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How geopolitical rifts cut scientific collaboration
Researchers have measured how worsening geopolitical relations hobble scientific collaboration, at last quantifying the impact of rifts between governments on cooperation between labs. Over the last decade, a tenser world has thrown up new barriers to cross-border science. Collaboration between the US and China has dimmed as the two countries have sunk into an ever-deeper rivalry. Links between Russia and Europe have collapsed following Moscow’s full-scale invasion of Ukraine. But while a concern, the magnitude of the damage is less than might be expected. For all the geopolitical turmoil of the last decade, international scientific collaborations are near a record high. “Some part of the story is positive,” said Shreyas Gadgin Matha, a social scientist at Harvard University and an author of the new study. “Research collaborations are largely resilient.” Matha and colleagues looked at data on cross-border research papers and patents in the period 2000-23, and analysed how they were impacted by countries’ political relations, as measured by how often states voted together in the United Nations. They found that when states drift apart at the UN by the median difference in votes between all countries, joint scientific papers decline by 3.1% over the next three-year period. To put that in context, over the last decade, the US and China have diverged by around a third of that difference in votes every three years. In other words, on average, it takes quite a significant diplomatic rift even to trigger a small single-digit percentage drop in joint papers. “In the short term, even something like a 3% reduction [in joint papers] is, in some ways, not that big of a number,” said Matha. Research remains more international than ever, according to an analysis extending to 2023 released by the Organisation for Economic Cooperation and Development (OECD) in 2025. We’re still living in an era of unprecedented scientific globalisation, the analysis says, with 27% of papers in OECD countries written across borders. In 1970, just 2% of articles had authors from different countries. Longer-term damage?However, this trend towards increasing international collaboration “has lost momentum and might be partly breaking down,” the OECD analysis says, largely due to a fall in the intensity of US-China joint papers since 2018. Matha and his colleagues stressed they are not complacent about the global science system. For now, “it's pretty resilient,” said co-author Muhammed Yildirim, director of academic research at Harvard’s Growth Lab. But if links are weakened, through the denial of study visas, for example, then this could have a much longer-term effect, cascading through generations of scientists, he added. Related articlesChina becomes Russia’s biggest collaborator after war decimates science ties with the west US scientists prefer German to Chinese collaborators, study finds Horizon Europe is now truly global. But what comes next? Another finding of the study, Burning bridges or bridging divides: Geopolitics and collaboration in research and innovation, is that trust appears easier to destroy than create.The hit to scientific collaboration when countries drift apart is around three times as big as the growth in joint papers when they move closer, the paper finds. “It's far easier to break these ties than to mend them, and that that also perhaps has some larger policy lesson,” said Matha.PatentsThe results around patents were less clear cut. Some methods of analysis found a statistically significant link between a diplomatic rift and a drop in co-patenting, but others did not. According to Yildirim, patents with cross-border inventors are often developed by multinational companies, which may have invested heavily in global R&D facilities, so are less likely to change how they operate simply due to a change in the geopolitical weather. “That's why we might not be seeing the effect immediately in technology,” he said.By contrast, researchers might be more sensitive to geopolitics, because visa policies can quickly affect who meets who at academic conferences, he went on. International collaboration on patents is much lower than for academic articles, the study shows. It peaked at around 10% in 2010, and has since fallen back to around 8%. This could be because China dramatically ramped up domestic patents in the 2010s, said Yildirim, squeezing the international share.
NYU Grossman’s next psychiatry chair on expanding mental health services at Langone
This month, NYU Langone Health tapped William Gordon Frankle to chair the Department of Psychiatry at NYU Grossman School of Medicine. With experience leading psychiatry care at NYU Langone Hospital—Brooklyn, Frankle is now slated to lead services across Manhattan, Brooklyn, Long Island. In his new role, he described plans to increase NYU Langone’s suicide prevention...
Arsenal consider €80m move for Como midfielder Paz
Arsenal are considering a move to sign Como midfielder Nico Paz next summer and have expressed initial interest.Paz is on Arsenal’s radar ahead of the 2027 summer window as Mikel Arteta looks to imp...
Mariska Hargitay's 2026 has been busy. Next up is her Emmys host gig
Mariska Hargitay has been a mainstay on television as Capt. Olivia Benson on "Law & Order: Special Victims Unit." Now, she's taking on TV's biggest night as host of the 78th Emmy Awards.
Special interests spend millions boosting Becerra in governor's race
Companies and special interest groups with some of the diciest issues expected to land on California's next governor's desk are among the top financial backers of Democrat Xavier Becerra, the gubernatorial front runner.
Healthcare AI’s next test is integration
While advanced AI excels at processing clinical data, healthcare's true test lies in overcoming deeply fragmented administrative workflows.
DFB Cup home match against Magdeburg scheduled
The kick-off time for FC Bayern’s next DFB Cup outing at the Allianz Arena has been confirmed. As announced by the German Football Association on Thursday, the holders’ home tie against Bundesliga...
Harvey Higgins - who is breakthrough Rovers striker?
After losing Igor Tyjon to Arsenal, Blackburn have promoted striker Harvey Higgins as their next young forward in line.
Apple Announces macOS Golden Gate Release Date
Apple this week announced that macOS 27, also known as macOS Golden Gate, will be released to all users with a compatible Mac on Monday, September 14. iOS 27, iPadOS 27, watchOS 27, tvOS 27, and visionOS 27 will be released on the same day. macOS Golden Gate features Siri AI, design improvements, performance enhancements, and more. A developer beta has been available since June, while a public beta followed in July, and now the update will be widely released on September 14.
J-50 design team reveals leapfrog tech for China’s next-gen stealth fighters
The aircraft are expected to have futuristic systems for self-flying and large-scale drone wingman squads.
Liverpool finally given green light to sign their next Fabinho
The last couple of years have been full of heavy spending for Liverpool. The Anfield outfit have now spent well over £500 million on trying to improve their ranks and, although things finally came to...
Washington residents face average 22% health insurance rate hike in 2027
Washington residents who buy their own health insurance are set to pay more next year, with rates increasing by an average of 22.2% in 2027.
Memorial completes the comeback to beat North
EVANSVILLE, Ind. (WEHT) — After trailing 1-0 through the first half, Memorial boy’s soccer team scored two in the second half to beat North on the road. Next, the Tigers will host Castle on Wednesday, September 16th. While the Huskies face Washington at home on Saturday, September 12th.
Seahawks Get Concerning Sam Darnold Injury News Amid Patriots Game
After one series, there’s concern about Seattle Seahawks QB Sam Darnold. After a 3rd-and-6 play, Dre’Mont Jones sacked Darnold for a five-yard loss, but after the play, he limped off the field. When the Seahawks were on defense, Darnold went into the blue tent to examine him. In the very next series, backup Drew Lock […] The post Seahawks Get Concerning Sam Darnold Injury News Amid Patriots Game appeared first on HEAVY.
Dianna Russini Career News Emerges Hours Before Patriots-Seahawks Game
Where is Dianna Russini now? Find out the latest news and rumors on Russini's next move amid the Mike Vrabel fallout. The post Dianna Russini Career News Emerges Hours Before Patriots-Seahawks Game appeared first on HEAVY.
Viewpoint: Unlocking Europe’s wildfire data
Europe is already investing in the science, technology and infrastructure needed to understand, prevent and fight wildfires. Copernicus provides satellite-based Earth observation and environmental information, while the European Forest Fire Information System provides information on fire danger and forest fires across Europe. Weather and climate systems add forecasts of heat, drought, wind and humidity; historical fire databases show where fires have occurred; and researchers generate increasingly detailed knowledge about fuels, fire behaviour, forecasting, modelling and risk management. Meanwhile, new European research projects are adding digital twins and other tools to this growing ecosystem.However, these data do not necessarily sit together, nor are they necessarily described, structured or governed in ways that allow them to be used together. Much of the information is public, but some is commercially held. Some is sensitive. Some is subject to legal, security or operational restrictions. Even when data can be legally accessed, different systems may use different formats, terminology and rules.Europe therefore faces an unusual paradox: we have vast amounts of relevant information to respond to the wildfire challenge, but not the means to bring it together. For example, a wildfire researcher or emergency service might need to ask whether a particular combination of vegetation, drought, wind and topography has historically been associated with rapid fire spread. The relevant information may exist in several institutions, using different systems and subject to different conditions of access.The challenge is to conduct an authorised analysis that interacts with these sources, combines the results and respects the rules imposed by each data custodian.An important part of the answer can be found in the Fair principles, the idea that data should be findable, accessible, interoperable and reusable. Developed more than a decade ago, these principles have become a central reference point for modern data stewardship, making it easier for people and machines to find data, understand what it means and determine whether it can be reused.Readability by machines is essential, since AI systems will be key to meeting the data challenge. Bring analysis to the dataThe proposition is not to give an AI system unrestricted access to sensitive databases. Quite the opposite. The goal is to make it possible for approved algorithms to go to the data, rather than requiring sensitive data or large datasets to be copied to wherever the analysis happens.Imagine an analysis asking a series of questions of different data stations. At one station it might examine weather and climate data; at another, historical fire records; at another, experimental measurements of fire behaviour. The algorithm does not need to download everything. It can operate within the environment permitted by each data custodian and return only the results that the rules allow to leave.This is sometimes described as data visiting, and related approaches already exist in areas such as federated analysis and federated learning.Sensitive data should therefore not be treated as a free-for-all for machines. This requires appropriate governance at multiple levels. Access needs to be authenticated and authorised. The purpose of an analysis should be defined. The code or model being run should be controlled. Data custodians should be able to specify what can be queried and what results can leave their environment. Activities should be auditable and human oversight should remain where the consequences require it.In other words, the objective is not to trust AI with the data. It is to design systems in which AI never has more access than it needs.As open as possible, as closed as necessaryFair data should also not be confused with open data. Some wildfire data should be openly available. Other information may legitimately need to remain restricted because it concerns critical infrastructure, security, commercial interests, privacy or operational capabilities. The principle should be: as open as possible, as closed as necessary.The important point is that restricted data should not automatically become unusable data. If machines can discover what information exists, understand its meaning, establish where it came from and determine the conditions under which it can be used, authorised analyses can potentially be carried out without the underlying data ever leaving the environment in which it is protected.Restricted data can still be Fair and machine-actionable.This is also an important question of data sovereignty. European institutions should not have to surrender control of their data to a handful of technology platforms in order to benefit from AI. Nor does Europe need to start again by building one giant repository for every piece of wildfire information. The better approach is to connect what already exists.This is the principle behind emerging approaches such as Tryangle, developed through the Leiden Initiative for Fair and Equitable Science. Rather than creating another centralised data warehouse, the approach seeks to provide an interoperable layer through which approved algorithms can visit distributed data sources while respecting the rules of their custodians.In this way, a data station can remain where it is. Its custodians can retain control. Existing databases and applications do not have to be abandoned. What changes is their ability to communicate with other systems through common, machine-readable descriptions, access rules and interoperability mechanisms.But approaches like this need data that meets the Fair principles. Only then can an interoperable ecosystem safely begin to turn fragmented information into collective intelligence.Data infrastructure is wildfire infrastructureThe implications of this approach are entirely practical. Firefighters could gain better intelligence about local and evolving risks. Land managers could test prevention strategies using more comprehensive information about fuels, weather and past fires. Researchers could compare evidence across ecosystems without repeatedly moving huge datasets between institutions. Smaller regions and resource-constrained teams could access analytical capabilities without having to build large data infrastructures themselves.Europe is already investing heavily in satellites, databases, research programmes, forecasting systems and scientific expertise. The question is whether we will connect those investments well enough to turn them into actionable intelligence.That requires policymakers and funders to treat data infrastructure as seriously as physical infrastructure. Data generated or supported through European public funding should be Fair, verifiable and machine actionable by design, wherever legally and ethically possible.Related articlesData Corner: Europe’s burning need for wildfire mitigation researchClimate monitoring must remain a global enterprise, experts sayIn practice, that means funding not only the production of data, but also the infrastructure that makes data usable across systems: metadata, provenance, interoperability, access mechanisms and governance. Where data must remain restricted, we should ensure that it can still be securely discovered, verified and used for authorised analysis.Initiatives such as the European Open Science Cloud offer an existing framework through which these principles can be put into practice. What is needed now is to accelerate implementation and make them a standard part of how Europe funds and builds research and innovation systems.We do not need another generation of disconnected databases. The data is already there. The opportunity is to make it work together, securely, responsibly and quickly enough to help prevent the next fire, rather than simply document the last one.Jean-Claude Burgelman is professor emeritus at the Free University of Brussels (VUB) and editor-in-chief at Frontiers Policy Lab. For more than 20 years he held leading roles in research and innovation policy at the European Commission.
Closing health workforce gaps for emergency response: the Western Pacific steps up
Over 100 health emergency experts from 56 institutions across 21 countries in the World Health Organization (WHO) Western Pacific Region who are part of the Global Outbreak Alert and Response Network (GOARN) concluded their annual regional partners’ meeting with a commitment to bridge gaps in emergency workforce capacities and advance regional emergency readiness and resilience.Co-hosted by WHO and the Korea Disease Control and Prevention Agency in the Republic of Korea, the two-day event aimed to strengthen the Region’s collective ability to detect, prepare for and respond to health emergencies.Partners mapped capacities and priority technical gaps across the Region — including cybersecurity and critical infrastructure resilience; water, sanitation and hygiene (WASH) and environmental health; biological emergencies, nuclear emergencies, and nuclear and radiological security.The result: a renewed commitment to close these gaps by working together through shared expertise and coordinated action. Advancing the Global Health Emergency CorpsReflective of regional solidarity and partnerships in action, GOARN – which is coordinated globally by WHO - enables a stronger, better-connected emergency health workforce that is ready to surge wherever and whenever requested by WHO Member States.This year alone, GOARN partners across the Western Pacific have supported nine experts on six missions - from measles outbreaks in Viet Nam to HIV outbreak response in Fiji - providing surge support in epidemiology, surveillance and clinical case management.Photo: Participants at the Global Alert and Response Network (GOARN) Partners Meeting 2026. Credit: KDCA/Shin Dong Myoung“GOARN partners across the Western Pacific and globally have repeatedly demonstrated the power of what we can do collectively, when we join forces, share expertise and build on each other’s strengths,” noted Dr Gina Samaan, WHO Regional Emergency Director for the Western Pacific, in her opening remarks at the gathering. “Let us continue to forge long-term partnerships grounded in mutual respect that will protect the Region for generations to come. We are smarter, faster and infinitely stronger when we work together,” she added.Reiterating Dr Samaan's call, Dr Seung-kwan Lim, Commissioner of the Korea Disease Control and Prevention Agency, emphasized the value of GOARN: “The Republic of Korea is pleased to stand alongside our regional partners in building an emergency workforce that is ready and resilient. GOARN turns national expertise into regional readiness - catalysing national strengths into collective resilience.”GOARN advances the Global Health Security Action Framework (GHEC) initiative by “convening, connecting and capacitating” regional leaders and surge workforce – “the three Cs”. Years of GOARN leadership and outbreak response training programmes have cultivated a deep bench of fit-for-purpose, seasoned outbreak response experts and forged an alumni network of emergency leaders worldwide. The Western Pacific network alone has now grown to 94 partner institutions across 19 countries. Photo: Participants at the Global Alert and Response Network (GOARN) Partners Meeting 2026. Credit: KDCA/Shin Dong Myoung Putting partnerships into practiceDuring the Regional Partners’ Meeting, health experts identified and catalogued the technical expertise currently available across the Western Pacific Region, so that the right skills could be better matched quickly to needs wherever emergencies occur.Three priority areas emerged for further strengthening:Cybersecurity and critical infrastructure resilience - protecting essential systems, including healthcare networks, from digital disruptions.Water, sanitation and hygiene (WASH) and environmental health - reflecting the ongoing nexus between climate change and health.Biological emergencies, nuclear emergencies, and nuclear and radiological security - requiring specialized technical capability that remains limited across many national response systems.Meeting participants reaffirmed their commitment to strengthening workforce capacities in the Region, with a particular focus on these three areas, and to working collectively to better prepare the Western Pacific for the next health emergency.Photo: Dr Gina Samaan, WHO Regional Emergency Director for the Western Pacific, delivers opening remarks at the Global Alert and Response Network (GOARN) Partners Meeting 2026. Credit: KDCA/Shin Dong Myoung“GOARN is truly turning preparedness into action - giving our Region the surge capacity it needs for fast, coordinated response when it matters most - and building more resilient health systems along the way,” said Dr Samaan. “As health emergencies mount in this age of permacrisis, emergency preparedness and response must be woven into the fabric of health. This is not an option, but an imperative as we seek to achieve health for all.”____ About GOARNThe Global Outbreak Alert and Response Network (GOARN), coordinated by the World Health Organization since 2000, strengthens global health security by advancing preparedness for and response to public health emergencies. The network brings together more than 390 institutions, including national public health agencies, technical organizations and nongovernmental partners, to support coordinated international action during outbreaks and other health emergencies. There are 94 GOARN partners in the Western Pacific Region (as of August 2026), accounting for approximately 25% of global partners. For more information and media interviews, please contact: WHO Western Pacific Communications: wprocom@who.intAra Johannes: johannesa@who.int
Rhode Island could see a political wipeout next week
If Governor Dan McKee, Lieutenant Governor Sabina Matos, and Mayor Brett Smiley all were to fall, it would amount to an unprecedented upending of Rhode Island’s political establishment, and a massive rebuke that could signal a significant shift in the state’s political landscape.
New AI health tools need ‘L-plates’, says UK review
Proposals following national consultation on health tech regulation call for live monitoring as AI moves deeper into patient care
Apple announcement recap: new foldable iPhone, Watch, and AirPods
Apple's new CEO, John Ternus, unveiled the next generation of iPhones, Apple Watches, and AirPods during Wednesday's Surprise and Shine event.
Motorola teases wide Razr Fold as its ‘next move’ in response to iPhone Duo debut
Apple’s iPhone Duo announcement has triggered a couple of companies, and it’s apparently warranted at least one teaser for even...
Cancer center services moving to Owensboro Health Regional Hospital
The changes are expected by early summer of next year.
NASA’s Swift Observatory Resumed Science Observations, At Least For Now
The satellite will be falling back to Earth within the next two months.
Science, Technology, Engineering, Math … STEM in action at next Placer County Navy League meeting
The Placer County Council of the Navy League is meeting Monday, Sept. 21.
macOS Golden Gate Release Candidate Now Available
Apple today seeded the release candidate version of macOS Golden Gate, with the update coming a week after Apple seeded the eighth beta. The release candidate is the final version of macOS Golden Gate that developers and beta testers will get before the software sees a public launch. Tessters can download macOS Golden Gate by going to System Settings > General > Software Update. Beta Updates will need to be enabled, and a free developer account is required.
Private Equity’s Next Focus: Profitable Niche Businesses
After years of targeting industries like veterinary practices and plumbing companies, experts say private equity is focusing on more profitable niche businesses.
Launching a business school at Catholic high school in Victoria
It was an offer he couldn’t refuse, the culmination of his career. Scott Breimhorst couldn’t pass up the invitation to lead a new business school for Holy Family Catholic High School in Victoria. The 53-year-old father of three recognized an opportunity to bridge education and business, tapping into his vast network and cultivating the next generation of executives and entrepreneurs.
UGA’s Buell Grows Discovery and the Next Generation of Scientists
Not the Plan but the Right Path
Should the Miami Heat Sign Former National Champion?
As Memphis prepares to waive Walter Clayton Jr., the Miami Heat could leverage their proven developmental system to transform the former Florida star into the next high-impact guard.
Boston Dynamics spinoff looks to build robots for entertainment
Dynamic Creatures is building theme park robots on Chinese hardware. Europe's own social robotics champion was sold to a Shenzhen buyer last year.
Georgia Fans Are Absolutely Furious About This
Georgia football fans will pay for a lot of things. Tickets. Parking. Donations. Merchandise. Streaming subscriptions. Apparently, game highlights are next. Georgia promoted its traditional “Victory Highlights” video following its 63-3 destruction of Tennessee State , except there was one massive catch. The full video was placed behind the Glory Glory subscription service, which starts…
Apple releases iOS 27 RC ahead of public launch
Apple has released the first iOS 27 release candidate for testing. The update brings Apple’s next major iPhone software release...
Business tidbits: Charlotte Russe to open in Valley Mall, new restaurant in Selah
A San Francisco-based retail chain specializing in clothing for women in their teens and 20s is opening next week at Valley Mall in Union Gap.
The Apple Watch Ultra 4 is ready for the new Siri
The Apple Watch Ultra 4 is ready for your next adventure.
Apple unveils AirPods 5 with upgraded noise cancellation, more
Today during its iPhone 18 Pro event, Apple announced the next generation AirPods 5 with improved active noise cancellation.
The ‘Sacred Science’ has another way to deal with death
The next time someone asks why you’re on your phone so much, tell them you’re just working on your Immortality Project. It’s a concept from cultural anthropologist Ernest Becker’s 1973 book “The Denial of Death,” which posits that most of what humans spend our time on is meant to pretend the inevitable isn’t waiting for […]
Swan Town Creative Announces Inaugural Build Business Better Conference for Established Business Owners
A live virtual conference featuring an all-woman lineup of business experts, built to help established business owners explore what's possible and decide what comes next.Marietta, GEORGIA, Sept. 09, 2026 (GLOBE NEWSWIRE) -- Swan Town Creative, a business advisory and consulting firm, announces the inaugural Build Business Better Conference, a two-day live virtual event taking place October 21–22, 2026. Designed primarily for business owners with three or more years of experience who have moved b
NovaOne Launches Next-Generation Platform Uniting Behavioral and Physical Health
NovaOne today announced general availability of its next-generation solution: a modular platform, uniting purpose-built preventive tools, clinically validated assessments, an AI care navigator with deep human clinical oversight and a curated network of evidence-based specialty providers. One platform for integrated preventive and curative healthcare.
Quantum Theatre names next artistic director as founder prepares to retire
Katie Brook to take over as artistic director of Quantum Theatre in Pittsburgh, succeeding founder Karla Boos who is retiring after 36 years.
Carrick on Shaw, 'magical' Champions League and Sabah
Manchester United boss Michael Carrick has been speaking to the media before Thursday's Champions League fixture against Sabah at Old Trafford (kick-off 20:00 BST). Defender Luke Shaw has been given an extra recovery day and they will know by Thursday whether he will be in the squad. Dutch defender Matthijs de Ligt has trained well and is "on good track" to make a return soon but United have to "get the balance right" for the next steps.
Bayern Munich not yet sure if Michael Olise will extend
FC Bayern will give Olise until next year to make a decision.
Town Hill VIS welcomes new governing board
The new board's first official meeting will be held next Wednesday, Sept. 16, at 6:30 p.m. The meeting will be held in the Town Hill Community Hall, next to the
Cosmos Update
Become director of a space station, join a galactic alliance, construct a space base and discover deep-space marvels in No Man's Sky Cosmos. Navigate space with a new star system map, strip colossal hulks for parts before hull integrity fails, recover and haul physical salvage to remote space outposts, celebrate 10 years of No Man’s Sky in the Our Journey Continues expedition, and much, much more
Gracenote Expands AI Product Roadmap with Sports MCP Server, Entertainment SLM and Agents
/PRNewswire/ -- Gracenote, Nielsen's content intelligence business, today unveiled the next phase of its AI product roadmap. Anchored by its Video Model...
RUNC: Advaith Cheruvu
The senior strives to make next-generation computing technologies more powerful and practical.
GameSquare Enters Definitive Contribution Agreement to Acquire Sports, Music and Entertainment IP Assets from FanEngine
("FanEngine"), a technology and media asset consolidator that collectively enables sports, music and entertainment IP owners to build direct relationships with fans and monetize those relationships through gamification, brand integration, events, content, commerce, and experiences.The Transaction is expected to be immediately accretive to profitability and represents the next step in GameSquare's strategy to build a differentiated, end-to-end platform spanning audience analytics, creators, agenc
How the Texas Attorney General Got This Way
Greg Abbott and Ken Paxton transformed the role from bureaucrat to culture warrior. What comes next?
Peter Stanbury on the business case for sustainablity in drinks
As we count down to next month’s Sustainability in Drinks event in London (October 21), Dr Peter Stanbury, research director of the influential Sustainable Wine Roundtable , makes the case for why all drinks companies should be taking not just taking sustainability seriously but how increasingly it is being seen by banks and insurance houses as a vital part of running an effective and competent business and a prerequisite for their continued support.
This time next week, what will be the Colt’s storyline?
The Colts will need more of this the ground the Ravens
What Cathy Engelbert’s successor owes WNBA players
The players aren’t a problem the next commissioner must solve. They are the answer to unlocking the league's full value.
Folarin Balogun almost fit to make AS Monaco return
Folarin Balogun (25) could be included in AS Monaco’s squad for the game against RC Lens next weekend, as per a report from L’Équipe.Monaco manager Filipe Luís revealed that Balogun had been pla...
England to extend head coach Borthwick's contract
England head coach Steve Borthwick will have his contract extended past the 2028 Six Nations in a bid to avoid uncertainty over his future before and during next year's Rugby World Cup.
Revolut takes aim at business banking with FTSE 250 companies
Fintech’s business division has a target of 1mn customers globally by 2027
UTA health center to hold kickoff for free flu shots Wednesday
The clinic is next to Brazos Park, and appointments are optional but encouraged.
Injuries force local high school to cancel 2 football games
Catholic Central has canceled its next two football games due to injuries.
Dodgers on Deck: Wednesday, September 9 vs. Reds
The Dodgers close out their nine-game homestand on Wednesday night, with one more game against the Cincinnati Reds. Yoshinobu Yamamoto starts Wednesday, and like Tuesday starter Tarik Skubal is set up to face the Reds twice in a row, as these two teams meet up again next week for four games at Great American Ball […]
California’s next governor will face destabilizing surge in uninsured
Should Xavier Becerra cruise to victory in the California governor's race in November, as polling suggests, he will face what may be the steepest decline in health insurance coverage in a...
Michigan Fans Split On Bryce Underwood Ahead Of Oklahoma
Michigan fans are split on Bryce Underwood after the Western Michigan escape, with Oklahoma next. #GoBlue
18 Sports Plays of the Week
ELMIRA, N.Y. (WETM) – It’s time for the next edition of the 18 Sports Plays of the Week. (Video Courtesy: Rochester Aquinas and Wellsboro Hornets Hudl, Chris Wilcox) The 18 Sports team showcases the top plays from the past week in the Twin Tiers. Top honors this week include 5 major moments on the high school […]
Why Brandon Marsh's slump will derail Phillies' NL East chances
The Philadelphia Phillies are looking to surpass the Atlanta Braves in the National League East standings. They will need players to step up over the next few weeks amid their pursuit of winning the division. Of course, Philadelphia is hoping its stars can lead the way. Starting pitching is a strength for this Phillies ball club. Zack Wheeler has […] The post Why Brandon Marsh's slump will derail Phillies' NL East chances appeared first on ClutchPoints.
Central Health to vote on proposed property tax increase for Travis County
Your property taxes could go up again next year. Central Health, which is the hospital district for Travis County, is proposing an increase to provide mental health services to those in crisis.
Midwest Aerial Athletics wins big in Aruba
SIOUX FALLS, S.D. (KELO) —KELOLAND News first took you to Midwest Aerial Athletics back in July. The gym was gearing up to compete on the international stage. “We just competed in Texas, and that was the qualifier for Aruba. So we’re going to Aruba this year and hopefully Australia and then Italy in the next […]
Exclusive | Jimmy Kimmel's late night show set to end after next season after 24 years
Supreme Court rejects Missouri’s request to use congressional map with extra GOP seat
The Supreme Court on Tuesday denied Missouri’s request to use a congressional map for the November midterm election that would have given Republicans a chance to flip a seat, a rare setback for the GOP’s effort to keep control of the House next year by eking out an advantage from its political boundaries.
Local businesses brace for gigantic cargo moves starting next week
Locals anxiously waiting for superloads of heavy equipment — weighing up to 380 tons — to travel through their towns will have to hold on until next week. The first trip, on a giant, specialized truck, is expected to leave a dock in Gilpin’s Schenley section on Monday morning. Officials
2026 North Dakota Behavioral Health & Children and Family Services Conference is next week | Health and Human Services North Dakota
Registration is open for the sixth annual North Dakota Health and Human Services (HHS) Behavioral Health & Children and Family Services Conference, scheduled for Sept. 14-17 in Bismarck. The conference will also be available virtually.
These Companies Made the Inc. Best in Business List. Here’s What Happened Next
Award winners share how they capitalized on the momentum from their Best in Business recognition.
Game Awards Host Geoff Keighley And PlayStation Architect Mark Cerny Will Start Giving $2 Million To Young Game Designers Each Year
The Nova Games Foundation is a new philanthropic initiative aimed at supporting the next generation of game makers
2026 NFL Season Award Predictions: Protector of the Year
The WCG Crew is predicting the 2026 NFL Awards, and next is our pick for Protector of the Year. Could the award stay in Chicago?
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
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AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
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Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
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