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Scientists discover brain switches that clear Alzheimer’s plaques
Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease. By stimulating these receptors in mice, scientists increased levels of a natural amyloid-breaking enzyme, reduced buildup in the brain, and improved memory-related behavior. Because these receptors are common drug targets, the findings could open the door to affordable pill-based treatments with fewer side effects.
Sports Card Show On Tap
Photo provided The Troop 6000 Sports Card Show is set to take place from 10 a.m. to 4 p.m. Feb. 21 at Vance Church in Wheeling. The event is sponsored by E&K Sports in Moundsville. There will be more than 35 vendors and door prizes, as well as visits from former Olympian Amy Gamble from […]
Achilles Running Shop celebrates 20 years of business
Achilles Running Shop first opened its doors two decades ago. Since then, it’s grown into more than just a retail store, becoming a hub for the local running community From first-time 5K runners to ex...
Kayla Lusane inspires students by taking learning beyond the classroom walls
For Kayla Lusane, teaching science at Barack H. Obama Elementary Magnet School of Technology is about more than textbooks—it's about opening doors.
Former Greater Cincinnati movie theater converted to indoor family fun center
Epic Entertainment Center opened Monday in Colerain Township, occupying the former theater space inside the mall.
Dee Snider says he’s ‘not dying’ after leaving Twisted Sister for health reasons
The 70-year-old Queens native is clearing up rumors that he was at death’s door amid the announcement of his retirement.
Leesburg residents, business owners skeptical of outdoor music permitting concept
The Leesburg Town Council is looking at a new individualized permitting process for outdoor music downtown, but business representatives and downtown residents alike were concerned about the potential changes at
After police shootings, Mamdani faces new pressure to overhaul NYC’s mental health crisis response
Two 911 calls for help ended with police at the door. Experts say dispatch rules and limited B-HEARD coverage leave few non-police options.
Try indoor golf, no-bake desserts at these new NJ businesses
Doughzerts offers edible cookie dough in Pequannock. Morristown Indoor Golf has membership options. Riverside Oral Surgery is in West Orange.
Jose Mourinho contract clause opens door to Real Madrid return
On Tuesday, Real Madrid will be reunited with former manager Jose Mourinho for the second time in a matter of weeks, as they face off against Benfica in the first leg of their Champions League play-of...
Indoor climbing becoming 'mainstream' sport
Climbing Hut Shrewsbury is seeing a surge in memberships with a 20% growth in people joining up.
Heavy air pollution and cloudy skies: The dusty haze covering Israel carries possible health risks
The Health Ministry and the Environmental Protection Ministry both issued warnings, advising all to avoid strenuous outdoor activities and close any open windows.
Who is the suspect in Nancy Guthrie's disappearance? What to know.
Authorities say they are searching for an unidentified person seen in doorbell camera footage. Here's the latest information.
WEST SEATTLE CRIME WATCH: Business break-in attempt
The report is from Jen, who says two people tried to break into The Void and Little Shop of Hairdos just south of The Junction early today, and sent images: 5:10 this morning, these two tried to break into The Void and the back door to Little Shop, met with too much resistance and interrupted by a neighbor. Appears to be the same MO and two ...
Mishawaka massage parlor closed by St. Joe County health department
According to a latter on the front door, New Feeling Massage was shuttered after a complaint and inspection.
First look at Epic Entertainment: Could it be a spark for Northgate Mall's redevelopment?
Epic Entertainment is an indoor adventure park, expected to open at Northgate Mall early next week. It could also provide a spark for Northgate's redevelopment.
Trump news at a glance: White House rejects climate science and opens door to more pollution
Administration revokes bedrock scientific determination that removes government’s ability to limit pollution from cars and trucks
Chicago police investigating business burglaries in Lakeview
A suspect broke into North Side businesses by breaking a side window or prying a rear door, stealing from cash registers, police said.
New calcium-ion battery design delivers high performance without lithium
Scientists at HKUST have unveiled a major leap forward in calcium-ion battery technology, potentially opening the door to safer, more sustainable energy storage for everything from renewable power grids to electric vehicles. By designing a novel quasi-solid-state electrolyte made from redox-active covalent organic frameworks, the team solved long-standing issues that have held calcium batteries back—namely poor ion transport and limited stability.
JUST IN: Rhodeside Grill to close after three decades in business
Long-time Arlington watering hole Rhodeside Grill will be closing its doors next week. The restaurant, bar and event venue at 1836 Wilson Blvd -- around the halfway point between Rosslyn and Courthouse -- will serve its last customers on Saturday, Feb. 21, co-owner Chris Lefbom confirmed to ARLnow. "Over the next ten days, we'd love
Historic Sheridan Fruit Company is closing its doors after more than 100 years in business
After 110 years in Portland, Sheridan Fruit Company is closing its doors. The independent grocer announced the closure Thursday confirming its final day will be on Friday, Feb. 13.
Rosalina closing for good after 13 years in business
A popular Italian restaurant in downtown Providence is closing its doors for good this weekend.
Madisonville supermarket to close after over 30 years in business
Sureway Supermarket in Madisonville is set to close their doors next month.
Android Auto will finally get this beloved Google Maps feature
It hopefully opens the door to even more options, too
What Homeowners Need to Know About Smart Home Cameras
A new Super Bowl ad is raising questions about the power of doorbell cameras.
'Further business goals' | Aggie Innovation Lab is opening doors for future entrepreneurs
Charlotte light rail stabbing could lead to changes in NC mental health law
NC lawmakers are prepping legislation that will address the revolving door between mental health and criminal justice systems.
Hands-on: Nothing ‘Essential Apps’ hit beta so you can vibe code your homescreen [Gallery]
One of the places AI has really made an impact is on app coding, opening new doors both for professionals...
What's next for Phillies after latest Zack Wheeler update?
Rob Thomson said Zack Wheeler likely won’t be ready for Opening Day. Dave Dombrowski left the door open for another starter.
Operator of Eddie Bauer stores in the US and Canada files for bankruptcy
Eddie Bauer LLC filed for Chapter 11 bankruptcy protection on Monday and hopes to sell about 200 of its namesake outdoor sportswear stores in the United States and Canada, blaming declining sales and supply chain challenges.
PNW-dedicated furniture chain closing all locations, going-out-of-business sale underway
A small furniture chain in the Pacific Northwest is closing its doors after nearly 40 years.
PNW-dedicated furniture chain closing all locations, going-out-of-business sale underway
A small furniture chain in the Pacific Northwest is closing its doors after nearly 40 years.
PNW-dedicated furniture chain closing all locations, going-out-of-business sale underway
Kasala Modern Home Furnishings, a small furniture chain in the Pacific Northwest, is closing its doors after nearly 40 years.
As a club promoter, he partied with Snoop Dogg. After taking on Ticketmaster, he sells cable door to door
Club promoter Tommy Dorfman lost everything after clashing with an entertainment giant. Fourteen years later, he's still waiting for his day in court.
Bracketology's revolving door of No. 1 seeds continues after Illinois loss
Houston's late-night win at BYU was rewarded by the CBS Sports Bracketology model
Super Bowl Ads Try to Overcome Tough Times With Health, Caring and the Usual Laughs
At a difficult time for America, Super Bowl advertisers ask viewers to take care of themselves and others — and maybe even crack a smile. Ring shows how neighbors can use their doorbell cameras to find lost pets. A Budweiser Clydesdale protects a bald eagle chick from the rain. Novartis touts a ...
Nature is the new thrill ride: Why wildlife is the travel moment Americans are chasing
Holland America Line reports that Americans are prioritizing wildlife and outdoor experiences in travel, favoring nature encounters over theme park thrills.
Physicists push quantum boundaries by turning a superfluid into a supersolid — and back — for the first time
Physicists saw excitons, a type of quasiparticle, undergo a reversible phase transition from superfluid to supersolid for the first time, opening new doors for studying extreme states of matter.
Family business bounces back after tragedy
SCRANTON, LACKAWANNA COUNTY (WBRE/WYOU) — A family business proved that good things come to those who wait. The local restaurant reopened after many years, and more than one tragedy closed their doors...
Brad Arnold, lead singer of Grammy-nominated rock band 3 Doors Down, dies at 47
Their debut album, "The Better Life," sold over 6 million copies
Record-Breaking One-Off Bugatti Brouillard Could Become the Most Expensive Bugatti Ever
A one-off aimed at a historic record Bugatti’s latest one-off, the Brouillard, steps onto the hypercar stage with the quiet confidence of a record-breaker. The brand’s tradition of bespoke excellence meets a bold new aesthetic, positioning this unique commission to potentially become the marque’s most expensive creation. Built on the proven underpinnings of the Chiron/Mistral architecture, yet transformed by distinctive craft, the Brouillard is both homage and innovation. A name born from equestrian legend More than a century ago, a striking white horse captivated Ettore Bugatti in Molsheim. That equine myth now informs the car’s name and its sensory identity. The result is an automotive portrait of athletic grace—surfaces that read like muscle, curves that suggest motion, and details that quietly speak of discipline and heritage. Embroidered horse motifs on door panels and seat backs echo the story, while a miniature glass sculpture of the steed crowns the shifter. Sculptural design with purpose The Brouillard’s silhouette favors sinuous surfaces over hard creases, allowing light to glide over its form like a tendon under skin. Aerodynamics inform elegance: an integrated ducktail replaces a deployable wing, cleansing the airflow and boosting stability at speed. Its stance is athletic, its volumes taut, and its visual language unmistakably Bugatti. “Sculptural, organic forms—like a tendon beneath the skin—hide immense power behind noble simplicity,” said design chief Frank Heyl, capturing the car’s philosophy in a single stroke. Craft elevated to an art The cabin embraces craftsmanship at an uncommon level. Custom-woven textiles from Paris introduce a discreet tartan pattern, while green-tinted carbon fiber nods to the exterior’s hue. A glazed roof creates a cathedral atmosphere, bathing the cockpit in natural light. A central spine appears to flow from exterior to interior, emphasizing continuity and structure. Highlights include: Custom textiles with subtle tartan motifs Green-tinted carbon fiber matched to the exterior finish A “cathedral” glass roof that elevates cabin ambience A sculptural centerline linking outside to inside Bespoke embroidery and glass equine detail W16 power at its absolute apex Under the sculpted skin, the final evolution of Bugatti’s 8.0‑liter, quad‑turbo W16 delivers a thunderous 1,600 hp at 7,050 rpm and 1,600 Nm of torque. This represents the pinnacle of nearly two decades of Bugatti engineering, honed to an ultimate state. The lightweight monocoque blends carbon fiber with aluminum, holding mass to around 1,900 kg for poise and control. Experts suggest the Brouillard could surpass the 282 mph (454 km/h) achieved by the Mistral, aided by more aerodynamic bodywork and the fixed ducktail. Whether or not it sets a new benchmark, its intent is clear: relentless speed paired with refinement. Exclusivity with an exacting timeline The commissioning process is intensive, with roughly 18 months of development leading to a 2027 delivery. Bugatti’s program limits itself to no more than two creations per year, ensuring focus and rarity. Each example leaves the atelier as a singular vision, shaped to the client’s collection and the brand’s ethos. An unveiling is planned for Monterey Car Week 2025, placing the Brouillard amid the world’s most discerning enthusiasts. Its patron is a European collector deeply invested in the Bugatti universe, from historic and modern cars to Carlo Bugatti furniture and Rembrandt Bugatti bronzes. A valuation poised to make history While Bugatti has not disclosed an official price, informed estimates place the Brouillard between €10 million and €30 million. Context matters: a series Mistral begins near €5 million, while the Brouillard adds profound personalization, sculptural changes, and a pace of production that keeps scarcity front and center. In an arena where uniqueness drives value, the path to a brand record is unmistakably open. What it signals for the marque The Brouillard crystallizes Bugatti’s dual identity: traditional savoir‑faire intertwined with boundary-pushing performance. It exhibits a narrative soul—the white horse of Molsheim—woven into modern materials and world-class aerodynamics. As a rolling statement, it reaffirms that the Bugatti idea is larger than speed alone; it is about story, craft, and the courage to pursue an ideal to its logical limit.
Ashburn’s All American Steakhouse is back in business
Good news to report today. The All American Steakhouse restaurant in Ashburn reopened its doors this morning – Saturday, February 7 – two days after it closed amidst a dispute with its landlord. The restaurant – long a staple of the Broadlands Village Center shopping plaza – closed suddenly and with no notice this past
Giannis Antetokounmpo's stake in Kashi opens new door to potential sports corruption
It may be time for Big Shield 2.
Blackpool business owners 'heartbroken' after huge fire
An indoor play area said the venue had been "destroyed" as crews from 15 fire engines tackled blaze.
Rocky’s Great Outdoors closing Burton store after 50-plus years in business
Rocky’s Great Outdoors, a staple in Burton’s business community since 1971, is going out of business.
Inside a family's custom multigenerational home in Oregon
Rather than living next door to her parents, Ana Ochoa and her family built one home with two distinct spaces that connect through a hallway.
Scientists found a hidden fat switch and turned it off
Researchers have discovered a previously unknown enzyme that plays a crucial role in fat production. By blocking it, they stopped weight gain, reduced liver damage, and lowered harmful cholesterol levels in animal studies. The finding opens the door to a new kind of medication that could tackle obesity, fatty liver disease, and cardiovascular disease all at once.
The US in brief: Showing seniors the door
The latest news in US politics, with coverage of Donald Trump’s second term.
New Business Licenses: 2.6.26
Chesterfield reports two law firms, a wellness business, an outdoor adventure group and more. (BizSense Pro required)
New business in Greece connects contractors with the community
Greece, N.Y. — A new co-working concept in Greece aims to better connect local contractors with the community.The Contractor Store has opened its doors on West
Family owned jewelry business in Albuquerque is closing its doors after three generations
ALBUQUERQUE, N.M. (KRQE) – A staple family-run storefront in Albuquerque is closing its doors after nearly 100 years in business. Butterfield Jewelers made the announcement last week on their socia…
Entertainment this week: Truckee Art Walk, Mardi Gras Masquerade and more
Friday, February 6 Kanekoa – 8-11 p.m., 14 State Route 28. Kanekoa returns to the Crown Room on Friday February 6th 2026. Doors 7PM, Show 8PM $20 ADV/ $25 DOS For more information, visit https://www.facebook.com/events/1371198487770284/....
This paper-thin chip turns invisible light into a steerable beam
Researchers have built a paper-thin chip that converts infrared light into visible light and directs it precisely, all without mechanical motion. The design overcomes a long-standing efficiency-versus-control problem in light-shaping materials. This opens the door to tiny, highly efficient light sources integrated directly onto chips.
Entertainment briefs | Black Humboldt hosts karaoke party
Black Humboldt is hosting a karaoke party tonight (Thursday) at 9 p.m. at Richards’ Goat, 401 I St., Arcata. Doors open at 8 p.m.
See how this Louisiana business became the largest outdoor advertising company in America
"Our audience is the driving public. As long as people get stuck in traffic, we’re in good shape."
Major firearms distributor serving thousands of retailers across multiple countries files for bankruptcy
Major outdoor sporting goods distributor Big Rock Sports files for Chapter 7 bankruptcy, potentially affecting over 20,000 retailers across multiple countries.
Fort Lauderdale bans drinking alcohol outdoors in entertainment districts
Drinking alcohol outdoors in Fort Lauderdale’s entertainment districts is now against the law.
Louisville business owner facing backlash after employee memo posted online
The owner told employees to "leave religion and politics at the door" after a police officer complained of disrespectful treatment, sparking criticism.
Clarest Health Launches "Clarest at Home," Closing the Gap in Medication Management from Facility to Front Door
VIENNA, Va., February 04, 2026--Clarest at Home Launch
SBA Shuts Doors On Small Business Loans To Green Card Holders In Latest Anti-Immigration Move
The policy, which goes into effect March 1, requires 100% of direct and indirect owners of loan applicants to be U.S. citizens or U.S. nationals residing stateside or within U.S. territories.
Fort Lauderdale bans open containers, outdoor drinking in Entertainment Districts
Natrona County Health Department christens new headquarters
CASPER, Wyo. — This week, the Natrona County Health Department officially opened its doors at a new Conwell Street location, marking the completion of a
Local business owners speak out after receiving racist, threatening letter
Hispanic business owners in Belchertown are sharing their story after someone left a racist and threatening letter on their front door after during their first week in town.
NCHSAA announces mass changes to the 2026 winter sports schedule
After consecutive winter storms, the NCHSAA has chosen to make alterations to schedules for basketball, swimming, diving, wrestling, and indoor track and field.
APT28 Uses Microsoft Office CVE-2026-21509 in Espionage-Focused Malware Attacks
APT28 exploited a Microsoft Office flaw to deliver MiniDoor and Covenant Grunt malware in targeted attacks across Ukraine and Eastern Europe.
Eddie Bauer stores at risk of closure as operator nears bankruptcy
The Eddie Bauer brand, best known for its durable outdoor apparel, is 106 years old. It was founded in Seattle in 1920 by outdoorsman Eddie Bauer.
Now anyone can tap Ring doorbells to search for lost dogs
Ring says Search Party helps find more than one missing pet a day.
Business year in review: what happened with Ann Arbor businesses in 2025?
From chain favorites opening on-campus locations to local staples expanding to long-standing businesses closing their doors, 2025 was an active year for businesses in Ann Arbor.
Are western New Yorkers spending more on digital entertainment as winter sets in?
As winter settles across Genesee County, colder evenings and shorter days are reshaping how households in Batavia and nearby communities spend their discretionary dollars. With outdoor options limited and heating
49ers hire Raheem Morris as defensive coordinator, AP source says
The San Francisco 49ers are hiring former Atlanta Falcons head coach Raheem Morris as their new defensive coordinator in hopes of finding a long-term solution to a revolving door at the spot. A person familiar with the decision said Sunday that Morris will join the Niners to replace Robert Saleh, who left San Francisco to take over as head coach for the Tennessee Titans.
Could Chargers trade for Tyreek Hill?
Tyreek Hill could be traded by this offseason. That could open the door for him to join the Los Angeles Chargers.
BIZBEAT: Entertainment-themed Airbnb opens doors in Jefferson City
A new gaming and entertainment haven is now open for business in Jefferson City, and visitors even have the option to stay the night.
Fairfield woman turns her Etsy business into a brick-and-mortar store
The building, painted blue with bright pink doors, reflects Ashby’s goal of creating a cheerful, welcoming space.
Albuquerque tamale business close to closing rebounds
Just days ago, a local tamale restaurant faced possible closure. Now, they’re selling out within hours, with lines stretching out the door.
Family-owned Seabrook restaurant shuts down after 25 years in business
A longtime Seabrook restaurant is preparing to close its doors after more than two decades of serving the community. Las Anita’s, a family-owned restaurant that has operated in Seabrook for 25 years, announced on Facebook that it would be shutting down. The restaurant’s final day of business was Saturday, Jan. 31.
Aurora restaurant concerned new city construction project may hurt nearby businesses
Casa Vallarta Mexican Restaurant in Aurora has survived a lot of trials since it opened its doors in 1998. It is now preparing for yet another challenge as a major construction project is set to begin nearby.
Jeannot ‘all business’ facing Lightning at Stadium Series with Bruins
Forward played parts of 2 seasons for Tampa Bay, also went up against former team outdoors with Predators
Fort Wayne businesses closed in solidarity with ‘ICE out’ day of action
On the front doors of these businesses are signs signaling to customers that their store is not open. Local vegan and gluten-free bakery Good Bread was one of those businesses.
Many Richmond businesses close as part of nationwide general strike against recent ICE actions
After many businesses throughout Central Virginia were forced to shutter their doors or alter their hours due to impacts from the winter storm, many have decided to close again on Friday, but for a…
Some Seattle-area businesses closed as part of nationwide strike
Dozens of Seattle-area shops and restaurants shuttered their doors or are donating proceeds on Friday as part of a "National Shutdown."
Portland businesses join national ‘ICE Out’ protest, close doors Friday
Phoenix business owners join nationwide ‘Ice Out of Everywhere’ strike
Business owners in the Phoenix metro area are closing their doors Friday to support the “Ice Out of Everywhere” movement that began in Minnesota.
Phoenix businesses join nationwide 'ICE Out' to protest immigration raids
Several local businesses across the Valley will close their doors Friday, Jan. 30, as part of a nationwide "ICE Out" shutdown to protest recent federal immigration operations.
Businesses in the Triangle feeling the effects of winter weather
Local businesses are feeling the effects of the winter weather, especially when they have to close their doors. Many business owners told WRAL News that weekends are the busiest time, so having their doors closed and with no customers two weekends in a row is hurting their margins.
New radon story map explains how it enters the indoors, health risks and how to fix it
The latest story map published by EGLE provides a detailed look at radon.
Multiple Upstate NY businesses to close Friday for national anti-ICE shutdown
Multiple cafes, restaurants and shops across Upstate New York will close their doors Friday in protest of recent federal immigration enforcement.
Trump directs team to beef up his public schedule to combat questions about his stamina
Vague descriptions of presidential signing ceremonies, policy meetings and industry executive sit downs — mostly behind closed doors — began peppering President Donald Trump’s public schedule at the end of last year.
Pulaski County Sports and Entertainment unveils new logo for Sportsplex
Pulaski County Sports and Entertainment unveiled a new logo on Wednesday for the Pulaski County Sportsplex, a transformative new indoor sports complex that will serve as a premier destination for athletic competition.
Pulaski County Sports & Entertainment Unveils Official Sportsplex Logo
New Facility Designed to Serve the Community and Welcome the World Pulaski County, Virginia – Pulaski County Sports & Entertainment is proud to unveil the official logo for the Pulaski County Sportsplex, a transformative new indoor sports complex that will serve as a premier destination for athletic competition while providing a year-round recreational asset for […]
Recognize Data Privacy Day by protecting your small business from cybercriminals
Your small business likely has had many milestones. Hiring your first employee. Opening your doors for the first time. Making your first sale. But some milestones you’d probably rather avoid — like experiencing your first cyberattack. Think you’re too small to target? Think again. Cybercriminals target companies big and small, so this Data Privacy Day keep your business’s data (and your customers’ data) safe by reviewing the FTC’s updated resources at ftc.gov/cybersecurity.
Vacant Houston properties burn four times, threatening established business next door
Four fires in two years. 50% of customers gone. And the city-cited buildings just burned again. This Westheimer restaurant owner says enough is enough.
Evansville business agrees to put up a fence and stop burning materials
HENDERSON, Ky. (WEHT) — An Evansville business has agreed to put up a fence and stop burning materials in order to reopen their doors. The Evansville Area Plan Commission met on Tuesday. One of the items on the docket was the final reading of a rezoning ordnance for American Tree Experts. The business operates along […]
Science foundation targets National Center for Atmospheric Research for breakup
A letter from the federal agency opens the door to privatizing the Boulder research center.
Burning Wood Indoors May Be a Bigger Health Risk Than You Think
By I. Edwards HealthDay ReporterTUESDAY, Jan. 27, 2026 (HealthDay News) — Lighting a fire on a cold winter night can feel cozy. But a new study suggests it may also harm your health, even if you don’t burn the wood yourself. Researchers at Northwestern University found that home wood burning is responsible for about 22% of outdoor ...
Boxes of tissues, binge-watching and DoorDash: How you’re making it through a record-breaking flu season
When CNN asked for your flu stories, we received hundreds of written responses from people stuck in bed, binge-watching TV, working from home and trying to keep their kids under control — all while feeling terrible.
New golf performance business to blend simulators, high-tech short-game complex
A new indoor golf performance business in northeast Sioux Falls is nearing its opening.
Indoor health risks rise during winter weather
WDBJ7 spoke with the VDH State Health Commissioner about increased health risks while indoors.
Trump's war on immigration entangles business in PR disaster and the literal site of contested arrests
In Minneapolis, hotels, restaurants and other businesses have temporarily closed their doors or stopped accepting reservations amid widespread protests.
Immigrant-owned and staffed businesses frightened by ICE activity in Maine
Some are temporarily closing their doors or making contingency plans.