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NYC Health + Hospitals/Gotham Health Receives Over $1 Million from Queens Borough President Donovan Richards Jr. to Enhance Patient Care Across Queens - NYC Health + Hospitals

Queens, NY — NYC Health + Hospitals/Gotham Health today announced a significant investment of over $1 million from Queens Borough President Donovan

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Mar 24 • 12:20 PM EDT • Health • nychealthandhospitals.org
Paul Renner seeks crackdown on Muslim immigration, Sharia law

'The long-term compatibility of Islam in this country does not exist.'

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Mar 24 • 12:05 PM EDT • Politics • floridapolitics.com
‘Crimson Desert’ Reviews Go From 51% To 80% Positive In Four Days

Crimson Desert reviews have flipped on their heads once players experienced more of the game and the developer dropped a huge patch.

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Mar 24 • 9:33 AM EDT • Technology • forbes.com
12 Life Science Startups Named to SLAS Europe 2026 Innovation Showcase Program

SLAS has named the 12 companies selected to participate in its Innovation AveNEW program at the SLAS Europe 2026 Conference and Exhibition.

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Mar 24 • 9:27 AM EDT • Science • clpmag.com
Gender equality in science: a distant goal; invisible barriers persist

While the number of women in scientific organisations is increasing, the path towards true equality is slowed down by structural barriers and informal processes

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Mar 24 • 9:00 AM EDT • Science • renewablematter.eu
Health care is reshaping the labor market

These days, health care is about more than caring for patients. In the past two years, this service industry has become the economy’s biggest creator of U.S. jobs.

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Mar 24 • 8:13 AM EDT • Health • adpresearch.com
Salamander Migration Has New Citizen Science Component

Each spring, blue-spotted salamanders emerge from their underground burrows at Presque Isle Park in Marquette and venture across the road to lay their eggs. Northern Michigan University students have been involved in conservation, data collection and public education efforts for this annual event, but this year, the general public is invited to play a more active role in salamander migration research. Northern Michigan University Biology Department Head Jill Leonard encourages community members to participate in the Marquette Citizen Science Project.

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Mar 24 • 8:00 AM EDT • Science • news.nmu.edu
UAB scholar receives highest recognition from national small-business and entrepreneurship association

UAB scholar receives highest recognition from national small-business and entrepreneurship association

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Mar 24 • 8:00 AM EDT • Business • uab.edu
March Madness top seeds dominate: Each No. 1 team's path to Sweet 16

Only one perfect 2026 Women's NCAA Tournament bracket remains as of Monday evening following several upsets, but the top seeds have been chalk.

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Mar 24 • 6:06 AM EDT • Sports • usatoday.com
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Opinion | Nothing against California-based Sutter Health, but Allina’s local governance matters

Allina is built on a "model of care that puts patients and families at the center of everything. That is not something that transfers automatically with a transaction. It has to be protected deliberately, by people who understand what it is and why it matters," the writer says.

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Mar 24 • 5:59 AM EDT • Health • startribune.com
The Supreme Court’s conservatives could significantly alter the 2026 election

The Supreme Court on Monday appeared ready to limit mail-in ballots, a move that would reinforce the justices’ pattern of shrinking voter protections and that has, at bottom, favored Republican interests and the Trump administration.

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Mar 24 • 3:00 AM EDT • Politics • cnn.com
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MDMA Therapy in Australia Shows Results for PTSD Patients, but the Cost Is Limiting Access

The country’s experiment with psychedelic medicine has led to positive outcomes, psychiatrists say, but also highlights the limitations of the nascent field.

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Mar 24 • 12:00 AM EDT • Health • nytimes.com
We disagreed on politics. We agreed on wine. That was enough.

At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.

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Mar 23 • 10:54 PM EDT • Politics • dmwineline.substack.com
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Markwayne Mullin confirmed to lead Department of Homeland Security

The Oklahoma Republican faced a glide path to confirmation with the help of two Democratic senators.

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Mar 23 • 8:26 PM EDT • Politics • usatoday.com
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From One Major to Three in Four Years: Connecting Data Science, German and Linguistics at Montclair

In a German language program for local children and on an archive translation project, Isabella Zarate Gonzalez shows how Montclair’s mix of STEM, world languages and community engagement helped her connect her interests into a single path

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Mar 23 • 8:00 PM EDT • Science • montclair.edu
How can you explore careers worldwide? Binghamton student founds club to find out

Binghamton University School of Management student Liam Foley discovers how connecting with diverse cultures creates new pathways for success after founding an international business club.

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Mar 23 • 8:00 PM EDT • Business • binghamton.edu
Insulin pills may soon replace daily injections

For over a century, scientists have chased the dream of insulin pills, but the digestive system kept destroying the drug before it could work—forcing millions of patients to rely on daily injections. Now, researchers at Kumamoto University have developed a clever workaround using a tiny peptide that helps insulin slip through the intestinal wall.

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Mar 23 • 8:00 PM EDT • Science • sciencedaily.com
Utah Sen. John Curtis helps lead push to ban sports betting contracts on prediction markets

Utah Sen. John Curtis and California Sen. Adam Schiff are leading a push to make clear that sports prediction markets are indeed gambling.

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Mar 23 • 7:06 PM EDT • Sports • utahnewsdispatch.com
Bluffton business delivering support to cancer patients

But at one Lowcountry hospital, patients are getting a boost from an unlikely source.

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Mar 23 • 6:59 PM EDT • Business • wsav.com
UFL 2026: Joel Klatt, Curt Menefee Return To Headline FOX Broadcast Team

Joel Klatt and Curt Menefee will once again lead FOX Sports' broadcast coverage for the highly anticipated third season of the UFL.

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Mar 23 • 6:16 PM EDT • Sports • foxsports.com
After patient deaths, Idaho budget committee approves restoring cut Medicaid mental health programs

The Idaho Legislature will consider restoring mental health programs the state cut to comply with the governor’s order for budget cuts.

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Mar 23 • 5:34 PM EDT • Health • idahocapitalsun.com
Anthropic's Claude Can Now Control Your Computer

The developer is boosting Claude's agentic capabilities in an apparent effort to compete with platforms like OpenClaw.

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Mar 23 • 5:00 PM EDT • Technology • cnet.com
Veterinary Science Certificate Program promotes early steps on career path

Rural communities face a growing shortage of veterinary professionals, creating challenges for pet owners and livestock producers alike.

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Mar 23 • 4:59 PM EDT • Science • agrilifetoday.tamu.edu
"Patriotic Kenny" facing health problems, according to his social media
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Mar 23 • 11:40 AM EDT • Health • cbsnews.com
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Epic says it has uncovered rot in patient record sharing. Will HHS act?

A recent Epic lawsuit revealed a company allegedly posed as a provider to access patient records for law firms, prompting a call for increased oversight.

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Mar 23 • 10:48 AM EDT • Health • statnews.com
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New ‘Crimson Desert’ Patch Fixes Storage, Combat, Controls, Bosses, Fast Travel

A new Crimson Desert patch has fixed many of the game's biggest issues not even a week after launch. They really transform the game.

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Mar 23 • 9:11 AM EDT • Technology • forbes.com
Jack Gibbens reflects on ‘bittersweet’ decision to leave Patriots

Gibbens signed a two-year deal with the Cardinals in free agency.

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Mar 23 • 9:00 AM EDT • Sports • sports.yahoo.com
Emmanuel Grégoire, Socialist long involved in local politics, voted new Paris mayor; AP explains

Grégoire won over 50% of the votes, beating out prominent conservative contender Rachida Dati who reached 41% while hard-left contender Sophia Chikirou got about 8%.

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Mar 23 • 8:25 AM EDT • Politics • apnews.com
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A surprising foam discovery could change everyday products

Foams have long baffled scientists because liquid drains from them far sooner than theory predicts. New research shows the reason: the bubbles don’t stay put—they rearrange, opening pathways for liquid to escape. The key factor is the pressure needed to shift bubbles, not just push liquid through them. This insight reshapes how we understand foams and could improve everyday products.

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Mar 23 • 8:00 AM EDT • Science • sciencedaily.com
Inaugural Health Care by Food research award honors excellence in food is medicine science

DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...

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Mar 23 • 8:00 AM EDT • Science • newsroom.heart.org
Every bulb on Govee’s new outdoor string lights can display multicolor effects

Level up your patio.

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Mar 23 • 8:00 AM EDT • Technology • theverge.com
Inaugural Health Care by Food research award honors excellence in food is medicine science

DALLAS, March 23, 2026 — At a time when American dietary patterns are facing renewed attention, the American Heart Association has announced its inaugural Health Care by Food™ Most Impactful Food Is Medicine Research Award, honoring the year’s most...

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Mar 23 • 8:00 AM EDT • Health • newsroom.heart.org
Crimson Desert Steam Reviews Jump to 'Mostly Positive' as Latest Patch Makes Significant Improvements

Crimson Desert Steam reviews are improving, moving up from ‘mixed’ to ‘mostly positive’ on Valve’s platform as developer Pearl Abyss releases game-changing updates.

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Mar 23 • 7:42 AM EDT • Technology • ign.com
PATLABOR the Case Files announced for PS5, PC

Publisher Good Smile Company and developer Chime Corporation have announced 3D action game PATLABOR the Case Files

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Mar 23 • 7:00 AM EDT • Technology • gematsu.com
Cardinal Health Appoints Patricia A. Hemingway Hall as Board Chair

/PRNewswire/ -- Cardinal Health (NYSE: CAH) today announced that its Board of Directors has appointed Patricia A. Hemingway Hall to succeed Gregory B. Kenny as...

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Mar 23 • 6:45 AM EDT • Health • prnewswire.com
Ohio lawmaker proposes election board changes after Delaware County dispute

Dispute at the Delaware County Board of Elections prompted a state lawmaker to propose changes to how county election boards work.

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Mar 23 • 6:03 AM EDT • Politics • dispatch.com
How to beat Gigantamax Pikachu: Best Counters & Guide

Gigantamax Pikachu is a Tier 6 Max Battle in Pokémon GO. It will cost 800 Max Particles to participate in this Max Battle, which will only be consumed if you defeat Pikachu successfully. Gigantamax Pikachu can be shiny from Max Battles. Being an type, it is only weak to type moves. Pikachu can be caught […]

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Mar 23 • 6:02 AM EDT • Technology • pokemongohub.net
New York approves cannabis for anxiety. Science says it may not help

A Lancet Psychiatry study found no evidence cannabinoids treat anxiety, PTSD. In NY, any practitioner can certify a patient for medical cannabis for any condition they deem appropriate.

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Mar 23 • 6:00 AM EDT • Science • timesunion.com
Today's hefty Crimson Desert patch includes "beginning of improvements" to keyboard and mouse controls, plus much more

Pearl Abyss has detailed a rather chunky patch for Crimson Desert, after its launch last week was marred by multiple issues and AI controversies.

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Mar 23 • 5:52 AM EDT • Technology • eurogamer.net
Diabetes, Overlooked and Unchecked, Poses New Risks in Africa

As deaths from diabetes start to rival those from infectious threats like malaria, a new form of the condition linked to malnutrition is surfacing in patients who can afford neither screening nor care.

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Mar 23 • 5:00 AM EDT • Health • nytimes.com
Opinion | Doctors should be paid to keep patients healthy

Value-based care works best when physicians lead, specialists share accountability, and long-term outcomes matter.

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Mar 23 • 3:00 AM EDT • Health • bostonglobe.com
A DNA test ruled him out. He was convicted of murder anyway.

Forensics has its share of high-profile problems. There’s phony “junk science,” like bogus bite-mark and blood spatter analyses that have sent innocent people to jail. And there’s the steady drumbeat of lab scandals, where analysts make up results. But there’s a subtler and more pervasive problem at work in many cases: lab analysts and lawyers who take perfectly legitimate science and twist it. Globe Opinion is exploring these distortions with a series we’re calling “Twisted Science.” And there may be no better place to start than with the case of Terrel Barros.

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Mar 22 • 9:57 PM EDT • Science • bostonglobe.com
Crimson Desert March 23 Update 1.00.03 Released

Pearl Abyss has just released Title Update 1.00.03 for Crimson Desert and shared its full patch notes.

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Mar 22 • 9:48 PM EDT • Technology • dsogaming.com
Man Born with ‘Butterfly Syndrome’ Is Fighting for Change for ‘the Worst Disease You’ve Never Heard of’ (Exclusive)

Ohio resident Shane DiGiovanna, who has the rare disorder epidermolysis bullosa (EB), is advocating for legislation to help cover costly medical bandages for patients with the disease, which is also known as ‘butterfly syndrome.’

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Mar 22 • 6:00 PM EDT • Health • people.com
Why Have Patriots Not Done More To Address Pass Rush?

The New England Patriots had just 35 sacks last season, ranking near the bottom of the league in the regular season.

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Mar 22 • 5:47 PM EDT • Sports • sports.yahoo.com
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Two Offseason Trades Patriots Should Have Made But Didn't

Here are two trades that the New England Patriots should have pursued this offseason but ultimately passed on.

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Mar 22 • 3:07 PM EDT • Sports • sports.yahoo.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Immigration crackdown impact on local Latino-owned businesses

Latino business owners told WRAL News that fear and uncertainty following a nationwide crackdown in immigration enforcement are keeping some families out of public spaces, leaving small businesses struggling to survive. This story was written by Oriana Torre, a senior graduating journalism student at the University of Florida, participating in the CBC-UNC News Media Multiplatform Fellowship.

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Mar 22 • 1:39 PM EDT • Business • wral.com
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The Cincinnati's Favorite Beer 2026 winner is ... (drumroll please)

Our new beer bracket champ had a difficult path to the crown. The final suds match was Vlad (Fretboard) vs. Dunkel (Hofbrauhaus). So, who won!?

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Mar 22 • 10:58 AM EDT • Entertainment • cincinnati.com
We Took Our Three-Year-Old On A Long Haul Flight, And It Was Amazing!

We took our three year old on his first long haul flight in nearly two years. It went so much better than I could have anticipated!

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Mar 22 • 6:50 AM EDT • Technology • onemileatatime.com
Game Preview: Carolina Hurricanes @ Pittsburgh Penguins 3/22/2026

Who: Carolina Hurricanes (44-19-6, 94 points, 1st place Metropolitan Division) @ Pittsburgh Penguins (35-18-16, 86 points, 2nd place Metropolitan Division) When: 3:00 p.m. eastern How to Watch: Locally broadcast on Sportsnet Pittsburgh and FDSN South, streaming on ESPN+ Pens’ Path Ahead: Quality opponents await in the next week; the Pens host Colorado on Tuesday, an Avs team […]

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Mar 22 • 6:00 AM EDT • Sports • sports.yahoo.com
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Andrej Karpathy says he uses an AI agent to control his pool

Andrej Karpathy said an AI agent named Dobby texts him whenever he gets a Fedex package and helps him control his spa.

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Mar 22 • 5:09 AM EDT • Technology • businessinsider.com
The Antidote to Our Growing Crises Must Transcend Politics

Each day, the challenges in our nation pile up. In just recent weeks, there has been the ongoing war in Iran and the Middle East, and ongoing debates about the growing negative impact of the Internet, looming AI challenges, and the Epstein files. The anticipation of divisive, even ugly, midterm elec...

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Mar 22 • 1:40 AM EDT • Politics • thefulcrum.us
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Black Family Wellness Expo returns to Wichita, promotes health awareness for second year

Organizers say more than 40 different vendors participated in the expo.

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Mar 21 • 10:46 PM EDT • Health • kwch.com
Warriors' Stephen Curry set for major checkpoint in injury recovery

According to Steve Kerr, Golden State Warriors star, Stephen Curry will participated in a scrimmage on Sunday, March 22.

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Mar 21 • 8:30 PM EDT • Sports • sports.yahoo.com
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Top 5 states with the highest number of safest hospitals, according to new report

Healthgrades named 438 hospitals across 40 states for its 2026 Patient Safety Excellence Award, with Texas and Florida among the top-performing states.

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Mar 21 • 4:25 PM EDT • Health • foxnews.com
Young scientists shine at Regional Science Olympiad

Budding young scientists from throughout the region participated in the 41st Annual Stanislaus County Regional Science Olympiad on March 14 at Modesto Junior College.

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Mar 21 • 2:20 PM EDT • Science • turlockjournal.com
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Democrats block SAVE America Act amendment to bar transgender athletes in women’s sports

Senate Democrats voted Saturday to defeat a Republican-sponsored amendment to the SAVE America Act that would prohibit transgender athletes from participating in girls’ or women’s sports, an …

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Mar 21 • 1:57 PM EDT • Sports • thehill.com
Wisconsin's Caroline Harvey wins Kazmaier Award as top player

Wisconsin defender Caroline Harvey voted as the winner of the Patty Kazaier Memorial Award for college women's hockey's top player.

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Mar 21 • 12:33 PM EDT • Sports • espn.com
Crimson Desert Hears Your Complaints And Will Fix The Controls

Pearl Abyss says its listening to Crimson Desert players' complaints about the complicated controls and will patch in new options ASAP.

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Mar 21 • 11:37 AM EDT • Technology • kotaku.com
Crimson Desert Dev Promises Patch to Address 'Discomfort Many Players Have Experienced With the Controls,' Apologizes for Awful Keyboard and Mouse Experience

Crimson Desert developer Pearl Abyss has issued a message to players addressing complaints around the game’s controls, which have been widely criticized.

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Mar 21 • 11:30 AM EDT • Technology • ign.com
Crimson Desert Dev to Patch PS5 RPG's 'Uncomfortable' Controls

Apologises for launch day issues

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Mar 21 • 10:30 AM EDT • Technology • pushsquare.com
Doulas can improve health outcomes for women and babies. Insurers are taking notice.

While more Medicaid patients and even some on private plans have gained doula coverage in recent years, United is the first major insurer to begin rolling out the benefit nationwide.

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Mar 21 • 8:00 AM EDT • Health • nbcnews.com
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Microsoft Promises Slew of Windows 11 Changes in Response to "Microslop" Criticisms

With every Windows 11 update seemingly introducing a new bug or somehow breaking some core functionality, it seems as though trust in Microsoft and Windows is at an all-time low, with the recent "Microslop" insult popping up in online tech circles as a sort of culmination of the recent spate of issu...

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Mar 21 • 2:26 AM EDT • Technology • techpowerup.com
Skagit adds dozens of voluntary inpatient beds for mental health and detox

The new 48-bed facility in Sedro-Woolley is a project of the cross-county North Star collaboration

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Mar 20 • 10:10 PM EDT • Health • cascadiadaily.com
Scientists just found a hidden 48-dimensional world in quantum light

A routine quantum optics technique just revealed an extraordinary secret: entangled light can carry incredibly complex topological structures. Researchers found these hidden patterns reach up to 48 dimensions, offering a vast new “alphabet” for encoding quantum information. Unlike previous assumptions, this topology can emerge from a single property of light—orbital angular momentum.

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Mar 20 • 8:00 PM EDT • Science • sciencedaily.com
New AI tool predicts cancer spread with surprising accuracy

Researchers have discovered that cancer spread isn’t random—it follows a kind of biological “program.” By studying colon tumor cells, they identified gene patterns that signal whether a cancer is likely to metastasize. Their AI model, MangroveGS, can predict this risk with about 80% accuracy and even works across multiple cancer types. This could transform how doctors decide who needs aggressive treatment and who doesn’t.

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Mar 20 • 8:00 PM EDT • Science • sciencedaily.com
Press Release - Girls in STEM Program from Keystone Science School

Delivered in an all-girl+ learning environment, Keystone Science School’s Girls in STEM programs encourage participation, collaboration, leadership, and confidence.

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Mar 20 • 7:45 PM EDT • Science • yellowscene.com
Brian Michael Bendis' Powers Animated TV Show in the Works

Bendis and co-creator Michael Avon Oeming are participating in the show's development.

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Mar 20 • 5:21 PM EDT • Entertainment • hollywoodreporter.com
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Exclusive: Dimer Health raises $13.5M for patient discharge

The round gives Dimer approximately three years of runway, though it will begin having initial conversations about its next round soon.

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Mar 20 • 4:32 PM EDT • Health • axios.com
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Prairieville’s Sarah Taylor is scaling a health network for industrial growth

As Ascension Parish’s industrial boom continues to draw contractors and skilled workers to the region, the demand for occupational health services is rising alongside it. NuREADY Health Network is expanding its footprint across the Gulf South to help companies manage workforce testing, injury care and compliance across multiple job sites. Major industrial construction and maintenance […]

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Mar 20 • 3:08 PM EDT • Health • businessreport.com
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What Giants learned from spring training using MLB's ‘interesting' ABS system

The San Francisco Giants learned plenty from a full spring training using MLB's "interesting" ABS system.

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Mar 20 • 1:03 PM EDT • Sports • nbcsportsbayarea.com
Valve releases SteamOS 3.8 preview with Steam Machine support and wider handheld compatibility

Valve SteamOS 3.8 preview is here Valve has released SteamOS 3.8.0 Preview, codenamed "Second Clutch," for the Steam Deck Preview channel. The update adds

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Mar 20 • 8:00 AM EDT • Technology • videocardz.com
Aditya Kaddu

My goal is that my career path always enables me to create real, positive impact on others.

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Mar 20 • 8:00 AM EDT • Business • gsb.stanford.edu
Samsung is bringing AirDrop to Galaxy phones soon

Starting with the Galaxy S26, AirDrop compatibility is coming to Samsung phones, rolling out through software updates. Samsung’s mobile boss Choi Won-joon just confirmed it publicly at a press briefing in Japan. AirDrop has always been the ecosystem glue that people actually feel. People stick with iPhones because their friends all tap a button for […]

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Mar 20 • 7:14 AM EDT • Technology • sammyfans.com
“Loyal Slaves” and Campfire Entertainment in Frank Vizetelly’s Confederate Camp

Frank Vizetelly’s illustration titled “Night Amusements in the Confederate Camp” appeared in the Illustrated London News on January 10, 1863. It was one among a number of wartime scenes that Vizetelly captured for the newspaper. Subscribe Following the war, the illustration appeared in a number of books, including John O. Casler’s Four Years in the Stonewall Brigade (1893) and Campfires of the Confederacy (1898) by Ben La Bree. The scene depicts a Confederate camp at night with an enslaved man, most likely a camp servant, performing a dance around a fire with the music provided by a soldier playing a banjo. Another enslaved man looks on at the right. Vizetelly likely witnessed the scene—one that would have been common throughout the war. It’s a wonderful example of the way in which Confederates—slaveowners and nonslaveowners alike—experienced the presence of slave labor in the army. Vizetelly was deeply sympathetic to the Confederate cause. His depiction of the enslaved man as more than happy to entertain the very people who were fighting to keep him enslaved was precisely the kind of image designed to reassure a British audience that slavery was benign, and by implication, that Britain need not feel morally troubled about recognizing or supporting the Confederacy. Share Just as importantly, the sight of a dancing slave reassured Confederates themselves that the institution of slavery remained secure even after President Lincoln signed the Emancipation Proclamation. I’ve come across this illustration many times before and I plan on using it in my next book project on the role of enslaved labor in the Confederate army during the Gettysburg Campaign, but this is not the reason I am sharing it with you today. It has to do with where I recently found it, which came as a complete surprise and is incredibly revealing. Let’s take a look.

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Mar 20 • 6:43 AM EDT • Entertainment • kevinmlevin.substack.com
Scott Galloway: Cost of his Big Tech protest, paternity leave comments

Scott Galloway wants you to quit Big Tech. First, he had to do his own audit.

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Mar 20 • 5:07 AM EDT • Business • businessinsider.com
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New Spider Mimics ‘The Last of Us’ Zombie Fungus Cordyceps

A newly discovered species of spider in the Ecuadorean Amazon mimics a pathogen, known as a zombie fungus, to protect itself.

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Mar 20 • 5:02 AM EDT • Science • nytimes.com
What doctors wish patients knew about social media’s health impact

From mere FOMO to anxiety and depression, social media platforms can pose harms and benefits. Three physicians discuss how to balance the positive and negative impacts.

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Mar 20 • 3:00 AM EDT • Health • ama-assn.org
Hermès Now Sells $1,250+ MagSafe Chargers Wrapped in Calfskin Leather

Luxury brand Hermès has a new series of MagSafe-compatible chargers for the iPhone and Apple Watch, with prices that are higher than the cost of an iPhone 17 Pro Max. The $1,250 Paddock Solo Charger is a magnetic charger that works with a single device, while the $1,750 Paddock Duo can charge an Apple Watch and iPhone at the same time. The $1,750 Paddock Yoyo is also a dual charger, but it has a USB-C cable that wraps around the charger for travel purposes.

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Mar 19 • 7:03 PM EDT • Technology • macrumors.com
Crimson Desert Day One Update Goes Live in Full on PC, in Part on Console — Check Out the Patch Notes

Crimson Desert has launched across all platforms, and with it comes a day one update that makes some significant improvements to the game, some balance changes, and various fixes. Pearl Abyss recommended players download the patch “for the best experience.” Check out the patch notes.

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Mar 19 • 6:45 PM EDT • Technology • ign.com
Louisville tops South Florida: Highlights and Postgame Videos

Feel free to watch every second of these, or turn the highlight videos off around the 9-minute mark of the second half. Either way, go ahead and soak this up. It’s been a while. Highlights: Pat Kelsey postgame from the bus: Locker room celebration:

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Mar 19 • 6:08 PM EDT • Sports • sports.yahoo.com
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The politics behind the SAVE Act

Commentary: Voting should not depend on navigating bureaucracy, locating old documents, or overcoming financial and logistical barriers.

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Mar 19 • 3:49 PM EDT • Politics • utahnewsdispatch.com
Be counted among the Capital Region’s top private companies

Each year, Business Report ranks the Top 100 Private Companies in the Capital Region — one of our most anticipated and widely read features. It’s the definitive look at the companies driving growth, investment and job creation across our market. If your company is privately held and headquartered in the Capital Region, we want to […]

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Mar 19 • 3:31 PM EDT • Business • businessreport.com
Maxx Crosby Trade Attempt Shows Ravens’ New Aggresive Strategy

The Baltimore Ravens rarely chase blockbuster trades, but their pursuit of Maxx Crosby suggested a different level of urgency. The trade suggested an “all in” motto from a franchise that is known for patience and draft-driven roster building. The deal ultimately fell apart before it could be finalized. Even so, the attempt revealed a willingness […] The post Maxx Crosby Trade Attempt Shows Ravens’ New Aggresive Strategy appeared first on The Lead.

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Mar 19 • 1:58 PM EDT • Sports • sports.yahoo.com
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Tariffs and Mitigating Actions: Focus on the Business Law Section Report with Participation of the International Section and Real Property Law Section - New York State Bar Association

The Business Law Section presents this report on tariff policy developments since February 2025. IEEPA-based tariffs have imposed rates of 10% to 50% on nearly all trading partners. Litigants have challenged the asserted authority for these tariffs in federal court, with an appellate decision invalidating that authority now on appeal before the U.S. Supreme Court.

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Mar 19 • 11:17 AM EDT • Business • nysba.org
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War is only the starkest way that politics is disrupting tourism

Geopolitics disrupts global tourism as wars, visa restrictions and political tensions reshape travel patterns, affecting destinations from the Caribbean to Asia.

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Mar 19 • 9:50 AM EDT • Politics • economist.com
WATCH LIVE: Gabbard, Patel, Ratcliffe testify in House hearing on national security threats
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Mar 19 • 8:15 AM EDT • Politics • pbs.org
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German Health Minister Nina Warken and WHO Hub in Berlin highlight 2025 achievements

Germany’s Federal Minister of Health, Nina Warken, visited the WHO Hub for Pandemic and Epidemic Intelligence in Berlin today to review progress and launch its 2025 Annual Report. The report highlights advances in using artificial intelligence, data science and pathogen genomics to strengthen global preparedness for future pandemics.In 2025, the WHO Hub in Berlin worked with more than 160 Member States and over 190 partners to help countries and organizations develop new systems and tools to detect and understand new public health threats as quickly as possible, whenever and wherever they occur.BMG to confirm whether they wish to contribute a quote. “Detecting outbreaks early is one of the most effective ways to save lives and prevent epidemics from becoming global crises,” said Federal Minister of Health Nina Warken. “Germany is proud to host and support the WHO Hub for Pandemic and Epidemic Intelligence. Its work strengthens our safety at home and helps protect people worldwide.”Artificial intelligence is increasingly transforming the detection of outbreaks. In 2025, the Hub launched an upgraded version of the Epidemic Intelligence from Open Sources (EIOS) system, which uses enhanced AI functions to scan global online information in real time and help experts quickly identify unusual health events. The system is now used by 120 countries.To better anticipate health threats, countries need information beyond traditional health data. The Hub supports countries in implementing Collaborative Surveillance, which integrates data on climate, animals, travel, and population movement to provide a more comprehensive and real-time understanding of health threats.The Hub also expanded global access to pathogen genomics, which helps scientists detect new pathogens, such as viruses and bacteria, understand how they spread and how dangerous they may become. Through the International Pathogen Surveillance Network (IPSN), the WHO Hub in Berlin worked with 309 partners in 101 countries to expand access to these technologies.“We are in a new era of global health threats, and we need new tools to face tomorrow’s challenges,” said Dr Chikwe Ihekweazu, Executive Director of the WHO Health Emergencies Programme. “The WHO Hub in Berlin helps countries use data and technology more effectively so they can identify risks earlier and respond faster. No country can address these threats alone. Strong cooperation remains our best defence.”“Berlin offers an ideal environment for our work. We collaborate closely with world-leading institutions such as the Robert Koch Institute and the Charité Center for Global Health,” said Dr Oliver Morgan, Head of the WHO Hub for Pandemic and Epidemic Intelligence. “Germany has supported the WHO Hub since its establishment, and we are pleased to welcome Federal Minister Nina Warken to the Hub today. This strong partnership helps us advance innovation in pandemic and epidemic intelligence and better support countries to prepare for future health threats.”The Hub is expanding the use of advanced analytics and mathematical modelling to forecast how outbreaks may develop and to assess which response measures are most effective. Through its Collaboratory, the Hub connects modelers and analysts with governments to ensure their work addresses real public health needs. In 2025, the community grew to 1300 members from 50 countries and 200 institutions. An AI-powered pandemic simulator, currently in the prototyping phase, will help decision-makers compare outbreak scenarios and help identify effective disease control measures.

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Mar 19 • 8:00 AM EDT • Health • who.int
Interventional radiology breakthrough in portal vein thrombosis treatment

A UCLA Health interventional radiologist has successfully performed the first pediatric percutaneous spleno-renal shunt procedure to treat severe portal hypertension in a 6-year-old patient. This minimally invasive procedure aims to relieve complications associated with portal vein thrombosis, showing promising long-term outcomes.

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Mar 19 • 8:00 AM EDT • Health • uclahealth.org
Trump may push Japan for help with Iran war in White House meeting

U.S. allies such as Germany, Italy and Spain have ruled out participating in any Gulf mission.

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Mar 19 • 7:36 AM EDT • Politics • detroitnews.com
Will the Allina-Sutter Health deal drive up the cost of health care in Minnesota?

Minneapolis-based health system says bigger will be better for patients, but economists worry about the consumer cost.

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Mar 19 • 7:00 AM EDT • Health • startribune.com
Should R.I. regulate private equity in health care after crisis at safety-net hospitals?

On the R.I. Report podcast, a Salve Regina University expert talks about what Massachusetts, Maine, and Oregon have done to control private equity and protect patients.

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Mar 19 • 5:55 AM EDT • Health • bostonglobe.com
Pittsburgh premiere of 'Eureka Day' stage comedy tackles vaccine politics

Jonathan Spector’s play “Eureka Day,” making its Pittsburgh premiere at City Theatre, depicts what happens to even a group of people who might seem highly compatible when a single hot issue scorches the earth between them.

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Mar 19 • 5:30 AM EDT • Politics • wesa.fm
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Forum on harnessing Artificial Intelligence for health equity

Register to this forumOver the past decade, artificial intelligence (AI) has significantly evolved in complexity, performance, and utility. Its integration across a wide range of industrial sectors has accelerated, with healthcare emerging as one of the most transformative sectors. In this sector, AI has enabled high-impact applications – from enhancing the speed and accuracy of disease diagnosis and supporting clinical decision-making, to strengthening public health initiatives such as disease surveillance and workforce optimization. Moreover, AI holds immense potential to empower individuals, enabling them to take greater control of their personal health and well-being. Yet the central question remains: Who benefits, who is at risk, and do these innovations close or widen health inequities? While the potential of AI-enabled applications is substantial, many countries have approached their adoption with caution. This hesitancy stems from concerns about risks and benefits, including model bias, data breaches, privacy violations, and the erosion of professional skills due to over-reliance on AI. Additional barriers include inadequate data infrastructure and a lack of robust evidence on the most effective forms and interfaces of AI to enhance service delivery and system performance. Moreover, the rapid rise of Generative AI has introduced a heightened urgency for the development of comprehensive governance and ethical frameworks. The Asian Development Bank (ADB) Health Practice Team and Digital Sector, in collaboration with the World Health Organization (WHO) Regional Office for the Western Pacific, are convening the Forum on Harnessing AI for Health Equity on 25–26 March at ADB Headquarters. Senior health officials from 16 developing member countries (DMCs), alongside leading researchers, innovators, and policymakers from across Asia and the Pacific, will engage in discussions on how AI can be governed, financed, and scaled to deliver healthier lives for all. The forum is funded through the High-Level Technology Fund with support from the Government of Japan. Objectives The two-day forum aims to:Identify high-impact, evidence-based health AI use cases suitable for resource-constrained settings and map out a pipeline for potential supportIntroduce and validate the WHO's policy guidance on minimum necessary ecosystem for countries and institutions to self-assess readiness for AI adoptionObtain initial commitment from participating stakeholders to join a pilot regional initiative focused on data/model sharing for a priority health challengeEndorse a prioritized set of actionable policy recommendations focusing on governance, regulation, and sustainable financing necessary to scale high-impact health AI use cases in resource-constrained settings Target participants The forum will convene participants from 16 ADB DMCs including Bangladesh, Bhutan, Cambodia, Cook Islands, Fiji, Indonesia, Lao People's Democratic Republic, Mongolia, Nepal, Palau, Papua New Guinea, Philippines, Sri Lanka, Thailand, Uzbekistan, and Viet Nam. In addition, health system leaders and practitioners, private sector technologists, academic experts, representatives from civil society organizations, development partners, and philanthropic institutions engaged in AI for Health from Australia, the People’s Republic of China, Japan, Malaysia, New Zealand, Singapore, and the Republic of Korea will also be invited. SessionsDay 1 (25 March)Session 1: AI Use Cases for the Care Continuum: Improving Access and QualitySession 2: Adopting a risk-based approach for AI use case prioritizationSession 3: Establishing the Minimum Ecosystem for Implementation Risk ManagementSession 4: Future-Ready Health Workforce: Building Competency for Human-AI CollaborationDay 2 (26 March)Session 5: The Political Economy of AI in Health: Understanding Stakeholder Interests and their Impact on EquitySession 6: AI and Health Financing: Supporting Fair Coverage and ProtectionSession 7: AI Regulation and Oversight: Pathways for Different RealitiesSession 8: The Way Forward – Building Alliances and Regional Partnership How to registerThe forum will be held in a hybrid format. In-person attendance is by invitation only, while livestreaming of the forum will be available to the public. To register, please complete this form on or before 24 March 2026.Event organizers / partnersAsian Development Bank (ADB)WHO Regional Office for the Western Pacific High-Level Technology Fund (HLTF)ContactAkihito WatabeHealth Specialist, SD3-HSDawatabe@adb.org Jae Kyoun KimHealth Specialist, SD3-HSDjkkim@adb.org

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Mar 19 • 1:13 AM EDT • Health • who.int
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