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Zelenskyy says Putin’s statements on readiness for peace talks could be a ‘political trick’
Ukrainian president argues Russian intentions would become clear through its actions, readiness to reach agreements | Anadolu
Ivica Zubac (left ankle sprain) will not return to …
Ivica Zubac (left ankle sprain) will not return to …
Quinshon Judkins flirts with century mark in Week 7 return
Cleveland Browns running back Quinshon Judkins (ankle) rushed 17 times for 96 yards and two touchdowns in Week 7
“Odegaard was outstanding” but Merson was less complimentary about Gyökeres
Paul Merson has delivered contrasting verdicts on two Arsenal players following Saturday’s comfortable 2-0 victory over Everton, singling out Martin Ødegaard for praise while questioning Viktor Gy�...
Open Thread: Colorado Avalanche @ Nashville Predators (6:00 P.M. MDT)
Tonight is another Colorado Avalanche game day as they pay a visit to Nashville to face the Predators!
Sports equinox 2026: Date, schedule, meaning and history behind the rare event
The 33rd sports equinox will occur in 2026.
Kids celebrate with big Halloween fun at University Health's Fall Fest!
Hundreds of children who were born prematurely or with special needs reunited Thursday night for University Health’s annual Halloween Fall Fest, turning a night that was only open to families into a celebration of
Race Results: 2026 NASCAR Cup Series YellaWood 500 at Talladega
Kyle Larson took a thrilling win in a wild last-lap rally that led to a photo-finish with William Byron, his Hendrick Motorsports teammate. Larson, who was eighth heading down the backstretch of the final lap, had everything go his way ahead of him, as he sliced and diced his way back to the front. Ricky […] The post Race Results: 2026 NASCAR Cup Series YellaWood 500 at Talladega appeared first on TobyChristie.com.
Vikings’ Aaron Jones Exits Colts Contest With Scary-Looking Injury
The Minnesota Vikings saw running back Aaron Jones Sr. go down with a leg injury late in their Week 7 game against the Indianapolis Colts. The post Vikings’ Aaron Jones Exits Colts Contest With Scary-Looking Injury appeared first on HEAVY.
Eye on Northwest Politics: Oct 25, 2026 (Tina Kotek)
Reporting Portland and Vancouver area breaking news and weather stories to make Oregon and Southwest Washington a better place to live
Pirates Should Re-Sign This Upcoming Free Agent
Gregory Soto could still be a solid piece in the Pittsburgh Pirates bullpen in 2027.
Democrat Coumba Kebe wants to keep the politics out of the treasurer’s office
Political newcomer Coumba Kebe is the Democratic nominee for Indiana state treasurer. Kebe wants to keep the politics out of the office and build back trust with people.
Orlando is leaning towards starting Jase Richardson in …
Orlando is leaning towards starting Jase Richardson in …
Nico Collins disappoints in Week 7 vs. Giants
Houston Texans wide receiver Nico Collins posted two receptions for six yards on five targets in Week 7
Bengals Shut out in Disastrous First Half vs Ravens
The Cincinnati Bengals are off to a first half they’d like to forget. Cincy trails the Baltimore Ravens 13-0 in Baltimore.The story has been the Cincinnati Bengals’ defense which has been struggling against this Ravens offense.The Ravens got off to a hot start as Zay Flowers took a 48-yard pass to the house from backup […] The post Bengals Shut out in Disastrous First Half vs Ravens appeared first on HEAVY.
Aleksandar Vucic concedes defeat in Serbia's parliamentary election, marking political shift
Aleksandar Vucic, who denounced the oppositional student movement as a foreign-led attempt to unseat him, led with virtually absolute power for 14 years.
Cam Skattebo confirms injury after Giants beat Texans in overtime
Cam Skattebo confirmed he did suffer an injury on his 42-yard overtime run.
Novant Health hosting Hilton Head hiring event Oct. 28
Novant Health will host a healthcare hiring event Oct. 28 on Hilton Head Island for nursing, laboratory, pharmacy and other positions.
Aleksandar Vucic: Serbia's veteran ruler felled by student-led movement
The dominant force in Serbian politics for over 14 years, Aleksandar Vucic, who conceded defeat in a snap parliamentary poll on Sunday, rose from the wreckage of strongman Slobodan Milosevic's cabinet...
C.J. Stroud tosses two TDs in Week 7
Houston Texans quarterback C.J. Stroud completed 17 of 28 passes for 153 yards, two touchdowns and no interceptions in Week 7
Clemson’s Loss to Virginia Tech Puts the Program in Flux
Clemson’s loss to Virginia Tech puts the program in flux heading into November. The Tigers now find themselves on the outside looking in on the ACC Championship race after being defeated 20-16 by the Hokies. Dabo Swinney’s team played well in many spots, especially in the third quarter. The complementary football Clemson displayed to start the …
‘Newlyweds’ Stars Debate the Meaning of ‘Dating’
And what it means for Jeanie and James in the series.
Chuba Hubbard has decent outing in Week 7
Panthers RB Chuba Hubbard finishes with 33 rushing yards and 27 receiving yards
🎥 Kylian Mbappé's lucky goal against FC Barcelona
Kylian Mbappé opened the scoring against FC Barcelona this Saturday, October 25.A truly unexpected goal.With both teams looking sluggish from the start, it took until the 42nd minute for the deadlock...
T.J. Hockenson finds end zone in Week 7 vs. Colts
Minnesota Vikings tight end T.J. Hockenson posted four receptions for 35 yards and a touchdown on five targets in Week 7
Bryce Young throws one TD, two INTs in Week 7
Panthers QB Bryce Young finishes with season-low 163 yards and doubles INT total
Remembering Freddie Freeman’s Iconic Walk-Off Grand Slam
Los Angeles Dodgers first baseman Freddie Freeman hit one of the most important home runs in Dodgers history two years ago, today.
New York Giants' Cam Skattebo Just Saved His Job
New York Giants running back Cam Skattebo saved his job against the Houston Texans.
U.S. measles cases more than double what they were last year as outbreak spreads
Pennsylvania is the worst hit state, with at least 1,338 cases of measles confirmed in 44 counties so far this year, according to the Pennsylvania Department of Health.
Liverpool working towards deal for star; could reach €90m
Liverpool are reportedly in the mix for a very in-demand France star. They’re working towards a deal and it’s one that could cost €90m.Liverpool are weighing up their transfer targets for the up...
Photo: Jude Bellingham’s head-turning new boots for Barcelona showdown
Real Madrid star Jude Bellingham has on Sunday evening provided a look at the head-turning footwear that he is set to make use of in El Clásico.The latest edition of Spanish football’s most bitter ...
Primark's Business Doesn't Make Sense
In a world where fast fashion giants like Shein, Zara, and H&M drop thousands of new styles every day — and rake in billions through e-commerce — Primark is doing the unthinkable: thriving with zero online shopping. So what gives?*Want to Know the 5 Trends Changing Modern Retail? Find Out Here:* 🔗 https://clickhubspot.com/d13ac2In this video, we take you inside Primark’s weirdly brilliant business model — a model that’s stuck in the past on purpose. From warehouse optimization and floor-ready freight shipments to why the pandemic didn’t push them online, we unpack how this low-cost retail giant has managed to defy digital norms… and make it work.This isn’t just about one brand. It’s a story about modern retail expectations — and what it actually takes to meet (or reject) them.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot
Zen Browser is the Arc replacement I was looking for
Zen rips off all the best bits of Arc, but skips the AI and bloat.
New heist movie starring Pete Davidson to finally hit theaters in November
Billed as ”Point Break" meets “Fast and Furious,” Davidson will share the silver screen with Nicholas Hoult and Zoë Kravitz.
NZ’s hidden chronic health burden is even bigger than we thought
New research reveals a major gap in how chronic illness is measured, with implications for planning and funding healthcare in New Zealand.
‘Masterplan’: Too lightweight to make an impact
Pretty faces can’t overcome ho-hum plotting
What To Make Of The Washington Nationals Catching Unit
Analyzing the 5 Nats catchers most likely to make a big league impact in 2027
Top Japanese Prospect Has His Eyes on the Dodgers
The Los Angeles Dodgers are the industry favorite to sign the best prospect in Japan, 18-year old pitcher Shoki Oda.
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race
Blanche told CNN's “State of the Union” that President Donald Trump, who said Friday that he was "the one that said do it,” is not trying to overturn state election results “in any way, shape or form” on the cusp of the Nov. 3 election.
Uganda tightens Ebola border controls and requires returnees from Congo to pay for quarantine
Uganda is reinforcing existing border controls requiring citizens returning from Congo to undergo 21 days of quarantine at their own expense, the Health Ministry said Sunday, as investigators examine how a woman who traveled from Uganda to Nigeria cont...
Knicks Have Clear Advantage Over Magic With Lopsided Injury Report
The New York Knicks look for their first win of the season.
Steelers stock report after Week 7 win over Saints
Stock up, stock down, after the Steelers Week 7 win in Paris over the New Orleans Saints.
Schefter: Seahawks among teams ‘expected to consider’ Jonathan Taylor trade
The Seahawks are “pondering” adding Taylor in hopes of saving their run game.
Union County Best of the Best Business of the Year Magnolia Renovations Joshua Andrews, owner
What was your reaction when you learned your business had been named Business of the Year?
Nico Williams publicly disavows his agent over Barcelona transfer claims
Barcelona’s long and drawn-out pursuit of Nico Williams has become one of the more familiar sagas of recent transfer windows.The Athletic Club winger ultimately opted to stay at San Mames, snubbing ...
What Will It Take for Rockies to Make World Series?
It's been since 2007 for the Colorado Rockies to be a part of the World Series. Is there any hope for a return to the Fall Classic?
How Argentina’s Folk Sounds Are Shaping a Generation’s Politics and National Pride
Milo J, Cazzu, and more stars are embracing music and traditions of the Argentine countryside, staving off pop homogenization and sharing their history with the world
Jaylen Warren surpasses 100-yard mark in Week 7
Steelers RB Jaylen Warren rushes for at least 100 yards for third time this season
Broncos Place Linebacker, Running Back On Injured Reserve
The Denver Broncos have a fluid injury situation, with Tyler Badie and Jonah Elliss being placed on injured reserve.
Warren, Steelers stiff-arm Saints for 16-10 Paris win
Jaylen Warren had another big day and the Pittsburgh Steelers overcame some red-zone inefficiency to beat the New Orleans Saints.
Lakers 1st-Round Draft Pick Floated as Trade Piece
The Los Angeles Lakers are off to a fast start. Could it be time to weigh trading away some young pieces to boost the rotation? The post Lakers 1st-Round Draft Pick Floated as Trade Piece appeared first on HEAVY.
'Not a one-person job:' Bernardsville explores exit from Bernards Health Department
BERNARDSVILLE - Concerns about costs have led borough officials to consider cutting off decades-long services from the Bernards Township Health Department and switching to the Somerset County Health Department.
Browns injury update: Is Denzel Ward playing against the Titans?
The Browns will enjoy the presence of their top cornerback in Week 7.
Lakers’ Injury Report Rules Out Two Players for Jazz Game
Is Walker Kessler available in his return to Utah?
Kings' Veterans Praise Rookie Acuff After 33-Point Showing
The Sacramento Kings are yet to get a win, but Darius Acuff Jr. looks like the high-octane guard that the franchise so desperately needs. Coming off a 33-point outburst, how will Acuff play against the Memphis Grizzlies?
Memorial Health celebrates staff with trunk-or-treat
Memorial Health went all out for its annual trunk-or-treat event, celebrating team members and their families.
Texas opens as heavy favorite against Mississippi State
The Longhorns are three-score favorite as they welcome the Bulldogs to Austin.
Buccaneers vs. Panthers Week 7 inactives: Baker Mayfield returns
The Tampa Bay Buccaneers are set to take on the Carolina Panthers Sunday afternoon in a crucial NFC South matchup at Bank of America Stadium in Charlotte. Tampa Bay received some encouraging news ahead of kickoff as quarterback Baker Mayfield is officially active and will start after missing the previous three games with a dislocated […]
Giants at Texans live game discussion for Week 7
We, who are about to watch Texans football, salute you.
Browns Week 7 inactives: Who's in, who's out?
The Browns are the healthiest they have been in some time as they take on the Titans in Week 7.
Republican responds to AI video in Fort Bend County political battle
Fort Bend County has seen plenty of controversy at its highest levels.
Chivu: “The boys gave everything right to the end”
Cristian Chivu wasn't the only one who couldn't bear to watch Zielinski's decisive penalty. The Inter coach bent over on the touchline, looking away as the midfielder stepped up to take it. When the b...
Game Time Thread: Juventus vs. Lecce
MATCH INFO When: Sunday, Oct. 25, 2026. Where: Stadio Via del Mare, Lecce, Italy. Official kickoff time: 6 p.m. local time in Italy and across Europe, 8 p.m. in the United Kingdom, 1 p.m. Eastern time, 12 p.m. Central time, 10 a.m. Pacific time. (Please note that the fall time change in Italy goes into effect on Sunday, […]
Packers Lose Defensive Captain Just Before Massive Showdown With Lions
Green Bay Packers defensive captain Zaire Franklin has been ruled out against the Detroit Lions, leaving Green Bay without both starting linebackers.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Texas Tech Leads 'Bad' Week 8 for Big 12 Unbeatens
The Red Raiders’ playoff dreams hit a wall in Cincinnati as sloppy play and missed opportunities ended their unbeaten run. The Big 12 race is now more open than ever after surprising finishes elsewhere.
Jennifer Hawks explains why she should be California's State Treasurer
Jennifer Hawks, a candidate for California state treasurer, shared her qualifications and vision for the office in an interview on California Politics 360.
Timeline of the Capitol Annex project
Ashley Zavala looked back at the decade-long process of building the new offices for the governor and state lawmakers.
Robinson, Baker have tough talk about the offense
Robinson, Baker have tough talk about the offense
Mystery Ohio news site boosting Ramaswamy's Amy Acton ad tied to California GOP non-profit
As Ohio Republican gubernatorial candidate Vivek Ramaswamy came under fire for releasing an attack ad featuring his Democratic competitor Amy Acton's estranged mother, a mysterious news site was runni...
Brazil votes in a tense Lula vs. Bolsonaro runoff with U.S. influence over Latin America at stake
The election pits the left-of-center veteran politician Lula against Bolsonaro, an ally of U.S. President Donald Trump and the son of imprisoned former President Jair Bolsonaro.
Evaluating DJ Herz After Bouncing Back from Injury with Nationals
After making his first MLB appearance in nearly two years, what should the Washington Nationals expect from DJ Herz in his third season with the organization?
Micron Just Revealed a New Business Strategy. That Change Makes It a Screaming Buy.
Micron is changing more toward contracts, rather than letting the open market dictate pricing.
PS5 Answers 'Bleakest' Month with a 22% Upswing in Sales
How much does the enthusiast discourse matter?
Mavericks 'Very, Very Confident' in Rookie PG Behind Kyrie Irving
Spanish sensation Sergio de Larrea shined with 21 points against San Antonio, proving he can anchor the rotation while Dallas carefully manages Kyrie Irving’s heavy workload.
NFL Trade Deadline Could Dramatically Change The AFC South Landscape
With top stars from the Titans, Colts, and Jaguars hitting the trade block, Houston’s rivals could strip their rosters of veteran talent to fuel a mid-season rebuild.
Preview
The Men's First Team are back in Serie A action, this time heading south to face Lecce in Puglia.The Serie A Matchday 8 clash is set to take place at the Stadio Via del Mare at 18:00 CET on Sunday, Oc...
Halifax Health Sees 19 Biketoberfest-Related Injuries in 2026
With Biketoberfest 2026 having ended on October 18, Daytona Beach’s Halifax Health Medical Center announced the statistics on injuries related to the event. 19 patients were treated for injuries …
17 Celebrity Transformations That Left Fans Doing A Double Take
From Avril Lavigne's “soft makeup era” to JoJo Siwa’s “clean girl” aesthetic, these wild celebrity transformations will leave you gagged.
31 'Brooklyn Nine-Nine' Memes That Would Win a Halloween Heist and Become the Ultimate Detective/Genius
These memes are noice!
Nick Nurse: “Jaylen Brown is obviously very good. He …
Nick Nurse: “Jaylen Brown is obviously very good. He …
Hints About Why Sabres Missed Connor Hellebuyck
The fact that the Buffalo Sabres missed out on Connor Hellebuyck could linger painfully for a while if the goalie play in Western New York doesn’t improve in a hurry. It’ll hurt all the more because the reports over the summer indicated that for at least a time, the Sabres were the frontrunners to pull […] The post Hints About Why Sabres Missed Connor Hellebuyck appeared first on HEAVY.
Liverpool host Brighton; Man Utd take on Bournemouth in PL
2026-10-25T13:33:41ZA rundown of today's games...2pm kick-offs:Liverpool vs BrightonManchester United vs BournemouthHull City vs BrentfordCrystal Palace vs Newcastle4:30pm kick-off:Sunderland vs Leeds...
Ranking Ohio State’s remaining games from easiest to hardest
With Julian Sayin out indefinitely, Ohio State’s final five games will define their playoff hopes. Here’s how those opponents rank, from easiest to toughest
NFL Week 7 expert picks, score predictions: Packers at Lions
Green Bay Packers vs. Detroit Lions NFL Week 7 expert picks from the Pride of Detroit staff.
Saints vs. Steelers in Paris: Week 7 game chat
The Saints face the Steelers in this Week 7 matchup. Join us here for the game!
Physician Mental Health and Health System Privacy: Why Doctors Avoid Their Own EHR
In most organizations the default access model was built for patient care, not for protecting colleagues. A nurse on another unit, a resident who rotated with them, a department administrator: any of them may technically be able to open the record, even when policy says they should not.
Open Thread, Sunday, October 25: How we doing today, folks?
Your daily source for off topic chatter with the MMA Mania faithful.
Full injury report for Sunday's Clippers vs. Thunder matchup
Full injury report for Sunday's LA Clippers vs. Oklahoma City Thunder matchup.
One Underrated Timberwolves Wing Gets High Praise From Chris Finch
Terrence Shannon Jr. is shaping up to be one of the Timberwolves' sneakiest threats.