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Bon Secours Mercy Health affiliate will buy Surgery Partners for about $5.7 billion
Surgery Partners shareholders other than Bain Capital would receive $23.50 a share in cash; the deal is expected to close in early 2027
First 2 billion years of universe's existence revealed in mind-blowing simulation: 'Exciting new frontier'
They're bringing the Big Bang Theory to life.
Anthropic's IPO Filing Shows Staggering Revenue Growth, Huge Losses
Anthropic IPO S-1 is published, a major step toward a public offering that could value the company at $2 trillion.
As Trump brags about U.S. oil and gas company profits, his stocks gained millions during Iran war
A report from congressional Democrats found the president purchased millions in oil and gas stocks during the war.
Meta Plans To Raise Up To $95 Billion In Equity To Power AI
Meta stock was lower premarket after the tech giant announced plans to raise $95 billion in equity.
Anthropic releases IPO filing ahead of highly-anticipated stock debut
The offering could value the Claude AI developer at more than $2 trillion.
Fanatics teams up with OpenAI for new AI-powered shopping suggestion feature
Fanatics is using AI to help shoppers navigate more than 1.5 million items of sports merchandise, with a Shop the Look feature powered by OpenAI Codex.
OU receives more than $5M for maternal health research
OU’s College of Nursing secured more than $5 million in new NIH funding for four maternal health research projects over four years.
Suki Secures $90 Million | Confido Health Expands Agentic Operating Platform
Check out today's featured companies who have recently raised a round of funding, and be sure to check out the full list of past healthcare IT fundings.
Georgia’s Audi megadeal comes with political flashbacks
With Election Day nearing, President Donald Trump unveiled plans for a $4.2 billion Audi plant in Middle Georgia, reviving a familiar GOP election-year playbook.
In brief: Orlando Bloom, Elijah Wood joining 'The Gentlemen'
Netflix is rounding up more gentlemen. Tudum announced Orlando Bloom, Elijah Wood and Ed Speelers are joining stars Theo James and Kaya Scodelario for the third season of The Gentlemen, which is currently filming in the U.K. and Morocco. Also added to the series cast are Dexter Fletcher, Robert Carlyle and Bugzy Malone, who appeared in the 2019 film that inspired the Netflix series. Daniel Ings, who played the drug-addled older brother Lord Frederick “Freddy” Horniman to James’ criminal mastermind Eddie Horiman, told HATC magazine he will not return for the third season. Netflix has not confirmed this …The action-adventure series Fallout has inspired a new reality show. Prime Video has revealed Fallout Shelter: The Experiment, an unscripted competition inspired by the post-apocalyptic drama series and the video game universe. The show “invites everyday participants to test their aptitude for the apocalypse in Vault-Tec's state-of-the-art bomb-proof vault shelters," according to Prime Video. Contestants will “go head to head in a series of high-octane drills, psychological dilemmas and morally challenging behavior trials.” The winner walks away with a $1 million prize. Fallout Shelter: The Experiment will begin streaming in January 2027 … TNCMS.AdManager.render({region: 'fixed-big-ad-top-asset', slot: 1, fold: "above"}); Bravo renewed a slate of its reality shows ahead of Bravo’s Fan Fest on Saturday. New York-based In the City has been greenlit for season 2, while Next Gen NYC is coming back for a third season. For viewers seeking a little Southern charm, The Next Gen universe will be expanding with a spinoff based in Atlanta, and Southern Hospitality is moving forward with a fifth season. Premiere dates have not yet been announced … Copyright © 2026, ABC Audio. All rights reserved. Thank you for reading kmaland.comAt KMA, we attempt to be accurate in our reporting. If you see a typo or mistake in a story, please contact us by emailing kmaradio@kmaland.com.
The State of Politics: How The Tax Break for Data Centers Was Passed
$1.9 billion annual handout to massive tech companies quietly put into 2023-25 budget.
Financial Woes Looms Over Washington's Revenue Sports
With Washington basketball's season set to tip off in just a few days, the second of the Huskies' two revenue sports finds itself in a very similar predicament to the football team. According to a recent report from CBS surveying the roster spending of college basketball programs across the nation, Danny Sprinkle's program ranked last in the Big Ten, spending approximately $5-7 million in NIL on its players.
2.9K views · 17 reactions | Over $10 billion has been spent so far on...
Over $10 billion has been spent so far on ads for the midterm elections, according to media tracking firm AdImpact. But who is paying for those ads? We dug into the data. https://wapo.st/4zKTGk7
Southern Utah is turning away millions in convention business. Washington County has a $30M idea to change that.
Washington County says it's turning away millions in convention business. Its solution? A $30 million expansion of the Dixie Center.
Data center boom brings premium growth, risks
Billions of dollars in data center construction are generating significant insurance demand, but a growing challenge for insurers is the accumulation of exposures rather than a broad shortage of…
Meta looks to raise up to $95 billion from stock sales for AI build out
Meta is seeking more cash as it spends heavily on AI infrastructure, data centers, and computing power as it develops consumer AI products.
Lions vs. Vikings odds: Opening lines for Week 8 matchup
Checking in on the opening betting odds for the Week 8 matchup between the Detroit Lions and the Minnesota Vikings.
Golden celebration: Riverview Health Foundation commemorates 50th anniversary
What began in 1976 as a community effort to raise funds for equipment and hospital needs has evolved into a foundation that is set to have raised more than $19 million for local healthcare by the end of this year. The Riverview Health Foundation commemorated its 50th anniversary during an Oct. 2
The Political Calculus Behind Newsom’s Opposition to California’s Billionaire Tax
Proposition 40 proponents say the tax would help backfill federal Medical cuts. But as Newsom weighs a presidential run, is he also looking ahead to how it might play to donors and voters?
NFC playoff picture: Lions win to jump Packers
The Detroit Lions moved up in the NFC playoff picture after their win over the Packers.
Potential buyer of Weiss and West Suburban hospitals has mixed track record
Insight Chicago owes tens of millions of dollars to the state, and its Bronzeville hospital has been cited for numerous safety issues.
Exclusive: Health tech PE megadeals surge as deal volume drops
The average health care buyout size jumped to $3.4 billion in the first half of 2026.
Ex-OpenAI Science Chief Kevin Weil Raises $215M for Drug AI
Former OpenAI science head Kevin Weil launches Warp Sciences with $215 million to use AI and robotics for a critical stage of drug development.
Is Lions coach Dan Campbell taking too many risks?
The Detroit Lions are winning football games, but should Dan Campbell tone down the gambling?
Trump’s D.C. hotel is gone. Mar-a-Lago is now a GOP campaign cash magnet.
Republican campaigns, party committees and PACs have spent nearly $3 million at Trump businesses since his return to office, a Post analysis finds.
Inside the Trump Administration's Dismantling of a Health Care Research Office
The Agency for Healthcare Research and Quality has few remaining grant officers and has redirected millions in taxpayer dollars without telling Congress.
Student-loan borrowers' key midterms issue: affording higher bills
Over 10 million student-loan borrowers are behind on payments. Some are hoping the midterms will prompt policy change to protect those in default.
Micro1 invests $1B to license data for AI model development
Micro1 is pledging $1 billion to gobble up more companies' internal data for licensing to AI model developers, part of a new wave for the tech.
Republicans are spending millions and still may not win districts drawn to favor them
Republicans redrew Congressional district lines to try to tilt the midterms in their favor. But now they are facing expensive and competitive races they had hoped to outmaneuver.
Republicans are spending millions and still may not win districts drawn to favor them
Republicans redrew Congressional district lines to try to tilt the midterms in their favor. But now they are facing expensive and competitive races they had hoped to outmaneuver.
Smithsonian scientists launch "Lumina" simulation to model early universe
Researchers introduce "Lumina," a massive cosmological radiation-hydrodynamics simulation designed to model the universe's first two billion years
Hollywood's uncanny evolution of evil billionaire tech bros
If you really want to understand the extent to which everyone thinks Silicon Valley is so uncanny these days, watch "Cupertino."
Concordia University - 50 Years In
Concordia University Irvine marks 50 years: from 36 students in 1976 to 28,000+ alumni and $45 million in new, debt-free facilities. Explore the milestones.
Raye's three songs enter Spotify's Billions Club
Raye's songs 'Where Is My Husband!,' 'Prada,' and 'Escapism' reached one billion streams on Spotify.
Inglewood Starts Transit Development
Last week, Inglewood city officials broke ground on their scaled-down $261 million Inglewood Transit Connector project aimed at improving mobility between
Goldwind Science & Technology: 9M26 profit reached RMB2.9 billion as WTG sales rose and backlog hit 57.0 GW
9M26 revenue was RMB52.0 billion and attributable net profit RMB2.9 billion. WTG sales rose 3.02% YoY, while total backlog reached 57.0 GW; operating cash flow was negative RMB30 million.Original document: Goldwind Science & Technology Co. Ltd. Class A [002202] Slides Release — Oct. 26 2026This is…
SpaceX secures $40B in financing for GPUs as Elon Musk warns of AI cloud industry consolidation
SpaceX closed $40 billion in debt financing for GPU purchases as Elon Musk warns AI debt markets have shut off access for most companies.
How to Manage Symptoms of Heart Failure
(Feature Impact) Americans are facing a growing health challenge, with 1 in 4 adults at risk of heart failure, according to the Heart Failure Society of America. Additionally, approximately 6.7 million U.S. adults who are 20 years old or older are currently living with heart failure, and that number is projected to reach 8.7 million by 2030. googletag.cmd.push(function() { googletag.display('JGFI_Article_300x250'); }); Managing heart failure is a significant expense to the U.S. healthcare system, costing the nation approximately $40 billion in 2020 and expected to increase to approximately $142 billion a year by 2050.If you (or a loved one) are living with the condition, consider these tips to help manage it.Adhere to the Treatment and Follow-Up PlanOngoing outpatient care is important when managing heart failure. Understand the treatment plan provided by your healthcare team, make diet and lifestyle changes, take medications as directed and keep recommended follow-up appointments.Pay attention to changes in symptoms and communicate with your healthcare provider if treatment does not seem to be working as expected. If their conditions are left unmanaged, patients can experience a range of heart-failure-related symptoms such as shortness of breath, fatigue, buildup of fluid and more.Understand Challenges with Diuretic TreatmentDiuretics help the body remove excess fluid and are commonly used to treat swelling, or edema, associated with heart failure. Your provider may try different diuretics, sometimes referred to as “water pills,” to manage your heart failure symptoms. However, intravenous (IV) diuretic therapy may be required for some patients if symptoms continue.Ask About Treatment Options Before IV Care Is NeededFor some adults, a healthcare provider may consider recommending an at-home, non-oral diuretic option prior to escalating to IV therapy.For example, ENBUMYST™ (bumetanide nasal spray) is a prescription diuretic used in adults to treat edema associated with congestive heart failure. It’s administered as a nasal spray for short-term use to manage excess fluid with the goal of transitioning to oral diuretic therapy when appropriate.Talk with your healthcare provider to learn more and visit enbumyst.com. Read the full Prescribing Information and Patient Information.Photo courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('JGFI_Article2_300x250'); }); Important Safety InformationWhat is ENBUMYST?ENBUMYST is a prescription medicine used in adults to treat swelling caused by excess fluid in the body (edema) from congestive heart failure, liver disease, and kidney disease.What is the most important information I should know about ENBUMYST?ENBUMYST is a diuretic that helps your body remove fluid. Losing too much fluid can cause dehydration, low blood volume, and increase the risk of blood clots. Blood abnormalities may include decreased salts (electrolytes), and increased nitrogen, glucose and uric acid. The risk of these abnormalities is higher in elderly people, those using higher doses, or those who do not get enough electrolytes by mouth.You should not use ENBUMYST if you have severe electrolyte loss. Tell your healthcare provider if you experience unusual thirst; dizziness or lightheadedness; weakness or tiredness; fast heart rate; dry mouth or tongue; sudden pain; redness or swelling in your joints; pain, swelling, redness, or warmth in your leg; shortness of breath or fast breathing; high blood sugar; dark urine; pale, tight, cool or clammy skin; muscle cramps; confusion.Do not use ENBUMYST if you have low or no urine production or are allergic to bumetanide or to any of the ingredients in ENBUMYST.Before using ENBUMYST, tell your healthcare provider if you have low electrolytes, are on a low-salt diet, have diarrhea, diabetes, nasal problems such as a runny or stuffy nose or polyps, a history of nasal injury or surgery, are or plan to become pregnant, are or plan to breastfeed.Tell your healthcare provider about all the medicines you take, including prescriptions, over-the-counter medicines, vitamins, and herbal supplements.ENBUMYST may cause serious side effects, such as worsening kidney function and ringing in the ears or hearing loss.The most common side effects of ENBUMYST include dehydration, headache, muscle cramps, dizziness, low blood pressure, nausea, and abnormal brain functioning with certain liver problems.These are not all the possible side effects of ENBUMYST. Talk to your healthcare provider for more information.Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.US-ENBU-2600110 googletag.cmd.push(function() { googletag.display('JGFI_Article3_300x250'); });
Earnings to watch: Caesars Entertainment (CZR) reports Q3 results tomorrow
Hotel and casino entertainment company Caesars Entertainment NASDAQ:CZRwill be reporting earnings this Tuesday after market close. Here’s what to expect.Caesars Entertainment beat analysts’ revenue expectations last quarter, reporting revenues of $2.99 billion, up 3% year on year. It was a softer q…
Lula is declared winner of Brazil's election as Bolsonaro rejects results
Flavio Bolsonaro is refusing to concede defeat to incumbent President Luiz Inácio Lula da Silva, who bested him by nearly 4.4 million votes, following a chaotic delay in poll closing
Jared Goff goes over 300 yards in Week 7 vs. Packers
Detroit Lions quarterback Jared Goff completed 22 of 32 passes for 303 yards, two touchdowns and no interceptions in Week 7
Scientists Reversed 60 Years of Cellular Aging. Can It Work in Humans?
Scientists reversed 60 years of cellular aging in a lab. As billionaires pour money into longevity research, could humans be next?
Ennis Rakestraw Jr. unable to return after ankle injury
Detroit Lions cornerback Ennis Rakestraw Jr. left the Week 7 game due to an ankle injury, and he was unable to return.
Tucker Kraft scores TD in Week 7 vs. Lions
Green Bay Packers tight end Tucker Kraft finished with four receptions for 48 yards and a touchdown on six targets in Week 7
Lions QB Jared Goff Ties NFL History Against Rival Packers
The Detroit Lions are back in action on Sunday afternoon at Ford Field against the divisional rival Green Bay Packers in a clash that will carry heavy implications for the NFC North standings. And thanks to yet another strong start from quarterback Jared Goff, he’s not only put his club in a position to pick […] The post Lions QB Jared Goff Ties NFL History Against Rival Packers appeared first on HEAVY.
Detroit Lions vs. Minnesota Vikings Point Spread Revealed
The Detroit Lions are 3-point favorites against the undefeated Minnesota Vikings in Week 8. See the latest FanDuel point spread, moneyline, and total.
Supercomputer reveals first two billion years of ‘cosmic web’
The Center for Astrophysics’s simulation offers the most detailed look yet at the infancy of the universe after the Big Bang
6 stellar images of the early universe
The most detailed simulation of our universe’s first 2 billion years to date.
Chinese scientists discover “D-rex,” a giant fungus with roots stretching back 65 million years
Scientists have discovered a giant new fungus in China that grows up to 20 inches tall and weighs nearly five pounds, making it the largest known of its kind. Dubbed “D-rex,” its evolutionary lineage appears to have emerged shortly after the dinosaurs went extinct, raising intriguing questions about how that ancient catastrophe may have shaped its evolution.
Scientists discover Arctic sea ice loss could be far worse than predicted
Arctic winter sea ice could disappear much faster than scientists previously expected, according to new research using climate clues from 6,000 years ago. By comparing ancient ocean sediments with modern climate models, researchers found that future winter ice coverage may be roughly one million square kilometers smaller than earlier predictions suggested.
Lions beat Packers 20-17 on last-play field goal
Packers defensive tackle Devonte Wyatt questionable to return after injury
Green Bay Packers defensive tackle Devonte Wyatt questionable to return after injury vs. Detroit Lions.
Lawmakers propose $11M fix to restore school sports and activities funding
by Katie Klingsporn, WyoFile Wyoming’s new school funding model added more than $250 million in state education funding, including for widely supported
2026's First $1 Billion Movie Finally Confirms Netflix Release Date
Primark's Business Doesn't Make Sense
In a world where fast fashion giants like Shein, Zara, and H&M drop thousands of new styles every day — and rake in billions through e-commerce — Primark is doing the unthinkable: thriving with zero online shopping. So what gives?*Want to Know the 5 Trends Changing Modern Retail? Find Out Here:* 🔗 https://clickhubspot.com/d13ac2In this video, we take you inside Primark’s weirdly brilliant business model — a model that’s stuck in the past on purpose. From warehouse optimization and floor-ready freight shipments to why the pandemic didn’t push them online, we unpack how this low-cost retail giant has managed to defy digital norms… and make it work.This isn’t just about one brand. It’s a story about modern retail expectations — and what it actually takes to meet (or reject) them.Subscribe to The Hustle:🔗 https://clickhubspot.com/vu3lGet the 5-minute newsletter keeping 2M+ innovators in the loop🔗 https://clickhubspot.com/3klnAbout HubSpot: HubSpot is a customer platform that provides education, software, and support to help businesses grow better. The platform includes marketing, sales, service, commerce, operations, and website management products that start free and scale to meet our customers’ needs at any stage of growth. Today, thousands of customers around the world use HubSpot’s powerful and easy-to-use tools and apps to attract, engage, and delight customers.#TheHustle #HubSpot
Rep. Carbajal Meets with Cottage Health’s Head Honchos in Santa Barbara as They Brace for ‘Big Beautiful Bill’ Impacts
Trump’s bill expected to leave close to 40,000 Central Coast residents without health coverage, another 37,000 with higher premiums, and a roughly $40 million initial impact on Cottage.
Editorial: Company mergers are causing more harm to the entertainment industry than good
Two weeks ago, Paramount officially completed its $110 billion purchase of the historic Warner Bros.
Lions Week 7 inactives: EDGE Ahmed Hassanein OUT vs. Packers
Inside 26-year-old’s club for million-dollar Chattanooga business owners
At 2nd American Restaurant on Thursday night, around 85 entrepreneurs who have scaled their businesses to at least $1 million in annual revenue sat to a family-style meal of beef cheek roast, airline chicken and the restaurant's signature bowl of mashed potatoes.
‘You Can See Everything’ surges with $19.5M at box office; ‘Clayface’ takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KCBS All News 106.9FM and 740AM
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KNSS Radio
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday | KMBZ
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday.
'You Can See Everything' surges with $19.5M at box office; 'Clayface' takes No. 1
DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday. But the biggest success story in theaters remained A24’s...
'You Can See Everything' Surges With $19.5M at Box Office; 'Clayface' Takes No. 1
NEW YORK (AP) — DC Studios scored a modest, R-rated win with “Clayface,” landing a $24 million opening weekend, according to studio estimates Sunday. But the biggest success story in theaters remained A24’s Elizabeth Holmes documentary “You Can See Everything,” which pulled in $19.5 million in its ...
Cattle Science Gets a $19.5 Million Upgrade as West Texas A and M Plans High-Tech Research Complex
West Texas A&M is building a $19.5M cattle research complex featuring AI technology, veterinary research and commercial-scale feedlot studies.
Selena Gomez's vaping admission highlights hidden health risks doctors say millions face daily
Selena Gomez called vaping "stupid" after it altered her voice, but doctors warn the health risks go beyond vocal cord damage for millions.
How Braves should handle $42 million Jurickson Profar situation
This could be one solution for the Braves.
Packers Lose Defensive Captain Just Before Massive Showdown With Lions
Green Bay Packers defensive captain Zaire Franklin has been ruled out against the Detroit Lions, leaving Green Bay without both starting linebackers.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Xbox Asked for $800 Million After Netflix Offered $500 Million for Game Adaptation Rights
Netflix offered Xbox $500 million for seven years of exclusive film and TV rights, and Xbox countered with $800 million, Puck's newsletter…
Their friend died of cervical cancer in 2020. Now, they advocate for women’s health in N.S.
Following the death of their close friend from cervical cancer in 2020, two women in Nova Scotia were left wondering how things might have been different had she been diagnosed earlier. Six years later, they have raised over $4 million to improve technology and infrastructure for women's health.
Instacart Stock What Health Benefits Deal And $5 Million Settlement Mean
Instacart parent Maplebear has agreed to a US$5,000,000 settlement with U.S. authorities over past PERM hiring practices and has been selected by True Rx Health Strategists to power an employer funded healthy food benefit through Instacart Health Fresh Funds starting in 2027. The True Rx program positions Instacart within pharmacy benefit design and ties employer spend directly to clinically supervised food choices. The settlement adds compliance obligations, policy changes and monitoring...
Trump touts U.S. oil business making ‘hundreds of billions’
President Trump tells rallygoers in Georgia that the United States’ oil and gas business is making “hundreds of billions of dollars because of what’s happened in the Middle East,” and predicts that prices at the pump will “come way down.”
NFL Week 7 expert picks, score predictions: Packers at Lions
Green Bay Packers vs. Detroit Lions NFL Week 7 expert picks from the Pride of Detroit staff.
DOE expands tribal energy funding to $125M, selects 63 projects
The Department of Energy expanded a $50 million tribal energy funding opportunity to more than $125 million after tribal applications sought roughly 10 times the initial amount. The agency selected 63 tribe-led projects across 16 states for what it described as the largest single investment in the Office of Indian Energy’s history. The projects include […]
Tickets on sale now for 49 Winchester's Charlottesville show next year
49 Winchester, a homegrown Virginia country rock band, is the first band announced for Ting Pavilion's 2027 lineup. Tickets are on sale now.
How LaLiga Turned a Global Soccer Brand Into an $87 Million U.S. Business
LaLiga’s successful expansion into North America shows how to turn a global sports brand into a sustainable business.
Detroit Lions updated depth chart: Week 7 vs. Packers
An updated look at the 2026 Detroit Lions’ depth chart ahead of their Week 7 game vs. the Green Bay Packers.
NVIDIA's open-source path tracer gets 20% faster with RTXPT 1.9
NVIDIA's open-source path tracer now supports up to 2 million lights, SHaRC caching by default and Windows ARM64, alongside multiple rendering optimizations.
Three giant black holes discovered in a galaxy from the dawn of time
Astronomers have discovered three actively feeding black holes inside a single galaxy more than 12.5 billion light-years away, revealing a remarkable scene from the universe’s infancy. Two of the black holes are separated by just 620 light-years and are expected to eventually merge, while a third lurks farther away. One weighs an astonishing 80 million suns, and another is growing faster than conventional theories predict.
AP Exclusive: Trump’s border chief defends wall plans in Texas’ Big Bend despite a court setback
The Trump administration's top border official is defending plans to build a wall in Texas' Big Bend region. Customs and Border Protection Commissioner Rodney Scott argues the entire $46 billion
What Californians should know about Prop. 42
The measure could block the billionaire tax — and more.
AP Exclusive: Trump’s border chief defends wall plans in Texas’ Big Bend despite a court setback
The Trump administration's top border official is defending plans to build a wall in Texas' Big Bend region. Customs and Border Protection Commissioner Rodney Scott argues the entire $46 billion
Green Bay Packers vs. Detroit Lions: How to watch the NFL Week 7 game, channel, streaming info and more
How to watch Lions vs. Packers: TV, streaming, radio, more
TV, online streaming, announcer, and kickoff time information for Detroit Lions vs. Green Bay Packers.
Country music’s richest singer has a stunning net worth of more than $1 billion
You might be surprised to learn who has the biggest bank account.
Guest Commentary: How anti-Muslim politics endangers every Floridian
The political caricature of Muslims as a national security threat bears little resemblance to the reality that Floridians are living, working, and raising families in peace with nearly half a million Muslims woven into the fabric of the state.
'Supercharging bras': The story behind Victoria's Secret's $6 billion business turnaround
Victoria's Secret is in the midst of a historic comeback, with sales surging and its stock on track to notch its best-ever year. What gives? https://bit.ly/4BhD84S
Inside Victoria's Secret's $6 billion business turnaround
Victoria's Secret is in the midst of a comeback, with sales surging and its stock on track to notch its best year ever.
Detroit Lions vs. Packers: Where to watch, TV channel, time
The Detroit Lions welcome in the Green Bay Packers for a pivotal Week 7 game. Here's where to watch, including TV channel and kickoff time.
‘Once we lose these, they’re gone forever’: What will become of the dioramas at the Academy of Natural Sciences?
The museum’s closure could endanger the 32 dioramas. Moving them can cost millions.
The boss whose twice-bust business appears to be back despite £3m debts
Andrew Woosnam took millions from his companies before leaving creditors including HMRC out of pocket
He Took Big Risks to Make Billions. He Wants Georgia Voters to Bet on Him.
Rick Jackson’s run for governor as a political nobody was his latest gamble. The campaign has brought scrutiny to the businesses that made him a fortune.
He Took Big Risks to Make Billions. He Wants Georgia Voters to Bet on Him.
Rick Jackson’s run for governor as a political nobody was his latest gamble. The campaign has brought scrutiny to the businesses that made him a fortune.
In Arkansas, Democrats see an opening at the edge of the competitive midterms map
In a sign of the potentially dire midterm political environment, Republicans have spent millions of dollars playing defense in Arkansas, one of the most conservative states in the country.
Business briefs: Harry Reid airport completes $71 million baggage upgrade
In Terminal 1, the work included upgrades to eight baggage carousels, replacement of eight others, new conveyors and new carousel columns with LED screens. In Terminal 3, the project upgraded the computer hardware and software that control the baggage system …