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Highmark Health Plans appoints new president
Highmark Health Plans — the Pittsburgh based nonprofit that insures nearly 8 million people — has a new president. Gustavo “Gus” Giraldo will begin effective immediately, parent company Highmark Health announced Monday. Giraldo comes most recently from CVS Health-owned Aetna, where he served as senior vice president of individual and
Postal Service issues new mail-in ballot rule
The U.S. Postal Service said the new rule won't take effect unless the injunctions in various lawsuits are resolved
‘We got attacked’: Canada says it will retaliate for new tariffs enacted by Trump
President Trump tried in recent days to use an untested legal power to force Canada to swallow trade concessions. Instead, Canadian Prime Minister Mark Carney quit the negotiations. 50 percent U.S. tariffs took effect early Saturday on an array of Canadian products. Carney said Canada will retaliate on Sept. 8 for the new tariffs with its own trade measures. President Trump on Monday said he would impose higher tariffs on additional Canadian products beginning Jan. 1.
Riser House Entertainment Adds Anna Widmer As VP Of Promotion
Riser House Entertainment has added Anna Widmer as VP of Promotion, effective at the beginning [...]
A New Study Explores Whether Exercise Can Really Cancel Out the Health Risks of Your Desk Job
Scientists debate whether it’s possible to fully reverse the metabolic effects of a sedentary life.
Common medications may change your gut for years
Common medications may reshape the gut microbiome long after the last dose is taken. In a study of more than 2,500 people, researchers found lasting microbial changes linked not only to antibiotics, but also to antidepressants, beta-blockers, acid-reducing drugs, and benzodiazepines. Some effects were still detectable years later, suggesting past medication use may strongly influence the gut bacteria people carry today.
Mozambique strengthens regulation of medicines and imported vaccines, boosting health protection
Mozambique has reached a major milestone in strengthening the regulation of medicines and imported vaccines, with its national regulatory authority recognized by the World Health Organization (WHO) as having a stable, well-functioning and integrated regulatory system.The Autoridade Nacional Reguladora de Medicamentos de Moçambique (ANARME) has achieved Maturity Level 3 (ML3) for the regulation of medicines and imported vaccines under WHO’s global classification of national regulatory authorities.Mozambique becomes the 10th country in Africa to reach ML3, joining Egypt, Ethiopia, Ghana, Nigeria, Rwanda, Senegal, South Africa, Tanzania and Zimbabwe and marking further momentum in strengthening regulatory systems across the region.For people in Mozambique, stronger regulation means greater assurance that medicines and vaccines are appropriately evaluated for quality, safety and efficacy and monitored throughout their lifecycle. It also strengthens the country’s ability to identify and respond to safety concerns and substandard or falsified products, while supporting timely access to quality-assured health products.“Mozambique’s achievement is the result of sustained investment in regulatory capacity that will deliver crucial benefits for public health,” said Dr Sylvie Briand, WHO Chief Scientist and Assistant Director-General a.i. for Health Systems, Access and Data. “Strong regulatory systems protect people, build confidence in health products and help countries respond more effectively to evolving public health needs and challenges. Mozambique’s progress also contributes to advancing regulatory capacity across Africa and promoting more equitable access to safe and quality-assured medicines and vaccines.”Building a stronger regulatory systemMozambique’s achievement follows years of sustained efforts to build the institutions and capabilities needed for effective regulation.WHO worked closely with ANARME throughout this process, assessing the national regulatory system and supporting the authority in addressing identified gaps and strengthening priority areas.WHO evaluates national regulatory systems using its Global Benchmarking Tool (GBT), which assesses the regulatory functions required to ensure the quality, safety and efficacy of medical products. These include registration and marketing authorization, licensing, market surveillance and control, pharmacovigilance, regulatory inspection, laboratory testing and oversight of clinical trials, as applicable. WHO’s maturity levels range from 1 to 4. Reaching ML3 confirms a stable, well-functioning and integrated regulatory system, while ML4 represents an advanced system focused on continuous improvement.Benefits for Mozambique and the African continentAn ML3 regulatory system can support more timely and predictable regulatory decisions, reinforce safety monitoring and help ensure that health products entering and remaining on the market meet appropriate standards.It also creates greater opportunities for regulatory cooperation and reliance – approaches that help authorities make use of the work and decisions of trusted regulators, reduce unnecessary duplication and allocate limited resources more efficiently, while maintaining rigorous standards for quality, safety and efficacy.As the first Portuguese-speaking country in Africa to reach ML3, Mozambique’s experience can also contribute to strengthening regulatory systems and fostering greater cooperation, knowledge sharing and reliance among Portuguese-speaking countries and across the African continent. Its achievement further reinforces a more connected African regulatory ecosystem, providing a solid foundation on which the newly established African Medicines Agency can build to advance regulatory convergence and cooperation across the region.Strengthening confidence in regulatory recognitionMozambique’s achievement comes as WHO strengthens the process through which the performance of national regulatory systems is recognized.The newly established Technical Advisory Group on Regulatory Systems Strengthening (TAG-RSS) brings together independent international experts to advise WHO on whether recommendations concerning regulatory authorities reaching ML3 and ML4 and WHO-Listed Authorities, are supported by the findings of WHO evaluation processes. Its recommendations provide an additional level of independent assurance, strengthening the impartiality, transparency and credibility of WHO’s recognition process.Mozambique is among the first countries to achieve ML3 following consideration and recommendation by the TAG-RSS. As part of the same TAG-RSS process, South Africa was recommended to retain its ML3 status for the regulation of vaccines manufactured, imported or distributed in the country, following an additional WHO assessment. This extends the recognition first granted in 2022 and underscores the sustained performance of the South African Health Products Regulatory Authority (SAHPRA).The two recognitions highlight continued progress in strengthening regulatory systems across Africa, as well as the importance of continued performance, improvement and assessment in sustaining regulatory maturity.WHO will continue working with ANARME and SAHPRA to sustain these gains and support continuous improvement as science, technologies and public health needs evolve.
A hidden “on switch” in human DNA has finally been decoded
Researchers have used AI to uncover the DNA signature of a key genetic “switch” involved in turning genes on. After analyzing about 500,000 DNA sequences, the model identified the initiator in roughly 60% of human genes. The breakthrough could help predict the effects of harmful mutations and eventually contribute to decoding the broader genetic instructions that control gene activity throughout the body.
Scientists turn tiny “defects” into a 5.5x heat transfer boost
Scientists have developed an ultrathin coating that could dramatically improve how efficiently heat is transferred during condensation. By turning tiny polymer structures once considered “defects” into places where water droplets can form, then helping those droplets detach quickly, the new surface keeps exposing fresh areas for condensation. In tests on copper tubes, it transferred heat up to 5.5 times more effectively than conventional copper and more than 50% better than a standard water-repelling coating.
The science behind social media bans, and why they don’t work
Explore the ineffectiveness of social media bans for teenagers and discover solutions that promote healthy digital habits instead.
Cannabis use linked to 37% higher stroke risk in massive study
A massive analysis involving more than 100 million people has found strong links between recreational drug use and stroke, including among younger adults. Cocaine was associated with nearly double the risk of stroke, amphetamines with more than double the risk, and cannabis with a 37% increase.
Canada to impose retaliatory tariffs across a raft of US sectors, Carney says
The tariffs will take effect Sept. 8, Canada's prime minister said.
This frozen fiber makes light and sound interact 1,000x more strongly
Freezing the liquid core of an optical fiber produced an extreme environment where light and sound interact more than 1,000 times more strongly than in ordinary fibers. Researchers used the effect to create optoacoustic memory, potentially paving the way for lower-energy photonic computers and advanced quantum technologies.
Multilingual people may have brains up to 13 years younger
People who speak several languages may have brains that age more slowly, with four-language speakers showing brains that appeared about 13 years younger than those of monolinguals. Starting earlier and becoming highly fluent were also linked to a stronger effect.
Arsenal 3-0 Coventry
Rachel: The most confident football I have seen from this Arsenal team for many years. Vince: Odegaard and Havertz look like new signings, exuding energy and grit that were missing when they were nursing injuries. Tzolis was absolutely brilliant, he gives Arsenal an outlet on the left which we haven't really had to that much effect over the last few seasons with his direct nature which is an absolute joy to watch.
PlayStation Blackout Starts Tomorrow, But Are You Taking Part?
The #PSBlackout social action kicks off tomorrow, but who is taking part, and will it have the effect participants desire? Probably not.
No deal reached in U.S.-Canada trade talks as 50 percent tariffs take effect
The U.S. will impose new tariffs on Canada after the two countries failed to reach a deal.
Blue Cross changes spark protest over mental health care access
Therapists, patients and advocates protested outside Blue Cross Blue Shield of Michigan headquarters over changes set to take effect March 1.
A Mother’s Age Can Affect Her Offspring in Ways Scientists Are Only Starting to Understand
The effects of maternal age may travel through generations without being written into DNA.
Hidden magnetism inside atoms may explain mysterious gamma rays
For decades, scientists have puzzled over why certain atomic nuclei unexpectedly produce large numbers of low-energy gamma rays. A new experiment traced the effect to magnetic changes inside the nucleus, where protons and neutrons effectively flip their tiny internal magnets. The discovery could sharpen models of everything from nuclear reactions on Earth to the creation of heavy elements in stars and neutron star mergers.
Josh Franco Receives the 2026 APSA Award for Teaching Innovation -
The APSA Award for Teaching Innovation honors a wide range of new directions in teaching by recognizing a political scientist who has developed an effective new approach to teaching in the discipline. Citation from the Award Committee: [...]
NASA Data Feeds River Forecasts as Snow Drought Effects Linger
NASA Earth science data is supporting machine-learning forecasts that inform decisions about water, power, and public safety in Washington state.
Dr. Stacy Sims Joins Livelong Media as Chief Science Advisor
Livelong Media today announced that Dr. Stacy Sims MSc, PhD has joined the company as Chief Science Advisor, effective July 31, 2026. Sims, an exercise physiologist and nutrition scientist known for her research on female physiology, will help guide the scientific direction of Livelong's content and live event series in an ongoing advisory capacity.
High touch, not merely high tech
Commentary: AI is revolutionizing the customer journey in a wide array of dimensions. What must not be lost in this revolution, though, is the human element — including empathy, care, ethical reasoning, as well as effective decision-making and support.
The Apophis encounter in 2029: A rare opportunity for planetary science and defense
The near-Earth asteroid Apophis will make an extremely close flyby of Earth on April 13, 2029, at a distance of approximately 38,000 km—an event that occurs on average only once every 7,500 years, offering an unprecedented opportunity for planetary science and planetary defense. However, significant uncertainties remain regarding the physical parameters of Apophis, such as its shape, spin state, internal structure, and material composition, and predictions of tidal effects—including potential orbital changes, spin acceleration, surface material displacement, and dust ejection during the flyby—are highly dependent on model assumptions. Although multiple nations have planned exploration missions, how to coordinate global observational resources within the limited time window, optimize rapid-response mission architectures, and translate scientific understanding into effective planetary defense strategies remain critical challenges to be addressed.
Paris Jackson opens up about ‘painful’ electroconvulsive therapy. She’s not alone
Women are still being treated with electroconvulsive therapy, including Paris Jackson. A new study shows that women face the most side effects.
What Is The Black Drop Effect? How An Optical Phenomenon Frustrated Astronomers And May Have Changed Australia’s History
We don’t get to see it very often, but that makes it even more important when it happens.
Climate change is cooking Europe’s oceans, scientists find
Global warming is the main driver of this year’s marine heat waves, with knock-on effects for ecosystems and extreme weather.
"I don't know if they will keep funding that one" - Former EA manager doesn't believe the next Mass Effect will survive Saudi takeover
No one knows whether or not we're going to see a new Mass Effect from BioWare, but the chances of that happening look vanishingly small each passing day.
A look at where mosquito health alerts are in effect across Florida
Health alerts are in effect for several counties in Florida as officials monitor mosquito-borne illnesses after heavy rainfall.
CT providers work to curb HUSKY losses from ‘Big Beautiful’ bill
Federal changes to Medicaid eligibility take effect in January, and 110K CT residents could lose HUSKY. Hospitals and clinics are preparing.
How much of a cancer drug is too much? Patients, researchers challenge FDA-approved dosages
Patients and researchers point to evidence that many cancer drug dosages are excessive, and that reducing the amount and frequency could save billions of dollars and prevent some of the worst side effects.
Fluctuating work hours increase health risks for workers
Workers who juggle volatile work hours that change from week to week may experience adverse health effects that impact their ability to work, although the limitations vary by gender, say researchers at the University of Illinois Urbana-Champaign who conducted a recent study.
Vikings’ Beloved Rookie Gets Bluntly Honest About His Role
The Minnesota Vikings drafted fullback Max Bredeson out of Michigan in the fifth round of the 2026 NFL Draft.Bredeson slots in right away as the replacement for C.J. Ham at FB and is already taking to the Vikings’ offense very well. He was a vocal leader at Michigan and projects to have the same effect […] The post Vikings’ Beloved Rookie Gets Bluntly Honest About His Role appeared first on HEAVY.
Cost-effectiveness analysis of early antihypertensive treatment for hypertension detected at health screening
Hypertension Research - Cost-effectiveness analysis of early antihypertensive treatment for hypertension detected at health screening
Trump proposal would end ‘roadless rule’
DECK: The administration’s move would end ‘roadless rule,’ affect nearly 45 million acres, though not in Colorado The Trump administration has proposed ending decades-old rule that bars road building and logging millions of acres of national forest land, arguing it has hindered the country’s wildfire fighting efforts. The proposal, if put into effect, would affect […]
Boyle Heights community clinic says hundreds of residents treated for "toxic exposure" after Lineage fire
Some of the most common diagnoses among Boyle Heights patients included the toxic effects of smoke, contact/exposure to hazardous substances and acute upper respiratory infection.
Bill Rasmussen, ESPN founder who conceived a cable network devoted to sports, dead at 93
Chris Berman calls Bill Rasmussen "our George Washington" after the visionary ESPN founder passed away at 93 from the effects of Parkinson's disease.
Volatile weekly work hours have adverse effects on health, employment
Unstable work hours negatively affect employees’ health, but they affect men and women differently
ESPN founder Bill Rasmussen dies at 93
He died Tuesday from the effects of Parkinson's disease, ESPN announced.
Xbox Game Pass confirms second wave of new games for August
Resonance: A Plague Tale Legacy, Blood Dungeon, and BlazBlue Entropy Effect X are part of the second wave of games coming to Xbox Game Pass in August 2026.
Xbox announces 9 new games coming to Game Pass this month
Microsoft has revealed the next lineup of games that will be joining the Xbox Game Pass library this month. The list includes Vapor World: Over the Mind, BlazBlue Entropy Effect X, Relooted, and more.
Waist Size Is Accurate Way To Gauge Unhealthy Excess Weight, Study Says
By Dennis Thompson HealthDay ReporterTUESDAY, Aug. 18, 2026 (HealthDay News) — Are you worried that extra pounds might be harming your health? Check the notches on your belt, a new study suggests. Waist size might be one of the simplest and most effective measures to detect health risks associated ...
Scientists cited by Heritage Foundation report on women’s sports say it misrepresented their research
The conservative think tank’s report claims that high-intensity and elite sports training has lasting effects on menstrual cycles and fertility
Scientists may have finally proved that “empty” space isn’t really empty
A magnetar’s colossal magnetic field may have revealed a quantum effect predicted by Werner Heisenberg nearly 90 years ago, in which seemingly empty space alters the behavior of light. If confirmed, the discovery could offer the first direct evidence of vacuum birefringence and open a new window into the strange physics of the quantum vacuum.
Opinion | Yes, Higher Ed Shapes Students’ Politics. Here’s How.
Different disciplines have different ideological effects.
Can 5 minutes of movement have health benefits? A new study says yes
Five-minute walks every hour appear to be a realistic and effective way to mitigate the effects of prolonged sitting, writes columnist Carrie Dennett.
Balm in Gilead hosts free health forum at local church to educate folks about lung cancer
The goal was to educate the community on the symptoms and side effects of lung cancer, and to keep them in tune with their bodies.
Trump has to balance American politics with American interests, political analyst says
'Fox News Sunday' panelists debate the geopolitical and economic fallout from the Iran war, its effect on U.S. gas prices and what it means for President Donald Trump ahead of the 2026 midterm elections.
California could soon limit social media for kids
California lawmakers are moving forward with proposed laws that address the harmful effects of social media on children, including restrictions on addictive features and the ability for parents and children to sue platforms for damages.
Everything you wanted to know about political signs but were afraid to ask
With the Sept. 8 primary approaching, learn NH laws for campaign signs, including placement rules, removal deadlines, and their effectiveness.
Tiny graphene wrinkles create surprisingly powerful electrical effects
Scientists have discovered that tiny, sharply curved wrinkles in graphene can dramatically alter its electrical behavior, creating surprisingly strong charge separation. The finding suggests future electronics could be tuned by reshaping materials at the atomic scale instead of changing what they’re made of.
The post-Hormuz era offers Africa a great opportunity
But to capture its benefits, the continent needs to develop an effective, common maritime policy.
The trouble with getting used to miracles
Success has a strange effect on wonder. It turns miracles into infrastructure!
Dritwood Outdoors: Wildlife science demands effective communication
Wildlife management has come a long way from the days of Aldo Leopold traversing the New Mexico mountains on horseback and the Wisconsin River Valley by canoe. Back then, most decisions were based primarily on observation and experience. Today, highly trained wildlife biologists use sophisticated research, technology and mountains of data to understand everything from population dynamics and habitat needs to disease transmission and predator-prey relationships.
Bernalillo County's Behavioral Health Unit rapidly grows, diverting 911 calls
Officials say the three-unit teams have become more effective since paramedics were authorized to administer the antipsychotic drug olanzapine.
People in Business: FOCUS names; Nitrous Effect appoints; EDC names; West Community promotes
Catch up on local business appointments, hires and promotiions.
Wildlife science demands effective communication
Wildlife management has come a long way from the days of Aldo Leopold traversing the New Mexico mountains on horseback and the Wisconsin River Valley by canoe. Back then, most decisions were based primarily on observation and experience. Today, highly trained wildlife biologists use sophisticated research, technology and mountains of data to understand everything from population dynamics and habitat needs to disease transmission and predator-prey relationships.
Are You Really ‘Maxxing’ Your Health? What to Know About 4 Viral Health Hacks
“Maxxing” trends are growing in popularity on social media, but experts say these health hacks, which promote optimizing nutrition, sleep, and fertility, may be ineffective or even pose health risks.
Researchers Find That Waist Size Is a Powerful Indicator of Health Risks
Measuring waist size may be one of the simplest and most effective ways to detect obesity-related health risks, according to a study by Rutgers Health researchers. The study, published in JAMA Network Open, found that combining body mass index (BMI) with waist circumference, or using waist circumference alone, performed as well as a newly proposed obesity definition that incorporates multiple body measurements.
ENTERTAINMENT: ‘Ghost Army’ film documents World War II trickery
The MacArthur Museum screens “The Ghost Army,” a documentary about American soldiers, “many of whom would later have illustrious careers in art, design and fashion,” who tricked the Germans with rubber tanks, sound effects and carefully crafted illusions during World War II, 6:30 p.m. Tuesday.
Radiation vest tested on NASA moonshot can quell effects of solar storms, study suggests
A new study suggests a protective vest tested on a manikin during NASA's first Artemis moonshot could slash the radiation exposure of lunar astronauts during severe solar storms.
Scientists who narrowly missed out on an NIH grant were 6.1% more likely to produce a top-5%-cited paper over the following decade than equally promising scientists who just got funded — a Kellogg-led study suggesting that an early setback can have surprisingly long-lasting effects.
A natural experiment around an NIH funding cutoff found higher-impact work among near-miss scientists who stayed active, alongside substantial attrition from the system.
Chinese sensor feat may help smart watch detect submarine 500 metres deep
Compact chip containing Hall-effect sensor can pick up faint magnetic fields by generating a tiny voltage without increasing noise output.
Wildlife science demands effective communication
Wildlife management has come a long way from the days of Aldo Leopold traversing the New Mexico mountains on horseback and the Wisconsin River Valley by canoe. Back then, most decisions were based primarily on observation and experience. Today, highly trained wildlife biologists use sophisticated research, technology and mountains of data to understand everything from population dynamics and habitat needs to disease transmission and predator-prey relationships.
Brandon Butler column: Wildlife science demands effective communication
Wildlife management has come a long way from the days of Aldo Leopold traversing the New Mexico mountains on horseback and the Wisconsin River Valley by canoe. Back then, most decisions were based primarily on observation and experience. Today, highly trained wildlife biologists use sophisticated research, technology and mountains of data to understand everything from population dynamics and habitat needs to disease transmission and predator-prey relationships.
Scientists solve the mystery of a brain “switch” that can trigger weight loss in opposite ways
Scientists have uncovered why two seemingly opposite ways of targeting the same brain receptor can both promote weight loss. In mice, activating the GIP receptor in the brainstem reduced appetite, while blocking it in the hypothalamus removed a kind of “brake” on fullness signals. The discovery helps explain why very different obesity drugs can achieve similar results and suggests that carefully combining GIP-targeting treatments with GLP-1 drugs like those related to Wegovy and Ozempic could produce stronger effects.
Scientists Are Building a 'Noah’s Ark' of California’s Tide Pools
It will help better track the effects of climate change on the ecosystem.
Cardiac CT links air pollution to increased risk of coronary disease
Cardiac CT scans may give clinicians a way to visualize the effects of environmental exposure before cardiovascular events even occur.
This bizarre star is defying physics—scientists stunned by unexplained quantum effect - Futura-Sciences
Published in Nature, the study details observations of 1E 1547.0-5408, a magnetar formed by a massive star’s supernova explosion. The star rotates once every 2.1 seconds and generates a magnetic field more than one trillion times stronger than Earth’s. Unprecedented multi-observatory campaign Testing vacuum birefringence requires magnetic fields 100 million...
Dallas Heat and Mental Health Effects
Dallas summers will wreck you. Pro tip: stay out of that air-conditioned bar.
Montenegro Wants To Be Europe’s Next Crypto Hub, But Weak Regulation Might Be Costing It Big Business
Montenegro’s crypto market is growing despite regulatory gaps that could deter investors and leave billions in digital-asset transactions beyond effective oversight.
Armstrong appoints senior advisor Conner Swanson to lead ND Department of Health and Human Services | North Dakota Office of the Governor
Gov. Kelly Armstrong appointed Conner Swanson to lead the North Dakota Department of Health and Human Services (DHHS), effective Aug. 29, citing his experience with complex policy issues at both the state and federal levels and his guidance to the agency through the Governor’s Office these past two years.
Virginia hemp businesses file lawsuit over new restrictions taking effect Saturday
A major change is about to reshape Virginia’s hemp industry, with new restrictions set to take effect Saturday as several businesses try to stop the law.
Suno is trying to look more like a real music production tool
The latest version of Suno Studio adds MIDI, a chatbot, and custom AI effects.
AI needs science’s search history
“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.
The drug lenacapavir is a mighty weapon against HIV. Its rollout gets mixed reviews
It's a twice-a-year injection that is remarkably effective in preventing an HIV infection. Distribution is starting. But questions are being raised about getting it to the areas that need it most.
City Council set to vote on year-round outdoor dining
If approved, the changes would take effect immediately.
Dr. Scott Terrell Named Vice President, Animals, Science and Environment for Disney Experiences
Disney Experiences has appointed Dr. Scott Terrell as vice president of animals, science and environment in Lake Buena Vista, Fla., effective 3 August.
Is the World Bank Ready for a Bigger Role in Global Health Financing?
The global health architecture is facing a financing crisis. Various proposals have been put forward, including an IDA Health Window—a ring-fenced fund at the World Bank for countries to seek support for financing their health systems. But could the World Bank absorb and effectively channel a greater share of health financing in the future? As the largest and most influential multilateral development bank, it is an attractive option: it works directly with country governments, provides financing through national budgets, offers both loans and grants, and supports investments across sectors based on country demand.
Asia-Pacific parliamentarians urge bolder action for universal health coverage, climate resilience and responsible AI
Parliamentarians representing 16 countries from across the Asia-Pacific region concluded the Ninth Meeting of the Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) today, reaffirming their key role in advancing universal health coverage (UHC) amid the risks and opportunities posed by AI and climate change. In adopting the Phnom Penh Communiqué, parliamentarians urged fellow legislators regionwide to strengthen sustainable financing for UHC to widen access to health for all, including the most vulnerable populations; promote responsible governance of AI amid ethical concerns over this fast-evolving technology; and build climate-resilient health systems to anticipate and respond to mounting pressures ranging from rising sea levels in coastal areas to air pollution and other environmental degradation.The National Assembly of Cambodia, with support from Cambodia’s Ministry of Health and the World Health Organization (WHO), hosted the Forum in Phnom Penh from 11 to 13 August 2026 – the first time the Forum has convened in a Mekong country.Parliamentarians urge action to close gaps in accessIn the Communiqué, parliamentarians recognized that at-risk and marginalized groups are the ones most severely affected by gaps in access to health services. These groups include people living in poverty, women and children, persons with disabilities, older people, migrants, refugees, and those in rural, remote or island communities. The Communiqué urges fellow parliamentarians and policy-makers to advocate for laws and policies that support sustainable financing to protect people from financial hardship, with a focus on primary health care, prevention and equity. "The Communiqué is a call to action. It sets out ambitious, concrete measures that deliver meaningful impact on the ground. We are all accountable for advancing universal health coverage and translating our commitments into tangible results. Cambodia is fully committed to advancing UHC, including the promotion of ‘healthy people, prosperous country’ campaign,” said Samdech Maha Rathsapheathika Thipadei Khuon Sudary, President of the National Assembly of the Kingdom of Cambodia.His Excellency Professor Chheang Ra, Minister of Health of the Kingdom of Cambodia, highlighted the need for collaboration beyond the health sector. “Universal health coverage cannot be achieved by the Ministry of Health alone. It requires support, particularly from parliamentarians, across political, legislative, financial, social protection, education, infrastructure, and environmental domains. While each country follows its own path, one factor is universally critical for success: strong governance and leadership. We all believe in this principle, and in our respective political roles, we remain committed to strengthening these key success factors to ensure that no one is left behind.”Promoting responsible AI adoption Parliamentarians acknowledged that, while AI has already demonstrated its ability to improve access to health services and support delivery, careful and ethical governance is necessary to safeguard quality, safety, privacy and public trust. This underscores the importance of parliamentarians in promoting legal and regulatory frameworks addressing liability, records ownership and data governance, while embracing innovation that protects ethical practice.“Without strong governance, safeguards for privacy and data security, sustainable financing, and attention to those most at risk of exclusion, new technologies may widen existing gaps instead of closing them. This is why parliamentarians matter. We pass laws. We approve budgets. We scrutinize government action. We represent communities. We can ask whether health services are reaching rural, remote, ageing, poor, and marginalized populations. We can ask whether innovation is being guided by equity, evidence, and ethics,” said Hon. Man Hee Lee, President of the Asia-Pacific Parliamentarian Forum on Global Health.Building climate-resilient health systemsParliamentarians also reiterated that the climate crisis is a direct threat to people’s health and to achieving UHC more broadly, deepening the same gaps in access already faced by at-risk and marginalized communities. They recognized the need for WHO Member States to ensure sufficient national appropriations and oversight, and for parliamentarians to raise awareness in their constituencies and mobilize local action in building climate-resilient and sustainable health systems.“Universal health coverage, climate change and AI cannot be addressed in isolation. The same communities struggling to access health services today are often the ones most exposed to climate shocks, and most in need of the opportunities AI can offer if this technology is governed responsibly,” said Dr Saia Ma’u Piukala, WHO Regional Director for the Western Pacific. “Having served previously in this Forum myself as a parliamentarian from Tonga, I recognize how the Phnom Penh Communiqué reflects the shared resolve of legislators across the Asia-Pacific region: the laws parliamentarians pass and the budgets they approve help ensure this progress reaches the people who need it most.”As the Forum drew to a close, delegates reflected on what they would carry back to their own parliaments and constituencies.“I wish to share three points here worth carrying home from Phnom Penh: we need to invest in primary health care as the foundation of coverage; we need to remove the barriers that keep people from care, whether financial, geographic or social; and we need to build systems that are inclusive by design, protecting those most at risk of being left behind,” added Hon. Ouch Borith, First Vice-President of the Senate of the Kingdom of Cambodia.###Notes for editors:The Asia-Pacific Parliamentarian Forum on Global Health (APPFGH) is a platform for parliamentarians to exchange ideas, build political will, strengthen capacity and foster collaboration towards sustainable health action. This was the ninth meeting of the APPFGH, with the theme “Universal Health Coverage in the era of Climate Change and Artificial Intelligence”. Target 3.8 of the Sustainable Development Goals calls on countries to achieve universal health coverage, including financial risk protection, access to quality essential health services, and access to safe, effective, quality and affordable essential medicines and vaccines for all. In the Western Pacific, UHC service coverage index (SDG 3.8.1) rose from 63 in 2000 to 81 in 2023 (figures include Indonesia), and roughly one in four people in the Western Pacific have experienced financial hardship (SDG 3.8.2). Progress towards UHC in the Asia-Pacific region remains uneven, with hundreds of millions of people still lacking access to essential health services or facing financial hardship due to health-related expenses. Strengthening the role of parliaments – through legislation, financing and oversight – is central to closing this gap and accelerating progress towards UHC across the region.Parliamentarians participating in APPFGH in Cambodia this week include: Hon. Pehin Dato Adanan YUSOF, Brunei Darussalam; Hon. Rosmawatty ABDUL MUMIN, Brunei Darussalam; Hon. LORK Kheng, Kingdom of Cambodia; Hon. YOS Phanita, Kingdom of Cambodia; Hon. KHOUN Khundy, Kingdom of Cambodia; Hon. HENG Halim, Kingdom of Cambodia; Hon. KHOENG Noupheap, Kingdom of Cambodia; Hon. SENG Nhak, Kingdom of Cambodia; Hon. LY Sukry, Kingdom of Cambodia; Hon. NHOEURN Raden, Kingdom of Cambodia; Hon. Dr Ratu Atonio LALABALAVU, Republic of Fiji; Hon. Vijay NATH, Republic of Fiji; Hon. Man Hee LEE, Republic of Korea; Hon. Dr Jiho CHA, Republic of Korea; Hon. Jonghun BAEK, Republic of Korea; Hon. Youngsuk SEO, Republic of Korea; Hon. Dr Phayvanh KEOPASEUTH, Lao People’s Democratic Republic; Hon. Suhaizan Bin KAIAT, Malaysia; Hon. Dr Perpetua KONMAN, Federated States of Micronesia; Hon. Ganmaa DAVAASAMBUU, Mongolia; Hon. Charmaine SCOTTY, Republic of Naoero; Hon. Vincent Ambance KUMURA, Papua New Guinea; Hon. Dr Edwin CRUZADO, Republic of the Philippines; Hon. AUUAPAAU Mulipola Aloitafua Mulipola, Samoa; Hon. ASIATA TAVUI Tafu Salevao, Samoa; Hon. Dr Alani Petelo TANGITAU, Tonga; Hon. Paul PAOLO, Republic of Vanuatu; Hon. Franklyn Ezra WILLIAM, Republic of Vanuatu.For more information, contact: WHO Regional Office for the Western Pacific: wprocom@who.int National Assembly of the Kingdom of Cambodia (International Relations Department): ir.nacambodia@gmail.com
Cardinals may be shifting perception
The Cardinals played an enjoyable brand of football, and Carson Beck was a revelation in the Hall of Fame game. The combined effect was a game that shifted national and local perceptions.
Small Business Spotlight: Specialty dental practice takes root on Market St.
WHAT MADE YOU WANT TO OPEN BLUE HERON ROOT CANAL SPECIALISTS? OWNER SARAH ERMOSHKIN: “I’ve always been an entrepreneur at heart. When I was 23 years old, I owned a cafe in Seattle, where I even fought to oppose oppressive sales taxes on espresso drinks. After selling that business, I got married and started a family. Once my children were in school, I attended dental school through the Navy Health Professions Scholarship Program (HPSP), which covered my tuition and provided a stipend. From the beginning, my goal was to eventually own my own practice after completing my military service. The work I do is incredibly rewarding and being able to create an environment that puts patients first while helping employees grow professionally makes every day as a business owner meaningful.” WHAT DOES YOUR BUSINESS PROVIDE? ERMOSHKIN: “Endodontists are often called ‘pain doctors’ because our primary mission is to relieve pain and save natural teeth. We specialize in root canal therapy, retreatment of nonhealing root canals, treatment of root resorption, apicoectomies – microsurgical root-end procedures – and vital pulp therapy for children. Our goal is to preserve teeth that might otherwise need to be extracted and replaced with implants. Saving a patient’s natural tooth is almost always the best long-term solution for their oral health.” HOW DOES YOUR MILITARY TRAINING HELP YOUR BUSINESS? ERMOSHKIN: “My military service taught me how to lead, collaborate and make decisions under pressure. I worked closely with senior leadership while treating a large patient population and collaborating with specialists across multiple disciplines. During the COVID-19 pandemic, (I) served a dual role as Navy dentist and as the public affairs officer for Naval Health Clinic Annapolis, where I helped develop medical and dental communications for the midshipmen and support staff, while coordinating with the broader Navy Capital Region. We worked closely with other military treatment facilities to share best practices and deliver consistent public health messaging. Those leadership experiences continue to shape how I lead my team and serve our patients today.” WHAT CHALLENGES ARE YOU FACING RIGHT NOW IN YOUR BUSINESS? ERMOSHKIN: “One of our biggest challenges is overcoming the misinformation surrounding root canal treatment. Root canals are safe, effective and often the best way to relieve pain while preserving a natural tooth. Unfortunately, many people choose extraction because they believe it’s less expensive or because they’ve seen misleading information online. What they may not realize is that losing a tooth can lead to shifting teeth, changes in the way they bite and chew and significantly higher costs to restore their smile later.”
Ozempic may have revealed the brain’s hidden “craving center”
Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and surroundings with rewarding experiences. Packed with GLP-1 receptors, it may act as a crucial control point between thinking about a reward and feeling compelled to pursue it. The discovery could open new approaches to treating addiction as well as obesity.
An Overview of State-Directed Payments and Medicaid Provider Taxes: History and Potential Effects of the Working Families and Tax Cut Legislation on Health Care Costs
Health care provider taxes and state-directed payment policies in the Working Families and Tax Cut legislation are expected to reduce non-Medicaid prices by up to 3.5 percent in markets with provider taxes and reduce spending on Medicaid, commercial and Medicare coverage. Our spending estimates indicate that there will be an additional $29 billion in federal savings on Medicare and commercial coverage for each $100 billion that federal Medicaid spending is reduced.KEY POINTS
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Family businesses often fail to prepare the next generation for their most important role—not as executives, but as owners. As a result, families can gradually lose the ability to direct the enterprise, not because of a single crisis but because ownership capability erodes across generations through predictable governance and succession mistakes. To preserve long-term control, family businesses must deliberately develop owners who can exercise sound judgment, govern effectively, and hold management accountable.
The U.S. Healthcare System is Already Mostly Socialized
Now that Abdul El-Sayed is the Democratic nominee for Michigan’s open Senate seat, the outcome of this crucial race will depend mainly on two things: Whether Republicans succeed in demonizing El-Sayed because he’s brown and a Muslim, and whether they succeed in demonizing him as a left-wing radical. I will defer for the now the question of whether bigotry will be effective this year, although I will address it another day. What I want to address instead is El-Sayed’s signature issue — healthcare. Yes, El-Sayed advocates Medicare for All, a position the usual suspects denounce as “socialism.” I will get to the politics of his stance soon. Today, however, I want to talk about the substance. We should be clear that El-Sayed doesn’t even call himself a socialist. On the contrary, he explicitly disavows the label, saying “I’m a capitalist who just knows about capitalism”. In fact, as I explained in a previous post, the policies that El-Sayed advocates qualify him as a social democrat, not a socialist. Still, El-Sayed advocates a system under which the government would pay almost all medical expenses. Isn’t that socialism? Well, if that is the criterion then much of U.S. healthcare is already socialist. In fact, the government’s role is so large that U.S. healthcare is better described as partially privatized socialism than as anything resembling a free market. Let’s start with the raw numbers on health insurance, which pays the bulk of Americans’ medical expenses. Americans receive health insurance either from private companies or from public programs, overwhelmingly Medicare and Medicaid. Here’s what the breakdown of coverage and spending between private and public looked like in 2024: While a majority of Americans with health insurance get it from private companies, well over 100 million of us are covered by government programs instead. And these government programs pay more total dollars for medical bills than the private insurers do. Why do government programs that cover a minority of the population account for a majority of health insurers’ outlays? Mainly because Medicare covers seniors, and we’re expensive. Also, while Medicaid covers many younger Americans, disabled and elderly beneficiaries account for most of its spending. Even by the raw numbers, then, U.S. health insurance looks as much public as private. But that understates the government’s role: Private health insurance in the U.S. is both highly regulated and heavily subsidized. This is obviously true for the insurance coverage purchased by tens of millions of Americans through the exchanges established by the Affordable Care Act. But employment-based health insurance, which covers 161 million Americans, is far more of a government creation than most people realize. For employment-based insurance exists largely because of huge implicit government subsidies that come with major strings attached. Here’s how that works. If your employer pays you $10,000, that’s taxable income. But if your employer pays $10,000 toward a company health insurance plan that meets certain criteria, it isn’t taxable. That’s a huge effective subsidy, running at more than $300 billion a year. Take that subsidy into account, along with the more than $100 billion per year spent subsidizing policies purchased under the ACA, as well as the outlays on Medicare and Medicaid, and net effect is that the government pays for more than two-thirds of Americans’ health insurance. Granted, there are strings attached. Roughly speaking, employment-based health plans can’t discriminate based on medical history — that is, they can’t deny coverage to employees with pre-existing conditions — and they also can’t offer the plans only to highly compensated employees — a health plan that is only for the C-suite is considered taxable income. So given the restrictions of the federal tax code, employer-based health insurance is a lot like Obamacare, which also prohibits discrimination based on medical history and provides subsidies to make insurance affordable to lower-paid workers. The fact is that virtually all of private healthcare insurance is already well under some form of government control through regulation and tax subsidies. How should we think about this system? First of all, is Medicare socialist? Don’t tell anyone, but the way Medicare operates — it covers every senior’s medical expenses, whatever they turn out to be, while being funded by taxes that depend on one’s income — could be summarized by the old Marxist slogan “From each according to his ability, to each according to his need.” And back in 1961, when Ronald Reagan was the face of a last-ditch effort by the American Medical Association to block the creation of Medicare, he denounced Medicare as “socialized medicine” and warned that it would destroy our freedom. In reality, American freedom survived until Jan. 20, 2025, while Medicare is immensely popular, with an 82 percent favorable rating in the most recent KFF survey. Medicaid, government health insurance for lower-income Americans, comes in at 73 percent. This is in sharp contrast to public views about private insurers, who are widely disliked if not hated and accused of denying essential care. Furthermore, if Medicare is socialism, then the whole U.S. health insurance system, with the government paying most of the bills and placing conditions on private insurers, is almost equally socialist. If you insist on calling any program the government pays for and regulates socialist, then U.S. healthcare would best be described as a partially privatized form of socialism. And one must ask, what is the point of the part that is privatized? Do private insurers add anything positive? Or are they simply parasites, skimming off money that could have been paying for care? The case for viewing insurers as parasites is strong. Many Medicare benefits are now delivered via Medicare Advantage, that is, plans paid for by the government but run through insurance companies. MedPAC, an independent advisory commission, estimates that last year Medicare Advantage plans were overpaid by $84 billion, thanks to practices such as “upcoding,” in which patients’ health problems are overstated to get larger sums from Medicare. Assessing the waste from employer-based insurance is harder, but most evidence suggests that private insurers have substantially higher administrative costs than Medicare does. Furthermore, the complexity of private insurance, with multiple payers all trying to deny care when they can, is a huge burden both on providers — doctors, nurses, and hospitals — and on patients. What do private insurers offer to compensate for these costs? One must go through intellectual contortions to avoid the conclusion that they are, in fact, parasites. Which brings me back to El-Sayed. In supporting Medicare for All, he’s basically calling for an end to the partial, parasitic privatization of a healthcare system that is already hugely dependent on public funding. When one looks at it that way, it’s not at all a radical proposal. Admittedly, the political lift requires overcoming the opposition to higher taxes to pay for Medicare for All. Political realism rather than economics was the reason I and many other progressives supported Obamacare, with all its complexities, rather than demanding an immediate move to Medicare for All. But the political calculus may very well have shifted since the 2000s, as Americans are fed up with a system of unaffordable premiums, rampant claim denials, and byzantine claim administration. Moreover, funding healthcare insurance through taxation would allow for a much more progressive distribution of the cost. That is, compared to the present system, middle-income households would pay less as high-income households would pay more. And the U.S. would stop wasting large sums on pointless administrative costs. So let’s be clear: El-Sayed’s healthcare platform is perfectly reasonable on the merits of cost, fairness and health efficacy. And with private insurers never more hated, while millions of Americans are losing their health insurance, 2026 may be its time. MUSICAL CODA
Biohaven Reports Recent Business Developments and Second Quarter 2026 Financial Results
First extracellular protein degraders in the clinic demonstrate rapid and robust pharmacodynamic effects and compelling safety in nearly 200 individuals dosed,...
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Hemp businesses ask federal judge to block Virginia’s new THC cap
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Science Applications adds David Benson and David Cush to board
Science Applications appointed David Benson and David Cush to its Board of Directors, effective August 20, 2026, expanding the board from ten to twelve members.Original SEC Filing: Science Applications International Corp [ SAIC ] - 8-K - Aug. 10, 2026This is an AI-powered summary. It may contain in…
Hemp businesses ask federal judge to block Virginia’s new THC cap
Seven Virginia hemp businesses are asking a federal judge to block new restrictions on consumable hemp products, arguing the changes will wipe out much of their inventory, trigger layoffs and force some companies to close when they take effect on Aug. 15. The lawsuit, filed July 31 in the U.S. District Court for the Western District of Virginia, challenges a new provision in the state budget that will eliminate an exception for products containing more than 2 milligrams of tetrahydrocannabinol (THC) per package when they also contain at least 25 times as much cannabidiol (CBD).
Same Knee Surgery, Twice the Price: Hospital Monopolies Push Up Healthcare Costs
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