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‘Malcolm in the Middle: Life’s Still Unfair’ review: A lifeless revival
Save for Bryan Cranston, the "Malcolm in the Middle" revival is less an engaging revival than it is a tiresome dragging out of a television corpse.
We have no idea if Iran can still build a bomb
The central goal of the war is nowhere near a resolution.
Republicans block Democratic bill to end Iran war amid tenuous ceasefire
Republicans in the House of Representatives blocked Democrats from considering a measure to halt military hostilities in Iran.
Apple Apparently Still Undecided on iPhone 18 Pro Dynamic Island
Apple is weighing two options for the iPhone 18 Pro's Dynamic Island, and a final decision has yet to be made, according to the Weibo leaker known as Digital Chat Station.
3L Rachel Sadler Charts Path in Brain Health, Technology, and Policy Through UC Law SF’s Health Law Concentration - UC Law San Francisco (Formerly UC Hastings)
3L Rachel Sadler studies health law and policy at UC Law SF while researching the legal implications of neurotechnology and other emerging tools that may affect human cognition. 3L student Rachel Sadler shares how UC Law SF’s Health Law Concentration prepared her for a career focused on the intersection of brain health, government policy, and technology. Gained a detailed understanding of how U.S. health care is regulated and where policy reform is needed through coursework and research. Interned with state and federal agencies that regulate health care services and worked with a major health care provider’s bioethics department. Plans to pursue a career focused on protecting cognitive liberty and mental privacy as new technologies reshape healthcare. 3L Rachel Sadler: The Health Law Concentration has given me fluency in one of the most complex regulated industries and the tools to become an effective advocate for better health policy. Before coming to law school, I spent a decade teaching and working with teachers and administrators on high school programming for multilingual learners. Healthcare kept emerging as the most powerful driver of student outcomes. I wanted to understand how to make effective policy change in this area and how to use existing law to defend people’s health rights in California. Through the concentration’s coursework, I gained a sophisticated understanding of how U.S. healthcare is regulated. I also learned where the pressure points for reform exist. The courses gave me space to develop what became my central research interest: how law and policy can be built to protect human cognition and healthy brain development, particularly regarding new technologies such as generative AI and neurotechnology. The health law faculty were instrumental in that process, genuinely invested in helping me and other students define and pursue our own intellectual vision. During law school, I interned at the General Counsel’s Office for Region IX of the U.S. Department of Health and Human Services. I also externed at the California Department of Justice’s Health, Education and Welfare Division. Additionally, I externed at Kaiser Permanente Northern California’s Bioethics Department. Alongside those placements, I conducted extensive independent research on mental privacy and emerging neurotechnology, working closely with Professors Emily Murphy and George Horvath. That research became the throughline of my law school experience and the foundation of my current policy focus. I must also credit Nicole Ozer of the Center for Constitutional Democracy (CCD), whose deep knowledge of California privacy law and the public-interest privacy landscape deeply informed my work. I currently serve a research assistant with the CCD, where I spearhead the development of K-12 educational resources in partnership with law faculty and students. I’ve found UC Law SF to be an ideal place for second-career, nontraditional students. There is a tremendous diversity of life and career experience here, and I felt fully welcomed into the community, despite returning as a student at a different stage of life. I came to law school wanting to promote equity in California’s healthcare system. I am leaving with a sharper and more specific ambition: to build a policy career focused on protecting cognitive liberty and mental privacy from technological intrusion. This is both an urgent and underserved area of law, and I want to be part of defining this landscape going forward. Whether as a practicing attorney or a policy advisor, I plan to work on these issues after law school. I strongly recommend UC Law SF and the Health Law Concentration. When I arrived in law school, I worried the concentration would be narrow and that my non-clinical background would be a disadvantage. The opposite was true. The health law faculty thinks about health expansively, encompassing social determinants of health, structural inequity, and emerging technologies alongside the regulatory mechanics of the industry. The faculty are accessible, intellectually generous, and genuinely invested in students’ development. I found my research vision here, and I deeply appreciate the concentration’s role in this. The Evidence of Success series highlights UC Law SF students as they share how the College’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.
Warriors still waiting for a real glimpse at their highest on-court priority
After hoping to evaluate the Steph Curry-Kristaps Porziņģis synergy for at least four games, the Golden State Warriors now will have no more than two.
As Trump throws lifeline to coal plants, critics warn of higher costs and health risks
WASHINGTON (AP) — Before Donald Trump returned to the White House, the Biden administration and many electric utilities were building a future dominated by renewable energy. They aimed to replace coal, slashing greenhouse gases and reducing air pollution that kills more than a thousand people ann...
How to make a high-deductible health plan and HSA work for you
If you chose a cheaper health plan, you may be stuck with some hefty medical bills until you meet your deductible. Here's how to get the most out of your plan and health savings account.
China's car sales extend declines in March
China's car sales fell for a sixth straight month in March, as rising fuel prices hit demand for gasoline models while electric vehicle sales still reeled from reduced incentives as the economic recovery is sputtering.
Italy’s Meloni Vows to Govern Until End of Five-Year Mandate
Italian Prime Minister Giorgia Meloni vowed to stay on until the end of her government’s mandate, seeking to stabilize her tenure after a bruising referendum loss last month.
What the 'Science of Reading' Movement Has Meant for English Learners (Opinion)
We should think of reading instruction for multilingual learners as a bridge, not a checklist.
Strait of Hormuz traffic still stalled despite US-Iran ceasefire
Movements are dominated by smaller, risk-tolerant operators, while mainstream oil majors and large global shipping firms remain absent.
US fertility rate dropped to another record low in 2025
The fertility rate in the United States has been trending down for decades, and new federal data shows that another drop last year brought the rate down to the lowest on record.
Kansas City youth sports complex proposal prioritizes local students
The City Council will vote Thursday on a resolution directing the city manager to identify property and financing for the facility.
The war is on hold. But the economy is still in danger.
The best-case scenario for the Iran crisis is still pretty bad.
Iran war spurs renewed Democratic calls for war powers resolution
Democratic Party leaders are renewing calls to curb President Donald Trump’s war powers, including one Democrat who previously voted against ending U.S. involvement in Iran.
Opinion | NASA Flew by the Moon, but Behind the Scenes, Its Science Is a Chaotic Mess
Without science, the stunning images of Earth from space are only pretty pictures.
U.S. Forces Stand Ready to Resume Combat. The President May Not Be as Enthused.
President Trump knows that even if a cease-fire runs out with no final agreement on the issues dividing Washington and Tehran, the political risk of renewing hostilities is high.
Oil is crashing, but don’t expect $3 gas anytime soon. Here’s why
Oil futures are plunging – but it could still take weeks or months before gas prices are dramatically lower.
NYT report details divisions inside Trump’s inner circle as the president weighed striking Iran
Wisconsin Governor Faces Thursday Deadline on Online Sports Betting Bill
Gov. Tony Evers has until Thursday to mull a bill that would expand Wisconsin’s retail-only sports betting to also allow online wagers on tribal land.
'Euphoria' made her a star. Now she's diving into the internet's darkest corners.
Barbie Ferreira opens up about her dark new role in "Faces of Death," navigating fame in the internet age and why she's still watching "Euphoria."
Darren Till signs with BKFC after Misfits split: 'I’m coming to be the face of violence'
The former UFC star and Misfits Boxing veteran announced a multi-fight deal Tuesday that will see Till debut on May 30 at BKFC 90 in Birmingham, England.
'Malcolm in the Middle' returns after 20 years with questions of legacy and its trademark craziness
Hulu has revived “Malcolm in the Middle” with a four-part series subtitled “Life’s Still Unfair.” | KNSS Radio
'Malcolm in the Middle' returns after 20 years with questions of legacy and its trademark craziness
Hulu has revived “Malcolm in the Middle” with a four-part series subtitled “Life’s Still Unfair.” | 1010 WINS
'Malcolm in the Middle' returns after 20 years with questions of legacy and its trademark craziness
Hulu has revived “Malcolm in the Middle” with a four-part series subtitled “Life’s Still Unfair.” | KMBZ
With Orion still flying, NASA is nearing key decisions about Artemis III
One of the questions is what the initial orbit will be for Artemis III."
James Bond game 007: First Light delayed a bit on Nintendo Switch 2
IO Interactive's 007: First Light is still targeting a May release, but its Nintendo Switch 2 port won't arrive until later.
Pentagon says US forces ready to resume combat operations if ordered
WhatsApp starts rolling out usernames in beta, keeps your phone number private
WhatsApp has started rolling out support for usernames, allowing users to keep their phone numbers private while still using the app.
From classroom to the pros: Rice sport analytics program turning data into opportunity
Rice’s sport analytics program, a relatively new and still rare undergraduate major, is quickly becoming a pipeline into professional sports.
A new generation of politicians of colour is emerging in France. The backlash speaks volumes
Local elections have led to a surge of racism in a country that still struggles to see itself as anything other than white, says Guardian Europe columnist Rokhaya Diallo
Why the U.S. Navy’s retail business is fighting Walmart and Amazon to fund its own future
The Navy runs more than 300 stores globablly but its operations are at risk because retail giants like Walmart, Amazon and Target are taking market share.
'I'm Still Beyond Confused Why They Didn't Go the Cyberpunk Route' — Crimson Desert Female Character Creator Mod Lets Players Unshackle Themselves From Premade Kliff
One of the major criticisms of Crimson Desert I’ve seen since launch is that it does not let you create your own character. Instead, you’re locked into playing as Kliff, who himself has been criticized for a lack of personality, and two other even less fleshed out playable characters. Well, now, like so many other things with Pearl Abyss’ open world action adventure, there’s a mod for that.
NASA chose an old DSLR as its primary Artemis II camera
It still beats the best mirrorless cameras where it matters most
🤔 Last season plagued by injuries: VfB star's future still unclear
His contract with VfB Stuttgart only runs until the summer. For many, it was surprising anyway that midfielder Nikolas Nartey had been given another contract by the Swabians last year. Above all, num...
Do adaptogens really work? What the science says
Adaptogens are popular plant and fungi compounds, but the science on their effectiveness and safety is still evolving.
Democrats lost in Marjorie Taylor Greene’s old district. They still had one of their best election nights in recent memory
At this point, it’s not really news that Democrats are doing very well in special elections and other races held since the 2024 presidential contest. Their recent track record is abundantly clear. But even by their recent standards, Tuesday was a very good night – one of their best of the Trump era, in fact.
Viewpoint: FP10 should remain open, excellent and secure
Europe is right to worry about research security. Foreign interference is real. So is the misuse of sensitive knowledge. Universities working in sensitive areas such as AI, quantum, semiconductors and advanced materials cannot afford to ignore the geopolitical environment around them.But Europe is in danger of drawing the wrong conclusion, one that would increase, not reduce, its strategic vulnerabilities.If the EU applies an “EU preference” logic to the next Framework Programme for research and innovation (FP10), it will weaken one of its greatest strategic assets: a research system built on openness, excellence and international collaboration. In the name of security, Europe could end up advancing science more slowly, innovating less effectively and making itself less attractive to global talent and partners in advanced science and technology.That would be a serious mistake.The EU preference included in Article 10 of the proposed European Competitiveness Fund may make sense in some industrial or deployment contexts, but is far harder to justify when applied to collaborative research in advanced science and technology, where excellence and global connectivity are crucial. Research is not procurement. It does not thrive when isolated. It advances through access to the best ideas, the best people, the best facilities and the best data, wherever they are found. This is why FP10 should not simply absorb industrial policy logic by default. Doing so would risk importing instruments that are ill-suited to research and that ultimately increase vulnerability rather than resilience.For universities of science and technology, the issue is especially acute. These institutions sit at the frontier of knowledge and technology creation in the very fields Europe sees as critical for its future competitiveness and resilience. They know better than most that security risks are real. But they also know that openness and security are not opposites. In practice, they have to be made to work together. Research security is not about closing doors. It is about building resilience through collective responsibility, trust, proportionate safeguards and better governance. That is a fundamentally different approach from default restriction.The risks of non-collaborationThe real danger in the current debate is that Europe talks too much about the risks of collaboration and not enough about the risks of non-collaboration. Those risks are strategic too. Cut researchers off from international networks and Europe loses access to knowledge, data, infrastructures and talent. Slow down global collaboration in critical technologies and Europe slows down its own progress on cutting-edge science. Make participation rules unpredictable and Europe weakens its attractiveness to researchers and investors alike.In other words, over-restricting collaboration will create strategic vulnerabilities, particularly in advanced science and technologies.This point is often underestimated in policy discussions that frame openness mainly as a value to be defended. Europe’s scientific strength, technological development and long-term competitiveness depend on remaining connected to the best research ecosystems in the world. For a continent that wants to accelerate deep tech, strengthen industrial capacity and reduce strategic dependencies, weakening the excellence base would be self-defeating. That does not mean ignoring risk. Quite the opposite. Universities are already strengthening due diligence, internal governance, awareness-raising, screening procedures and compliance support. Across Europe, institutions are working to manage risks linked to foreign interference, sanctions, export controls and the misuse of research. The right response is not complacency. It is better risk management. But that means targeted, evidence-based and proportionate measures, not blunt top-down restrictions with wide spillover effects. In the daily reality of universities, openness and restriction often coexist. The real challenge is how to apply safeguards without sliding into securitisation that damages academic freedom, open science and international cooperation. Restrict partners, not nationsMore restrictive treatment of collaborators from European Economic Area members Iceland, Liechtenstein and Norway, or from Switzerland and the UK, is strategically very difficult to justify. These are deeply embedded partners in Europe’s research and innovation ecosystem. Beyond that, Europe should still resist default exclusion and instead rely on case-by-case assessment. The relevant question is not nationality in the abstract. It is the actual risk profile of a collaboration: the institution, the affiliations, the field, the knowledge involved, the intended use and the safeguards available. Screening should focus on institutions and affiliations rather than nationality alone. Related articlesParliament ‘misreads’ link between Horizon Europe and ECF, Commission official saysFrustration grows at governance gap in next Horizon EuropeIf EU preference logic is imported into research without careful calibration, the likely result is a chilling effect. Researchers may step back from legitimate and beneficial collaboration, even where risks are manageable. International partners may see Europe as less predictable. And Europe may end up undermining the very excellence base it needs to compete, scale up and lead in strategic technologies, thereby increasing its dependence on others.FP10 should do the opposite. It should remain open by default, with restrictions used only exceptionally, and then on the basis of clear evidence. It should integrate research security into open science and research integrity frameworks, not set them against each other. And it should recognise that academic freedom, scientific excellence and responsible international collaboration are not obstacles to Europe’s security, they are part of it. Europe needs stronger tools to protect itself. But it also needs the discipline to avoid measures that would weaken it and increase its strategic vulnerabilities in the process. In FP10, that means staying open, excellent and secure.Louise Drogoul is senior advisor for innovation and sustainability at the Cesaer university association.
Together for health and standing with science for our planet and its people
Himalayan spikenard (Nardostachys jatamansi) © Morten Ross / iNaturalist Statement by CITES Secretary-General Ivonne Higuero on the occasion of World Health Day 2026CITES is a multilateral
The ‘oldest fossil octopus’ is probably another animal
In 2000, researchers thought they found the oldest fossil octopus, which lived over 300 million years ago. But it may just be a half-rotten nautilus.
Cook Political Report's New York U.S. House race ratings unchanged from January
Cook still only labels one race a true "tossup" — Republican Rep. Mike Lawler in the 17th Congressional District.
Vanguard Settles on ESG — BlackRock and State Street Fight On
Vanguard’s settlement in Texas v. BlackRock marks a historic victory for the anti-ESG movement. But BlackRock and State Street are still fighting for what remains of sustainability stewardship in the US.
Cattle futures lower ahead of direct business
At the Chicago Mercantile Exchange, live and feeder cattle were lower waiting on the week’s direct business to develop. June live cattle closed $1.22 lower at $245.80 and August live cattle closed $.50 lower at $242.37. May feeder cattle closed $3.72 lower at $366.62 and August feeder cattle closed $3.77 lower at $366.05. Direct cash […]
Democratic opposition could stymy Trump's 2027 budget blueprint
Several Democrats said the proposed budget's cuts added to their concerns about cuts to non-defense programs that were passed into law in last year’s sweeping tax and spending law, known as the Big Beautiful Bill Act.
Leonard Leo Is Still Trying to Crush His (Imaginary) Enemies with Disgusting Amounts of Money
The conservative legal activist thinks “radically woke culture” is the problem with America right now—not the climate-destroying oil and gas industry he lavishly supports.
View: AI is testing the oldest debate in business: Who’s the customer?
The oldest question in business — who is your customer — turns out to be the one OpenAI still can’t answer.
📸 Bayern's season takes an unusual turn against Real Madrid
Bayern Munich have been Europe's most prolific team this season... until now.The Bundesliga champions-elect usually make short work of opponents but it initianlly wasn't the story in their Champions L...
Venture Global cashing in as gas markets tighten
Venture Global is poised to reap significant profits from the latest global energy shock, as disruptions in the Middle East tighten liquefied natural gas supplies, The Wall Street Journal writes. The exporter, which has several Louisiana-based projects, has built a lucrative strategy around selling a sizable portion of its cargo on the volatile spot market, […]
SGMC Health Enhances Hip Replacement Surgery with IntelliJoint® HIP Technology
SGMC Health is advancing orthopedic surgical care in South Georgia with the utilization of IntelliJoint® HIP, an advanced technology used during hip replacement surgery by orthopedic surgeon Anthony D’Abarno, DO. Hip […]
Is sports betting legal in Alabama? Here's what to know
Sports betting is booming nationwide, but is it still off limits in Alabama? Here's what we know about sports betting laws in AL.
Why Do Deliberative Discussions Reduce Affective Polarization? Evidence from a Deliberation Experiment in Honduras - April 7, 2026
Deliberative democracy advocates argue that deliberation can strengthen democracy in part by reducing partisan hostility and affective polarization. Yet - Why Do Deliberative Discussions Reduce Affective Polarization? Evidence from a Deliberation Experiment in Honduras April 7, 2026
Known unknowns
We asked some of Harvard’s leading thinkers to tell us what they still don’t know, and what the answers could mean for humanity.
The Boundless Deep: Young Tennyson, Science, and the Crisis of Belief by Richard Holmes
Pantheon Review by Walter Cummins The image of Alfred Tennyson I’ve carried for decades goes back to the childhood card game of Authors that depicts him with a stately continence sharpened by a jutting black beard. He’s formidable, his aura superior. Holmes opens his biography of the youthful Tennyson by describing the similar formality of the imposing Tennyson statue at Trinty College Cambridge, sharing the honor with other Trinity greats, including Isaac Newton, Francis Bacon, and Thomas Babington Macaulay. Holmes doesn’t want to chip away at that statue but rather reveal its inner youthful core of the man—tall, handsome, and talented but unformed, emerging from a disturbed family of addicted or insane male siblings and four unusual sisters struggling under a violent alcoholic clergyman father. Alfred was certainly statuesque, but would he end up a block of unformed stone like his equally promising brothers? He was youngest of three equally regarded Tennyson brothers at Cambridge, all bright, handsome, and talented, in fact Alfred regarded by some as less promising than his elders who also wrote poetry. Yet Alfred wrote one of his major poems, “The Kraken,” at twenty, revealing both his talent, his interest in geological forces, and the haunting creature that embodied his anxieties. While Holmes focuses on Tennyson of the 1830s and 1840s, he can’t tell his story without exploring his involvement with the Victorian intellectual upheaval. Tennyson was fascinated by new scientific perspectives, following the latest findings as soon as books and articles were published. He was especially taken with Charles Lyell’s deep studies of geology and the discovery of fossils and a timeline of the planet’s development that did much to question fundamental religious assumptions. The impact of these discoveries is reflected in Tennyson’s poetry and led to the crisis in belief he shared with so many contemporaries. He was especially taken by the cycles of destruction and renewal that informed the struggles he confronted in In Memoriam, Maud, and Idylls of the King. Tennyson was only one of the eventual major figures at Cambridge at the same time, young men just beginning to realize their potential. Charles Darwin was at Christ College, although there is no evidence that he and Tennyson even met as students or later in life. Yet evolution became significant in Tennyson’s thinking and the issues of his poetry. One of Tennyson’s best and most important Cambridge friends was Edward FitzGerald, who became the translator of The Rubáiyát of Omar Khayyám and in their on and off relationship served as Tennyson’s harshest critic. FitzGerald was also a friend of the novelist William Makepeace Thackeray, the two of them partying in Paris as undergraduates. That connection led to a friendship between Thackeray and Tennyson. Others who came to play significant roles in Tennyson’s life were Thomas Carlyle, the Brownings, and the Pre-Raphaelites. Tennyson’s deepest friend at college was Arthur Hallam, who at twenty wrote a glowing review of Tennyson’s first poetry collection, travelled on European adventures with him, and fell in love with his sister Emily. Hallam was also regarded as one more very promising Cambridge student. His sudden death at twenty-two in Vienna from a stroke while travelling with his father devastated many friends, but perhaps Tennyson most of all. He did not write immediate poems of grief but took years to compile those collected in In Memoriam A.H.H., published in 1850, almost twenty years after Hallam’s death For all of Tennyson’s early poetic successes and successes, Holmes reveals him as an often troubled young man suffering periods of depression, fearing planetary upheaval, concerned about supporting himself, disappointed in romances, and worried that he would inherit the family’s mental illness tendencies. Yet despite his seeming withdrawals, he was always writing poetry that he kept private and would not let go, constantly revising. 1850 became a transformative year for Tennyson. He finally consented to publishing In Memoriam with a last-minute prologue that acknowledged God and perhaps convinced the religious Emily Sellwood to marry him after years of pursuit.. He opened up to Emily, revealing his struggles with fears of depression and “weird seizures.” The devastating event of that time was the stillborn death of his unnamed first son. It shook him, but Emily’s faith brought them closer and convinced him to believe in an afterlife. Two later sons survived. With the death of William Wordworth in April of 1950, Tennyson was named poet laureate at age forty-one, reluctantly accepting. It’s as if Tennyson’s life split in half in that year. He lived another forty years, now a recognized success, with the prestige of being an official poet writing patriotic verse, wealthy and revered, no longer the insecure young man seeking an outlet for his immense talent. He earned a place in the Authors deck, now dignified and in 1884 elevated to the peerage as Arthur, Lord Tennyson. Richard Holmes is the author of twenty previous books on the Romantics and Victorians, several of which received awards. The Boundless Deep was shortlisted for the 2025 Baillie Gifford Prize for Non-Fiction. He captures the complex vicissitudes of Tennyson’s youth, illustrated by frequent excerpts from the poetry, placing that life in the full context of the shattering discoveries that led to an upheaval of thought in the Victorian age.
A first for Michigan’s $2.4B SOAR business incentive program: New jobs
Companies say they’ve created 1,846 of the 14,559 jobs they originally promised in exchange for Michigan SOAR subsidies. They still have several years to meet their targets.
NFL Draft rumors: Jets rethinking No. 2 pick, Ohio State could own top five, Bain and Tyson falling?
With less than three weeks until the draft, these latest rumors are shaping the board
Men Are Obsessed With Their Sperm Health, and Brands Are Cashing In
Wellness brands are fueling a growing demand for male-fertility products, selling supplements and sperm-testing kits.
Microsoft explains why it still can’t fully kill Control Panel in Windows 11
Microsoft is phasing out the Control Panel in Windows 11 in favor of the Settings app, but the transition is careful due to old drivers.
Immunic COO highlights the importance of science-led innovation to mark World Health Day
Immunic Inc (NASDAQ:IMUX, FRA:10VA) chief operating officer Jason Tardio talked with Proactive's Stephen Gunnion about the importance of science-led innovation in tackling neurological diseases, particularly multiple sclerosis, on World Health Day 2026. Tardio highlighted that the biotech industry is fundamentally grounded in scientific research and data, noting that “everything we do is rooted in science.” He explained that Immunic is focused on developing innovative therapies designed to improve patient outcomes and address significant unmet medical needs. The discussion centred on multiple sclerosis (MS), a complex neurological disease that continues to present challenges despite decades of progress. Tardio pointed out that while advancements have been made, “the disease is not solved for,” with many patients still experiencing disability progression and requiring safer, more tolerable treatments. He emphasised the urgent need for innovation, particularly in progressive forms of MS where treatment options remain extremely limited. Immunic’s lead asset, vidofludimus calcium, is being developed as a novel approach aimed at addressing the full spectrum of the disease. Tardio also reinforced the broader mission of the healthcare and biotech sectors, stating that the ultimate goal is to help individuals “live a better quality of life” and “a healthier life longer.” Watch the full interview to learn more about Immunic’s approach to advancing MS treatment through science. For more videos like this, visit Proactive's YouTube channel, like this video, subscribe to the channel, and enable notifications so you never miss an update. #Immunic #MultipleSclerosis #BiotechInnovation #Healthcare #MSResearch #DrugDevelopment #ClinicalTrials #Neurology #WorldHealthDay #ScienceDriven #VidofludimusCalcium #PharmaNews #BiotechNews
The world’s “oldest octopus” was never an octopus
A famous “oldest octopus” fossil has been exposed as a case of mistaken identity. Advanced imaging revealed hidden teeth showing it was actually related to a nautilus, not an octopus. The confusion came from decay that altered its shape before fossilization. This discovery rewrites part of evolutionary history, pushing the true origin of octopuses much later in time.
Scientists discover reversible male birth control that stops sperm production
Scientists at Cornell University may be closing in on the long-sought “holy grail” of male contraception: a safe, reversible, nonhormonal method that completely halts sperm production. In a breakthrough mouse study, researchers used a compound called JQ1 to temporarily shut down meiosis—the critical process that produces sperm—without causing lasting harm. After treatment stopped, sperm production bounced back, fertility returned, and the animals produced healthy offspring.
Eagles could reload defensive line in 2026 NFL Draft
While they have outstanding depth at defensive tackle, Howie Roseman could look to add a true defensive end or a versatile edge rusher to enhance their explosive potential and reinforce their depth.
MAGA Is Winning Its War Against U.S. Science
Source: NBER With all the other terrible news right now, you may not have noticed that Donald Trump is in the process of killing American science. OK, that’s an exaggeration — but not that much of an exaggeration. The Trump administration’s latest budget proposal calls for a gigantic increase in military spending combined with severe cuts to social programs. But as the chart above shows, it also calls for debilitating reductions in research funding. Furthermore, Trump appointees have already been strangling science by sharply reducing the rate at which research grants are approved. Here, for example, is the number of new grants approved by the National Science Foundation: Source: Nature Large numbers of existing grants have also been frozen or terminated, especially in the study of infectious diseases. Add to this a sharp drop in visas issued to foreign students, who often play a direct role in research and who help support academic departments that do research: Put all of this together, and much U.S. scientific research is set to come to a screeching halt — not a few years from now, but over the course of the next year or two. This new assault on U.S. science is taking place at a time when the role of American science in the world has already been greatly eroded. The chart below, based on research recently reported by the National Bureau of Economic Research, measures national strength in science by the share of publications in highly ranked journals. In the 1990s the United States had more such publications than the rest of the world combined. Since then we’ve dropped into third place — well behind China and slightly below the European Union. And this was before the Trump administration’s attack on science had time to take its full effect. Source Some erosion in U.S. scientific preeminence was inevitable given China’s growing sophistication and wealth. But we’ve also fallen behind Europe, even though everyone says that Europe is lagging economically and technologically. Claims about Europe’s underperformance are, in fact, dubious if one looks hard at the data. But it’s still striking to see America lagging. What’s going on? There are presumably multiple factors behind America’s scientific lag. But even before Trump II the growing hostility of the U.S. right to science surely had some negative effect. And since the rise of MAGA G.O.P. attitudes toward science in general have become overwhelmingly hostile. This is true even for the Republican rank and file: And while I haven’t been able to find good survey data, it’s obvious that the anti-science turn has been even more pronounced — and began earlier — among the Republican political elite. Chris Mooney published The Republican War on Science in 2005, and even then was describing a longstanding trend. Why have Republicans turned so anti-science? Part of the answer is that they believe that scientists don’t support them. And they’re right! A study of who scientists give money to shows that only a small percentage gave money to Republicans even 20 years ago, and that almost none of them donate to Republicans now: Social scientists have always been strongly pro-Democratic, while there used to be a significant number of physical, “hard” scientists supporting the GOP. But these days physicists are almost as uniformly Democratic, or at least non-Republican, as sociologists. Why are there almost no Republican scientists? It’s not a mystery. GOP political orthodoxy includes positions that are at odds with the scientific consensus on multiple issues, ranging from the validity of the theory of evolution, to the reality of climate change, to the efficacy and safety of vaccines. In each case the scientific consensus is solidly grounded in evidence. But even before the rise of MAGA the U.S. right was increasingly hostile to evidence-based policymaking — especially, of course, where the evidence is unfavorable to fossil fuel interests or quack medicine, both financial mainstays of right-wing politics. So scientists don’t support Republicans, and the feeling is mutual. Today’s Republican Party doesn’t like science or scientists. It doesn’t like having its preconceived views challenged by appeals to evidence. It knows that very few scientists are on its side electorally. In general, it sees scientific research as a threat to its grasp on political power. Add in MAGA’s combination of rabid anti-intellectualism and allergy to any hint of criticism, and one has the makings of a drastic anti-science turn in policy. “Ignorance is strength” might was well be an official MAGA motto. And as I said, we aren’t talking about something that will happen over the course of multiple years: The U.S. scientific enterprise is threatened with severe damage, even collapse, over just the next year. There are many reasons to find this prospect horrifying: Think of all the beneficial advances, affecting almost every part of life, that won’t happen because U.S. science — still crucial to the world — has been eviscerated. But think, also, of America’s international standing. Can a nation that has forfeited its role as a leader, or even a contender, in global science, still be a Great Power? No. MUSICAL CODA
Bourbon demand is down and tariffs aren't helping. But distillers keep building.
Like many whiskey distillers, Heaven Hill Brands is rolling back bourbon production this year, as demand lags. Yet, as the American spirit faced a tumultuous market in 2025, the Kentucky company built a new, $200 million distillery in the heart of bourbon country, adding 155,000 barrels of capacity.
Physicists moved volatile antimatter by truck for the first time ever — paving the way for groundbreaking new research
CERN scientists transported antimatter by truck for the first time, enabling ultraprecise studies that could reveal why matter dominates the universe.
Government shutdown enters eighth week as Johnson faces GOP revolt over DHS funding deal
The partial government shutdown has now lasted eight weeks with Congress on recess until 13 April
'The ultimate honour' - have your say on Maguire's new deal
Harry Maguire says playing for Manchester United is the "ultimate honour" after signing a new contract extension until June 2027, with the option for a further year. The 33-year-old central defender's current deal was due to expire at the end of this season. Maguire has made 266 appearances for United since signing for £80m from Leicester in 2019 - then a world-record transfer fee for a defender - and has since won the Carabao Cup and FA Cup with the club, as well as having a spell as captain.
GOP War on Health Care Destroying Hospitals at Home and Abroad
More than 800 health care facilities are at risk or have already closed since Republicans severely cut funding last year. The worst is still ahead.
Salesforce, Microsoft new products, pricing in new era for software
Salesforce and Microsoft envision an AI future in which businesses still need their platforms — they just use them differently.
The Democrat vying to replace Marjorie Taylor Greene faces a tall task, but Republicans are still watching closely
A Democrat’s bid to pull off a major upset Tuesday in former Rep. Marjorie Taylor Greene’s ruby-red Georgia district will be closely watched by national Republicans trying to maintain a razor-thin House majority.
Is David Jolly riding an off-shore blue wave? His Q1 fundraising suggests momentum is building
Jolly still trails Republican Byron Donalds — by a lot — but he has upped his game since 2 surprise Special Election victories.
Dricus Du Plessis reveals his favorite fighters
Everyone has favorite fighters they like to watch, or that they relate to for whatever reason. Former UFC middleweight champion Dricus Du Plessis is no different. During a recent fan question and answer session, Du Plessis was asked which fighters he admired and why. "Stillknocks" listed mostly ...
Upcoming Tech and Sourcing Webinar on Digital Health
Join partner Ben Klaber and of counsels Ariel Seeley and Eric Pennesi on Thursday, April 9, 2026 from 12:00 to 1:00 pm ET for a discussion on innovations and trends in digital health. Topics will include artificial intelligence and connected devices, as well as data governance and regulatory developments.
Owner of Upstate arcade and game lounge blames liquor law changes for business shift
The owner of Pinky’s Revenge says South Carolina’s liquor law changes are driving up costs and forcing a business shift.
Instant observations: Sixers fall to Spurs despite Victor Wembanyama injury
Joel Embiid had 34 points and 12 rebounds and the Spurs lost Victor Wembanyama at halftime, but the Sixers still fell 115-102 to San Antonio in a critical playoff race...
Could Raiders still deal Maxx Crosby?
The rumors still persist, but are they viable?
NFL executive hints when, where A.J. Brown will be traded
The NFL offseason has featured a number of major transactions since the new league year began. Teams are focusing on the NFL Draft, but that doesn’t mean rosters are fully set. A few free-agent signings are still taking place. Teams…
Overwatch's Anran redesign is a massive improvement from Blizzard
Though it still features an 'Ozempic chic' nose
Scientists solve 30-year mystery of a hidden nutrient that protects the brain and fights cancer
Scientists have finally uncovered the missing link in how our bodies absorb queuosine, a rare micronutrient crucial for brain health, memory, stress response, and cancer defense. For decades, researchers suspected a transporter had to exist, but it remained elusive—until now. By identifying the gene SLC35F2 as the gateway into cells, this breakthrough opens new possibilities for therapies and highlights how diet and gut microbes profoundly shape human health.
World Health Day 2026: Together for health. Stand with science
On World Health Day 2026, celebrated on 7 April, WHO unites and mobilizes the world under the theme “Together for health. Stand with science.” celebrating the power of scientific collaboration to protect the health of people, animals, plants, and the planet. The year‑long campaign spotlights both scientific achievements and the multilateral cooperation needed to turn evidence into action.
Reduced medical residencies if governor approves cuts to public health budget
The 2026 Idaho Legislature is adjourned sine die, but the fate of some bills are still unclear. Among those still awaiting decision include a Health and Welfare
Cooper continues to lead Whatley in polls seven months out
Seven months until Election Day the race is trending toward the Democrat, but it's still early.
Fire officials release findings from 2025 Millcreek business complex fire
Millcreek Township fire officials have released the findings of a formal After Action Review (AAR) following a massive fire at a business complex in December. The assessment evaluated the departmen…
Utility board elections face surge of attention as electricity rates rise
Skyrocketing power demand from massive data centers and rising household electric bills are injecting a wave of attention into who is getting elected to watch over electric utilities.
Hochul: Length of expected second state budget extender still being determined
The current extension, passed on March 31, runs through Tuesday.
North Mississippi Allstars to bring ‘modern Mississippi music’ to the Englert
The North Mississippi Allstars are commemorating the 25th anniversary of their debut with their 12th studio album, "Still Shakin.’” The band will perform Sunday, April 12, at the Englert Theatre.
Tariffs still challenge Brookside business one year later
Last week marked one year since President Trump's "Liberation Day" - the launch of his sweeping tariff policy. The tariffs have impacted many people across the KC metro, particularly local businesses.
A key Medicare Advantage announcement is due today
Today's announcement will set the tone for how the Trump administration wants to work with private Medicare insurers.
Federal Agency Unveils Three Potential Osteoarthritis Treatments
With funding from ARPA-H, three teams of researchers have regrown bone and cartilage, even entire knees, in animal studies. Human trials are not far off.
NYC's top economic agency still leaderless under Mamdani. Business leaders are worried.
Mayor Zohran Mamdani is approaching 100 days in office. He still hasn't found someone to run the city's Economic Development Corporation.
Sportsball Monday: Giants still uneven, 49ers add WRs, Valkyries prep
We bring you up to speed on your favorite local teams.