SCROLL NEWS / DISCOVERY
Search headlines
Find the stories shaping the conversation.
Results for " tight " 100 found 🔀 AI-powered Shuffle
Sign in to save shuffle history.
Political science professor shares insight on tight election races
Some people think the GOP is concerned with tight Kansas races after the second visit in October from the federal administration.
Trump Endorses Netanyahu as Best U.S. Partner in Tight Israeli Election
The president praised the embattled prime minister for his endurance, saying any other candidate would be the “wrong Leader.”
Blue shift: Yet another political forecaster shifts CD 25 race in Jared Moskowitz’s favor
‘The race doesn’t appear to have tightened, so we’re shifting it.’
In tight WA House race, sparks fly over safety at challenger’s business
Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.
Steam Pricing Analyst Found Hollow Knight: Silksong's $20 Price Annoying: 'I Was A Bit Like, Oh God, Please Price It Higher'
Indie devs are facing tighter pricing pressures than ever
Hospitals are selling their real estate. The deals may prove costly
Health systems are selling hospital real estate to raise cash for operations and growth, but higher rents and tighter oversight add new pressure.
Michigan GOP Senate nominee Mike Rogers on whether Iran war was a mistake: ‘We’ll find out’
Rogers and Democrat Abdul El-Sayed spoke to “NBC Nightly News” about Iran, the economy and the issues driving the tight Michigan Senate race.
Pols & Politics: Questions raised in recent polling on Gov’s race as RNC survey shows tight matchup
Recent polls on the upcoming race for Massachusetts Governor, which showed double-digit leads for Gov. Maura Healey over GOP challenger Mike Minogue, have raised questions on their methodology.
Week in politics: Vance defends Ohio political ad and Kansas Senate race remains tight
A political advertisement in the Ohio gubernatorial race is being called one of the ugliest of the midterm election cycle.
In tight WA House race, sparks fly over safety at challenger’s business
Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.
Apple enters new product category with HomeView device
If the HomeView takes off, Apple will have tightened its grip on its ecosystem, making it harder to move to a rival like Google or Amazon.
How Small Pharmacy Expansion Will Impact CVS Health (CVS) Investors
CVS Health has been rolling out smaller pharmacy focused stores, expanding MinuteClinic sites and raising its 2026 revenue and earnings outlook, alongside new efforts in benefit transparency and women’s midlife health research. The push into underserved neighborhoods with compact pharmacies and clinics points to a tighter focus on access, operating efficiency and aligning physical sites with where prescription demand actually shows up. This article examines how CVS Health’s investment...
OU's goal remains the same: 'Make the playoffs'
Following the 21-13 loss to No. 12 Kentucky on Saturday night, OU defensive backs Omarion Robinson and Reggie Powers and tight end Hayden Hansen recapped the game.
Report: Northwest Arkansas commercial real estate market remains tight
The Northwest Arkansas commercial real estate market remained tight in the office, industrial and retail sectors in the third quarter as major projects opened and new development broke ground across...
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine
Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria cont...
Santa Rosa massage business in “sticky” situation as planning commission denies certification over illicit advertising
A massage business in Santa Rosa had its appeal for certification denied by the city’s planning commission over an ad found on an illicit website, the latest rejection under tightened rules imposed last year.
Tigers pitcher Troy Melton given clean bill of health entering offseason
Right-hander ended solid 2026 season early because of tightness in his right forearm.
Texas political leaders debate Donald Trump visits as midterm races tighten
RNC Chair Joe Gruters and Texas Democratic Chair Kendall Scudder debate whether repeated Texas visits by Donald Trump and heavy GOP spending signal tight statewide races or routine midterm turnout efforts.
‘They Want to Get Into the Taylor Swift Business’ — Media Analyst ‘Rationalizes’ Travis Kelce Possibly Coming in as Troy Aikman’s ESPN Replacement
Kansas City Chiefs tight end Travis Kelce re-signed with the franchise this offseason, and the Chiefs have come flying out of the blocks to a 4-0 record. Once the current season ends, however, there is some speculation about where Kelce may head next, particularly if it comes to a role in the broadcasting booth.
Colts Activate Tight End from IR Ahead of Titans Matchup
The Indianapolis Colts have activated tight end Will Mallory from Injured Reserve and removed him from the injury report for Sunday's game against the Tennessee Titans.
Suburban women souring on Paxton could doom him in tight race
Interviews with these voters reveal a combination of apathy toward his candidacy and an active shift by some toward his Democratic opponent.
New coalition aims to keep Virginians covered as Medicaid rules tighten
Virginia Secretary of Health and Human Resources Marvin Figueroa on Monday announced the Virginia United Coalition, formalizing a partnership that builds on a series of roundtable meetings with him and Gov. Abigail Spanberger throughout the summer, as well as an executive order she signed.
White House has tight grip over FBI in pursuing Trump targets, agent says
The testimony was the latest account of just how tight a grip the White House has on decision-making at the FBI.
Seeking to help Collins in Maine, Trump exempts some Canadian imports from his 50% tariffs
Collins, locked in a tight race with Democratic challenger Troy Jackson, issued a statement saying she'd spoken with Trump's top trade negotiator, Jamieson Greer, and Commerce Secretary Howard Lutnick "about the toll tariffs are taking on Maine families, businesses, farmers, and growers.''
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine
Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria contracted Ebola.
Business First Bancshares (BFST) Is Back In Focus, What Is The Market Weighing?
Business First Bancshares (BFST) is back in focus after third quarter results topped earnings expectations, accompanied by stronger loan and deposit trends, wider net interest margin, and tighter cost control following the Progressive Bank integration. Business First Bancshares’ latest update has arrived after a year of solid progress, with the share price at $31.82 and a clear shift in sentiment following the earnings beat, active buybacks, and fresh common and preferred dividend...
Where to Buy iPhone Duo Today: Stores, Pickup, and Wait Times
Apple's first foldable iPhone, the iPhone Duo, officially launched today, Friday October 23. Pre-order deliveries are arriving to customers, but supply is extremely tight, although anyone who didn't order in advance may still be able to buy one in person, depending on local availability. That said, Apple has said it expects supply to sell out quickly.
Former Buccaneers tight end Devin Culp signs with Browns
Former Buccaneers tight end Devin Culp has signed with the Cleveland Browns' practice squad after being released by Tampa Bay in September.
Amex Platinum and Business Platinum add Airbnb perks, but lodging credit rules are tightening
American Express adds Airbnb bookings and new benefits for Platinum and Business Platinum cardmembers, alongside tightening rules for a popular lodging credit.
Travis Kelce Is Doing Something Remarkable at 37 Years Old
Travis Kelce turned 37 on October 5th, and usually, that's about the time an NFL tight end starts thinking about life after football. Kelce's numbers suggest he's got other plans. Through four games, the Kansas City Chiefs veteran is averaging more yards per catch than he has in years, and Patrick Mahomes is still finding …
In tight Texas Senate race, Trump's immigration crackdown tests Republicans' hold on voters
The race between Democrat James Talarico and Republican Ken Paxton is hotly contested and enormously expensive, with total ad spending topping $500 million.
Chiefs Announce Historic Travis Kelce News During Seahawks Game
Kansas City Chiefs tight end Travis Kelce can’t stop making NFL history.With his third reception in the fourth quarter against the Seattle Seahawks on Sunday night, Kelce has passed Hall of Famer Tony Gonzalez for the most receiving yards by a tight end ever, including the postseason, with 13,342.Kansas City Chiefs’ Travis Kelce is Most […] The post Chiefs Announce Historic Travis Kelce News During Seahawks Game appeared first on HEAVY.
T.J. Hockenson finds end zone in Week 7 vs. Colts
Minnesota Vikings tight end T.J. Hockenson posted four receptions for 35 yards and a touchdown on five targets in Week 7
Analysis | Home heating oil is a sleeper campaign issue across cold-weather battlegrounds
As the weather grows cold in key battlegrounds nationwide, sky-high home heating oil prices could tilt a series of tight races.
Trump’s Overtures to Putin Put Republican Candidates in Hot Seat
GOP politicians in a number of tight races are breaking with Trump on Russia policy ahead of midterms.
Broncos select Oregon tight end in 2027 NFL mock draft
The Broncos land Oregon's tight end in this 2027 NFL mock draft.
Trump ramps up attacks on Dems in tight races
President Trump is intensifying personal and Islamophobic attacks on Democratic candidates in several states as Republicans worry about a voter-enthusiasm gap ahead of the November 3 elections. CNN’s Alayna Treene reports from a rally in Northern Kentucky.
GOP states have made it harder to vote. The changes could swing tight races
GOP lawmakers and officials around the country have enacted voting restrictions that could affect turnout in key races.
State of Texas: Tight races test voters, parties and a new political map
The race for U.S. Senate is the biggest story in Texas politics, and it’s getting nationwide attention. Campaign spending between Ken Paxton and James Talarico is on pace to set records, and …
Clemson lands second commitment in 2028 recruiting class
The Clemson Tigers have landed a commitment from 2028 tight end Wright Martin. He is their second commit in the 2028 cycle.
Rams TE Terrance Ferguson's Return Will 'Take Some Time'
The Los Angeles Rams may be without another player, as tight end Terrance Ferguson is a ways from still returning.
Week 8 fantasy tight end rankings: Top TE streamers, starts
After a painfully slow start, the Bears' Colston Loveland has rebounded to post consecutive top-6 tight end performances. He's in line for another.
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
A procrastinator’s guide to NH’s 1st Congressional District
This race is tight, and the result could have huge impacts.
Georgia Republicans are trying to court Latino voters. National politics are complicating things.
In a battleground state with tightening margins, Georgia’s Latino voters have the potential to affect the outcome of the governor’s race in November.
In one of the West's few swing races, a Democrat tries to keep a Trump district
Washington’s 3rd Congressional District is home to a tight race that will help determine the balance of power in the U.S. House.
Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain
Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)
Republican billionaire Rick Jackson is walking a Trump tightrope in his quest to lead Georgia
Jackson’s path differs from Donald Trump’s, and the 72-year-old healthcare magnate and investor brings a vastly different persona to his first campaign. Unlike Trump, who was born to wealth, Jackson spent his early years bouncing through foster homes before launching his first company as a young man.
5 Pocket-Sized EDC for People Who Hate Carrying Bulky Multitools
A multitool can earn its place in your pocket, right up until its weight makes you leave it at home. Pliers, blades, drivers, and openers all need somewhere to go, and those stacked layers of steel add up. If your daily repairs mostly involve opening a package or tightening a loose screw, carrying the entire
Cam Grandy headed back to Cincinnati
The Cincinnati Bengals are signing tight end Cam Grandy off the practice squad of the Minnesota Vikings
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Eagles to release E.J. Jenkins ahead of Cowboys matchup
The Eagles are releasing E.J. Jenkins, according to Mike Garafolo. The tight end appeared in all six games this season, making two starts
Former Buccaneers Draft Pick Signs With Browns
When the Tampa Bay Buccaneers waived their former seventh-round pick, Devin Culp, before his third NFL season, he cleared waivers and did not find a new team right out of the gate. However, before the Cleveland Browns‘ Week 6 matchup against the Baltimore Ravens, the team decided to sign the Bucs’ former tight end to their […] The post Former Buccaneers Draft Pick Signs With Browns appeared first on HEAVY.
Political science professor shares insight on tight election races
Some people think the GOP is concerned with tight Kansas races after the second visit in October from the federal administration.
What Dueling Visits by Ocasio-Cortez and Manchin Say About Maine’s Senate Race
Senator Susan Collins, a Republican in a tight race, is keying her closing pitch to the middle, while her progressive challenger, Troy Jackson, is seeking to excite the left.
The real reasons US politicians are getting older
No country for young men and women: why do older politicians seem to have such a tight grip on the US political system?
As Florida governor’s race tightens, Ken Griffin gives another $5 million to Donalds
Ken Griffin said: “The people of Florida deserve leaders who wake up every day thinking about how to make their lives better.”
Seahawks swap practice squad tight ends, sign Ben Sims
It’s one in, one out at tight end to start Week 8 for the Seahawks.
Republican billionaire Rick Jackson is walking a Trump tightrope in his quest to lead Georgia
Rick Jackson wants to be Georgia's governor and the Republican billionaire is promising to fight for working-class voters.
Report: Bears Fear Cole Kmet’s Knee Injury Is Season-Ending
A reported knee injury has the Bears bracing to lose their top blocking tight end. #OnePride
Is Eli Stowers playing Monday? Latest Eagles injury update
Eli Stowers is listed as questionable against Dallas after a full practice week as the rookie tight end works back from a quadriceps injury
After a rash of burglaries at South Side establishments, Black business owners are wondering: ‘Why us?”
Business owners are coming together and demanding tighter security after a rash of burglaries targeting Black-owned businesses on Chicago’s South Side.
On Byron Donalds campaign stop in Sarasota, crowd cheers for keeping Florida red
Polls show Donalds in the lead, though it's a tight race with 12 days to go until the election.
Marie Gluesenkamp Perez vs. John Braun: Two styles of lawmaking
U.S. Rep. Marie Gluesenkamp Perez and state Sen. John Braun face off in Washington's 3rd, bringing contrasting styles of lawmaking, coalition-building and problem-solving to a tight race.
Apple's new hardware strategy capitalizes on trust — just in time for the AI era
Apple's smart home strategy is about selling more hardware. But it's also about more tightly binding iPhone customers to its ecosystem.
How to Manage Symptoms of Heart Failure
(Feature Impact) Americans are facing a growing health challenge, with 1 in 4 adults at risk of heart failure, according to the Heart Failure Society of America. Additionally, approximately 6.7 million U.S. adults who are 20 years old or older are currently living with heart failure, and that number is projected to reach 8.7 million by 2030. googletag.cmd.push(function() { googletag.display('JGFI_Article_300x250'); }); Managing heart failure is a significant expense to the U.S. healthcare system, costing the nation approximately $40 billion in 2020 and expected to increase to approximately $142 billion a year by 2050.If you (or a loved one) are living with the condition, consider these tips to help manage it.Adhere to the Treatment and Follow-Up PlanOngoing outpatient care is important when managing heart failure. Understand the treatment plan provided by your healthcare team, make diet and lifestyle changes, take medications as directed and keep recommended follow-up appointments.Pay attention to changes in symptoms and communicate with your healthcare provider if treatment does not seem to be working as expected. If their conditions are left unmanaged, patients can experience a range of heart-failure-related symptoms such as shortness of breath, fatigue, buildup of fluid and more.Understand Challenges with Diuretic TreatmentDiuretics help the body remove excess fluid and are commonly used to treat swelling, or edema, associated with heart failure. Your provider may try different diuretics, sometimes referred to as “water pills,” to manage your heart failure symptoms. However, intravenous (IV) diuretic therapy may be required for some patients if symptoms continue.Ask About Treatment Options Before IV Care Is NeededFor some adults, a healthcare provider may consider recommending an at-home, non-oral diuretic option prior to escalating to IV therapy.For example, ENBUMYST™ (bumetanide nasal spray) is a prescription diuretic used in adults to treat edema associated with congestive heart failure. It’s administered as a nasal spray for short-term use to manage excess fluid with the goal of transitioning to oral diuretic therapy when appropriate.Talk with your healthcare provider to learn more and visit enbumyst.com. Read the full Prescribing Information and Patient Information.Photo courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('JGFI_Article2_300x250'); }); Important Safety InformationWhat is ENBUMYST?ENBUMYST is a prescription medicine used in adults to treat swelling caused by excess fluid in the body (edema) from congestive heart failure, liver disease, and kidney disease.What is the most important information I should know about ENBUMYST?ENBUMYST is a diuretic that helps your body remove fluid. Losing too much fluid can cause dehydration, low blood volume, and increase the risk of blood clots. Blood abnormalities may include decreased salts (electrolytes), and increased nitrogen, glucose and uric acid. The risk of these abnormalities is higher in elderly people, those using higher doses, or those who do not get enough electrolytes by mouth.You should not use ENBUMYST if you have severe electrolyte loss. Tell your healthcare provider if you experience unusual thirst; dizziness or lightheadedness; weakness or tiredness; fast heart rate; dry mouth or tongue; sudden pain; redness or swelling in your joints; pain, swelling, redness, or warmth in your leg; shortness of breath or fast breathing; high blood sugar; dark urine; pale, tight, cool or clammy skin; muscle cramps; confusion.Do not use ENBUMYST if you have low or no urine production or are allergic to bumetanide or to any of the ingredients in ENBUMYST.Before using ENBUMYST, tell your healthcare provider if you have low electrolytes, are on a low-salt diet, have diarrhea, diabetes, nasal problems such as a runny or stuffy nose or polyps, a history of nasal injury or surgery, are or plan to become pregnant, are or plan to breastfeed.Tell your healthcare provider about all the medicines you take, including prescriptions, over-the-counter medicines, vitamins, and herbal supplements.ENBUMYST may cause serious side effects, such as worsening kidney function and ringing in the ears or hearing loss.The most common side effects of ENBUMYST include dehydration, headache, muscle cramps, dizziness, low blood pressure, nausea, and abnormal brain functioning with certain liver problems.These are not all the possible side effects of ENBUMYST. Talk to your healthcare provider for more information.Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.US-ENBU-2600110 googletag.cmd.push(function() { googletag.display('JGFI_Article3_300x250'); });
Can AI solve our mental health access problem?
Last week I asked you what worries you most about AI in health. It was close, but your top answer was “AI giving bad health advice.” Last week’s poll results: You’re in good company. This concern was top of mind at a conference I joined at Stanford last week, where researchers, clinicians, and people who build AI systems spent a day debating trust and safety in health AI. Stepping back, I’m also hearing your emerging concerns about AI’s impact on our well-being generally. I see this as a matter of public health, and we’ll take it in pieces as we learn together. Today we’ll focus on AI chatbots used for therapy for mental health. Early this month, Governor Newsom vetoed Senate Bill 903, California’s most ambitious attempt to regulate AI use for mental health. It’s at the center of active debate, and raises the questions patients, family members, citizens, and voters will face as AI moves deeper into health care. Let’s work through it. What is “AI-based therapy”? It’s really two things: purpose-built mental health apps designed to deliver structured support, and general chatbots like ChatGPT, Claude, and Gemini that people increasingly use for emotional support—even if they weren’t built for it. Spoiler alert: I don’t know whether the shift toward AI therapy is good or bad. The evidence isn’t there yet. But I do know it’s already happening, and I have some ideas about how we can roll it out with safety in mind. The therapy dilemma, in a nutshell Mental health challenges are common, and strain health and well-being across populations. Therapy (interactive dialogue with a trained, empathetic practitioner) helps many people heal. The demand for licensed therapists far exceeds the supply in California, and AI-based therapy can narrow that gap. AI-based therapy remains novel, unproven, and not well tested. Right off the bat, we can see we’re dealing with trade-offs here. Since the main driver of demand for therapy from a robot is lack of access to therapy from a human, we’ll start there. It’s too hard to find and afford a human therapist California is short roughly 55,000 licensed, non-prescribing therapists and counselors, about 40% of what we need. Psychiatrists, who rely on talk therapy as a complement to prescribed medications, are even more scarce. Eight counties have none, and density ranges from 1.7 per 100,000 residents in San Benito County, to 68.1 in Marin County. My wife is a psychiatrist in Marin, and even here access is tight. If it’s hard in the best-supplied county, imagine rural Sierra County, or the San Joaquin Valley. In 2024, more than half of Californians who tried to make a mental health appointment struggled to find a provider who took their insurance, compared with 14% for physical health care. When Senate staff posed as “secret shopper” patients and called 120 mental health providers in Medicare Advantage networks, they landed an appointment less than once for every five tries. Insurers pay behavioral health clinicians about 22% less than medical and surgical clinicians for comparable office visits. On top of that, billing denials and prior authorizations hit hardest at the solo and small practices common in mental health. Psychiatrists opt out of Medicare at the highest rate of any specialty. In many places, a cash practice for therapy fills quickly with patients paying $250 or more an hour, with no insurance paperwork at all. Families who can pay cash find providers more easily. Those who rely on insurance, including Medi-Cal enrollees, older adults, rural residents, and non-English speakers, compete for what’s left. So we can’t pretend the human system works, and we can’t blame people for turning to AI for support when they’re in distress. AI is filling the gap It’s estimated that roughly a quarter of AI users use it for mental health support. If you have internet, it’s available 24/7, it’s cheap, and it speaks your language. Uninsured adults are about twice as likely as insured adults to do it (30% vs. 14%). It feels anonymous in ways that may enable people to ask things they’re unsure or embarrassed about. The largely hidden, personal use makes it hard to study whether it’s actually helping people with their mental health issues, but researchers are trying. Does AI therapy work? A 2026 analysis of nearly 40 randomized trials found chatbots showed a real but small reduction in depression symptoms. But most of these trials were compared to an alternative of no therapy, not a human therapist. So the benefit of AI therapy is probably real, but modest, and mostly untested against the alternative of human contact. We need more studies. Serious concerns OpenAI’s own estimate is that more than a million ChatGPT users each week show signs of suicidal planning or intent. These are high stakes encounters, and AI doesn’t always get it right. That’s partly because a chatbot can sound like a therapist, but it has no license, no duty of care, and it’s not clear who to hold accountable when it gets things wrong. AI is also designed to help users in whatever task they’re seeking to accomplish. People may feel like they’re getting therapy, but they’re mainly getting a convincing conversation. It’s easy for an AI companion to wander into gray areas, like playing along with “creative writing” that may be about the user’s own suicidal intent. Courts are driving safety conversations A wave of lawsuits have been filed on behalf of families claiming that chatbots pushed people they loved toward self-harm, including teens who died by suicide. The first settlements came this year. OpenAI is headquartered in San Francisco, and dozens of cases alleging that ChatGPT drove users to suicide or self-harm are now before a San Francisco judge. Character.ai has filed for bankruptcy after several states brought lawsuits accusing the chatbot of pushing dangerous content to kids. But the technology seems to be improving. Last month, an independent evaluation found that newer AI models “almost never endorse suicide.” That’s progress, but our societal appetite for even one preventable death is very low. So how do we move forward? Finding a middle ground Earlier this month the governor vetoed Senate Bill 903, a bill designed to place guardrails on the use of AI for therapy. The bill would have prohibited any AI-based platform from being advertised as psychotherapy, and would have required a licensed professional to review and approve each encounter where AI was used to support therapeutic decisions. Newsom called it overly broad, since even routine screening questions would have needed clinician sign-off. Knowing we’re already short on mental health providers, requiring human review of AI encounters may not relieve our access problems. Still, the answer isn’t no oversight. Here’s one feasible short term solution. Rather than reviewing each encounter, a licensed clinician can design the guardrails: what counts as a crisis, what triggers an immediate handoff to a human, and what gets sampled for audit each month. The AI runs inside that structure. Conversations get checked, failures get reported, and a real clinician owns the framework. Medicine already has models to learn from. The FDA process for rolling out newly approved medications is an example. After a product reaches patients, we keep watching for adverse events. Patient-facing AI needs the same “digital pharmacovigilance”: systematic tracking of harms, near misses, and the types of groups that get hurt and why. It’s also critical that users know that they can reach a human if they’re in crisis. Most chatbots now include messages like these: Bottom line The rush to use unproven AI tools for mental health support is mostly a workaround, a sign of a health system people can’t get into. We need better access to proven care from licensed clinicians. That takes reimbursement that makes accepting insurance viable, and a bigger workforce. But, built and tested well, AI could be part of the answer. It could be the 2 a.m. check-in when no one else is awake, or a way for patients to practice skills their therapist taught them. It could be the first step to get someone the right level of care, and take paperwork off clinicians’ plates so they spend more time with patients. None of this is simple. The SB 903 veto doesn’t end the debate, and the legislature will be back. In the meantime, those of us using these tools need to stay informed, ask hard questions, and hold the companies building them accountable. I’ll try to do my part, and we’ll keep learning together. Love,Matt P.S. If you or someone you know is struggling with mental health challenges, emotional distress, substance use problems, or just needs to talk, call or text 988- you’ll reach a real person— or chat at 988lifeline.org 24/7. Dr. Matt Willis is the author of Your Local Epidemiologist in California. A California native, he’s served as a primary care physician, CDC epidemiologist, and public health officer for Marin County, where he guided the pandemic response. He lives in Marin with his family and their dogs, Teddy and Ramona. Thank you Cynthia He, MD, PhD, and Parnika Saxena, MD, for their guidance in preparing this article. Cynthia works in an outpatient mental health clinic, treating patients who have Medi-Cal or, sometimes, no insurance. Parnika works in an inpatient psychiatric unit, treating patients with public or private insurance or self-pay ability. All opinions are their own and do not represent their employers.
Tucker Kraft scores TD in Week 7 vs. Lions
Green Bay Packers tight end Tucker Kraft finished with four receptions for 48 yards and a touchdown on six targets in Week 7
200 supporters rally for Hinojosa as Abbott is expected to campaign in Houston-area this week
Democratic candidate for governor Gina Hinojosa rallies with supporters the day before the state of early voting. The race has tightened in recent weeks. Governor Greg Abbott is also expected to spend time in the southeast Texas this week.
The political stunner of Frank White’s ascension in Arkansas
With the governor's race tightening and Gov. Sarah Sanders making every political mistake in the book, it seems like a good time to revisit the shocking Arkansas governor's race of 1980.
Roger Marshall praises Trump's tariff policies after Kansas executive says they hurt his business
U.S. Sen. Roger Marshall, locked in tight campaign with Democrat Adam Hamilton, throws full support behind President Donald Trump's tariff war.
Isaiah Likely disappoints in Week 7 vs. Texans
New York Giants tight end Isaiah Likely limited to two receptions for 12 yards on four targets in Week 7
Seahawks injury update: Elijah Arroyo’s season is over
The Seahawks tight end will end his sophomore campaign with only one catch.
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Election day is soon, and the race for Colorado's Fifth Congressional District is tight.
Brazil's runoff: Lula's legacy vs. Bolsonaro's dynasty
Brazil's tight presidential runoff pits a political giant against a Bolsonaro heir in a battle over the country's political future.
SPECIAL REPORT: Tough Business
A string of vacant restaurant buildings shows that many restaurants in the region are struggling — and several are closing By Stefan Yablonski [caption id=attachment_11132 align=alignright width=401] Smokey Bones Bar & Fire Grill on Route 31 in Clay closed its doors in April. It had been in operation since at least 2008.[/caption] By their nature, most restaurants have a limited life. An astonishing 60% go out of business within three years of opening, largely due to fundamental flaws in the planning of the operation. But even restaurants that experience years of success almost always face eventual closure. The restaurant business is very hard and because of both personal factors and external factors beyond anyone’s control, restaurants don’t last forever. For many restaurants, age is a big factor, according to Kenneth Walsleben, professor of practice, entrepreneurship and emerging enterprises at Syracuse University. “The owners have been at it for 20 or 25 years, if not longer, they want some time to themselves,” he said. Such was the case for Jocko’s Famous Ritz Diner in Oswego. Jocko Reitz bought the building in the late 1970s from Robert Shapiro. However, when he stepped away from the business, it eventually closed. [caption id=attachment_11142 align=alignright width=402] For nearly 80 years, Vona’s Restaurant passed through three generations of family in Oswego. It closed its doors on Dec. 31, 2025.[/caption] For nearly 80 years, Vona’s passed through three generations of family in Oswego. Vona’s Restaurant officially closed its doors on Dec. 31, 2025, when no family member wanted to take over. It is on the market. The Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026. The restaurant faced multiple temporary health department closures in 2024 and 2025 due to persistent fruit fly and foundation pest issues. Management posted a final closure notice on the doors in mid-April 2026 and the building was put up for sale. The same pattern has been happening in Onondaga County. The big building once used by Smokey Bones Bar & Fire Grill on Route 31 in Clay remains empty, more than six months after the restaurant closed its doors in April. It had been in operation since at least 2008. [caption id=attachment_11130 align=alignright width=401] Ruby Tuesday in Oswego operated for about two decades before permanently closing in April 2026.[/caption] Just down the road from Smokey Bones, the popular Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty. Other very popular restaurants in the northern suburbs of Syracuse have recently closed. Among them, Fireside by the River in Baldwinsville and Primo Nestico’s Bistro Bar in North Syracuse. “I haven’t really paid attention to the Syracuse area. There has always been some turnover, but there probably has never been a tougher time to be a restauranter than now. It’s just brutal,” Walsleben said. In the first year, roughly 20% to 25% of restaurants close or change hands, according to the National Restaurant Association. [caption id=attachment_11122 align=alignright width=401] Outback Steakhouse closed in August 2024. Another restaurant took its place, La Cocina Mexican Restaurant, but it closed shortly after. The building sits empty.[/caption] “Depending on what statistics you look at, you’ll find that any business has a high mortality rate in the first year. That is just the nature of entrepreneurship,” Walsleben said. “There are certain ones that are getting hit hard while others are more fruitful. “And when you look at the restaurant industry you have to factor in labor which is a large part — typically a third of your expenses — and those costs are going up. And there is always turnover which means investing money to train people. Then you’ve got food costs, which is also a third of the typical restaurant budget. Since the pandemic labor has gone up 41%, food costs have gone up 35%. That’s a big tight squeeze righty there. That’s two-thirds of your budget that has gone up 35% to 40% in the last few years. And then the only way you can make that work is to raise the prices.” The National Restaurant Association reports menu prices are up 36% since February of 2020. In a survey released by the association, more than eight in 10 restaurant owners reported that their food, beverage and labor costs are now higher than before the pandemic. You have to deal with the reality of are the customers willing to pay for that? Walsleben added. Restaurants historically have very thin margins; their profit margin is about 5%. “You have a third that goes into food, a third that goes into labor and about 28%, 29% that goes into everything else — overhead, insurance etc. So that brings you down to your 5% leftover,” he said. “Everything is going up. Customer expectations are going up and people aren’t going to spend that much more. So, you have a tight squeeze here,” Walsleben continued. “Restaurants who use delivery apps, they pay a fee to those guys. Those guys don’t work for free. So, you can kind of see where the squeeze comes from.” Stuck in the middle There are pockets of opportunity; the two extremes of the market can make a profit. But the middle gets squeezed out. “If you are a low-end fast-food kind of place, there is room for that. People have changed their budgets. They are still going out, but they are not spending more,” according to Walsleben. “The high end remains positive. If you have a restaurant that brings a specific experience … a great food product or you are catering to high end customers who aren’t so budget conscious, those patrons are going to expect a high-end experience. They expect excellent food every time. They are expecting excellent service. If you can meet those expectations there is room for you at the top. It’s just the guys in the middle are getting the squeeze from both ends. Tough competition, customer expectations, costs are up. Menu items, you can’t raise the prices as much as you need to. That is why you are seeing a lot of restaurants baling out.” The ones that can adapt quickly are the ones who are doing OK. “Success is heavily dependent on the strength of a restaurant’s concept development and the planning of its execution. Eventually things aren’t always new. Things change. So, if you are in the restaurant business you have got to change your menu — keep things new, fresh and update your meals. It is very fickle industry. One year carbs are out, the next year berries are out. Everybody’s diet changes — constantly chasing the latest phase. You have got to adjust your menu and move with those modifications. If you have a static menu that you have used the last couple years that hasn’t changed except for the pricing, you’ve got a problem,” he said. A lot of times these buildings are singular purpose, he added. “You have a commercially viable kitchen and you got a seating area. There is not a lot of other businesses that cater to that type of a layout. So, it’s pretty common to see another restaurant slide in,” he said. One of the things a banker learns early on is you don’t lend money to restaurants … because they fail so quickly. It is very hard to predict who the winners will be. So, if you are a restaurant in addition to all the other challenges, it is very difficult to get loans, according to Walsleben. “You might work really well in the kitchen. But that doesn’t mean you are a great businessperson,” he said. “Restaurants can fail because the owner didn’t know how to manage things properly. There are a lot of challenges. “There is opportunity at the high end and the low end. But in the middle, that’s the death valley. There are just so many things working against you. You really need to have something that will pull people in and continue to pull people in because you to constantly have to change. Think about a theme and a product that is unique to the area people don’t travel that far these days you have to be able to deliver it in an innovative fashion and keep updating to keep people coming in the door.” Out of Business? How Fast? Do nine out of 10 restaurants fail in their first year, as commonly claimed? No. Survival analysis of 1.9 million longitudinal microdata for 81,000 full-service restaurants in a 20-year U.S. Bureau of Labor Statistics non public census of business establishments in the western US shows that only 17% of independently owned full-service restaurant startups failed in their first year, compared with 19% for all other service-providing startups, according to ResearchGate. The median lifespan of restaurants is about 4.5 years, slightly longer than that of other service businesses (4.25 years). However, the median lifespan of a restaurant startup with 5 or fewer employees is 3.75 years, slightly shorter than that of other service businesses of the same startup size (4.0 years). What Makes a Restaurant Successful? Opening and maintaining a successful restaurant is not as easy as creating a great menu and serving excellent food. It takes more than that, according to local restaurant owners who have been in business for decades in the region. They all agree that there are some guidelines to running a successful restaurant. • Quality food: Successful restaurants know exactly what they serve and who they serve it to. Delivering the same great taste every single time builds loyal customers. • Smooth operations: Friendly greetings and attentive staff make guests feel welcome from the moment they walk in. Hiring staff for personality and training for skill ensures reliable, caring service. • Smart marketing: Exceptional food and experiences naturally get people talking and sharing online. Word of mouth can help entice customers. Consistent social media and targeted advertising brings in new and repeat guests also. The menu is what keeps patrons coming back to Mimi’s Diner in Fulton, located at 201 N. Second St. “We locally source our produce and our meats. Our chicken and biscuits is a popular, popular special,” said Richard Tagliareni, the third-generation owner and general manager. “It’s all homemade. We have consistently served quality food.” His grandfather started the business more than 55 years ago. Mimi’s is engrained in the community. They cater to the community and are very involved in everything from the schools to local events. The first Mimi’s Drive-In opened in Mexico. Then a second in Oswego and then Fulton. Fulton’s Mimi’s is the only one left. “The last couple of weeks have been kind of slower than normal. October is usually a busier month for us People will start coming back around again. Also, the price of gas is affecting some things,” Tagliareni added. “We try to keep our prices in line. You go out to eat, you’re going to spend about a hundred bucks or so for two people for dinner. You come here to Mimi’s you are probably for two people for dinner it’s between $50 and $60. We are trying to keep our prices in line. We did have to increase our prices a little bit but things are looking OK.” For the Press Box, 29 E. First St., Oswego, it’s also about great food and a family atmosphere. “Our sports bar and restaurant was established in 1984,” said Alison Canale Scanlon, manager. “I think putting the time into everything makes a big difference and treating people like family when they walk into your restaurant. That’s how we have always operated since 1984.” “It’s the family oriented aspect,” she added. “Consistency, quality and presentation of our food — that’s the secret to a successful restaurant. We try to be very consistent with it. We treat people like family when they come in; because we know how we want to be treated when we go to a restaurant. We treat people the same or better.”
Businesses could be barred from non-essential water use amid supply threat
Golf clubs, private schools and car washes may face tighter rules from water companies as England’s drought continues
Ben Johnson Confirms Cole Kmet’s Knee Diagnosis
Cole Kmet's knee got its diagnosis Friday, and Chicago's tight end room looks different now. #NFL
China's big political meeting could see Xi 'tighten discipline' in Party
The highly secretive four-day Plenum starts Monday in Beijing.
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Jeff Crank and Jessica Killin share latest on campaigns, political analyst weighs in on tight race
Kenyon Sadiq still in concussion protocol
New York Jets tight end Kenyon Sadiq remains in the concussion protocol after leaving the Week 5 game
When 1 + 1 = 1: The Miserable Math Behind Many Media Mergers
(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) The last few issues of this newsletter have circled two topics: September’s streaming viewership and all the Paramount/Skydance/Warner Bros./Discovery merger news. I’m happy to say on the Streaming Ratings Report front, we’ll be all caught up by early next week, then the SRR will come out on a tight weekly schedule. Then, after today, I’ll have slayed my PSWbD dragon. It’s such a big story, it demanded multiple issues. With the announcement of a name (just Skydance) and executive team, though, I think we can almost close the book on this story. In terms of topics, it becomes just another studio to cover. So today, I have one last set of takes on that merger. As I’ve sat with it, reading about who was staying and who was going, a big worry crystallized in my brain, and I gotta get that take out. Plus, I still owe you a host of “ugliness” that didn’t fit in my previous “The Good, The Bad and The Ugly” takes. Let’s dive in! Subscribe Most Important Story of the Week - As Paramount Shuffles Deck Chairs, Will They Build or Consolidate? On social media—I try to avoid most social media platforms, but sometimes I end up checking in—the best joke I saw about the announcement of the new name of Skydance was from fellow reporter Claire Atkinson who pointed out… Yeah, I laughed out loud at that one. Later, though, I saw another Twitter response (that later got deleted, so I can’t shout the person out) that did give me pause. The person noted that the Titanic film made the better analogy: a super expensive project everyone in the town doubted that went on to conquer the globe. So yeah: on one hand, the image of the Titanic recalls the actual ship and its infamous end, but that clip is from a movie which proved the doubters wrong. So for all the skepticism of the latest massive media merger, one could wonder which way this one goes. Does it crash like the Titanic or rise to glory like Titanic, the movie? Either way, this deal is “Titanic”, looking at the massive debt required to close the deal, which is not going well when it comes to borrowing costs for Paramount… …or borrowing costs for Oracle. But I’ve started to get worried about another outcome: the sum of this merger will be smaller and weaker and less profitable than its former parts. In other words, one plus one won’t equal three or two, but an even smaller number. Skydance paid to take a traditional studio off the board, but they won’t really capture the upside. Let me explain what I mean, but first, let’s look at the series of news that inspired this thought. Skydance Sets Its Leadership Team As soon as the Paramount-Skydance-Warner Bros.-Discovery merger closed, the new leadership team announced a new name—Skydance, which I’ll use going forward—and a new executive leadership team. You’ve probably read through all the executive shuffling, but if you haven’t, here’s a quick, incomplete summary, in rough order of importance: Mattel’s CEO Ynon Kreiz—who previously ran Maker Studios—joined as co-CEO with David Ellison. HBO/HBO Max’s Casey Bloys will stay and run streaming. Former head of streaming for Paramount-Skydance Cindy Holland—who was also at Netflix—will depart. The former heads of Warner Bros.—Pam Abdy and Mike De Luca—are out. The film studios will be run by Dana Goldstein and Josh Greenstein. George Cheeks of Paramount will run Skydance TV, controlling all the TV production units. In comic book news, the DC films will still be run by Peter Gunn and Peter Safran. Lastly, the head of CNN, Mark Thompson, will stay in place. Let’s quickly opine on the particulars before diving into the broad ramifications. We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… Who I like and dislike in their next gigs… Why I think this consolidation will likely leave Skydance worse off… The math behind which mergers succeed and which don’t… A lot more ugliness in this merger… And a whole lot more... ...please subscribe! We can only keep doing this great work with your support.
White House Has Tight Grip Over FBI in Pursuing Trump Targets, Agent Says
In court testimony, the agent outlined the willingness of Kash Patel, the F.B.I. director, to take orders from President Trump to investigate his perceived enemies.
Trump uses antisemitic slur to defend GOP Kansas senator
GOP Kansas Sen. Roger Marshall Marshall is locked in an unexpectedly tight reelection battle against Democrat Adam Hamilton in what might be the biggest surprise of the midterms.
New PS5 Update Is Out Now, And Sony May Be Tightening Security Before GTA 6
Is there more to this new PS5 firmware update than just improved stability?
Michigan Senate Candidates Make Dueling Pitches to Business Leaders in Detroit
Mike Rogers and Dr. Abdul El-Sayed, the candidates in the tight race, defended their economic policies at the Detroit Economic Club.
Spotify introduces QR code checks for Family plans, missing verification could mean a year-long ban
Spotify is tightening household checks for its Premium Family plan with time-sensitive QR codes, and members who miss the seven-day verification window could face a 12-month restriction on joining another Family plan.
Scientists discover cell division does more than make new cells: It helps reshape tissues
Every time a tissue grows or renews itself, cells must divide inside an already crowded environment. That creates a fundamental problem that scientists have not fully understood: How does a tightly packed ...
NVIDIA Denies RTX 5090 Discontinuation Rumors, Admits Supply Is Tight
NVIDIA has finally responded to reports that the GeForce RTX 5090 is being discontinued. Jeff Fisher, senior vice president of NVIDIA's personal computing business, told Taiwanese media after the RTX Spark launch party in Taipei on October 16 that the rumors aren't true, as reported by 4Gamers...
State of Texas: Tight races test voters, parties and a new political map
The race for U.S. Senate is the biggest story in Texas politics, and it's getting nationwide attention. Campaign spending between Ken Paxton and James Talarico is on pace to set records, and the race ...
This Trade For A Tight End Could Energize Denver's Offense
The Denver Broncos need to add to their offense, and a trade for this Eagles tight end could help.
Political experts call the Georgia governor race 'stuck in molasses'
Republican Rick Jackson holds a tight 49% to 47% lead over Democrat Keisha Lance Bottoms in a new Georgia governor poll.
Dalton Schultz totals five receptions in Week 7
Houston Texans tight end Dalton Schultz posted team highs with five receptions, 45 yards and six targets in Week 7