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The Best October Prime Day Apple Deals on AirPods, MacBooks, and More
Many Apple’s products are pricier than ever, but we’ve found some decent Prime Day deals on AirTags, AirPods, Apple Watches, and more.
This Weekend in Gators Sports: Tennis Wins Big, Swim and Dive Stays Perfect
Florida swimming and diving and men’s tennis posted strong results on the road over the weekend. Gators men’s tennis returned to Gainesville stamping 15 wins on the weekend at the three-day Bedford Cup hosted by UCF, while Florida men’s and women’s swim and dive remained undefeated against Kentucky 31-0 all time. Men’s Tennis: Doubles Title […]
Hunter Green Named Ray’s Eight, Punting Matchup with Iowa
Washington punter Hunter Green was named one of the “Ray’s Eight” punters of the week by the Ray Guy Award after his 310-yard punting performance at USC. Green punted six times for an average of 51.7 yards with three pinned inside the 20-yard line. Two of his punts were downed at the one-yard line. His …
Columbus Councilmembers say mayor playing politics over damaged rec center
Three Columbus City Councilmembers accused Mayor Andrew Ginther of using a storm-damaged rec center as a “political prop” in a capital budget fight.
Sacramento entertainment spot tops list of best escape room in the United States
Three other California escape rooms also made the list by USA Today.
Wisconsin voters to decide limits on governor’s partial veto power
LA CROSSE, Wis. (WXOW) – Wisconsin voters will see three proposed constitutional amendments on their Nov. 3 ballot, including one dealing with the governor’s partial veto power.
College of Ag Sciences clubs get philanthropy boost from visiting ag company
Three clubs in Penn State’s College of Agricultural Sciences got a recent boost from a new donation from Pivot Bio, a company specializing in products that optimize crop production through specific nitrogen delivery.
Scamacca ‘very happy’ with first Italy goal in three years
Gianluca Scamacca is ‘very happy’ to have scored his first Italy goal in three years, paving the way for the 3-1 win over Turkiye in the Nations League.The Azzurri had quite a sluggish start again...
A health app designed for teachers
A new app is designed to help teachers stay healthy in their day-to-day work. The digital tool is the result of a three-year collaborative project between the Technical University of Munich (TUM) and ...
Joe Burrow Bengals Passing Records Watch: Week 5
Heading into the 2026 season, Joe Burrow has the weight of the world on his shoulders. Can he carry the Bengals back to the playoffs after missing in each of the last three seasons? In 2023, his season was shortened due to a freak wrist injury. That injury was so severe that "experts" on Twitter …
Raiders Coach Doesn’t Regret Taking Points Off Board
The Las Vegas Raiders lost by three points to the Chiefs, but Klint Kubiak doesn't regret taking three off the board.
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.
CSUN in D.C. Internship Expands Student’s Public Health Career Aspirations
For Josiah Morrow, a three-month internship in Washington, D.C., turned the nation’s capital into a classroom — and helped shape his future in healthcare.
Amazon Hires Three Netflix Business Affairs Execs
The streamer has moved to a genre-based model for its business affairs operation.
Pokémon GO Halloween 2026: Part One
Pokémon GO’s Halloween 2026 Part One event runs from October 27 at 10:00 a.m. to November 1 at 10:00 a.m. local time, bringing three new costume Pokémon: Pikachu wearing a hat and capelet, Zubat wearing a top hat, and Sinistea wearing a bow! Expect spooky wild encounters, costume raids, and trick-or-treat surprises that can reward […]
Pat Bryant catches all three targets
Denver Broncos WR Pat Bryant (ankle) caught all three of his targets for 47 yards in Week 4 before exiting with an ankle injury.
Jamie Foxx opens up 3 years after health scare, talks new standup special
Actor, comedian and singer Jamie Foxx opens up to ABC News three years after a health scare nearly ended his life.
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine has been awarded to three scientists whose work led to a tool that uses light to help unravel how the brain works
Spurs employ three-guard lineup during Silver & Black Scrimmage
De'Aaron Fox, Stephon Castle and Dylan Harper played together in what coach Mitch Johnson called "on-the-job training."
Fear is bigger than ever… and Zero Latency VR has the science to prove it
MELBOURNE, Australia — Zero Latency VR, the world’s largest and most innovative immersive VR network, is celebrating a double Halloween anniversary: three years since the launch of Outbreak, …
DHS buys three detention centers in California for $950 million
The GEO Group, a Florida-based private prison corporation, announced Monday that it had sold the detention facilities, including the Adelanto ICE Processing Center, totaling 2,644 Beds.
How former Cyclones performed in Week 4 of the NFL
Ten former Cyclones made appearances in Week 4 of the NFL and played a combined 543 snaps on offense, defense and special teams. Breece Hall – New York Jets Hall did not play against the Chicago Bears due to a quad injury sustained during the Lions game in week three. Jake Hummel – Houston Texans Hummel […]
3 scientists share Nobel Prize in Physiology and Medicine for work in optogenetics
The Nobel Foundation awarded its prize in physiology and medicine Monday to three scientists who researched how nerve cells affect the brain.
Apple event is reportedly happening next week, per Mark Gurman
Apple is expected to launch three new products next week on October 13, and per Mark Gurman, the product unveilings will happen at “an event.”
DeSean Bishop Is the X-Factor Arkansas Must Contain
Arkansas knows exactly where Tennessee’s offensive plan begins. It begins with DeSean Bishop. The Volunteers running back enters Fayetteville after one of the best performances in the country this season. Bishop rushed 34 times for 220 yards and three touchdowns in Tennessee’s 24-14 win over Auburn, turning a game with quarterback uncertainty into a statement …
Three Japanese regional banks consider business integration
The Japanese lenders concerned are Procrea Holdings, Akita Bank, and Bank of Iwate.
Three Preseason Goals For Bulls' First Round Pick Dailyn Swain
To secure his place in Chicago’s future, the versatile rookie must rediscover his offensive aggression, leverage his elite defensive length, and prove he can impact winning beyond scoring.
Scientists reveal what seven days of fasting does to the human body
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.
Ground Zero Blues Club
A Labor of Love for its Three Managers It is no mystery why Ground Zero Blues Club (GZBC) is one of the most famous blues clubs in the country. It is a genuine juke joint where customers are treated to great live music along with genuine hospitality serving up Southern food favorites like barbecue […]
Stanford Professor One Of Three Scientists Awarded The Nobel Prize In Medicine
Stanford professor Karl Deisseroth joins Peter Hegemann and Georg Nagel as winners of the 2026 Nobel Prize in Physiology or Medicine for their work on optogenetics.
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine was awarded Monday to three scientists working on the mechanisms the brain uses to switch on, or off, the activity of individual nerve cells.
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Dan Campbell: I'm not talking about firing Kelvin Sheppard
The Lions defense was unimpressive in the first three weeks of the 2026 season and things didn't get any better in Sunday night's loss to the Panthers.
Three sheriff’s offices sign up for jail mental health hold reimbursements under new Wyoming law
The law allows the health department to pay jails for holding and treating people with mental illnesses while they await a bed at the state hospital.
Nobel medicine prize goes to 3 scientists for research into brain activity
The Nobel Prize in medicine was awarded Monday to three scientists working on the mechanisms the brain uses to switch on, or off, the activity of individual nerve cells.
15 Wallingford restaurants, two stores cited for serious violations during August health inspections
USDA food code violations fall into three categories, including the most serious, which must be fixed within 72 hours.
Nobel prize in medicine 2026 awarded for research on mysteries of brain
Three scientists to share 12m Swedish kronor prize for their work on ‘light-gated ion channels and optogenetics’
Nobel Prize in medicine awarded to three scientists for their work ‘concerning light-gated ion channels and optogenetics’
The 2026 Nobel Prize for physiology or medicine has been awarded to three scientists – Karl Deisseroth, Peter Hegemann and Georg Nagel – for “their discoveries concerning light-gated ion channels and optogenetics.”
ESPN FPI predicts Texas A&M vs. Missouri in Week 6
ESPN FPI only gives Missouri a three percent edge of Texas A&M before Saturday's Week 6 matchup.
Is a ‘political’ email sent with county government resources worth a $5K fine?
Republican County Councilman Nathan Volke is championing three ethics reforms for Anne Arundel County government, with just weeks to go before the election. What’s he hoping to accomplish? How could county government actually change?
3 years after the Oct. 7 attacks, Israel still grapples with its mental health crisis
More than a third of Israelis have shown symptoms of mental health conditions, a report found. Three years after the October 7 attack, the country's health system is still struggling to come to terms with its effects.
RosCept Capsules Introduces Ros Cept Multi-Ingredient Dietary Supplement for Brain Health, Memory and Concentration
RosCept dietary supplement features Magnesium Beta Hydroxybutyrate, Calcium Beta Hydroxybutyrate, and Sodium Beta Hydroxybutyrate in a focused BHB formulation.Wilmington, DE, Oct. 05, 2026 (GLOBE NEWSWIRE) -- RosCept has announced the introduction of RosCept, a multi-ingredient dietary supplement formulated with three mineral beta-hydroxybutyrate (BHB) compounds: Magnesium Beta Hydroxybutyrate, Calcium Beta Hydroxybutyrate, and Sodium Beta Hydroxybutyrate. Official Website: https://roscept.shop/
Monday Red Wings Three Things: Who’s Playing on Tuesday?
Three Things is a quick breakdown of what you need to know today about the Detroit Red Wings. It’s bite-size news you […]
The Nobel Prize Week Is Kicking off in Stockholm With the Medicine Award
STOCKHOLM (AP) — This year's Nobel Prizes will kick off on Monday with the awarding of the medicine prize at the Karolinska Institute in Stockholm. Last year, three scientists won the Nobel Prize in medicine for discoveries about how the immune system knows to attack germs and not our own bodies.
Key to Medicare home health reform is determining program's objective: report
Three possible reforms to Medicare home health are cost-sharing, home health eligibility requirements and optional cash payments, according to a September report from Brookings, a nonpartisan think tank. Which track to choose depends on what the overriding purpose of the program is, the four economist authors say.
Sacramento sisters honor family legacy with dried fruit business
Three sisters in Sacramento have launched Stained Glass Fruit, a company that turns California-grown citrus into dried slices, blending their family’s agricultural history with entrepreneurship.
Former UFC champion closes Cape Coral restaurant
Tito's Cantina is closing its doors after three years in business.
Tito's Cantina in Cape Coral closes after three years in business
Tito's Cantina is closing its doors after three years in business.
DJ Moore leaves Week 4 with another shoulder injury
DJ Moore unable to make it through the first half for the second time in three games in Week 4.
Where These Three Knicks Stand in Contract Extension Negotiations
As the season approaches, the Knicks have three players they may extend soon.
Chourio walk-off single lifts Brewers over Padres
Jackson Chourio smacked a walk-off two-run single to give the Milwaukee Brewers a 4-3 victory over the San Diego Padres on Sunday and a commanding 2-0 lead in their Major League Baseball playoff series.For the second straight day the Brewers rallied from 2-0 down to beat the Padres, who are now in survival mode as the best-of-five National League division series shifts to San Diego for game three on Tuesday.
Business owners offer rewards to those with information on Bissell Street shooting
South Bend Police are still looking for the suspect or suspects in the Bissell Street shooting from two weeks ago that killed three.The community is coming toge
Three Preseason Goals For Chicago Bulls' Rookie Caleb Wilson
As Caleb Wilson faces his first NBA competition, the rookie must translate Summer League dominance into veteran-level shooting, defensive aggression, and a compelling case for the starting lineup.
3 Most Disappointing Cubs Players In 2026
From high-priced free agents to a botched blockbuster trade, these three struggling stars derailed Chicago's championship aspirations and fueled a premature postseason exit against the Padres.
Jakobi Meyers catches three passes in Week 4
Jaguars WR Jakobi Meyers catches three of his four targets in Week 4 win
Digital media health risks warrant global action to protect young people, experts argue
The way digital technologies are currently built and governed creates real risks to health worldwide, alongside genuine benefits, according to a new three-paper series authored by 13 global experts and ...
'Coyote vs. Acme' Earns $100 Million, Proves David Zaslav Wrong
Three years after Warner Bros. shelved "Coyote vs. Acme," the Looney Tunes adaptation is a box office hit.
Chicago police investigating break-ins at multiple businesses in Bronzeville
Chicago police are investigating multiple break-ins after thieves targeted at least three businesses Sunday morning on the city's South Side.
Seahawks lead Chargers 20-6 at halftime
The Chargers had three turnovers in the first half, including two Justin Herbert interceptions.
Jacoby Brissett mistake-prone in Week 4
Arizona Cardinals quarterback Jacoby Brissett completed 21 of 35 passes for 166 yards, two touchdowns and three interceptions in Week 4
White Sox offseason business during the postseason: Arbitration figures, play-by-play future
The last two times the White Sox were in a real postseason — 2008 against the Rays, 2021 against the Astros — they fell behind 2-0 in the the ALDS, and had to scratch out Game 3 victories each time in order to ensure that they wouldn’t participate in the bare minimum of games. Three…
Matthew Golden scores again in Week 4
Green Bay Packers wide receiver Matthew Golden posted three receptions for 21 yards and a touchdown on seven targets in Week 4
Three Takeaways from Packers 17-14 Win vs. Buccaneers
Evan Williams’ late-game heroics saved Green Bay from costly turnovers, securing a gritty victory despite a revamped offense and a devastating wave of defensive injuries.
Three Rivers Corporation promotes Jamie Crockett
Three Rivers Corporation has promoted Jamie Crockett to chief operating officer, placing him in charge of construction and specialty trade operations.
Ben Johnson’s Calm Logic Keeps Overriding the Noise
Most coaches would have just stuck with Case Keenum. After a near-perfect Monday Night Football performance — 247 yards, three total touchdowns, and a 27-7 win over the previously unbeaten Eagles in his first start in more than 1,000 days — riding the hot hand felt like the obvious move. Ben Johnson didn’t make it […] The post Ben Johnson’s Calm Logic Keeps Overriding the Noise appeared first on HEAVY.
Bosnia votes as pro-Russian politician looms large and ethnic tensions simmer
Around 3.4 million voters are choosing the three members of the country's multi-ethnic presidency, lawmakers for the national Parliament and heads of institutions for the country's two entities.
Scientists find a simple size rule that predicts magnetic ground states
Researchers found three distinct magnetic behaviors that appear at specific crystal sizes across several unusual materials.
New England Nation: Keys to the Game Patriots at Bills
New England Nation host Sam Knox and analyst Andy Gresh discusses the three keys to the game for the Patriots to get their first road win of the season in Buffalo.
UCSB AGU Honors: Three Earth Science Researchers Recognized for 2026
Three UC Santa Barbara researchers have been honored by the American Geophysical Union for their outstanding contributions to earth and space science.
Three takeaways from UNC’s home loss to Notre Dame
Maybe there’s more to this team than we previously thought, but is it enough to keep the heat off Bill Belichick?
Three Takeaways From Brewers NLDS Game 1 Win vs. Padres
Milwaukee overcame offensive rust and a controversial officiating call behind clutch home runs and a dominant, scoreless bullpen performance to stifle the Padres in a tense opener.
Braves Minor League Recap: Briggs Opens AFL Season
Briggs McKenzie returned to the mound for the first time in three months to kick off the AFL season.
Novak Djokovic Stuns Alexander Zverev to Reach Beijing Open Semifinals
In one of his best performances this year, Novak Djokovic is once again in the semifinals at the Beijing Open after overcoming World No. 2 Alexander Zverev in a tight three-set match 4-6 6-4 6-4. The Serbian, now 32-0 at the tournament, came from a set down to secure his joint-best win of the season …
PlatinumGames boss hints he wants to expand Bayonetta as Stellar Blade director calls the series "indispensable"
PlatinumGames president Atsushi Inaba says he "strongly wants" to expand Bayonetta, three years after series creator Hideki Kamiya left the studio.
The Roost expands with a third Reno location, introducing three different business models
Explore The Roost's expansion in Reno with its new locations on Robb Drive and in the ROC facility, plus a look back at its Booth Street roots.
3 Questions For Rockets Preseason Opener In Macao
NBA preseason is already underway. Likely MVP candidate Giannis Antetokounmpo has made his unofficial debut for the Miami Heat. Houston Rockets fans will have to wait until Friday, October 9th for their team to play the Dallas Mavericks in Macao. Here are three questions they should look out for when that time comes. 3 Questions …
I tried signature burgers from McDonald's, Wendy's, Burger King
I tried the signature burgers from three fast-food chains: McDonald's, Wendy's, and Burger King.
Exclusive: This Is the Fitbit Edge, Google's Next Fitness Tracker
Exclusive Fitbit Edge images show Google's new screened fitness tracker in three colors, sitting between the Fitbit Air and Pixel Watch 5.
Three Last-Minute Packers vs. Buccaneers Predictions
Green Bay Packers' Jordan Love seeks rhythm against a winless Tampa Bay Buccaneers squad with undrafted rookie Jalon Daniels leading the charge.
NLDS Game 1 notes: Tarik Skubal, Teoscar Hernández, Max Muncy
The Dodgers secured their first postseason game of the year on Saturday, powering three home runs to back a strong start from Tarik Skubal in a 5-3 win over the Atlanta Braves. It was the first time that Skubal was able to pitch at home in a postseason starts, as all of his four playoff […]
Wonka's The Golden Ticket Needs Some Work, But There Are Three Things I Really Enjoyed
Lots of room for improvement, but a few things really worked.
Where to live stream Buccaneers vs Packers for free: NFL, TV channel
The Green Bay Packers and Tampa Bay Buccaneers meet in Week 4 with both teams needing a victory after difficult starts to the season. Green Bay has dropped two of its first three games, while Tampa Bay is trying to…
Fran Brown Delivers Three Important Messages After Syracuse Football Win
The head coach addressed multiple topics following the team's second win of the season, which came against UConn on Saturday.
Jalen Coker Injury Update: Panthers WR’s Week 4 Status Revealed
Jalen Coker has been one of the bright spots for the Carolina Panthers through the first three weeks of the season, but the team may have to make due without him in Week 4. Originally entering the league as an undrafted free agent after the 2023 NFL Draft, the Holy Cross product quickly outplayed his …
Science Snapshots: October 4, 2026
Three new science finds: forest fragmentation alters temperatures, black-hole jets illuminate pre-existing gas, and butterfly wing patterns confuse predators.
Despair over future fuels political anxiety for college students on the cusp of adulthood
EAST LANSING, Mich. (AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University.
Despair over future fuels political anxiety for college students on the cusp of adulthood
EAST LANSING, Mich. (AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University.He will
Despair over future fuels political anxiety for college students on the cusp of adulthood
EAST LANSING, Mich. (AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University.
Despair over future fuels political anxiety for college students on the cusp of adulthood
EAST LANSING, Mich. (AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University.
Despair over future fuels political anxiety for college students on the cusp of adulthood
(AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University. He will graduate in the spring with an economics degree and an interest in dat...
Despair Over Future Fuels Political Anxiety for College Students on the Cusp of Adulthood
EAST LANSING, Mich. (AP) — Frankie Llerandi, 21, has been unable to land a single internship in his three years at Michigan State University. He will graduate in the spring with an economics degree and an interest in data analytics, but true adulthood seems maddeningly far away. Most of his cousins ...
Liverpool will offload struggling forward: Three clubs want January deal
Liverpool strengthened their attack with a couple of new forwards in the summer transfer window. Victor Munoz was onboarded after the Reds triggered the FIFA World Cup winner’s £34m Osasuna release...
Updated SEC football conference standings following Week 5 slate
Only three SEC teams remain undefeated in conference play coming out of Week 5. Here is a look at the latest conference standings.
Three 'Day One' Xbox Game Pass Titles Are Confirmed For The Next Few Days (October 6-8)
With potentially more to come
What do Baldini’s Italy U21 need to qualify for Euros?
Silvio Baldini’s Italy U21 side head into their final Group E fixture knowing one match decides everything.Italy sit second on 24 points, three behind Poland, after Cisse’s late winner in Armenia....
How to get into real estate without a lot of cash: Creative financing
One investor used his paid-off truck to buy property. Three others found creative ways in.
Midwestern State football gets fourth win, passes 2025 season mark
Midwestern State beat Western Oregon to improve to 4-1, besting its three-win total from the entire 2025 season. Here's how they did it.
Jason Bourne author, more celebrities died in SW Florida: Exclusive
Robert Ludlum wrote three Bourne books, including \
Flutter Entertainment PLC (NYSE:FLUT) Stock Has Average Target Price of $155.37
Flutter Entertainment PLC (NYSE:FLUT - Get Free Report) has received an average rating of "Moderate Buy" from the thirty-one ratings firms that are covering the company, MarketBeat Ratings reports. Three investment analysts have rated the stock with a sell recommendation, nine have given a hold reco
Wales vs Denmark – Predicted lineup and team news
Wales will take on Denmark in their fourth UEFA Nations League fixture this Sunday at Cardiff City Stadium, with both sides currently level on three points from three games in the group standings.Wale...