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Dan’s Daily: Caps’ Trade Cost; Draft Rankings; Penguins Money
The fears and concerns over recent reports that the Penguins have a budget different than the salary cap are founded, […]
SLC, SEG Still Negotiating Key Details Over Future of Entertainment District
Two years after the City Council told Smith Entertainment Group it would have to earn staff-level design review, the company's draft agreement for the Downtown district asks for it, and for much more.
PayPal Q3 Earnings Top Estimates. Revenue, Merchant Volume Miss.
Earnings unexpectedly rose, but the payments giant missed on other key metrics.
CBS shares Iowa football bowl projection after Minnesota loss
After dropping its second game of the season, who does CBS Sports project Iowa to meet in a bowl game? And where might the Hawkeyes head?
iPhone 18e Could Get Two Key Upgrades While Keeping 60Hz Display
Apple's upcoming iPhone 18e model will retain a 60Hz display but could gain an upgraded front-facing camera, according to the leaker known as "Digital Chat Station". In a new post on Weibo, the leaker said that the device will feature a 6.12-inch OLED display using low-temperature polycrystalline silicon (LTPS) technology, the A20 chip, and a single 48-megapixel rear camera. They were less definitive about the front-facing camera, saying it could be upgraded to 24 megapixels.
How the Nashville Predators book musicians for NHL games
From Whiskey Jam discoveries to Keith Urban appearances, a look at the team behind Bridgestone Arena's live entertainment.
Inside the new NYU Langone CEO’s plans for growth
NYU Langone is planning to build a multibillion-dollar academic medical center on Long Island.
The broccoli-cooking mistake that may reduce its health benefits
Popular preparation methods might be removing key nutrients from this vegetable. Here’s how experts suggest cooking it instead.
Anthropic IPO: AI catastrophe could exceed insurance capacity
The Claude maker’s prospectus also reveals an FTC investigative demand, uncapped indemnities and a $1.5bn copyright settlement its insurance didn’t fully pay for
Delaware wants to let AI run entire companies: what it means for insurers
A new proposed Artificial Intelligence Company raises a multitude of questions for anyone underwriting D&O, cyber or E&O
How Trump’s ‘little detour’ to Iran became a roadblock in the midterm elections
When President Donald Trump launched his war on Iran, he said it would last a matter of weeks.
Yeva Margaryan: Journal of Breakthroughs in Medicine and Science Reaches Key Pre-Launch Milestones
Yeva Margaryan: Journal of Breakthroughs in Medicine and Science Reaches Key Pre-Launch Milestones / Alex Adjei, cancer, David Kerr, Fatima Cardoso, James
Principal’s small business benefits arm posts 10% sales growth in a softening market
Specialty benefits loss ratio holds below target range as Beam Benefits adds its first customers
Cincinnati Financial’s personal lines new business falls 40% through three quarters
Carrier cites discipline over volume as catastrophe losses bite and competition stiffens
One Dose of Experimental Antibody Kept HIV-Like Virus in Remission For 4 Years in a Monkey
"May be a surprisingly effective route to HIV cure."
Jay-Z picks himself to headline the Super Bowl halftime show at SoFi Stadium in Southern California
Jay-Z will headline the Super Bowl halftime show on February 14 at SoFi Stadium in Inglewood, California.
Is There Hope for Mike McDaniel’s Offense?
With Joe Alt and Ladd McConkey potentially returning after the bye, Mike McDaniel’s offense could finally begin to show its potential. However, getting healthy is only part of the equation. McDaniel must make adjustments and turn improvement into points and wins.
OpenAI Science Discoveries: 3 Claims, ETH, QCD [2026]
OpenAI science discoveries: a claimed ETH disproof, Kakeya proof and QCD existence proof, with academic shepherds. What is verified so far.
$50B rural health fund delivers for Ohio
Rural communities have always been central to Ohio’s strength. From the farms that feed our nation to the small businesses that sustain local economies, these communities represent the hard work, resilience, and determination that define the Buckeye State. Yet for too long, the health care systems serving them have struggled with workforce shortages, financial pressures […]
Two key Pistons questionable for road contest against Knicks
Due to injuries, two key Pistons players are questionable for Tuesday's road game against the Knicks.
Illinois man charged with mailing white powder to members of Congress
Court records show a 37-year-old Illinois man is charged with sending threatening letters to members of Congress containing a white powder, including one with a note reading “HAH enjoy the gift.”.
Detroit council member’s inquiry into West Village small businesses sparks debate
What payroll can tell you about your business
A small business owner has a decision to make. Overtime has climbed for the third month in a row, and the team is stretched. Adding another employee could
Common Sense from a Prestige Science Journal? Yes, Believe It
Good on the editors for pushing back against the subversive notion that a machine can be the moral equivalent of a human being.
CopperPoint completes $84 million General Indemnity Group deal to build national surety business
The Arizona workers’ comp specialist now owns a surety carrier and a digital bond platform licensed in all 50 states, and says it is adding capital to grow the business.
Trump has made transactional promises in roughly half of states holding key Senate contests
President Donald Trump kicked off his general election push by making voters a highly controversial offer. Now he’s gone quite a bit further — and more localized — with his quid pro quos.
Punahou Alumni Healthcare Spotlight Connects Students with Industry Professionals
Punahou hosted its 11th annual Alumni Healthcare Spotlight on October 14, bringing together alumni healthcare professionals and current students. A student committee helped plan the event over the last several months. The evening kicked off with a keynote address in Cornuelle Hall by Dr. Sam Shomaker, dean of the John A. Burns School of Medicine (JABSOM) at University of Hawai’i. He was introduced by Punahou trustee Dr. Doug Kwock ’83. Student attendees then pivoted to small-group breakout sessions, where they […]
New Project Lets Nintendo Switch Games Run Natively on Apple Silicon Macs and iPhones
An open-source project called nxnative lets Nintendo Switch games run natively on Apple Silicon, without an emulator in between. Built by developer seedds, the tool takes a user's own game files and prod.keys and turns them into an app for iPhone, iPad, or Mac. YouTuber Andrew Tsai put it to the...
Equities end higher as Anthropic’s IPO filing buoys AI stocks
Anthropic's IPO filing lifts us stocks and AI-related shares amid a week of key economic data and corporate earnings reports.
ABI keynote: AI should expand human potential, maintain vitality
Organizations should use artificial intelligence to automate routine tasks and stop unnecessary work while protecting human judgment, creativity and experience, Seth Mattison said during his keynote address at the Iowa Association of Business and Industry’s Manufacturing Conference. Mattison is the founder of FutureSight Labs, where he consults on talent management, change and innovation, leadership and…
Brazilian election sends US progressives into online fever as key irregularity stokes result uncertainty
Lula's Brazil election victory sparked celebration from U.S. progressives like Alexandria Ocasio-Cortez, but a last-minute voting extension drew sharp criticism.
First 48 hours: What ransomware attack taught family business about cybersecurity, trusted partnerships
"There was never a question of who I was going to call." When this family business got hit with a cyberattack, it put key steps in motion.
A guide to the key ballot measures voters will decide on Election Day
When Americans cast their ballots in this year’s midterm elections, they’ll not only be picking who represents them in Congress, but also weighing in on a range of topics that could change their state laws and constitutions.
The science of fear: Why some love to be scared, while others hate it
Do you enjoy the thrill of scary movies, haunted houses, and Halloween decorations that jump out at you? Why do some people love to be scared and others simply hate it? Experts say part of the answer begins deep in our brain.
7 Numbers That Explain Anthropic’s Business
We broke down the A.I. company’s key figures, which give insight into the health of its business, its future plans and who’s in charge.
VIRAL VIDEO: League officials ask 3-year-old Florida soccer star, family to leave field, saying child ‘played too well’
A viral video with more than 4 million views posted over the weekend shows a 3-year-old soccer prodigy, Nevada, scoring goals against other children on his i9 Sports soccer team in Winter Park.
Sports equinox on tap with MLB, NFL, NBA, WNBA and NHL all in play at the same time Monday night
If you love sports, it's tough to beat Monday night.
Sports equinox on tap with MLB, NFL, NBA, WNBA and NHL all in play at the same time Monday night
If you love sports, it's tough to beat Monday night.
How Eaton’s (ETN) Data Center Business Complements Amphenol’s AI Infrastructure Opportunity
Burke Wealth Management, an investment management company, released its “Focused Growth Strategy” Q3 2026 investor letter. A copy of the letter can be downloaded here. The fund delivered strong results in the third quarter of 2026, benefiting from a sharp recovery in enterprise software and solid corporate earnings amid continued market volatility. The composite returned […]
Small-business owner shares lessons on passion, research & earning customer trust
Cantrece Jones founded Acuity Design Group in 2008 and opened Aura Plant Studio more than four years ago. She said the businesses have grown gradually, with the plant shop expanding into commercial installations and event rentals as well as retail.
Key Israeli health committee faces tough choices as funding increase stays flat for fourth year
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Google Brotli flaw exposes cloud environments at scale
90% of cloud environments have resources exposed by the Google Brotli flaw as patches roll out unevenly across key platforms. See what risks remain
Key West Chamber of Commerce showcase connects business & community
The Key West Chamber of Commerce’s 37th annual Showcase of Key West Businesses took place Oct. 14 at the Casa Marina, sponsored by Mount Sinai Florida
VIRAL VIDEO: Winter Park 3-year-old soccer star, family asked to leave field after saying child ‘played too well’
Lions fan carries game ball from Green Bay to Detroit in support of families affected by cancer
Lunin: “Discipline, attitude and determination were key”
Real Madrid backup goalkeeper Andriy Lunin talked to the club’s media after starting in Madrid’s 2-1 victory at the Camp Nou. “Discipline and attitude were key because Barcelona had more possession. Also, the determination because playing away is tough, and today these three points were important because we all knew how things stood. Teamwork was […]
6 citizens sue Trump, saying media ban deprives them of news as audience stakeholders
A new lawsuit against President Donald Trump's media ban stakes a claim for the public itself.
Eric Bauza, modern voice of Looney Tunes characters, dies at 46
The modern voice of Looney Tunes has died.
Eric Bauza, modern voice of Looney Tunes characters, dies at 46
The modern voice of Looney Tunes has died.
LIVE: City launches ‘Jacksonville Food Plan’ to increase access to healthy, affordable food
Jacksonville will launch its first food plan Monday, introducing a framework to improve access to healthy, affordable and nutritious food across the city.
Lindsay Lohan revisits key ‘Mean Girls’ filming location on set of new movie
Lindsay Lohan held a ‘Mean Girls’ reunion with director Mark Waters on the set of their new movie ‘Return to You,’ which is filming at the original Heron house used in the 2004 teen comedy.
SCC To Host Modern Hair Care Science: From Follicle to Formulation
The majority of the program focuses on formulation strategies for key product categories including shampoos, conditioners, styling products and scalp treatments.
AI chatbots can be a valuable health resource for older adults – if they embrace ‘informed skepticism’
AI can help you navigate health information, but evaluating the credibility and quality of responses is key.
Barack Obama calls for basic decency in politics at Ohio rally
Former President Barack Obama campaigns in Ohio, warning against political divisiveness and calling for basic decency. The panel discusses the impact of his message on key midterm races in the heartland.
Pioneering industrial band Ministry is done. Take it from founder Al Jourgensen: 'It's time to go'
Ministry, the pioneering industrial rock band that paved the way for acts like Nine Inch Nails, is calling it quits after 45 years.
In his own words: Trump on gas prices and energy costs since launching the war with Iran
Since launching the war with Iran nearly eight months ago, U.S. President Donald Trump has struggled to quell soaring energy costs, undermining Republicans’ attempt to keep control of Congress in the midterm elections next week.
Healthwatch: Dietitian highlights health perks of pumpkins
A pumpkin isn’t just a fall decoration to set out on your front porch. The seasonal squash can also be a healthy addition to a variety of meals.
‘Astronomical’ Arab turnout could reshape Israeli politics in key election
Netanyahu’s opponents consider unprecedented alliances to keep him out of power
Student-loan borrowers' key midterms issue: affording higher bills
Over 10 million student-loan borrowers are behind on payments. Some are hoping the midterms will prompt policy change to protect those in default.
Singer Chris Brown to be sentenced over bottle attack at a London nightclub
Grammy-winning singer Chris Brown is to be sentenced Monday over brawling at a London nightclub in 2003.
Caribbean seeks reparations and questions role of monarchy before King Charles III visits
The royals are coming, and the Caribbean wants to be heard.
Palisades setbacks put nuclear safety culture in the underwriting spotlight
A regulator's warning over a fearful workplace at Michigan's restarting reactor lands just as data-center demand pulls more insurers toward atomic risk
Amynta completes agribusiness push with Southern States acquisition
The deal adds a more than 70-year-old MGU and an exclusive reciprocal distribution arrangement to Amynta’s growing specialty platform
Shares fall in Asia after a decline on Wall Street, and oil prices fall more than 1%
Shares are mostly lower in Asia after a retreat on Wall Street, while oil prices have fallen more than 1%.
A Healthy Balance Between Rigor and Mental Health
Many students of Irvington High School typically start their own nonprofits, strive to have 4.0 GPAs and more extracurriculars than can be counted on the fingers. This is typically seen as the “key” to accomplishing an acceptance to a prestigious university, creating a rigorous and competitive environment where students tend to prioritize academic excellence over...
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo.
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo.
Health network adding helicopter in rapid Pennsylvania expansion
WESTMORELAND COUNTY, Pa. (WHTM) — Not long after they acquired five Pennsylvania hospitals, a health system will soon launch an air medical helicopter in the Keystone State. WVU Health System…
Health network adding helicopter in rapid Pennsylvania expansion
WESTMORELAND COUNTY, Pa. (WHTM) — Not long after they acquired five Pennsylvania hospitals, a health system will soon launch an air medical helicopter in the Keystone State. WVU Health System recently...
Raptors to miss Kawhi Leonard on Sunday night
The Raptors will be without a key piece of their lineup on Sunday night.
Germaphobe primates want to avoid getting sick, too
Some monkeys become significantly more cautious about food sources that appear contaminated after experiencing deadly outbreaks of disease.
The Politics of Heaven ~ The Imaginative Conservative
The key to understanding Thomas More’s generous dedication to the real but limited good he could do on earth is, as Frank Mitjans makes clear, that More’s constant contemplation of God was the source of his boundless care for the souls surrounding him. Thomas More’s Vocation, by Frank Mitjans
Dodgers’ De Paula Faces Key Defensive Test
Josue De Paula impressed the Los Angeles Dodgers with his bat during his major-league debut. Can he do the same with his defense?
Ravens lose standout rookie to injury against Bengals
The Baltimore Ravens have lost a key rookie to injury, forcing another change up front against the Cincinnati Bengals.
Alaska Democratic Senate candidate Mary Peltola and her family suffer minor injuries in car crash
Alaska’s Democratic Senate candidate Mary Peltola and her family suffered minor injuries Saturday in a car crash while driving to a campaign stop, her campaign said.
Projections for Cleveland Guardians’ Arbitration Eligible Players
The Cleveland Guardians have several key players arbitration-eligible this offseason.
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.
New Trump housing order targets mortgage and title insurers
A White House plan to pull private mortgage insurance off loans sooner, and to let refinancing borrowers skip the lender's title policy, affects two insurance lines that say they already help keep costs down
China Star Entertainment (SEHK:326) Stock Looks Richly Priced As Its 8.6x Run Continues
China Star Entertainment has logged very strong multi year share gains, so the key issue now is whether the current price can be supported by the value of assets on its balance sheet. For anyone looking at the stock today, the immediate question is how that share price lines up against its book value. Over the past 3 years the stock has returned about 8.6x. This puts a lot of weight on whether the underlying equity in the business justifies this kind of move when you compare it with the...
Senate rivals seek support from Alaska Native voters
The major candidates in Alaska’s U.S. Senate race are both casting themselves as strong voices on Alaska Native issues as they seek support from the key constituency ahead of the Nov. 3 election
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race
Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.
Blanche says Trump isn't trying to meddle with Alaska election results by suing over Senate race
Attorney General Todd Blanche is defending the Trump administration’s lawsuit to block certification of Alaska's Senate results if incumbent Republican Dan Sullivan loses the race.
Liverpool 2, Brighton 0 – Match Recap: That Was Actually Fun
A look back at the key moments in Liverpool's great victory over Brighton in Premier League action.
Googlebook is getting AAC Bluetooth audio and key fixes for Cast My Apps
As we talked about earlier this week, every brand-new platform goes through growing pains right out of the gate, and Googlebook OS is no exception. While we've already seen Google step up to...
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Babcock Singles Out Oiler After Ugly Loss To Maple Leafs.
Mike Babcock called out one player in particular after a 7 - 2 thrashing against the Leafs.
Some Thoughts About Ron Duguay
Dear, departed Ron Duguay was not anything like his playboy image.
Science Snapshots: October 25, 2026
Three key science updates in one minute: Starry Night’s dawn matched to Jul 22, 1889; cold boosts lifespan via BH2/BH4; cluster similar-buildings cools cities.
Week 7 Early Games Open Thread
The only games I’m really keyed in on are the Steelers and Texans both losing to the NFC team and then decided which team between the Bengals and Ravens are the bigger threat to Denver’s future playoff seeding arrangement. Here are the games we have to watch today before the Denver Broncos take on the […]
Iowa Football Was Never Truly A CFP-Caliber Team. The Loss To Minnesota Proved It
The Hawkeyes had plenty of momentum after the Washington game, but there's just too much inconsistency right now. Everything fell apart against Minnesota.
She voted for Trump every time. Then came cancer and the bills
Cindy Banda faces mounting medical bills after battling breast cancer.
She voted for Trump every time. Then came cancer and the bills
Cindy Banda faces mounting medical bills after battling breast cancer.