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Lawmakers seek permanent funding for referral hotlines connecting families to mental health care

A bill heard by a Rhode Island Senate panel last week would fold funding for telephone hotlines used by pediatricians and family doctors to connect kids and parents to mental health treatment hotlines into a health department program funded by insurer contributions.

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Apr 6 • 5:50 AM EDT • Health • rhodeislandcurrent.com
Vault: The break from crypto politics is over

It’s been three months since the collapse of the Senate Banking Committee’s effort to advance a landmark crypto market structure bill. Now, with election season right around the corner, the panel is gearing up to try once more.

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Apr 5 • 4:39 PM EDT • Politics • punchbowl.news
This Week in Missouri Politics - April 5, 2026

Scott Faughn is joined by Governor of Missouri Mike Kehoe. On the panel Scott is joined by Reps. Bennie Cook, Mazzie Christensen, Nick Kimble and Missouri Times Editor Jake Kroesen.

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Apr 5 • 12:15 PM EDT • Politics • themissouritimes.com
From Policy to Practice: Shaping the Future of Health Care

Join us for a panel discussion exploring how policy decisions are shaping the future of health care.

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Apr 3 • 6:50 PM EDT • Health • news.ufl.edu
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H.H.S. Takes a First Step Toward Restoring Vaccine Advisory Committee

A federal judge last month questioned the legitimacy of the panel and overturned its recent work. A notice suggests that it may be revived on Robert F. Kennedy Jr.’s terms.

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Apr 3 • 3:17 PM EDT • Health • nytimes.com
New CNN poll shows Democrats up big heading into midterm election season. Can Republicans claw back to avoid a blue wave?
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Apr 3 • 2:04 PM EDT • Politics • cnn.com
Pete Buttigieg Calls For a Politics of ‘Belonging’

A Kennedy School panel discusses polarization and the uncertain future of American democracy.

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Apr 3 • 10:15 AM EDT • Politics • harvardmagazine.com
Big Month for Small Business in Macon-Bibb

Macon-Bibb County’s Office of Small Business Affairs (OSBA) hosted and co-hosted five workshops and panels throughout March, reaching nearly 800 participants across the community. “These workshops and panels are about making sure our small businesses have access to the information, connections, and opportunities they need to grow,” said OSBA Director Charise Stephens. “When we invest […]

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Apr 3 • 10:10 AM EDT • Business • maconbibb.us
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BSAAC hosts LGBTQ+ sports panel to foster community and conversation

On Sunday, the Bowdoin Student-Athlete Advisory Committee (BSAAC) hosted a panel with former men’s lacrosse player Ben Chadwick ’11 to increase awareness of the LGBTQ+ athlete experience. Panelists shared some of the ways they felt supported in their identities as LGBTQ+ student-athletes. Many highlighted their peers, upperclassmen and coaches. “My teammates have always provided a […]

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Apr 2 • 11:28 PM EDT • Sports • bowdoinorient.com
DC Wrap: Bondi fired; Trump orders new tariffs; panel OKs ballroom plans

A look at the day's biggest stories in national politics

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Apr 2 • 5:58 PM EDT • Politics • spectrumlocalnews.com
Federal panel packed with Trump allies approves White House ballroom project

The vote by the National Capital Planning Commission on Thursday marked the final procedural hurdle for President Donald Trump’s plans.

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Apr 2 • 2:28 PM EDT • Politics • washingtonpost.com
‘The business of health care’: Students engage with industry leaders on the future of medicine

The three panelists spoke with nearly 200 students, faculty and community members in Horrmann Library for “The Business of Health Care.”

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Apr 2 • 12:25 PM EDT • Health • wagner.edu
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‘The business of health care’: Students engage with industry leaders on the future of medicine

The three panelists spoke with nearly 200 students, faculty and community members in Horrmann Library for “The Business of Health Care.”

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Apr 2 • 12:25 PM EDT • Business • wagner.edu
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Wave of retirements and politics promise spending panel makeover

The House Appropriations Committee is set to undergo a major shake-up following the midterm elections, especially among its Republicans. With four members retiring, two running for Senate and four others in potentially tight reelection contests, nearly a third of the committee’s Republicans may not return in the next Congress. Democrats are looking at a lower […]

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Apr 2 • 6:06 AM EDT • Politics • rollcall.com
Trump’s White House ballroom project faces panel vote after judge ordered halt

The National Capital Planning Commission had previously delayed the vote after thousands of negative public comments

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Apr 2 • 5:58 AM EDT • Politics • theguardian.com
Global Climate Panel Faces Strife, Potential Funding Crunch

Major reports from the Intergovernmental Panel on Climate Change are still on track, but procedural gridlock and a looming funding shortage hint at future problems.

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Apr 1 • 5:26 PM EDT • Science • insideclimatenews.org
Local high school entrepreneurs pitch business creations at regional competition

Over 20 students from eight different CEO programs pitched their business in front of a panel of judges.

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Apr 1 • 3:57 PM EDT • Business • wgem.com
Supreme Court justices sound skeptical of Trump Administration’s effort to end automatic birthright citizenship
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Apr 1 • 2:04 PM EDT • Politics • cnn.com
Daniel Radcliffe shares why his 20-year-old self 'wouldn't recognize him'

Daniel Radcliffe opened up about his mental health and the joy of fatherhood in a panel following his performance in "Every Brilliant Thing."

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Apr 1 • 9:04 AM EDT • Health • usatoday.com
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Student entrepreneurs compete for $67,500 at annual Business Plan Competition

$67,500 is at stake in the The University of Miami Herbert Business Schools’ annual Business Plan Competition. For 24 years, this experience has been a chance for students to gain real advice and mentorship, and pitch their business idea to a panel of experienced judges. Dr. Susan Amat, an associate professor of professional practice in

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Apr 1 • 8:00 AM EDT • Business • themiamihurricane.com
Wisconsin judicial panel dismisses Democratic attempt to redraw congressional maps

MADISON, Wis. — A three-judge panel in Wisconsin on Tuesday dismissed a lawsuit brought by Democratic voters that sought to redraw the battleground state’s Republican-friendly congressional boundary lines ahead of

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Apr 1 • 1:30 AM EDT • Politics • telegraphherald.com
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Greg Gutfeld: They spent an entire weekend focused on identity politics

Fox News host Greg Gutfeld and the ‘Gutfeld!’ panel discuss Canada’s New Democratic Party handing out ‘equity cards’ to its members.

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Mar 31 • 10:51 PM EDT • Politics • foxnews.com
Members of Congress get the TMZ treatment amid a partial government shutdown
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Mar 31 • 2:00 PM EDT • Politics • cnn.com
Two-Speed Multilateralism: Breaking The Deadlock On Climate And Health

As consensus fails across trade and health sectors, a vital two-speed multilateralism debate in Geneva offers hope for saving the global climate and health agenda.

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Mar 31 • 12:17 PM EDT • Health • healthpolicy-watch.news
Studio Display 2022 vs. Studio Display 2026 Buyer's Guide

Apple updated the Studio Display earlier this month, four years after the original launched. Here's how it compares to the original model. The new model keeps the same $1,599 starting price, 27-inch 5K panel, and overall design, but brings a handful of small internal improvements: a newer chip, upgraded Thunderbolt connectivity, Desk View camera support, and improved bass. The display itself, a 60Hz LCD panel with 600 nits of brightness, is unchanged.

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Mar 31 • 11:45 AM EDT • Technology • macrumors.com
Price Hike or Discount? Nintendo's Changes to Physical and Digital Game Pricing Have Analysts Split, Too

Nintendo games are about to get more expensive. Or less. Depending on whether or not you want a physical copy, and how you read its recent decision to charge different prices for physical and digital games in the U.S. What's really going on? As usual, I have turned to a panel of industry experts to explain.

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Mar 31 • 10:42 AM EDT • Technology • ign.com
This week on The V: Faith, politics and unfinished business

Panel examines faith in campaigns, Tuberville lawsuit, IVF debate and legislative priorities as Alabama's legislative session nears its end.

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Mar 30 • 8:59 AM EDT • Politics • alreporter.com
Apple Reportedly Planning to Launch iMac With OLED Display

Apple is preparing to launch an iMac featuring an OLED panel with higher brightness, according to ZDNet Korea. Apple has apparently requested that Samsung Display, LG Display, and other suppliers produce 24-inch OLED panel samples suitable for a future iMac model using their mass-production facilities. This would be the biggest ever OLED display offered on an Apple device.

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Mar 30 • 7:59 AM EDT • Technology • macrumors.com
New Chattanooga business specializes in gun safety

Ginger Chandler stood at a panel of windows overlooking a vast production floor, where a small team of workers meticulously soldered together electrical components and assembled handguns.

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Mar 28 • 12:00 PM EDT • Business • timesfreepress.com
Solar cells just did the “impossible” with this 130% breakthrough

A new solar breakthrough may overcome a long-standing efficiency barrier. Researchers used a “spin-flip” metal complex to capture and multiply energy from sunlight through singlet fission. The result reached about 130% efficiency, meaning more energy carriers were produced than photons absorbed. This could lead to much more powerful solar panels in the future.

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Mar 28 • 8:00 AM EDT • Science • sciencedaily.com
Bluetti’s Sora 500 solar panel is incredibly powerful for its size

The clear winner for anyone who has limited space to store an extra solar panel.

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Mar 28 • 3:00 AM EDT • Technology • theverge.com
This is a 'huge' political problem for Speaker Johnson, former Biden official warns

Panelists Meghan Hays and Kaylee McGhee White analyze the congressional standoff over DHS funding on ‘America Reports.’

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Mar 27 • 3:58 PM EDT • Politics • foxnews.com
House ethics panel finds Florida Democratic Rep. Cherfilus-McCormick committed 25 violations

The allegations center around Cherfilus-McCormick's receipt of millions of dollars from her family's health care business after Florida made an overpayment of roughly $5 million in disaster relief funds.

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Mar 27 • 10:37 AM EDT • Politics • pbs.org
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House Democrat violated ethics rules, panel finds, putting her seat in jeopardy

A House Ethics Committee panel found Rep. Sheila Cherfilus-McCormick, accused of misusing covid funds, violated ethics rules. She has maintained her innocence.

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Mar 27 • 10:15 AM EDT • Politics • washingtonpost.com
Trump’s new science panel includes 9 tech billionaires—and just one scientist

There's a glaring hole in the president's new science and tech council

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Mar 27 • 10:00 AM EDT • Science • scientificamerican.com
House ethics panel finds Florida congresswoman Cherfilus-McCormick committed 25 violations

The House Ethics Committee has found Democratic congresswoman Sheila Cherfilus-McCormick of Florida committed numerous violations of House rules and ethics standards

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Mar 27 • 9:47 AM EDT • Politics • washingtonpost.com
'That money was earned': Sheila Cherfilus-McCormick counsel pushes back on allegations of siphoning money to campaign

But a bipartisan panel of lawmakers said much of defense at House Ethics trial 'strained credibility.'

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Mar 27 • 4:15 AM EDT • Politics • floridapolitics.com
House Ethics Panel Holds Rare Public Hearing on Democrat’s Conduct

Representative Sheila Cherfilus-McCormick of Florida is charged with stealing $5 million in FEMA money for her campaign.

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Mar 26 • 9:19 PM EDT • Politics • nytimes.com
Cornel West speaks about ‘grim’ moment at panel on Black politics

As a part of a symposium on a new book about how accounts of the civil rights era often romanticize the movement, Cornel West, a prominent academic who ran for president in 2024, spoke at a panel with the author.

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Mar 26 • 8:00 PM EDT • Politics • yaledailynews.com
House Ethics panel declines delay for Sheila Cherfilus-McCormick's Ethics trial

The Miramar Democrat also faces criminal charges and asked Congress hold off on a verdict until her criminal trial.

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Mar 26 • 6:34 PM EDT • Politics • floridapolitics.com
Kennedy, Oz announce new health care advisory committee

The Health and Human Services Department (HHS) and Centers for Medicare and Medicaid Services (CMS) on Thursday announced the formation of a new expert advisory panel that will make recommendations…

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Mar 26 • 6:17 PM EDT • Health • thehill.com
Suffolk town supervisors, on business panel, discuss what lies ahead

Waste management, sewers, housing stock, and an expanded MacArthur airport all were topics of discussion Thursday at the HIA-LI event.

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Mar 26 • 6:06 PM EDT • Business • newsday.com
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HHS convenes health care execs, motivational speaker on panel to modernize health care

The members will advise Kennedy and Oz on how to lower costs and improve care.

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Mar 26 • 3:04 PM EDT • Health • statnews.com
Legislators, business leaders highlight Texas policies driving competition with Wall Street

The panelists at the Dallas event hosted by The Texas Tribune said “Y’all Street” is poised to become the nation's financial capital.

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Mar 26 • 11:42 AM EDT • Business • texastribune.org
Mike Pence To Speak At UChicago’s Institute Of Politics In April

Pence will participate in a student-moderated panel and is expected to speak about the role of the executive branch, populism and more.

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Mar 26 • 8:10 AM EDT • Politics • blockclubchicago.org
Sights from SBJ’s Business of Soccer Day 1

SBJ’s Business of Soccer conference began Wednesday at Mercedes-Benz Stadium in Atlanta, starting with a panel featuring MLS Commissioner Don Garber, FIFA VP Victor Montagliani and U.S. Soccer President Cindy Parlow Cone.

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Mar 26 • 7:00 AM EDT • Business • sportsbusinessjournal.com
Global Chemicals Science Panel Fails to Launch After Chaotic First Meeting - Center for International Environmental Law

Global chemicals science panel stalls after chaotic first meeting in Geneva, exposing political obstruction and delays in tackling toxic pollution.

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Mar 25 • 3:17 PM EDT • Science • ciel.org
Trump staffs science and technology panel with non-scientists

Appointee list is in keeping with the administration's hostility toward science.

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Mar 25 • 12:49 PM EDT • Science • arstechnica.com
Trump taps Mark Zuckerberg, Larry Ellison for science, tech advisory panel

A White House list of 13 appointees includes leaders from Google, Nvidia, Meta, Dell, Oracle, and Andreessen Horowitz.

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Mar 25 • 12:44 PM EDT • Science • fedscoop.com
Trump to name Zuckerberg, Ellison, Huang to tech panel, WSJ reports

U.S. President ​Donald Trump ‌plans to appoint Meta ​Platforms ​CEO Mark Zuckerberg, Oracle ⁠Executive ​Chairman Larry ​Ellison and Nvidia CEO Jensen ​Huang ​to a panel ‌that ⁠weighs in on AI ​policy ​and ⁠other issues, WSJ ​reported ​on ⁠Wednesday

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Mar 25 • 9:12 AM EDT • Science • reuters.com
Exclusive | Trump to Name Mark Zuckerberg, Larry Ellison and Jensen Huang to Tech Panel

The President’s Council of Advisors on Science and Technology is to weigh in on policies affecting the development of AI.

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Mar 25 • 9:00 AM EDT • Politics • wsj.com
Panel debates Trump’s claim that US has won in Iran
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Mar 24 • 10:55 PM EDT • Politics • cnn.com
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Senate Democrats Urge Kennedy to Stop Hindering Key Health Panel

The health secretary has canceled or postponed three meetings of the U.S. Preventive Services Task Force, which shapes health care coverage for Americans.

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Mar 24 • 3:02 PM EDT • Health • nytimes.com
Notre Dame, NBC Sports panel reflects on 20 years of ‘What Would You Fight For?’ storytelling

On Thursday (March 19), the University of Notre Dame hosted an event celebrating 20 years of storytelling through the “What Would You Fight For?” (WWYFF) campaign. Part of the 2025-26 Notre Dame Forum, the panel discussion brought together leaders from the University and NBC Sports to reflect on the impact and evolution of this storytelling platform.

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Mar 24 • 8:00 AM EDT • Sports • news.nd.edu
March fixture list for Arsenal’s 14 internationals

Following five withdrawals, 14 Arsenal players will be involved in the March internationals, so let’s take a look at when they’ll all be in action.Photo by Michael Campanella/Getty ImagesThe vario...

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Mar 24 • 7:35 AM EDT • Sports • sports.yahoo.com
Health Care Access for Women: The Cost of Being Dismissed, March 26

The event will feature a panel and table discussions focused on strategies for women to more effectively advocate for themselves in health care settings.

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Mar 24 • 7:25 AM EDT • Health • today.marquette.edu
The View: Politicians Disappear From ABC Show After Trump FCC Threat

The ABC panel show hasn't had any political guests on since the FCC announced it was investigating it. That changed today as the network fights the feds ahead of the midterms.

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Mar 23 • 4:56 PM EDT • Politics • hollywoodreporter.com
Meet Three Sagehens Playing Spring Sports in 2026 | Pomona College in Claremont, California

The spring sports season offers a smorgasbord of options for Sagehens fans, with teams taking to the diamond, track, pool, field and golf course to test their mettle against Division III athletes from across the country.

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Mar 23 • 3:30 PM EDT • Sports • pomona.edu
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Ruth’s Chris enforces business casual dress code at restaurants

The ‘Nightcap’ panel discusses Ruth’s Chris’ enforcement of a business casual dress code and the viral reaction on social media on 'Fox News @ Night.'

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Mar 23 • 3:23 PM EDT • Business • foxnews.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo

One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening

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Mar 22 • 8:30 AM EDT • Entertainment • pasadenanow.com
GOP Senator says while disenfranchisement is ‘not the intent’ of SAVE America act, ‘we will see that’
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Mar 20 • 1:33 PM EDT • Politics • cnn.com
Rival ‘shadow’ group to RFK, Jr.’s autism science committee meets in D.C.

Autism researchers are working to counter a federal autism advisory panel that has vaccine skeptic members and, they say, a “striking absence of scientific expertise”

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Mar 20 • 12:45 PM EDT • Science • scientificamerican.com
MSU Museum panel teaches about AI, politics and misinformation

Speakers discuss AI and its influence in politics and elections at the MSU Museum as a part of the Department of Political Science's "Blurred Realities" series.

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Mar 20 • 8:00 AM EDT • Politics • statenews.com
Google reverses one of Android’s most annoying UI changes

At least on the Canary channel

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Mar 20 • 2:11 AM EDT • Technology • androidpolice.com
Markiplier to Microdramas: The Ankler x NAB Show’s Future of Entertainment

Share Subscribe Vegas, baby! The Ankler is heading back to NAB Show for a second year in a row — and doubling down on conversations with the smartest people in the industry. From April 18–22, we’re partnering again with the industry’s biggest media and tech gathering to break down the Business of Media and Entertainment as it’s actually evolving: faster, riskier and increasingly driven by new formats, new audiences and new power players. This curated series will bring together top creators, executives and innovators to tackle the forces reshaping the industry — from the AI disruption of Hollywood’s creative ecosystem to the rise of the creator economy, shifting audience behavior and the changing economics of production. We’ll be rolling out more programming in the coming weeks — including top speakers from leading AI studios, prediction markets and beyond — so keep an eye on the Business of Media and Entertainment hub. But first up, we’re announcing two panels about what’s actually working in Hollywood: The Scary-Smart Business of Horror A good scare has become one of the entertainment economy’s most reliable engines. With disciplined budgets, built-in fandoms and global box office upside, horror consistently outperforms. From theatrical releases to streaming-first originals and creator-driven IP, the genre is artistically flexible and financially durable — and one of the last truly communal experiences for Gen Z and Gen Alpha audiences. Join YouTube creator Mark Fischbach, aka Markiplier, whose independent feature Iron Lung earned more than $50 million at the global box office, Atomic Monster president Michael Clear and screenwriter Akela Cooper (M3GAN, Malignant) for a conversation moderated by Like & Subscribe’s Natalie Jarvey about why horror travels so effectively across platforms and borders, how studios and independents are building sustainable genre pipelines and why the next wave of breakout franchises may emerge from unexpected sources. Inside the Microdrama Boom Short-form serialized storytelling is having a major moment. Microdramas, social-native series and creator-led narratives are capturing massive audiences with low-cost, rapid production cycles and direct-to-fan distribution. What was once dismissed as niche or experimental is now attracting major platform investment. Moderated by Jarvey, this panel of microdrama creators and executives — including one of the format’s top stars and producers, Kasey Esser, and Dhar Mann Studios’ head of vertical content, Erin McFarlane — examines how format innovation, fandom dynamics and algorithmic discovery are reshaping the economics of scripted storytelling and what traditional studios can learn from these agile models. For sponsorship opportunities, contact Lynne@theankler.com Share

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Mar 19 • 6:34 PM EDT • Entertainment • theankler.com
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GOP hardliners wavering on support for Bondi subpoena after testy briefing

Conservative hardliners who supported subpoenaing Attorney General Pam Bondi in the House Oversight Committee’s Jeffrey Epstein probe are now indicating that they are open to changing their position after Bondi met with the panel for a briefing that turned contentious with Democrats.

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Mar 19 • 3:43 PM EDT • Politics • cnn.com
How the Iran war is becoming ‘the soundtrack of the midterm election campaign’
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Mar 19 • 1:13 PM EDT • Politics • cnn.com
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'In Good Health': Why Is Colorectal Cancer Affecting Generations Differently?

Cases of colorectal cancer in young people have risen nearly 60 percent since the early 2000s. That’s according to data from the Centers for Disease Control and the National Cancer Institute. And a new study out this month by the American Cancer Society found that colorectal cancer is now the deadliest kind for those younger than 50.But this rise isn’t being felt across all generations in the same way. People born around 1990 are four times more likely to develop rectal cancer than those born around 1950. And for those 65 and older, colorectal cancer rates have actually decreased.So, what’s going on? And what can you do to protect yourself and your gut health? For those answers and more, we turn to a panel of experts.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.

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Mar 19 • 12:46 PM EDT • Health • npr.org
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Science stars at special UChicago, Argonne screening of ‘Project Hail Mary’

Researchers and students marked the new film with a panel discussion, hands-on science demos and a shared love of discovery

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Mar 19 • 8:00 AM EDT • Science • news.uchicago.edu
Trump’s face on a gold coin? His hand-picked panel will decide.

The proposal has already been rejected by members of a separate federal coin committee — and panned by former member Kareem Abdul-Jabbar.

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Mar 19 • 5:00 AM EDT • Politics • washingtonpost.com
Dem Rep. Fires Back at GOP Chair for Accusing Her of ‘B*tching’ at Bondi Briefing
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Mar 18 • 10:06 PM EDT • Politics • cnn.com
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Issues & Ale: It's Just Politics

Join Michigan Public's Political Director Zoe Clark, Senior Capitol Correspondent Rick Pluta, and their FAQ Squad panelists as they give you the facts of the upcoming election cycle!

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Mar 18 • 8:06 PM EDT • Politics • michiganpublic.org
100 Years of Documentary, Funding Cuts, Politics in CPH:DOX Focus

A panel at the Copenhagen doc festival's industry conference also discussed a key reason for the documentary Oscar win for 'Mr. Nobody Against Putin' on Sunday.

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Mar 18 • 1:38 PM EDT • Politics • hollywoodreporter.com
iFixit Tears Down the iPhone 17e, Discovers MagSafe Upgrade Path for iPhone 16e Owners

Repair site iFixit today took apart the iPhone 17e, which is the new low-cost iPhone that Apple launched last Wednesday. The iPhone 17e is almost identical to the iPhone 16e in design, but it does include a MagSafe back panel that supports MagSafe and faster Qi charging than the iPhone 16e. When disassembling the iPhone 17e, iFixit found that the MagSafe panel for the device is the same size as the panel for the 16e, and the two are interchangeable.

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Mar 17 • 3:49 PM EDT • Technology • macrumors.com
iFixit teardown shows iPhone 17e back panel can add MagSafe to iPhone 16e

After opening up the MacBook Neo a few days ago, iFixit is back with a full teardown of the new...

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Mar 17 • 3:45 PM EDT • Technology • 9to5mac.com
High-ranking Trump intel official resigns over war in Iran
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Mar 17 • 2:17 PM EDT • Politics • cnn.com
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WATCH LIVE: Dr. Jay Bhattacharya testifies at NIH oversight hearing before House panel
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Mar 17 • 10:30 AM EDT • Politics • pbs.org
🙂 Positive (35%)
UTC-hosted Regional Science and Engineering Fair highlights STEM talent

Dozens of students from across the Chattanooga region gathered on Monday, March 9, at the University of Tennessee at Chattanooga’s Challenger STEM Learning Center to present their research projects to a panel of judges. The Chattanooga Regional Science and Engineering Fair has existed for 74 years and attracts both middle and high school students to showcase their projects and compete for the chance to advance to the Regeneron International Science and Engineering Fair.

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Mar 17 • 9:07 AM EDT • Science • blog.utc.edu
Science the star at special UChicago, Argonne screening of “Project Hail Mary”

Argonne and UChicago hosted an advanced screening of "Project Hail Mary." The event featured an expert panel on how the film's science resonates with real-world research. UChicago students also hosted hands-on science demos in the theater lobby.

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Mar 17 • 8:00 AM EDT • Science • anl.gov
Federal judge puts RFK Jr.’s new vaccine schedule, advisers on ice

While the judge stayed the Health Secretary's appointments to a key advisory panel, he did not block its meeting this month.

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Mar 16 • 4:51 PM EDT • Health • politico.com
'The View' taps ex-presidential candidate Carly Fiorina as cohost after on-air 'demented' quip

'The View' welcomed former Republican presidential candidate Carly Fiorina as cohost years after ex-panelist Michelle Collins called her face 'demented' on the air.

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Mar 16 • 12:08 PM EDT • Entertainment • ew.com
The Galaxy S26 Ultra has a major display flaw that cheap Android phones solved years ago

Forget the Galaxy S26 Ultra's Privacy Display — I wish Samsung would finally care about PWM dimming and eye comfort features.

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Mar 16 • 5:00 AM EDT • Technology • androidauthority.com
‘It’s not a solvable problem’: Maine’s outgoing hospital lobbyist says there’s no fix for rising health care costs

As Steven Michaud leaves his long-time role with the Maine Hospital Association, he reflected on pivotal events during his tenure.

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Mar 15 • 6:54 PM EDT • Health • pressherald.com
CNN liberal panelist argues billions spent on defense should go to health insurance instead

CNN panelists debate U.S. priorities as Leigh McGowan questions whether spending on the Iran conflict should instead go toward addressing healthcare challenges at home.

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Mar 15 • 5:25 PM EDT • Health • foxnews.com
Outgoing Maine hospital lobbyist says health costs can’t be stopped

Steven Michaud discusses Maine's healthcare affordability challenges, hospital changes, and the need for disease prevention and management.

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Mar 15 • 2:13 PM EDT • Health • bangordailynews.com
Examining MSU's plans in the NIL college sports era

This week we published an exclusive from columnist Graham Couch about MSU's plans for Spartan Ventures to boost athletics.

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Mar 14 • 8:24 PM EDT • Sports • lansingstatejournal.com
Jamie Lee Curtis tears up remembering Nicole Kidman's touching first words to her when they met at the Oscars

Jamie Lee Curtis got choked up at a SXSW panel this weekend recalling Nicole Kidman's touching first words to her when they met at the 2022 Oscars: 'I see who you are.'

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Mar 14 • 6:17 PM EDT • Entertainment • ew.com
‘What a crybaby’ and ‘pouty Pete’: Hegseth critiqued for lashing out at the press over war coverage
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Mar 14 • 12:33 AM EDT • Politics • cnn.com
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N.Y. Senate Republicans to Hochul: Reconvene Climate Action Council over CLCPA

The Climate Action Council is a 22-member panel appointed by the governor and both houses of the Senate and Assembly.

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Mar 13 • 12:45 PM EDT • Politics • spectrumlocalnews.com
OSBA to Host Fifth Annual Women’s History Month Business Panel

On Tuesday, March 17, the Macon-Bibb County Office of Small Business Affairs (OSBA) will host its fifth annual Women’s History Month Business Panel in partnership with the Alumni Chapter of Delta Sigma Theta. The virtual panel will take place from 7:00 p.m. to 8:00 p.m. and is free. Anyone interested can register here. “Over the […]

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Mar 12 • 9:55 PM EDT • Business • maconbibb.us
The Art of Seeing More: a Fearless Science Forum - Morgridge Institute for Research

At "The Art of Seeing More" on March 10, a panel of experts came together for the Morgridge Institute’s Fearless Science Forum series to explore how scientists and artists challenge the limits of human perception.

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Mar 12 • 11:04 AM EDT • Science • morgridge.org
Free workshop in Syracuse to help businesses get MWBE certification

Four panelists will discuss certification opportunities and government contracting for small, local businesses.

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Mar 12 • 10:44 AM EDT • Business • syracuse.com
Michigan Senate panel votes to move the state's primary in 2028

The 10-bill Senate package would eliminate the August election date, beginning in 2028.

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Mar 11 • 11:56 AM EDT • Politics • detroitnews.com
RFK Jr.’s vaccine advisers drop proposal to revisit covid-19 shot

Some members of the CDC’s vaccine advisory panel have publicly questioned the safety and manufacturing of the shots, including raising a debunked theory that DNA contaminants in the vaccines are harmful.

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Mar 11 • 5:00 AM EDT • Health • washingtonpost.com
Gemini in Chrome gets first international expansion

Gemini in Chrome is now coming to Canada, India, and New Zealand, as well as adding support for over 50 languages.

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Mar 10 • 10:30 PM EDT • Technology • 9to5google.com
M5 Max with inconsistent performance and throttling issues - Apple MacBook Pro 14 Review

Notebookcheck Review of the Apple MacBook Pro 14 M5 Max with 128 GB RAM, 8 TB SSD, Nano texture Mini-LED panel, Wi-Fi 7 and PCIe 5.0.

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Mar 10 • 9:57 PM EDT • Technology • notebookcheck.net
Democrats take note as AI, crypto groups splash cash on primaries
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Mar 10 • 1:55 PM EDT • Politics • cnn.com
UConn no longer unanimous No. 1 in women’s basketball coaches poll

In the latest USA TODAY Sports’ women’s basketball coaches poll, one coach on the panel believes that UCLA is the best team in the country.

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Mar 10 • 1:19 PM EDT • Sports • usatoday.com
K&C Sports & Entertainment Law Weekly Roundup

A Florida appellate panel on Friday blocked a lower court's temporary injunction giving an extra year of eligibility for a college basketball player, ruling in a split opinion that the order's...

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Mar 9 • 8:00 PM EDT • Entertainment • jdsupra.com