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Servier completes the acquisition of Edgewise Therapeutics' Muscular Dystrophy Business
/PRNewswire/ -- Servier, an independent international pharmaceutical group governed by a foundation, today announced that it has completed the acquisition of...
Prednisone may impair bone health in children with Duchenne muscular dystrophy
In a new study published in Scientific Reports, an international and multidisciplinary research team including Binghamton University researchers identified a set of blood proteins that may explain why the corticosteroid prednisone, although beneficial in treating Duchenne muscular dystrophy (DMD), can interfere with childhood growth and bone health.
Servier to Acquire Edgewise Therapeutics' Muscular Dystrophy Business
/PRNewswire/ -- Servier, an independent international pharmaceutical group governed by a foundation, today announced that it has entered into an agreement to...
Tirzepatide Boosts Metabolic Health in Partial Lipodystrophy
Tirzepatide significantly improves metabolic health and reduces insulin dependence in patients with partial lipodystrophy.
Efzimfotase alfa demonstrated improvements in bone health in treatment-naïve pediatric patients with hypophosphatasia achieving median difference of 1.67 vs placebo in RGI-C Score at week 25 in MULBERRY Phase III trial
Positive results from the MULBERRY Phase III trial showed that efzimfotase alfa (ALXN1850), an investigational enzyme replacement therapy, demonstrated a statistically significant and clinically meaningful improvement in bone health in children (2 to
Servier to buy Edgewise's muscular dystrophy business for $2.65bn
Servier has signed an agreement to acquire Edgewise Therapeutics’ muscular dystrophy business in a deal valued at up to $2.65bn.
Scientists uncover how muscles preserve their repair cells
Researchers discovered an unexpected role for TRF2 in preserving muscle stem cell identity, offering new insights into muscle regeneration and muscular dystrophy.
New obesity discovery rewrites decades of fat science
Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced. Even more surprising, people and mice missing this protein don’t become obese as expected; instead, they lose fat tissue in a dangerous condition called lipodystrophy.
TheBodyPro: HIV-associated lipodystrophy persists as a health concern in the modern ART era
Lipodystrophy remains a real and present issue among HIV patients today — both as a legacy matter and as a still-emerging concern with a significant impact.