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Alexander Isak injury: Liverpool striker feared to have suffered significant damage to lower leg, Sky Sports News understands

Alexander Isak is feared to have suffered a significant lower-leg injury, Sky Sports News understands; Isak scored the opener in the 2-1 win against Tottenham on Saturday but was unable to continue after being caught late by Micky van de Ven

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Dec 21, 2025 • 10:30 AM EST • Sports • skysports.com
Strengthening U.S.-Nigerian Health Cooperation under the America First Global Health Strategy - U.S. Embassy and Consulate in Nigeria

Strengthening U.S.-Nigerian Health Cooperation under the America First Global Health Strategy The United States signed a five-year, $5.1 billion bilateral health cooperation Memorandum of Understanding (MOU) with the Federal Republic of Nigeria December 19 to advance the America First Global Health Strategy, supporting resilient, self-reliant, and durable health systems while promoting accountability and shared responsibility. Under the five-year MOU, the United States intends to commit nearly $2.1 billion in health assistance, with nearly $3.0 billion in new domestic health expenditures by the Government of Nigeria over the same five-year period. This represents the largest co-investment any country has made to date under the America First Global Health Strategy and underscore Nigeria’s commitment to greater national ownership of its health system. Under the MOU, the United States will continue to support surveillance and outbreak response, laboratory systems, health commodities; frontline healthcare workers, and data systems. Nigeria faces significant health challenges, including one of the highest maternal and child mortality rates globally and approximately30 percent of the global malaria burden. U.S. assistance under the MOU will expand access to affordable, preventive and curative services for HIV/AIDS, tuberculosis (TB), malaria, polio, and maternal and child health, strengthening health outcomes across Nigeria. The MOU places a strong emphasis on Christian faith-based healthcare providers, recognizing their indispensable role in delivering care to communities in need. Nigeria’s more than 900 faith-based clinics and hospitals serve more than 30 percent of the country’s 230 million people, often in areas where healthcare facilities are limited or absent. The MOU provides approximately $200 million in dedicated support to strengthen and support these Christian facilities, enhance workforce capacity, and expand access to integrated HIV, TB, malaria, and maternal child health services. Investments in Christian faith-based health institutions are uniquely positioned to complement public-sector facilities and reinforce Nigeria’s overall health infrastructure. The MOU was negotiated in connection with reforms undertaken by the Government of Nigeria to prioritize the protection of Christian populations from extremist violence. As with all U.S. foreign assistance, the President and Secretary of State retain the right to pause or terminate programs that do not align with U.S. national interests, and the United States expects Nigeria to continue making measurable progress in combating religiously motivated violence against Christian communities. This five-year MOU is the latest of several health cooperation MOUs signed in Africa this month. The United States will continue to sign multi-year Bilateral Agreements on Global Health Cooperation with countries receiving U.S. health assistance to advance the America First Global Health Strategy.

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Dec 21, 2025 • 7:49 AM EST • Health • ng.usembassy.gov
German business welcomes pending return of UK to Erasmus Programme

German business has welcomed the United Kingdom's re-entry into the European Union's Erasmus youth education programme from 2027 and hopes that it will lead to an easing of visa requirements. Ulrich Hoppe, head of the German-British Chamber of Commerce (AHK) described the decision as "a very significant step" in remarks made to dpa days after Brussels and London agreed on the step.

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Dec 21, 2025 • 4:25 AM EST • Business • dpa-international.com
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Turning plastic waste into valuable chemicals with single-atom catalysts

The rapid accumulation of plastic waste is currently posing significant risks for both human health and the environment on Earth. A possible solution to this problem would be to recycle plastic waste, ...

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Dec 20, 2025 • 10:00 AM EST • Technology • phys.org
Koch Political Operation Spent Nearly $550 Million During 2024 Cycle

The huge sum shows that while the Koch network may not hold significant power at high levels of the Republican Party, it remains a financial juggernaut.

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Dec 20, 2025 • 5:01 AM EST • Politics • nytimes.com
Blackstone business seeks city relief from streetcar construction impacts

A Blackstone District business owner is asking city officials for financial relief after reporting significant revenue losses during streetcar construction on Farnam Street.

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Dec 19, 2025 • 11:22 PM EST • Business • wowt.com
Health and Health Care for American Indian or Alaska Native People: Key Issues

Due to a combination of lower coverage rates, additional access barriers, and historical and ongoing discrimination, AIAN people continue to face significant disparities in health and health care.

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Dec 19, 2025 • 7:39 PM EST • Health • kff.org
The Ten Most Significant Science Stories of 2025, From Medical Breakthroughs to an Interstellar Visitor

All year long, these moments captivated the public, demonstrated dangerous trends, and pushed research and innovation forward

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Dec 19, 2025 • 12:56 PM EST • Science • smithsonianmag.com
How to Reform Science Funding

Harvard’s recent announcement that it would significantly scale back its doctoral programs came as a shock to the rest of the academic world.

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Dec 19, 2025 • 8:13 AM EST • Science • compactmag.com
Congress leaves for holidays without deal to extend health care subsidies: Here's how it affects you

Monday marked the deadline for Covered California enrollees to select their health plans for 2026, with many waiting until the last minute, hoping for congressional action. But with Congress now on break, those who rely on Affordable Care Act coverage will see premiums climb significantly in the new year.

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Dec 18, 2025 • 10:40 PM EST • Health • abc7news.com
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More photos from Epstein’s estate released by House Democrats as deadline to release DOJ files looms

Democrats on the House Oversight Committee released photos from Jeffrey Epstein’s estate Thursday — the latest in a series of intermittent disclosures that have fueled significant political intrigue in recent weeks about who may have been associated with the convicted sex offender.

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Dec 18, 2025 • 12:00 PM EST • Politics • cnn.com
The Trevor Project Condemns Federal Government Efforts to Restrict Health Care for Transgender Youth

Your Support Saves LGBTQ+Youth's Lives Every DayDonateResearch shows that access to transition-related care is associated with significantly lower rates of […]

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Dec 18, 2025 • 11:25 AM EST • Health • thetrevorproject.org
In a first, a US Navy warship in the Middle East just launched a one-way attack drone

A top US commander called the launch a "significant milestone" in delivering cheap drones to American forces.

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Dec 18, 2025 • 10:44 AM EST • Business • businessinsider.com
What Can U.S. Employers Do About Rising Healthcare Costs?

U.S. employers are grappling with surging healthcare costs as healthcare prices and service volumes rise. Provider consolidation, high drug prices, labor shortages, and growing chronic disease are fueling the cost increases. Employer have largely responded by shifting expenses to workers. Their track record in pursuing aggressive options—including collective purchasing, tiered plans, value-based care, and advocating for changes in government policies—is poor. The big question is whether they have the will to become more aggressive in pursuing remedies. The outlook is not promising. The reasons include the complexity of the problem, employee resistance to some solutions, and the fact that most employers just don’t have sufficient “skin in the game” to take on the disruption and risk that would be required to bend the healthcare cost curve significantly or sustainably.

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Dec 18, 2025 • 8:15 AM EST • Health • hbr.org
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Hospitals acquired by real estate investment trusts associated with greater risk of bankruptcy, closure | Harvard T.H. Chan School of Public Health

REIT acquisition of hospitals had no significant impacts on quality of clinical care or patient outcomes—but had a significant negative impact on hospital finances, according to a new Harvard Chan School study.

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Dec 18, 2025 • 5:30 AM EST • Health • hsph.harvard.edu
Safeguarding Global Health Security in Cameroon through the America First Global Health Strategy - United States Department of State

The United States and the Government of Cameroon signed a bilateral health Memorandum of Understanding (MOU) to expand significant health gains and advance global health security under the landmark America First Global Health Strategy. The MOU puts Americans first by safeguarding our nation from infectious disease threats, while also supporting Cameroon to build robust, self-reliant […]

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Dec 16, 2025 • 5:30 PM EST • Health • state.gov
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Veterinarian and Animal Science Graduate  James F. Dougherty Named to Rutgers Hall of Distinguished Alumni

The Class of 2026 inductees into the Rutgers Hall of Distinguished Alumni have excelled in a varied range of fields—obstetrics and gynecology, addiction prevention and treatment, veterinary medicine, football and entrepreneurship, and government and insurance industry leadership—but they all share a uniquely Scarlet bond: A significant, unwavering devotion to supporting the university where they began […]

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Dec 16, 2025 • 9:40 AM EST • Science • sebsnjaesnews.rutgers.edu
Task force says SF should cull commission system

Voter-approved body recommends significant reforms.

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Dec 15, 2025 • 10:07 PM EST • Politics • sfexaminer.com
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Trump offers ‘platinum’ security guarantees for Ukraine, but US officials caution offer won’t last forever

American officials on Monday described significant progress in talks to bring Russia’s war in Ukraine to an end, suggesting beefed-up security guarantees for Kyiv had advanced the peace talks — but that the US offer would not be on the table forever.

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Dec 15, 2025 • 12:43 PM EST • Politics • cnn.com
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Tencent Music Entertainment Group's (NYSE:TME) largest shareholders are public companies with 61% ownership, institutions own 28%

Key Insights Significant control over Tencent Music Entertainment Group by public companies implies that the general...

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Dec 15, 2025 • 5:08 AM EST • Entertainment • finance.yahoo.com
Why heart disease is so often undiagnosed in women

As a cardiologist, I see this far too often: women come to us later in the course of heart disease, sometimes after weeks or even months of vague symptoms that were dismissed or misdiagnosed. We’ve made significant advances in cardiology, but one thing hasn’t changed enough: Heart disease in women still flies under the radar. That’s something I’m passionate about changing.

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Dec 15, 2025 • 4:00 AM EST • Health • uknow.uky.edu
Two-thirds of Americans say government should ensure health care for all: poll

The poll comes as more than 22 million Americans brace for significantly higher health care costs next year.

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Dec 14, 2025 • 4:11 PM EST • Health • fox6now.com
Two-thirds of Americans say government should ensure health care for all: poll

The poll comes as more than 22 million Americans brace for significantly higher health care costs next year.

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Dec 14, 2025 • 4:11 PM EST • Health • fox13news.com
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Nutrient deficiency linked to heart disease risk for millions, new study warns

Global omega-3 deficiency affects 76% of people worldwide, significantly increasing risks for heart disease, cognitive decline and chronic inflammation.

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Dec 14, 2025 • 11:51 AM EST • Health • foxnews.com
Health insurance under Affordable Care Act to skyrocket after Senate fails to extend tax credits

Health care advocates and progressive groups across Florida said the U.S. Senate's failure to extend premium subsidies for the Affordable Care Act was a "disheartening setback" that will significantly raise the cost of health insurance for nearly 5 million Floridians, including hundreds of thousands of people in South Florida.

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Dec 14, 2025 • 8:14 AM EST • Health • wusf.org
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BMW crashes into Santa Monica business, leaving driver seriously injured

A vehicle crashed into a building in Santa Monica late Thursday night, causing significant damage to the structure and sending the driver to the hospital.

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Dec 12, 2025 • 9:39 AM EST • Business • foxla.com
Why Indiana is such a major unforced error for Trump

The Indiana state Senate’s rejection of President Donald Trump’s redistricting push is one of the most significant GOP rebukes of Trump to date, and at a particularly inauspicious time for him.

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Dec 12, 2025 • 4:00 AM EST • Politics • cnn.com
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Michael Jordan was already a basketball legend. Now, he’s one in NASCAR too

Thursday's settlement was that significant for NASCAR's teams that Jordan just made himself a transformative figure in yet another sport.

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Dec 11, 2025 • 7:37 PM EST • Sports • nytimes.com
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AI Bubble Or Business Revolution? Essential Business Insights

Most AI companies will fail, yet the industry will transform business. The trial and error economy drives today's AI revolution alongside significant risks.

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Dec 11, 2025 • 4:57 PM EST • Business • forbes.com
Einstein was right: Time ticks faster on Mars, posing new challenges for future missions

Clocks on Mars tick faster by about 477 microseconds each Earth day, a new study suggests. This difference is significantly more than that for our moon, posing potential challenges for future crewed missions.

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Dec 11, 2025 • 12:50 PM EST • Science • livescience.com
Man Utd financial results: Cost-cutting having an impact in first quarter numbers for new financial year

Redundancies and other cost-cutting measures at Man Utd have been reflected in their latest quarterly financial results; there have been small losses that will not be significant for a business of their size; the results will also not affect their plans for the January transfer window

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Dec 11, 2025 • 9:00 AM EST • Sports • skysports.com
Maker’s Mark nets first sports league sponsorship with Unrivaled

The bourbon brand will have a significant presence around the women's basketball league both on-premise and digitally.

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Dec 11, 2025 • 4:31 AM EST • Sports • marketingdive.com
Is the universe ending sooner than we thought? New physics suggests a much shorter lifespan | - The Times of India

Science News: A groundbreaking study from Radboud University suggests the universe may end in approximately 10^78 years, significantly earlier than the previously assumed 10^1100 years. By revisiting Hawking radiation, researchers argue that all compact massive objects will evaporate, altering our understanding of cosmic lifespans.

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Dec 11, 2025 • 3:54 AM EST • Science • timesofindia.indiatimes.com
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The New WHO Pandemic Treaty and Global Health Governance: Incorporating Common but Differentiated Responsibilities into PABS  - Georgetown Journal of International Affairs

On May 20, 2025, the World Health Assembly unanimously adopted the World Health Organization (WHO) Pandemic Agreement, an international treaty designed to strengthen pandemic prevention, preparedness, and response. The product of three years of arduous negotiations, the treaty marks a new era of global cooperation in public health. However, core aspects of the agreement remain unresolved—notably the Pathogen Access and Benefit-Sharing (PABS) System, which is intended to ensure equitable access to pandemic-related materials and benefits. To support the successful implementation of the WHO Pandemic Agreement, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Introduction For the first time, an international treaty has enshrined the principle of “One Health,” the compelling idea that the health of animals, humans, and the environment all contribute to pandemic risks. SARS (2003), H1N1 (2009–10), Ebola (2014–16), and COVID-19 all emerged through zoonotic spillover from animal hosts—respectively, civets, hogs, and bats. Together, they underscore the need for a coordinated, cross-sectoral approach. The Pandemic Agreement responds to this call, requiring state parties to acknowledge the ecological interplay and commit to a comprehensive “One Health” strategy. Specifically, Article 5 charges governments to address “the drivers of pandemics and the emergence and re-emergence of infectious disease at the human-animal-environment interface,” including wild animal markets, deforestation, and antibiotic overuse. Yet the effectiveness of this “One Health” vision depends equally on the free flow of scientific information and data among countries and institutions. Just as environmental and animal health factors have been neglected in past global frameworks, so too has data sharing been marginalized, despite its centrality to timely detection and response. The Pandemic Agreement takes an important step by requiring governments to enhance data collection and cooperate with the World Health Organization (WHO). However, these provisions will remain aspirational without a robust Pathogen Access and Benefit-Sharing (PABS) annex. The PABS system will determine whether countries and researchers can rapidly exchange pathogen samples and genetic data while ensuring equitable access to resulting research and development, including diagnostics, therapeutics, and vaccines. Without such mechanisms, the treaty’s promise to operationalize “One Health” and strengthen global preparedness will risk becoming largely symbolic, echoing earlier failures to translate shared principles into coordinated action. Equity Concerns When the 2025 Health Assembly adopted the Pandemic Agreement, it left the difficult question of access to pathogens and the sharing of resulting benefits to be addressed in a separate agreement. Negotiations on this separate agreement, PABS, are now underway in Geneva. Yet governments remain divided over fundamental questions of equity between the countries that primarily contribute to the system and those that primarily draw from it—and consequently benefit. For example, wildlife in countries bordering the equator is likely to produce PABS materials, but companies in Europe are likely to use them to develop lucrative products. The most likely contributor countries are likely to be those biodiverse countries around the equator, such as Brazil, the Democratic Republic of the Congo, and Indonesia, where the number of human-mammalian viral host interactions is large. Conversely, countries most likely to benefit from this material are those with the technology, investors, and infrastructure to capitalize on genomic data, such as the United States, EU member states, and Japan. This imbalance reflects a broader pattern seen in prior international frameworks. Now, as in the past, the wealthiest countries in the world (a useful heuristic is membership of the Organisation for Economic Co-operation and Development (OECD)) disproportionately benefit from systems in which pathogens and genomic sequencing data are contributed to a common source. Under the International Agreement on Plant Genetic Resources for Food and Agriculture (the “Plant Treaty” or “Seed Treaty”) and the Pandemic Influenza Preparedness (PIP) Framework, companies from Europe and North America disproportionately withdraw biological samples and data for development into lucrative medical products. Their governments and companies have both statutory and contractual claims to the products that those companies correspondingly produce. PABS appears poised to follow the same pattern. The text calls for strong language on access to pathogens and associated data, but the corresponding benefits that should flow to poorer countries are couched in equivocal or non-binding language. Common but Differentiated Responsibilities To address these inequities, the principle of “common but differentiated responsibilities” should be formally incorporated into the negotiating agenda of the PABS annex. Common but differentiated responsibilities are often a feature of climate change negotiations. The basic principle is that, even though all countries should reduce carbon emissions, governments that became rich and powerful through massive carbon emissions (e.g., France, the United Kingdom, the United States) should have a greater obligation to address the resulting crises. Applied to PABS, it would require that governments hosting and supporting companies developing lucrative products carry greater obligations toward the cost of running the PABS system; share benefits or final medical products; and transfer technology to help countries worldwide develop their own capacities to innovate and manufacture vaccines during an emergency. For example, an annex could mandate that any company based in an OECD country that withdraws PABS material would be obligated to donate the resulting diagnostics, therapeutics, or vaccines to the WHO during a public health emergency or pandemic. Questions remain about how robust those donations would be, but the principle is that they should deliver highly significant lifesaving benefits to be equitably shared. Theoretically, this approach mirrors the PIP Framework, in which companies withdrawing influenza samples are required to pay half of the operating costs. In practice, however, the framework has fallen short. The PIP Framework Secretariat has struggled to secure payments from companies, with companies often disagreeing over how much is owed. Additionally, without another pandemic influenza to test the strength of the agreement during a public health emergency, corporate compliance with sharing mechanisms remains unknown. Even if these limitations did not characterize the PIP Framework, partially paying for operating expenses does not address the inequity in access to genetic data and pathogen samples that left less developed countries last in line for COVID-19 vaccines (and, before them, H1N1). Common but differentiated responsibilities would go further, addressing governments’ legitimate grievances regarding information sharing. It would make withdrawals of PABS material and resulting products more transparent, building trust across the board. Enforcement and Enduring Success A key implication of this approach is that the governing mechanism of the PABS must have real enforcement authority. The WHO Pandemic Agreement delegates its core governance responsibilities to a Conference of the Parties (COP)—a governing body composed of one representative from each participating government, similar to those established under the UN Framework Convention on Climate Change and the WHO Framework Convention on Tobacco Control. The proposed WHO Pandemic Agreement COP is charged with oversight functions but ultimately possesses no real authority to compel a government to take any action it does not wish to take. The text does not give the COP the ability to, for example, sanction a party that does not comply with either textual obligations or PABS provisions. In other words, there are no effective mechanisms in place to ensure compliance. Perhaps just as significant, establishing a meaningful enforcement mechanism within the PABS system would strengthen the WHO’s credibility and its ability to ensure compliance across global health governance. By setting a precedent for accountability, such a mechanism could enhance the organization’s authority not only within the Pandemic Agreement but also in enforcing the revised International Health Regulations and other frameworks for public health emergencies. Conclusion The PABS annex can—and should—be different. It should establish clear responsibilities for funding as well as for sharing the diagnostics, therapeutics, and vaccines that result from contributions to the system. The system, in turn, must include a dedicated body empowered to hold governments and the corporations they sponsor accountable for their responsibilities before, during, and after pandemics. Doing so would restore trust in the broader agreement, which was eroded as commitments were repeatedly diluted while parties scrambled to meet their own self-imposed deadlines during the Pandemic Agreement negotiations. A robust PABS Annex would cement a grand social bargain. Wealthier countries and their corporations would gain unimpeded access to scientific information essential for developing and manufacturing lifesaving medical products. As such, they would stand to gain considerable economic benefit. Yet that privilege must be matched with responsibility. The grand bargain must include not only the right to innovate, but also the duty to ensure that innovation serves all. As medical products are developed and produced through collective contributions, every person must have equal access. All human beings deserve an equitable chance to survive—to save their own life, the lives of their families, and the well-being of their communities. … Sam Halabi, JD, MPhil, is the Bette Jacobs Endowed Professor at Georgetown University’s School of Health and the Director of the Center for Transformational Health Law at Georgetown Law. He serves as the co-lead for the WHO’s Working Group on Regulatory Consideration on AI and Health’s training workstream. He earned his JD from Harvard, his MPhil from Oxford, and undergraduate degrees from Kansas State University. Lawrence Gostin, LLD (Hon.), JD, BA, is University Distinguished Professor and Founding Director and Timothy and Linda O’Neill Professor of the O’Neill Institute for National and Global Health Law. He is the author of Global Health Security: A Blueprint for the Future (Harvard University Press, 2021); Global Health Law (Harvard University Press, 2014); Public Health Law: Power, Duty, Restraint (University of California Press, 3rd ed., 2016); Public Health Law and Ethics: A Reader (University of California Press, 3rd ed., 2018); Law and the Health System (Foundation Press, 2014); Principles of Mental Health Law & Practice (Oxford University Press, 2010). He also directs the WHO Collaborating Center at Georgetown University. Image Credit: United States Mission Geneva, CC BY 2.0, via Wikimedia Commons

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Dec 11, 2025 • 12:00 AM EST • Health • gjia.georgetown.edu
Federal health policy changes could upend coverage across U.S., experts warn | Harvard T.H. Chan School of Public Health

Significant changes in federal policy slated to take effect in the coming months could disrupt health care coverage, costs, and access to care for millions of people, according to experts who spoke at a Studio event at Harvard Chan School.

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Dec 10, 2025 • 4:11 PM EST • Health • hsph.harvard.edu
MacKenzie Scott donated $7.1 billion to nonprofits in 2025, a major increase

The author and philanthropist MacKenzie Scott revealed $7.1 billion in donations to nonprofits in 2025 Tuesday, marking a significant increase in her annual giving from recent years.

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Dec 10, 2025 • 12:05 AM EST • Business • cnn.com
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Prairie strips can rapidly improve soil health

Prairie strips can improve measures of soil health faster than expected, according to new research by Iowa State University scientists working in cooperation with the Soil Health Institute. Earlier studies have shown that prairie strips established in approximately 10% of a field can significantly increase biodiversity and pollinator habitat, reduce erosion and improve water quality. However, strips’ impacts on soil health have remained largely unexamined until now. Findings published recently in the Journal of Soil and Water Conservation showed that prairie strips improved a number of soil health measures within 10-12 years.

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Dec 9, 2025 • 2:40 PM EST • Health • cals.iastate.edu
New studies show that AI can influence voters more than campaign ads

AI chatbots can significantly influence voters' political opinions, two studies find.

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Dec 9, 2025 • 12:27 PM EST • Politics • sfgate.com
Barnes aims to raise $50M for governor campaign, says big money in politics is a concern

Democratic gubernatorial candidate Mandela Barnes says he’s shooting to raise “closer to $50 million” for his campaign cycle, which would be a significant uptick from his 2022 bid for U.S. Senate.

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Dec 9, 2025 • 11:45 AM EST • Politics • wispolitics.com
Google unveils plans to try again with smart glasses in 2026

It is a significant turnaround for the tech giant after its first attempt - Google Glass - was pulled in 2015.

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Dec 9, 2025 • 11:34 AM EST • Technology • bbc.com
A Trump-backed candidate faces a Democrat with national support in Miami's mayoral race. Here's what to know

Big-name Republicans and Democrats have joined the campaign trail, making this a significant test for both parties.

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Dec 9, 2025 • 10:58 AM EST • Politics • pbs.org
A New Chapter in Hormone Health: Dr. Rachel Fishman Oiknine Brings MDVIP's Personalized Model to St. Louis

Women in the St. Louis region will soon have access to a new model of personalized endocrinology care centered on women's health and long-term wellness. The new MDVIP-affiliated practice, led by Rachel Fishman Oiknine, MD, MSCP, marks a significant expansion of specialty care within the MDVIP network.

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Dec 8, 2025 • 8:37 AM EST • Health • finance.yahoo.com
Penn State Health introduces advanced MRI technology that reduces anesthesia time

Penn State Health is now using a cutting-edge imaging technology that significantly reduces the time patients spend under anesthesia during MRI scans – with especially meaningful benefits for children.

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Dec 8, 2025 • 8:15 AM EST • Health • pennstatehealthnews.org
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Wave Life Sciences Announces Positive Interim Data from Phase 1 INLIGHT Trial of WVE-007 (INHBE) for Obesity; Single Dose Resulted in Improvement in Body Composition With Fat Loss Similar to GLP-1 at Three Months Without Muscle Loss

Following a single subcutaneous 240 mg dose, WVE-007 (INHBE GalNAc-siRNA) improved body composition at three months compared to baseline, with a 9.4% reduction in visceral fat (p=0.02), a 4.5% reduction in total body fat (3.5 lbs; p=0.07), and a 3.2% increase in lean mass (4.0 lbs; p=0.01), with no statistically significant changes in the placebo group Sustained and robust suppression of serum Activin E supports expectations for continued improvements in body composition, further fat loss, and p

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Dec 8, 2025 • 7:30 AM EST • Science • finance.yahoo.com
Prairie Business releases 2025 40 Under 40 list

The inspiring and dedicated professionals listed every year come from a wide range of industries and have made significant impacts in their chosen professions and communities.

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Dec 7, 2025 • 8:57 AM EST • Business • inforum.com
Institutional investors own a significant stake of 40% in Seaport Entertainment Group Inc. (NYSE:SEG)

Key Insights Institutions' substantial holdings in Seaport Entertainment Group implies that they have significant...

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Dec 7, 2025 • 8:10 AM EST • Entertainment • finance.yahoo.com
Analysis: Trump’s retribution campaign is going poorly — and could backfire

President Donald Trump’s retribution campaign has long suffered from a very significant and important deficit — and that’s the actual evidence.

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Dec 5, 2025 • 2:06 PM EST • Politics • cnn.com
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Eurovision has faced political boycotts before – how does the latest compare?

Decision by four countries to pull out over Israel’s inclusion is significant for the contest but crisis may not be existential

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Dec 5, 2025 • 10:52 AM EST • Politics • theguardian.com
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Congratulations to 2025’s Prairie Business 40 Under 40 honorees!

This year’s 40 Under 40 honorees are exceptional professionals from many industries and sectors who are making significant impacts within their organizations and communities. They are industry executives, administrators, community leaders, entrepreneurs and more. These high-caliber individuals are making their mark in their companies and sectors.

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Dec 5, 2025 • 9:00 AM EST • Business • grandforksherald.com
Pediatrician and Geneticist to Receive 2026 Trinity College President’s Medal for Science and Innovation

Pediatrician and geneticist D. Holmes Morton, M.D., IDP’79, H’90 will receive the 2026 Trinity College President’s Medal for Science and Innovation, which recognizes individuals who have made significant contributions to the STEM fields.

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Dec 4, 2025 • 7:00 PM EST • Science • trincoll.edu
SmartMarket Solutions Awarded FBA's 2025 Business Opportunity of the Year

SmartMarket Solutions is proud to announce that the company has been awarded 1st Place for Business Opportunity of the Year at the 2025 Franchise Brokers Association (FBA) Award Ceremony. This recognition is especially significant as 2025 marks the company's inaugural year in the FBA inventory.

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Dec 4, 2025 • 4:08 PM EST • Business • finance.yahoo.com
Millennium suffered big losses in one of the $81 billion hedge fund's favorite strategies last month

Teams run by big-name portfolio managers such as Glen Scheinberg and Pratik Madhvani suffered significant losses in November.

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Dec 4, 2025 • 3:34 PM EST • Business • businessinsider.com
"In a lot of situations, it's straight up double" - Path of Exile 2 is about to get a significant performance boost, especially on PS5 and Xbox S/X

Action role-playing game Path of Exile 2 is about to get a significant performance boost on all platforms - one that, a…

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Dec 4, 2025 • 2:30 PM EST • Technology • eurogamer.net
Trucking credit metrics at BMO slide as the business gets smaller

The 4Q credit metrics in BMO’s transportation sector, a major lender to trucking, were significantly worse in many areas. The post Trucking credit metrics at BMO slide as the business gets smaller appeared first on FreightWaves.

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Dec 4, 2025 • 7:53 AM EST • Business • finance.yahoo.com
Mental health conditions may heighten liver cancer risk in veterans due to increased hepatitis C, UCLA study finds

A new study led by UCLA Health investigators found that mental health conditions, especially alcohol use disorder and PTSD, significantly increase the likelihood of developing liver cancer among Veterans living with cirrhosis of any etiology.

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Dec 3, 2025 • 10:21 AM EST • Health • uclahealth.org
Marquee Sports Network has made some staff cuts

The Cubs flagship channel has made some significant changes.

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Dec 3, 2025 • 10:00 AM EST • Sports • bleedcubbieblue.com
Idaho sheriffs worry Medicaid mental health cuts pose ‘significant public-safety concern’

The Idaho Sheriffs' Association warned elected officials of public safety risks from cuts to Medicaid mental illness services.

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Dec 3, 2025 • 6:01 AM EST • Health • idahocapitalsun.com
Yuyu Pharma Announces Strategic Investment in Dalan Animal Health as Part of Accelerated Global Expansion in Animal Health

Yuyu Pharma announced today that it has completed a strategic investment in Dalan Animal Health, a U.S.-based biotechnology company advancing an innate immunity–based platform for developing vaccines for honeybees and shrimp. The investment marks a significant step in Yuyu Pharma's plan to become a more active global player in the fast-growing animal health sector.

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Dec 2, 2025 • 9:00 AM EST • Health • finance.yahoo.com
Police raid mail-order drugs business in Greater Manchester

Greater Manchester Police said the mail-order drugs business has opened up significantly.

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Dec 2, 2025 • 8:28 AM EST • Business • bbc.com
Vaccine Committee May Make Significant Changes to Childhood Schedule

Comments by President Trump, Health Secretary Robert F. Kennedy Jr. and some panelists suggest the committee is likely to delay hepatitis B shots and discuss revising the use of other vaccines.

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Dec 2, 2025 • 5:04 AM EST • Health • nytimes.com
Cubs' Marquee Sports Network eliminates GM position among cuts

The network significantly reduced its digital-content team, including cutting director of content Tony Andracki and reporter Andy Martinez.

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Dec 1, 2025 • 9:01 PM EST • Sports • chicago.suntimes.com
Deep dive
😐 Neutral (-1%)
wow
57%
ahah
43%
Small Business Saturday rescheduled after snow disrupts shopping event

MADISON, Wis. -- Small Business Saturday faced significant disruption due to snow, but local businesses and advocates remain optimistic about a rescheduled event planned for this upcoming weekend.

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Dec 1, 2025 • 5:11 PM EST • Business • channel3000.com
Deep dive
😐 Neutral (7%)
wow
67%
ahah
33%
Why Your Company Needs a Chief Data, Analytics, and AI Officer

Who should be in charge of data, analytics, and AI? While there are many possible divisions of responsibility and reporting structures, a combined role—the CDAIO (Chief Data, Analytics, and AI Officer)—will best prepare organizations as they plan for AI going forward. To succeed, this role needs a clear mandate that includes owning AI strategy, preparing for a new class of risks, developing the AI tech stack, ensuring the company’s data is ready for AI, creating an AI ready culture, developing talent and partnerships, and generating significant ROI on AI investments. Given the emphasis on business value creation, in most cases CDAIOs should be positioned closer to business functions than to technology operations.

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Dec 1, 2025 • 8:15 AM EST • Business • hbr.org
Brouk plans to focus on Black maternal health in the coming legislative session

New York State has made significant advancements towards supporting Black maternal health, but state leaders say there’s still more work to be done.

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Dec 1, 2025 • 5:20 AM EST • Health • wxxinews.org
Apple Reportedly to Launch New Studio Display in 2026 with A19 Pro and Mini LED Upgrades - VOCO News | Global Chinese Instant News Network

Apple's Studio Display is rumored to receive a major upgrade in 2026, with the A19 Pro chip and Mini LED panel being the biggest highlights. The new generation display is expected to significantly improve Apple's long-standing limitations with high refresh rate external displays.

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Dec 1, 2025 • 5:16 AM EST • Technology • news.vocofm.com
5 morning habits that reduce cancer risk and promote long-term health | - The Times of India

Your morning routine significantly impacts long-term health and cancer risk. Simple daily habits like morning exercise, a plant-based breakfast, sunli

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Dec 1, 2025 • 1:00 AM EST • Health • timesofindia.indiatimes.com
Can fibre improve heart health naturally? Cardiologist reveals how it lowers cholesterol and protects your arteries | - The Times of India

Beyond gut health, fibre significantly bolsters your heart. Cardiologist Dr. Dmitry Yaranov reveals it lowers bad cholesterol, stabilizes blood pressu

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Nov 30, 2025 • 9:30 PM EST • Health • timesofindia.indiatimes.com
Using network science to evaluate landslide hazards on Big Sur Coast, California, USA

Abstract. Landslides, ranging from slips to catastrophic failures, pose significant challenges for prediction. This study employs a physically inspired framework to assess landslide hazard at a regional scale (Big Sur Coast, California). Our approach integrates techniques from the study of complex systems with multivariate statistical analysis to identify areas prone to landslide hazards. We successfully apply a technique originally developed on the 2017 Mud Creek landslide and refine our statistical metrics to characterize landslide hazard within a larger geographical area. Our method is compared against factors such as landslide location, slope, displacement, precipitation, and InSAR coherence using multivariate statistical analysis. Our network analyses, which incorporates spatiotemporal dynamics, perform better as a monitoring technique than traditional methods. This approach has potential for real-time monitoring and evaluating landslide hazard across multiple sites.

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Nov 30, 2025 • 7:00 PM EST • Science • nhess.copernicus.org
The Glass Wall: Google’s Enterprise Protocols Are Erasing the Line Between Personal Texts and Corporate Oversight

Google’s latest Workspace updates grant employers new powers to archive and audit text messages on managed Android devices. This shift, driven by SEC compliance and data loss prevention needs, challenges the BYOD model and raises significant privacy concerns, forcing a reevaluation of the boundary between personal privacy and corporate security.

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Nov 30, 2025 • 10:10 AM EST • Technology • webpronews.com
Scientists find a hidden obesity trigger in soybean oil

Researchers at UC Riverside have uncovered why soybean oil, one of America's most widely consumed ingredients, drives significant weight gain—at least in mice. The findings point not to the oil itself but to the fat-derived molecules it produces inside the body, called oxylipins, which can trigger inflammation, alter liver function, and influence genes tied to metabolism.

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Nov 30, 2025 • 7:00 AM EST • Science • sciencedaily.com
UK Tax Clarity Alleviates Significant Uncertainty for Flutter Entertainment

Flutter Entertainment (NYSE:FLUT) is one of the best upside stocks to buy now. On November 28, Citi analyst Ben Shelley lowered the firm’s price target on Flutter Entertainment to $320 from $340 with a Buy rating on the shares. This sentiment was announced as Citi stated that the uncertainty surrounding a potential UK tax increase […]

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Nov 30, 2025 • 12:26 AM EST • Entertainment • finance.yahoo.com