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AI Can Spot Pancreatic Cancer Years Before Diagnosis, Study Finds
Catching this deadly disease while it's treatable can save lives.
As artificial intelligence show off diagnostic chops, scientists reckon with the way forward
On Thursday, researchers published in Science the results of a study that tested an OpenAI model on diagnostic and clinical reasoning tasks.
Can AI help doctors avoid missed diagnoses? A new study suggests yes
AI may help doctors avoid missed diagnoses, but it still needs real-world testing and human oversight before it can guide patient care.
Integrated Counselors: Bringing mental health to the physical world - Choctaw Nation of Oklahoma
Choctaw Nation Behavioral Health provides integrated counselors in clinic settings to support patients experiencing emotional distress, difficult diagnoses, or needing support during medical visits.
Brain scans reveal 3 ADHD subtypes, including a more extreme form
A study analyzing 1,154 children and adolescents breaks new ground in how to think about the growing diagnosis.
Damon Wayans reveals the scary symptom that led to his type 2 diabetes diagnosis
Damon Wayans details his type 2 diabetes journey, the symptoms that alarmed him and his new partnership to raise awareness for the diabetic eye disease DME.
Redeem the Time: What Ben Sasse Teaches Us About Life, Death, and Politics
Sasse has a lot of hard-earned wisdom to impart, including some that only comes when facing a terminal diagnosis. He’s inviting us to walk with him through that dark valley.
Astorg buys Thermo Fisher Microbiology business
Astorg has agreed to acquire Thermo Fisher Scientific’s microbiology business, creating a standalone diagnostics platform backed by private equity investment.
AI Tool May Spot ADHD Years Before Children Are Diagnosed
DURHAM, N.C. — Attention-deficit/hyperactivity disorder (ADHD) affects millions of children, yet many go years without a diagnosis, missing the chance for early support that can change long-term outcomes even when early signs are present.
'This is Me.' Autism diagnosis did not stop me from telling my story
I was diagnosed with autism at the start of sixth grade. Here's my story of how I got to journalism and now Vermont.
Early attention deficit hyperactivity disorder prediction from longitudinal electronic health records
Nature Mental Health - Using electronic health records from over 140,000 children, the authors developed a neural network model that predicts attention deficit hyperactivity disorder diagnosis...
'Who is taking care of us?': Childcare workers can't afford insurance
Andreya Chapman's job is her passion. But it's also why she's struggled to afford health coverage, an issue that pushed off a cancer diagnosis.
Ms. Rivera goes to Washington — to advocate for liver health
Through years of monitoring, a cancer diagnosis and two liver transplants, Rivera found a passion for liver health advocacy.
Timberwolves' Donte DiVincenzo reportedly diagnosed with torn Achilles, Anthony Edwards undergoing testing on knee
Brain-Gut Health Initiative supports AI-assisted diagnosis of psychiatric disorders
Psychiatric disorders affect millions worldwide, but their diagnosis still relies on clinical observation instead of standard biological tests.
Nan Schaffer, veterinarian who helped unlock the science of rhino reproduction, has died, aged 72
“One of the great tragedies of the 21st century,” Nan Schaffer once said, “will be humanity’s homogeneity.” The remark was less a warning than a diagnosis. In a world where landscapes were being simplified and species reduced to remnants, she concerned herself with what would be lost when difference itself began to disappear. For species […]
Carrie Ann Inaba shares her struggle to manage hidden, invisible illness: 'It's real'
Carrie Ann Inaba shares her silent struggle with Sjogren's disease, an autoimmune condition that she says went undiagnosed for more than 10 years.
A flawed diagnosis of Cuban health care
Progressives who praise communist systems just prove how gullible they are.
Snooki reveals regrets after cancer diagnosis (exclusive)
After being diagnosed with cervical cancer, Nicole 'Snooki' Polizzi is opening up on her big health regret.
Apex High senior makes return to soccer after cancer diagnosis
After being diagnosed with Hodgkin lymphoma her senior year, an Apex High student is back on the field — and finishing the season she once thought was over.
I was a triathlete in peak health — but my 'wavy' vision problem turned out to be something devastating
After her cancer misdiagnosis, Lucy Liu advocates for early screening
Lucy Liu shares how a misdiagnosis led to surgery and changed how she advocates for her own health.
UNE’s fourth Health Care Story Slam puts a human face on chronic illness
UNE’s fourth Health Care Story Slam on April 15 put a human face on chronic illness and the long road to diagnosis as seven speakers took the stage to explore this year's theme of balance in the Harold Alfond Forum on UNE's Biddeford Campus.
Advancing epidemic and pandemic preparedness through research readiness: SEAR Unity Studies Network Sites chart the way forward in 2026
On 25 March 2026, WHO Regional Office for the South‑East Asia Region (SEARO) convened the first meeting of the SEAR Chapter of the Unity Studies Network Meeting in 2026 to take stock of progress and plan next steps for strengthening epidemic and pandemic preparedness across the Region. The meeting focused on reviewing the ongoing adaptation of selected, standard Unity Study methodologies, sharing field implementation experiences from 2025, and identifying key priorities to guide collaborative work in 2026.Held virtually, the meeting brought together representatives from six Unity Studies network sites across five countries (Bangladesh, India, Nepal, Sri Lanka, and Thailand) as well as participants from all three levels of WHO.The meeting took place against the backdrop of ongoing regional efforts in South‑East Asia to strengthen early investigations and studies for epidemic and pandemic preparedness, with a focus on pandemic influenza and other emerging respiratory pathogens with epidemic and pandemic potential. In this context, and as part of preparedness for the rapid generation of evidence, the WHO Health Emergencies Programme in SEAR (WHE/SEAR) encourages Unity Studies sites to adapt prioritized, standardized Unity Study protocols to their national contexts. This approach supports the generation of timely and reliable evidence to inform public health decision‑making during epidemics and pandemics.These efforts are supported through a combination of experience sharing, participation in the global Unity Studies network webinars, capacity‑building of the national public health workforce, and regional collaboration that promotes inter‑country, inter‑agency, and inter‑ministerial action. In parallel, sites are encouraged to explore diversified funding sources to help sustain research preparedness over the long term.Discussions highlighted the importance of WHO’s catalytic financial support through the Pandemic Influenza Preparedness (PIP) Partnership Contributions (PIP‑PC). When combined with national and institutional resources, this support enables countries and sites to maintain continuity of activities at a core level and remain prepared to respond rapidly and effectively to future epidemics and pandemics.Regional and Global Updates: Opening the session, Dr Pushpa Ranjan Wijesinghe, Programme Area Manager, Pandemic and Epidemic Management (PEM) Unit, WHO Health Emergencies Programme, highlighted the progress made in operationalizing the Unity Studies Network across the Region and acknowledged the collaborative efforts of WHO at all three levels, together with country unity studies sites. He emphasized the availability of limited but catalytic funding through the Pandemic Influenza Preparedness (PIP) Partnership Contribution (PIP‑PC) workplan at SEARO to sustain network activities in 2026, while encouraging sites to leverage additional funding sources to expand implementation.Representing SEARO, Dr Ashok Basnet, consultant, Pandemic Influenza Preparedness reported that, at the regional level, the Unity Studies Network currently includes six sites across five countries: Bangladesh, India, Nepal, Sri Lanka, and Thailand. He noted that in 2025, catalytic funding supported protocol adaptation, training, and pilot implementation. In addition, a regional Unity Studies symposium held during the Global Public Health Summit in Sri Lanka strengthened and advocated collaboration between the Unity Studies site, national decision‑making forum, relevant technical units of the ministry of health, WHO and other partners.The symposium also highlighted the role of early investigations and studies as a key component of a multi‑source surveillance system needed at country level to generate a broad range of evidence. It underscored the critical role of country Unity Studies sites and similar research entities in generating evidence to support public health decision‑making during epidemics and pandemics.Participants of the WHO GISRS Unity Studies Sites Network- SEAR Chapter Meeting 2026 (Photo credit- PEM/WHE/SEARO). SEARO also updated participants on ongoing efforts to develop a regional Unity Studies webpage and to promote participation in global knowledge‑sharing platforms, including webinars and the WHO Community of Practice. Priorities for 2026 include supporting the implementation of Unity protocols, strengthening collaboration and experience sharing across sites, documenting and publishing findings, integrating Unity Studies activities as a component of multi-source national surveillance systems, and building workforce capacity.Dr Nickle Boddington of the Global Influenza Programme (GIP) at WHO Headquarters, which coordinates the Unity Studies Network globally, provided updates on global Unity Studies activities, noting that the network has expanded to 16 sites worldwide. New and updated protocols, including rapid clinical severity assessment tools and standardized data platforms, are being developed to support implementation. The global Community of Practice has also been launched to facilitate technical exchange, and continued support will be provided to sites for protocol adaptation, ethical approvals, and readiness for early investigation during outbreaks. Updates from Unity Studies sites in SEAR in 2025Unity Studies sites shared progress and experiences in implementing protocols across diverse country contexts. Sites initiated activities in 2025 using catalytic funding from SEARO, complemented by the mobilization of internal national resources. The Institute of Epidemiology, Disease Control and Research (IEDCR), Bangladesh, reported the adoption and piloting of investigation protocols on non‑seasonal influenza and emerging respiratory diseases during recent avian influenza outbreaks, demonstrating a multi‑source funding approach involving government, WHO and One Health partners.The Hamdard Institute of Medical Sciences and Research (HIMSR), New Delhi, India, highlighted the piloting of household transmission investigation studies, the expansion of the national Unity Studies network, and the contribution of study findings to global evidence through published outputs. The All-India Institute of Medical Sciences (AIIMS), New Delhi, India, shared experiences from large‑scale seroprevalence studies conducted during the COVID‑19 pandemic, recent efforts to strengthen national Unity network sites through training activities, and plans to initiate multi‑centre studies on respiratory viruses.Similarly, Prince of Songkla University, Thailand, highlighted its experience in developing integrated surveillance and diagnostic protocols for multiple respiratory pathogens, enhancing readiness for targeted investigations of emerging threats. The University of Sri Jayewardenepura, Sri Lanka, reported ongoing engagement with the Ministry of Health and exploration of additional funding sources to initiate studies. Meanwhile, the National Public Health Laboratory, Nepal, provided updates on continued coordination with national stakeholders to initiate implementation, despite delays related to the country context.Across sites, shared experiences underscored the importance of protocol adaptation, multisectoral collaboration, and sustainable funding to operationalize Unity Studies and generate evidence for public health action.Discussions and Way ForwardThe meeting reinforced key priorities for 2026, including strengthening unity studies protocol implementation, enhancing collaboration, knowledge sharing, integrating research as a component of national multi-source surveillance systems, and ensuring that generated evidence informs public health decision‑making. Participants also emphasized the importance of documentation, visibility, and leveraging multiple funding sources, and agreed on the following action points.Unity Studies Sites and WHO Country Offices:Advance adoption and implementation of at least one Unity protocol, continuing activities initiated in 2025 with catalytic funding, supplemented with other sources of funding where feasible.Document site-specific experiences, outcomes, and lessons learned; participate in regional and global knowledge-sharing platforms including WHO webinars and the Community of Practice.Work closely with ministries of health to establish unified national platforms for translating generated evidence into national public health decision-making. WHO Country Offices may facilitate technical support and complementary, synergistic funding opportunities where feasible. WHO Regional OfficeCoordinate with WHO Country Offices to support implementation of core unity studies activities by network sites through catalytic funding and provide technical guidance and virtual engagement opportunities throughout 2026.Facilitate the participation of all Unity Studies sites in the regional meeting on Unity Studies implementation in October 2026, to be held back‑to‑back with the Annual SEAR Regional PIP‑PC Meeting; develop and host a SEAR Unity Studies website; and mobilize support from academic institutions within the SEAR Unity Studies Network to support the development of regional manuscripts that showcase Unity Studies activities to scientific audiences and promote knowledge‑sharing.Explore complementary funding opportunities and partnerships to sustain and expand network activities across the Region.WHO HeadquartersProvide global technical guidance, updated protocols, and toolkits to support the implementation of Unity Studies in SEAR.Facilitate engagement of SEAR sites in global webinars, the Community of Practice, and opportunities to showcase their work.Support joint publications, inclusion of SEAR experiences in global outputs, and identification of additional funding and collaborative opportunities to strengthen Unity Studies activities.
Cancer
WHO fact sheet on cancer providing information on the health burden of different types of cancer, causes, risk factors, prevention, early diagnosis, treatment, palliative care, and WHO's work in this area.
Radiology Business Management Association elects new board members
Stacy Sanso—director of patient access for ARA Diagnostic Imaging, the Austin, Texas, affiliate of Radiology Partners—takes over as president of the association.
Re:Cognition Health Delivers Landmark International Clinical Trial to Explore Whether a Simple Finger-prick Blood-based Biomarker Test Can Provide Earlier Alzheimer's Diagnosis
Re:Cognition Health, a global leader in new treatments for Alzheimer's Disease, is delivering an international clinical trial to evaluate whether a simple finger-prick blood test can revolutionize how Alzheimer's disease is diagnosed. Compared with the current invasive and expensive diagnostic methods, this approach could provide a scalable solution for an earlier, easier, more accurate, affordable, and accessible diagnostic method. Re:Cognition Health will help enroll approximately 1,000 partic
Radiology Business Management Association names new board of directors
Stacy Sanso—director of patient access for ARA Diagnostic Imaging, the Austin, Texas, affiliate of Radiology Partners—takes over as president of the association.
After his own diagnosis, New Orleans Broadway star starts foundation for children with Type 1 diabetes
Kyle Banks was diagnosed with Type 1 diabetes during his Broadway tour of Disney's The Lion King after months of struggling with symptoms. Now, the New Orleans native wants to give back to his roots by providing resources for Louisiana children and families living with the disease.
A new way to detect life beyond Earth without knowing what life looks like
Researchers from the Earth-Life Science Institute (ELSI) and National Institute for Basic Biology have developed a new method to detect extraterrestrial life without relying on traditional biosignatures. By modelling how life might spread between planets, they demonstrate that life could be detected through statistical patterns across planetary populations rather than on individual planets. This "agnostic biosignature" approach could assist in guiding future searches for life beyond Earth.
ESPN's Dick Vitale announces he's been diagnosed with cancer for a fifth time
"I'm four for four and I'm fully confident I'm going to make it five for five."
Dick Vitale health update: College basketball analyst confirms melanoma diagnosis
ESPN college basketball analyst Dick Vitale shared another health update on Monday in which he announced he was diagnosed with melanoma.
No Doubt guitarist Tom Dumont reveals early onset Parkinson’s diagnosis
The announcement comes just one month before the band is set to reunite for a residency at The Sphere in Las Vegas beginning May 6.
Longtime WDIV sports reporter Jamie Edmonds reveals breast cancer diagnosis
Longtime WDIV sports reporter Jamie Edmonds revealed Monday morning that she has been diagnosed with breast cancer.
USC Brain Health Center could be hub for Alzheimer’s treatment, new tech for mental health
A new $30 million Brain Health Center at USC in Columbia will be a magnet for advanced diagnosis and treatment of Alzheimer’s disease and dementia but also deploy new technology for mental health.
No Doubt guitarist Tom Dumont reveals early-onset Parkinson's disease diagnosis
No Doubt guitarist Tom Dumont reveals that he's been diagnosed with Parkinson's, one month before the band is set to reunite for their Las Vegas residency at the Sphere.
Woman, 26, Had Excessive Itching but Was Told 'It's Just One of Those Things.' She Then Self-Diagnosed Her Cancer (Exclusive)
A young woman suffered from excessive itching and was dismissed by multiple doctors, before she eventually self-diagnosed herself with cancer. Sumbul Ari recalls her health journey in an exclusive interview with PEOPLE.
Deion Sanders says he's in good health during Colorado's spring game
A year after being diagnosed with bladder cancer, Deion Sanders insists he's in good health.
Deion Sanders back on the field at Colorado's spring game
After a season that saw Colorado go 3-9, Buffaloes coach Deion Sanders, 58, was hands-on as he watched his team scrimmage on Saturday at the spring game, telling reporters that "I'm good, I'm good," after being diagnosed with bladder cancer last year.
These women had their breasts removed to thwart cancer. Then came the pain.
Many women are afflicted by post-mastectomy pain syndrome, which spans from uncomfortable to disabling and can last years. It’s inconsistently diagnosed and treated, leaving some women in agony as they hunt for relief and struggle to find doctors who take their pain seriously.
13 years ago, a young Rostraver mom prepared to die; the ‘super responder’ now shows no signs of cancer
In 2013, 28-year-old Kate Crawford threw herself into preparing for her death. She had a fresh diagnosis of metastatic breast cancer, an estimated 18 to...
Kansas City health leaders announce new integrated theranostics research and treatment center
The center will unite diagnostics, molecular imaging, radiopharmaceutical production and targeted therapies under one coordinated platform.
G7 One Health Summit launches global diagnostics initiative, and other health stories
Top health news: G7 launches global diagnostics initiative; Five actions to end tuberculosis; Middle East conflict impacts healthcare.
HGTV’s Jenn Todryk Shares Positive Health Update With Fans
Todryk has been diagnosed with hyperthyroidism and Hashimoto's disease for several years.
HGTV’s Jenn Todryk Shares Positive Health Update With Fans
Todryk has been diagnosed with hyperthyroidism and Hashimoto's disease for several years.
‘Live’ Emcee Déjà Vu Shares Update on Recent Health Diagnosis
The TV personality sported a face mask during the show's Tuesday, April 7, episode.
Chicago Bears HOFer Steve McMichael diagnosed with CTE year after death
McMichael died in April 2025 following a 5-year battle with ALS.
Health Law Navigator: The Compliance Department vs. The Machines: A Playbook for Using AI
In 2026, health care facilities are under relentless pressure to use AI. From diagnostic algorithms that outperform radiologists to predictive
Diagnosis for 4.6.26: Checking the pulse of Florida health care news and policy
Caregivers power Florida economy amid legal battles and health care innovation
Terry Crews' Wife, Rebecca, Reveals Parkinson's Diagnosis, Had New Treatment: EXCLUSIVE
She's sharing her diagnosis publicly for the first time after undergoing an exciting new treatment procedure.
Siemens Healthineers Diagnostics Review Puts Valuation And Business Mix In Focus
Siemens Healthineers (XTRA:SHL) is reviewing options for its Diagnostics business, including a possible sale. The review follows moves by Siemens AG to reduce its majority stake in Siemens Healthineers. Any decision could reshape the company’s business mix within the global healthcare diagnostics market. Siemens Healthineers operates across imaging, diagnostics and related healthcare technologies, giving it a broad role in hospital and lab workflows. A potential change in the Diagnostics...
Scientists discover hidden gut signals that could detect cancer early
A new study reveals that gut bacteria and metabolites may hold the key to detecting serious digestive diseases earlier and more easily. Using AI, scientists found that biomarkers linked to one condition can often predict others, showing these diseases are more interconnected than previously thought. This cross-disease insight could lead to faster diagnoses without invasive procedures.
We all need to become better science storytellers. Here’s why and how.
Last week, in a lovely New Haven bar, six people gathered in front of a crowd to tell stories that were somehow related to science and public health. It was magical. One person talked about learning how social determinants of health helped them forgive their mother’s alcoholism. Another shared what it’s been like navigating a dementia diagnosis. Another described their last dinner with their mother before they left Nigeria to come to the U.S. and how that moment, plus the diagnosis that followed, shapes their career goals today. As the Executive Director of The Evidence Collective at Your Local Epidemiologist, I was ecstatic to bring this event, “Science and Storytelling,” to the community surrounding the Yale School of Public Health. Stories are not the default way most people communicate about science and public health. In fact, we are taught to take all the emotion out of data, but that makes it pretty darn boring to everyone else. And if people can’t see themselves in it, feel themselves in it, or influence it, how can we ask them to support it? Why do stories stick? How can we all—from community members to public health scientists—do better? And what are some examples?
Certain radiology subspecialties less likely to score promotions than others
In particular, rads working in breast imaging and pediatrics appear to score the lowest rates of career advancement, experts write in Current Problems in Diagnostic Radiology.
CDC pauses dozens of types of lab testing during evaluation and in wake of downsizing
The federal government’s disease-tracking agency has paused its diagnostic testing for rabies, monkeypox and a number of other infectious diseases.
Why AI health chatbots won’t make you better at diagnosing yourself
A chatbot might know what’s wrong with you, but when people try to use them to understand symptoms, they may end up no closer to the answer.
Why People With Chronic Illness Are Turning to AI Chatbots for Health Advice
Some women with complex chronic illnesses are using chatbots to search for diagnoses or relief from their symptoms.
Céline Dion Announces Comeback Concerts After Health Struggles
Music icon Céline Dion shared a surprise video message on her 58th birthday that she’s returning to the stage with ten concerts planned in Paris. Fans are celebrating her long-awaited comeback after she stepped away from performing back in 2022 when she was diagnosed with a rare neurological condition called “stiff person syndrome” which can cause muscle rigidity and painful spasms. NBC’s Emilie Ikeda reports for TODAY.
He was headed to medical school orientation. Instead, doctors found a brain tumor.
This 24-year-old was about to start medical school. Instead, a visit to the ER down the street turned into a brain tumor diagnosis.
St. Tammany Health System offering prediabetes program
Covington resident Ruth Stickler resolved at the start of the year to return to healthier lifestyle after some stressful times led to a diagnosis of prediabetes. But she questioned how
Tala Health Launches With $100M to Transform Patient Care Through AI Collaboration
Based in San Francisco, the company is developing a platform that integrates AI copilots throughout the entire patient experience, from initial intake and diagnosis to follow-up and long-term management.
Celine Dion announces comeback concerts September-October in Paris
Céline Dion will perform at in Paris in September and October, marking her return to the stage after her diagnosis with stiff-person syndrome.
Music therapy brightens chemo visits for 3-year-old at Corewell Health in Royal Oak
Three-year-old Carson Jamo, diagnosed with leukemia in June 2025, regularly visits Corewell Health in Royal Oak for chemotherapy, where music therapist Brandon Banas helps transform challenging appointments into positive experiences.
When a parent has cancer, this UNC Health tool helps guide conversations with kids
A North Carolina mom diagnosed with breast cancer at age 38 shares how she navigated telling her children. Now, a new UNC Health tool is helping more families have those difficult conversations.
Concrete’s distinct microbial zones could change how building health is assessed
Concrete harbors distinct microbial zones whose signatures survive the heat of routine core sampling, a discovery researchers say could one day put structural health diagnostics within reach of general maintenance staff and even residents.
5 Founders Who Built Businesses From Their Hardest Moments
These 5 founders started with a repossession, a rejection, or a diagnosis. What they built next is worth knowing about.
Gary Woodland grabs emotional first PGA Tour win after brain surgery, PTSD diagnosis: 'Just keep fighting'
"I’ve got a big fight ahead of me, and I’m going to keep going. But I’m proud of myself right now.”
Mom, 36, Had Health Symptoms Dismissed for Years. Then, She Was Diagnosed with One of the World’s Rarest Cancers (Exclusive)
A woman was diagnosed with one of the world’s rarest cancers, neuroendocrine cancer, after her health issues were dismissed over the years by multiple different types of doctors. Ashleigh Smith, a mom of two, worked a second job as a food delivery driver to help raise funds amid rising costs tied to her cancer treatments, she tells PEOPLE exclusively.
Anderson Cooper Details His Dyslexia Diagnosis as He Blasts ‘Cruel’ Trump
The CNN anchor calls the president 'ignorant' for his recent comments.
Ipswich paramedic died after struggling with her mental health
A coroner says Rebecca McLellan, from Ipswich, struggled after her bipolar disorder diagnosis.
Mass. woman diagnosed with Alzheimer's in 30s told 'too young' for drug by insurance
A Massachusetts woman with early onset Alzheimer's fought her insurer over a denied treatment, raising questions about age limits and access to care.
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Breathing easy: prioritising respiratory health for older adults in Asia Pacific
Highlights the growing burden of respiratory disease in ageing societies and calls for greater attention, outlining actions for earlier prevention, diagnosis and care in Asia Pacific.
Warriors' Moses Moody reportedly diagnosed with torn patellar tendon after being stretchered off vs. Mavs
Moses Moody went up for a breakaway dunk, but his left knee gave out in the final minute of overtime on Monday night.
Marathon has sold 1.2M copies across Steam, PS5, and Xbox
Alinea Analytics estimates show that Marathon has generated gross revenues of $55M via 1.2M copies sold on Steam, PS5, and Xbox: Looking at the split between Steam, PS5, and Xbox, Steam is clearly the main platform for Marathon, accounting for a little under 70% of the audience (800K copies sold). Meanwhile, PS5 takes about 19% (217K) and Xbox (including console, PC, and cloud) accounts for a bit over 11% or 133K. Marathon is technically a first-party Sony title, so seeing the home console struggle to break 20% of the volume is a notable data point for the ongoing platform-agnostic debate. PlayStation Studios online games will almost certainly continue being multiplatform (despite Sony reportedly pulling back on PC releases). Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe As for Marathon, the consensus among hardcore players who pushed through the awkward onboarding phase – myself included – is that it’s fantastic. The gunplay, aesthetic, and presentation are among the best in the shooter genre. A great game doesn’t always equal an immediate hit, though, as shown by our estimates. Things are looking lukewarm right now. But this might be one of those marathon-not-a-sprint situations. Had to, didn’t I? Why wasn’t Marathon a hit on the same level as Arc Raiders? One topic that came up in a lot of conversations at GDC this year was why Marathon hasn’t hit the same stratosphere as Arc Raiders. On paper, they’re both extraction shooters, and Marathon has the Bungie pedigree – the house that built the gold standard for gunplay in Halo and Destiny. Marathon’s neon-futuristic aesthetic also distinguishes itself from the gritty realism of Tarkov or the post-apocalyptic hope of ARC Raiders. But vibes can only get you so far for first impressions if the onboarding feels like a brick wall. Marathon is a sweaty PvP-focused experience with a first-time user experience and UI that I can only describe as dreadful. Players are dropped into a complex ecosystem where the UI, though visually striking, is functionally uninformative, forcing users to manually hover over nondescript, identical icons just to identify basic gear or weapon mods. This lack of clarity is compounded by punishing mechanics like a severe heat gauge for movement and a scarcity of vital resources, all without a clear tutorial or a low-stakes mode to learn the ropes. Most people – even top streamers and veteran shooter players – have no idea what’s going on in Marathon at first. Arc is on the complete other end of the spectrum. As we covered here and here, Arc Raiders offers a more collaborative, approachable loop where players often work together toward shared goals. And the objectives are instantly clear. To many players, this contrast only emphasised Marathon’s issues, especially during the testing period. Players understand the Arc Raiders loop within 30 minutes, while Marathon acts as a massive filter, chewing up newcomers and spitting them out before they can experience the depth of Bungie’s signature gunplay. What I’m getting at here is that the poor first-time user experience of Marathon’s Server Slam likely stifled launch sales, while the opposite was true for Arc. Let’s look at the pre-launch copies sold for each game during their respective Server Slams (launch-aligned) : Looking at the trajectory: Arc Raiders saw a massive 80% jump in copies sold during its three-day Server Slam (day -13 to -11). Players jumped in, realised the water was fine, and immediately opened their wallets. Marathon, meanwhile, saw a 49% increase in the four days following its Slam (Day -7 to -3). At the time of each game’s respective launch, Arc Raiders had nearly double the Steam footprint of Marathon – and word of mouth only continued to grow. Bungie could have had more time to fix the onboarding process had the beta happened earlier. But Marathon launched three days after the beta finished. These factors limited the launch sales quite a bit, I reckon. Marathon has found a niche audience, though Despite the friction-heavy start, the data suggests that those who survived Marathon’s onboarding are loving life. We’ve been tracking cross-platform DAUs, and while there’s the expected post-launch leakage, many players are sticking with it. After peaking at 478K total DAUs on its first Saturday, Marathon has settled into a respectable rhythm, holding 345K DAUs as of yesterday and averaging 380K DAUs across the weekend. Steam continues to do the heavy lifting here, consistently accounting for the lion’s share of the daily players. Players have been putting in the hours, too: On Steam, Marathon’s average playtime has climbed to 27.8 hours, significantly outpacing the console averages on PS5 (16.5h) and Xbox (17.3h). Even more telling than the averages: 22% of the Steam audience has surged past the 50-hour mark, and nearly 7% have already logged over 100 hours. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe This data suggests that once the Bungie magic clicks, it hooks players deeper than the average extraction shooter. There’s also started to be a shift in the game’s discourse. Marathon launched as one of those games that’s cool to hate. But as Marathon’s 100-hour club grows, we’re seeing conversations around its mechanical merit outweigh the negativity. Several high-profile creators, who were initially vocal critics, have spent the last week coming around on the mechanical depth of the endgame. It’s a subtle but positive signal; the hate train is losing steam, and a new narrative about the game is emerging. Bungie faithfuls unite Another interesting metric in Marathon’s first few weeks is who, exactly, is playing. Bungie leans heavily on its prestige as the “makers of Halo and Destiny,” in its marketing, and that message has clearly hit the mark. On Steam, the gravity (hammer) of Bungie’s previous work is unavoidable. A staggering 78.2% of Marathon players also played Destiny 2. The trend carries across other platforms, with 74.2% of PS5 players and 82.7% of Xbox players also having played Destiny 2. The Halo legacy lives on, it seems. More on that in a bit. While Destiny 2 went free to play, these numbers still represent a high-intent migration of a fanbase that trusts Bungie’s specific brand of kinetic gunplay and cryptic world-building. The Xbox data adds another layer of legacy. About 85.7% of Marathon players on Xbox have played Halo Infinite, while over half of the Steam audience has spent time in Halo Infinite and 36.1% in the Master Chief Collection (a paid collection of the old Bungie-made legacy games). Interestingly, we see a 55.9% overlap with ARC Raiders on Steam. Overlap is even higher there on PlayStation (60.5%) and Xbox (66.5%). And there’s also significant crossover with Helldivers 2 on all platforms, too. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe Bungie has found some of its fans with Marathon, and the challenge now is keeping this engaged in a high-stakes PvP environment when they’ve spent the last decade primarily enjoying the power fantasies of PvE. On that note… Go the full 26 miles? Or cut and run? Time for some could’ve, should’ve, would’ve. These things would have improved Marathon’s performance at launch: A more robust onboarding process, perhaps in the form of a short single-player/PvE campaign. We know Bungie fans love this stuff. A traditional arena-based mode akin to Destiny’s Crucible could have been a bridge for the cautious players who’d have been otherwise deterred by the Server Slam. It’s also a great palate cleanser after getting merked. Introducing a dedicated PvE environment would have similarly diversified the conversation and lowered the barrier for the Bungie faithful who found the pure PvP extraction loop too abrasive. PvE is safer than PvP these days. There’s an argument that a thin PvE mode would have just felt like a budget Destiny, potentially hurting the brand more. But given how dire the FTUE is, I think it would have been a net positive. Any kind of tutorialised loop that demystifies the stakes, really. While there is merit in a studio sticking firmly to a singular creative vision, and going all in on the hardcore extraction loop. Less forgiving is the technical reality is that the user interface and first-time user experience (FTUE) were not at a commercial standard for launch. Subscribe for free to get the most accurate games estimates in your inbox twice a week 🫶 Subscribe In a landscape where player time is oversaturated and the most contested currency, a flawed FTUE is a critical failure point. But it’s not all doom and gloom, as Marathon has an incredible, unique gameplay loop, suggesting that financial success is still attainable if Bungie can pivot effectively. Bungie and PlayStation now face a difficult strategic crossroads, though – one within a challenging games market. They could: Double down on Marathon with a long-term Rainbow Six Siege- or No Man’s Sky-style recovery plan, which is something I heard Last Stand Media’s Chris Maldonado mention last week. While this could be a sunk-cost fallacy in action, it could eventually yield the audience the game’s mechanical depth deserves. Shift focus toward the inevitable Destiny 3 or another project, mitigating the escalating opportunity cost and cutting their losses, so to speak. Doing both is an expensive proposition, given the high overhead and burn rate of operating out of Bellevue, Washington. With Sony recently demonstrating a lower threshold for underperforming studios and projects, the margin for error has vanished. Whatever happens, the next six months will determine whether Marathon becomes a cornerstone of Sony’s live-service portfolio or a cautionary tale of vision exceeding accessibility. I’m hoping it’s the former, because Marathon rocks. As always, hit subscribe to get updates on Marathon and other relevant games. Subscribe Want to get your hands on our data for yourself – for free? We’re offering a free trial of our platform for games companies. Send us a message here, or reply to this email, and we’ll set you up. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
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