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Makana Eyre: Polynesian Health Overlooked In Buzz Over Landmark Study

The study provided insights into the origins of Native Hawaiians. More consequential is what this “genetic treasure trove” means for people with rare DNA mutations.

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Oct 26 • 6:01 AM EDT • Health • civilbeat.org
LSU’s Project Wellness Club provides students with resources for mental, physical health

The LSU Project Wellness Club hosted pumpkin painting and spooky movie night on Thursday, which was just one of the many events the club puts on for students to de-stress and have an on campus outlet. The club focuses on students’ mental health. Co-president and psychology senior Lindsey Puente describes the club as collaborative, saying...

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Oct 26 • 6:00 AM EDT • Health • lsureveille.com
Exclusive: Health tech PE megadeals surge as deal volume drops

The average health care buyout size jumped to $3.4 billion in the first half of 2026.

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Oct 26 • 6:00 AM EDT • Health • axios.com
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Did a Milwaukee County health insurance contract lapse under David Crowley’s administration?

Yes. Crowley fired a top human resources official after the official admitted to the error.

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Oct 26 • 6:00 AM EDT • Health • wisconsinwatch.org
Islanders News: Did not do Dallas

The Islanders were leaky all over in Dallas, almost like they have a declining defense outside of Matthew Schaefer. The 6-3 loss to the Stars was not surprising overall, but it did end a modest points streak and exposed some holes that Pete DeBeor has been working to cover. Islanders News Elsewhere

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Oct 26 • 6:00 AM EDT • Sports • sports.yahoo.com
Need help deciding on the state ballot measures? Here are my recommendations

You haven’t voted yet because the state propositions are too bewildering? I’m with you.

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Oct 26 • 6:00 AM EDT • Politics • latimes.com
News Analysis: Trump says he's trying to entice Russia to negotiate. It doesn't appear to be working

Trump's break from long-standing tradition in U.S.-Russia relations was real, but it should not have been entirely surprising.

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Oct 26 • 6:00 AM EDT • Politics • latimes.com
Canadian political party leader blames BioWare's closure on private equity, says government should help former employees buy it back

Avi Lewis, head of the Canadian NDP party, has expressed support for employees laid off by EA last week, and spoke out about the perils of private equity.

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Oct 26 • 5:53 AM EDT • Technology • eurogamer.net
Michigan Medicine’s new AI chief joins a fast-growing club of hospital executives​

The fast-paced ramp-up of AI and financial pressures have health systems scrambling to find an executive to oversee adoption and implementation.

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Oct 26 • 5:45 AM EDT • Health • crainsdetroit.com
Michigan Medicine’s new AI chief joins a fast-growing club of hospital executives​

The fast-paced ramp-up of AI and financial pressures have health systems scrambling to find an executive to oversee adoption and implementation.

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Oct 26 • 5:45 AM EDT • Business • crainsdetroit.com
How Beacon Health System Closed an 8,000-Patient Care Gap in Under Eight Weeks

Beacon Health System used agentic AI to reach 8,000 overdue patients, improve colorectal cancer screening and generate measurable ROI.

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Oct 26 • 5:00 AM EDT • Health • modernhealthcare.com
The Cost of Healthcare Is Hitting America Where It Hurts: The Wallet

Rising healthcare costs are upending the lives of Americans. People are forgoing health insurance, rationing medications, cutting back on doctor visits, and putting off health procedures they can’t afford. But bringing the costs down won’t be easy.

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Oct 26 • 5:00 AM EDT • Health • kffhealthnews.org
115-year-old Pan-American Life Insurance Group on track to surpass $2B in revenue

Insurance industry veteran José Suquet's bags were nearly packed for a job in Miami in 2004 when recruiters looking to fill the top job at Pan-American Life Insurance Group in

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Oct 26 • 5:00 AM EDT • Business • nola.com
Divided nation: Republicans prize patriotism, Democrats equality-Poll

As crucial midterms loom, a Gallup/With Honor survey found no consensus that basic American values are shared across party and other lines.

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Oct 26 • 4:53 AM EDT • Politics • usatoday.com
Pa., N.J. and Del. to kick off 2027 ACA health insurance open enrollment on Nov. 1 as health costs rise: What you should know

ACA customers may face higher premium prices for coverage next year, but insurance experts say most people still qualify for financial assistance.

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Oct 26 • 4:00 AM EDT • Health • whyy.org
Texas adopts new water disclosure for land sales

Texas now requires many land sellers to disclose groundwater and surface water rights before closing a land sale under Texas Real Estate Commission rules.

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Oct 26 • 2:40 AM EDT • Business • farmprogress.com
Cole Caufield’s Canadiens claim will surely divide fans across Canada

The Montreal Canadiens are having a fine start to the 2026-27 NHL season. Cole Caufield and his teammates are looking to return to the Stanley Cup Playoffs. In outdoor conditions on Sunday, Caufield was a big star for the Habs against the Winnipeg Jets. The Canadiens defeated the Jets 2-1 in the Heritage Classic at Princess Auto Stadium in […] The post Cole Caufield’s Canadiens claim will surely divide fans across Canada appeared first on ClutchPoints.

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Oct 26 • 2:39 AM EDT • Sports • sports.yahoo.com
Getting health insurance from your job will be extra pricey for 2027

Workers might start feeling faint when they sign up for work-based health coverage for 2027. Premiums are expected to skyrocket for the fourth year in a ...

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Oct 26 • 2:00 AM EDT • Health • toledoblade.com
Franciscan Health receives stuffed animals for pediatric patients across Northwest Indiana

NORTHWEST INDIANA — Pediatric patients in Franciscan Health emergency rooms, pediatric inpatient units and outpatient surgery centers in Michigan City, Chesterton, LaPorte, Dyer and Munster will now have stuffed animals to help make their hospital experience a little more comfortable, thanks to a donation by The Eva Martin Project. Representatives from The Eva Martin Project recently donated more than 1,400 new stuffed animals to the nonprofit Catholic healthcare system during a drop-off at Franciscan Health Michigan City. Each item has a tag with the organization’s logo and a QR code with a personal message on the back. The nonprofit organization

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Oct 26 • 1:10 AM EDT • Health • wimsradio.com
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Sports Equinox viewing guide: How to watch every NFL, MLB, NBA, NHL, WNBA game on busiest sports day of the year

The sports equinox will fall upon Monday night this year. Make sure you make arrangements to follow along.

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Oct 26 • 1:00 AM EDT • Sports • sports.yahoo.com
How to Manage Symptoms of Heart Failure

(Feature Impact) Americans are facing a growing health challenge, with 1 in 4 adults at risk of heart failure, according to the Heart Failure Society of America. Additionally, approximately 6.7 million U.S. adults who are 20 years old or older are currently living with heart failure, and that number is projected to reach 8.7 million by 2030. googletag.cmd.push(function() { googletag.display('JGFI_Article_300x250'); }); Managing heart failure is a significant expense to the U.S. healthcare system, costing the nation approximately $40 billion in 2020 and expected to increase to approximately $142 billion a year by 2050.If you (or a loved one) are living with the condition, consider these tips to help manage it.Adhere to the Treatment and Follow-Up PlanOngoing outpatient care is important when managing heart failure. Understand the treatment plan provided by your healthcare team, make diet and lifestyle changes, take medications as directed and keep recommended follow-up appointments.Pay attention to changes in symptoms and communicate with your healthcare provider if treatment does not seem to be working as expected. If their conditions are left unmanaged, patients can experience a range of heart-failure-related symptoms such as shortness of breath, fatigue, buildup of fluid and more.Understand Challenges with Diuretic TreatmentDiuretics help the body remove excess fluid and are commonly used to treat swelling, or edema, associated with heart failure. Your provider may try different diuretics, sometimes referred to as “water pills,” to manage your heart failure symptoms. However, intravenous (IV) diuretic therapy may be required for some patients if symptoms continue.Ask About Treatment Options Before IV Care Is NeededFor some adults, a healthcare provider may consider recommending an at-home, non-oral diuretic option prior to escalating to IV therapy.For example, ENBUMYST™ (bumetanide nasal spray) is a prescription diuretic used in adults to treat edema associated with congestive heart failure. It’s administered as a nasal spray for short-term use to manage excess fluid with the goal of transitioning to oral diuretic therapy when appropriate.Talk with your healthcare provider to learn more and visit enbumyst.com. Read the full Prescribing Information and Patient Information.Photo courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('JGFI_Article2_300x250'); }); Important Safety InformationWhat is ENBUMYST?ENBUMYST is a prescription medicine used in adults to treat swelling caused by excess fluid in the body (edema) from congestive heart failure, liver disease, and kidney disease.What is the most important information I should know about ENBUMYST?ENBUMYST is a diuretic that helps your body remove fluid. Losing too much fluid can cause dehydration, low blood volume, and increase the risk of blood clots. Blood abnormalities may include decreased salts (electrolytes), and increased nitrogen, glucose and uric acid. The risk of these abnormalities is higher in elderly people, those using higher doses, or those who do not get enough electrolytes by mouth.You should not use ENBUMYST if you have severe electrolyte loss. Tell your healthcare provider if you experience unusual thirst; dizziness or lightheadedness; weakness or tiredness; fast heart rate; dry mouth or tongue; sudden pain; redness or swelling in your joints; pain, swelling, redness, or warmth in your leg; shortness of breath or fast breathing; high blood sugar; dark urine; pale, tight, cool or clammy skin; muscle cramps; confusion.Do not use ENBUMYST if you have low or no urine production or are allergic to bumetanide or to any of the ingredients in ENBUMYST.Before using ENBUMYST, tell your healthcare provider if you have low electrolytes, are on a low-salt diet, have diarrhea, diabetes, nasal problems such as a runny or stuffy nose or polyps, a history of nasal injury or surgery, are or plan to become pregnant, are or plan to breastfeed.Tell your healthcare provider about all the medicines you take, including prescriptions, over-the-counter medicines, vitamins, and herbal supplements.ENBUMYST may cause serious side effects, such as worsening kidney function and ringing in the ears or hearing loss.The most common side effects of ENBUMYST include dehydration, headache, muscle cramps, dizziness, low blood pressure, nausea, and abnormal brain functioning with certain liver problems.These are not all the possible side effects of ENBUMYST. Talk to your healthcare provider for more information.Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.US-ENBU-2600110 googletag.cmd.push(function() { googletag.display('JGFI_Article3_300x250'); });

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Oct 26 • 1:00 AM EDT • Health • journalgazette.net
‘Resident Evil’ film resurrects horror game franchise

The first “Resident Evil” game came out in 1996, and since then, the franchise has been working to bring zombies, creatures and deadly outbreaks to life. For the newest piece,

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Oct 26 • 1:00 AM EDT • Entertainment • valpotorch.com
‘End game’: Taylor Swift and Travis Kelce mocked by opponent

The Seattle Seahawks handed the Kansas City Chiefs their first loss of the season on Sunday night, and they made sure to rub it in afterward by trolling newlyweds Travis Kelce and Taylor Swift. After their 20-3 win on Sunday Night Football, the Seahawks posted a Swift-themed troll on social media, sharing a friendship bracelet…

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Oct 26 • 12:40 AM EDT • Sports • sports.yahoo.com
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New York Rallies for Health and Healing

United Hospital Fund and the American Cancer Society each celebrated their own heroes this October — doctors, philanthropists, and survivors alike — in two galas united by one cause: a healthier New York.

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Oct 26 • 12:00 AM EDT • Health • newyorksocialdiary.com
Palisades setbacks put nuclear safety culture in the underwriting spotlight

A regulator's warning over a fearful workplace at Michigan's restarting reactor lands just as data-center demand pulls more insurers toward atomic risk

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Oct 25 • 11:59 PM EDT • Business • insurancebusinessmag.com
West Greene Insurance & Tax Service joins GCP

Click here to view this article from greenevillesun.com.

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Oct 25 • 11:30 PM EDT • Business • greenevillesun.com
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Ewa Beach shooting survivor overcomes another health scare

Three years after surviving a gunshot to the head, Richianna DeGuzman is heading back to rehab following a week-long stay in the ICU.

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Oct 25 • 11:24 PM EDT • Health • hawaiinewsnow.com
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Community members speak out during tense mental health advisory board meeting

Community members impacted by the withdrawal of Kings View services shared concerns during a mental health advisory board meeting last week, saying the closure of a local mental health center had left gaps in care. Board members also navigated a number of other tense moments during the meeting.

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Oct 25 • 11:20 PM EDT • Health • shastascout.org
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How Do the Blazers Stop Luka Doncic?

Fresh off a 2-0 start, Portland faces a 52-point fireball in Los Angeles. To survive, the Blazers must stifle the high pick-and-roll while shielding their smaller guards.

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Oct 25 • 11:15 PM EDT • Sports • sports.yahoo.com
Petr Yan says private political talk with Merab Dvalishvili may surface

Petr Yan discussed politics with Merab Dvalishvili soon after their five-round title clash.

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Oct 25 • 10:47 PM EDT • Politics • sports.yahoo.com
Pocatello business owner helps families impacted by Extreme Rush closure still get their night of fun

POCATELLO — When Extreme Rush suddenly closed and families were left holding gift cards meant for birthdays and special nights out, it didn’t sit right with Sloan Dalley.

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Oct 25 • 10:36 PM EDT • Business • idahostatejournal.com
Bruins’ Unbeaten Run Gets A Bigger Test Against The Hurricanes

Boston keeps finding ways to survive difficult moments, but the Bruins’ latest comeback sets up a tougher question: can they carry that resilience into a Tuesday road game against one of the NHL’s most demanding opponents?

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Oct 25 • 10:14 PM EDT • Sports • sports.yahoo.com
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Khaman Maluach Isn't Running From Massive Expectations With Suns

The current center situation in Phoenix raises the level of pressure that Maluach faces. He uses the outside noise as fuel to tangibly improve.

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Oct 25 • 10:00 PM EDT • Sports • sports.yahoo.com
Scientists Studied 96,000 Adults and Found a Surprising Exercise Longevity Benefit
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Oct 25 • 9:39 PM EDT • Science • health.yahoo.com
Vandalia Health recognized for digital health achievement

Vandalia Health earned Level 9 recognition in both acute and ambulatory care in the 2026 Digital Health Most Wired Survey.

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Oct 25 • 8:53 PM EDT • Health • mybuckhannon.com
Innovative food processing technique boosts Nebraska companies, educational outreach

Leadership and strategic visioning by Mary-Grace Danao, research associate professor in the Department of Food Science and Technology and the Department of Biological Systems Engineering, has helped position the University of Nebraska–Lincoln at the forefront of high pressure processing-focused food safety research in partnership with private industry.

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Oct 25 • 8:00 PM EDT • Science • news.unl.edu
Preparing for what’s next: Nursing insights on Future Ready Healthcare

New 2026 survey findings reveal how nurses view workforce sustainability, AI adoption, and patient communication, offering practical insights into what it takes to build a future-ready healthcare organization.

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Oct 25 • 8:00 PM EDT • Health • wolterskluwer.com
Kyle Larson’s Championship Moment Comes at Talladega

Conquering his drafting-track demons, Larson surged from mid-pack chaos to secure a historic Hendrick 1-2 finish, building a massive points cushion that places the title within reach

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Oct 25 • 7:08 PM EDT • Sports • sports.yahoo.com
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Iowa family finds strength beyond the gym after cancer diagnosis

URBANDALE, Iowa (KCCI) -- Azariah Townsend can barely reach the pull-up bar in his family’s home gym in Urbandale, but he already knows strength is not measured by height.

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Oct 25 • 7:00 PM EDT • Health • wqow.com
Matthew Stafford breaks Rams franchise record for touchdown passes

LAS VEGAS (AP) — Matthew Stafford added another milestone to his NFL career on Sunday, throwing his 155th touchdown pass for the Los Angeles Rams to break the franchise record.Stafford surpassed Roman Gabriel, who threw 154 TD passes for the Rams from 1962-72.

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Oct 25 • 6:11 PM EDT • Sports • sports.yahoo.com
A new state on the way? More Illinois counties could vote to leave Chicago behind

More than 30 counties have already approved the non-binding measure to leave Illinois

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Oct 25 • 6:06 PM EDT • Politics • yahoo.com
Democrat Coumba Kebe wants to keep the politics out of the treasurer’s office

Political newcomer Coumba Kebe is the Democratic nominee for Indiana state treasurer. Kebe wants to keep the politics out of the office and build back trust with people.

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Oct 25 • 6:03 PM EDT • Politics • purdueexponent.org
Texas Tech Takes 9-Spot Coaches Poll Hit After Cincinnati Meltdown

Texas Tech falls nine spots to No. 14 in the US LBM Coaches Poll after losing at Cincinnati, putting Joey McGuire and the Red Raiders under pressure to rebound.

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Oct 25 • 6:00 PM EDT • Sports • sports.yahoo.com
After testing all major mobile browsers, this one finally earned my default spot

Looking beyond Chrome paid off with the best browser experience

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Oct 25 • 6:00 PM EDT • Technology • androidpolice.com
Ollie Gordon II surpasses 100-yard mark in Week 7

Dolphins RB Ollie Gordon II finishes with 103 rushing yards in Week 7 win

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Oct 25 • 5:55 PM EDT • Sports • sports.yahoo.com
Missile makers see multi-year deals as politics-proof

Executives at the military’s biggest suppliers say the Pentagon’s new multi-year munitions deals are the surest way to navigate an uncertain funding climate.

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Oct 25 • 5:34 PM EDT • Politics • punchbowl.news
Presidential race in Bulgaria heads to runoff due to record low turnout

In a surprisingly strong performance, the candidate of the pro-Western reformist opposition, Andrey Gyurov, will face the incumbent leftist president, Iliana Yotova, setting clear lines of division regarding the country’s future relationships with other nations.

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Oct 25 • 4:39 PM EDT • Politics • pbs.org
Ravens surrender 35 unanswered points in stunning loss to Bengals

Baltimore squandered a 13-0 halftime lead as Joe Burrow threw four touchdown passes and Cincinnati handed the Ravens a 35-13 defeat

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Oct 25 • 4:33 PM EDT • Sports • sports.yahoo.com
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When will Myles Garrett return to the Rams?

Here's the latest on Myles Garrett as he continues recovering from early-season knee surgery.

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Oct 25 • 4:06 PM EDT • Sports • sports.yahoo.com
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Cavs vs. Timberwolves: How to watch, odds, and injury report

The Cavs will welcome the surging Timberwolves to town.

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Oct 25 • 4:01 PM EDT • Sports • sports.yahoo.com
Big Las Vegas show closures mark a transitional time for Strip entertainment

The culture of Las Vegas is inextricably linked to the artists and technicians behind the Strip’s vibrant live entertainment industry, so any time a show closes

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Oct 25 • 3:30 PM EDT • Entertainment • cdcgaming.com
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The Politics of Heaven ~ The Imaginative Conservative

The key to understanding Thomas More’s generous dedication to the real but limited good he could do on earth is, as Frank Mitjans makes clear, that More’s constant contemplation of God was the source of his boundless care for the souls surrounding him. Thomas More’s Vocation, by Frank Mitjans

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Oct 25 • 3:20 PM EDT • Politics • theimaginativeconservative.org
‘I was doing all the right things': What one survivor's diagnosis reveals about breast cancer risk

A new survey and a survivor's experience reveal a gap between what women think puts them at risk and what actually does.

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Oct 25 • 3:20 PM EDT • Health • nbcmiami.com
NZ’s hidden chronic health burden is even bigger than we thought

New research reveals a major gap in how chronic illness is measured, with implications for planning and funding healthcare in New Zealand.

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Oct 25 • 3:10 PM EDT • Health • theconversation.com
MAPPED: The states Trump and top Democrats are targeting before Election Day

With Election Day less than two weeks away, Trump rallied in Florida, Georgia and Michigan as both parties deploy top surrogates to battlegrounds.

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Oct 25 • 2:15 PM EDT • Politics • foxnews.com
Ramaswamy built his political career in NH. It's faltering in Ohio.

Many New Englanders remember Ramaswamy from his mad-dash presidential campaign in New Hampshire. Will his political career survive a tumultuous run for Ohio governor?

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Oct 25 • 2:13 PM EDT • Politics • bostonglobe.com
Navigating D1 pressure: how student-athletes balance their mental health

Mental health affects everyone, including athletes who have a really good way of hiding it. Research shows that mental health issues affect roughly 39-44% of Division I athletes. Behind game day, good game performance, and navigating life in college, D1 athletes are constantly trying to balance high expectations with their own well-being. It’s not...

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Oct 25 • 1:59 PM EDT • Health • nmsuroundup.com
‘You Can See Everything’ surges with $19.5M at box office; ‘Clayface’ takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.

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Oct 25 • 1:17 PM EDT • Entertainment • seattletimes.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KCBS All News 106.9FM and 740AM

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Oct 25 • 1:16 PM EDT • Entertainment • audacy.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KNSS Radio

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Oct 25 • 1:16 PM EDT • Entertainment • audacy.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.

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Oct 25 • 1:16 PM EDT • Entertainment • clickorlando.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KMBZ

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Oct 25 • 1:16 PM EDT • Entertainment • audacy.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.

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Oct 25 • 1:16 PM EDT • Entertainment • news4jax.com
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1

DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday. But the biggest success story in theaters remained A24’s...

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Oct 25 • 1:16 PM EDT • Entertainment • stamfordadvocate.com
'You Can See Everything' Surges With $19.5M at Box Office; 'Clayface' Takes No. 1

NEW YORK (AP) — DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday. But the biggest success story in theaters remained A24’s Elizabeth Holmes documentary “You Can See Everything,” which pulled in $19.5 million in its ...

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Oct 25 • 1:16 PM EDT • Entertainment • usnews.com
Clatsop County health inspections for September

Clatsop County health inspectors recently completed a round of restaurant inspections that yielded overwhelmingly positive results for most local eateries. But one Seaside establishment received a temporary closure after receiving […]

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Oct 25 • 1:10 PM EDT • Health • dailyastorian.com
New Trump housing order targets mortgage and title insurers

A White House plan to pull private mortgage insurance off loans sooner, and to let refinancing borrowers skip the lender's title policy, affects two insurance lines that say they already help keep costs down

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Oct 25 • 1:09 PM EDT • Business • insurancebusinessmag.com
Jaylen Warren surpasses 100-yard mark in Week 7

Steelers RB Jaylen Warren rushes for at least 100 yards for third time this season

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Oct 25 • 12:59 PM EDT • Sports • sports.yahoo.com
Epic CEO Tim Sweeney lambasts “abhorrent” Steam AI Disclosure Policy claiming labels double as “political statement”

Epic Games CEO Tim Sweeney called Steam’s AI disclosure policy abhorrent, arguing that it exposes developers to backlash from anti-AI detractors. Valve has implemented and updated the policy since 2024, which states that AI-generated content, including artwork, text, music, and assets, excluding assistant tools, requires formal disclosure.

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Oct 25 • 12:31 PM EDT • Technology • notebookcheck.net
Cost of employer-sponsored health insurance rises again, survey finds

WASHINGTON — The cost of employer-sponsored health insurance increased again this year, as did the deductibles many people must pay before their plans begin covering most health care expenses, according

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Oct 25 • 11:40 AM EDT • Health • chronicleonline.com
How Nathan Fielder's cringe-comedy career led him to Elizabeth Holmes

Spoiler alert! We're discussing the themes and structure of the Elizabeth Holmes documentary "You Can See Everything" and touching on a surprising aspect of its second half, so turn away if you want to go in completely cold.

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Oct 25 • 11:34 AM EDT • Entertainment • thenewstribune.com
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals

Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.

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Oct 25 • 11:30 AM EDT • Health • fiercebiotech.com
Texas Tech Leads 'Bad' Week 8 for Big 12 Unbeatens

The Red Raiders’ playoff dreams hit a wall in Cincinnati as sloppy play and missed opportunities ended their unbeaten run. The Big 12 race is now more open than ever after surprising finishes elsewhere.

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Oct 25 • 11:28 AM EDT • Sports • sports.yahoo.com
Jennifer Hawks explains why she should be California's State Treasurer

Jennifer Hawks, a candidate for California state treasurer, shared her qualifications and vision for the office in an interview on California Politics 360.

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Oct 25 • 11:25 AM EDT • Politics • kcra.com
Campbell County health and food inspections (10/16/26–10/22/26)

GILLETTE, Wyo. — The Consumer Health Services Division of the Wyoming Department of Agriculture conducts inspections of retail food establishments throughout Wyoming (where there is not a local health department that does inspections) to help ensure safety of Wyoming residents. Campbell County establishments are inspected at least once a year by the WDA. All of […]

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Oct 25 • 11:00 AM EDT • Health • county17.com
Face the Facts: New health insurance helps early childhood educators

Child care is expensive, and keeping qualified workers on the job is part of the challenge. Now, Connecticut is offering a new health insurance subsidy to help early childhood educators lower their monthly premiums. Rep. Kate Farrar (D-West Hartford) explains how it works and why it could make a difference for families. Mike Hydeck: For years, Connecticut has had among…

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Oct 25 • 10:48 AM EDT • Health • nbcconnecticut.com
Aaron Rodgers passes Peyton Manning on all-time touchdowns list

Aaron Rodgers surpasses Peyton Manning in all-time touchdown passes.

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Oct 25 • 10:46 AM EDT • Sports • sports.yahoo.com
😐 Neutral (0%)
9 Cool Camping Features Built Into Oliver Travel Trailers (And 3 You Can Add Yourself)

The utility you can get with an Oliver Travel Trailer these days will surely enhance your next camping trip, but there is even more than meets the eye.

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Oct 25 • 10:30 AM EDT • Technology • slashgear.com
Nuthatches are rude: Ornithological observations from a recliner

I don’t know what age you’re supposed to start sitting in a recliner and looking out the living room window at the bird feeder, but I sure do like doing

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Oct 25 • 10:00 AM EDT • Science • newsminer.com
Manchester United vs Bournemouth: Live updates from Old Trafford

Under-fire Manchester United manager Michael Carrick is under enormous pressure heading into today’s Premier League clash with Bournemouth on the back of a seven-game run without a win.The boss has ...

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Oct 25 • 10:00 AM EDT • Sports • sports.yahoo.com
Explore Health, Oregon’s new health insurance marketplace, is ready for business

This fall, Oregonians who buy health insurance directly instead of getting it through their employer will need to use a new website, the Explore Health marketplace.

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Oct 25 • 9:48 AM EDT • Health • klcc.org
😐 Neutral (17%)
wow
63%
ahah
37%
Explore Health, Oregon’s new health insurance marketplace, is ready for business

This fall, Oregonians who buy health insurance directly instead of getting it through their employer will need to use a new website, the Explore Health marketplace.

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Oct 25 • 9:48 AM EDT • Business • klcc.org
😐 Neutral (17%)
wow
63%
ahah
37%
We moved to an apartment in another country without seeing it in person

We moved to an apartment in the Netherlands without seeing it in person. As Americans, we've encountered lots of surprises and cultural differences.

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Oct 25 • 9:17 AM EDT • Business • businessinsider.com
A last-minute voter guide to all 14 propositions on the California ballot

Californians are voting on 14 ballot measures, including propositions on taxes, voting, healthcare, housing and the environment. It's a lot to take in, but we're here to help.

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Oct 25 • 9:00 AM EDT • Politics • calmatters.org
Pat Surtain II unlikely to play

Pat Surtain has good chance to suit up in Week 8 due to ankle injury

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Oct 25 • 8:48 AM EDT • Sports • sports.yahoo.com
Venomous spiders have a surprising survival secret that has scientists taking notice
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Oct 25 • 8:22 AM EDT • Science • yahoo.com
A doctor traded health insurance for direct primary care, cost-sharing

A doctor explains why he replaced traditional health insurance for his family of four with direct primary care and a medical cost-sharing group.

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Oct 25 • 8:20 AM EDT • Health • businessinsider.com
😐 Neutral (5%)
Not sure who to vote for? Here are the main political parties ahead of Israeli elections

From Netanyahu’s Likud to Eisenkot’s Yashar and Winter’s Amcha Israel, the contenders differ on security, military service, religion and the courts

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Oct 25 • 8:02 AM EDT • Politics • i24news.tv
Deep dive
😐 Neutral (8%)
ahah
56%
wow
44%
Utah Jazz Must Let Darryn Peterson Feel the Pressure

Shielding Utah’s prized rookie from high-stakes moments only stunts his growth. To secure their future, the Jazz must force Darryn Peterson to embrace the game-deciding pressure now.

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Oct 25 • 8:00 AM EDT • Sports • sports.yahoo.com
Texas A&M Defense Folds Again As Alabama Exposes Aggies In Late Collapse

Texas A&M's defense surrendered 311 passing yards and two fourth-quarter touchdowns in a 31-20 loss to Alabama, raising more questions about Mike Elko's Aggies.

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Oct 25 • 8:00 AM EDT • Sports • sports.yahoo.com
A simple liquid can stop cavities without drilling, major study confirms

A simple liquid painted onto teeth in seconds can stop cavities without drilling, injections, or anesthesia, according to a major clinical trial involving young children. The inexpensive treatment could spare thousands of children painful dental procedures and surgery while paving the way for broader FDA-approved use.

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Oct 25 • 8:00 AM EDT • Science • sciencedaily.com
Scientists reveal the hidden danger of missing blood pressure medication

Missing blood pressure medication could mean losing much of its protection against heart attacks and strokes, according to an analysis of more than 91,000 people. Patients who consistently took their medication experienced an 11% reduction in major cardiovascular events, while those who missed too many doses saw little or no measurable benefit.

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Oct 25 • 8:00 AM EDT • Science • sciencedaily.com
Ukraine: Explosive weight soldiers could put on drone surprised maker

Drones' explosive power is limited by gear, like batteries, that they must carry. But soldiers push gear to the limit, surprising even its makers.

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Oct 25 • 7:56 AM EDT • Business • businessinsider.com
US employer health insurance premiums exceed $28,000 for family coverage in 2026

US employer health insurance premiums rose 5% in 2026, exceeding $28,000 for family coverage, while nearly half of working-age adults lack adequate coverage

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Oct 25 • 7:54 AM EDT • Health • beinsure.com
South Texas Health System (@stxhealthsystem)

2 likes, 1 comments - stxhealthsystem on October 25, 2026: "One Last Chance to Think Pink: Breast cancer remains the most common cancer among women after skin cancer, making routine screenings and early detection more important than ever. Mammograms can help identify breast cancer before symptoms appear, when treatment options may be most effective. Last week, South Texas Health System McAllen celebrated breast health and preventive care with a special Mammo Monday event featuring the vibrant sounds of mariachi music at the hospital’s main entrance. The celebration reflected STHS' ongoing commitment to encouraging women to prioritize their health through regular screenings. Now, there’s one final Mammo Monday remaining! Join us at STHS ER Mission on October 26 from 8 a.m. to 5 p.m. for the last breast cancer event of 2026. During the event, attendees can: 🎀 Learn about breast cancer screening options 🎀 Schedule a mammogram appointment 🎀 Receive a complimentary goodie bag while supplies last To help make preventive care more accessible, South Texas Health System is also offering reduced self-pay rates* throughout October: • 2D Mammogram: $100 • 3D Mammogram: $155 • Bone Density Screening: $160 A screening today could make all the difference tomorrow. Make your health a priority and encourage the women you love to do the same. For breast health resources and information on the Think Pink campaign, visit the link in our bio. *If not already a covered benefit of your insurance.".

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Oct 25 • 7:41 AM EDT • Health • instagram.com
Paris Pressure: Saints Must Block Out the Chaos and Finish Their Business Against the Steelers
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Oct 25 • 7:00 AM EDT • Business • sports.yahoo.com
What Californians should know about Prop. 42

The measure could block the billionaire tax — and more.

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Oct 25 • 7:00 AM EDT • Politics • sfexaminer.com
Latino businesses still fearful amid ICE sightings 8 months after Operation Metro Surge

A handful of new Latino eateries have opened on Payne Avenue, as others have slashed hours or remain closed certain weekdays.

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Oct 25 • 6:00 AM EDT • Business • twincities.com
Nevada's Republican governor fights to survive Trump undertow

Joe Lombardo is no MAGA warrior, but his Democratic opponent ties him to the president at every opportunity. Lombardo hopes Nevada voters judge him on his performance, not Trump's.

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Oct 25 • 6:00 AM EDT • Politics • latimes.com
Voters in 2 Democratic strongholds could ban transgender girls from girls school sports

Reliably Democratic Colorado and Washington have ballot measures that would bar transgender girls from some sports competitions

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Oct 25 • 6:00 AM EDT • Politics • latimes.com