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From iPhone Duo to Mac, Craft shows what a native productivity app can do
It’s been a busy fall for Apple. iOS and macOS 27 arrived in September, iPhone Duo went on sale just...
NYC Health + Hospitals Recognized as a 2026 Wellbeing First Championship, Supporting Healthcare Worker Wellbeing
NYC Health + Hospitals today announced it has been recognized by ALL IN: WellBeing First for Healthcare as a 2026 Wellbeing First Champion. This is the
Man charged with mailing threatening letters with white substance to members of Congress
Matthew Unglesbee, of Illinois, allegedly mailed four letters to members of Congress in envelopes that contained a white granular substance and his name and home address.
Water quality health advisory lifted for Eastern Lake in Walton County
The advisory had previously been issued due to elevated bacterial concentrations in the coastal dune lake.
Denver Health Medical Plan Discloses Vendor Breach Affecting 238K Members
Denver Health Medical Plan has notified more than 238,000 individuals about a vendor-related data incident. Data breaches have also been announced by Denver Health Medical Plan has notified more than 238,000 individuals about a vendor-related data incident. Data breaches have also been announced by Johns Hopkins Bayview Medical Center and BASS Medical Group.
Ghost of Yōtei Studio Hit by Layoffs Following Complete Edition Launch
Despite Ghost of Yotei's resounding success, an eighth of the team has been laid off.
Cherokee Federal company awarded contract to strengthen US Navy fleet readiness
Cherokee Nation Government Solutions, a Cherokee Federal company, has been awarded a $99.3 million, five-and-a-half-year contract through a competitive small business set-aside under the SeaPort-NxG contract vehicle.
ACHI’S Sarah Crawford Named to AcademyHealth Advisory Panel on Oral Health
Sarah Crawford, ACHI’s assistant director of analytics, has been selected by AcademyHealth to serve on its Oral Health Interest Group Advisory Committee.
Lancaster Twp. nursing and rehab center sold for $10.7M
The Hamilton Arms Center nursing and rehabilitation center in Lancaster Township has been sold for $10.7 million to a partnership affiliated with its operating company.
Baptist Health expands Hospital at Home program to South Jacksonville
More than 300 patients have been transferred to their residences for care.
Grand Theft Auto 6 Review Embargo Date Details
One of the most important dates in gaming history has been revealed: We know when the GTA 6 review embargo is.
‘Miami Vice ’85’ set allegedly menaced by man brandishing a butcher knife
‘Miami Vice ‘85’ filming took a menacing turn on Oct. 23, when a man allegedly brandished a knife on the Brooklyn set of the Michael B. Jordan and Austin Butler film. The man has since been arrested and charged.
Mike Tomlin defends Dan Campbell’s controversial fourth-down decision
Facing fourth-and-one from their own 23-yard line with under five minutes left in a tie game, Dan Campbell and the Detroit Lions did what they do best. They stayed aggressive. Unfortunately, star running back Jahmyr Gibbs was bottled up in the backfield, and the Lions turned the ball over on downs, giving their NFC North…
Zelda 40th Anniversary Switch 2 Pro Controller restock tracker: we’re watching these retailers
🎮 Nintendo will release a Zelda 40th anniversary Switch 2 Pro Controller on October 29 💰 It costs $99.99, the same as other limited editions 📅 A restock could occur on launch day at Walmart and Best Buy 🚨 Our Zelda Switch 2 Pro Controller restock tracker @mattswider on X will send out an alert when stock appears Walmart: Zelda Pro Controller Best Buy: Zelda Pro Controller Amazon: Zelda Pro Controller Target: Zelda Pro Controller GameStop: Zelda Pro Controller Nintendo is releasing a special limited edition Nintendo Switch 2 Pro Controller to celebrate the 40th anniversary of The Legend of Zelda series. It releases on October 29, 2026, which is when we expect to see a long-awaited restock of the hard-to-find controller. 🚨 We’re tracking Zelda Switch 2 Pro Controller stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 The Switch 2 Pro Controller features the same striking gold and royal emerald color scheme of the Nintendo Switch 2 The Legend of Zelda 40th anniversary edition, and also includes a fun little easter egg on the back: an 8-Bit Link. 🚨 Want the Zelda 40th Anniversary Switch 2 Pro Controller? Drop your email for restock alerts before it sells out. ⤵️ Subscribe This is the same Nintendo Switch 2 Pro Controller we’re used to, aside from the intricate design, but it means you’ll have to pay more as a result. It costs $99.99 instead of the standard $89.99. However, the Pro Controller is the easiest way to play the best Switch 2 games in TV mode. If you’ve been searching for a Zelda 40th Anniversary Switch 2 Pro Controller restock, here’s everything you need to know. Zelda 40th anniversary Switch 2 Pro Controller should restock at these retailers We’ve seen retailers such as Walmart and Best Buy restock items on release day, even when pre-orders have sold out. It’s likely that the Zelda Switch 2 Pro Controller will be up for grabs on October 29, 2026, when the controller and console launches. Demand will be high, and stock could sell out fast. However, we’ll be keeping a close eye on every major retailer, including Target, Amazon, GameStop, and the Nintendo Store and will alert our followers as soon as stock goes live. Why you can trust our Zelda Switch 2 Pro Controller restock tracker We’ve already helped over 400,000 people buy a PS5 when it was in and out of stock during Covid, and we’ve helped our subscribers continue to secure hard-to-find items. The Shortcut followers were some of the first to secure the Switch 2 when it went on sale, and we’ve also helped countless others snag limited edition consoles like the PS5 30th anniversary edition. The Shortcut and Matt Swider on X offer exclusive Zelda 40th anniversary Switch 2 Pro Controller restock updates with up-to-the-second US store inventory checks at the biggest retailers. You’ll receive an instant notification on X (if set to on) as soon as new stock arrives. Up next: Call of Duty: Modern Warfare 4 review roundup: ‘a strong return to form’ Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
Mid-Columbia Ballet prepares for 50th anniversary of "The Nutcracker"
RICHLAND, WA. — For 50 years, the Mid-Columbia Ballet has brought the holiday classic The Nutcracker to audiences in the Tri-Cities. This year, the organization is celebrating that milestone with 144 dancers, new costumes and months of preparation to bring the beloved production to life. The annual performance is a major undertaking for the dancers, instructors and volunteers who work behind the scenes to make the show possible. Rehearsals span 13 weeks, with dancers practicing four days a week for multiple hours at a time.This year’s production will feature new costumes for the Waltz of the Flowers, including a sequence with as many as 25 dancers on stage at once. The show also brings together performers across generations, including adults who have been part of the production for more than 20 years. For Artistic Director Debra Rogo, the preparation begins long before the curtains open.Rogo has been involved with the Mid-Columbia Ballet for 40 years and says planning for The Nutcracker takes place throughout the year. While organizing a production of this size requires significant time and effort, she says watching young dancers grow and develop a passion for ballet makes it all worthwhile. “It’s why I do this,” Rogo said. “It is overwhelming ina good way. To be able to share into their lives and watch them develop a love of this art form and the hard work … it makes me very proud.”Rogo’s decades of involvement reflect the lasting impact the production has had on the local dance community. For many performers, The Nutcracker is more than a seasonal performance. It is an opportunity to build skills, create relationships and become part of a tradition that continues year after year.While the dancers spend weeks rehearsing their routines, a large team of volunteers works behind the scenes to support the production.More than 100 volunteers are involved this year, helping make the performance possible. Their contributions reflect the range of people who come together to support the arts in the Tri-Cities.Randy Haven, a longtime volunteer, says the sense of community is one of the things that makes the experience so special.“The people that you hear volunteering, it’s incredible,” Haven said. He described seeing people from different backgrounds working together backstage, from employees at Hanford to parents raising large families.Haven says that shared commitment creates a family-like atmosphere among the people involved in the production. For Rebecca and Torrie, the Mid-Columbia Ballet has been part of their lives since childhood. Both began dancing with the organization at age seven and have since returned as teachers, helping introduce the next generation to the art form.Their connection to the ballet has continued into their adult lives, creating an opportunity to share their love of dance with younger performers.Torrie now has three daughters performing in The Nutcracker, giving her the chance to watch them experience a tradition that was also part of her own childhood.Being able to see her daughters participate in the production has made the experience especially meaningful, she said.Although audiences can see productions of The Nutcracker in major cities such as New York and Seattle, those involved with the Mid-Columbia Ballet say the local performance offers something distinctive.The community atmosphere allows audiences to experience the production while supporting local performers and the people who dedicate their time to the arts.Rebecca says experiencing a live performance alongside other people is particularly meaningful in a world where so much time is spent looking at screens.She believes live art gives people an opportunity to connect with one another through a shared experience.The ballet’s production also gives local dancers the chance to perform for their community while continuing a tradition that has been part of the Tri-Cities for five decades. When to see ‘The Nutcracker’ in RichlandThe Mid-Columbia Ballet will present its 50th-anniversary production of The Nutcracker Dec. 10 through Dec. 13 in Richland.Tickets go on sale Nov. 1. Audiences can look forward to seeing 144 dancers, new costumes and the work of more than 100 volunteers come together for the holiday production.COPYRIGHT 2026 BY APPLE VALLEY NEWS NOW. ALL RIGHTS RESERVED. THIS MATERIAL MAY NOT BE PUBLISHED, BROADCAST, REWRITTEN OR REDISTRIBUTED.
Here are 16 businesses listed for sale in Arlington as of October 2026
A longtime Italian restaurant, a rolled ice cream shop and a family-owned auto repair shop are among more than a dozen local businesses that have been recently listed for sale in Arlington. The businesses appeared for sale as blind items on the online marketplace BizBuySell. Here's a look at some notable listings that are active
Muppets revive “Muppet Christmas Carol” with new A-list actor as Scrooge: ‘Bah humbug!’
Fan-favorite star of “The White Lotus” steps into the role of Scrooge in a new ad.
Owners of Elvis Presley’s music sue Anthropic over un-permissioned AI use
The owners of Elvis Presley’s music are suing Anthropic for using the rock icon’s songs without permission to train AI models. Much has been made of the theft component inherent
📈 Monday data: The bottleneck isn’t intelligence
In the AI Investment Brief today: CapEx updates and lease commitment breakdowns Anthropic co-founder Jack Clark recently said in a speech at the IMF that the singularity has begun: For many years, researchers and science fiction authors have forecast a future in which AI systems drastically increase the pace of overall scientific and technical progress, making things move so quickly that it is hard for humans to keep up. They call this the singularity. I believe that this year we have gained convincing evidence that it has now begun. This follows Anthropic’s claim that in August, 26% of its AI R&D was led by Claude, with a human supervising its work. In October, OpenAI posted 719 math manuscripts1 made by its internal model. Math and coding are two fields where a research loop can close without leaving the desk. But can the loop close in the rest of science? Subscribe The loop is real The idea is not new. Mathematician Irving John Good, who had worked with Alan Turing at Bletchley Park, argued that a machine smarter than us “could design even better machines; there would then unquestionably be an ‘intelligence explosion,’ and the intelligence of man would be left far behind.” The Gödel machine, a self-improving computer that can rewrite its own code better than its prior, was first proposed in 2003. In 2025, researchers at Sakana AI and the University of British Columbia set out to show that this was possible. Their agents iteratively improved their own code through a feedback loop, resulting in gains of 30 pp on SWE-bench and more than 15 pp on Polyglot, testing coding skills beyond Python. The idea has since been tested in other labs. A Gemini-powered agent called AlphaEvolve found a faster matrix multiplication kernel used for training Gemini, speeding up the kernel by 23% and cutting Gemini’s training time by 1%. In China, MiniMax reported that its M2.7 model worked on improving its own agent’s harness, skills, sampling and memory. Over 100 rounds of rewriting led to a 30% gain, per its internal evaluations. In each case, what was being rewritten was not the model itself but everything around it. Is it better than human work? In September this year, in what seemed like a milestone, an AI-built agent proved as good at improving other AI agents as a human-built one. It did that in what appeared to be half the steps. But the result was inconclusive: the differences between runs were greater than the difference between the AI- and human-built agent results. Nonetheless, this is increasing the chatter around recursive self-improvement (RSI) in AI. Google’s Sundar Pichai said that “you have RSI loops along with AI researchers in various aspects of model development.” Sakana AI published a paper on RSI through multi-agent collaboration, finding that after two cycles its system scored 1.2–1.6x better per output token than the base model across four research benchmarks. Ramez Naam challenges that view. He splits AI self-improvement into five overlapping types. The first four describe how autonomous the AI is; so far, only types 1 and 2 have been observed. The fifth type describes accelerating returns, and he notes that greater autonomy doesn’t guarantee a takeoff scenario. Instead, each round of self-improvement would need to deliver at least as much as the last. The results from Sakana, AlphaEvolve and MiniMax above might look like type 3 or type 4 autonomy. But in each case, the AI wasn’t updating its own weights directly, only the ancillary parts — the harness, the memory. And where Claude leads its own R&D, for now a human still supervises.
Scientists Estimate That Europe's Scorching Summer Heat Killed More Than 50,000 People in Urban Areas
The new research, which has not yet been peer-reviewed but was accepted for publication, suggests that climate change is responsible for two-thirds of the deaths
Cardiovascular Health in Girls and Women Compendium
Prevention and management of cardiovascular disease in women needs a new organizing framework. Cardiovascular disease remains the leading cause of death in women and accounts for 1 in 3 deaths, yet women’s cardiovascular care has been fragmented across specialties, life stages, and clinical guidelines, leaving female-specific risk under-recognized and inconsistently managed.
Suspect shot after reports of break-in at Ashland businesses, police say
Ashland Police shot someone early Monday morning after responding to reports of a break-in alarm at a business.The person, who has not yet been identified, was
Golden Joystick's "Ultimate Game of the Year" nominees are revealed, and votes for the winner are open until October 30
007 First Light, Resident Evil Requiem, Forza Horizon 6, and more titles have been revealed as candidates for Golden Joystick's 2026 "Ultimate Game of the Year", and votes for the winner are open
Multiple Vulnerabilities Identified in Component Used by Smile Digital Health’s Smile CDR
Four vulnerabilities have been identified in HAPI FHIR, the open-source Java library and server framework that implements the HL7 FHIR standard, that Four vulnerabilities have been identified in the HAPI FHIR open source component used in affect Smile Digital Health’s Smile CDR clinical data repository and health data platform.
Duval Dispatch:
What were the biggest issues that needed to be addressed by the Jaguars during their bye?
A virus that afflicts cows makes the jump to a human
For the first time, a human has been infected with the Shamonda virus, according to French officials. The World Health Organization says broader transmission is unlikely.
Anthropic's public S-1 sets stage for massive IPO debut
Anthropic, the company behind Claude, filed its public S-1 paperwork, setting the stage for an enormous IPO and shedding light on its finances.
Federal Water Tap, October 26, 2026: EPA Science Advisers Weigh In on Drinking Water Regulatory Process
The Rundown And lastly, the interior secretary says that Arizona’s Colorado River cuts are manageable over the next two years. “The allocation that’s been made, given the constraints we have and the commitments we have to make and the Law of the River, as it’s called, that this is a very positive outcome for Arizona […]
🚨 Breaking: Xavi Espart, out for two months for Barcelona
FC Barcelona have announced that Xavi Espart has suffered an injury. The defender had already been forced off against PSG last Tuesday, and then suffered an injury against Real Madrid.The Barça acade...
Liverpool have dodged a transfer bullet with one smart decision
Over the last few transfer windows, it feels like almost every single player in the world has been linked with a Liverpool move. It was clear after their fifth-place finish last term that some major c...
One Radio Source In Our Galaxy Has Been Producing Signals For At Least 20 Years That No One Can Explain
Still not aliens, but one of the weirdest things we have found in a sky where weird things are not in short supply.
In brief: Orlando Bloom, Elijah Wood joining 'The Gentlemen'
Netflix is rounding up more gentlemen. Tudum announced Orlando Bloom, Elijah Wood and Ed Speelers are joining stars Theo James and Kaya Scodelario for the third season of The Gentlemen, which is currently filming in the U.K. and Morocco. Also added to the series cast are Dexter Fletcher, Robert Carlyle and Bugzy Malone, who appeared in the 2019 film that inspired the Netflix series. Daniel Ings, who played the drug-addled older brother Lord Frederick “Freddy” Horniman to James’ criminal mastermind Eddie Horiman, told HATC magazine he will not return for the third season. Netflix has not confirmed this …The action-adventure series Fallout has inspired a new reality show. Prime Video has revealed Fallout Shelter: The Experiment, an unscripted competition inspired by the post-apocalyptic drama series and the video game universe. The show “invites everyday participants to test their aptitude for the apocalypse in Vault-Tec's state-of-the-art bomb-proof vault shelters," according to Prime Video. Contestants will “go head to head in a series of high-octane drills, psychological dilemmas and morally challenging behavior trials.” The winner walks away with a $1 million prize. Fallout Shelter: The Experiment will begin streaming in January 2027 … TNCMS.AdManager.render({region: 'fixed-big-ad-top-asset', slot: 1, fold: "above"}); Bravo renewed a slate of its reality shows ahead of Bravo’s Fan Fest on Saturday. New York-based In the City has been greenlit for season 2, while Next Gen NYC is coming back for a third season. For viewers seeking a little Southern charm, The Next Gen universe will be expanding with a spinoff based in Atlanta, and Southern Hospitality is moving forward with a fifth season. Premiere dates have not yet been announced … Copyright © 2026, ABC Audio. All rights reserved. Thank you for reading kmaland.comAt KMA, we attempt to be accurate in our reporting. If you see a typo or mistake in a story, please contact us by emailing kmaradio@kmaland.com.
Scientists solve mystery of 1,000-mile cloud floating on Mars
Space enthusiasts and astronomers have been tracking one of the Red Planet’s most fascinating atmospheric mysteries for years: a colossal plume officially known as the Arsia Mons Elongated Cloud (AMEC). AMEC was first discovered in 2018 and quickly became one of the most elusive answers for scientists. Researchers have now resolved this mystery using the […] Read the original article here: Scientists solve mystery of 1,000-mile cloud floating on Mars
2.9K views · 17 reactions | Over $10 billion has been spent so far on...
Over $10 billion has been spent so far on ads for the midterm elections, according to media tracking firm AdImpact. But who is paying for those ads? We dug into the data. https://wapo.st/4zKTGk7
National Academies Announce 2026 Winners of Eric and Wendy Schmidt Awards for Excellence in Science Communications; $640,000 Awarded
This year’s recipients of the Eric and Wendy Schmidt Awards for Excellence in Science Communications have been selected in recognition of their creative and original work in 2025 to communicate issues and advances in science, engineering, and medicine.
'Beetlejuice' star Ryan Stajmiger talks carving pumpkins and scaring
The national touring company's musical take on the classic Michael Keaton begins a Hobby Center run Nov. 3.
Worrisome chemical found in Bay Area, Santa Cruz creeks
A toxic compound has been found at worrisome levels in some watersheds in California.
Can a Bernie Sanders-backed progressive flip the Central Valley’s House seat?
Randy Villegas is a populist endorsed by national progressive figures like Sen. Bernie Sanders and Rep. Alexandria Ocasio-Cortez. Does his message meet Central Valley voters?
Rep. David Valadao talks Trump, immigration
“This district is not tougher than any I’ve ever run before. I’ve run in districts this tough in the past,” he said.
Worrisome chemical found in SF Bay Area, Santa Cruz creeks
A toxic compound has been found at worrisome levels in some watersheds in California.
Katie Fire Thunder’s campaign could help Montana seat a record number of Native women
Through grassroots organizing, political leadership and behind-the-scenes mentorship, their wins have been decades in the making.
TOC Predictions For The 2026-27 Basketball Season
TOC staff share their predictions for the Spartans upcoming season
Exclusive-US Political Candidates Tailor Messages for AI Models Used by Voters
By Mike Stone WASHINGTON, Oct 26 (Reuters) - US political candidates have been engineering their campaign messages to appeal to the AI chatbots that more voters have been using to answer questions about issues, and documents seen by Reuters have revealed some of their strategies. One Powerpoint ...
Why Justin Champagnie Is Earning Permanent Role in Wizards Rotation
The Washington Wizards are working through its rotation, but Justin Champagnie has made clear why he's an impact piece even with more competition
Potential buyer of Weiss and West Suburban hospitals has mixed track record
Insight Chicago owes tens of millions of dollars to the state, and its Bronzeville hospital has been cited for numerous safety issues.
Islanders News: Did not do Dallas
The Islanders were leaky all over in Dallas, almost like they have a declining defense outside of Matthew Schaefer. The 6-3 loss to the Stars was not surprising overall, but it did end a modest points streak and exposed some holes that Pete DeBeor has been working to cover. Islanders News Elsewhere
News Analysis: Trump says he's trying to entice Russia to negotiate. It doesn't appear to be working
Trump's break from long-standing tradition in U.S.-Russia relations was real, but it should not have been entirely surprising.
Lee Health: What it means to be a safety net for our community
At Lee Health, being a community-focused, nonprofit, safety-net health system is a point of pride. It is also a responsibility we take seriously every day and night. Throughout Southwest Florida, our patients, families, and neighbors count on us to be there when they need care. And for 110 years, we have been. Our teams are committed to carrying that legacy forward and continuing to earn the trust of our community.
Unlocking the mystery behind election polling
Political polling has been a staple of election season for hundreds of years. But recently, a lot of polls have missed the mark — widely. We take a look at how polling is done in Florida.
Groundbreaking Guidelines Released for Women’s Heart Health
The guidelines, which were authored by four major medical groups, are a framework for how hormonal changes up heart disease risk from puberty to after menopause.
This Offseason Will Hold Serious Considerations for These Three Yankees
It’s been weeks now since the 2026 New York Yankees season officially ended. This hasn’t stopped analysts from digging deep into what the future holds for the club. This offseason will involve some deep considerations about the structure of this club. Now more than ever, the Yankees and their ownership and front office want to spend …
Pro wrestling world mourns as former champion, actor dies at 79. Here’s the latest
He had been batlting several serious health issues.
MLS Could Use A Few Owners Acting Like Manchester City’s
In MLS, the rare clubs that have dared run afoul of the league's cumbersome roster regulations are also the ones that have been staples of the league's growth.
'Wheel of Fortune' Jim Thornton: FBI Never Contacted Witness in Pedo Chatroom Scandal
The woman who says she saw disgraced 'Wheel of Fortune' announcer Jim Thornton in a pedophile chatroom on a plane has NEVER been contacted by the federal agency that would investigate such matters -- the Federal Bureau of Investigation -- TMZ has learned.
‘Been a Problem for a Very, Very Long Time’ — Revisiting the Time Fox’s Pam Oliver Revealed the Health Battle That Impacts Her Sideline Reporting
NFL sideline reporter Pam Oliver has been a fixture in the business for more than 30 years, covering the league for Fox. At 65, she’s also one of the most experienced voices on the sidelines, most recently covering the San Francisco 49ers’ Week 7 matchup against the Atlanta Falcons.
Man charged with arson for fire at Puppy Love business
A 27-year-old man has been arrested and charged with arson after the Puppy Love business at 337 North Avenue caught on fire Saturday.
‘Resident Evil’ film resurrects horror game franchise
The first “Resident Evil” game came out in 1996, and since then, the franchise has been working to bring zombies, creatures and deadly outbreaks to life. For the newest piece,
Free walk-in vaccinations return to Yale Health as flu season looms
More than 3,600 flu and COVID-19 vaccine doses have been administered to Yale students this fall, as Yale Health continues its annual vaccination campaign ahead of the winter respiratory illness season.
World-First Cancer Vaccine Cuts Melanoma Recurrence or Death Risk by 42% in Landmark Trial
"This has not been achieved before in the history of cancer drug development."
Il Volo celebrates nearly 20 years of musical harmony
Longer than many marriages and most rock bands, the Italian singing trio Il Volo have been together for almost 20 years. They’ve gone from teenagers to 30-somethings while selling more
Trump critic Lula wins reelection in Brazil, securing fourth presidential term
Brazil’s President Luiz Inácio Lula da Silva, a vocal critic of President Donald Trump, has been reelected in a result that provides relief to critics of widening U.S. influence in
Helen Mirren bags Legend of Entertainment Award at Savannah Film Festival
Helen Mirren has been honoured as a Legend of Entertainment.
He's competed in 21 Hyrox races around the world: 3 top host cities
Lau Wen Loong has been competing in Hyrox races for two years and feels super fit. "I never imagined I could be faster than my younger self."
Johnson County Focus on Youth Fund promotes access to children’s mental health resources
This is an installment of a series exploring youth mental health. The Daily Iowan has received a grant and is partnering with the Solutions Journalism Network to explore the topic. The Johnson County Focus on Youth Fund has been promoting access to children’s mental health resources by providing funding for families who can’t afford services....
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo.
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo. This attack, which occurred on...
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo. This attack,
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo.
Attackers kill nurse, severely injure health worker responding to Ebola case in eastern Congo
The World Health Organization reports that a nurse has been killed and a health worker severely injured in an attack while responding to an Ebola alert in Congo.
Preparing for what’s next: Nursing insights on Future Ready Healthcare
New 2026 survey findings reveal how nurses view workforce sustainability, AI adoption, and patient communication, offering practical insights into what it takes to build a future-ready healthcare organization.
Business is booming for Giacinta’s at the Bridge
BRIDGEPORT – Since welcoming Giacinta’s Gelato & Caffe to their new location in the multipurpose Bridge at Bridgeport Exempted Village School District, the place has been a go-to spot for students and community members looking for that morning pick-me-up. Owner Audrey Brahler made some time between morning rushes of buyers to talk about the success […]
Trump invokes anti-Muslim rhetoric to attack El-Sayed at Port Huron rally
President Donald Trump has been telling crowds of supporters at rallies across the nation that they should vote in November as if he is on the ballot — a theme he invoked again in Michigan this weekend.
Vikings just proved why nobody wants to face Minnesota
The Minnesota Vikings have one real strength on their squad.
Early voting underway in Michigan
Early voting began Saturday, Oct. 24 in Michigan. County officials say the first day of early voting went well and more than half of mail-in ballots have already been returned.
Judges skeptical of Trump administration effort for force California to set aside mail ballots
A three-judge US Circuit Court of Appeals panel expressed significant skepticism Sunday over the Justice Department’s desire to inject itself into California’s midterm vote-counting process by forcing election officials to set aside the votes of suspected noncitizens who have been issued mail ballots.
Sunday Sports: Section 3 football matchups announced and more
Here’s a recap of your North Country sports this Sunday.
Shia LaBeouf waged one-sided feud with Hilary Duff, says ‘Even Stevens’ costar
Christy Carlson Romano says her ‘Even Stevens’ costar, Shia LaBeouf, was ‘beefing’ with Hilary Duff during their overlapping Disney Channel days: ‘He had to be the number one.’
Trump escalates rhetoric against El-Sayed as he tries to undermine Democrat in Michigan Senate race
The Republican president has been attacking El-Sayed's faith throughout the campaign and claiming his past statements and background show a sympathy for extremists.
Peoria business leader accused of DUI in deadly UTV crash
A business executive well known in the local sport community has been arrested on drunk driving accusations for a crash that killed a woman late Saturday night in rural Peoria County.
Serbia’s strongman leader Vucic concedes defeat to student-led movement in seismic political shift
It was a seismic political shift in the Balkan country where Vucic, who had been endorsed by Russian President Vladimir Putin and who denounced the student movement as a foreign-led attempt to unseat him, led with virtually absolute power for 14 years.
Bengals Shut out in Disastrous First Half vs Ravens
The Cincinnati Bengals are off to a first half they’d like to forget. Cincy trails the Baltimore Ravens 13-0 in Baltimore.The story has been the Cincinnati Bengals’ defense which has been struggling against this Ravens offense.The Ravens got off to a hot start as Zay Flowers took a 48-yard pass to the house from backup […] The post Bengals Shut out in Disastrous First Half vs Ravens appeared first on HEAVY.
Hinge damage suspected to be behind iPhone Duo screen cracks
The cause behind a repeating pattern in the way a very small amount of iPhone Duo screen cracks may have been discovered, with a failing element of the hinge believed to be causing the most damage.
Vučić concedes defeat in Serbian elections, says student movement won
The election was seen as a referendum on Vučić’s political dominance and the political system that has been in place in Serbia for more than a decade.
Barcelona host Real Madrid in anticipated Clásico clash
2026-10-25T20:12:58ZThere have been a few crunching tackles on both sides in the last few minutes and now the benches have taken exception as there is a little coming together in the center of the par...
‘I love spending time with them’: Lewis Hamilton opens up about Kim Kardashian’s kids
Lewis Hamilton and Kim Kardashian have been one of the most talked-about couples in sports and entertainment this year, but the seven-time Formula 1 world champion has rarely said much about the relat...
Inside 26-year-old’s club for million-dollar Chattanooga business owners
At 2nd American Restaurant on Thursday night, around 85 entrepreneurs who have scaled their businesses to at least $1 million in annual revenue sat to a family-style meal of beef cheek roast, airline chicken and the restaurant's signature bowl of mashed potatoes.
Union County Best of the Best Business of the Year Magnolia Renovations Joshua Andrews, owner
What was your reaction when you learned your business had been named Business of the Year?
What Will It Take for Rockies to Make World Series?
It's been since 2007 for the Colorado Rockies to be a part of the World Series. Is there any hope for a return to the Fall Classic?
MTSU named among Billboard's Top Music Business Schools for 12th year in a row
Middle Tennessee State University has been named a top music business school by Billboard for the 12th year in a row.MTSU's Department of Recording Industry mad
The rise and fall of Route 66
Route 66 was one of America's most popular highways, driving business to small towns. But today, the road and its people have been largely forgotten.
Browns Week 7 inactives: Who's in, who's out?
The Browns are the healthiest they have been in some time as they take on the Titans in Week 7.
Scientists Discover a Plant Compound That Could Help Stop Rheumatoid Arthritis Inflammation
Scientists have identified a plant compound that reduced joint swelling and inflammation in rats with experimental arthritis. The discovery offers a potential new direction for rheumatoid arthritis tr...
Packers Lose Defensive Captain Just Before Massive Showdown With Lions
Green Bay Packers defensive captain Zaire Franklin has been ruled out against the Detroit Lions, leaving Green Bay without both starting linebackers.
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
California Politics 360 full episode | Clash over voter rolls heads to court
On Tuesday, one week before the election, a federal judge will determine the next steps.
Their friend died of cervical cancer in 2020. Now, they advocate for women’s health in N.S.
Following the death of their close friend from cervical cancer in 2020, two women in Nova Scotia were left wondering how things might have been different had she been diagnosed earlier. Six years later, they have raised over $4 million to improve technology and infrastructure for women's health.
Modders Unlock GeForce RTX 20, 30 And 40 GPUs For Up To 2X Compute Gains
The compute barrierbbetween NVIDIA RTX Pro GPUs and NVIDIA GeForce GPUs has finally been breached.
Grading Iowa Football's Loss To Minnesota
This may have been Iowa's worst quarterback performance since the dreadful 2023 season.
Instacart Stock What Health Benefits Deal And $5 Million Settlement Mean
Instacart parent Maplebear has agreed to a US$5,000,000 settlement with U.S. authorities over past PERM hiring practices and has been selected by True Rx Health Strategists to power an employer funded healthy food benefit through Instacart Health Fresh Funds starting in 2027. The True Rx program positions Instacart within pharmacy benefit design and ties employer spend directly to clinically supervised food choices. The settlement adds compliance obligations, policy changes and monitoring...
Fernandes dropped: Man United name team to face Bournemouth
Manchester United have named their team to face Bournemouth in the Premier League, with captain Bruno Fernandes dropped from the side.Fernandes has been named among the substitutes at Old Trafford, in...