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Islamic Development Bank and Global Fund Strengthen Partnership to Advance Sustainable Health Financing

GENEVA/JEDDAH – The Islamic Development Bank (IsDB) and the Global Fund to Fight AIDS, Tuberculosis and Malaria (the Global Fund) signed on 6 October a new Partnership Agreement to strengthen collaboration and accelerate investments in health across low- and middle-income countries. The agreement, which marks a new chapter in a long-standing relationship, establishes a framework for aligning investments and coordinating financing, mobilizing additional resources, and supporting country-led efforts to build…

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Oct 6 • 8:00 PM EDT • Health • isdb.org
Washington County voters to decide on behavioral health levy renewal

Washington County voters will decide this November whether to renew a 0.5 mill levy that funds behavioral health resources in the community.

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Oct 6 • 7:52 PM EDT • Health • wtap.com
Amarillo Emergency Nursing Symposium draws hundreds of health care professionals
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Oct 6 • 7:46 PM EDT • Health • abc7amarillo.com
ARTober events aim to bring customers into downtown Chico businesses

A month-long lineup of art and community events is underway in downtown Chico, with organizers hoping it will drive foot traffic into local businesses

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Oct 6 • 6:30 PM EDT • Business • krcrtv.com
Florida Department of Health warns of mosquito-borne illnesses in tested Manatee County chickens

DOH- Manatee and the Manatee County Mosquito Control District are coordinating surveillance and prevention efforts by source reduction.

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Oct 6 • 6:07 PM EDT • Health • mysuncoast.com
Elementary Science Curricula Are in Short Supply. Will a Free Resource Help?

Elementary schools face a limited array of science materials, and many don't align with state standards.

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Oct 6 • 5:24 PM EDT • Science • edweek.org
NCAA proposes summer competition for college basketball teams

The NCAA is proposing allowing summer competition between college basketball teams as a potential new revenue source.

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Oct 6 • 5:01 PM EDT • Sports • espn.com
Elizabethton High School Health Academy expands as student interest grows

At 16 years old, Aubri Cline is already doing things she once thought would have to wait until college.

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Oct 6 • 4:27 PM EDT • Health • wcyb.com
Health department requests F-16 crash response grant for exposure testing, staffing

The Grand Traverse County Health Department is requesting approval of a $134,145 grant to cover the response to the F-16 crash.

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Oct 6 • 4:21 PM EDT • Health • upnorthlive.com
Pingree holds double-digit lead as voters back public option for health insurance

Democratic gubernatorial candidate Hannah Pingree holds a double-digit lead over Republican Bobby Charles, while one of her signature health care proposals is even more popular with likely Maine voters, according to a new poll released Tuesday. The survey, conducted by the Maine People’s Resource Center and released by the Maine People’s Alliance (of which Beacon

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Oct 6 • 4:17 PM EDT • Health • mainebeacon.com
SUN: Orioles make layoffs within business ops ahead of expected MLB lockout

The Orioles laid off multiple employees from their business operations department Tuesday, according to an internal memo obtained by The Baltimore Sun that pres

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Oct 6 • 4:00 PM EDT • Business • foxbaltimore.com
Thune presses Trump for more funding toward battleground races red

Senate Majority Leader John Thune (R-SD) on Monday revealed he is pressing President Donald Trump for more funding toward battleground races in the midterm elections, as Republicans fight to stave off losses in November. Thune said that he’s been emphasizing the question of resources for candidates during conversations with Trump and the president’s advisers, in […]

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Oct 6 • 3:35 PM EDT • Politics • coloradopolitics.com
New Mexico behavioral health committee meets goal of approving all 13 regional health plans

The committee overseeing New Mexico's efforts to rebuild behavioral health infrastructure hit a milestone by approving all 13 regional plans.

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Oct 6 • 2:44 PM EDT • Health • sourcenm.com
Benson HS teen faces new hearing after release to mental health treatment

A 15-year-old accused of bringing dangerous chemicals to Benson High School is expected to be back in court Tuesday, where prosecutors could ask a judge to send

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Oct 6 • 2:34 PM EDT • Health • katu.com
Eyewitness News 'Health Alert' for October 4, 2026
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Oct 6 • 2:30 PM EDT • Health • bakersfieldnow.com
Science, resource chief for NPS honored with accesibility award

Steven Kidd, chief of Science and Resource Management at Timucuan Ecological and Historic Preserve in Jacksonville, Fla., was recently recognized with the Accessibility Achievement Award by the National Parks Service.

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Oct 6 • 2:29 PM EDT • Science • leader-call.com
Justice Department tells employees to adopt Trump’s AI rebrand

“This directive shall extend to court filings when appropriate,” the memo titled Super Intelligence states, sources told NBC News.

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Oct 6 • 2:19 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Former Texas Health Resources executive named to lead Blue Zones

Blue Zones, the global leader in longevity research and helping people live longer, healthier lives, announced today the appointment of Brett McClung as

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Oct 6 • 2:12 PM EDT • Health • fortworthreport.org
Idaho finalizes 2027 premium rates for individual and small-group health plans

The Idaho Department of Insurance finalized 2027 premium rates for individual and small group health insurance plans.According to a recent news release, premium

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Oct 6 • 2:10 PM EDT • Health • idahonews.com
Groves Pecan Festival kicks off this week with food, rides and entertainment
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Oct 6 • 2:07 PM EDT • Entertainment • kfdm.com
Baptist Health to provide free flu vaccines at Goodwill locations this November

Baptist Health and Goodwill of Arkansas are teaming p to provide free flu shots to community members this fall.

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Oct 6 • 2:04 PM EDT • Health • katv.com
Investment in Shelby's business district will cost roughly $5 million

Shelby will start crafting legislation for a revitalization district, with businesses announcing their expansion to the city.

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Oct 6 • 2:00 PM EDT • Business • richlandsource.com
ODNR Invites Ohioans to Celebrate Earth Science Week 2026

Article presented by Litter Quality Propane and Hometown Motors, Inc … COLUMBUS, Ohio – The Ohio Department of Natural Resources (ODNR) Division of Geological Survey is celebrating Earth Science Week from Sunday, October 11, through Saturday, October 17. Four special events will be offered throughout Ohio and will coincide with the annual national celebration. “We […]

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Oct 6 • 1:49 PM EDT • Science • littermedia.com
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New Mexico Health Care Authority creates shareable resources about Medicaid changes

NEW MEXICO (KRQE) – The New Mexico Health Care Authority has launched a Medicaid Partner Toolkit to help community organizations, health care providers, advocates and other partners explain upcomin…

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Oct 6 • 1:20 PM EDT • Health • krqe.com
Broker facilities expand as technology, alternative capital reshape placements

Broker facilities that automatically or rapidly provide following capacity are expanding as brokers seek to speed placements, use data to package portfolios of risks and tap additional sources of…

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Oct 6 • 1:14 PM EDT • Business • businessinsurance.com
STAR WARS: Galactic Racer — Crashing with Consequence in Runs-Based Racing

Why wrecking out in STAR WARS: Galactic Racer, available today on XBOX Series X|S, is an essential part of the experience.

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Oct 6 • 12:00 PM EDT • Technology • news.xbox.com
Metallica’s Sphere debut headlines a big Las Vegas entertainment weekend
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Oct 6 • 11:51 AM EDT • Entertainment • news3lv.com
Idaho drought-hit businesses offered low-interest disaster loans

The U.S. Small Business Administration announced low-interest federal disaster loans for eligible small businesses and private nonprofit organizations in Idaho

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Oct 6 • 11:30 AM EDT • Business • idahonews.com
HealthSource, UC Health team up on new medical facility in Batavia

HealthSource of Ohio and UC Health are partnering on a project that will bring both organizations' services together under one roof in Batavia.

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Oct 6 • 11:21 AM EDT • Health • cincinnati.com
Gears of War: E-Day - Surviving the First Night of Emergence

Today marks the worldwide launch of Gears of War: E-Day, now available on XBOX Series X|S, XBOX on PC, Game Pass and Steam. One of XBOX’s most iconic sagas returns to where it all began, taking players back to the opening hours of Emergence Day and the catastrophic event that changed the world of Sera […]

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Oct 6 • 11:00 AM EDT • Technology • news.xbox.com
Data science professor awarded grant to support partnership with Internet Archive, preserve digital history

Alexander Nwala will develop AI models that automatically identify, archive and catalog web resources referenced in U.S. television news in a publicly accessible database.

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Oct 6 • 9:26 AM EDT • Science • news.wm.edu
Block Club Chicago’s Free South Side Health & Wellness Fest Is Coming to Chatham

Join Block Club and community partners on Nov. 7 for activities and resources to help address health equity gaps. Join a fun run with Joabe Barbosa, get a free meal and more.

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Oct 6 • 9:00 AM EDT • Health • blockclubchicago.org
As U.S. Cybercrime Losses Top $20 Billion, Bank of America Expands Fraud Education for Small Business Owners

New Educational Tools, Fraud-Prevention Resources and Webinars Aim to Help Entrepreneurs Protect Their Businesses From Increasingly Sophisticated Scams Key...

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Oct 6 • 9:00 AM EDT • Business • prnewswire.com
HEALTH WATCH: Staying Healthy For Breast Cancer Awareness Month
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Oct 6 • 8:30 AM EDT • Health • foxbaltimore.com
New Report: 400+ Global Life Science Leaders Bullish Despite Market Uncertainty

As AI usage takes shape and market pressures persist, CRB's Horizons: Life Sciences 2026 report explores how manufacturers are investing in facilities,...

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Oct 6 • 8:05 AM EDT • Science • globenewswire.com
How traditional Chinese medicine is shaping Kazakhstan’s health system

Partnership is latest move by Beijing to engage the resource-rich country amid expanded ties in energy, security, trade and infrastructure.

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Oct 6 • 8:04 AM EDT • Health • scmp.com
Small business incentives face final vote as Nashville owners want broader relief

Nashville leaders could give the Mayor's small business incentives a final stamp of approval tonight as local spots struggle with higher expenses across the boa

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Oct 6 • 8:00 AM EDT • Business • fox17.com
Trump says Iran can 'take out' LA or San Diego during political rally

President Donald Trump faces backlash for saying Iran could 'take out' Los Angeles and San Diego as a 'small price to pay' during Nebraska rally. (Source: POOL)

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Oct 6 • 7:59 AM EDT • Politics • wbrc.com
Trump says Iran can 'take out' LA or San Diego during political rally

President Donald Trump faces backlash for saying Iran could 'take out' Los Angeles and San Diego as a 'small price to pay' during Nebraska rally. (Source: POOL)

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Oct 6 • 7:59 AM EDT • Politics • fox5vegas.com
FT and Standard Chartered Book of the Year Award 2026

Contenders include titles on weight-loss drugs, AI weaponry and forecasting

ft.com logo
Oct 6 • 7:20 AM EDT • Technology • ft.com
FT and Standard Chartered Book of the Year Award 2026

Contenders include titles on weight-loss drugs, AI weaponry and forecasting

ft.com logo
Oct 6 • 7:20 AM EDT • Business • ft.com
DC council to decide whether businesses can pay for extra parking enforcement
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Oct 6 • 6:21 AM EDT • Business • wjla.com
How can Mainers stop political campaign text messages?
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Oct 6 • 6:16 AM EDT • Politics • wgme.com
Mental Health Resource Fair coming to Victorville

The city of Victorville will partner with San Bernardino County agencies and regional service providers to host a Mental Health Resource Fair.

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Oct 6 • 6:04 AM EDT • Health • vvdailypress.com
Sources: Rangers can seal 'easy' Oskar Fallenius deal

Football Insider exclusive as Djurgarden winger Oskar Fallenius is in action, while Rangers manager Derek McInnes watches from a circular inset.

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Oct 6 • 3:16 AM EDT • Sports • sports.yahoo.com
Red snapper season opens Friday; anglers can donate carcasses for science and prizes

MOREHEAD CITY, N.C. — Recreational anglers will have three days to harvest red snapper this weekend, and North Carolina fisheries officials are asking them to c

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Oct 6 • 3:07 AM EDT • Science • wcti12.com
The politics of losing sleep

There is still a class divide when it comes to work that tramples over your body clock

ft.com logo
Oct 6 • 12:00 AM EDT • Politics • ft.com
Kalamazoo Public Schools approves resolutions for school safety funding

Kalamazoo Public Schools' Board of Trustees has approved resolutions that would provide them with school safety funding from the state.

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Oct 5 • 11:21 PM EDT • Health • wwmt.com
'Stop playing politics': Ginther, Council trade barbs over $2.5M Barack Center repairs

A fight over $2.5 million in repairs to a tornado-damaged Southside community center has escalated into a public political clash between Columbus Mayor Andrew G

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Oct 5 • 9:23 PM EDT • Politics • abc6onyourside.com
The Xbox Elite Controller (Series 3) specs might've leaked — here's what's new (and the main thing you'll want to know remains unanswered)

Although I was unable to verify the sources (as they've been removed), users suggest that this leak is most likely legit. The Xbox Elite Controller Series 3 is likely imminent.

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Oct 5 • 9:01 PM EDT • Technology • windowscentral.com
Countries race to provide oral health care for all in 100-Day Sprint across Asia

Twenty Asian countries and areas across the WHO Western Pacific and South-East Asia regions vowed to strengthen essential oral health benefits as part of a “100-Day Sprint” initiative, during the 16th Asian Chief Dental Officers Meeting held from 27 to 29 September in Kota Kinabalu, Malaysia. The meeting marked the midpoint of the 100-day sprint bolstering support for countries to develop essential oral health benefit packages that can be integrated into national universal health coverage plans. Convened by the two WHO regional offices and the Malaysian Ministry of Health as the Secretariat, the meeting brought together national oral health leaders from 20 Asian countries, staff from all levels of WHO, WHO collaborating centres and other development partners. Participating countries and areas included: Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Hong Kong (SAR) China, India, Indonesia, Japan, Lao People’s Democratic Republic, Malaysia, Maldives, Mongolia, Nepal, the Philippines, Singapore, Sri Lanka, Thailand, Timor-Leste and Viet Nam. Participants reviewed progress and refined proposals using the WHO Service Package Delivery and Implementation (SPDI) Platform. Countries conducted bottleneck analyses across four key areas: service delivery, workforce, access to essential medicines and health products, and health financing. They identified practical actions to address implementation challenges and refined proposed revisions to their national oral health benefit packages. “There is no health without oral health. Through the 100-Day Sprint, countries are advancing the implementation of the Western Pacific regional implementation plan on oral health and strengthening progress towards universal health coverage,” noted WHO Regional Director for the Western Pacific Dr Saia Ma'u Piukala. Participants identified bottlenecks and proposed workable solutions to strengthen access to essential oral health care through primary health care, sharing experiences and discussing how best to translate policy commitments into feasible and sustainable action at the country level. Malaysian Minister of Health Datuk Seri Dr Dzulkefly Ahmad highlighted the importance of prevention and primary health-care approaches to improve oral health: “Oral diseases can have lifelong consequences, yet many are preventable. By integrating essential oral health care into primary health care and promoting prevention in schools and communities, we can improve oral health across the life course.”The WHO team led by Dr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control of the WHO Western Pacific Region and national oral health leads from over 20 Asian countries visited the SK Pekan Putatan School, Sabah for school oral health programme including flouride mouth rinsing. © WHO / V. ChaudharyDr Huong Tran, Director of the Division of Health Promotion, Disease Prevention and Control for the WHO Western Pacific Region, emphasized key collaborative roles WHO can play. “Oral diseases are the most common noncommunicable diseases, yet many can be prevented and treated through essential oral health services delivered at the primary health-care level,” she said. “By sharing experiences and using WHO tools such as the SPDI Platform, countries are accelerating progress towards universal health coverage for oral health.” “Integrating oral health into broader health services is essential for reducing inequities, expanding access and recognizing oral health as an integral component of overall health and well-being. The 100-Day Sprint provides an important opportunity to translate this commitment into practical action and ensure that quality oral health services reach all people, especially those most in need,” said Dr Suman Rijal, Director of the WHO South-East Asia regional Department of Healthier Populations and Noncommunicable Diseases. As host of the meeting, Malaysia showcased ongoing efforts to strengthen oral health care through primary health care and prevention-focused approaches, while providing a platform for countries across the two WHO regions to exchange experiences and accelerate progress towards universal health coverage for oral health. “WHO is encouraged by Malaysia's leadership in addressing the burden of oral diseases and advancing universal health coverage for oral health through practical, country-led action,” said Dr Rabi Abeyasinghe, WHO Representative to Malaysia, Brunei Darussalam and Singapore. Countries will continue to refine and figure costs for national oral health benefits during the remaining sessions of the 100 days. These efforts support implementation of the WHO Global strategy and action plan on oral health 2023–2030, while also helping to expand access to essential oral health services through stronger and more equitable health systems across the WHO Western Pacific and South-East Asia regions.______________For more information, or to arrange media interviews, contact: WHO Regional Office for the Western Pacific: wprocom@who.int WHO Regional Office for South-East Asia: SEMediaRelations@who.int

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Oct 5 • 8:00 PM EDT • Health • who.int
2026 UHC Day campaign launch

The 2026 UHC Day campaign launch will give advocates, including civil society and young people, tools and messaging to advocate for universal health coverage and hold decision-makers to account for their global commitments.

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Oct 5 • 8:00 PM EDT • Health • who.int
Arkansas veteran battling leukemia fights to restore health insurance
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Oct 5 • 7:45 PM EDT • Health • katv.com
Authorities ID body of man found behind Fairview business

Authorities identified the man found dead behind a Fairview, Oregon business as 49-year-old Kerry Cottrell. Investigators suspect a medical condition, with the medical examiner to confirm cause and manner of death.

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Oct 5 • 7:43 PM EDT • Business • katu.com
On the Money: Tips for starting a small business
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Oct 5 • 7:22 PM EDT • Business • kval.com
'Tacoma isn’t safe’: Downtown businesses call for action after double homicide

Tacoma police are investigating after two men were shot and killed downtown just before 12:30 a.m. Sunday.

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Oct 5 • 7:03 PM EDT • Business • komonews.com
This tool frees up Apple Intelligence storage on macOS, but think twice before using it

A new open-source tool is going viral over its promise to let users who aren’t interested in Apple Intelligence reclaim 12GB or more of storage on their Macs.

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Oct 5 • 6:55 PM EDT • Technology • 9to5mac.com
Hawaiʻi Island program bridges the gap between food and health

Through a partnership with the Hawaiʻi Island Community Health Center and the Food Basket, the initiative provided 25 patients with weekly food boxes that are completely locally sourced to measure how regular access to healthy, local foods would impact their overall health.

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Oct 5 • 6:42 PM EDT • Health • hawaiipublicradio.org
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Emory & Henry, Appalachian Independence Center host inaugural Healthy Aging Fair
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Oct 5 • 6:21 PM EDT • Health • wcyb.com
Cincinnati nuisance business rules for late-night bars face fierce opposition

A proposed crackdown on Cincinnati’s so-called nuisance businesses has put City Hall at odds with some late-night bar and nightclub owners.

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Oct 5 • 5:38 PM EDT • Business • local12.com
Hamilton County health officials urge families to update vaccines ahead of flu season

As flu season approaches, the Hamilton County Health Department is renewing its warning for families to make sure they are protected with the most current vacci

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Oct 5 • 5:12 PM EDT • Health • newschannel9.com
Alexandria health official urges flu shots as season arrives, warns flu can be serious
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Oct 5 • 4:37 PM EDT • Health • wjla.com
Richland County Mental Health & Recovery Services Board selects Aubrie Hall new director

Aubrie Hall most recently served as executive director of NAMI Richland County, a post she held for two and a half years.

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Oct 5 • 4:15 PM EDT • Health • richlandsource.com
FSU becomes first college campus to install interactive Hope Booth to support student mental health

Florida State University has become the first college campus in the nation to install a Hope Booth, an innovative resource designed to expand access to

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Oct 5 • 3:52 PM EDT • Health • news.fsu.edu
Broker consolidation shifts from dealmaking to integration

Years of rapid consolidation in the insurance brokerage sector are giving way to a greater focus on integrating acquired firms and on finding sources of organic growth in a softening market…

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Oct 5 • 3:47 PM EDT • Business • businessinsurance.com
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.

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Oct 5 • 3:42 PM EDT • Entertainment • entertainment.substack.com
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Bladen Community College to host “So You Want to Start a Small Business” class and preview Pitch It Bladen 2027

The Small Business Center at Bladen Community College invites aspiring entrepreneurs to attend “So You Want to Start a Small Business” on Tuesday, Oct. 13, 2026, from 6:00 p.m. to 8:00 p.m. in Building 14, Room 104. This class will help participants explore what it takes to become an entrepreneur and take the first steps toward turning a business idea into reality.Participants will explore the entrepreneurial mindset and consider whether they have the interests, characteristics, motivation and willingness to take on the challenges of business ownership. The class will encourage attendees to examine their personal goals, expectations, strengths and readiness to pursue entrepreneurship.Attendees will also gain insight into the realities of starting and operating a small business, including the commitment, planning, decision-making and perseverance required to build a successful venture. Whether participants are just beginning to consider business ownership or already have an idea they want to pursue, this class will provide a foundation for determining their next steps.In addition to the class instruction, attendees will receive advance information about the upcoming Pitch It Bladen 2027 Business Competition, including the application form and details about the program. Individuals who are ready to move forward may submit their applications early and have the opportunity to receive advance acceptance into the program.Pitch It Bladen helps aspiring and emerging entrepreneurs develop their business ideas through structured instruction in business planning, financial management, cash-flow projections, marketing and operations. Participants work toward completing a business plan and preparing a business pitch, with the opportunity to compete for cash prizes.Last year's Pitch It Bladen program demonstrated the value of investing in local entrepreneurs by helping participants strengthen their business knowledge, develop their business plans and prepare to present their ideas. The competition showcased the creativity and potential of Bladen County's small-business community and provided participants with practical tools to move their business goals forward.Building on that success, Pitch It Bladen 2027 will provide another opportunity for local entrepreneurs to gain knowledge, build confidence and take meaningful steps toward launching or growing a business.“The Small Business Center wants to help individuals make informed decisions about entrepreneurship before they take the leap into business ownership,” said Theresa Dennison, Small Business Center director, in a press release. “This class gives participants an opportunity to evaluate whether entrepreneurship is right for them while also introducing them to Pitch It Bladen 2027 and the resources available to help them succeed.”Registration: Visit www.ncsbc.net and search for the class by name, or contact the Small Business Center at 910-879-5572 for additional information.

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Oct 5 • 3:26 PM EDT • Business • bizfayetteville.com
Health officials issue urgent warning after four Utah deaths tied to herbal supplements

Utah health officials issued a public health warning after four deaths across the state were linked to certain herbal supplements, including kratom products and

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Oct 5 • 2:35 PM EDT • Health • kutv.com
University of New Haven Researchers Advance Health Equity and Health-S

Research focused on health equity and health-system transformation has grown from a 2023 faculty-student project into a broad, collaborative body of scholarship involving students, faculty, health sys

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Oct 5 • 2:30 PM EDT • Health • newhaven.edu
New Trump admin. rule targets hidden health care costs as FTC puts hospitals on notice
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Oct 5 • 2:06 PM EDT • Health • komonews.com
New Trump admin. rule targets hidden health care costs as FTC puts hospitals on notice
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Oct 5 • 2:06 PM EDT • Health • kfoxtv.com
How a controversial camera system is monitoring mental health patients

The Lampard Inquiry started back in September 2024 and I remember going to the first hearing in Chelmsford. Subscribe The bereaved families made placards of their loved ones, they stood outside in silence and then laid flowers to mark the moment. Now, two years on, in a process meant to last another two years, there’s been a development. Last week, we were told the chair, Baroness Lampard, pictured below, could be looking at making interim recommendations. Throughout the process, she has remarked that although this inquiry is looking at almost 2,000 people who were under the care of Essex mental health services from 2000-2023 when they died, the findings could have national implications for other trusts. ‘Records 24 hours a day in patient’s bedroom’ So why has this happened? One system that the inquiry is going to take a closer look at is a controversial monitoring system called Oxevision. It monitors some vital signs of patients remotely by using a camera placed in a room. It’s used by 40% of NHS mental health trusts. But campaigners, particularly the group Stop Oxevision, have asked for this technology to be removed from mental health wards as soon as possible. I spoke to a member, Hat Porter, today and they described to me what they thought this technology did and explained their concerns: “It records 24 hours a day and it’s located in a patient’s bedroom, which is obviously somewhere you’d usually expect to be a private place. “Our concerns are that the use of the technology has been has been kind of implemented as a substitute for proper in-person support, that it’s kind of over relied on and that there’s a lot of misunderstandings and that the presence of a camera, which has often been used without people’s consent, sometimes without even their knowledge, that that has a really big impact on privacy, dignity and human rights.” ‘Not sufficient’ I put it to them that the company behind Oxevision would dispute their claims about consent and in videos I’ve seen online from NHS trusts, they make it clear that the technology is complementary to trained staff and not a replacement. [ ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) [ How the Nottingham inquiry shines a spotlight on other key mental health care failings ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) Victoria Macdonald · Feb 12 [ Read full story ](https://channel4news.substack.com/p/the-nottingham-inquiry-what-lessons) A team of lawyers has been working on the inquiry and with bereaved family members who have concerns about this technology. I spoke to solicitor Priya Singh, from Hodge Jones & Allen, who made the point that questions usually asked by nurses would be missing from using devices like this. “It’s not sufficient to say, oh, the patient is moving around. Somebody must go in and say, are you okay? Are you distressed? Do you want help? Is there anything I can do? Share Channel 4 News “How are you spending your time? So I think a lot of our families cannot see the function of it when ultimately the patient should only really be observed when they’ve been prescribed to be observed, they can be observed more, but that more should really be happening face to face.” The Chair will hear evidence over the next two weeks and then a decision made after that, which could have national impact if she does decide this technology should be investigated or even removed. The Department of Health and Social Care said: “The Government is committed to ensuring that lessons are learned from the Lampard Inquiry to improve patient safety. “We are confident that the Inquiry will play an important role in identifying wider learnings for the health system following the tragic events in Essex and will contribute to improvements in patient safety.” We approached LIO Health, which runs Oxevision, for comment. Subscribe Share Channel 4 News Leave a comment

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Oct 5 • 2:03 PM EDT • Health • channel4news.substack.com
OSU Center for Health Sciences raises more than $800K for wellness center, scholarships

Oklahoma State University Center for Health Sciences hosted its first Orange Impact event Thursday and raised more than $800,000 toward a new wellness center an

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Oct 5 • 1:59 PM EDT • Health • fox23.com
Planet Fitness acquires Bakersfield’s Body Xchange Health Club locations

Body Xchange Health Clubs announced that they have been acquired by Planet Fitness.The announcement was posted on their social media pages.The company said that

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Oct 5 • 1:40 PM EDT • Health • bakersfieldnow.com
Flu season is already spiking in Hamilton County local health officials say

Hamilton County health officials are urging residents to get up to date on recommended and school-required vaccinations ahead of the cold and flu season.The Ha

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Oct 5 • 1:33 PM EDT • Health • newschannel9.com
TNT Sports head Luis Silberwasser to depart Skydance as CBS Sports chief David Berson takes over combined global sports group

TNT Sports chief Luis Silberwasser will be leaving a combined Paramount Skydance-Warner Bros. Discovery company, sources tell CNBC.

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Oct 5 • 1:04 PM EDT • Sports • cnbc.com
Hello from Seattle: XBOX FanFest Comes Home November 12

Seattle, we’re coming home. XBOX FanFest is coming on Thursday, November 12, 2026 - find out what to expect and how to attend inside.

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Oct 5 • 1:00 PM EDT • Technology • news.xbox.com
Trump is clearly trying to buy votes with taxpayer money

President Donald Trump is ramping up his efforts to use taxpayer money and resources to help Republicans win the 2026 midterm elections.

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Oct 5 • 12:20 PM EDT • Politics • cnn.com
RSU and USAO partner to create Accelerated Master's Program for computer science students

Rogers State University (RSU) and the University of Science & Arts of Oklahoma (USAO) have partnered together to create an Accelerated Master's Program for comp

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Oct 5 • 12:18 PM EDT • Science • ktul.com
RSU and USAO partner to create Accelerated Master's Program for computer science students

Rogers State University (RSU) and the University of Science & Arts of Oklahoma (USAO) have partnered together to create an Accelerated Master's Program for comp

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Oct 5 • 12:17 PM EDT • Science • fox23.com
Spanish PM Pedro Sánchez looks for political lifeline in snap election

Embattled Socialist leader aims to capitalise on housing crisis to remain in power

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Oct 5 • 11:33 AM EDT • Politics • ft.com
Caring for students a priority at Health Center

A primary purpose of the Campbell University Health Center is caring for students, serving as an important resource in regard… More on this post

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Oct 5 • 11:26 AM EDT • Health • news.campbell.edu
Health care aide charged in assault of disabled resident at Halfmoon facility

A Schenectady woman working as a health care aide has been charged after State Police said a disabled resident was assaulted at a Halfmoon care facility.

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Oct 5 • 11:24 AM EDT • Health • cbs6albany.com
Misericordia University to Host Healthcare Symposium with Presenting Sponsor Geisinger

Misericordia University’s College of Health Sciences and Education, with Geisinger as Presenting Sponsor, will host the 2026 Healthcare Symposium, “Connected Care: Aligning Education, Innovation & Community Health,” on Friday, Oct. 23, from 8 a.m. to 5 p.m. in Lemmond Theater on the University’s Dallas campus.

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Oct 5 • 11:10 AM EDT • Health • misericordia.edu
Metallica rides the lightning with Sphere residency debut
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Oct 5 • 11:05 AM EDT • Entertainment • news3lv.com
The Science Enabling a Steady Supply of Critical Minerals

Researchers are collaborating across disciplines to unlock domestic sources of valuable materials and lower costs.

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Oct 5 • 11:00 AM EDT • Science • newscenter.lbl.gov
Senate Unanimously Passes the Health Care Cybersecurity and Resiliency Act

A bipartisan bill that seeks to improve healthcare cybersecurity and resilience has been unanimously passed by the U.S. Senate. The bill - The Health Care The U.S. Senate has voted unanimously to advance the Health Care Cybersecurity and Resiliency Act, which requires more robust cybersecurity measures for healthcare organizations and authorizes grants to help rural and under-resourced providers improve cybersecurity.

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Oct 5 • 10:06 AM EDT • Health • hipaajournal.com
Paid influencers and political ads - Illinois Times, the capital city's source of news, politics, arts, entertainment, culture

My associate Isabel Miller and I worked on a story last week about paid influencers in campaigns. We decided to look into it after reading news reports about how the Chicago Teachers Union has been using paid influencers in its battle to control the elected Chicago school board and Chicago Mayor Brandon Johnson is also […]

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Oct 5 • 10:04 AM EDT • Politics • illinoistimes.com
An open-source tool lets you delete 12GB of Apple Intelligence data on macOS

Delete Apple’s AI with a single command.

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Oct 5 • 9:47 AM EDT • Technology • theverge.com
NAMI Central Florida highlights mental health resources during Mental Illness Awareness Week

Freddy Morello Jr., CEO of NAMI Central Florida, discusses free resources, new programs, and an upcoming gala during Mental Illness Awareness Week.

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Oct 5 • 9:46 AM EDT • Health • wesh.com
Flathead City-County Health Department to hold annual flu clinic

The Flathead City-County Health Department will hold its annual flu clinic Wednesday, Oct. 7, at the Flathead County Fairgrounds Expo Building.The clinic will r

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Oct 5 • 9:11 AM EDT • Health • nbcmontana.com
Cal-Maine cracks open new growth opportunities

Earnings plunge amid low egg prices and investments in prepared foods.

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Oct 5 • 8:23 AM EDT • Business • foodbusinessnews.net
Heartland Catfish Unveils New Website

Heartland Catfish Company recently launched a new website in celebration of its 30th anniversary. The site has been refreshed to focus on retail and food service partnerships, give a detailed look at the company’s products and processes and emphasize consumer education about the benefits of U.S. Farm-Raised Catfish as a versatile and healthy protein source. […]

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Oct 5 • 8:04 AM EDT • Business • deltabusinessjournal.com
KUNC's 2026 midterm election voter guide for Northern Colorado

Everything Northern Colorado voters need to know about the state’s midterm election, including major races, ballot measures, voting deadlines, how to return your ballot, and where to find trusted election resources.

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Oct 5 • 8:00 AM EDT • Politics • kunc.org
Mac Users Reclaim Storage With New Apple Intelligence Removal Tool

A new open-source tool is making waves in the Mac community by helping users reclaim valuable storage space taken up by Apple's AI models. Called "RemoveMacAI," the tool disables Apple Intelligence on macOS 27, removes its downloaded models, and prevents them from being downloaded again. In macOS 27, Apple removed the toggle to disable Apple Intelligence wholesale, and simply disabling individual features doesn't remove the models from your Mac's drive.

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Oct 5 • 7:12 AM EDT • Technology • macrumors.com
Jobs in health care. Jobs for women. The US labour market is segmenting. Chernobyl’s radiation and Lenin’s love of literature.

Thank you for opening your Chartbook email. Elmer Bischoff, Two Figures at the Seashore, 1957 The only really dynamic job-creator in the US economy is health care: The largest crunch has come in Federal government, which has shed 2.7 m jobs. Source: tchouvkov on Twitter Tech is struggling. [ Joey Politano 🏳️‍🌈@JosephPolitano The US tech sector continues bleeding jobs in official data released today—overall, employment decreased by 17k last month and is down 69k over the last year That's nearly as bad as the worst of the 2024 tech-cession, and much worse than the 2022 boom or even pre-2020 norms 12:42 PM · Oct 2, 2026 · 15.2K Views 15 Replies · 47 Reposts · 390 Likes ](https://x.com/JosephPolitano/status/2106001807847940232?s=20) The new jobs are all for women. [ Justin Wolfers@JustinWolfers I'm not sure who saw this coming, but so far nearly all the jobs created during the second Trump administration have gone to women. 1:09 PM · Oct 2, 2026 · 33K Views 70 Replies · 146 Reposts · 644 Likes ](https://x.com/JustinWolfers/status/2106008723533533601?s=20) Meanwhile, real wages are being eaten up by modest over-target inflation. [ Heather Long@byHeatherLong The financial pain is real: Wage growth fell to 3% (y/y) in September. That's the lowest in 5 years. Wage growth: 3% Inflation: ~3.4% Inflation has eaten up all wage gains for the average worker since April. Many people are having to make hard choices about what to buy and what … 1:24 PM · Oct 2, 2026 · 37K Views 24 Replies · 275 Reposts · 533 Likes ](https://x.com/byHeatherLong/status/2106012367712620728?s=20) HEY READERS, THANK YOU for opening the Chartbook email. I hope it brightens your day. I enjoy putting out the newsletter, but tbh, what keeps this flow going is the generosity of those readers who clicked the subscription button. If you are persuaded to click, please consider the annual subscription of $60. It is both better value for you and a much better deal for me, as it involves only one credit card charge. Why feed the payments companies if we don’t have to. Subscribe Elmer Bischoff, Bathers, 1960 Americans are disillusioned with higher ed. For contributing subscribers only. Subscribe Where the Chernobyl radiation went. h/t Simon Kuestenmacher aka simongerman600 How Lenin’s love of literature shaped the Russian Revolution - Tariq Ali This, then, was the intellectual atmosphere in which Lenin came of age. His father, a highly cultured conservative, was the chief inspector of schools in his region and much respected as an educationalist. At home, Shakespeare, Goethe and Pushkin, among others, were read aloud on Sunday afternoons. It was impossible for the Ulyanov family – “Lenin” was a pseudonym adopted to outwit the tsarist secret police – to escape high culture. At high school, Lenin fell in love with Latin. His headteacher had high hopes that he might become a philologist and Latin scholar. History willed otherwise, but Lenin’s passion for Latin, and taste for the classics, never left him. He read Virgil, Ovid, Horace and Juvenal in the original, as well as Roman senatorial orations. He devoured Goethe during his two decades in exile, reading and rereading Faust many times. Lenin put his knowledge of the classics to good use in the time leading up to the October revolution of 1917. In April of that year, he broke with Russian social-democratic orthodoxy and, in a set of radical theses, called for a socialist revolution in Russia. A number of his own close comrades denounced him. In a sharp riposte, Lenin quoted Mephistopheles from Goethe’s masterwork: “Theory, my friend, is grey, but green is the eternal tree of life.” Source: The Guardian Elmer Bischoff, The River, 1953 If you’ve scrolled this far, you know you want to click: Subscribe

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Oct 5 • 6:47 AM EDT • Health • adamtooze.substack.com
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth

Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine

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Oct 5 • 6:44 AM EDT • Science • goldrushcam.com
Is a ‘political’ email sent with county government resources worth a $5K fine?

Republican County Councilman Nathan Volke is championing three ethics reforms for Anne Arundel County government, with just weeks to go before the election. What’s he hoping to accomplish? How could county government actually change?

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Oct 5 • 5:30 AM EDT • Politics • thebanner.com
BagelUp Growth Lab Returns as Business Incubator for Emerging Bagel Entrepreneurs, Launching a Year-Round Partner Program

Great bagels may start with flour, water, yeast and skill, but building a successful bagel business takes much more. On Saturday, November 14th, 2026, BagelUp (which produces New York BagelFest) will present the second annual BagelUp Growth Lab, a business incubator designed to help promising bagel entrepreneurs gain the knowledge, connections and industry resources needed to turn their bagel concepts into sustainable businesses. Taking place at Loft 39 the day before New York BagelFest at Citi

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Oct 5 • 5:00 AM EDT • Business • finance.yahoo.com
Silicon Valley hottest funding source: the Bank of Best Friends

As big money deals in venture capital dry up, tech founders are asking mom, dad, and friends to open their wallets.

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Oct 5 • 4:07 AM EDT • Business • businessinsider.com