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An Italian Day in Philadelphia: Science, Medicine and a Transatlantic Bridge
PHILADELPHIA, Oct. 19. A single human body carries trillions of bacteria. In women, those microbes rise and fall with estrogen, and they help decide who delivers a baby early, who gets an infection that will not clear, and who does not.
Brain fog and the FemTech market | Investors Lab
A slew of pharma heavyweights (Eli Lilly, Bayer, Pfizer, Merck, Viatris, Novo Nordisk, Roche and AbbVie) have a piece of the pie in estrogen replacement.
Calcium-rich whey permeate improves bone health in postmenopausal women, study finds
AFI AFI COPENHAGEN, Denmark, Oct. 20, 2026 (GLOBE NEWSWIRE) -- Twice-daily supplementation with calcium-rich whey permeate supports the maintenance of bone mineral density in postmenopausal women, according to a 12-month clinical study.[1] Declining oestrogen levels during menopause can accelerate bone loss and reduce bone mineral density, increasing osteoporosis risk. The findings come from the RENEW project, a research collaboration investigating how calcium-rich permeate from whey production
Many Women Are Still Struggling to Fill Estrogen Patch Prescriptions. What to Do If You Can’t Get Yours
As demand for menopause treatment increases, estrogen patches are hard to find at pharmacies. Here’s what to do if you can’t refill your prescription.
Pregnancy 'Brain Fog' Is Real, Study Finds, And Scientists May Know Why
Researchers found that sustained high oestrogen levels disrupted a brain pathway linked to memory in mice, while a study of 70 women found that higher oestrogen levels were associated with poorer performance on some memory tests during late pregnancy.
Menopause and estrogen patches dominated DC conversations. Now what?
Menopause took center stage in Washington, DC, with meetings about testosterone, estrogen patches, and how to improve women's health care.
Congress set to discuss this once taboo topic in women's health
Congress will talk about vaginal estrogen and hot flashes at its first-ever hearing on menopause Wednesday, Sept. 16.
Bone Health Without the Hype
I am at the Australasian Menopause Society meeting and we had a fantastic lecture on Bone Health on Day 2, called, “Everything you need to know about bones - except the boring bits!” Spoiler alert, there were no boring bits. The lecture was given by Dr. Amanda Beech, who is a senior staff specialist in Obstetric Medicine and Endocrinology at the Royal Hospital for Women, where she is director of the Bone Density Unit. I want to summarize my top 10 take-aways for you. Share Osteoporosis is a disease of low bone mass, disruption of bone microarchitecture, and fragility of the skeleton. It is a silent disease…until someone develops a fracture. The diagnosis of osteoporosis is based on either fragility/minimal trauma fractures or a T-score of less than -2.5 on a DXA (Dual-Energy X-ray Absorptiometry) or bone scan. It is important to recognize that about 50% of minimal trauma fractures occur when women have low bone mass (often referred to as osteopenia), but not osteoporosis. This tells us that bone strength is more complicated than a number on a DXA report. I am going to add a little here that wasn’t in the talk (one can only include so much in 25 minutes), as many women might read the above paragraph and think, “Shouldn’t we be treating everyone with low bone mass if this is when 50% of the fractures occur?” Many fractures happen for women with low bone mass because there are so many women with low bone mass –it is a statement about the population on a whole, not about the fracture risk of low bone mass. For you as an individual, bone density is only one component of fracture risk and many women with lower bone mass will not have a significantly elevated fracture risk. This is why individualized risk assessment matters. Subscribe We build bone in our teens and twenties, and by the time we are about thirty we have reached peak bone mass. This is why, when we discuss risk factors for osteoporosis, it is important to consider factors that might have affected us in our teens and twenties when we were actively building bone, such as nutritional restriction/energy imbalance. It is important to ask women about a history of eating disorders, and for those with such a history, getting a bone scan in perimenopause or at age 50 is likely warranted. (This image below isn’t from the talk, but is similar to one that was). Bone mass is relatively stable until about two years before the final menstrual period, and perimenopause marks a time of rapid bone loss for women. Using urinary markers of bone loss we know that the time of significantly accelerated bone loss starts about 1 year before the final period and ends about 2 years after the final period. The Study of Women’s Health Across the Nation (SWAN) shows that over the menopause transition women lose an average of 10.6% of the bone at their lumbar spine and 9.1% at the femoral neck While this wasn’t covered in the lecture, I want to add that the rapid bone loss during perimenopause is clearly related to more than estradiol, because during this time estradiol levels can be erratic and not uniformly low. Bone loss during perimenopause is likely a multi-hormone event. For example, rising FSH (follicle stimulating hormone) tracks with bone loss better than estradiol, and there is evidence that FSH may act directly on bone. While decreased estrogen matters, there is clearly more going on. FSH and bone is an active area of research. Subscribe Screening for osteoporosis was recommended fairly broadly before age 65, and was taken from the “Practitioner’s Toolkit for Managing Menopause,” from Monash University. Here is a screenshot from the toolkit that was used as a slide: I am going to add a little bit more about body weight here for clarification. Low body mass (typically 152.1 lb): 0 points (risk neutral) 60–69 kg (132.3–152.1 lb): 3 points (adds some risk)
U.S. Department of Health Announces Key Leadership Changes at FDA
Sept 8 (Reuters) - The U.S. Department of Health and Human Services on Tuesday named four senior leaders at the U.S. Food and Drug Administration, including the heads of its drug center and vaccines and biologics unit. (Reporting by Christy Santhosh in Bengaluru; Editing by Tasim ...
In 2001, scientists began adding 5 to 6 nanograms per litre of synthetic estrogen to an Ontario lake; after 2 seasons its minnow population collapsed
A tiny concentration of a synthetic hormone was enough to trigger a dramatic ecological change in a remote Ontario lake. In 2001, scientists began adding the synthetic estrogen 17α-ethynylestradiol (EE2) to Lake 260 in northwestern Ontario, maintaining concentrations of about 5 to 6 nanograms per litre.
Estrogen’s Role in Female Athlete Muscle Health
Brandon Pfeifer and Dr. Robert Hyldahl explore how estrogen affects muscle recovery and growth in female athletes.
Bone Health During Breast Cancer
Some breast cancer treatments lower estrogen and can weaken bones. Find out why and how to keep your bones strong during treatment and beyond.
Women can't get estrogen patches. Here's what the FDA is doing to help.
Estrogen patches, one of the most popular menopause treatments, have been in short supply this year. Now the FDA is working to fix it.
Estrogen patch shortages are getting worse and could last for years
A spokesperson for the FDA said the agency is coordinating with companies to support efforts to boost the supply of patches for women with menopause symptoms.
Can a new heart health metric identify fracture risk in postmenopausal women? Study finds link
Postmenopausal women face a high risk of bone fractures. Due to declines in estrogen levels, which can lead to an increased risk of osteoporosis, even a low-impact fall can result in a serious hip, back, ...
Do Colds Impact Men And Women Differently? Science Says Yes, Here's Why
While the "man flu" stereotype paints men to be dramatic sufferers, studies show women often have severe and prolonged symptoms like intense fatigue and inflammation due to oestrogen-fueled immune overdrive.