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Results for " surgical " 119 found 🔀 AI-powered Shuffle

Kings’ Murray ‘Happy’ To Start the Season Healthy

After enduring a surgical recovery and a career-low 23 games last year, Sacramento’s vital X-factor returns to the hardwood aiming to reclaim his elite two-way form.

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Oct 21 • 2:36 PM EDT • Sports • sports.yahoo.com
UW Health East Madison Hospital expands surgical capacity

MADISON, Wis. — UW Health East Madison Hospital is expanding its facilities to meet growing health care demand in Dane County.

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Oct 20 • 7:21 PM EDT • Health • channel3000.com
UW Health's East Madison Hospital unveils $140 million expansion

Additions include six new operating rooms, bringing the hospital’s total to 20 operating rooms. There will also be increased surgical prep and recovery bay capacity — increasing from 23 to 60. Inpatient beds are increasing from 84 to 98.

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Oct 20 • 12:16 PM EDT • Health • spectrumnews1.com
Essentia Health hosting joint-replacement seminar in Fargo

Essentia Health on Tuesday, Oct. 27, will host a seminar in Fargo highlighting available surgical options for joint replacement.

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Oct 20 • 11:39 AM EDT • Health • essentiahealth.org
UW Health’s East Madison Hospital expands amid patient demand

The $140 million project expands inpatient and surgical capacity as officials say increases in patient demand continue to grow.

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Oct 20 • 6:10 AM EDT • Health • captimes.com
What causes sleep paralysis; health indicators of Alzheimer's diagnosis; sober October; plus other stories with Vanderbilt Health sources

(iStock) Food and Wine interviewed Peter Martin, MD, Professor of Psychiatry and Behavioral Sciences, for a story about sober October. William Schaffner, MD, Professor of Preventive Medicine, was quoted in CNN International’s Connect the World with Becky Anderson and NewsNation Morning in America for stories about the reported plague situation in Russia, after a laboratory worker at an institute in Siberia dedicated to studying the plague and other infectious diseases died of a mysterious illness. Prevention interviewed James McGuirk, MD, Assistant Professor, Division of Sleep Medicine, for a story about what causes sleep paralysis. Modern Healthcare interviewed Daniel Fabbri, PhD, Associate Professor of Biomedical Informatics and Computer Science, for a story about how health systems are managing AI token costs. WNKY interviewed Ziv Beckerman, MD, Associate Chief of Pediatric Cardiac Surgery, Surgical Director of Pediatric Heart Transplantation in the Golisano Pediatric Heart Institute at Monroe Carell Jr. Children’s Hospital at Vanderbilt about rapid recovery with extended ultra oxygenated preservation (REUP) that is a new form of preservation for heart organs. Ray Romano, PhD, MPH, MSN, Nurse Practitioner, Vanderbilt Memory & Alzheimer’s Center, was quoted Prevention about research that found other health issues may be an early indicator of Alzheimer’s.

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Oct 16 • 4:49 PM EDT • Health • news.vumc.org
Can AI solve our mental health access problem?

Last week I asked you what worries you most about AI in health. It was close, but your top answer was “AI giving bad health advice.” Last week’s poll results: You’re in good company. This concern was top of mind at a conference I joined at Stanford last week, where researchers, clinicians, and people who build AI systems spent a day debating trust and safety in health AI. Stepping back, I’m also hearing your emerging concerns about AI’s impact on our well-being generally. I see this as a matter of public health, and we’ll take it in pieces as we learn together. Today we’ll focus on AI chatbots used for therapy for mental health. Early this month, Governor Newsom vetoed Senate Bill 903, California’s most ambitious attempt to regulate AI use for mental health. It’s at the center of active debate, and raises the questions patients, family members, citizens, and voters will face as AI moves deeper into health care. Let’s work through it. What is “AI-based therapy”? It’s really two things: purpose-built mental health apps designed to deliver structured support, and general chatbots like ChatGPT, Claude, and Gemini that people increasingly use for emotional support—even if they weren’t built for it. Spoiler alert: I don’t know whether the shift toward AI therapy is good or bad. The evidence isn’t there yet. But I do know it’s already happening, and I have some ideas about how we can roll it out with safety in mind. The therapy dilemma, in a nutshell Mental health challenges are common, and strain health and well-being across populations. Therapy (interactive dialogue with a trained, empathetic practitioner) helps many people heal. The demand for licensed therapists far exceeds the supply in California, and AI-based therapy can narrow that gap. AI-based therapy remains novel, unproven, and not well tested. Right off the bat, we can see we’re dealing with trade-offs here. Since the main driver of demand for therapy from a robot is lack of access to therapy from a human, we’ll start there. It’s too hard to find and afford a human therapist California is short roughly 55,000 licensed, non-prescribing therapists and counselors, about 40% of what we need. Psychiatrists, who rely on talk therapy as a complement to prescribed medications, are even more scarce. Eight counties have none, and density ranges from 1.7 per 100,000 residents in San Benito County, to 68.1 in Marin County. My wife is a psychiatrist in Marin, and even here access is tight. If it’s hard in the best-supplied county, imagine rural Sierra County, or the San Joaquin Valley. In 2024, more than half of Californians who tried to make a mental health appointment struggled to find a provider who took their insurance, compared with 14% for physical health care. When Senate staff posed as “secret shopper” patients and called 120 mental health providers in Medicare Advantage networks, they landed an appointment less than once for every five tries. Insurers pay behavioral health clinicians about 22% less than medical and surgical clinicians for comparable office visits. On top of that, billing denials and prior authorizations hit hardest at the solo and small practices common in mental health. Psychiatrists opt out of Medicare at the highest rate of any specialty. In many places, a cash practice for therapy fills quickly with patients paying $250 or more an hour, with no insurance paperwork at all. Families who can pay cash find providers more easily. Those who rely on insurance, including Medi-Cal enrollees, older adults, rural residents, and non-English speakers, compete for what’s left. So we can’t pretend the human system works, and we can’t blame people for turning to AI for support when they’re in distress. AI is filling the gap It’s estimated that roughly a quarter of AI users use it for mental health support. If you have internet, it’s available 24/7, it’s cheap, and it speaks your language. Uninsured adults are about twice as likely as insured adults to do it (30% vs. 14%). It feels anonymous in ways that may enable people to ask things they’re unsure or embarrassed about. The largely hidden, personal use makes it hard to study whether it’s actually helping people with their mental health issues, but researchers are trying. Does AI therapy work? A 2026 analysis of nearly 40 randomized trials found chatbots showed a real but small reduction in depression symptoms. But most of these trials were compared to an alternative of no therapy, not a human therapist. So the benefit of AI therapy is probably real, but modest, and mostly untested against the alternative of human contact. We need more studies. Serious concerns OpenAI’s own estimate is that more than a million ChatGPT users each week show signs of suicidal planning or intent. These are high stakes encounters, and AI doesn’t always get it right. That’s partly because a chatbot can sound like a therapist, but it has no license, no duty of care, and it’s not clear who to hold accountable when it gets things wrong. AI is also designed to help users in whatever task they’re seeking to accomplish. People may feel like they’re getting therapy, but they’re mainly getting a convincing conversation. It’s easy for an AI companion to wander into gray areas, like playing along with “creative writing” that may be about the user’s own suicidal intent. Courts are driving safety conversations A wave of lawsuits have been filed on behalf of families claiming that chatbots pushed people they loved toward self-harm, including teens who died by suicide. The first settlements came this year. OpenAI is headquartered in San Francisco, and dozens of cases alleging that ChatGPT drove users to suicide or self-harm are now before a San Francisco judge. Character.ai has filed for bankruptcy after several states brought lawsuits accusing the chatbot of pushing dangerous content to kids. But the technology seems to be improving. Last month, an independent evaluation found that newer AI models “almost never endorse suicide.” That’s progress, but our societal appetite for even one preventable death is very low. So how do we move forward? Finding a middle ground Earlier this month the governor vetoed Senate Bill 903, a bill designed to place guardrails on the use of AI for therapy. The bill would have prohibited any AI-based platform from being advertised as psychotherapy, and would have required a licensed professional to review and approve each encounter where AI was used to support therapeutic decisions. Newsom called it overly broad, since even routine screening questions would have needed clinician sign-off. Knowing we’re already short on mental health providers, requiring human review of AI encounters may not relieve our access problems. Still, the answer isn’t no oversight. Here’s one feasible short term solution. Rather than reviewing each encounter, a licensed clinician can design the guardrails: what counts as a crisis, what triggers an immediate handoff to a human, and what gets sampled for audit each month. The AI runs inside that structure. Conversations get checked, failures get reported, and a real clinician owns the framework. Medicine already has models to learn from. The FDA process for rolling out newly approved medications is an example. After a product reaches patients, we keep watching for adverse events. Patient-facing AI needs the same “digital pharmacovigilance”: systematic tracking of harms, near misses, and the types of groups that get hurt and why. It’s also critical that users know that they can reach a human if they’re in crisis. Most chatbots now include messages like these: Bottom line The rush to use unproven AI tools for mental health support is mostly a workaround, a sign of a health system people can’t get into. We need better access to proven care from licensed clinicians. That takes reimbursement that makes accepting insurance viable, and a bigger workforce. But, built and tested well, AI could be part of the answer. It could be the 2 a.m. check-in when no one else is awake, or a way for patients to practice skills their therapist taught them. It could be the first step to get someone the right level of care, and take paperwork off clinicians’ plates so they spend more time with patients. None of this is simple. The SB 903 veto doesn’t end the debate, and the legislature will be back. In the meantime, those of us using these tools need to stay informed, ask hard questions, and hold the companies building them accountable. I’ll try to do my part, and we’ll keep learning together. Love,Matt P.S. If you or someone you know is struggling with mental health challenges, emotional distress, substance use problems, or just needs to talk, call or text 988- you’ll reach a real person— or chat at 988lifeline.org 24/7. Dr. Matt Willis is the author of Your Local Epidemiologist in California. A California native, he’s served as a primary care physician, CDC epidemiologist, and public health officer for Marin County, where he guided the pandemic response. He lives in Marin with his family and their dogs, Teddy and Ramona. Thank you Cynthia He, MD, PhD, and Parnika Saxena, MD, for their guidance in preparing this article. Cynthia works in an outpatient mental health clinic, treating patients who have Medi-Cal or, sometimes, no insurance. Parnika works in an inpatient psychiatric unit, treating patients with public or private insurance or self-pay ability. All opinions are their own and do not represent their employers.

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Oct 16 • 10:32 AM EDT • Health • yourlocalepidemiologistca.substack.com
Heart Surgery Programs at Two MedStar Health Hospitals Earn Top Quality Ratings

WASHINGTON -- Two MedStar Health hospitals have earned the highest quality designation, a three-star rating, from the Society of Thoracic Surgeons (STS), placing their cardiac surgery programs among the nation’s best for patient outcomes and surgical care.

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Oct 14 • 8:45 AM EDT • Health • newswise.com
Bridging medicine and care: How China is strengthening international health partnerships

From high-risk surgical care in Benin to stroke interventions in Seychelles, Chinese medical teams abroad are increasingly moving from emergency clinical aid to long-term capacity building. Combining frontline care with specialized malaria control and cataract programs, these health partnerships focus on practical knowledge transfer and serving local populations.

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Oct 13 • 11:04 PM EDT • Health • news.cgtn.com
Dartmouth Health’s New London Hospital holds ceremonial grou...

New London Hospital has broken ground on a 40,000-square-foot Surgical Care Center, set to open in fall 2028, to expand operating capacity and keep more surgica...

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Oct 13 • 12:00 AM EDT • Health • unionleader.com
Steris to acquire Pittsburgh-area medical device maker for $2.1 billion

The Xodus Medical acquisition would add a growing surgical safety business to Steris' portfolio, with the deal expected to close by the end of the year.

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Oct 12 • 10:23 AM EDT • Business • crainscleveland.com
STAAR Surgical Appoints Andrew Pilon, OD, as Vice President of Business Development

LAKE FOREST, Calif.—STAAR Surgical Co. (NASDAQ: STAA), a leader in phakic intraocular lenses (IOLs) with its EVO family of Implantable Collamer Lenses (EVO ICL), has appointed Andrew Pilon, OD, as vice president of business development, which is a new position, the company told VMAIL. Dr. Pilon will report to Warren Foust, STAAR’s president and CEO, and work closely with the company’s senior leadership team to capitalize on opportunities that support STAAR’s innovation strategy and expand its product portfolio, according to the announcement from the company.

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Oct 11 • 8:24 PM EDT • Business • visionmonday.com
Health Check: Doctor discusses prostate cancer risk and screening for awareness month

Dr. David Mendoza, a surgical urologist, discussed prostate cancer risk factors and screening recommendations.

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Oct 8 • 10:07 AM EDT • Health • wtap.com
Health Check Prostate Cancer: Part 1

Dr. David Mendoza, a surgical urologist, discussed prostate cancer risk factors and screening recommendations.

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Oct 8 • 10:06 AM EDT • Health • wtap.com
Why a healthcare worker traded a career in hospitals for business ownership in Alexandria

After years of treating patients with preventable chronic illnesses, Nicole Batts wanted to leave the healthcare industry and help people get healthy before reaching the hospital. Batts took over ownership of Old Town's Fitness Together Alexandria (300 N Washington Street, Suite 106) in 2019. That comes after working in nursing in the surgical intensive care

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Oct 7 • 9:15 AM EDT • Business • alxnow.com
Here Are Wednesday’s Top Wall Street Analyst Research Calls: Abbott Laboratories, AppFolio, Delek US Holdings, Flutter Entertainment, Honeywell Aerospace, Intuitive Surgical, Marvell, NetApp, and More

Pre-Market Stock Futures: Futures are trading lower as today’s oil and interest rates are higher. Baseball legend Babe Ruth was often credited with the saying, “Records are made to be broken,” and Tuesday was one of those days for the stock market. For the second straight day, all major indices ended higher, with only the […]

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Oct 7 • 7:59 AM EDT • Entertainment • 247wallst.com
Delaware details still slim as Penn Medicine plans new surgery centers

Penn Medicine unveiled a new plan to bring 18 ambulatory surgical centers to the region. Details remain slim on what's coming to Delaware.

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Oct 7 • 5:44 AM EDT • Health • delawareonline.com
Atrium Health's new Affordability Protection Program lowers costs for state employees

Atrium Health's new Affordability Protection Program, effective January 1, 2027, will reduce outpatient surgical care copays and lower inpatient hospital copays.

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Oct 6 • 3:19 PM EDT • Health • wfdd.org
No. 3 Spartans Dominate Exhibition: The Eric Nilson Show

Eric Nilson’s four-point explosion and Joshua Ravensbergen’s poised debut fueled a surgical offensive display as the Spartans dismantled Boston College to signal their pursuit of another title.

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Oct 2 • 8:37 PM EDT • Sports • sports.yahoo.com
Ochsner Health doubles the number of operating rooms at Ochsner Medical Complex

Patients across the Baton Rouge region now have greater access to specialized surgical care closer to home following an expansion of the surgical center at Ochsner Medical Complex - The Grove.

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Oct 2 • 3:25 AM EDT • Health • newswise.com
Global Health & WASH: October 2026 Funding Opportunities (26 new opportunities)

41 opportunities on the Global Health & WASH page this cycle, 26 of them new. The health money on this page is mostly research money, and much of it is aimed at people early in their careers. Funder after funder, from the TANGO2 Research Foundation’s Research Pathways grants to the South African Medical Research Council’s Early Investigators Programme to the National Ataxia Foundation and Alex’s Lemonade Stand Foundation, is funding early-career investigators and the institutions that host them, with a clear tilt toward researchers based in or from the Global South, from AMBSO in Uganda to Kenya’s CONNECT-VAX network to Ersilia’s AI Incubator for African drug discovery. The money is organized by disease as much as by need: narrow foundations, the Parkinson’s Foundation, NTAP for neurofibromatosis, the RUNX1 Research Program for an inherited blood disorder, each run their own grant, so the question for an applicant is less which health problem you work on than which foundation owns your disease. The largest European cheques go to consortia only, with the European Innovation Council putting up to EUR €4 million behind a single healthy-ageing project and UNITE up to EUR €1 million behind each cross-border digital health team. Water sits apart, almost entirely in applied utility research: the Water Research Foundation’s cluster of USD $250,000 to $500,000 projects, each built around a utility problem from sewer laterals to reuse treatment. And the biggest single pot is public: HRSA is renewing community health center service areas with awards of up to USD $10 million each. This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. Open Opportunities 2027 Building the Field of Health Advocacy Grant, Georgia Health Initiative. *New!* *Closing soon!* Georgia Health Initiative, a nonprofit private foundation focused on health equity, is opening its 2027 Building the Field of Health Advocacy Grant to strengthen the organizations that push for healthier systems across the state. The Initiative treats advocacy as infrastructure, backing one-year projects that range from urgent responses to shifting federal policy to longer arc campaigns on housing, behavioral health, care access, and food security. It wants coalitions that elevate community voice, apply an equity lens, and arrive ready to deploy concrete strategies, and it deliberately seeks variety in issues, communities, and organizational size. The optional webinar and required lobbying training signal a funder investing in a durable field, not one grant cycle. The strongest fits are Georgia nonprofits and public agencies ready to turn advocacy readiness into systems change. Geographies: United States. Who can apply: Tax-exempt 501(c)(3) public charities, state or local government agencies, or coalitions/collaboratives using a 501(c)(3) fiscal sponsor, that work in Georgia on behalf of Georgians and align with the mission, vision, and values of Georgia Health Initiative. Only one application per organization, though an organization may be listed as a partner or subcontractor on multiple applications. Funding amount: Organizations can apply for up to USD $80,000 per project; the Initiative anticipates investing a total of USD $1.36 million. Targeted Sectors / SDGs: Governance, Policy & Advocacy · SDG3; SDG10. Deadline: October 2, 2026. Learn more and apply here. TDD Research Pathways Grant, TANGO2 Research Foundation. *New!* *Closing soon!* The TANGO2 Research Foundation, working with a founding gift from Tango2UK, is opening its TDD Research Pathways Grant to fund early-career investigators anywhere in the world who study TANGO2 Deficiency Disorder. The foundation is using this money to seed pilot work and to build a research community around a rare disorder that few labs currently study. It wants to back emerging scientists, clinicians, and trainees who will stay with this field, not one-off projects, which is why it requires a committed mentor and real institutional support and asks each applicant for a plan for future contributions. The design rewards promise and persistence over track record. The strongest fits are students, residents, postdoctoral fellows, and new investigators ready to commit to TANGO2 research. Geographies: Global. Who can apply: Early-career investigators worldwide, including undergraduate, graduate, and medical trainees, postdoctoral fellows, residents, and clinical or research fellows. Early-career investigators must hold a PhD, MD, or equivalent doctoral degree and be within 10 years of that degree or within 5 years of initiating rare disease research, engaged in postdoctoral research at an academic institution, teaching hospital, or nonprofit research institute. Currently enrolled trainees and transitional PhD candidates beginning a postdoctoral appointment at a nonprofit institution by July 1, 2026 are also eligible. All applicants must identify a qualified mentor with relevant TDD or rare disease research experience and demonstrate institutional support. Funding amount: Up to USD $15,000. Targeted Sectors / SDGs: Innovation, Science & Technology. Deadline: October 2, 2026. Learn more and apply here. Call for Expression of Interest (EOI): AMBSO Impact Research Initiative, Africa Medical and Behavioral Sciences Organization (AMBSO). *Closing soon!* The Africa Medical and Behavioral Sciences Organization is inviting expressions of interest for its Impact Research Initiative, which funds early-stage pilot studies and proof of concept work on priority health challenges. AMBSO is a Ugandan research organization backing bold ideas that can grow into larger studies, and its tracks span antimicrobial resistance, epidemic preparedness, artificial intelligence for diagnostics, HIV prevention, climate and health, cancer, maternal and child health, and non-communicable diseases. The small award size and direct-cost-only rule point to a funder that wants evidence rather than overhead, and that favors projects able to attract follow-on money or use AMBSO’s own research infrastructure. Eligibility runs worldwide, welcoming researchers and institutions inside and outside Africa. The strongest fits are researchers with a feasible pilot that generates policy-ready evidence. Geographies: Global. Who can apply: Open worldwide to researchers, academic institutions, and research organizations whose work aligns with generating high-impact health evidence. Independent researchers are eligible if affiliated with an academic or research institution. Doctoral students are encouraged to apply as part of a research team led by a faculty Principal Investigator. Community-based organizations and other eligible entities may apply. Projects may be implemented inside or outside Uganda. Funding amount: Up to USD $10,000 per project, with no minimum funding threshold. Targeted Sectors / SDGs: SDG3. Deadline: October 2, 2026. Learn more and apply here. Entrepreneurs for Resilience 2027 (E4R27), Swiss Re Foundation. *Closing soon!* Swiss Re Foundation is opening the tenth edition of Entrepreneurs for Resilience, which backs healthcare social enterprises expanding affordable, quality primary care for low-income communities across low- and middle-income countries. The Foundation is using catalytic, blended funding plus multi-year advisory to take risk out of scaling, helping proven models reach more people sustainably rather than stay stuck at pilot size. It looks to back brick-and-click enterprises that pair physical care with digital tools and build affordability through savings, payments, or microinsurance, ideally integrated with public health systems. Requiring earned revenue, real customer scale, and gender-inclusive teams signals that this is growth capital for commercially serious ventures, not seed money. The strongest fits are established, revenue-generating healthcare enterprises ready to scale access for underserved populations. Geographies: Global. Who can apply: For-profit and hybrid healthcare social enterprises serving low-income and underserved populations in low- and middle-income countries, using combined physical and digital (brick-and-click) healthcare delivery models. Applicants must demonstrate measurable social impact, generate at least 50% of income through earned revenue, have been established no later than December 2023, already serve at least 50,000 people with potential to scale, and have at least 30% low-income customers. Preference for gender-inclusive enterprises with at least one female founder or at least 30% women in management. Funding amount: Pilot funding of up to USD $45,000 for the 6-8 shortlisted social enterprises; up to USD $1 million in blended funding (up to USD $600,000 unconditional plus up to USD $400,000 conditional) shared among 3-4 finalists over a two-year implementation period; total programme funding approximately USD $1.3 million. Targeted Sectors / SDGs: Innovation, Science & Technology · SDG3; SDG5. Deadline: October 4, 2026. Learn more and apply here. Horizon HealthTech 2026, IIITD Innovation & Incubation Center. *Closing soon!* IIITD Innovation and Incubation Center is opening Horizon HealthTech 2026, a nine-month MedTech incubation cohort run under the aegis of BIRAC EDGE for founders building medical devices, diagnostics, surgical and interventional tools, or remote monitoring. The center is backing teams that already hold a validated proof of concept and want to reach a tested prototype, pairing each founder with a named expert and clinical validation through a hospital partner. What they seek to back is Indian health technology that can survive real clinical scrutiny and regulatory review, not slideware. The structure, with lab access, CDSCO guidance, IP support, and investor connects, signals a program built to make startups ready for follow-on capital. The strongest fits are early-stage MedTech teams with defensible IP and a working path from bench to bedside. Geographies: India. Who can apply: Early-stage teams/startups with a validated idea/proof of concept (TRL 3 onwards) working on medical devices, diagnostics, surgical/interventional technologies, or remote monitoring, holding IP or with potential to generate IP. Funding amount: No cash award amount is stated on the official program page. Benefits are in-kind: prototyping lab and equipment access, clinical/hospital validation (Max Healthcare), expert mentorship, CDSCO regulatory guidance, IP filing support, workspace, cloud credits and tools, and investor connects. Run under the aegis of BIRAC EDGE and builds a path to follow-on Government/VC/Angel funding. Targeted Sectors / SDGs: Innovation, Science & Technology · SDG3; SDG9. Deadline: October 5, 2026. Learn more and apply here. OpenAI AI and Teen Development Research Grant Program, OpenAI. *New!* *Closing soon!* OpenAI is opening its AI and Teen Development Research Grant Program to fund independent studies of how generative AI shapes the lives of young people ages 13 to 17. OpenAI wants a stronger evidence base on how teens actually use these tools and what that use does to their social and emotional development, so that product teams, policymakers, and regulators can act on findings rather than assumptions. It seeks work on emotion regulation, relationships, belonging, and the safeguards that keep teens safer, welcoming interdisciplinary teams and any methodology. That it will fund research whose conclusions may not favor AI providers, and prioritizes studies touching ChatGPT, signals a genuine appetite for credible outside scrutiny. The strongest fits are research groups grounded in adolescent development, well-being, and AI safety. Geographies: Global. Who can apply: Researchers aged 18 or older who are affiliated with a research institution or organization, and/or have significant experience relevant to child or adolescent development, well-being, human-computer interaction, AI impacts, or a closely related field. Multiple institutions may collaborate. OpenAI is seeking to fund research rather than for-profit initiatives and will not prioritize for-profit organizations. Funding amount: Individual research grants up to USD $1 million, totaling up to USD $5 million; maximum 10% of each grant for overhead or indirect costs. Targeted Sectors / SDGs: Social Inclusion & Community Wellbeing; Innovation, Science & Technology. Deadline: October 6, 2026. Learn more and apply here.

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Oct 1 • 6:29 AM EDT • Health • impactfunding.substack.com
Case Mgmt Profiles – Broward Health Imperial Point – Claudia Wenger, RN

For Claudia Wenger, RN, case management is about seeing the whole picture and helping patients and families find their way forward. A nurse since 1990, Wenger spent years at the bedside, gaining experience throughout the hospital on medical-surgical floors, the ICU and emergency room, before transitioning to case management 20 years ago. That clinical experience […]

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Oct 1 • 1:03 AM EDT • Health • southfloridahospitalnews.com
Junney Baeza Dager, MD, Joins Baptist Health Miami Neuroscience Institute as a Nonsurgical Spine Care Physician

Junney Baeza Dager, M.D., has joined Baptist Health Miami Neuroscience Institute at Baptist Health Brain & Spine Care as a nonsurgical spine care physician. Dr. Baeza Dager earned her medical degree from the University of Cartagena School of Medicine in Colombia. After completing a transitional-year internship at St. Vincent of Paul University Hospital in Medellin, […]

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Oct 1 • 1:01 AM EDT • Health • southfloridahospitalnews.com
Junney Baeza Dager, M.D., Joins Baptist Health Miami Neuroscience Institute as a Nonsurgical Spine Care Physician

August 31, 2026 – Junney Baeza Dager, M.D., has joined Baptist Health Miami Neuroscience Institute at Baptist Health Brain & Spine Care as a nonsurgical spine care physician. Board-certified in physical medicine and rehabilitation with specialized expertise in spinal cord injury medicine, Dr. Baeza Dager focuses on helping people with neurological conditions improve their function, […]

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Sep 30 • 9:35 AM EDT • Health • southfloridahospitalnews.com
Nathan J. Nordmann, M.D., Joins Baptist Health Miami Neuroscience Institute as Director of Spinal Oncology and Co-Director of Spinal Radiosurgery

August 27, 2026 – Fellowship-trained neurosurgeon Nathan J. Nordmann, M.D., has joined Baptist Health Miami Neuroscience as director of spinal oncology and co-director of spinal radiosurgery. He specializes in the surgical treatment of conditions affecting the brain and spine, with advanced expertise in primary and metastatic spinal tumors, complex spinal pathology and minimally invasive surgical techniques. […]

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Sep 30 • 9:32 AM EDT • Health • southfloridahospitalnews.com
Bradish to undergo sports hernia surgery after ending '26 on IL

BALTIMORE -- Kyle Bradish's offseason will begin with a surgical procedure that will be followed by a lengthy recovery process. On Monday, Orioles president of baseball operations Mike Elias announced that Bradish is set to undergo sports hernia surgery. The procedure will be performed by Dr. William Meyers on Tuesday

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Sep 28 • 2:52 PM EDT • Sports • mlb.com
A 14-year-old in a Colorado farm town built a robotic hand from LEGO bricks, fishing line and surgical tubing, then met a 7-year-old at a science fair wearing an $80,000 prosthetic arm she had already outgrown — his next version, 3D-printed, came in under $400, and NASA took him on as an intern at 17

When a teenager's LEGO creation outperformed a prosthetic costing two hundred times more, he realized the gap between innovation and access wasn't about engineering—it was about economics.

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Sep 21 • 11:19 PM EDT • Science • scienceblog.com
Trevor Lawrence surgical in Week 1 rout

Trevor Lawrence registered four touchdowns in Week 1 victory vs. Browns

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Sep 13 • 4:59 PM EDT • Sports • sports.yahoo.com
As elective surgical volumes drag in 2026, health system execs say solid demand is still in sight

Though surgical volumes were a sore spot for major for-profit health systems in the opening half of 2026, executives said this week they are optimistic those service lines will stay afloat for the | In fireside chats this week, leaders of the country's largest for-profit systems acknowledged a slowdown in demand that will generally continue through 2026. They also affirmed continued investments to meet future anticipated demand, particularly in ambulatory settings.

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Sep 10 • 9:00 AM EDT • Health • fiercehealthcare.com
MedStar Health Offers New Nonsurgical Weight-Loss Procedure

/PRNewswire/ -- For the first time at MedStar Health, patients struggling with obesity who may not want, or may not qualify for traditional bariatric surgery,...

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Sep 9 • 5:58 PM EDT • Health • prnewswire.com
Mental health care before, after surgery improves recovery in older adults

A WashU Medicine clinical trial supports adding mental health coaching and medication cleanup to routine pre-surgical care.

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Sep 9 • 11:00 AM EDT • Health • medicine.washu.edu
Endoscopic Nipple-Sparing Mastectomy Now Available at Boulder Community Health

Susan Hagen, MD, FACS of BCH’s Boulder Valley Surgical Associates (BVSA) recently performed the first E-NSM procedures in Colorado.

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Sep 7 • 4:40 PM EDT • Health • yellowscene.com
Is UT Tyler Specialty Expansion Reframing the Investment Case for Ardent Health (ARDT)?

Ardent Health recently marked a milestone in its East Texas partnership as UT Health East Texas expanded specialty care into the UT Tyler School of Medicine Building in Tyler, bringing women’s health, pulmonary, orthopedic, imaging and surgical services alongside the region’s first medical school. This integration of patient care and physician training, supported by more than US$315 million of capital investment since 2018 and a provider network that has grown by 116%, underscores Ardent’s...

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Sep 5 • 12:25 PM EDT • Health • simplywall.st
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Adult Post-operative Mental Health Outcomes Following Abdominal and Orthopedic Surgeries: A Scoping Review

Poor mental health has been shown to negatively impact surgical outcomes; however, the impact of surgery on mental health remains under-investigated. Therefore, in this scoping review, we aimed ...

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Sep 4 • 8:00 PM EDT • Health • cureus.com
FDA clears Stryker's ‘surgical cockpit’ that uses Apple's VR headset, Vision Pro

In this edition of STAT Health Tech: Stryker deploys Apple's VR headset Vision Pro for a surgical use case, chatbots for loneliness, and more.

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Sep 1 • 9:10 AM EDT • Health • statnews.com
Welsh Gender Service surgical referrals paused for clinical review

Data suggests "significantly higher" rates of referral for gender-affirming surgery compared with English services, according to the health board.

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Aug 29 • 7:38 AM EDT • Health • bbc.com
ASC operator Regent Surgical embraces outpatient EP ablation services after CMS policy change

This new partnership provides an early look at how the field of electrophysiology is evolving in 2026 and beyond.

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Aug 26 • 12:59 PM EDT • Business • cardiovascularbusiness.com
Cancer doctor reveals 5 habits that may reduce disease risk and improve outcomes

A breast surgical oncologist shares five everyday strategies to reduce cancer risk, including how GLP-1 drugs like Ozempic could play a role.

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Aug 19 • 9:48 PM EDT • Health • foxnews.com
HCM drug advances have been a breakthrough—but more invasive treatments are still vital

Some HCM experts are concerned about the potential loss of surgical and interventional expertise as procedural volumes decline.

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Aug 19 • 5:27 PM EDT • Business • cardiovascularbusiness.com
Small Business Spotlight: Specialty dental practice takes root on Market St.

WHAT MADE YOU WANT TO OPEN BLUE HERON ROOT CANAL SPECIALISTS? OWNER SARAH ERMOSHKIN: “I’ve always been an entrepreneur at heart. When I was 23 years old, I owned a cafe in Seattle, where I even fought to oppose oppressive sales taxes on espresso drinks. After selling that business, I got married and started a family. Once my children were in school, I attended dental school through the Navy Health Professions Scholarship Program (HPSP), which covered my tuition and provided a stipend. From the beginning, my goal was to eventually own my own practice after completing my military service. The work I do is incredibly rewarding and being able to create an environment that puts patients first while helping employees grow professionally makes every day as a business owner meaningful.” WHAT DOES YOUR BUSINESS PROVIDE? ERMOSHKIN: “Endodontists are often called ‘pain doctors’ because our primary mission is to relieve pain and save natural teeth. We specialize in root canal therapy, retreatment of nonhealing root canals, treatment of root resorption, apicoectomies – microsurgical root-end procedures – and vital pulp therapy for children. Our goal is to preserve teeth that might otherwise need to be extracted and replaced with implants. Saving a patient’s natural tooth is almost always the best long-term solution for their oral health.” HOW DOES YOUR MILITARY TRAINING HELP YOUR BUSINESS? ERMOSHKIN: “My military service taught me how to lead, collaborate and make decisions under pressure. I worked closely with senior leadership while treating a large patient population and collaborating with specialists across multiple disciplines. During the COVID-19 pandemic, (I) served a dual role as Navy dentist and as the public affairs officer for Naval Health Clinic Annapolis, where I helped develop medical and dental communications for the midshipmen and support staff, while coordinating with the broader Navy Capital Region. We worked closely with other military treatment facilities to share best practices and deliver consistent public health messaging. Those leadership experiences continue to shape how I lead my team and serve our patients today.” WHAT CHALLENGES ARE YOU FACING RIGHT NOW IN YOUR BUSINESS? ERMOSHKIN: “One of our biggest challenges is overcoming the misinformation surrounding root canal treatment. Root canals are safe, effective and often the best way to relieve pain while preserving a natural tooth. Unfortunately, many people choose extraction because they believe it’s less expensive or because they’ve seen misleading information online. What they may not realize is that losing a tooth can lead to shifting teeth, changes in the way they bite and chew and significantly higher costs to restore their smile later.”

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Aug 12 • 9:21 AM EDT • Business • wilmingtonbiz.com
Dallas Hair Replacement for Business Professionals Offers Non-Surgical Hair Replacement for Men

Look Sharp, Stay Competitive. Restore your confidence with non-surgical hair replacement in Dallas.Dallas, TX, Aug. 10, 2026 (GLOBE NEWSWIRE) -- In the competitive business environment of Dallas, confidence and success go hand in hand. Whether you're presenting in the boardroom, networking at a conference, or closing a major deal, how you look plays a critical role in your self-esteem, which in turn affects how others perceive you. If you're a busy executive or professional experiencing hair los

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Aug 10 • 4:47 PM EDT • Business • finance.yahoo.com
Southwoods Health completes expansion project at The Surgical Hospital

Southwoods Health has completed a multimillion-dollar, 40,000-square-foot expansion project at The Surgical Hospital.

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Aug 8 • 9:10 AM EDT • Health • wkbn.com
Carmen Solórzano and David Penson to serve in top surgical posts

Carmen Solórzano has been chosen to serve as Interim Chair of the Section of Surgical Sciences, while David Penson has been chosen to serve as Interim System Surgeon-in-Chief for Vanderbilt Health.

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Aug 4 • 11:35 AM EDT • Health • news.vumc.org
How Health Systems Can Navigate the Outpatient Surgery Shift

Discover strategies to protect revenue, strengthen physician partnerships and compete as surgical care increasingly moves to outpatient settings.

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Aug 3 • 1:43 AM EDT • Health • modernhealthcare.com
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Chiefs QB Patrick Mahomes Raises Concern With Actions at Practice

Some Kansas City Chiefs fans expressed worry that Patrick Mahomes is pushing his surgically repaired leg too far. The post Chiefs QB Patrick Mahomes Raises Concern With Actions at Practice appeared first on HEAVY.

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Jul 31 • 2:30 AM EDT • Sports • sports.yahoo.com
Safety a top priority as more heart procedures move to outpatient settings

The push to move certain procedures to ambulatory surgical centers is one of the biggest business trends in electrophysiology. Medical societies are watching this space closely to ensure high quality remains the goal.

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Jul 30 • 12:41 PM EDT • Business • cardiovascularbusiness.com
‘To play God’: Cuba’s healthcare system collapses under US pressure

As the Trump administration tightens US sanctions, Cuba's healthcare sector struggles with fuel and supply shortages.

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Jul 30 • 12:34 PM EDT • Health • aljazeera.com
At UW Health and other hospitals, apprentices are increasingly common

UW Health in Madison created a company called WorkForward to help others set up apprenticeships and fill job openings for nurses, surgical techs and more.

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Jul 26 • 6:00 AM EDT • Health • captimes.com
Duke Health brings new clinic to underserved city

Duke Health brings new outpatient clinic for surgical patients to an underserved city outside of Charlotte

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Jul 25 • 12:24 PM EDT • Health • spectrumlocalnews.com
UW Health thinks Wisconsin’s health apprenticeships can become model

To fill openings for nurses, surgical techs and more, UW Health pays staff to train for new careers, on the clock. It wants to show others how it’s done.

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Jul 23 • 6:00 PM EDT • Health • milwaukeenns.org
Surgeon hails new CABG technology as a 'technical breakthrough'

The new-look ELANA device from AMT Medical could simplify CABG procedures and help improve patient access to minimally invasive and robotic surgical techniques.

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Jul 22 • 5:50 PM EDT • Business • cardiovascularbusiness.com
Sharks, sutures & science

From learning how to do surgical sutures on a silicone mat to exploring the anatomy of sharks, frogs and other animals, students are diving into hands-on wildlife science this summer during the Clinic for the Rehabilitation of Wildlife's Conservation Summer Camp. With various camps designed for students in kindergarten through 12th grade, CROW's annual camp combines wildlife conservation, veterinary medicine and outdoor discovery through

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Jul 19 • 2:30 PM EDT • Science • floridaweekly.com
Less sleep = less health; Led Zeppelin in the OR; dangers of people-pleasing; plus other stories with Vanderbilt Health sources

Prevention interviewed Beth Malow, MD, Professor of Neurology and Pediatrics in the Vanderbilt Sleep Division, for a story about two randomized trials published in Annals of Internal Medicinethat found decreasing sleep by just 1.5 hours each night was linked with increases in body weight, waist circumference, and sedentary time in adults with elevated cardiometabolic risk. Yahoo Healthalso picked up the story. WTVF News Channel 5 reporter Nikki Hauser interviewed Ashish Shah, MD, Professor and Chair of Cardiac Surgery, for a new video podcast series called “Why Nashville” where she interviews interesting people doing interesting work about why they came to Nashville and how it is going. Among the revelations: his go-to OR music includes Led Zeppelin and AC/DC. Everyday Health interviewed Aaron Brinen, PsyD, Assistant Professor of Psychiatry and Behavioral Sciences, for a story about the TikTok trend that encourages women to speak up about their concerns or they’ll develop an autoimmune disease. Overall, people suggest that suppressing feelings of anger, minimizing your own needs, or people-pleasing raises your risk. Telemundo Nashville broadcast a story on cyclosporiasis that quotes both William Schaffner, MD, professor of Preventive Medicine, and Juan C. Salazar, MD, MPH, chair of the Department of Pediatrics and system Pediatrician-in-Chief for Monroe Carell Jr. Children’s Hospital at Vanderbilt. Schaffner also spoke to WKRN News 2 about measles and The Cutabout shingles and long distance running. WREG (Memphis) and others picked up the measles story as well. CNN reporter Deidre McPhillips interviewed John Trahanas, MD, Assistant Professor of Cardiac Surgery, and Director of Thoracic Aortic Surgery, for a story about aortic dissection in last week’s death of U.S. Sen. Lindsey Graham. The Nashville Post published a story by freelance reporter Leah Hunter on robotic surgery, including a patient story and numerous quotes from Sekhar Padmanabhan, MD, Assistant Professor of Surgery in the Division of Surgical Oncology.

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Jul 17 • 12:27 PM EDT • Health • news.vumc.org
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Oral health advocates try to unravel mystery of two NC budget paragraphs

A budget provision about dental Medicaid services, ambulatory surgical centers confounds oral health organizations, advocates.

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Jul 17 • 4:22 AM EDT • Health • northcarolinahealthnews.org
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Medtronic recalls surgical devices due to risk of blood contamination

Trace amounts of blood were identified within the sealed packaging of these devices. No patients were exposed to the foreign material, and no adverse events were reported, but Medtronic is recalling the devices as a precaution.

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Jul 16 • 4:43 PM EDT • Business • cardiovascularbusiness.com
Here Are Thursday’s Best Wall Street Analyst Research Calls: Align Technology, American Tower, Caesars Entertainment, Cohu, Five Below, Intuitive Surgical, Salesforce, Toast, and More

Pre-Market Stock Futures: Futures are trading mixed after another tough day across Wall Street, with all the major indices crushed early on, before the Nasdaq made a late-afternoon push to wind up just modestly higher at 25,870, up 0.20%. The S&P 500 also rallied in the afternoon, erasing a big deficit, to finish the session ... Here Are Thursday’s Best Wall Street Analyst Research Calls: Align Technology, American Tower, Caesars Entertainment, Cohu, Five Below, Intuitive Surgical, Salesforce, Toast, and More

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Jul 9 • 7:52 AM EDT • Entertainment • 247wallst.com
NYC Health + Hospitals/Queens Receives the PRISM Award from the Academy of Medical-Surgical Nurses

NYC Health + Hospitals/Queens today announced that its Medical-Surgical Unit, 5B East, has received the prestigious PRISM Award from the Academy of

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Jul 1 • 1:00 PM EDT • Health • nychealthandhospitals.org
AI Roadshow — An AI Ally for Human Health

Join Argonne National Laboratory and The International Museum for Surgical Science for An AI Ally for Human Health.

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Jul 1 • 9:00 AM EDT • Health • anl.gov
Vanderbilt Health performs nation’s first breast cancer surgery using intraoperative PET-CT scan technology

The novel imaging technology provides surgical teams with a real-time view of tumor margins in the operating room.

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Jun 30 • 10:23 AM EDT • Health • news.vumc.org
Think Insurance Denials Only Hurt Patients? Why Business Owners Are Paying the Ultimate Price

A simple 9-week delay for a critical medication resulted in a $50,000 surgical nightmare. Here is how healthcare bureaucratic delays quietly destroy your company's bottom line.

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Jun 30 • 5:00 AM EDT • Business • inc.com
FDA approves surgical device for high-risk aortic procedures

The AMDS Hybrid Prosthesis was designed to help clinicians treat DeBakey Type 1 dissections complicated by malperfusion. It works as a complement to hemiarch replacement, preserving the native arch and making reinterventions possible if needed.

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Jun 29 • 1:23 PM EDT • Business • cardiovascularbusiness.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Oracle Health Extends AI into the Operating Room in Collaboration with Theator

/PRNewswire/ -- Oracle Health and Theator are working together to provide AI-powered surgical intelligence solutions to Oracle Health customers in the U.S....

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Jun 24 • 8:05 AM EDT • Health • prnewswire.com
Penicillin Allergy Labels May Pose Health Risks in Kids

Children with a penicillin allergy label have higher rates of methicillin-resistant Staphylococcus aureus colonization, surgical site infections, and all-cause mortality than those without the label.

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Jun 21 • 8:00 PM EDT • Health • medscape.com
Scientists found a cannabis compound that relieves pain without the high

Compounds responsible for the aroma of cannabis and many other plants may offer a surprising new way to relieve chronic pain. Researchers found that several cannabis-derived terpenes significantly reduced pain in mouse models of fibromyalgia and post-surgical pain, with one terpene, geraniol, showing especially strong effects. Unlike THC, these compounds are not associated with psychoactive effects, making them a potentially attractive alternative for pain treatment.

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Jun 20 • 8:00 AM EDT • Science • sciencedaily.com
There aren’t enough cadavers to teach medical students. Surgical Science wants to help

The company makes surgical simulations that teach students how to operate on humans.

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Jun 16 • 2:51 PM EDT • Science • healthcare-brew.com
Essentia Health hosting back pain seminar in Fargo

Essentia Health on Tuesday, June 16, will host a seminar in Fargo highlighting available surgical and non-surgical options for back pain.

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Jun 9 • 11:08 AM EDT • Health • essentiahealth.org
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Surgical technologist apprenticeship helps stay at home mom rejoin workforce

A stay-at-home mom of three home-schooled children, Rebecca Johnson was looking to rejoin the workforce, preferably in the medical field.

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Jun 5 • 11:22 AM EDT • Health • essentiahealth.org
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Marshall Health Network, Intermed Labs advance next-generation surgical visualization through spatial arthroscopy

HUNTINGTON, W.Va. – Marshall Health Network, in collaboration with Intermed Labs (IL), has announced the development of spatial arthroscopy, an innovative technology designed to transform how surgeons visualize and interact with minimally invasive procedures. The project, currently in development, was conceptualized by Chad D. Lavender, M.D., and represents a new frontier in surgical ergonomics and digital […]

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Jun 3 • 3:51 PM EDT • Health • news.marshallhealth.org
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Biodegradable brain probes eliminate the need for risky surgical removal

Soft and flexible brain sensors that naturally dissolve away after a few weeks could make surgical removal obsolete.

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Jun 1 • 1:03 AM EDT • Science • advancedsciencenews.com
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Medtronic recalls thousands of surgical devices due to contamination risk

This Class II recall includes more than 18,000 cannulae used during cardiac surgery.

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May 21 • 12:03 PM EDT • Business • cardiovascularbusiness.com
Surgical patients with mental health conditions who receive music therapy are more medically complex, study finds

A new study from University Hospitals Connor Whole Health found that patients with mental health and/or substance use disorders who undergo surgery and receive music therapy are more medically complex ...

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May 18 • 11:20 PM EDT • Health • medicalxpress.com
New Exhibit at International Museum of Surgical Science Highlights Role of Filipino Nurses in Healthcare

“Unheard Voices of Care: Filipino Nurses in America” runs until Aug. 2 at the International Museum of Surgical Science. The exhibit highlights stories of Filipino nurses from the 1940s to present day.

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May 18 • 3:57 PM EDT • Science • news.wttw.com
Brian Christine Is a Penile Implant Expert Giving Updates on Hanavirus

Dr. Brian Christine, a prominent figure in the American hantavirus response, is a surgical urologist with little background in public health.

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May 15 • 1:18 PM EDT • Health • rollingstone.com
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Study links air pollution to worse post-surgical outcomes

Results could inform Utah environmental policy and ultimately help keep people healthy after surgery.

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May 8 • 12:23 PM EDT • Health • attheu.utah.edu
Resilia tissue developed by Edwards Lifesciences associated with long-term durability

Kevin Accola, MD, spoke to Cardiovascular Business about new 10-year data on the performance of surgical valves featuring Resilia tissue. The findings are good news for Edwards Lifesciences, which also includes the tissue on many of its TAVR devices.

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May 6 • 5:21 PM EDT • Business • cardiovascularbusiness.com
SGMC Health Names Thomas Director of Nursing

SGMC Health announces the promotion of Stefanie Thomas to Director of Nursing. In this role, she will oversee medical-surgical nursing units

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May 6 • 4:10 PM EDT • Health • sgmc.org
Patient-centric health care ‘bundles’ can improve outcomes and cut costs

MyHealth Bundles have cut waiting times, improved maternity care and nonsurgical management of osteoarthritis, and saved patients and employers millions of dollars.

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May 5 • 3:36 PM EDT • Health • news.vumc.org
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Apple Vision Pro Used in World-First Cataract Surgery

Apple's Vision Pro has hit another medical-use milestone, with a New York ophthalmologist becoming the first surgeon to perform cataract surgery using the spatial computing headset. Dr. Eric Rosenberg of SightMD completed the initial procedure in October 2025 and has since performed hundreds of additional cases using ScopeXR, a surgical platform he co-developed for Apple's mixed reality device.

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Apr 28 • 10:51 AM EDT • Technology • macrumors.com
Inside the endoscopic revolution in weight loss

Article explains how bariatric endoscopy — including endoscopic sleeve gastroplasty and transoral outlet reduction — combined with metabolic therapies and GLP-1 receptor agonists is expanding nonsurgical obesity treatment options and reframing obesity as a chronic, multifactorial disease.

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Apr 27 • 8:00 AM EDT • Health • uclahealth.org
Algeria eliminates trachoma as a public health problem

The World Health Organization (WHO) reports validating Algeria as having eliminated trachoma as a public health problem. This makes Algeria the 29th country globally to achieve this significant milestone. "Algeria’s elimination of trachoma is a historic triumph that connects the past, present, and future of public health, and is rooted in a century-long commitment," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "This milestone proves that with sustained political will and on-the-ground leadership from committed health professionals, we can eliminate neglected tropical diseases and build a healthier, more resilient future for all." For decades, Algeria implemented the WHO-recommended SAFE strategy to eliminate trachoma. These activities included provision of surgery to treat the late blinding stage of the disease (“trachomatous trichiasis”, TT), conducting mass administration of antibiotic treatment, carrying out public awareness campaigns to promote facial cleanliness and personal hygiene as well as improvement in access to water supply and sanitation. Trachoma is the first neglected tropical disease to be eliminated in Algeria. Trachoma is a disease of the eye caused by infection with the bacterium Chlamydia trachomatis. It is a public health problem in 30 countries and is responsible for the blindness or visual impairment of about 1.9 million people. Blindness from trachoma is difficult to reverse. Based on November 2025 data, 97 million people live in trachoma endemic areas and are at risk of trachoma blindness. Infection spreads through personal contact (via hands, clothes, bedding or hard surfaces) and by flies that have been in contact with discharge from the eyes or nose of an infected person. With repeated episodes of infection over many years, the eyelashes may be drawn in so that they rub on the surface of the eye. This causes pain and may permanently damage the cornea. In 2024, 87,349 people received surgical treatment for advanced stage of the disease, and 44.4 million people were treated with antibiotics. Global antibiotic coverage in 2024 was 39%. Outbreak News Today is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe

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Apr 25 • 9:32 PM EDT • Health • outbreaknewstoday.substack.com
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Jermod McCoy says doctors that did surgery told him knee is healthy for NFL

Jermod McCoy said doctors told him his surgically-repaired knee is healthy and ready for the NFL, but he'll let the Raiders decide what's next.

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Apr 25 • 3:33 PM EDT • Health • knoxnews.com
Marshall Health Network enrolling patients in lung cancer clinical trial evaluating personalized immunotherapy approach

lungllulungHUNTINGTON, W.Va. – The Edwards Cancer Institute at Marshall Health Network (MHN) is enrolling eligible patients in a clinical trial evaluating whether a personalized immunotherapy approach can enhance the effectiveness of treatment following lung cancer surgery. The study is investigating the use of an individualized therapy designed with a tumor’s unique biology from a surgical sample to help the immune system better […]

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Apr 23 • 11:14 PM EDT • Health • news.marshallhealth.org
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Vanderbilt Health’s Seth Karp To Join Beth Israel Deaconess Medical Center and Dana-Farber Cancer Institute

After 15 years of distinguished leadership at Vanderbilt Health, Seth Karp, MD, the H. William Scott Jr. Professor of Surgery, will be stepping down as System Surgeon-in-Chief and Chair of the Section of Surgical Sciences on Oct. 15.

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Apr 23 • 5:51 PM EDT • Health • news.vumc.org
NYC Health + Hospitals/Bellevue Unveils Five New Orthopedic Surgical Tables to Enhance Patient Care and Safety - NYC Health + Hospitals

NYC Health + Hospitals/Bellevue today unveiled five new orthopedic surgical tables following a $500,000 internal investment, advancing patient safety,

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Apr 15 • 10:22 AM EDT • Health • nychealthandhospitals.org
Advancing Metabolic Health Through Coordinated Care

The Metabolic Health Institute is a first-of-its-kind model unifying endocrinology, obesity medicine and bariatric surgery under non-surgical leadership.

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Apr 14 • 8:00 AM EDT • Health • adventhealth.com
Towards better vision: WHO South-East Asia regional meeting on eye health

The WHO South-East Asia Regional Meeting on Eye Health was convened to address the substantial and persistent burden of avoidable vision impairment in the Region. South-East Asia accountsfor nearly one third of the world’s blind and visually impaired population, with cataract, uncorrected refractive error, and diabetic retinopathy contributing to more than 90 percent of cases. The meeting responded to the need for coordinated action to achieve the 2030 global targets for effective cataract surgical coverage and effective refractive error coverage, and to advance implementation of the Regional Action Plan for Integrated People Centred Eye Care. It provided a platform for reviewing progress, identifying system gaps, and strengthening country pathways to accelerate universal access to quality eye care.

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Apr 13 • 8:00 PM EDT • Health • who.int
ECU Health Medical Center Surgical Intensive Care Unit earns Beacon Award for Excellence

National award from American Association of Critical-Care Nurses recognizes exceptional patient care

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Apr 13 • 11:00 AM EDT • Health • ecuhealth.org
Dear Abby | Eye exams can save more than your vision

Dear Abby: I'm an ophthalmologist, a physician who specializes in medical and surgical eye care, and I'm hoping you can help me debunk a common myth about eye health. Many

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Apr 11 • 10:00 AM EDT • Entertainment • wenatcheeworld.com
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SGMC Health Enhances Hip Replacement Surgery with IntelliJoint® HIP Technology

SGMC Health is advancing orthopedic surgical care in South Georgia with the utilization of IntelliJoint® HIP, an advanced technology used during hip replacement surgery by orthopedic surgeon Anthony D’Abarno, DO. Hip […]

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Apr 7 • 3:06 PM EDT • Health • sgmc.org
Sacramento’s Sutter Health settles feds’ drug violations probe at two facilities

Investigators found hundreds of violations at Sutter Medical Center in Sacramento and a surgical center in Fairfield.

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Mar 30 • 5:49 PM EDT • Health • sacbee.com
Vanderbilt Lung Transplant Program sets new record

The Vanderbilt Transplant Center is now the second largest lung transplant center in the United States by volume, with 149 lung transplants in 2025, the most ever in one year at Vanderbilt Health. The Vanderbilt Lung Transplant Program leads the nation in organ preservation and regeneration and is among the best in long-term outcomes, demonstrating the success of the interdisciplinary team in caring for these complex patients. Several features make the program unique in the United States, said Konrad Hoetzenecker, MD, PhD, professor of Thoracic Surgery and surgical director of the Vanderbilt Lung Transplant Program. Vanderbilt serves as a “second opinion center” and accepts most complex candidates that are turned down by other centers due to increased perioperative risk. This includes patients over 70 years old, patients requiring combined procedures with their transplant, multiorgan transplantations and sensitized patients (individuals who have pre-formed anti-HLA antibodies who are at higher risk for complications). The expertise and excellent outcomes have attracted patients far beyond the borders of Tennessee; almost half of Vanderbilt Health’s lung transplant recipients come from out of state. “Another unique feature is our minimally invasive transplant program,” Hoetzenecker said. “By using distinct surgical instruments and techniques, the incisions can be kept as small as 7 to 8 centimeters, which results in better healing, less pain and faster recovery. “This minimally invasive approach is embedded in an Enhanced Recovery After Surgery (ERAS) protocol, a multimodal, evidence-based perioperative care pathway designed to reduce surgical stress, minimize complications and speed up recovery. Our unique ERAS protocol, by a dedicated interdisciplinary approach, aims to improve recovery after lung transplant and reduce ICU and hospital stay.” The lung transplant program recently celebrated a milestone — 1,000 lung transplants since the program began in 1990. “This significant achievement reflects the concerted effort of a multidisciplinary collaboration by the Departments of Thoracic Surgery, Medicine, Anesthesiology and Critical Care,” said David Erasmus, MD, associate professor of Medicine and medical director of Vanderbilt Lung Transplant. Lung transplants have been attempted since the 1960s, but they were largely unsuccessful until the 1980s, when surgical techniques were refined and new antirejection drugs proved effective. Patient outcomes steadily improved from the 1990s to the present. Vanderbilt’s fourth lung transplant recipient in 1990, Pam Everett, is the longest-living, single-lung transplant known in the world, recently celebrating 35 years since her transplant. The Vanderbilt Lung Transplant surgical team is led by Hoetzenecker and Caitlin Demarest, MD, PhD, the surgical director and associate surgical director of the Vanderbilt Lung Transplant program. Erasmus is the medical director of Vanderbilt Lung Transplant along with Anil Trindade, MD, associate medical director and associate professor of Medicine.

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Mar 27 • 10:12 AM EDT • Health • news.vumc.org
NYC Health + Hospitals/Woodhull Earns National Recognition as Center of Excellence in Surgical Safety - NYC Health + Hospitals

NYC Health + Hospitals/Woodhull today announced it received the Center of Excellence in Surgical Safety: Prevention of Retained Surgical Items (RSI) Award

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Mar 25 • 11:36 AM EDT • Health • nychealthandhospitals.org
NYC Health + Hospitals/Jacobi | North Central Bronx Brings Novel Minimally Invasive Vascular Surgery Procedures to the Bronx - NYC Health + Hospitals

NYC Health + Hospitals/Jacobi | North Central Bronx today announced it has begun offering two types of minimally invasive surgical procedures that were

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Mar 23 • 1:58 PM EDT • Health • nychealthandhospitals.org
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Rochester Regional Health Launches Targeted Loan-Support Program to Strengthen Access to Critical Healthcare Services

Rochester Regional Health (RRH) today announced a targeted student-loan support program designed to strengthen access to essential clinical care across the region. Through a partnership with Clasp, Rochester Regional will help future Certified Registered Nurse Anesthetists (CRNAs), Surgical Technologists, and Radiologic Technologists finance their education and begin their careers serving the patients of Rochester and the Finger Lakes Region.

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Mar 16 • 10:00 AM EDT • Health • finance.yahoo.com
Robotics firm Intuitive Surgical says cyberattack compromised business, customer data

The company said an intruder accessed employee information, customer contact details and other records.

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Mar 16 • 6:17 AM EDT • Business • cybersecuritydive.com
Trinity Health hospital north of Ann Arbor to relocate in April

The public can tour the new 174,000-square-foot facility, test a surgical robot and explore emergency vehicles before the new hospital opens.

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Mar 10 • 2:47 PM EDT • Health • mlive.com
NYC Health + Hospitals/South Brooklyn Health's Medical and Surgical Intensive Care Units Recognized with Silver Beacon Awards for Excellence - NYC Health + Hospitals

NYC Health + Hospitals/South Brooklyn Health today announced that their Medical Intensive Care Unit (MICU) and Surgical Intensive Care Unit (SICU) both

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Mar 6 • 1:50 PM EST • Health • nychealthandhospitals.org
Around the MHS

The latest news from around the Military Health System for the week of March 2-6, 2026, includes a vital collaboration between Department of War and the Department of Veterans Affairs, new whole genome sequencing brain research, and a military surgical milestone.

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Mar 5 • 7:00 AM EST • Health • health.mil