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Eli Lilly breaks ground on $5B Virginia manufacturing site
Eli Lilly ceremonially broke ground on its $5 billion Goochland County manufacturing facility Thursday, expected to begin production in 2030.
Can we really live forever? The tech, science and ethics behind chasing immortality
From gene editing to cryonics to uploading our brains to the cloud, here are the ways we might one day live forever
Buffalo Council Considers Offers on Properties at Business Park
Buffalo’s City Council considered two offers on properties in the Buffalo Business Park. The first was for Block 1, Lot 1 with a counter-offer with minor changes recommended to the agreement. The council approved the counter offer. The second offer was for Block 2, Lot 2 in the Business Park. Councilwoman Myra Camino made a […]
From Animal Camouflage to AI: The Evolving Science of Staying Unseen
Nature’s game of hide and seek is entering the age of intelligent machines. A new article in National Science Review traces how animal camouflage, advanced materials and artificial intelligence are converging to reshape the contest between detecting an object and keeping it concealed.
The subtle ways a lack of vitamin D affects you
As winter approaches in the northern hemisphere and the days get darker, our bodies are suffering more than we realise. We need sunlight on our skin to produce the vital vitamin D, which is important for bone and muscle health and immune function, but there’s just not enough strength in the sun at this time of year to do it.
Business News: LVMH-Owned Zenith Is Restructuring In Major Reset As Brand Plans Job Cuts And Production Drop In Shift To High-End Market
Up to half of the employees at Le Locle manufacture could lose their jobs as the brand cuts models and production in restructuring after years of financial losses.
Business activity expands, prices surge by most since 2022
Supplier delivery times lengthened the most since 2022, with S&P Global citing material and labor shortages as well as overloaded suppliers and shipping delays.
In New Mexico governor’s race, Deb Haaland’s historic bid tests Democrats' political hold
If Deb Haaland wins New Mexico’s race for governor, she’ll make history as the first Native American woman to lead a state.
AFL Releases FY2025 Corporate Responsibility Report
AFL, the Duncan, South Carolina-headquartered manufacturer of fiber optic cable, equipment, accessories, and related services, released its FY2025 Corporate Responsibility Report. As a reflection of AFL’s continued commitment to creating long-term...
‘Expendable’ Buffalo Bills WR Named NFL’s Top Trade Candidate
"Expendable" $30 million Bills WR called NFL's top trade candidate. The post ‘Expendable’ Buffalo Bills WR Named NFL’s Top Trade Candidate appeared first on HEAVY.
In New Mexico governor’s race, Deb Haaland’s historic bid tests Democrats' political hold
If Deb Haaland wins New Mexico’s race for governor, she’ll make history as the first Native American woman to lead a state.
Triad Business Bank renews criticism of M&F Bank deal
Greensboro’s Triad Business Bank launched more criticism of the plan by Durham-based M&F Bancorp, to merge into a larger African-American-owned peer, Optus Financial of Columbia, South Carolina. M&F has rebuffed offers since August from Triad, which hopes to derail M&F’s combination with Optus in a transaction valued at about $105 million. M&F plans a Nov. […]
Iowa businesses recognized as top 100 US small businesses
Three Iowa businesses were named to the U.S. Chamber of Commerce’s 2026 CO—100: America’s Top 100 Small Businesses list. The CO—100 recognizes small businesses for their growth, innovation and commitment to their customers, according to a news release. Original Group Holdings, a woodworking equipment manufacturer in Britt, was recognized as a community champion. The company…
This Chicago Mansion Is Hiding A World Of Magic Behind Its Historic Doors
Located near the Magnificent Mile, The Hand & The Eye offers three floors of immersive illusions, fine dining and secret passages.
Electronic Arts Closing BioWare, Laying Off Hundreds
Around 400 people are expected to be laid off across Electronic Arts
Illini Bluffs star commits to Missouri Valley Conference volleyball program
Illini Bluffs junior Emerson Eeten helped her team to a Class 1A regional title match as a sophomore. Now, she's headed to the Missouri Valley Conference.
Tom Izzo Unloads on Trey Kaufman-Renn’s Sixth-Year Ruling
Tom Izzo did not hold back on the court ruling that sent Trey Kaufman-Renn to Kansas. #Spartans
Florida's manufacturing ambitions take flight as aerospace, medtech giants fuel Sunshine State's economic push
Florida is moving beyond tourism as aerospace and medtech giants drive an manufacturing boom aimed at securing a top-10 global economic ranking by 2030.
Franciscan Health receives stuffed animals for pediatric patients across Northwest Indiana
Pediatric patients in Franciscan Health emergency rooms, pediatric inpatient units and outpatient surgery centers in Michigan City, Chesterton, LaPorte, Dyer and Munster will now have stuffed animals to help make their hospital experience a little more comfortable, thanks to a donation by The Eva Martin Project. Representatives from The Eva Martin Project recently donated more … Continued
Defense contractor cuts ribbon as first in Omaha Airport Business Park
A defense contractor and manufacturing company cut the ribbon Wednesday on a second North Omaha location. It's the first in the Omaha Airport Business Park.
Science Lab: Dear Cowboys, run the ball.
Welcome to "The Science Lab", a place where football facts and in-depth analysis always triumph over feelings.
Pacific Engineering opens facility in North Omaha Business Park, lands Navy contract
Pacific Engineering cut the ribbon to open its brand new manufacturing facility along Abbott Drive.
Bills Have Made Their Feelings on Rookie Davison Igbinosun Clear
Jim Leonhard says Bills rookie Davison Igbinosun has earned a bigger role at cornerback, but penalties and technique remain areas to improve.
The New Rules of Global Brand Growth
Last week, BoF, ESW and Shopify gathered senior fashion and retail executives from Thom Browne, Reebok, Alo Yoga, Harvey Nichols, Bang & Olufsen and more in London to discuss how brands can win back consumer spend, protect margins and localise in a climate where global growth requires more consideration than ever.
Dayton defense contractor Mile 2 names new ‘C’-level executives
Mile 2, a growing defense contractor in downtown Dayton, has appointed Matt Phaneuf as COO and Kyle Garza as its first CTO to enhance delivery of mission-focused solutions for the Department of Defense and national security clients, leveraging their combined 30 years of industry experience.
Suspects wanted for string of business burglaries in Fairfax County
Police are searching for suspects accused in a string of Fairfax County business burglaries.
Truffle business to host grand opening in Pittsfield
Truffles by Tarah, a Berkshire County based truffle business will be opening its first storefront in Pittsfield on Oct. 31. A grand opening celebration and ribbon cutting will take place at noon.
Understanding Illicit Political Finance to Counter State Threats
In 2024, Western governments warned that Russia was actively interfering in Moldova’s elections, seeking to prevent the re-election of pro-European Union politicians. This interference targeted Moldova’s political system from multiple angles, including covertly funding political actors and protest movements. There were widespread reports of vote-buying, including cash payments of up to €100 to voters. Reports […]
Reviewing the Most Impactful Penn State Transfer Portal Departures
Penn State experienced a tumultuous 2026 offense. It was a carousel wash of players and coaches shuffling in and out of the Latsch Building, with 40 transfers entering and 47 transfers exiting. At 3-4 overall and 0-4 in Big Ten play, Penn State seems to be on the short end of the transfer portal transactions. …
Inside Amer Sports: Making and moving the product
Follow Amer Sports products from manufacturing in Romania to distribution in Germany, powered by skilled people, precise processes, and technology.
RayNeo Announces Canadian Retail Rollout for Its Next-Generation AR Entertainment and AI Glasses
GT MAX brings a virtual screen of up to 307 inches, while RayNeo iO Smart Glasses puts everyday AI in view, as part of a full Canadian lineup with glasses starting at $429 RayNeo GT MAX RayNeo GT MAX AR glasses pair a 59° field of view with virtual screens of up to 307 inches. Built-in audio is co-tuned by Bang & Olufsen, and Dolby Vision is supported when paired with the separately sold Pocket TV Pro.* MSRP $629 CAD. Screen image simulated. Photo: RayNeo RayNeo iO RayNeo iO AI glasses put live
There’s a Reason That Netflix’s Ad Business Has Underwhelmed
Somewhat lost in the company’s slew of firings and engagement warnings over the past few weeks was the fact that Netflix is scaling back its ad forecast for 2026 from $3 billion to $2.7 billion. That’s despite the fact that: CTV is growing by 14-15% this year This year saw a monster upfront Netflix is the biggest streamer out there this side of YouTube, and was the platform that for years brands were supposedly dying to be a part of In other words, that’s an alarming pull-back from Netflix. A Wall Street analyst I spoke with last week was blunt, calling Netflix’s ad business “disappointing.” To me, a red flag on the ad front is that Netflix has never revealed how many ad-supported subscribers it has. Because if I know anything about how big companies work, if they have a positive number that makes them look really good - they tend to share it. (How many subs does go90 have right now? We’re not saying just yet. How are ads going on ChatGPT? Oh, a billion run rate - I see). Yes, to date Netflix has shared some fuzzy ad numbers, such as the idea that the company’s ad tier ‘reaches’ 250 million users globally.’ Here’s why that figure gives me pause: a)they lead with global, and b) they don’t explain how they are calculated. (Are they based on average people in each room? Surveys of some kind?). Regardless, some insiders say that Netflix’s ad tier is scaling nicely - others not so much. Either way, one of Netflix’s biggest challenge on the ad front appears to have been its starting point. Remember, when Netflix launched ads in 2022, it had 73 million subs in the US and Canada. That’s 73 million people who were used to Netflix with zero ads. And when the ad product rolled out, the company clearly was going after new users - a limited pool of potential subscribers by default. That focus seems to have changed over time, as Netflix has tried to convert longtime subscribers to the ad tier. Historically Netflix subscribers are very sticky. But is the company’s low churn a problem? Not necessarily, according to Antenna data. Rather, Netflix’s consumer loyalty is a bit of a double-edged sword. “Netflix is the one streamer which actually has seen substantial “trade downs” but has much lower ‘win backs,’ said Antenna founder Jonathan Carson (win-backs being people who were on the ad-free plan, cancelled, then rejoined on the ad plan). “Netflix has lower churn and so has less opportunity to win back old subs with a lower cost plan option.” This all might explain why Netflix has been so slow to roll out all of these table stakes targeting options until just this week. It likely didn’t have enough users to carve up into various targets. etc. However, what really hit Netflix’s ad business was Amazon’s move a few years ago to turn on advertising for Prime Video by default. Suddenly the market was awash in premium inventory, and Netflix was playing catch-up on multiple fronts. Thus, the streaming giant appears to still be figuring out if if wants lead in ‘programmatic TV,’ or premium ‘upfront’ TV sales. “The CTV market now sorts into three businesses, and Netflix is not the leader of any of them,” wrote analyst Jack Myers. Ouch. So how does Netflix ratchet up its ads business? Get the next NFL package You’re gonna have to wait until 2030 unless one of the bigger media companies like Skydance opts out, but the easiest (not cheapest) way for Netflix to become a huge TV ads contender is to get one of the regular NFL packages, ideally Sunday afternoons. That way it can sell ads to its whole U.S. subs base overnight. Go FAST This one is risky, because to program a compelling FAST channel, you’d likely have to take some older Netflix exclusive shows and make them available for free to non-subscribers. But FASTs, for better or worse, are ad-inventory machines. Go full UGC I’m not sure I see this happening. There is something already off about Netflix carrying podcasts and shows for creators. The experience sticks out in what is such a produced, and generally non-communal environment. But Netflix could open up its platform by allowing creators to upload videos without having to be approved by the service. But that opens a whole other can of worms (policing brand safety, copyright infringement, overall quality). Make a huge RMN Deal I was going to suggest something crazy, such as ‘instead of buying Warner Brothers, Netflix should buy Target. But the company doesn’t want to be in the brick and mortar business. Yet for Netflix’s ad business to compete in an Amazon world, it needs to be able to connect ad exposures to shopping. What if, instead of letting Amazon target Netflix viewers with its DSP, Netflix inked a deal with Target, or even took control of Roundel, and created its version of the Amazon full-funnel for brands? Price us out. I hope they don’t do this, but Netflix’s price increases - while significant - haven’t been enough to push long-term customers out of the ad-free tier. But if they made those prices so prohibitive, it could push large swaths of consumers to trade down. Then again, that could also dent engagement - as binging becomes much less appealing once you bring ads into the equation. Or, they could just launch a bunch of hit shows and maybe everyone will quickly forget all this angst. More from Amazon unBoxed A few weeks ago, I recorded two podcasts live at Amazon’s unBoxed event in San Francisco. I was able to go really deep with several brand partners about how Amazon’s various data and ad products work - particularly the under appreciated Amazon Marketing Cloud. First, I talked with Laura Abadias Velilla, of the Amazon specialty agency Amerge, along with Amazon’s own Charlotte Maines, Vice President, Devices Content & Advertising, about how the two partners helped a very specific printer company Epson launch into a brand new category - high end projectors. It’s a great example of how brands connect audience data across platforms to make budget deployment decisions. Next, I chatted with Monks VP Head of Digital Investment for North America Tom Burchill about how the agency actually brought in data from Linkedin to help target B2B customers across various Amazon properties for the brand Quicken. Check it out: Check these out, or just listen:
Science-oriented company promotes field for women
A company that makes laboratory supplies marked the anniversary of its Mebane plant by holding an event honoring the women driving progress in STEM and advanced manufacturing careers across the
Scrap exports deepen Europe's aluminum shortage
Aluminium is becoming scarcer and more expensive in Europe as growing volumes of scrap are exported abroad. Manufacturers are urging the EU to impose export restrictions.
AI as the next political divide
We have a guest post today from our friends at Focaldata, with whom we have done polling before. They have been doing a lot of work on attitudes towards AI and how this is affecting politics on both sides of the Atlantic. In this post, they explore exclusive new polling – with a whole set of fascinating charts on how voters’ views are developing and why. In particular, the authors explore why the debate is currently so much more polarised by party in the US than in the UK, to the benefit of the Democrats. Subscribe Focaldata HQ is located in Shoreditch, east London. To access the office from the Shoreditch High Street Overground station, you have to walk under the bridge at Braithwaite Street. We mention this not as a navigational aid, but because the posters above caught our eye over the summer. Since June, the area has been the centre of a fiercely contested debate around the construction of a data centre on the Truman Brewery estate on Brick Lane, less than 200 metres from our office. It was one of the first ‘US-style’ protest movements around AI data centres the country has seen, and may not be the last. These protests served as the catalyst for our forthcoming report, examining whether AI could become the next political divide on both sides of the Atlantic. We wanted to understand what was driving the emerging politics of AI and whether the dynamics at play in the US offer clues as to how the British debate will evolve. Over the last month, we polled 3,851 people across the UK and US about their views on AI. Our research found striking similarities between the two countries: for instance, both electorates are evenly split on their views towards AI development, with just over a third in favour (37% in each country), a similar number opposed, and the remainder somewhere in the middle or unsure. Statistically speaking, there is no difference in overall sentiment towards AI between the UK and US. Under the hood, demographic patterns also look largely the same in the two countries, with millennials, degree holders, full-time workers and those who describe themselves as financially comfortable more pro-AI than the rest of the country. Despite this convergence in overall attitudes, there is a striking divergence in how much of a politicised issue AI has become. In the US, attitudes are increasingly split by political affiliation and the issue has become the latest front in the seemingly interminable culture war, playing a role in the upcoming midterms. This stark political polarisation of AI has not happened in the UK – at least not yet. In what follows, we test several hypotheses for why the two countries are so far apart on a political basis. Understanding which hypothesis is correct will give us an indication of where the British dynamics go next.
Brookshire Brothers opening new location with premier outdoor entertainment venue Nov. 11
Brookshire Brothers will open the doors to its newest Lufkin location at 6 a.m. Wednesday, Nov. 11, bringing an enhanced grocery shopping experience, expanded services and a premier outdoor entertainment
Kansas manufacturing business responds to candidates’ conflicting accounts of tariff effects
KANSAS CITY, Mo. — The two major party candidates for U.S. Senate diverged in a debate Wednesday night on whether tariffs were helping or hurting a Salina manufacturing business they both visited. A spokesperson for the business, however, denied U.S. Sen. Roger Marshall’s claim that tariffs were contributing to its growth. Tim Henry, chief financial […]
James Webb telescope discovers surprising trove of metals around the Milky Way's supermassive black hole
New observations from the James Webb Space Telescope reveal a concentration of heavy metals near the Milky Way's central black hole. The discovery deepens a mystery about why our black hole behaves the way it does.
Computer science student takes engineering skills to Neuralink
A challenging classroom project helped Mateo McKee land an internship developing software that supports the manufacturing and testing of Neuralink’s brain implants.
Guns, Taxes and Traffic Cameras: The Midterm Ballot Measures to Watch
Not every closely watched contest in this year’s midterms is about candidates. Some will ask voters directly about the issues. In 39 states, voters will weigh ballot measures, including questions placed by legislators and others lodged by members of the public who gathered a sufficient number of ...
Prisma Health offers walk-in mammograms in October for Breast Cancer Awareness Month
Prisma Health is offering walk-in mammograms to make breast cancer detection easier.
Alyson Hannigan uses real ‘Buffy’ set pieces as Halloween decorations, including iconic Spike prop
‘Buffy’ star Alyson Hannigan decorates her house for Halloween with set pieces from the show, including iconic Spike prop.
United Automobile, Aerospace & Agricultural Implement Workers of America
The labor union representing workers in auto, aircraft and agricultural implement manufacturing and other industries in the U.S., Canada and Puerto Rico.
“A Huge Relief”: Stand Up for Science Celebrates Stopping Controversial Hep-B Vaccine Study in Guinea-Bissau
Following the news that the controversial Hepatitis B vaccine safety study in Guinea-Bissau newborns has been canceled permanently, Stand Up for Science is
National High Magnetic Field Laboratory will develop cutting-edge nuclear magnetic resonance facility with $18M in funding
The project supports National Science Foundation priorities in biotechnology, energy, advanced manufacturing and health The National High Magnetic Field
Winnebago health system breaks ground on 90,000-sq-ft expansion
WCHS states that the new additions will include 90,000 square feet of new additions and renovations.
Zach Charbonnet Injury Update: Seahawks RB’s Week 7 Status Revealed
Zach Charbonnet was supposed to be the leader of the Seattle Seahawks backfield in 2026, but the veteran running back has yet to suit up thanks to an ACL injury he suffered during the team's Super Bowl run last season. Originally selected in the second round of the 2023 NFL Draft, the UCLA product spent …
Nearly 100 cases of norovirus reported at Kansas elementary school, officials say
A Kansas elementary school suffered an outbreak of norovirus that impacted nearly 100 people, health officials said.
What happened to Ben Kindel? NHL player suffers 'medical episode' on plane
Pittsburgh Penguins forward Ben Kindel was taken to a Utah hospital Tuesday after suffering a "medical episode" on the team plane.
Tennessee Titans re-sign Erick Hallett to the practice squad
The Tennessee Titans released veteran Jordan Elliott and shuffled their practice squad roster ahead of the Cleveland Browns game.
Alexis Levine presents theory for why only women have been voted out of ‘Survivor 51’
Alexis Levine presents her theory for why only women have been voted out of ‘Survivor 51’ and reveals a crazy, bloody scene that did not make it to air.
Lamar Jackson Injury Update: Ravens QB’s Week 7 Status Revealed
Lamar Jackson suffered an ankle injury in Week 4, and the two-time NFL MVP left the game in a walking boot. While this was originally reported to be a minor injury, the two-time MVP missed Weeks 5 and 6 and is in danger of missing Week 7 as well. Originally entering the league as a …
How GSN Doctoral Residents are Approaching Care for Military Women’s Health
A Navy nurse and GSN doctoral resident redesigned an Okinawa maternity unit, cutting off-guideline staffing from 18% to below 12%.
A political forum was going normally. Then police were called
A New York political candidate was detained and released without charges after a confrontation at a forum involving her opponent’s mother.
‘It Was a Source of Great Joy’
A short profile of Tufts University faculty member Kristen Wendell
Trump shuffles key federal panel ahead of vote on his arch
Four Trump political appointees were added to the National Capital Planning Commission, which could approve the president’s project on Nov. 5.
“A Huge Relief”: Stand Up for Science Celebrates Stopping Controversial Hep-B Vaccine Study in Guinea-Bissau
Following the news that the controversial Hepatitis B vaccine safety study in Guinea-Bissau newborns has been canceled permanently, Stand Up for Science is
Former Lakers Guard Gets Another Shot With Western Conference Squad
Former Los Angeles Lakers guard Kobe Bufkin, who spent 2025-26 with the team, joined the Utah Jazz just before the start of the season. The post Former Lakers Guard Gets Another Shot With Western Conference Squad appeared first on LA Sports Report.
United Automobile, Aerospace & Agricultural Implement Workers of America
The labor union representing workers in auto, aircraft and agricultural implement manufacturing and other industries in the U.S., Canada and Puerto Rico.
Grading the Buffalo Bills Special Teams At The Bye Week
Tyler Bass’s perfection and a game-changing blocked kick anchor a dominant unit. From field position battles to return-game sparks, these specialists have earned their elite midseason marks.
Catholic association launches online courses to equip faithful for mental health ministry
The International Association of Catholic Mental Health Ministers launched two online courses to help the faithful recognize mental health struggles and learn how to support those who are suffering.
Chandler family acquires specialty truck manufacturer
Springdale business owners Chris and Morgan Chandler recently acquired Stephenson Specialty Trucks LLC, a Parsons, Kan.-based manufacturer of vacuum, grapple, roll-off and hook lift trucks. Financial terms of the deal...
LIVE: Heavy police presence at Academy Sports + Outdoors in Humble as crime scene investigated
Humble police are investigating a crime scene at an Academy Sports and Outdoors on Wednesday, according to the Police Department.
How governments around the world are shaping what AI can say about politics
I’m a researcher at a nonpartisan think tank at Vanderbilt University, where I study free speech policy.
Junior nets game winning goal for Utica Academy of Science boys soccer in Class B 1st round
The Atoms get their first sectional victory since the 2023 season.
Woodruff makes Brewers' World Series roster as he returns from shoulder injury
Woodruff took the place of Chad Patrick on Milwaukee’s 13-man pitching staff as the Brewers and Tampa Bay Rays submitted their World Series rosters Friday before playing Game 1 in Milwaukee.
New Richland Lab Could Transform How Scientists Study Microbes and Boost Regional Jobs
The BriefGroundbreaking held Tuesday: PNNL officially began construction on the M2PC lab, a 30,800-square-foot facility funded by the U.S. Department of Energy's Office of Science that will study soil microbes to improve crop productivity and develop new biotechnology applications. The facility will be open to researchers from around the nation and the world.Research timelines could shrink dramatically: The facility's automation and AI capabilities could reduce experiments that currently take six months to just 72 hours, allowing scientists to explore more possibilities faster than ever before.New jobs coming to the Tri-Cities: The project is expected to create positions for automation engineers, AI experts, roboticists, technicians, and skilled craftspeople, with the facility opening in 2029.RICHLAND, Wash. — Pacific Northwest National Laboratory broke ground Tuesday on a first-of-its-kind facility that could accelerate scientific discoveries about the microscopic organisms living in soil—organisms that may hold the key to growing more food and developing new energy technologies.The Microbial Molecular Phenotyping Capability, or M2PC, represents a significant investment in automation and artificial intelligence to speed up research that traditionally takes years to complete. The 30,800-square-foot facility will house more than 100 connected automated instruments designed to study microbes at a pace and scale never before possible.Reshaping Agriculture's FutureThe M2PC facility will not put a new tool directly into a farmer's hands tomorrow morning, but it is actively reshaping the commercial pipeline to solve agriculture's biggest headache with biologicals: inconsistent field performance. For years, PNNL researchers have explored how microbes work and how they might help produce useful materials, advance energy technologies, and address challenges involving critical materials and minerals. But those experiments have been limited by what researchers could accomplish by hand."They can be used to provide nutrients to a plant so that the plant would grow more. So, like increasing your crop productivity, for example," said Douglas Mans, PNNL's Associate Laboratory Director for Integrated Discovery Sciences.PNNL's own research shows soil microbes can help plants access nutrients and withstand drought—benefits that could prove crucial as farmers face growing environmental pressures. The M2PC facility will allow scientists to identify and optimize useful microbes faster than ever before, accelerating the development of biological solutions that actually work consistently in the field.What Makes M2PC UniqueThe Microbial Molecular Phenotyping Capability differs from traditional research labs because it operates as a first-of-its-kind, AI-enabled autonomous laboratory designed to shrink experimental timelines from years down to months or weeks. The M2PC lab will connect more than 100 automated instruments to grow microbes, prepare samples, measure their behavior, and link observations to the molecular processes behind them. Artificial intelligence will help analyze results and guide the next experiments, allowing scientists to explore more questions faster.Deb Gracio, PNNL Director, emphasized the transformative potential during Tuesday's groundbreaking ceremony: "Research that has taken years will become possible in months and hopefully in weeks."That acceleration is already being demonstrated. PNNL's smaller automated lab, called the Anaerobic Microbial Phenotyping Platform or AMP2, completed three experimental cycles in just 72 hours—a process that normally would have taken about six months."That normally would have taken us about six months … and we were able to do that in 72 hours," Mans said.The AMP2 laboratory is not being closed or replaced. Instead, the current 1,800-square-foot laboratory serves as an active prototype and precursor for the much larger M2PC facility. AMP2 will continue operating as a separate lab designed to run anaerobic experiments—those conducted in the absence of oxygen—while M2PC will focus on aerobic research.Broader Applications Beyond AgricultureWhile improving crop productivity is one important application, the M2PC facility is designed to support research into multiple areas critical to national priorities. The lab will advance research into biofuels, manufacturing materials, and energy technologies. It will also help researchers understand how microbes respond to environmental changes and how to design biological systems for biotechnology applications.As a flagship component of the Department of Energy's Genesis Mission, M2PC represents a significant investment in using artificial intelligence and automation to accelerate U.S. scientific discovery. Dorothy Koch, Associate Director of the DOE Office of Science Biological and Environmental Research program, highlighted the facility's importance during the groundbreaking."M2PC will accelerate biological discovery and design," Koch said, noting that the facility is expected to conduct a minimum of 500 strain experiments per week, 100 microbiome experiments per week, and take a million measurements per month.Economic Opportunity for the RegionBeyond the scientific breakthroughs, the M2PC project represents significant economic opportunity for the Tri-Cities region. The facility will require hiring automation engineers, AI experts, technicians skilled in operating robotics, and specialized craftspeople to build and maintain the sophisticated equipment."We're anticipating that type of hiring," Mans said when asked about job creation.PNNL has already begun recruiting talent nationally and internationally for positions related to the smaller AMP2 lab, bringing automation engineers from cities like Boston and San Francisco to work in the region. The M2PC facility is expected to accelerate that trend."This capability won't really exist anywhere else in the world," Mans said, suggesting the facility could become a draw for scientific talent seeking to work on cutting-edge biotechnology research.Timeline and Next StepsThe M2PC facility is expected to open in 2029. Between now and then, construction crews will level and prepare the ground, while the building takes shape. Simultaneously, Ginkgo Bio Works, the automation contractor, will build the facility's automation components off-site so they can be installed as the building is completed.In the interim, PNNL researchers and the broader scientific community will begin planning the first experiments to be conducted in the facility, ensuring research is lined up and ready to begin as soon as the doors open.The groundbreaking ceremony included representatives from the Department of Energy, PNNL leadership, and elected officials at the federal, state, and local levels, underscoring the project's significance to the region and the nation's biotechnology future. News The U.S. Department of Energy Secretary tours Pacific Northwest National Laboratory Dan Hanson, Apple Valley News Now News Beyond DNA: Scientists Explore New Frontiers in Biology Research Dan Hanson, Apple Valley News Now News TRIDEC optimistic that Hanford, PNNL will see funding in national budget Robert Desaulniers News Big picture science: monitoring the Yakima River Basin News PNNL research could shape the future of fighting fentanyl COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
Bills Defender Sounds Off on Early Defensive Troubles
Christian Benford addresses Buffalo’s bottom-tier statistical ranking, citing scheme adjustments and roster turnover as the secondary works to mirror Josh Allen’s elite offensive production during a 5-1 start.
Critical GitLab Flaw (CVSS 10.0) Could Allow Unauthenticated RCE Across 12 Years of Releases
GitLab fixes CVE-2026-110264, a critical flaw that could allow unauthenticated code execution on self-managed versions dating back to 7.0.
USA TODAY Entertainment reporter Anna Kaufman goes behing the scenes at "Dancing with the Stars" to train with professional dancer Brandon Armstrong.
USA TODAY Entertainment reporter Anna Kaufman goes behing the scenes at "Dancing with the Stars" to train with professional dancer Brandon Armstrong.
Paul George Makes Celtics History With Record Breaking Debut
Paul George wasted little time making history with the Boston Celtics, delivering a spectacular performance in his first game with the franchise. Despite Boston suffering a 121-113 loss to the Detroit Pistons on Tuesday night, George gave Celtics fans plenty of reasons to be excited about what he could bring to the team this season.…
Australian treasurer says opponents want higher inflation for political gain
In a Canberra Playbook Podcast interview Jim Chalmers accused Liberals of wanting Australians to suffer, as their path back to power.
5 Startups to Pitch at UToledo Business Incubator’s Tech419 Oct. 29
Three of this year’s five finalists have UToledo ties, with ventures spanning space research, orthopaedic surgery, manufacturing and facility maintenance.
UFL owner explores St. Louis stadium alternatives due to Dome schedule conflicts
League owner says UFL is not leaving the "BattleDome" but is exploring other options for better scheduling flexibility
When computer science meets the alpaca immune system
After earning bachelor's and Ph.D. degrees in bioengineering with a focus on molecular biology, Will White, a postdoctoral scholar in the Department of Computer Science at Tufts, was pretty certain his ...
Case of mysterious medieval skeleton buried in Roman-era sarcophagus at Westminster Abbey finally solved
A sarcophagus in Westminster Abbey with Roman and Anglo-Saxon decorations baffled archaeologists, but now a 150-year-old mystery has finally been solved.
Political communications expert discusses Vivek Ramaswamy's controversial ad
NPR's Steve Inskeep speaks with political communications expert Jacob Neiheisel from the University of Buffalo about Vivek Ramaswamy's controversial ad.
Brewers Place Brandon Woodruff On World Series Roster
The Milwaukee Brewers have placed Brandon Woodruff on the World Series roster
Forge Nano to Trade on NASDAQ as NANO After Completing Business Combination with Archimedes Tech SPAC Partners II Co.
Forge Nano common stock and warrants expected to begin trading on NASDAQ on October 22, 2026 under the symbols “NANO” and “NANOW,” respectivelyPublic listing positions Forge Nano to accelerate growth across semiconductor manufacturing equipment and advanced battery technologies DENVER, Oct. 21, 2026 (GLOBE NEWSWIRE) -- Forge Nano, Inc., a leading U.S.-based semiconductor equipment and advanced materials company pioneering Atomic Layer Deposition (“ALD”) technology for artificial intelligence (“A
How well have past GOTY winners sold?
We’re less than two months away from 2026’s The Game Awards, and what a year it’s been for fantastic games, including Resident Evil Requiem, Forza Horizon 6, Slay the Spire II, the Blood of Dawnwalker, and Control Resonant – just to name a few. So as we approach the end of the year, we thought we’d look back on our estimates for the GOTY winners of the past four years. In terms of revenue, Elden Ring (2022 winner), Baldur’s Gate 3 (2023), Astro Bot (2024), and Expedition 33 (2025) have generated a combined $3.8B via 73M copies sold: Let’s have a look, then. Elden Ring has generated $2B in revenue Elden Ring is a phenomenon in every sense. It’s sold a whopping 36.4M copies across Steam (50%), PS5 (35%), and Xbox (15% across console and PC). Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Elden Ring also just passed an astronomical milestone: $2B in revenue. While PlayStation and Xbox account for half of Elden Ring’s copies sold across these three platforms, they account for 57.5% of revenue. This – as ever – is due to regional pricing and the higher relative share of PC gamers in lower-priced markets. For example, around 17.4% of Elden Ring’s Steam copies sold were in China, where the game costs about 26% less than the price in the States. There’s an … interesting narrative going around these days that console gamers are only interested in ball-and-gun games and have the patience for little else. Well, Elden Ring’s impressive sales prove that is simply not true, and across all platforms. What’s more, over 9.8M people have played Elden Ring for over 100 hours, with nearly 3.5M people getting all of the achievements and trophies. For reference, 10.9% of Elden Ring’s PlayStation players have the platinum trophy, while 10.5% of players on Steam and 3.9% of Xbox players unlocked all the achievements. Git gud, Xbox players! Of the 1.5M people who played Elden Ring on PlayStation last month, 4% also played Dark Souls 3 last month, 4% played Bloodborne, and 3% played Sekiro. There’s those Soulsborne diehards for you. By many accounts, including my own, Elden Ring is one of the best games of all time. It’s an evergreen seller that will continue to be a cash cow for Bandai and FromSoftware for years to come. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Elden Ring has sold another 2M copies across Steam, PlayStation, and Xbox this year, generating almost $110M. This means it’s outperforming many of this year’s high-profile releases. Even Elden Ring’s standalone run-based PvE spinoff, 2025’s Nightreign, has sold 7.8M copies and generated $282M in revenue. Baldur’s Gate 3 is another billion-dollar-plus banger Another cross-platform phenomenon is Baldur’s Gate 3, which has sold 23.2M copies and generated over $1.2B in revenue. About 18.7M of these copies (80.6%) are via Steam, 2.9M via PS5 (12.7%), and 1.6M (6.8%) via Xbox. Around 1.3M folks on Steam bought BG3 before it hit 1.0. The PlayStation version launched about a month after the PC 1.0 release, while the Xbox version came four months later due to technical issues around developing local co-op on the Series S. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Across platforms, Baldur’s Gate 3’s monthly active users have never dropped below 2M, including 2.2M MAUs last month (68.5% on Steam, 21.9% on PS5, and 9.6% on Xbox). And it still regularly brings in 280K to 400K players every day: About 1% of BG3’s Steam player base has played for over 500 hours! That’s a little under 200K people. Astro Bot is also an evergreen seller, albeit a more niche, family one Astro Bot, 2024’s winner, has now sold 4.7M copies and generated $291M in revenue. The budget, including marketing, is almost certainly under $100M, given the small Japan-based core team and three-year dev timeline. You can really see why the tides are changing toward less expensive hubs. Astro Bot is the only first-party winner on this list, but follows other first-party winners of The Last of Us Part II (2020’s winner), God of War (2018), and Breath of the Wild (2017). Around 46.6% of Astro Bot’s copies sold have been physical, which is far higher than the typical game. This makes sense for a couple of reasons: There’s a large family audience for this one, and physical boxes are an item to wrap when giving Astro as a gift. Astro has collector value for the PlayStation core (this is nostalgia-fueled platformer celebrating PlayStation’s history) Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Astro is another one of those games that continues selling over time, regularly selling more than 100K a month. It’s sold around 1M more copies this year ($60M in revenue) and is a popular title with families. We can see this using the Alinea platform’s MAU crossover tool: Astro Bot’s top #2, #3, and #4 games by crossover in any given month this year are Minecraft, Fortnite, and Roblox – without fail. The #1 title every month, though, is Astro’s Playroom, a pack-in with all PS5 consoles. For every month this year, between 20% and 30% of Astro Bot players also played Astro’s Playroom that month. So the free pack-in is a noice funnel for converting players to a full paid product. Expedition 33 sells 8.7M despite Game Pass cannibalisation Finally, we have last year’s winner – Expedition 33. The turn-based-RPG banger has generated $366M via 8.7M copies sold, with 58.8% on Steam, 35.7% on PS5, and 5.5% on Xbox. Xbox’s share of copies sold is this low due to Expedition 33 launching on Game Pass, where 4.3M people across console and PC accessed the game. A little under 700K Xbox players used their subscription to play Expedition 33 this year. That said, the game’s 1.5-year Game Pass deal ended last week on October 16, and we’re already beginning to see a positive trend on Expedition 33’s copies sold via Xbox (but the jury’s still out!). There’s understandably a lot of French pride behind this one, as France is the game’s #3 market on both Steam and PlayStation. Vive la France! One thing that stood out to me is that the GOTY winners aren’t $300M Hollywood productions made in the US. They’re mostly mid-budget studios outside the traditional AAA cost centres. Lots to think about there. Also, good games sell well; who’d have thunk it!? And there’s a whole load of them this year, with GTA 6 still to come, too. GTA just made the cutoff point for the VGAs this year. What a coincidence! Loading... Cool links and other stuff Our physical games newsletter from Tuesday was picked up by GameSpot, Eurogamer, TweakTown, and a bunch of others. We’re offering a free trial of our platform for games companies. Send us a message here, or reply right here on Substack/email, and we’ll set you up. Next week, we’ve got some exciting news regarding the future of our newsletter, so stay tuned! The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. Want to see why these companies (and many others) are subscribed to Alinea? Get a free platform trial! [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]
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