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Results for " Helped " 1,332 found 🔀 AI-powered Shuffle

Alan Osmond, the eldest member of the Osmonds, has died at 76

He helped write some of the Osmond Brothers' biggest hits, including "One Bad Apple," "Crazy Horses" and "Are You Up There?"

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Apr 21 • 12:51 PM EDT • Entertainment • spectrumlocalnews.com
Glowing ring of plankton surrounding New Zealand islands linked to deadly underwater plateau

A recent satellite photo captured a gleaming halo of phytoplankton encircling the remote Chatham Islands. The stunning sight is the result of a hidden underwater structure, which has also helped kill hundreds of cetaceans.

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Apr 21 • 3:00 AM EDT • Science • livescience.com
Sports Take: Top 5 Baylor WBB players of all time

From foundational stars to generational icons, Baylor women’s basketball has produced no shortage of greatness over the past 25 years. These five players did more than fill up stat sheets; they helped shape the standard of excellence that defines the program.

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Apr 20 • 11:31 PM EDT • Sports • baylorlariat.com
Coachella: Madonna, Justin Bieber, and all the big winners from Weekend 2

A surprise appearance helped Justin Bieber turn around his festival performances.

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Apr 20 • 3:35 PM EDT • Entertainment • yahoo.com
After a year of turmoil, cancer researchers see promising signs for mRNA vaccines

The mRNA-based Covid vaccines helped blunt the impact of the pandemic but also sparked political backlash that has threatened to slow or derail dozens of potential cancer treatments. Now there are signs that the mRNA train is still on track.

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Apr 20 • 7:00 AM EDT • Health • cnn.com
How a Sault High graduate helped shape WWII radar and American science leadership

Bernie Arbic will use a PowerPoint presentation at Bayliss Public Library Thursday, April 23, at 6 p.m. to trace the life of DuBridge, from his days at Sault High School to national prominence in science

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Apr 19 • 2:00 PM EDT • Science • sooleader.com
Felt lost moving back to my hometown at 30; new activity helped

I struggled to adjust to living in my hometown after spending years abroad. Discovering Brazilian jiu-jitsu helped me build community and confidence.

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Apr 19 • 8:15 AM EDT • Business • businessinsider.com
A Look At AMC Entertainment Holdings (AMC) Valuation After Record Easter Trading And Odeon Refinancing

AMC Entertainment Holdings (AMC) has drawn fresh attention after reporting record combined global admissions and food and beverage revenue over the five day Easter weekend, helped by the release of THE SUPER MARIO GALAXY MOVIE and strong attendance across its theatres. See our latest analysis for AMC Entertainment Holdings. The recent record Easter trading, together with refinancing at Odeon and fresh attention from B. Riley, has coincided with sharp short term share price momentum. This...

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Apr 19 • 6:03 AM EDT • Entertainment • finance.yahoo.com
‘The Oscar of science’ awarded to scientists behind genetic treatment that restores lost vision win

Breakthrough prize in Life Sciences awarded to team who developed Luxturna therapy, which helped a patient see their child’s face for the first time

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Apr 19 • 2:00 AM EDT • Science • theguardian.com
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Nvidia's once-tight bond with gamers is cracking over AI, 'and that breaks my heart'

Gamers once helped save Nvidia from bankruptcy. Now they feel left behind as the memory crunch drives focus to AI chips and DLSS 5 disrupts game design.

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Apr 18 • 8:00 AM EDT • Technology • cnbc.com
Russia Signals Pullback in Business Support as Budget Strains Mount

Russia’s government warned it will scale back new support for businesses as mounting fiscal pressures limit its ability to sustain the stimulus that helped drive recent economic growth, Economic Development Minister Maxim Reshetnikov said Friday.

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Apr 18 • 3:09 AM EDT • Business • themoscowtimes.com
Zelda taught me the importance of play – and has helped me deal with work, parenting and grief

I initially dismissed the Wid Waker’s cartoonish visuals as juvenile. Then I fell in love with the game sense of joy and have tried to carry it into all aspects of my life

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Apr 18 • 2:00 AM EDT • Technology • theguardian.com
Report: Colorado incentives drive 143 business expansions and 42,000 jobs

Colorado's incentive programs helped attract 143 companies, creating over 42,000 jobs and $4.8 billion in wages, boosting the state's economy.

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Apr 17 • 6:13 PM EDT • Business • coloradobiz.com
Anabaena Learns A New Trick - Cyanobacteria Surprise Scientists With Evolutionary Shift

Photosynthetic bacteria helped shape Planet Earth.

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Apr 17 • 12:41 PM EDT • Science • astrobiology.com
Democratic Senate hopefuls put California cash in the bank

California donors helped Democrats in key Senate races outraise their Republican opponents, according to latest campaign filings.

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Apr 17 • 12:14 PM EDT • Politics • latimes.com
UF Health Florida Recovery Center director dies: ‘He truly brought FRC to life’

Dr. Scott Teitelbaum helped hundreds through addiction recovery

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Apr 17 • 12:11 PM EDT • Health • wcjb.com
UNC Hussman offers new sports play-by-play class | UNC Hussman School of Journalism and Media

This story, written by UNC Hussman alumna Caroline Daly ’24, was originally published on unc.edu. The UNC Hussman School of Journalism and Media has a new, hands-on class available for students interested in sports careers. Students in “MEJO 390: Sports Commentary and Play-By-Play” can call live radio broadcasts for Carolina sporting events, streamed live on the Go Heels website. This spring, 11 students are calling mostly softball games to gain experience and learn the preparation needed for a successful broadcast. The class is capped at a small number to provide consistent, individual feedback. Matt Krause, the radio voice of Carolina women’s basketball, teaches the class to help students sharpen their skills, using his experience with the Tar Heels and calling games for ACC Network and ACC Network Extra. “There is no substitute for live reps, and that is the only way you get better. The classroom component teaches you how to get better, but going about that requires sitting in that chair, making mistakes and being able to know your broadcast is going somewhere,” Krause said. “These students are doing real live games, and they will have tape where if they want to pursue this. They will have ready-made demos to send for jobs. Being able to utilize all the resources of UNC, GoHeels Productions and the Carolina Athletics brand and create these opportunities for students is really impactful.” In the class, students learn fundamentals like how to announce starting lineups for different sports and how to conduct research before games. Krause has led the class in mock preparation exercises, looking at game charts with information about the different teams and players that they can refer to at pivotal moments during the game. Krause and the students then critique each other, listening to clips from the past week to find ways to improve. It’s a rare class without a slew of quizzes or assignments. Their main tasks are calling games and making a portfolio or demo reel of their best calls at the end of the semester, all with the goal of being ready to step into similar roles after graduation. Laible live streams her coverage on the GoHeels website. Calling a live game while broadcasting her coverage allows her to get hands on experience. (Jon Gardiner/UNC-Chapel Hill) Junior Anna Laible ’27 wished for a class just like this. Her first year at Carolina, she interned with the Coastal Plain League, where she was introduced to play-by-play for baseball. “I enjoy the challenge and uncertainty of each game being different because each sport looks a little different,” said Laible. “Each game is different — not just with teams but what could happen with certain records being broken or random trends. That’s what I enjoy most.” She wanted more opportunities for reps during college to prepare for a career after Carolina, so she pitched an idea for the class to Livis Freeman ’99, distinguished associate professor of sports communication. Laible and Freeman reached out to GoHeels Productions for a partnership and then connected with Krause. “This is how at UNC Hussman we separate ourselves: Our students go into the field ready,” said Freeman. “The biggest compliment we get it is when our students start their careers, they don’t need any hand-holding.” Laible calls a Carolina softball game at Kessing Stadium – after pitching the idea to Hussman faculty. Her interest in sports commentary allowed her to apply her interest as she attends Carolina. (Jon Gardiner/UNC-Chapel Hill) Laible is now a student in the class, which has helped her strengthen her skills and deepen her passion for the field. The goal is to expand to other sports like soccer, lacrosse and field hockey. “The hands-on experience I’ve gotten here is invaluable. I’ve loved the classes and professors because they’ve taught me a lot, but it’s also the things outside of class, too, that have helped me grow,” said Laible. “Since being at UNC, I’ve grown a lot in the versatility, from doing writing to production and commentating. UNC Hussman and Carolina have given me the ability to be strong and well rounded.”

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Apr 16 • 9:07 AM EDT • Sports • hussman.unc.edu
Is Base Stealing a Science or an Art Form? RI's David Earl Lopes…

Former Major League Baseball players Dusty Baker, Dave Stewart, and Jerry Royster helped celebrate David Earl Lopes’s homecoming this past Wednesday.…

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Apr 16 • 2:27 AM EDT • Science • golocalprov.com
Influencer who helped expose Swalwell scandal reacts to new investigations
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Apr 15 • 6:32 PM EDT • Politics • cnn.com
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Red Sox 9, Twins 5; Boston swings to salvage finale

The Red Sox broke out the bats in need of a response from Tuesday’s shutout loss. A big day for Trevor Story (5 RBIs) helped Boston earn a 9-5 win over the Minnesota Twins. The Red Sox avoided the sweep against the best team in the American League so far. Here are three takeaways from […]

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Apr 15 • 5:53 PM EDT • Sports • sports.yahoo.com
Alex Vesia emotional after save with healthcare workers who helped family through daughter's death in stands

Alex Vesia, who lost his infant daughter in October, was admittedly emotional after collecting a save on healthcare appreciation night, where staff who helped him were in attendance.

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Apr 15 • 2:42 PM EDT • Health • foxnews.com
Rader Health Clinic Nurse Receives Life-Saving Award

A Rader Health Clinic nurse was recognized for her extraordinary actions in 2025 that helped save the life of a teenager during an incident at the Pentagon City Mall.

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Apr 15 • 8:00 AM EDT • Health • dvidshub.net
Dodgers Beat Mets Behind Yoshinobu Yamamoto's Strong Outing

Yoshinobu Yamamoto's 7 2/3 innings helped the Los Angeles Dodgers take the series against the New York Mets.

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Apr 15 • 12:20 AM EDT • Sports • sports.yahoo.com
I'm 87 and lift weights, do yoga, and cycle weekly

Peter Brenner, 87, says cycling, yoga, weights, and a simple diet have helped him stay fit after a childhood marked by war, loss, and hardship.

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Apr 14 • 10:29 AM EDT • Business • businessinsider.com
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How This CU Denver Student Discovered His Passion for Politics

At 12 years old, Mario Quinones Rabelo wasn’t obsessing over video games or watching content creator MrBeast on YouTube. That’s how old he was when his Campus resources, helpful advising, and valuable community partnerships helped this student dream bigger than he ever thought possible.

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Apr 14 • 10:08 AM EDT • Politics • news.ucdenver.edu
Player Grades: Cavs vs Wizards – Tyrese Proctor ends strong

Proctor helped the Cavs finish the season strong.

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Apr 12 • 8:17 PM EDT • Sports • sports.yahoo.com
Sports Quote of the Day: Muhammad Ali's Confident Affirmation

Muhammad Ali had a timeless quote that helped explain why he was so successful.

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Apr 12 • 3:18 PM EDT • Sports • sports.yahoo.com
GSK sees blockbuster potential in targeted cancer therapy after promising early data

British drugmaker GSK's experimental targeted cancer drug Mo-rez has blockbuster potential, its head of oncology research has told reporters, after early data showed the drug helped ​shrink tumors in patients with advanced, hard-to-treat cancers.

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Apr 12 • 10:12 AM EDT • Business • reuters.com
I used Meta's Muse Spark AI to rate my lunch and suggest dinner

Muse Sparks rated my lunch a 7.5 out of 10, told me to watch my sodium intake, and gave me dinner recipes that helped me get rid of leftovers.

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Apr 12 • 9:14 AM EDT • Business • businessinsider.com
‘Euphoria’ has outgrown itself, on screen and off

Everything was different when “Euphoria” premiered in 2019. Now, as the series makes its long-awaited return Sunday, the third and final season of the show is emerging into a drastically different world, both in terms of the story being told on screen and the generation of stars the show helped launch off screen.

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Apr 12 • 9:00 AM EDT • Entertainment • cnn.com
ON THE JOB: “What is the Best Business Advice You’ve Ever Received?

Interviews by Deborah Jeanne Sergeant Sound advice can contribute to your success. We recently asked area business leaders, what was their best advice they’d ever received. Here’s what they said: “The best advice I ever received was from my then –boss, Gerry Church, Fulton plant manager at Miller Brewing Co. He told me that whenever I wanted to discuss a business problem or issue with him, I should also be prepared to offer possible solutions. It’s the difference between being proactive or reactive. It’s also the difference between being a leader or follower. That has served me well in any business relationship I have had since then.” — Stephen Chirello, Owner, Steve Chirello Advertising, Fulton “Someone will always do it for less; they will also take the most effort to service or satisfy and leave you for the next lower price.” — John M. Henry, Owner, Speedway Press, Mitchell Printing, Phoenix Press, Oswego “I’m going to answer this question by turning it around and giving my own advice that is, ‘Always treat every customer as if they were your only customer!’ We are celebrating our 50th anniversary in business this year. We started our business on March 25, 1976. My advice works.”” — Nick Chervinsky, President, Brewerton Pharmacy, Brewerton “’You need to toot your own horn, my grandfather, Howard D. Dice, told me.” — Beth Ann Dice, Women’s active aging and cancer recovery coach, Mission Movement Wellness Studio & Breast Cancer Recovery Studio, Fulton “In the micro enterprise class, they taught, ‘Get a good lawyer, accountant and bank.’ That was over 30 years ago and I still have those three today. I chose good people I could grow with.” — Tony Pauldine, Owner, Anthony M. Pauldine General Contractors Inc., Oswego “From my grandfather; ‘Listen to everyone! You never know where you will get the solution you need.’” — Kevin Dean, Executive director, Oswego County Opportunities, Fulton “‘Preparation is the mother of success.’ My dad always drilled that into my head growing up, and it has helped me avoid a lot of snags in both my personal and professional life. Thanks, Dad!” — Bekkah Frisch, Owner and president, iHeart Holdings, Inc., Fulton “If you don’t take a risk and try, you will never know.” — Justin Taber, Owner, Torbitt’s Service Center, Oswego “Be ready to take a loss.” — Cody Seymour, Manager, Damiano’s Eatery, Mexico “I’ve received so much good business advice over the years. When people are giving you advice, always be curious rather than judgmental. Follow your gut. Doing the right thing is never the wrong thing.” — Dana Decker, Principal owner/broker, Berkshire Hathaway Home Services, Oswego ’Do it and figure it out later.’ It hasn’t failed me yet. Too many people take time to think about doing this and this and this and then the opportunity is over with. If it’s somewhat reasonable — if it’s not something outrageous — do it and figure it out later.” — Jeremy Allen, Licensed real estate salesperson, Acropolis Realty Group, Syracuse “’Try to meet the needs of the customer. Treat them like you’d like to be treated.’ It’s like the Golden Rule says.” — Douglas Dickson, Physician and associate at CNY Foot Surgery and Podiatry Care, East Syracuse “The best piece of business advice I’ve ever received applies to life in general: always be honest. Never overstate your capabilities and always be willing to ask questions. The more specific you can be in any given topic will always lead to a better outcome.” — Tom Fernandez, President, Woodbine Hospitality, Syracuse “As a business owner, the advice would be ‘Don’t overextend yourself. Especially in agriculture, expect issues to come up.’ If something is going right, it’s not true agriculture. This last season, we scaled very hard to field another crew. We got more drones, crew and generators based on projections. This last season hit the ag community hard with a very wet spring. We did 15,000 to 20,000 acres for fungicide and the same for cover crop seeding in 2024. We scaled to 25,000 to 30,000 for 2025. We ended up doing 2,000 for fungicide and 3,000 for cover crop seeding. That’s why that advice was good.” — Rick Jordan, Operations manager, CNY Drove Services, Clinton “’Keep your head down, mind your own business and do the best for your clients that you can do.’ It has a lot to do with my success in working for Galloway Century 21.” — Ed Fayette, New York state licensed real estate agent, Century 21 Galloway, Oswego “’Expand in all ways, always.’ It just keeps you going and keeps you growing.” — Stephen Baier, Licensed real estate person, The Real Estate Agency & Bouck Commercial, Auburn “The best advice is, ‘Your biggest asset you won’t see on the books because it comes from your employees.’” — David Flickinger, Owner, Edible Arrangements, Syracuse “Don’t take things personally when you’re working with the public.” — Leeann Desimone, Manager, Annie’s Hallmark Shop, Auburn “‘Follow up.’ The customer knows that you care about what you are doing and that their opinion counts. Sometimes they might be on the fence about whether they want to use your company. If they’re asking your opinion on things, they feel you are concerned about what you’re doing. They like to be kept in the loop if they’re spending money with you.” — Dorothy Casper, Saslesperson, SweetWoods Memorials, Phoenix “The best business advice I received is ‘Never be the smartest person in the room. Surround yourself with people who are smarter than you.’ That’s how you learn.” — Debbie Bilello, Owner, Virtual Office Solutions, Central Square “’You need to grow your business but you can’t grow too big too fast.’ That’s what we’ve done at Pinnacle Maintenance. We’ve tried to grow but not too fast. Along those same lines, there’s another good piece of advice, ‘Don’t take on more than you can handle because it only leads to a bad name for your business and a bad experience for your customers.’ It goes along the same lines as growing your business slowly and carefully.” — David Wines, Owner, Pinnacle Maintenance, Central Square “Always be on time and do what you say you are going to do.’ I’ve done very well following that advice. Most of my work is referral and I don’t really do any advertising so I have a pretty good customer base. It’s mostly word-of-mouth from satisfied customers.” — Robert J. Fleming, Owner, Bob Fleming Windows & Doors, Brewerton “’Concentrate on your finances, always pay your taxes, and form a team you can depend on. Try to help the community you’re in as much as you can.’ We do all of these all the time here. We give and give and give to the community and the community gives back to us always.” — Susan Bonnet, Co-owner, Bonnet Sales and Service, Central Square “Keep smiling. It brings a positive attitude to the workplace.” — Karin Lindsley, Vice president, DTS Truck Service, Syracuse “‘Customer service above all.’ Following this advice has served us very well.’ — Guy Fox, Owner, Fox’s Discount Parts, West Monroe “The best thing to do is to make sure you’re taking in more money than you’re spending. I wish I could say I’m a good businessman but I have been in business since 1981. I’m not a bean counter but work well with my hands and its’s served me well all these years and I am still in business.” — Matt McGill, Owner, Matt McGill Collision, Brewerton

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Apr 11 • 4:39 PM EDT • Business • oswegocountybusiness.com
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In praise of popular science

As a kid, I was enthusiastically and unreservedly in favor of a manned space program. Our destiny lay in the stars, I figured. Get people out there. We need Star Trek here and now. As I got older, I became rather disenchanted with the idea. Humans are expensive, fragile, and inefficient as space cargo. We could flood the solar system with 100 robotic probes for the price of any single manned mission and get back just as useful data. Besides, it turns out space travel is dangerous. Tusk is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe When it came to the recent Artemis II mission, my cynical side didn’t really see the point. Flying around the Moon and back is literally something we did before I was born, and I once owned a Members Only jacket. Apollo 8 circled the Moon ten times and returned to Earth safely the same month that “Chitty Chitty Bang Bang” was released. What was the point of repeating a feat that far braver people once did with tin foil and slide rules? Yet I’ve surprised myself with how moving I’ve found the Artemis II mission to be. The photos have been stunning. The crew has been professional and engaging. There have been modest but important milestones — the farthest humans have travelled from Earth; the first woman, person of color, and non-American to leave low-Earth orbit; innovations in communication, and more. One thing that really stood out is that this is really NASA at its finest. Not that this is the most important mission they ever pulled off, but they did this in a competent way that celebrated the achievements and kept the crew and the science at the forefront of the project. This wasn’t some billionaire throwing celebrities or cars into orbit as a vanity project — this was a collective effort to send experts in to do a job and come home safely. We don’t see that sort of thing much these days. I’m guessing few people would describe many government agencies as inspiring, but this one counts for me. We’re living through a profoundly anti-science era, in which pathbreaking, lifesaving discoveries like mRNA vaccines are routinely downplayed or even vilified. As I’ve noted previously, this era is something like that of the Red Scare in the 1940s and 50s, in which “egghead” professors were portrayed as out of touch or even hostile to regular Americans. One of the things that helped break that spell was Sputnik — the Soviet communications satellite that demonstrated that the United States was falling behind in crucial scientific research and applications. Its launch triggered a new appreciation for American science and goaded the federal government into supporting research universities and labs. I’m not saying that Artemis is the equivalent of Sputnik, but it potentially reminds people that there’s some value to scientific endeavors and the human faces attached to them. Despite my love for the show “For All Mankind,” I’m far from convinced that there’s any real value to putting colonies on the Moon or Mars that would justify the capital investment and the massive health risks to the astronauts. But sending scientific good will ambassadors on a trip into space once in a while? Bring it. Share

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Apr 10 • 9:54 PM EDT • Science • smotus.substack.com
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Thomas S. Langner, Who Linked Social Ills to Mental Illness, Dies at 102

He helped lead what became known as the Midtown Manhattan Study, which showed that mental impairment is highly correlated with low socioeconomic status.

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Apr 10 • 5:30 PM EDT • Health • nytimes.com
Team IMPACT CEO Krissie Kelleher understands the healing power of sports, teamwork and community

Krissie Kelleher used lessons from her lacrosse career to guide her daughter through surgeries and treatment for a spinal cord tumor. Witnessing how sports helped her daughter heal emotionally and physically inspired Kelleher to lead Team IMPACT, a national nonprofit connecting children facing serious illness with NCAA sports teams. Today, the organization partners with more than 400 schools and 1,100 teams to help kids build confidence, find community and experience hope through teamwork.

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Apr 10 • 7:00 AM EDT • Sports • ncaa.org
Chinese business ‘hired lobbying firm with ties to Donald Trump Jnr’

Lobbying firm Checkmate helped China’s Grand Pharmaceutical Group beat a US national security challenge, public filings show.

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Apr 9 • 7:16 PM EDT • Business • scmp.com
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Dave Chappelle helps keep Ohio radio station rooted in hometown with restored building

Dave Chappelle has helped secure the future of a small-town radio station by funding the renovation of a historic building in Yellow Springs | KMBZ

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Apr 9 • 6:00 PM EDT • Entertainment • audacy.com
Dave Chappelle helps keep Ohio radio station rooted in hometown with renovated building

Dave Chappelle has helped secure the future of a small-town radio station by funding the renovation of a historic building in Yellow Springs | WBEN

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Apr 9 • 6:00 PM EDT • Entertainment • audacy.com
How $2M has helped KC’s Black businesses grow: ‘Represents what is possible’

“We were doing pretty well,” one business owner said. “They just kind of added a little bit more gasoline to the fire.”

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Apr 9 • 4:26 PM EDT • Business • kansascity.com
Chinese business hired lobbyist with ties to Don Jr, then scored a win

A lobbying firm led by one of Donald Trump Jr.'s hunting buddies helped a Chinese company make its case to a U.S. national security watchdog.

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Apr 9 • 3:58 PM EDT • Business • detroitnews.com
How Teach for America Helped Set Up James Talarico’s Political Rise

The prestigious education group is more than a shiny resume item. For the Democratic Senate candidate, it was an incubator for his rapid political ascent.

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Apr 9 • 10:15 AM EDT • Politics • texasobserver.org
Exclusive: Chinese firm hired lobbyists with ties to Don Jr, then scored a win in Washington

A lobbying firm led by one of Donald Trump Jr.'s hunting buddies helped a Chinese company make its case to a U.S. national security watchdog against a U.S. startup that was seeking to have the Chinese firm removed as one of its investors, public filings show.

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Apr 9 • 6:03 AM EDT • Business • reuters.com
Pediatric ICU nurse brings clinical insight to global health policy analysis | Harvard T.H. Chan School of Public Health

Heesu Shin, SM ’26, helped take care of kids at his hospital in South Korea. Now, he’s working to help them on a larger scale through his research.

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Apr 7 • 9:46 AM EDT • Health • hsph.harvard.edu
'He's a throwback': Fernando Mendoza keeps business focus as NFL Draft waits

Fernando Mendoza's passion for finance has helped him become a better football player, he says, as the Heisman winner prepares for the 2026 NFL draft.

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Apr 7 • 6:01 AM EDT • Business • usatoday.com
Earth’s most powerful ocean current didn’t form the way we thought

A colossal ocean current encircling Antarctica—stronger than all the world’s rivers combined—played a far more complex role in shaping Earth’s climate than scientists once thought. New research shows it didn’t form just because ocean gateways opened, but required shifting continents and powerful winds to align. This shift helped pull carbon dioxide out of the atmosphere, contributing to a major cooling event that transformed Earth into the ice-covered world we know today.

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Apr 6 • 8:00 PM EDT • Science • sciencedaily.com
‘Marshals’: All the Details on Riley Green’s Acting Debut

How Luke Grimes helped the country music star audition for the part, plus when his episode airs.

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Apr 6 • 11:10 AM EDT • Entertainment • wyomingnews.com
​Investing in Tomorrow: Strengthening Human Development and Resilience in Ukraine​

Since Russia’s invasion, World Bank support has helped Ukraine sustain essential services by protecting schools, strengthening healthcare, and delivering social assistance to those most in need.

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Apr 6 • 6:54 AM EDT • Health • projects.worldbank.org
Inside the sprawling world of MAGA merchandise

The massive industry has helped President Trump collect millions.

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Apr 5 • 1:00 PM EDT • Politics • seattletimes.com
10 Wickedly Cool Carroll Shelby Cars That Made The Man A Legend

Carroll Shelby was an iconic figure in American automotive culture whose cars spoke for themselves. Here are 10 of coolest car he helped create.

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Apr 5 • 8:45 AM EDT • Technology • jalopnik.com
BWC: N.Y. officers save person suffering mental health crisis from frigid river

Auburn Police Officers Edward Pickard and Lucas Drancsak spotted the person, climbed down a 10-foot wall and ran to shoreline; Pickard entered the water and helped the person to safety

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Apr 4 • 8:00 AM EDT • Health • police1.com
What it's like flying Southwest after all the changes; A-List helped

I hit the spending threshhold on my Chase Reserve card in 2025 to secure free A-List status on Southwest. Now, I wouldn't fly the airline without it.

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Apr 4 • 5:11 AM EDT • Business • businessinsider.com
A Meat Plant Closed in Nebraska. Then Politics Became a Focus for These Latinos

Politically disconnected young men, especially Latinos, helped fuel President Trump’s victory, but in this economy, they could move to unconventional candidates like Dan Osborn in Nebraska.

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Apr 4 • 5:00 AM EDT • Politics • nytimes.com
Meteor impacts may have sparked life on Earth, scientists say

Asteroid impacts may have helped kick-start life on Earth by creating hot, chemical-rich environments ideal for early biology. These impact-generated hydrothermal systems could have lasted thousands of years—long enough for life’s building blocks to form. Scientists now think these environments may have been common on early Earth, making them a strong candidate for where life began. The idea could also guide the search for life on other worlds.

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Apr 3 • 8:00 PM EDT • Science • sciencedaily.com
Sphere Entertainment (SPHR) Is Up 17.4% After Wizard of Oz-Driven Revenue Surge and Global Expansion Plans

Sphere Entertainment recently reported past-quarter revenue growth of 28%, powered by the success of its “Wizard of Oz at Sphere” production in Las Vegas, which has sold more than two million tickets and helped narrow operating losses in the Sphere segment. On the back of this stronger performance, the company is now moving ahead with international Sphere developments in Abu Dhabi and National Harbor, signaling a push to replicate its immersive venue model beyond the US. We’ll now examine...

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Apr 3 • 6:25 PM EDT • Entertainment • simplywall.st
We all need to become better science storytellers. Here’s why and how.

Last week, in a lovely New Haven bar, six people gathered in front of a crowd to tell stories that were somehow related to science and public health. It was magical. One person talked about learning how social determinants of health helped them forgive their mother’s alcoholism. Another shared what it’s been like navigating a dementia diagnosis. Another described their last dinner with their mother before they left Nigeria to come to the U.S. and how that moment, plus the diagnosis that followed, shapes their career goals today. As the Executive Director of The Evidence Collective at Your Local Epidemiologist, I was ecstatic to bring this event, “Science and Storytelling,” to the community surrounding the Yale School of Public Health. Stories are not the default way most people communicate about science and public health. In fact, we are taught to take all the emotion out of data, but that makes it pretty darn boring to everyone else. And if people can’t see themselves in it, feel themselves in it, or influence it, how can we ask them to support it? Why do stories stick? How can we all—from community members to public health scientists—do better? And what are some examples?

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John Elberling, combative S.F. nonprofit housing leader and political power player, dies at 79

The nonprofit leader helped preserve affordable housing in South of Market and shaped San Francisco politics for decades.

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Apr 2 • 10:44 PM EDT • Politics • missionlocal.org
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UCLA women's basketball players say playing other sports helped them

The UCLA Bruins took the court in Phoenix for Final Four practice, then looked back on the fun of playing other sports before choosing basketball.

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Apr 2 • 9:18 PM EDT • Sports • azcentral.com
The hero of the day

The earliest bits of concrete NC State sports memories I have involve Torry Holt and Justin Gainey—1997 felt a little transformative for both sports at the time. Torry helped the football team pull a huge upset in a (nonconference) game at Syracuse to open the ‘97 season; in March of that year, Gainey played every […]

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Apr 2 • 9:00 PM EDT • Sports • sports.yahoo.com
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UConn Health Team Navigates Rare Pregnancy Condition to Deliver Healthy Baby

A rare pregnancy complication turned Andrea Garfield’s journey into a race against time, but early detection and coordinated care at UConn Health helped del ...

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Apr 2 • 7:30 AM EDT • Health • today.uconn.edu
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How A.I. Helped One Man (and His Brother) Build a $1.8 Billion Company

Who needs more than two employees when artificial intelligence can do so many corporate tasks? It’s super efficient — and a little bit lonely.

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Apr 2 • 5:02 AM EDT • Business • nytimes.com
‘The Masked Singer’ Runner-Up Reveals How ‘American Idol’ Experience Helped

Plus, what his son thinks of Pugcasso now.

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Apr 1 • 10:25 PM EDT • Entertainment • kten.com
Artemis II: Arizona science, businesses helped launch new moon mission

Arizona businesses and institutions are playing a crucial role in powering the historic Artemis II launch, and they are also helping out with future lunar missions.

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Apr 1 • 9:20 PM EDT • Science • fox10phoenix.com
Pink slip to ESPN empire: Bill Rasmussen transformed sports viewership

Bill Rasmussen did more than launch a cable network. He helped create the modern sports culture Arizonans now live inside.

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Apr 1 • 5:30 PM EDT • Sports • cronkitenews.azpbs.org
Digital heart twins can guide a lifesaving procedure

The "digital twins" helped doctors spot good targets for heart ablation in 10 patients. Months later, all of them are free of sustained faulty rhythms.

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Apr 1 • 5:00 PM EDT • Science • sciencenews.org
Umpire C.B. Bucknor helped off field by trainers after taking foul ball directly to the face mask

C.B. Bucknor was able to walk off the field after a hard hit to the face mask.

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Apr 1 • 2:44 PM EDT • Sports • sports.yahoo.com
From scrappy startup to tech giant, Apple celebrates its 50th year

Countercultural mythmaking and global corporate dominance have helped the tech corporation sail through criticism.

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Apr 1 • 5:00 AM EDT • Technology • npr.org
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Sorrell celebrates Odyssey Award

Cherokee author Traci Sorrell, whose audio book “Clack, Clack! Smack! A Cherokee Stickball Story” won a national award, celebrated March 23 with Cherokee Immersion School students and teachers who helped

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Mar 31 • 4:00 PM EDT • Entertainment • cherokeephoenix.org
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Airbnb Externship Shows 3L Isabel Samayoa How Legal Strategy Drives Business Growth  - UC Law San Francisco (Formerly UC Hastings)

An externship at Airbnb provided 3L Isabel Samayoa exposure to areas such as contracts, licensing, risk management, and growth strategy, helping her develop the skills and experience to thrive in her future career as a corporate transactions attorney. 3L student Isabel Samayoa reflects on her work with Airbnb’s in-house legal team through UC Law SF’s Corporate Counsel Externship Program. Supported Airbnb’s legal team on commercial contracts, open-source licensing, external partnerships, product counseling, and legal research. Observed how legal advice aligns with business strategy and risk management. Gained exposure to strategic decision-making while preparing for a career in corporate transactions. Q: What did you do in this corporate externship? A: I supported the Airbnb legal team across several functions, including commercial contracts, open-source licensing matters, strategic external partnerships, legal research, real estate matters, internal AI integration, and product counseling. I also gained exposure to corporate structure counseling, litigation, patent counseling, and the company’s broader business strategy. Q: What did you take away from this experience? A: One of the most valuable parts of this experience was learning how a business actually operates. I had never worked on such a large team in the private sector, so I had little exposure to how companies run internally. I learned how lawyers can provide valuable advice to support business goals, seeing how leadership evaluates risk and develops growth strategies. Understanding those priorities allows me to calibrate my legal advice to clients, balancing the client’s goals against the level of risk they are willing to take. Q: How does this experience support your career goals? A: Exploring the anatomy of a successful company was incredibly valuable because I plan to pursue a career as a corporate transactions lawyer. Being in the room with the teams discussing important decisions allowed me to see firsthand the factors that contribute to that success and how lawyers help guide those decisions. Q: Would you recommend UC Law SF and this externship? Why? A: I would absolutely recommend this opportunity. While the team worked on high-stakes matters at a highly successful company, they still created an environment where I felt welcomed. They trusted me with meaningful work and supported me every step of the way. This helped me build confidence in my analytical abilities. Q: What’s your favorite UC Law SF memory so far? A: Some of my favorite UC Law SF memories, aside from my time at Airbnb, involve mentorship. I have benefited from mentorship and have also had the chance to mentor other law students. Watching the students I mentored go on to mentor others has been particularly rewarding. I think mentorship is integral to the legal profession, and it has been inspiring to see that culture thrive at UC Law SF and continue beyond the classroom. The Evidence of Success series highlights UC Law SF students as they share how the College’s opportunities equip them with the experience, skills, and confidence to excel in the legal profession.

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Mar 31 • 11:00 AM EDT • Business • uclawsf.edu
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Royals win home opener over the Twins

KANSAS CITY, Mo (KSNT) – The Kansas City Royals celebrated the 2026 home opener with a strong performance Monday night, defeating the Minnesota Twins 3–1 at Kauffman Stadium. Power from the bottom half of the lineup and a dominant pitching performance helped Kansas City secure the win in front of a sellout crowd of more […]

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Mar 30 • 11:39 PM EDT • Sports • sports.yahoo.com
How Bryson DeChambeau helped Rory McIlroy win the 2025 Masters

Rory McIlroy revealed Bryson DeChambeau's miscue on the 15th hole at the 2025 Masters helped him avoid disaster.

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Mar 30 • 6:00 PM EDT • Sports • sports.yahoo.com
Logan has helped make Columbus a destination city for sports

The head of the Greater Columbus Sports Commission has seen her organization grow along with the Blue Jackets over the past 25 years

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Mar 30 • 2:43 PM EDT • Sports • nhl.com
After a health crisis, AdventHealth’s Community Care helped a Palm Coast man rebuild

When Phillip McKinney thinks about healing, he thinks about music. As a child, he would sit at his grandmother’s piano after church and play the final hymn by ear. It was where he first learned patience and perseverance. Years later, after losing his mother, his health began to decline.

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Mar 30 • 8:00 AM EDT • Health • adventhealth.com
Dell’s CFO is using AI agents to run his finance team—and has helped the AI business go from $0 to $25 billion

David Kennedy discusses the company’s record-breaking year.

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Mar 30 • 4:00 AM EDT • Business • fortune.com
Hornets’ Charles Lee hilariously dismisses ‘not that good’ Derrick White

Hornets HC Charles Lee joked around with Derrick White, whom he helped coach to a title when he was with the Celtics in 2024.

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Mar 29 • 11:07 PM EDT • Sports • sports.yahoo.com
She started a sparkling tea business with her husband; alcohol-free

Natalie Chiu and her husband are both scientists and embrace different ways of thinking. Knowing each other's strengths and weaknesses helped them grow the business.

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Mar 29 • 8:14 PM EDT • Business • businessinsider.com
How Gender Stereotypes Got Written Into Evolution

Feminist biologists have been challenging a flawed fruit-fly experiment that helped harden Victorian stereotypes about sex.

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Mar 29 • 8:00 PM EDT • Science • atmos.earth
Larry Price, former UH football coach and longtime broadcaster, dies

Larry Price, a one-of-a-kind homegrown talent who helped shape University of Hawaii football and local sports media for decades, has died.

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Mar 28 • 12:03 AM EDT • Sports • hawaiinewsnow.com
I started baking every week; helped me snack less, eat better

I decided to bake one new treat per week, and saw many benefits. I found myself snacking less and more intentionally, and my mental health improved.

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Mar 27 • 12:11 PM EDT • Business • businessinsider.com
University of Houston graduates say sports helped bring them together as married couple

When you walk into their Richmond home, photos, merch, Cougar-red everywhere. This is a family built on Houston basketball.

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Mar 26 • 8:44 PM EDT • Sports • abc13.com
Takeaways from Day 1 of CPAC 2026

The movement that helped return President Donald Trump to the White House in 2024 is split over the war with Iran and Trump’s relationship with Israel, the administration’s handling of the Jeffrey Epstein files, fractures among some of its most prominent personalities and more.

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Mar 26 • 7:04 PM EDT • Politics • cnn.com
Reality TV is now a cultural powerhouse. There's no stopping it

The television genre is showing no signs of loosening its grip on viewers, who have helped propel series into sprawling universes.

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Mar 26 • 6:00 AM EDT • Entertainment • latimes.com
Another co-founder is exiting Elon Musk's xAI

Manuel Kroiss is one of 11 engineers who helped launch xAI alongside Elon Musk in 2023. The number of cofounder departures now sits at 10.

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Mar 25 • 2:44 PM EDT • Business • businessinsider.com
Decoding the Visual World

Learn how NSF's long-standing investments helped computers learn to identify and interpret images, advancing technologies now integral to people's daily lives.

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Mar 25 • 1:43 PM EDT • Science • nsf.gov
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'The Pitt' Star Noah Wyle Talks Universal Health Coverage, Season 3

The hit drama took the London spotlight ahead of the U.K. launch of HBO Max, as Wyle shared how his years of TV doc experience helped when the producer of 'KPop Demon Hunters' needed a medical hand this awards season.

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Mar 24 • 6:44 PM EDT • Health • hollywoodreporter.com
Ron DeSantis says Sean Hannity helped mend 2018 tiff between Donald Trump, top Florida Republicans over Hurricane Maria

It could have gone very differently had the conservative media icon not persuaded the President to drop a grudge.

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Mar 24 • 6:15 PM EDT • Politics • floridapolitics.com
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Rural health care providers can now apply for $50M to stabilize access -  New round of health care funding builds on record $146M investment  - Office of the Governor

SANTA FE – New Mexico’s rural health care providers can now apply for a share of $50 million in health care funding as part of the State of New Mexico’s three-year, $146 million investment that has helped recruit more than 800 health care workers to underserved communities. The funding comes from New Mexico’s Rural Health […]

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Mar 24 • 5:49 PM EDT • Health • governor.state.nm.us
We disagreed on politics. We agreed on wine. That was enough.

At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.

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Mar 23 • 10:54 PM EDT • Politics • dmwineline.substack.com
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Scientists found a rhino in the Arctic and it changes everything

Scientists have uncovered a new species of rhinoceros in the Canadian High Arctic, revealing that rhinos once lived far farther north than expected. The fossil, dating back 23 million years, is unusually complete and has helped reshape ideas about how these animals migrated between continents. Evidence suggests rhinos crossed from Europe to North America more recently than scientists once thought.

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Mar 23 • 8:00 PM EDT • Science • sciencedaily.com
From One Major to Three in Four Years: Connecting Data Science, German and Linguistics at Montclair

In a German language program for local children and on an archive translation project, Isabella Zarate Gonzalez shows how Montclair’s mix of STEM, world languages and community engagement helped her connect her interests into a single path

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Mar 23 • 8:00 PM EDT • Science • montclair.edu
Trump Poised to Skip CPAC For First Time in a Decade

President Donald Trump is poised to skip the Conservative Political Action Conference this week, breaking with an annual tradition that has helped define his political rise and shaped the conservative movement.

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Mar 23 • 11:52 AM EDT • Politics • time.com
David Gallo opens up about why AI data centers, private equity are good for his company

After Katrina, David Gallo led his family's company, Gallo Mechanical, through a geographic expansion that helped grow the company to nearly $500 million in revenues and more than 700 employees. Last year, he led the 80-year-old business through a sale to a private equity firm. In this week's Talking Business, he explains why it was a good thing

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Mar 23 • 5:00 AM EDT • Business • nola.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
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Mar 21 • 10:40 PM EDT • Sports • theadvocate.com
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Pappas Statement on Passage of Legislation to Fund Critical Small Business R&D Programs

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Mar 17 • 4:55 PM EDT • Business • pappas.house.gov
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Mar 16 • 7:10 AM EDT • Sports • sports.yahoo.com
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