SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " dj " 2,347 found 🔀 AI-powered Shuffle
Lessons from Chinese business leaders about integrating AI in the workplace
China's experience in moving from AI adoption towards durable productivity – in three distinct stages – offers a blueprint for the rest of the world
Jamie Foxx says he asked Quentin Tarantino to cut rape scene in ‘Django Unchained’ to ‘protect’ Kerry Washington
Jamie Foxx says he asked ‘Django Unchained’ writer-director Quentin Tarantino to cut a rape scene in the 2012 film to ‘protect’ Kerry Washington ahead of her ‘Scandal’ breakthrough.
Analysis | Alaska’s weird (and important) Senate race
There will be two Dan Sullivans on the ballot, which greatly benefits Democrats.
Walter’s TWG hits back at fraud claims, says it has no victims
TWG Global, the holding company at the heart of Mark Walter’s empire, hit back against what it called “multipronged attacks” on its business as prosecutors continue to probe the firm.
Alpharetta Mall May Convert to Mixed-Use Entertainment Center
The North Point Mall may be transformed into a sports-adjacent, mixed-use entertainment center. In a major move for professional sports in Georgia, the Alpharetta City Council voted to approve a vision to transform North Point Mall into a sports-adjacent, mixed-use entertainment district. Its all contingent on the NHL awarding a franchise team to the North Point ...
Alleged Foldable iPhone Motherboard Photos Surface Online
Images and video claiming to show circuitry from Apple's upcoming foldable iPhone are circulating on X and Chinese social media platforms. For example, on X, the user "LusiRoy7" posted a short video alongside an image, as well as a labeled composite image identifying components, purportedly depicting the motherboard of Apple's foldable iPhone. The image appears to show the CPU, a hinge connector, a flex cable connector, and more.
907 Sports: The northernmost football field in U.S. may need to be replaced soon
In this edition of 907 Sports, we speak with Barrow administrators about the eventual replacement of the football team’s iconic blue turf after nearly 20 years in the elements. Plus, we learn about the northernmost pep band in the U.S. and recount the trip to Utqiagvik from searching for polar bears to a polar bear plunge in the Arctic Ocean.
Finns may live to 80 or 85, but productive healthy years average 43 to 46
For the first time in Finland, population-level norm values have been established for estimating life expectancy adjusted for health-related functional capacity and productivity. The new study provides ...
Rewriting the Vaccine Schedule Without Science at the Table
Dr Daskalakis explains the confusion a recent executive order on vaccines can wrought, and why the MMR vaccine cannot simply be split into three shots.
Out of the Lab: Business Course Gives Scientists Opportunity to Explore Entrepreneurship - Polsky Center for Entrepreneurship and Innovation
The Entrepreneurship for Science and Medicine course gives University of Chicago graduate students, postdocs, and faculty the opportunity to explore the intersection of science and business. Taught by Chicago Booth School of Business Adjunct Professor of Entrepreneurship Robert Altman, MBA ‘88, and offered in partnership with the Polsky Center, the course examines how scientists can
Out of the Lab: Business Course Gives Scientists Opportunity to Explore Entrepreneurship - Polsky Center for Entrepreneurship and Innovation
The Entrepreneurship for Science and Medicine course gives University of Chicago graduate students, postdocs, and faculty the opportunity to explore the intersection of science and business. Taught by Chicago Booth School of Business Adjunct Professor of Entrepreneurship Robert Altman, MBA ‘88, and offered in partnership with the Polsky Center, the course examines how scientists can
North Carolinians Continue to Trust Elections Close to Home More Than Elections Across the Nation, Catawba College-YouGov Survey Finds
Catawba College is ranked #4 among the best colleges in the South. Located in historic Salisbury, NC, it is a private, coeducational liberal arts college established in 1851. Our mission is to enrich the educational experiences of students and to prepare them for productive, meaningful lives of purpose. Our campus consists of over 30 buildings on 276 acres, a beautiful blend of neogothic architecture set on a shaded hillside adjacent to its own ecological preserve. We are just two hours from the Appalachian Mountains and four hours away from some of the best beaches on the Atlantic Coast.
Orioles news: Kicking off a nine-game road trip
Beavers’s adjustment, hope in the minors, and more in today’s Bird Droppings
Air taxi vertiport coming to downtown LA sports complex
Archer Aviation, the official air taxi provider for the 2028 Olympic Games in Southern California, adds the venue to its network of flight facilities in the region.
US lawmakers question Health Secretary Kennedy on vaccine settlement disclosures
A group of U.S. senators said Health Secretary Robert F. Kennedy Jr.'s recent explanation for how he disposed of a financial stake in litigation involving Merck's Gardasil vaccine conflicts with earlier answers he gave in written testimony and federal ethics filings, a letter reviewed by Reuters shows.
Yankees news: Some thoughts about Spencer Jones
Spencer Jones has been making some adjustments at the plate; Aaron Judge, Giancarlo Stanton see HOF candidacies weakened.
Paraguayan doctors launch a five-day national strike amid a collapsed health system
Paraguayan doctors started a five-day national strike on Monday to demand better working conditions, pay adjustments, and more medical supplies amid a worsening health crisis in the South American country, where seven out of ten people rely on public healthcare.
AMC Entertainment Holdings (AMC) Could Be 2% Undervalued Following Governance Changes
Governance changes at AMC Entertainment Holdings AMC Entertainment Holdings (AMC) has put forward several corporate governance changes for a stockholder vote at its September 24, 2026 annual meeting, aiming to adjust how its board and investors share decision making power. See our latest analysis for AMC Entertainment Holdings. Alongside these proposed governance changes, AMC Entertainment Holdings has seen a 67.92% 90 day share price return and a 65.84% year to date share price return, while...
Bronzeville development site pitched for Pete’s Fresh Market
The proposal for the former public housing site Stateway Gardens would bring a long-awaited grocery store to the neighborhood, with about 500 residential units planned for a later phase.
Hundreds gather in Tuscaloosa for statewide behavioral health conference
Organizers said more than 500 people attended the conference either in person or online.
Archer Aviation plans downtown Los Angeles vertiport at L.A. LIVE entertainment district
Archer Aviation and AEG have announced plans to develop a vertiport at L.A. LIVE, AEG's sports and entertainment district in downtown Los Angeles adjacent to Crypto.com Arena, with Archer as the distr
Discover the team sports to watch at the Dakar 2026 YOG
As the first Olympic sporting event to be held in Africa, the Dakar 2026 YOG will bring together the world’s best young athletes in Senegal from 31 October to 13 November 2026. Discover four team sports in the official competition programme: Baseball5, futsal, rugby sevens and 3x3 basketball.
Tattooed Mom works to bring live performances back after licensing violation
The longtime South Street bar is adjusting its events while its owner navigates city licensing requirements.
California’s clashes over business regulation rage on as legislative session nears end
As the Legislature approaches the August 31 adjournment of its two-year session, some of the bills arising from the conflict are still pending, and the contending forces are applying maximum pressure to affect the outcomes.
The health of Norway's King Harald deteriorates over the weekend
King Harald of Norway’s health has deteriorated, according to the royal palace
Madison back-to-school Free Haircutz event pairs style with health services
Families packed the Alliant Energy Center for the 18th annual Back to School Free Haircutz event.
Call of Duty: Modern Warfare 4 Beta Struggles To Impress
With more competition than ever, the once immovable military shooter is going to have to earn its stripes, though some fans feel Infinity Ward's adjustments might be over-corrections
Synthetic everything is warping America
It's poisoning the signals people rely on to understand reality.
GCC Patch Adjusting AMD Zen 5 Misprediction Cost Nets 12% Win In Benchmark
An AMD compiler engineer posted a patch on Saturday for the GNU Compiler Collection (GCC)
Tennis in 2026 is a reminder of what Williams, Federer, Nadal and Djokovic made the sport forget
The dominant players that came before the current stars of tennis made the extraordinary appear routine. It's not so easy.
Norman Knight: Science fiction birthday twins
Editor’s note: Opinion pieces are solely the opinion of that person and not the Daily Journal.
GPL Column: Make a difference with citizen science
Editor’s note: Opinions expressed by columnists are solely the opinion of that person and not necessarily the Daily Journal.
Montgomery County woman dies from West Nile virus, health officials confirm
A Montgomery County woman in her 90s has died from West Nile virus, marking the county’s first confirmed death from the mosquito-borne illness in 2026, health officials said.
Meet the scientists 3D printing corneas to restore people's vision, potentially filling a worldwide shortage of transplantable tissue
Corneal blindness affects millions of people globally, but donor tissue for transplants is in short supply. These researchers believe that 3D bioprinting can help close that gap.
Opinion | Boston's racial wealth gap is as glaring as ever
Home and business ownership, and the generational wealth they provide, are the only way out.
Science meets art in unique Woodside artist residency
Annual Leonardo@Djerassi program fosters interdisciplinary inspiration and collaboration at famed mountain ranch, where everything from the fog to the forests can play a role in artists' works.
Genki’s new customizable controller has a big screen and adjustable buttons
A controller that prioritizes personalization.
Cook Political Report shifts Senate races in Texas, Iowa leftward to ‘Toss Up’
The nonpartisan publication moved its ratings in four contests to the left.
Cameroon's President Biya returns after a long stay abroad raises health concerns
President Paul Biya has returned to Cameroon after more than two months abroad.
Cameroon's President Biya returns after a long stay abroad raises health concerns
President Paul Biya has returned to Cameroon after more than two months abroad.
IRS Updates Business Interest Deduction Guidance Following Tax Law Changes
Revised FAQs for the business interest deduction explain changes to adjusted taxable income, floor plan financing, capitalization rules, and CFC inclusions.
Alessi-Miceli: Workforce development is everybody’s business
HIA-LI and partners launched LongIslandJobs.org to connect businesses, educators, and job seekers, addressing workforce development challenges on Long Island.
I bought DJI’s banned camera — it was cheap and easy
I now own a DJI Pocket 4 Pro, and I didn’t even have to smuggle it into the US.
Astronomers spot the closest, fastest star ever seen orbiting our galaxy's monster black hole
A star is whipping around the Milky Way's central black hole incredibly fast, setting a record for the tightest orbit ever observed
With help from KEXP DJ, Seattle musician releases vinyl album
Tinsley hadn't planned to record a debut album, let alone release one in a physical format. With some help from John Richards, that dream became reality.
Pollen has a surprising problem — and honeybees have found a way around it
Honeybees can apparently detect when their food has the wrong balance of essential nutrients and adjust how much they eat to avoid potentially harmful excesses. They also transform pollen into remarkably well-balanced “baby food” for their larvae, revealing a sophisticated nutritional strategy hidden inside the hive.
Lauren Alaina, Tyler Hubbard, Corey Kent highlight 2026 Peanut Festival entertainment
Three iconic country acts will take the main stage at this year’s National Peanut Festival, as Dothan’s signature area event announced their entertainment and events calendar for this year’s festival.
‘The adjustments no longer reflect a change in responsibility’
Opinion, comment and editorials of the day
Can the existence of an afterlife be proven? The scientists looking for God
There are doctors, neuroscientists and physicists who believe science can prove life after death, although for most this remains a matter of faith rather than laboratory work
Could GLP-1s help treat opioid use disorder? Vanderbilt Health study now enrolling
The study, Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder (TAB), is a double-blind, randomized, placebo-controlled trial conducted through the National Institute on Drug Abuse’s Clinical Trials Network.
Get closer? Aurora looks at when to tell neighbors about new business development
"We have heard a lot from folks who are not adjacent property owners who feel like 'Oh, this just got thrown down in my community and no one was going to tell me anything about it'"
Mississippi weighs three-year short-term health plan as coverage drops
One-year short-term plans are already available. The state is working on a three-year option through an online portal where people could compare doctors, drugs and provider networks.
🚨 Official: Le Mans sign a 2018 World Cup winner!
The last dance?It’s official: Djibril Sidibé is joining Le Mans for two seasons!The 2018 World Cup winner signed with the newly promoted Ligue 1 side this Tuesday morning.After two seasons with Tou...
Developers secure construction financing for Neyland Entertainment District
Arctos, RVX Ventures, and Magellan Development have secured an undisclosed amount of construction financing for the Neyland Entertainment District that will be built adjacent to the University of Tennessee’s Neyland Stadium.
‘There is nothing else’: Californians face eviction as insurer cancels assisted living benefit
Thousands of California families are facing abrupt cancellations of coverage for assisted living as insurer Health Net adjusts the benefits it provides.
In Florida, Wasserman Schultz sparks a debate over what representation means in diverse districts
Rep. Debbie Wasserman Schultz is running for reelection in a new Florida district after Republicans redrew the congressional map.
In Florida, Wasserman Schultz sparks a debate over what representation means in diverse districts
Rep. Debbie Wasserman Schultz is running for reelection in a new Florida district after Republicans redrew the congressional map.
Bob on Business: Retail sets up shop in North Main project between Stockyards, Panther Island
Also, Alliance acquisition; heavy lifting; Arlington’s BIRD;Hillwood looks north; and water, water not everywhere.
Growing threat to free speech: Bogus copyright claims are making political stories disappear
Google’s removal of stories underscores mounting concern that federal copyright law is being used by people relying on automated, AI-driven and anonymous complaints to file fraudulent takedown notices, all in the name of suppressing headline news.
Novak Djokovic Reveals Concerning Health Issue, Makes Telling Admission About Future
Novak Djokovic revealed a longtime health issue after his Cincinnati Open upset loss and made a telling admission about his playing future. The post Novak Djokovic Reveals Concerning Health Issue, Makes Telling Admission About Future appeared first on HEAVY.
Novak Djokovic reveals unspecified health issue following ouster at the Cincinnati Open
The tennis star struggled through a match, ultimately losing in the second round to a 25-year-old Argentine player.
Novak Djokovic reveals ongoing health condition after defeat in Cincinnati
Novak Djokovic took a medical break after a gruelling 18-minute hold before losing 2-6, 6-4, 6-4, with the 24-time major champion later revealing that a health condition was behind the decision; The US Open is live on Sky Sports from August 30
Novak Djokovic Reveals He’s Been ‘Dealing With (A Health Issue) For Many Years Now’
The 24-time major champion got down on his knees on the court and later appeared to vomit into a towel during his 2-6, 6-4, 6-4 loss to Argentina’s Thiago Agustín Tirante
“I Have A Lot Of Problems”- Novak Djokovic Opens Up About Health Struggles In Heat After Shock Cincinnati Open Exit
The sweltering heat of Ohio has put an end to Novak Djokovic’s Cincinnati run, but losing the match is just one part of the story. The Serb has now revealed that an underlying health issue, which gets worse during humid conditions, was the real factor behind his untimely demise from Cincinnati.
Djokovic feels the heat in Cincinnati opening defeat
Novak Djokovic suffered in the second set from punishing heat and humidity on Saturday but made a match of it before falling 2-6, 6-4, 6-4 to Argentine Thiago Tirante in what could be the Serb's last appearance at the ATP-WTA Cincinnati Masters. Martin Landaluce beat Matteo Arnaldi 6-4, 4-6, 6-4 to reach a third-round clash against Tirante.
WTAP + | Mid-Ohio Valley man takes a chance by starting business
Mid-Ohio Valley man says he took a chance on himself by opening up his own business.
Unexpected consequence of Seattle-area lax return-to-office mandates
As tech companies in Seattle examine their budgets, some adjustments exclude the local business partnerships that have existed in their offices for years.
Paul Finebaum Blasts Commanders’ Jayden Daniels Over LSU Rift
Washington Commanders quarterback Jayden Daniels is at odds with the LSU Tigers football program after the school gave his former No. 5 jersey to sophomore cornerback DJ Pickett. Daniels wore No. 5 during his time with the Tigers and became the program’s third Heisman Trophy winner in 2023.As a result, Daniels’ attorney sent a cease-and-desist […] The post Paul Finebaum Blasts Commanders’ Jayden Daniels Over LSU Rift appeared first on HEAVY.
Nancy Cartwright, philosopher: ‘People distrust science because they feel the system has abandoned them’
The thinker reflects on evidence-based science and advocates for combining methods to put research to good use in economics or public health
Josh Allen and DJ Moore show signs of bringing back big-play dimension
In a crowd-buzzing moment, one play represented why the Buffalo Bills acquired Moore in trading a second-round pick to the Chicago Bears in March.
FBI seized devices from Guggenheim CEO Mark Walter, top deputy: report
Federal scrutiny of the Chicago-based investment giant reached Walter and Guggenheim President Dina DiLorenzo months before Walter struck a $12.5 billion deal to sell the Lakers.
One UI 9.5 leaks continue: Samsung eyes a glass UI with shiny edges and 'depth'
Think Liquid Glass.
National Science Foundation reverses $1 million cut to CU Boulder quantum center
“That was a very big relief, actually,” co-director of the Physics Frontier Center Andreas Becker said. “We were trying to work through this already and how we could adjust and mitigate the impact on the research and the…
Mass fish necropsy helps forecast salmon returns in Oregon
Scores of volunteer scientists performed a mass fish necropsy in Newport last month. Events like this help forecast salmon returns, as climate change has upended more traditional methods.
With a planned layoff of hundreds, an old name in Chicago business gets set to fold
The former United Stationers, now part of Staples, is expected to shut down this fall.
Apple Warns Users in 110 Countries They May Be Targets of Mercenary Spyware
Apple alerts suspected mercenary spyware targets in 110 countries, expanding threat notifications that have reached users in over 150 countries.
Skanska small business outreach lead sees opportunity in DBE changes
After hitting hiring goals on a Los Angeles International Airport project, DBE compliance officer Teresa Maxwell outlined how the firm connects with contractors local to its projects.
Trump Team’s Use of Arcane Budget Rule Threatens Medicaid Coverage
Coverage for hundreds of thousands of Arkansas Medicaid enrollees next year is in question after the Trump administration refused to renew a key state waiver. The state might not be the last to have to adjust to an arcane rule change under the One Big Beautiful Bill Act.
Executives who left OpenAI in 2026
OpenAI continues to experience significant executive turnover in 2026, with key figures like Brad Lightcap and Fidji Simo stepping down.
What's Coming in September: New iPhones, Apple Watches and More
Apple will introduce at least five new devices at its iPhone-centric event next month, and it's also possible we'll get devices waiting on Siri AI like the Apple TV. iPhone 18 Pro The iPhone 18 Pro is going to look like the iPhone 17 Pro, but with a smaller Dynamic Island. It's getting some internal updates, including a new Wide camera with a variable aperture for more control over lighting and a faster A20 Pro chip built on a new 2nm process.
City of Augusta highlights resources for small businesses, entrepreneurs
Augusta city officials are reminding local entrepreneurs and small business owners of resources available to help start, grow, and strengthen their businesses.
DJI Mic Mini 2S review: The best tiny mic now offers a pro experience
DJI’s Mic Mini 2S offers high-quality audio and ease of use, and it’s now better for pros due to the new internal 32-bit float recording.
Gorge Amphitheatre founders plan new music venues
The project, dubbed The Hilltop, will feature a 1,000 to 1,200-seat indoor theater and a 2,000-seat outdoor venue on a property adjacent to the Gorge Amphitheatre.
Embracer tops quarterly profit expectations as PC, console business improves
Swedish gaming company Embracer posted first-quarter adjusted operating profit that more than doubled analysts' expectations on Thursday, driven by stronger earnings from its PC and console games business.
Car crashes into Trap House Chicken on Normandy Blvd.; owner says business will stay open
A car crashed into Trap House Chicken on Normandy Blvd. Wednesday afternoon, sending the popular restaurant into cleanup and recovery mode — but its owner says the doors will stay open.
Twitch is Mining Peoples' Streams to Train Amazon's AI
Here's how to opt out of Twitch's new generative AI training setting.
Sports fans never sleep: Ericsson says 5G is becoming central to game-day
Fans increasingly expect seamless digital experiences before, during and after sporting events, p | The World Cup may be over, but the race to improve fan experiences is not. Advanced 5G networks are increasingly shaping everything from stadium connectivity and concessions to media production and public safety.
Kelly Ripa reveals graphic details of gum surgery amid ‘Live’ absence: ‘Caused gum recession’
Kelly Ripa revealed graphic details of her painful gum surgery amid her ‘Live With Kelly and Mark’ absence. She also explained her ‘good bad habit’ that led to health issue and ‘gum recession.’
Galaxy Entertainment Group Q2 & Interim Results 2026
Leading Macau’s Non-Gaming Diversification Through MICE, Entertainment and Sporting Events Gaming and Entertainment Division on a Normalized Basis,Q2 2026 Net Revenue Grew 6%, Adjusted Property EBITDA Grew 9% and Adjusted Property EBITDA Margin Expanded From 30.5% to 31.4% YoY Announced Interim Dividend of $0.90 per Share Continued to Ramp up Capella at Galaxy Macau HONG KONG, Aug. 12, 2026 (GLOBE NEWSWIRE) -- Galaxy Entertainment Group (“GEG”, “Company” or the “Group”) (HKEx stock code: 27) tod
Council Bluffs coaches monitor heat during fall sports practices
With temperatures feeling near 100 degrees, fall sports practices are underway across the area, and coaches are adjusting schedules and protocols to keep players safe.
Linebacker Kip Lewis on transfer Cole Sullivan’s adjustment
Linebacker Kip Lewis praises transfer LB Cole Sullivan for how quickly he has adapted to the Sooners' defense.
Monumental, Capital One renew arena naming-rights deal for two more decades
Monumental Sports and Entertainment and Capital One Arena have extended their arena naming rights deal for two more decades.
Joby Aviation to Scale Defense Business Through Acquisition of Resonant Sciences
Acquisition will significantly expand Joby’s defense business by adding a fast-growing company with established programs, classified capabilities and scaled manufacturing operations` Upon closing, Resonant will become Joby’s dedicated defense business, continuing its existing programs while expanding its portfolio to include Joby’s hybrid aircraft and autonomy technologies. Joby’s commercial aircraft business will remain focused on its electric air taxi initiatives Combination will create immediate opportunities to unite Joby’s dual-use aircraft, propulsion and autonomy technologies with Resonant’s radio frequency (RF), sensing and mission systems capabilities as well as its world-leading expertise in low-observability aircraft design Resonant delivered more than $100 million in trailing-twelve-month revenue, representing approximately 40% year-over-year growth, alongside strong adjusted EBITDA generation, driven primarily by long-cycle programs with the U.S. government, prime contractors and next generation defense technology programs
Australian Athletes Who've Made Their Mark Across Bay Area Sports
As the 49ers prepare to open the 2026 season in Australia, here's a look at some of the Australian athletes who have left their mark on Bay Area sports.
Everything New in iOS 27 Beta 5
We're a little over a month away from the launch of iOS 27, and Apple is continuing to make changes. The fifth beta of iOS 27 changes the look of some app icons and adjusts Liquid Glass, plus it adds some smaller features that make the iPhone just a little nicer to use. App Icons There are updated Liquid Glass icons for Safari, Siri, Settings, Remote, App Store, and Preview. Some of the icons have been entirely redesigned, while others feature more detail than before.
Wall Street Bets: DraftKings, Penn Entertainment, Inspired Entertainment, New York online sports betting
J.P. Morgan’s Dan Politzer examined the recent DraftKings’ earnings call on August 7: “DraftKings’ report itself was better than feared, as 2Q Adjusted EBITDA o
AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice
AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.