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US trade deficit widens in August amid strong imports
The US trade deficit rose to $105.6 billion in August due to a surge in imports, reflecting strong domestic demand and impacting economic growth.
Bette Davis knew her ‘era’ was ‘over’ when she saw Michael Keaton as Batman
Legendary Hollywood star Bette Davis died just days after she saw a giant poster of Michael Keaton as Batman: ‘I’ve come here to pass the torch.’
Into the Slaughterverse: How ‘Something Is Killing the Children’ cut into film, TV, and books
Into the Slaughterverse! ‘Something Is Killing the Children’ creator James Tynion IV talks expanding his comics into a horror universe with a film, animated TV show, and prequel novel.
NASA’s Webb Captures Commotion From Nebula’s Stellar Jets
A cauldron of cosmic creation is being revealed in a new image from NASA’s James Webb Space Telescope. Webb has unveiled numerous stars formerly hidden by
How West Michigan’s power players earned their first paychecks
Before they led companies and institutions, the Who's Who washed dishes, delivered newspapers, picked blueberries and flipped burgers.
Catalytic confessions and a quest for Matt Damon: PodCAT puts science on mic
PodCAT, hosted by researchers from Rice, the University of Rochester and Penn State University, is a podcast devoted to the science of catalysis, academic careers and the surprisingly personal stories of the researchers themselves.
Goodbye joint replacements? Stanford scientists found a way to regrow cartilage and stop arthritis
Scientists have found a surprising way to regrow damaged knee cartilage by blocking a protein that becomes more abundant with age. In old mice, the treatment restored naturally lost cartilage and also helped prevent osteoarthritis after ACL-like knee injuries, while human cartilage taken from knee replacement patients began producing new, functional joint cartilage after exposure to the same inhibitor.
New Study in Health Affairs Documents Rapid Rise in Healthcare Spending in Massachusetts After COVID-19 Pandemic
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GTA 5 Made Playable in Browser as AI-Generated Game Chaos Continues
Grand Theft Auto 5 was made playable in a browser before it was pulled offline, amid an explosion of AI-fueled games across the internet.
UCSF Health Reaches 25,000 Robotic Surgeries
Surgeons at the UC San Francisco have performed over 25,000 robotically assisted minimally invasive surgeries, making it the first University of California health center to reach this milestone. UCSF Health has the busiest robotic surgery program in the UC Health system and is one of the leading academic medical institutions for robotic surgeries in the Western U.S.
Groundbreaking Ceremony Celebrates Aberdeen's Public Works Building, New Business Park
Past and present city officials gathered with numerous public works employees and state and local economic development officials to celebrate the start of
Banijay Entertainment Introduces New US Gameshow Scrambled Up to Market
Media and entertainment powerhouse, Banijay Entertainment, today announces it has acquired the global format rights and finished tape rights to Scrambled Up, an all-new studio-based word game from Michael Eisner’s The Tornante Company; Keller/Noll, the prolific US format creators Cleve Keller and Dave Noll (Chopped, America Says, Flip Side); Crazy Legs Productions; and Playing Field […]
Xbox Elite Series 3 Controller Leaked Via Microsoft's Own Design Lab
Is an announcement imminent?
Nobel Prize in physics awarded to Francis Halzen for his work detecting cosmic particles
The 2026 Nobel Prize in physics has been awarded to Francis Halzen for his “decisive contributions to the IceCube Neutrino Observatory and the discovery of high-energy neutrinos of astrophysical origin.”
Dave McCormick dreams of strengthening science, but Trump is researchers’ worst nightmare
The Pennsylvania senator’s gentle advocacy for NIH funding has had little apparent impact on the president he wholeheartedly supports.
Minnesota gubernatorial candidates discuss business platforms at Economic Club discussion
Minnesota gubernatorial candidates Sen. Amy Klobuchar (DFL) and Rep. Lisa Demuth (R) faced off Monday afternoon in a forum hosted by the Economic Club of Minnesota. Each candidate took the stage independently to answer questions from a moderator for 30 minutes apiece.
Minnesota gubernatorial candidates discuss business platforms at Economic Club discussion
Minnesota gubernatorial candidates Sen. Amy Klobuchar (DFL) and Rep. Lisa Demuth (R) faced off Monday afternoon in a forum hosted by the Economic Club of Minnesota. Each candidate took the stage independently to answer questions from a moderator for 30 minutes apiece.
Zinedine Zidane hails ‘exceptional’ Michael Olise
France head coach Zinedine Zidane has described Bayern Munich’s Michael Olise as “exceptional” after his team’s 4-1 win over Belgium on Monday. Les Bleus came from behind to score four late go...
Poll: Cost of Health Care and Gas Top Voters' Midterm Concerns; Democrats Hold Significant Advantage on Health Care Costs and Cost of Living
Just a month away from the midterm elections, affordability worries continue to top the public’s list of midterm election issues, with health care costs and gas costs tying as the top economic concern, KFF’s new Health Tracking Poll finds. Voters overall trust Democrats more than Republicans to handle the cost of health care and the cost of living.
Nobel Prize in Physics to Be Awarded in Stockholm
STOCKHOLM (AP) — The Nobel Prize in physics will be announced Tuesday by the Royal Swedish Academy of Sciences in Stockholm. Last year, three scientists won the Nobel Prize in physics for research on the strange behavior of subatomic particles called quantum tunneling that enabled the ...
ClickFix Smuggles Payloads Through Browser Cache to Bypass Windows Run Limits
Microsoft observed ClickFix attacks using browser cache smuggling to execute cached VBScript and launch a credential-targeting malware chain.
The Business Behind the Blooms
Natalie Noll ’26 is putting her economics degree to work as the founder of Nova Flora, using lessons in pricing, markets and operations to build her floral business.
Northern Essex’s McCarthy Joins New Small Business Advisory Council
Michael McCarthy, executive vice president and chief financial and operating officer at Northern Essex Community College, was recently appointed to the Massachusetts Small Business Development Center statewide Advisory Council, a new group of business, government, economic development and community leaders helping guide the future of small business support in the state. The Advisory Council was
UK retail conglomerate acquires minority stake in Under Armour
A U.K. retail conglomerate founded by British billionaire Michael Ashley has become a significant investor in Baltimore-based Under Armour. Frasers Group, the parent company of Sports Direct stores and other
Vance says Alaska project will proceed after Trump warns Korea
Vice President JD Vance said an Alaska natural gas project with South Korea will move forward even as Seoul said its participation remains conditional on the venture being economically viable.
Apple Announces iPhone Duo Apps Can Now Be Submitted to App Store
Apple today announced that apps optimized for the iPhone Duo can now be submitted for App Store approval, ahead of the foldable device launching on Friday, October 23. While existing App Store apps will automatically run on the iPhone Duo, only apps built with the iOS 27.1 SDK or later can dynamically resize to fill the entire space of the inner display, whereas unoptimized apps will have black borders.
Former Michigan DE suffers season-ending injury with Jets
According to a report from ESPN’s Adam Schefter, McGregor suffered a torn pectoral muscle during Sunday’s loss to the Chicago Bears.
Curiosity Blog, Sols 5029-5035: Back in the Lab
Written by Michelle Minitti, MAHLI Deputy Principal Investigator
Scientists finally see how nature moves energy so efficiently
Researchers have captured key steps in a chemical reaction that helps nature transfer energy with remarkable efficiency. Ultrafast X-rays revealed how changes involving electrons and protons are closely linked to the rearrangement of surrounding water molecules. Because similar reactions drive photosynthesis and other energy-conversion processes, the technique could help scientists develop better catalysts, fuel cells, and flow batteries.
Canonsburg reviews business growth in workshop
Canonsburg officials and business leaders met last week to review the past six years of economic growth and plan for the future. The borough has seen a marked upswing in downtown business growth in recent years thanks to targeted redevelopment efforts, local business associations and a focus on diverse local events to drive customer traffic. […]
'Tacoma isn’t safe’: Downtown businesses call for action after double homicide
Tacoma police are investigating after two men were shot and killed downtown just before 12:30 a.m. Sunday.
Hadley man had an online business selling radioactive chemicals
Jacob D. Miller had an online business called "Collect the Periodic Table" that he ran out of his home in South Hadley, federal prosecutors said.
Irene Butter: Public Health Scholar, Holocaust survivor, dies
Beginning in 1966, Butter taught at the University of Michigan, focusing on health care, midwifery, and women's health. She became Professor Emeritus of Public Health in 1996.
Dysfunction rocks county health dept. at center of Michigan MAHA movement
Nurses allege a toxic workplace has taken root at the St. Clair County Health Department. But officials are shrugging off calls for an independent investigation of its anti-vaccine medical director.
Jeremy Fears Jr. Voted Big Ten’s Preseason Best
Michigan landed two guards on the preseason All-Big Ten team, and Jeremy Fears Jr. had the last word. #GoGreen
Orlando Science Center returns with themed laser shows on Oct. 10
Orlando Science Center returns with Cosmic Concerts on Oct. 10, featuring laser tributes to Led Zeppelin and Elton John.
Tony Gilroy on Leaving the Politics of 'Andor' Behind for His 9-Composer Music Drama 'Behemoth!'
NEW YORK (AP) — Long before Tony Gilroy wrote “The Bourne Identity," made “Michael Clayton” or created “Andor,” he wanted to be a musician. After playing guitar in a string of bands, Gilroy came to Los Angeles hoping to become a studio musician. A session with some real players quickly disabused him ...
CMS student among top 30 finalists nationwide in science competition
Isabella Garry is being honored for a project exploring whether natural materials can remove microplastics from simulated stomach fluid.
El-Sayed explains what he means by getting the money out of politics
Michigan Democratic Senate nominee Abdul El-Sayed details his Medicare for All plan while advocating for politicians to not take money from big corporations on ‘The Story.
KBOCC, NMU sign articulation agreement for business degree program
The Keweenaw Bay Ojibwa Community College and Northern Michigan University have come to a new articulation agreement to allow KBOCC students to continue their business education at NMU.
Nasdaq notches record high close as investors focus on earnings
Nasdaq reached a record high close driven by Nvidia and Microsoft gains amid investor focus on earnings and lower oil prices.
McAllen’s Soft-Landing Program Generates Business Interest in Tampico, Mexico
The City of McAllen is expanding its economic diplomacy efforts following a successful business engagement in Tampico, Tamaulipas, Mexico, where approximately 25 prospective business owners expressed interest in expanding into the United States through McAllen’s Soft-Landing Program.
Chip City closes all locations amid economic challenges
Chip City, a New York City-based gourmet cookie chain, has closed all 22 remaining locations nationwide due to tough consumer spending and evolving preferences.
Yes on Prop 2: How We Can Get Money Out of Michigan Politics!
This November, Michiganders can vote yes on Prop 2 and get corporate spending — including by the data center industry — out of our politics.
Dead star likely birthed a new planet, in astronomical first
A white dwarf probably created a rare ‘second-generation’ planet.
Wall Street Journal Puts Michigan’s Collapse on National Stage
The Wall Street Journal says Michigan is wobbling after the Minnesota loss dropped the Wolverines to 3-2. #GoBlue
Iowa Legislature expands MEGA program, creating path for steel plant incentive
During a special session on Friday, the Iowa Legislature expanded the Major Economic Growth Attraction (MEGA) program, paving the way for a tax incentive for Mesabi Metallics to construct a steel plant in Lee County. Gov. Kim Reynolds signed the bill into law on Friday. The MEGA program, administered through the Iowa Economic Development Authority,…
Now Open! APSA Teaching & Learning Conference Awards and Travel Grants | Deadline: November 16, 2026 -
Now Open! Apply for TLC Travel Grants & Awards Michael Brintnall Teaching and Learning Award APSA Award for Teaching Innovation | Travel Grants Deadline: November 16, 2026, 11:59PM ET Join political science teacher-scholars and students [...]
Now Open! APSA Teaching & Learning Conference Awards and Travel Grants | Deadline: November 16, 2026 -
Now Open! Apply for TLC Travel Grants & Awards Michael Brintnall Teaching and Learning Award APSA Award for Teaching Innovation | Travel Grants Deadline: November 16, 2026, 11:59PM ET Join political science teacher-scholars and students [...]
Sports Commission seeks to bring world's 3rd-largest sporting event to St. Louis: Rugby World Cup
The St. Louis Sports Commission has submitted a formal bid for the region to host matches during the 2031 Men’s Rugby World Cup, a move that could bring one of the world’s largest sporting events and its associated economic impact to the area.
Michael Douglas recalls shocking response from friends after cancer diagnosis
Michael Douglas says his cancer diagnosis revealed how few people in his life would check in.
Top Iranian official admits dire state of the economy: Report
A top Iranian official reportedly admitted that Iran’s economy is in dire straits due to the war and the U.S. blockade of the country. Mohsen Rezaei, secretary of the Supreme National Security Council and former commander in chief of the Islamic Revolutionary Guard Corps, made the admission Saturday at a high-level government meeting focused on […]
Michael Douglas recalls painful response from friends after cancer diagnosis
Michael Douglas says his cancer diagnosis revealed how few people in his life would check in.
RWJBarnabas Health President and CEO Mark E. Manigan Named 2026 NJBIZ Executive Excellence Honoree
Mark E. Manigan, President and Chief Executive Officer of RWJBarnabas Health, the largest, most comprehensive academic health system in New Jersey, has been named a 2026 Executive Excellence honoree by NJBIZ, recognizing his leadership and impact on New Jersey’s health care landscape. Mr. Manigan and the other honorees will be recognized by NJBIZ at an awards ceremony taking place today.
Supreme Court rejects Michigan woman's appeal over school's ban on 'Let's Go Brandon' sweatshirts
The mother of two boys says their First Amendment rights were violated when they were told to take off the sweatshirts she bought them for Christmas in 2022.
Largest gift in Franklin College history to pay for new business and pre-law building
The college plans to build a two-story academic facility featuring a mock courtroom for pre-law students and an investment trading lab aimed at business majors.
‘The Voice’ Fans, Michael Bublé Teased His Latest TV Project on Instagram
He’s bringing a Property Brother with him.
RWJBarnabas Health President and CEO Mark E. Manigan Named 2026 NJBIZ Executive Excellence Honoree
Mark E. Manigan, President and Chief Executive Officer of RWJBarnabas Health, the largest, most comprehensive academic health system in New Jersey, has been named a 2026 Executive Excellence honoree by NJBIZ, recognizing his leadership and impact on New Jersey’s health care landscape.
Luke Fickell's 'vision' starting to show, Joe Thomas says
After the Wisconsin Badgers dominated Michigan State on Saturday, Hall of Famer Joe Thomas broke down the team's progress.
Michael Duff set to be given the Bradford job
Bradford City are expected to name Michael Duff as the new manager according to reports.The Bantams have been looking for a new boss after Graham Alexander left the club to join Championship side Pre...
Offensive Line Looks Offensive: Spartans Rank Last in Sacks Allowed
From personnel shifts to coaching failures, a crumbling front wall has left the Spartans reeling as record-breaking sack numbers threaten to derail the Pat Fitzgerald era.
Windows 11 26H2 brings a hidden performance boost — and may slash RAM usage
Windows 11 26H2 quietly brings several performance improvements, including a Low Latency Profile that makes common tasks feel faster. Some users are also reporting lower RAM usage after the update, although Microsoft has not confirmed that 26H2 itself is responsible.
How will Florida's minimum wage increase to $15 affect workers and businesses?
A University of South Florida economics professor shares insight on concerns over the recently raised minimum wage in Florida on "The Florida Roundup."
Inspired By My Love Of STEM, I Collaborated With 22 Teens To Write A Kids Picture Book About Science
Teen STEM student Eliana Miao wrote a picture book about the microbiome and empathy titled "The Brave Fuzzy: A Microbiome Story"
Supreme Court rejects appeal over Michigan school's ban on ‘Let’s Go Brandon’ sweatshirts
The Supreme Court is rejecting an appeal from a Michigan woman challenging a school district’s ban on shirts with the phrase “Let’s Go Brandon.” | 830 WCCO
Supreme Court rejects appeal over Michigan school ban on ‘Let’s Go Brandon’ sweatshirts
The Supreme Court is rejecting an appeal from a Michigan woman challenging a school district’s ban on shirts with the phrase “Let’s Go Brandon.” | KNSS Radio
Who will rural voters blame for harmful healthcare changes, policies this election?
Inflation and affordability, immigration and international conflicts may be dominating much of the news—and voters' attention—but healthcare, as always, still matters at the ballot box—perhaps even more so for rural voters.
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | 830 WCCO
Michael Douglas on 'immortality,' Kirk Douglas and the memories he once avoided
Michael Douglas, the award-winning actor and producer, recently turned 82 and has released a memoir titled “One Helluva Ride.” | WWJ Newsradio 950
Eyes on Growth: TD Survey Finds Small Businesses Confident About Growth Despite Economic Headwinds and Delayed Investments
TD Bank U.S. survey finds 85% of small business owners expect stronger revenue through year-end, despite economic uncertainty and preparedness gaps.
Astronomers say they’ve spotted the first miniature quasar pointed at Earth
Microblazars — a miniature version of blazars — may be responsible for mysterious ultra-high-energy particles.
From 4-H Member to Healthcare Leader: A Conversation with Davina Ferrero King
"My 4-H experience helped establish UConn in my mind as a place where I could continue growing academically, professionally, and personally."
You should care about politics
Ever since America’s founding, the United States has been extremely politically charged. From the civil war in the 1860s, to the civil rights movements of the 1950s, America has always had politics at the root of economic, social and institutional change. So then why do Americans care so little about it? In 2024, about 63.9...
Scientists reveal what seven days of fasting does to the human body
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.
The Economics of Delta Healthcare
How well is the system? Experts weigh in on status While agriculture rightfully gains most of the headlines when it comes to the Delta’s economy, the role of healthcare in the region cannot be underestimated. Many challenges face healthcare providers in the region and the state recently stepped in to assist. Nonetheless, healthcare leaders in […]
Duff set to be appointed Bradford boss
Bradford City are set to appoint former Wycombe Wanderers boss Michael Duff as their new manager.
Anthropic AI agent uses human scientists as tools, emails 1,500 without instructions
ColonistOne, built on Claude Opus, autonomously contacted researchers to troubleshoot bugs and seek methods, raising concerns over academic spam and AI autonomy
PFF ranks Michigan State's top five offensive players vs. Wisconsin
Check out who PFF ranked as Michigan State's top five offensive players against Wisconsin.
RBI sees no signs of expropriation of Russian business, CEO says
Raiffeisen Bank International currently sees no signs of an expropriation of its Russian business, CEO Michael Hoellerer said on Monday, after several attempts by the Austrian lender to sell the division have failed.
Integral Ad Science to Provide Brand Safety and Suitability Measurement in ChatGPT Ads
NEW YORK, October 05, 2026--As artificial intelligence rapidly reshapes digital advertising, marketers face a critical new challenge: ensuring brand safety and suitability within dynamic, generative AI-native environments. Without independent verification, advertising in conversational channels risks creating a blind spot for enterprise brands seeking reliable media quality standards.
Top Links 1245 Jobs in health care. Jobs for women. The US labour market is segmenting. Chernobyl’s radiation and Lenin’s love of literature.
Thank you for your support of Chartbook. Your generosity keeps this show on the road. Elmer Bischoff, Two Figures at the Seashore, 1957 The only really dynamic job-creator in the US economy is health care:
Jobs in health care. Jobs for women. The US labour market is segmenting. Chernobyl’s radiation and Lenin’s love of literature.
Thank you for opening your Chartbook email. Elmer Bischoff, Two Figures at the Seashore, 1957 The only really dynamic job-creator in the US economy is health care: The largest crunch has come in Federal government, which has shed 2.7 m jobs. Source: tchouvkov on Twitter Tech is struggling. [ Joey Politano 🏳️🌈@JosephPolitano The US tech sector continues bleeding jobs in official data released today—overall, employment decreased by 17k last month and is down 69k over the last year That's nearly as bad as the worst of the 2024 tech-cession, and much worse than the 2022 boom or even pre-2020 norms 12:42 PM · Oct 2, 2026 · 15.2K Views 15 Replies · 47 Reposts · 390 Likes ](https://x.com/JosephPolitano/status/2106001807847940232?s=20) The new jobs are all for women. [ Justin Wolfers@JustinWolfers I'm not sure who saw this coming, but so far nearly all the jobs created during the second Trump administration have gone to women. 1:09 PM · Oct 2, 2026 · 33K Views 70 Replies · 146 Reposts · 644 Likes ](https://x.com/JustinWolfers/status/2106008723533533601?s=20) Meanwhile, real wages are being eaten up by modest over-target inflation. [ Heather Long@byHeatherLong The financial pain is real: Wage growth fell to 3% (y/y) in September. That's the lowest in 5 years. Wage growth: 3% Inflation: ~3.4% Inflation has eaten up all wage gains for the average worker since April. Many people are having to make hard choices about what to buy and what … 1:24 PM · Oct 2, 2026 · 37K Views 24 Replies · 275 Reposts · 533 Likes ](https://x.com/byHeatherLong/status/2106012367712620728?s=20) HEY READERS, THANK YOU for opening the Chartbook email. I hope it brightens your day. I enjoy putting out the newsletter, but tbh, what keeps this flow going is the generosity of those readers who clicked the subscription button. If you are persuaded to click, please consider the annual subscription of $60. It is both better value for you and a much better deal for me, as it involves only one credit card charge. Why feed the payments companies if we don’t have to. Subscribe Elmer Bischoff, Bathers, 1960 Americans are disillusioned with higher ed. For contributing subscribers only. Subscribe Where the Chernobyl radiation went. h/t Simon Kuestenmacher aka simongerman600 How Lenin’s love of literature shaped the Russian Revolution - Tariq Ali This, then, was the intellectual atmosphere in which Lenin came of age. His father, a highly cultured conservative, was the chief inspector of schools in his region and much respected as an educationalist. At home, Shakespeare, Goethe and Pushkin, among others, were read aloud on Sunday afternoons. It was impossible for the Ulyanov family – “Lenin” was a pseudonym adopted to outwit the tsarist secret police – to escape high culture. At high school, Lenin fell in love with Latin. His headteacher had high hopes that he might become a philologist and Latin scholar. History willed otherwise, but Lenin’s passion for Latin, and taste for the classics, never left him. He read Virgil, Ovid, Horace and Juvenal in the original, as well as Roman senatorial orations. He devoured Goethe during his two decades in exile, reading and rereading Faust many times. Lenin put his knowledge of the classics to good use in the time leading up to the October revolution of 1917. In April of that year, he broke with Russian social-democratic orthodoxy and, in a set of radical theses, called for a socialist revolution in Russia. A number of his own close comrades denounced him. In a sharp riposte, Lenin quoted Mephistopheles from Goethe’s masterwork: “Theory, my friend, is grey, but green is the eternal tree of life.” Source: The Guardian Elmer Bischoff, The River, 1953 If you’ve scrolled this far, you know you want to click: Subscribe
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
UT San Antonio Health Science Center study finds elevated levels of toxicants in teeth of children with autism
Suggests children are ‘chronically and repeatedly exposed’ to dozens of potentially harmful chemicals Contact for media: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Claire Kowalick SAN ANTONIO, Oct. 5, 2026 – A pilot study by The University of Texas at San Antonio Health Science Center found elevated levels of toxicants in the primary teeth […]
UT San Antonio Health Science Center study finds elevated levels of toxicants in teeth of children with autism
Suggests children are ‘chronically and repeatedly exposed’ to dozens of potentially harmful chemicals Contact for media: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Claire Kowalick SAN ANTONIO, Oct. 5, 2026 – A pilot study by The University of Texas at San Antonio Health Science Center found elevated levels of toxicants in the primary teeth […]
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