in the world,” said Gustetic.As for Europe?The US isn’t the only country placing metascience at the heart of its research strategy. Science: A New Golden Age looks admiringly at the UK, which in 2024 set up a Metascience Unit to scrutinise how it funds research. In Brussels, it’s more of a mixed picture. In 2018, the EU set up the European Innovation Council to funnel grants and equity to start-ups, although it’s sometimes criticised for awarding money too slowly. Recently, the council has started experimenting with challenges, where teams of inventors compete to overcome a technological challenge. The European Commission also wants to experiment with partially randomising grant winners, to cut down on bureaucracy. However, the Commission’s own advisers have said the EU’s own research schemes are too conventional. They want the Commission to establish a new dedicated unit to scrutinise and experiment with funding. But there’s no sign of a such unit emerging in Brussels’ plans for the next Horizon Europe programme, which from 2028 is set to distribute more than €160 billion over seven years. Sam Bogerd, director of breakthrough innovation at the Brussels-based Arq Foundation, an AI-focused think tank that also looks at metascience, says that Europe might have the opposite problem to the US: universities and basic research funding are still reasonably well supported, but there’s not enough experimentation. “We're not taking a close enough look at where this money can achieve the most, and I am worried that the good ideas around metascience will be tainted politically by their association with the Trump administration,” he said. He’s still lobbying for the Commission to set up an experimental unit. But in the meantime, the Arq Foundation plans to do its own research, and is currently hiring two metascience researchers to run the rule over how Brussels spends research funding.
EU science policy wonks debate prospect of stronger ties with Canada
Europe’s research and innovation sector has started asking questions on how European Commission President Ursula von der Leyen’s offer to make Canada “the first associate member of the EU” would actually work in practice, and who will get to shape priorities in a transatlantic relationship that is getting stronger. The Commission says it wants “a new model of association” under which the EU and Canada will aim to develop “a shared space” to face ongoing challenges. “Working in close coordination with our member states and the European Parliament, we will aim to create a new form of partnership that has not existed until now, building the closest imaginable form of association with a partner outside Europe,” a spokesperson told Science|Business.Locked in an escalating trade war with US President Donald Trump, who has repeatedly talked of annexing Canada, Prime Minister Mark Carney has been looking east, but full EU membership was never in play. Taking the floor a day after von der Leyen’s proposal, he agreed to strengthen ties under “an alliance of the future” but reined in enthusiasm on the new label. He also suggested expanding Canada’s involvement in the Erasmus+ student mobility scheme, to which it currently has limited access, and the next iteration of Horizon Europe. Canada joined the present Horizon Europe in 2024, but only contributes to collaborative projects.Neither side has detailed the next practical steps in developing this new relationship. “I think nobody at the moment truly knows how this will work,” said Michael Browne, chief executive and founder of Crowdhelix, a global collaborative network that connects players in research and innovation. “It’s more of a statement of intent for closer collaboration, which requires legislative frameworks and approval processes, which have not started.”Kurt Deketelaere, secretary general of the League of European Research Universities, said von der Leyen’s pitch to Canada is “politically significant, but the legal content still has to be negotiated and constructed.”Mattias Björnmalm, secretary general of the Cesaer university group, agreed that she had only opened “a political door” to Canada, as “associate membership does not come with a predefined set of rights in the EU institutions.”Not only does this status not currently exist as a legal category in the two treaties that set up how the EU functions, but the Commission president cannot unilaterally create a new category of EU membership.According to Deketelaere, Article 217 of the Treaty on the Functioning of the EU, which allows the bloc to make association deals with non-EU countries involving reciprocal rights and duties, is “the most obvious existing legal basis for building a much deeper EU-Canada relationship.”Getting universities involvedNo matter how this new cooperation takes shape, Liviu Matei, who heads the School of Education, Communication and Society at King’s College London, hopes to see universities involved in discussions from an early stage.“Its primary motivations, entirely justifiably, are political and geopolitical,” he said. “In the area of higher education, however, restricting the initiative to political and geopolitical considerations would limit the scope of cooperation and lead to distorted frameworks and counterproductive implementation.”It is all the more important since academic interests on the two sides of the Atlantic are “neither identical nor fully aligned,” Matei added. “This is not insurmountable; it simply requires work to articulate the details of this privileged cooperation, including its governance and funding frameworks, as well as its substantive content in education and research.”Related articlesCanada looks to deepen research and education links with the EUZaharieva hopes for a Horizon Europe deal in 2026Canada might participate in European Research Council schemes, for example, which was not on offer in the present Horizon Europe association agreement. But “there would have to be something in it for the EU,” Browne said. “They don’t want to be funding projects outside of the EU where intellectual property is going to sit outside of the EU. There has to be some kind of transfer of knowledge.”But access to funding will not by itself resolve all the practical difficulties of working together, said Björnmalm. “For researchers and students, these include visas and residence arrangements, recognition of qualifications and study periods, and the conditions for pursuing a research career across borders,” he said. “For universities, there is scope for more predictable access to shared laboratories, computing and research data, and stronger support for joint doctoral training and long-term institutional partnerships.”Linda Doyle, provost and president of Trinity College Dublin, said Europe should strive for the “closest possible expression” of this new political alliance. “If Europe is serious about recovering its voice and its place in the world, it needs to be strongly allied with countries who share its values and its vision for a stable, rules-based, peaceful world.”
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