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2026-2027 Audree V. Fowler Fellows in Protein Science
Graduate students Lenka Milojević (Zhou group), Akshaya Narayanasamy (Lindert group), Sarah Singleton (Conway group), and Janet Zhong (Feigon group) have been selected as 2026–27 Fowler Fellows and shared their research at a special event on Oct. 13, 2026. 2026-27 Fowler Fellows – Sarah Singleton, Lenka Milojević, Janet Zhong, and Akshaya Narayanasamy. Akshaya Narayanasamy and Prof. Steffen Lindert. Sarah Singleton and Prof. Stuart Conway. Janet Zhong and Prof. Juli Feigon. About the 2026-27 Audree Fowler Fellows in Protein Science Lenka Milojević is a fifth-year Biophysics Ph.D. candidate in the lab of Professor Z. Hong Zhou at UCLA. As an undergraduate at Maastricht University, she studied the structural basis of Mycobacterium tuberculosis virulence and amyloid-β fibril nucleation in the lab of Professor Peter Peters. She completed her bachelor’s thesis research at UCLA in the lab of Professor David Eisenberg, focusing on amyloid disaggregation, before beginning her doctoral studies. In the Zhou lab, Lenka uses cryo-electron tomography to visualize and characterize membrane-associated protein assemblies across a range of viral and cellular systems. Akshaya Narayanasamy is a fifth-year Ph.D. student in the Department of Chemistry and Biochemistry at UCLA, mentored by Professor Steffen Lindert. She earned her B.S.-M.S. in Chemistry from the Indian Institute of Science Education and Research, Thiruvananthapuram, where she worked in Professor Mahesh Hariharan’s lab investigating how single-atom substitutions influence crystal packing and charge transport behavior. She received her M.S. in Physical Chemistry from The Ohio State University before moving with the Lindert lab to UCLA. At UCLA, Akshaya develops integrative modeling methods that combine deep learning and Rosetta with experimental data, such as ion mobility mass spectrometry and cryo-EM, to improve protein structure prediction. Her current work focuses on developing an experimentally guided diffusion model and designing de novo protein binders with potential antibacterial activity. Ultimately, she aims to bridge AI-based structure prediction and experimental data to make computational protein models more reliable for drug discovery and therapeutic design. Sarah Singleton is a 4th year BMSB student, working in Professor Stuart Conway’s lab. She earned her B.S. in Biochemistry at Simmon University (Fenway, MA). Her research is centered on drugging the previously undruggable class of proteins—transcription factors. Zinc finger (ZF)-containing transcription factor proteins typically contain multiple ZF motifs, but little is known about the principles that govern the recognition of multi-ZF arrays by immunomodulatory imide drugs (IMiDs). In a multi-ZF array that contains several potentially targetable ZFs, which will be accessible and why? How does the surrounding protein architecture inform IMiD recognition? Sarah’s research aims to utilize her findings on the fundamental principles of ZF recognition to design IMiD therapeutics for transcription factors involved in health and disease. Janet Zhong is a fourth-year BMSB student, working in Professor Juli Feigon’s laboratory. She received her BSc and MRes from Imperial College London. At UCLA, Janet combines cryo-electron microscopy (cryo-EM) and biochemical approaches to investigate how proteins and RNAs assemble into ribonucleoprotein structures. Her research focuses on telomerase, the enzyme that maintains chromosome ends, with interests in its structure, assembly, and mechanisms. She has also worked on capturing the cryo-EM structure of a small bacterial non-coding RNA called raiA motif RNA. About Dr. Audree Fowler A strong supporter of the basic sciences and medicine at UCLA, alumna Dr. Audree Fowler (B.S. ’56 chemistry, Ph.D. ’63 biochemistry) established the Audree V. Fowler Fellows in Protein Science in 2008. Fowler was Director UCLA Protein Microsequencing Facility from 1984-1999 and is a Researcher Emeritus of the UCLA Department of Biological Chemistry. She is one of the first four women to receive a Ph.D. from the UCLA Department of Chemistry & Biochemistry. In 2018, the women were awarded the department’s 2018 Alumni Legacy Awards in recognition of their achievements in life, and generous support and service to UCLA. “The sciences gave me a great life. Now I want to help others have access to the same opportunities I enjoyed,” Fowler explained when she established the Fowler Fellowships endowment. Applications for the fellowships are solicited from graduate students in the Molecular Biology Interdepartmental (MBI) Ph.D. Program, Biological Chemistry, and Chemistry & Biochemistry Departments. In addition to presenting their research at a special seminar, the recipients each receive a $5,000 award. Previous Fowler Fellows from the UCLA Department of Chemistry & Biochemistry 2025-26 – Nikki Cheung (Clubb Group), Jonathan Jih (Zhou Group), Eileen Olivares (Loo Group), and Lily Taylor (Rodriguez Group) 2024-25 – Andrew Goring (Clubb lab), Eric Pang (S. Clarke and Rodriguez labs), and Miranda Villanueva (Backus lab) 2023-24 – Alexandra Turmon (Backus lab), Cindy Wang (S. Clarke and C. Clarke labs) 2022-23 – Cody Gillman (Gonen lab), Declan Evans (Houk lab), Troy Lowe (S. Clarke lab), Ashley Julio (Backus lab), and Alex Stevens (Hong Zhou lab) 2021-22 – Weixian Deng (Wohlschlegel/Plath labs), Yi Xiao “Sean” Jiang (Eisenberg lab), Maria Flores (Rodriguez lab), Carter Lantz (Loo lab), and Logan Richards (Rodriguez lab). 2020-21 – Janine Fu (Loo lab), Calina Glynn (Rodriguez lab), and Jiahui Lu (Eisenberg lab) 2019-20 – David Boyer (Eisenberg lab), Orlando Martinez (Clubb lab) and John Muroski (Loo lab) 2018-19 – Scott McConnell (Clubb lab), Kevin Murray (Eisenberg lab), Rebeccah Warmack (S. Clarke lab) 2017-18 – Michael Hughes (Eisenberg lab), Yuxi Liu (Yeates lab), Kanishk Jain (S. Clarke lab) 2016-17 – Brendan Amer (Clubb Lab) and Jeff Vinokur (Bowie Lab) 2015-16 – Henry Chan (Feigon lab), Smriti Sangwan (Eisenberg lab), Nicholas Woodall (Bowie lab) 2014-15 – Dan McNamara (Yeates lab) 2013-14 – Alex Jacobitz (Clubb lab), Alexander Patananan (S. Clarke lab), Carly Ferguson (Loo lab) 2012-13 – Letian Xie (C. Clarke lab), Anni Zhao (Eisenberg lab) 2011-12 – Timothy Anderson (Clubb lab), Soohong Kim (Weiss lab) 2010-11 – Zeynep Durer (Reiser lab), Cecilia Zurita-Lopez (S. Clarke lab) 2009-10 – Luki Goldschmidt (Eisenberg lab), Kristofer Webb (S. Clarke lab), Sheng Yin (Loo lab) 2008-09 – Nathan Joh (Bowie lab), Neil King (Yeates lab) Photos courtesy of Helen Houldsworth, the Molecular Biology Institute.
ALE Investigating Business Located at State House Candidate's Property
Officials received a complaint about a video gambling business located at GOP candidate Charles Taylor’s Lee County rental property.
Chornobyl's Genetically Unique Dogs Are Likely The Result Of Natural Selection, Not Radiation-Scrambled DNA
Wild dogs living near the remnants of the Chornobyl nuclear plant are genetically distinct, but the reason is a little more subtle than you might think.
GOP gambles on cruelty as a campaign strategy
As Donald Trump’s brand of politics is normalized across the GOP, not everyone is reaping the same benefits
Michigan State's Exhibition Losses: Good or Bad?
Early stumbles against UConn and Marquette have Spartan fans on edge. Discover how Tom Izzo’s grueling schedule turns exhibition adversity into a strategic blueprint for Big Ten dominance.
Indiana basketball adding court sponsor at Assembly Hall
Indiana basketball is partnering with Lilly for a "significant" multiyear court advertising partnership.
Ohio Casino Control raids business in Highland County in illegal gambling probe
Dozens of illegal slot machines were seized during an illegal gambling probe at a business in Highland County, according to the Ohio Casino Control Commission.
Three Things Florida Must do to Defeat Georgia in Week 9
From forcing fumbles to unleashing Jadan Baugh, the Gators must execute a precise blueprint to topple the Bulldogs.
Danish students more likely to gamble for entertainment following classroom presentations
A survey of almost 2,000 students found greater awareness of gambling mechanics after presentations by the Danish Gambling Authority.
Candidates are giving lowkey instructions on how to attack their opponents. Here’s how it works
Two legislative campaigns deleted their suspected red boxes after CalMatters asked questions about them for this story
The 5 Scariest Uses of AI in N.C. Politics This Election
Now anyone can create campaign materials with the help of artificial intelligence. That doesn’t mean they should.
I’m a gen Z voter. Content creators have far less power than politicians think
Both US parties scramble to win young voters via influencer operations. The evidence doesn’t support their efforts
FDA, CMS scramble to avoid regulatory logjam as more states look to test AI in clinical settings
Officials are moving behind the scenes to head off a conflict brewing between states and the federal government over regulating AI.
Anthropic Is a Revolutionary Business, but Its IPO Is Still an Enormous Gamble
The artificial-intelligence trade is full of competitors like OpenAI, Google, and various open-weight models, which makes backing Anthropic risky.
Ventura County students host community candidate forum ahead of midterms
Santa Paula High School students questioned local candidates for city council, school board of trustees, and California State Assembly
Packers vs. Carolina Panthers, Week 8 open thread
Join us at Buffalo Rumblings to chat LIVE during Green Bay Packers vs. Carolina Panthers for Week 8 of Thursday Night Football
NC House candidate sues political group, saying it made false claims about him
North Carolina House candidate Charles Taylor is suing the Sandhills Citizens Alliance over campaign mailers. He alleges the political group made false claims about his involvement with a purported gambling operation in Lee County.
Chip Kelly's old-school gamble, Northwestern's new-school vision have Wildcats dreaming of the College Football Playoff
Ashley Graham says fundraising for her new wine brand was 'humbling'
Speaking at Business Insider's The Long Play, Ashley Graham shared how she has built an impactful, lasting brand beyond modeling.
Election 2026: Key races and issues facing western North Carolina voters
WLOS News 13 assembled a panel of experts with a range of experience in politics to discuss discuss races and issues facing WNC voters.
Inside the scramble that moved Thursday's WNBA Finals game to 12:30 p.m. ET
Many different options were considered before the WNBA decided to move Thursday's Game 6 of the WNBA Finals to a midday time slot.
DraftKings CEO on talking to your kids about sports gambling
DraftKings CEO Jason Robins tells CNBC’s Contessa Brewer that parents should talk to their kids about gambling addiction and that he’s tackled the subject with his own children. Listen to the full interview on the CNBC Sport podcast.
Evolv almost stumbled into what’s now a booming college business
Evolv's frictionless security screening tech is finding a new market in college sports, with Northwestern
Somehow, The Legend Of Zelda Switch 2 Walmart Fumbled Pre-Order Saga Has Gotten Messier
It sounds like the retailer is holding sales back until next week
Auburn's Defensive Line Faces Major Test Against Trinidad Chambliss
Auburn football must improve its pass rush against Ole Miss quarterback Trinidad Chambliss after struggling to pressure LSU's Sam Leavitt. Head coach Alex Golesh wants more consistency from the Tigers' defensive line, especially when rushing four defenders and containing mobile quarterbacks.
Phillies' rotation is set, but they can't procrastinate on adding depth
Late-season injuries left the Phillies searching for innings in back-to-back years. Four possible additions could keep them from scrambling again.
A golden age of science is coming
It’s almost hard to remember, but just a few years ago, a lot of very smart people thought that science was in terminal decline. Respected researchers were writing papers with titles like “Are Ideas Getting Harder to Find?”, “Papers and patents are becoming less disruptive over time”, and “Slowed canonical progress in large fields of science”. In 1996, science writer John Horgan even published a book called The End Of Science: Facing The Limits Of Knowledge In The Twilight Of The Scientific Age. The fundamental idea was that the Universe only has so many insights to discover, and that we’ve picked the low-hanging fruit. It was the idea that Joseph-Louis Lagrange expressed when he said that “we cannot find more than once a system of the world to establish.” As the big ideas and the simple ideas get mined out, we’re forced to throw ever more brains at the mysteries of nature just to keep scientific progress going at a fraction of its old pace: It looked like science was hitting a wall. Then along came AI. It’s far too early to tell how much AI will eventually speed up the growth of total factor productivity. But already we can see signs of a speedup in science. Anthropic Founder Jack Clark assembled some of the hopeful data points in a recent lecture: [ Dror Poleg@drorpoleg "If you pick different parts of science, you see the same pattern show up: Progress is accelerating, and it has started to accelerate in the last two years." Jack Clark @jackclarkSF I’m speaking at the IMF in an hour about the singularity and why I believe it has begun and the choices we'll need to make. Watch live here: https://t.co/Hj9HzcXx5h 6:08 PM · Oct 18, 2026 · 21.2K Views 2 Replies · 10 Reposts · 123 Likes ](https://x.com/drorpoleg/status/2111882070376980529) Anthropic is accelerating its investment into drug discovery, and is already announcing some impressive preliminary results: [ BioTender@Junioryu136689 BREAKING: Anthropic unveils early results from six Claude-powered drug development collaborations. • 70% shorter CAR-T signaling domain • ~35,000 antibody designs • >10× tighter antibody binding • 89% less batch-record review time Still largely preclinical. Anthropic @AnthropicAI Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of 9:43 PM · Oct 27, 2026 · 11.2K Views 3 Replies · 24 Reposts · 205 Likes ](https://x.com/Junioryu136689/status/2115197821150495150) Claude also appears to be enabling rapid progress toward a treatment for food allergies. OpenAI, meanwhile, announced a possible breakthrough treatment for neurodegenerative disease. Meanwhile, Google Cloud Chief Scientist Pushmeet Kohli has a list of recent scientific advances that have been enabled by its new Gemini model, including breakthroughs in nuclear fusion reactor design, rare disease research, and quantum computing: [ Pushmeet Kohli@pushmeet Gemini 4 Argon is a step change in model performance. In recent weeks, it has had a transformative impact on the Science projects in our team at @GoogleDeepMind and our external collaborators, and helped make a number of remarkable advances across scientific disciplines. 🧵👇 4:47 PM · Oct 13, 2026 · 36.5K Views 8 Replies · 41 Reposts · 497 Likes ](https://x.com/pushmeet/status/2110049807385702623) But as cool as these stories sound, they’re just very minor, preliminary efforts. There are a number of reasons to think that AI is going to propel us into a golden age of scientific discovery. That age might not last forever — AI might still run into diminishing returns eventually. But the next few decades are probably going to be an absolutely amazing time for human science. The number of “effective researchers” is no longer limited The most important input into science is scientists themselves. Until this year, that meant human brains — talented, highly trained human brains. The number of trained human brains could be increased by sending more people to grad school, but only to a point — the smartest people tend to be sent into the hardest research fields first, and if you 10x the number of researchers, the average quality will go down. This constraint was already starting to bite, as Ekerdt and Wu argued in 2024: We argue that a substantial portion of the downward historical trend in U.S. research productivity is a composition effect resulting from self-selection in researcher ability and the dramatic expansion of the research sector…[W]e find that this composition effect has lowered average researcher ability by between 37% and 53%[.] And of course, low fertility was making the problem worse, because fewer children meant fewer people who were able to become future scientists. AI just blows up this constraint completely. If an AI agent can function as an autonomous researcher, there’s no constraint on the number of researchers in the world — you can just build more of them, by building more computer chips and data centers that enable the running of more AI agents. Whether or not massive hordes of agents can collaborate to solve individual problems much faster, increasing the number of agents allows them to tackle many different research questions in parallel. What’s more, these AI “researchers” can be trained incredibly quickly compared to human beings. A human scientist takes decades to train, and more years to reach the frontier of their research field by diligent reading and conversation. This is the “burden of knowledge”, and it’s commonly believed to be one reason ideas have been getting harder to find — by the time human scientists can get up to speed, they’re often so old that their ideas are no longer novel. AI just annihilates this constraint — it can assimilate the entire literature and reach the frontier of research extremely quickly, and it can also tell human scientists where the frontier lies without forcing them to discover that for themselves. It can also pivot to new research directions more easily than humans can. And there’s also a self-reinforcing economic cycle here. Because scientific advances enable higher GDP, they enable more resources to be invested into the creation of yet more electronic “scientists”. Now that doesn’t mean the amount of scientific research goes to infinity — there may still be some essential bottleneck task that human researchers are still needed to perform. There are some indications that AI’s progress on open-ended conceptual research tasks is slower than in other dimensions, and it may be that humans are still needed to provide some of this long-term conceptual thinking. I’d bet against this being true for much longer, but it might be true for a long time. Even in this most “pessimistic” case, though, the amount of effective capital that scientists can use to leverage their work just went up by a lot. AI eliminates the theory bottleneck Science proceeds by an iterative process of theory and experiment. The theory part of that cycle is typically short, but non-trivial — it took a couple of years after the blackbody radiation spectrum was observed for Max Planck to come up with the quantum hypothesis to explain it, and decades longer before quantum theory as we now know it was created. It took about a year for Watson and Crick to figure out the shape of DNA after the requisite data was gathered. AI will basically eliminate the theory bottleneck entirely — or at least shorten the turnaround time between experiment and theory by an order of magnitude. AI is an absolute beast at math. Recently, an OpenAI model solved some of the most important open problems in computer science, math, and theoretical physics, and no one even batted an eyebrow because that sort of triumph is becoming increasingly commonplace. One of those solutions was a proof that the Standard Model of Particle Physics could be mathematically well-defined — a problem that human theorists had so far been unable to tackle. Not all research relies equally on theory, but understanding novel experimental results almost always involves some important component of either mathematical or spatial reasoning. That part of the task has now been made much, much faster. And on top of that, science is now open to a greater number of humans who aren’t naturally good at theorizing. AI can read the whole literature Much of the work of human scientists involves reading and understanding endless amounts of papers and going to endless conferences and seminars. The purpose of that work is to understand the existing scientific literature. Understanding the literature allows scientists to do the following things: Come up with new ideas for hypotheses to test Avoid doing research that someone else has already done Synthesize approaches from different areas or fields AI can reduce this effort to almost zero. Consider this excerpt from OpenAI’s blog post about their new research into neurodegenerative disease: The team divided the analysis among thousands of AI agents powered by GPT‑Rosalind, an approach we call distributed biological reasoning. The agents examined a whole-brain CRISPR atlas…a dataset showing how gene disruptions affect different types of cells across the mouse brain. Each agent investigated a gene disruption, analyzed cellular responses, searched scientific literature, and proposed explanations for the results. Their reports were combined into a reasoning atlas linking genes, cellular effects, relevant publications, and possible biological mechanisms. The research team estimated that comparable human analysis and literature review, conducted one perturbation at a time, would take months to a year. The agents reproduced findings from human analyses while uncovering additional leads. Their assessments of novelty and scientific value also aligned with judgments from blinded human experts. These findings help prioritize further experiments needed to test the proposed biological mechanisms. Some of these insights point to new leads for understanding brain disease. [emphasis mine] This is one case in which parallel work by a large number of agents really does make a huge difference: [ Haider.@haider1 this is actually insane openai deployed thousands of GPT-Rosalind agents to analyze millions of mouse brain cells in 32 minutes, work that could take human researchers months to a year also the agents uncovered new leads for brain diseases like Alzheimer's and Parkinson's OpenAI @OpenAI GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in 2:41 PM · Oct 21, 2026 · 51.5K Views 26 Replies · 95 Reposts · 1.26K Likes ](https://x.com/haider1/status/2112917197903540516) Not only does instantaneous literature review vastly speed up the research process, but it allows AI to make novel conceptual leaps from combining approaches from wildly different fields of research. AI regularly does this in math research, combining results, approaches, and theorems from far-flung places that no human mathematician would have thought to combine. It can do it in science, too. Much of scientific innovation, historically, has been “recombinant” innovation — scientists applying insights from one field to another. With AI, essentially all research is now cross-disciplinary — AI can read not just the literature on a particular subject, but the literature on a million other subjects that might have produced useful techniques or insights for the problem at hand. Superscience So far, all of the factors I’ve listed are ways that AI can speed up science as it’s already done. I’ve basically described how AI can send gigantic hordes of superhumanly fast, superhumanly well-read, superhumanly mathematically gifted researchers to re-accelerate scientific discovery. But it’s also possible that AI will enable types of discovery — and ways of understanding the natural world — that no network of humans, no matter how large or how brilliant it was or how long it had to work, would ever be able to discover. In a post back in July, I wrote about how that might work: What if there are lots of…aspects of the Universe that [are] too complex to understand in terms of simple laws, but not so complex that they just dissolve into unknowable chaos? It’s possible that we can reliably control these complex phenomena with AI, even if we never reduce them to the kind of principles that we can teach a grad student in a textbook… Another way of saying this is that there may be laws of the universe that humans can’t understand but AI can. I call these “cloud laws” — causal regularities that can be exploited by technology, but which are too diffuse and complex for an individual human being to either intuit or communicate… Perhaps social sciences like economics, sociology, and political science obey similarly complex regularities, and AI can help us find them. Perhaps there are physical processes — plasma, or topological materials, or aerial turbulence, etc. — that obey cloud laws instead of chaos?… [H]uman collaboration is bottlenecked — it’s limited by our ability to intuit patterns at an individual level, and to communicate these patterns from one individual to another. AI, being a computer, just doesn’t have this sort of limitation; it can work with vast, diffuse patterns without having to break them into pieces or simplify them in order to compress them into the tiny pipelines of person-to-person explanation… If much of the Universe turns out to be ruled by cloud laws, we could be on the precipice of a scientific renaissance. In order to discover cloud laws, AI will need huge amounts of data about the natural world. AI figured out human speech by assimilating essentially all of the text humans have ever written. If it’s going to figure out hidden patterns in biology, neuroscience, materials science, etc., it’s going to need similarly massive amounts of data from physical instruments. That data will be far, far more than humans — individually or collectively — would be able to parse, label, characterize, or model. But AI was built to do this. If scientists simply build huge arrays of sensors to measure complex phenomena like the brain, the cell, the economy, etc., they may be able to feed this flood of data to AI directly and bypass human cognitive intermediation entirely. AI would then learn about the world directly, and it might learn things that humans never could. This “superscience”, if you want to call it that, would actually go beyond the kind of science humans have done heretofore. Many of the technologies it yielded would be beyond human comprehension — indistinguishable from magic. But to the AIs, they would make perfect scientific sense. In any case, it seems clear that the scientific slowdown that threatened human progress will now be delayed — at least for a while. Unless humans have somehow found most of the actual exploitable regularities in our Universe, we’re about to enter a new golden age of science. Subscribe Share
Giants should resist an expensive Jonathan Taylor gamble
Jonathan Taylor is an easy player to dream about in the Giants backfield. Paying for that dream is the harder […]
Justice Department makes a splash with politically sensitive cases and actions during midterm blitz
President Donald Trump’s Justice Department has been scrambling before the midterm election with a blitz of headline-making actions and cases that some critics say reeks of politics
Villa Vie Odyssey passengers describe abrupt cruise shutdown
After the Villa Vie Odyssey halted operations, residents say they were left scrambling to find hotels and retrieve their belongings in Cambodia.
Hybrids coming to GM plant in Michigan, automaker says
General Motors Co. will produce hybrids at its Lansing Delta Township Assembly plant near Michigan's capital, as it seeks to catch up in an electrified vehicle segment that has enjoyed
Ensemble Returns to Federal Lobbying on Science
Ensemble Government Services files a new Science/Technology lobbying registration with Ervin Graves Strategy Group, after a 15-month gap. Get the details.
Marlo Vernon: An unstoppable force for rural health across Georgia
“Just knowing that everything we’ve done has brought us to this point is incredibly exciting and humbling,” says Marlo Vernon, PhD.
Star Entertainment hit with £137 million anti-money laundering fine
A federal judge has slapped one of Australia’s largest casino operator with a hefty penalty over ‘egregious’ anti-money laundering violations while warning other industry players non-compliance is ‘not worth the risk’.
Size matters: South Korea spared iPad mini image's potentially offensive gesture
Apple has chosen to use a different image in South Korea to promote the iPad mini in South Korea, likely over fears that the version used the rest of the world might resemble an offensive gesture mocking the size of someone's manhood.
Politicians are afraid to fix taxes. So 100 citizens tried.
Connecticut’s property tax system has been broken for decades and the politicians have failed to fix the problem. So now, they’re trying something new: a citizens assembly. (Citizens assemblies are also old. They go back to Ancient Greece, when lawmakers were chosen not through elections, but through random lotteries.) Today on the show, Connecticut’s citizens assembly. It's like jury duty, but for taxes. About hundred random people from all around Connecticut come together to try to solve the state’s property tax problem. They wrestle with whether they should raise taxes, cut spending, find efficiencies, or a mix of everything. Will this alternative attempt to solve the unsolvable succeed, or will it be politics as usual?It’s a modern case study of what happens when politicians step aside to let citizens decide what’s best. Come along as we talk to the professor who helped put this assembly together, learn from the citizens involved how this experiment changed them, and meet the politician who agreed to take their proposals to the state legislature. Planet Money will be at Kilkenomics Festival 2026. Tickets here.Read: - Our book: Planet Money: A Guide to the Economic Forces That Shape Your Life - Our weekly longform Planet Money newsletter- Our weekly Indicator round-up newsletterFollow: - Instagram- TikTok- YouTube- FacebookSupport public media with NPR+ and enjoy perks for over 25 podcasts like this one. This show’s perks include bonus episodes and sponsor-free listening. Learn more at plus.npr.org.This episode of Planet Money was hosted by Erika Beras and Jeff Guo. It was produced by James Sneed with reporting help from Áine Pennello. It was edited by Jess Jiang, Sierra Juarez is our fact-checker, and Jimmy Keeley & Travis Hagen engineered the show. Alex Goldmark is the executive producer of Planet Money..
A single sauna session sends immune cells surging through your body
A new Finnish study reveals that just 30 minutes in a sauna can temporarily flood the bloodstream with additional white blood cells, potentially helping the immune system patrol the body and detect threats. The surprising response resembles the immune boost seen during exercise and may help explain some of the health benefits linked to sauna bathing.
What does an elected school board mean for Chicago? More politics, experts say.
The Chicago school board campaign has become typical rough-and-tumble politics and candidates are throwing punches.
What does an elected school board mean for Chicago? More politics, experts say.
Chicago’s push for a fully elected school board promised more community voice. Days out from the historic vote, the race also has become a new venue for the city’s infamously rough-and-tumble politics...
Polymarket’s top trader is sports gambler ‘Swiss Tony’
FT analysis shows biggest winners on prediction platform are a mixture of long-shot bettors and high-frequency traders
“The Spooky Science of Pipe Organs”
On Saturday, Oct. 24, the National Music Museum (NMM) hosted a Halloween-themed event featuring songs performed on a 200-year-old pipe organ. The event included a chance to discover how pipe organs work through the NMM’s “Organ Experience,” showcasing how a miniature, fully functional pipe organ is assembled by Anna Van Kley. Van Kley […]
Timberwolves’ Anthony Edwards Raises Sports Gambling Concerns in $14K-a-Month Child Support Dispute
The Minnesota Timberwolves’ Anthony Edwards is seeking changes to how part of his child support payments would be managed, citing concerns about sports gambling. According to TMZ’s reporting on court documents, Edwards asked for a trust to receive a portion of the money and a trustee to oversee distributions. The mother of his child, Alexandria […] The post Timberwolves’ Anthony Edwards Raises Sports Gambling Concerns in $14K-a-Month Child Support Dispute appeared first on HEAVY.
Animals Starves while the Kardashians Miss the Charts Again
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Before we get going, I’d like to offer congratulations to Jonathan Funke, whose suggestion “midflicks” won the poll for what I should call straight-to-streaming films which aren’t big or cinematic enough to go to theaters but seem too expensive for a TV movie. It’s so useful a term, I just used it last week! Now I just need to add this term to my data dictionary! Okay, on to this week’s issue. We’re starting out looking at Netflix/Ben Affleck’s latest crime thriller, Animals. I’ll also look at Disclosure Day heading to Peacock (it did better than you’d remember in theaters...) and a new movie based on toys. Plus, a long-time streaming flop returns for its eighth season...will it finally chart? (No.) Will anyone at Disney care? Probably not. All that, plus another look at new shows landing on streaming on 1-Oct from Reelgood, what streamer hasn’t had a film make the Luminate charts since August, Reacher’s long run on the charts, M_onster: The Lizzie Borden Story’s_ short run, the top shows in 2026 according to Samba TV, all the flops, bombs and misses, and a whole lot more. And I mean that last part: putting this week’s issue together, I assembled OVER 25 images, most of which are bespoke looks I made just for this report. Really, publishing articles like this takes the work of writing two articles: one is the narrative and the other is making charts/graphs. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the week of October 5th to October 11th, 2026. You can find a link to my terminology here.) Subscribe Film - Netflix’s Latest Star-Studded Thriller Goes For Glory The tempting angle for anyone writing about streaming film this month, like yours truly, is to ask, “Is this why Dan Lin lost his job at Netflix?” Take Animals, the Ben Affleck-starring-and-directing, Artists Equity-produced crime thriller that opened on 9-Oct. (Kerry Washington and Gillian Anderson are also in it.) If it did really well, then one could argue that Lin has another success on his resume. If it underperformed, then it’s another example of a Netflix underperformance this year. So where did Animals fall? Kinda in the middle, but that means it’s more “not a hit” than “big hit”. On Nielsen, it opened to 12.0 million hours, and here’s how that stacks up for 2026 films so far this year: Obviously, that’s not great. It’s both under my 15 million opening bar for “fine” for a Netflix film and 20 million bar for “great” opening. It did a bit better on Samba TV, getting to first place. That’s very, very good, though again, looking at the Nielsen data, it probably means that it was a light week overall. Luminate’s data is a bit closer to Samba TV’s, tied for 17th all time for single weeks since May of 2024: To top it off, no one seemed to like it. It has a 33 on Metacritic and only a 5.7 on IMDb. Both of these numbers could have been impacted by the stories about Affleck’s comments about using AI to make the film. Given the controversy, the film might not have been as bad as the ratings suggest, but it’s also not a bullish sign. All to say…yeah, on net this film isn’t a point in Dan Lin’s favor. At this point, Netflix’s slide has been long enough—going on since February—that I’m almost tempted to lower the bar for what a “hit” is on streaming. Post-February of 2026 or so, it seems like straight-to-streaming films just haven’t hit the same heights as they did from 2022 to 2025. Before we head onto the “Quick Hits” for film, I want to shout out a fellow newsletter whose articles I’ve been loving this year, LA Material, a new LA-based news outlet. For just a highlight of my favorite articles since July... I loved this article on Ghost Town, a group on Venice that clears homeless encampments. As a Los Angeleno, obviously I adore their articles on LA parking issues. Their article on illegal parking tickets got the City Council to address the issue! Also check out their article on people parking in medians. Check out their deep dive on what went wrong with the LA Jazz Festival and how it fell apart, or what’s wrong with USC’s finances. Finally, they wrote up a voter guide on voter guides for the LA General Election. So meta! In search of a city? L.A. Material is an independent news outlet covering the people, politics, culture and glorious chaos shaping Los Angeles. L.A. Material brings you intel on the city you can’t get anywhere else. From exploring how Reddit short stories became Hollywood’s hottest commodity to reporting on the survival jobs keeping entertainment workers afloat. And answering, once and for all, why the AMC Burbank escalator is always broken. Through their newsletters, podcast, videos, events, and member community, L.A. Material is designed to help Angelenos connect to Los Angeles and each other. Sign up now for the free weekday newsletter. Quick Notes on Film Steven Spielberg’s latest film, Disclosure Day, came to Peacock on 9-Oct, and I’ll admit that, after pulling its stats, I did a pinch of a double take. As I wrote throughout my deep, deep, deep dive on summer box office/Obsession/Backrooms/IP/superheroes, oftentimes the film media discusses films as “flops” or “misses” or “hits” without clarifying what they specifically mean. Since Disclosure Day didn’t make $250 million in the US or $500 million globally, it was definitely a disappointment by Spielbergian standards, who is the highest-grossing director of all time, and arguably even more ahead in adjusted grosses. But it did make $245 million globally on a $115 million budget, so it isn’t as big of a miss as I remember. That’s still probably not enough to break even in the theatrical window, when you factor in marketing costs…but it’s close. And it grossed a lot more even in the US than some titles with about ten times more coverage. Anyways, lots of preamble to say this one only did 4.5 million hours according to Nielsen, so it did make the charts, but on the low end. Here’s how it stacks up to other Peacock titles: Apple TV (née +) followed up their “success for them” Mayday with Matchbox The Movie. This one doesn’t look like a success even for them, but at least it’s not a miss. Apple/Skydance clearly tried to take advantage of the success of Barbie at the box office—let’s greenlight all the toy properties!!!—but of course, this didn’t make it to theaters. And it stars John Cena, who, as I argued earlier this summer, NEEDS to get his movies back in theaters. Anyways, this one has mixed-to-bad numbers. It missed the Samba TV and Nielsen charts in its first week, but did make Luminate with 7.1 million hours. That’s just enough to not be an outright miss, and about half what Mayday did earlier this summer. Speaking of Apple Studio’s Mayday, it ended up lasting five weeks on Luminate, which isn’t bad for Apple TV. On Nielsen, it had a three-week run, racking up 13.5 million hours total. Again, like Matchbox, the issue is the budget; I doubt that this viewership earned enough to justify that budget. Also, to be clear, neither of these films are “midflicks”; both should have gone to theaters. Toy Story 5 is not hanging around on the streaming charts on Disney+, so it’s not as leggy as either Zootopia 2 or Moana 2, and definitely not in the same class as Encanto. (It did make all the money at the box office, so Disney is going to be fine…) The Breadwinner on Netflix (from Sony) is down to 3.9 million hours in its third week. It only lasted for one week on the Samba TV charts. Netflix’s Doing Life had a smaller-than-normal binge release curve bounce, only going to 7.1 million hours from 6.0 to start, but it made Samba TV at fifth place in its second week. The Netflix documentary, The Widower: Til’ Death Do Us Part, also had a small binge release curve bounce to 6.5 million hours, but did make a second week on Samba TV. Meanwhile, Netflix’s Unabomber fell off after two weeks on Nielsen—which is not great at all—and Demon Slayer fell off after just one week. Over on Luminate, the two smaller titles The Swan: Behind the Mirror and Kill. Bury. Print both fell out of the Luminate top ten charts. The story of library film at the first of the month is the arrival of the Ice Age films on Netflix. Now, here’s a small example of optimizing your library that even Netflix could do better. Say you want to rent/license a new film series from Disney**.** A streamer could pay a big paycheck and then drop each Ice Age film on the exact same day of the month, the fourth of October. That’s one choice. In contrast, the streamer could have released each film one week apart, and make each one a mini-event for folks watching Ice Age films. Or even roll them out monthly. Netflix opted for the former strategy, and as a result, only three of the films made the Nielsen charts this week. The “Miss of the Week” goes to Tubi’s YA-ish horror film_, R.L. Stine’s Pumpkinhead 2_, which didn’t even make the Luminate charts like Tubi films usually do, or, should I say, “used to”? Tubi films, most of which are straight-to-streaming, used to reliably make the Luminate film charts (which only covers straight-to-streaming films), but a Tubi film hasn’t made it since August. The first Pumpkinhead got 1.4 million hours last year according to Luminate. As I wrote about this film before, it seems to be a bit muddled in terms of age: too scary for young kids but probably not scary enough for older kids. Speaking of Luminate, Netflix’s latest doc about a comic (expect more docs about comedians all month), Who Is Martin Mull?, flopped, getting just 200K and 700K hours according to Luminate. Three other film/special misses belonged to Hulu, including a standup special, Jamie Foxx: Take Care of Yourself, Neon’s latest horror film, Hokum, which made $17 million in the US, and a Family Guy Halloween special. (That last one was only 22 minutes, so it’s not a surprise it missed.) Finally, another Netflix standup special missed the charts, Mojo Brookzz: I Know You Lying missed too. I can confirm last week’s misses, most notably Paramount+’s Jackass: Best and Last, MUBI’s Teenage Sex and Death at Camp Miasma and HBO Max’s Evil Dead Burn. Television - I Can’t Visualize Nothing: The Kardashians Story Normally, in the mini-dive essays that open the Streaming Ratings Report, I focus on shows that do well or, at the very least, make the charts. Why? Because as I’ve said time and again, I can’t visualize nothing like, say, the Kardashians’ TV shows. Here’s the TV debuts chart for this week with a missing spot for The Kardashians, whose eighth season just landed on Hulu:
NWH Community Collaborative Annual Assembly showcases the power of unity in community health
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Vocal Art Ensemble spins fairytale with ‘Bluebird’
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How Serious Is Jannik Sinner’s Knee Injury?
Jannik Sinner has not played a competitive tennis match since winning Wimbledon in July, and there is now a very real possibility that his recovery could prove more complicated than initially anticipated. The Italian announced earlier this month that he would miss the remainder of the 2026 season because of persistent inflammation in his right …
N.C. Residents Inundated with Mailers Urging Them to Vote. Here's What to Know.
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LeBron James, Adam Silver and the NBA’s BIG BET: Is Basketball Walking Into a New Sports Gambling Era?
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How worried should Spurs be amid sluggish 1-2 start?
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‘It affected my health’: Neighbors complain about building implosion, cloud of dust
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Annual Kansas Speaks survey shows distrust in politics but support for Gov. Laura Kelly
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What Is the Relationship Between Doing Good History and Entertainment?
[Cross-posted from The Tattooed Historian’s Dispatch] What exactly are we doing when we communicate history to the public? Most of us would agree that accuracy matters, evidence matters, context matters, historical rigor matters. But we also live in a world where attention matters (and attention spans are dropping at an alarming rate). Subscribe Whether we’re posting on social media, producing videos, hosting podcasts, giving public talks, or designing museum programs, we’re all competing with countless other demands on people’s time. The public doesn’t simply stumble into history anymore. Now, good history has to find people where they already are. This raises a difficult question: Is making history entertaining part of good historical practice, or is it simply what we must do to remain relevant? “Entertainment” is often treated as the opposite of seriousness. But what do we mean when we use the term itself? Does entertainment mean simplifying the historical record? Does it mean telling compelling stories in a lively manner? Is there a difference between being engaging and being entertaining? And who gets to decide where that line is? Share These questions become even more complicated online. Social media platforms reward attention. Algorithms reward engagement (the positive and the negative). Visibility often depends on producing content that people are willing to click, watch, share, and discuss. What happens when those incentives shape the way history is presented? Can historians work within those systems without letting those systems define the work? Are public audiences being served better than ever before, or are platform incentives changing what kinds of history rise to the surface? These are just a few of the issues that I discuss with John R. Heckman in our latest installment of “Historians Off the Cuff.” Feel free to suggest future topics for us to discuss in the comments section below. Hope you are entertained. LOL Civil War Memory is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
New Jersey Cannot Prescribe Better Health Without Making Healthy Food Accessible
By Assemblyman Kenyatta Stewart We tell people with diabetes to watch their blood sugar. We tell people with hypertension to reduce their sodium. We tell families to eat more fruits and vegetables to prevent chronic disease. But what happens when the food we recommend is beyond their budget or unavailable in their neighborhood? That is[...]
The NBA is having second thoughts about sports gambling
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NEO Surveyor’s Sunshade Gets Inspected
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D.J. Wonnum’s Block Rescued Dan Campbell’s Fourth-Down Gamble
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Is the Brewers Postseason Comeback Gimmick Sustainable?
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Pricey cookie vendor closes dozens of locations nationwide
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Thune campaigns for Republicans in marquee Senate races in scramble to save majority
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Microsoft releases emergency .NET security fixes for Google Brotli bug
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Penn State, Matt Campbell Hit With Bad Recruiting News
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Mike Tomlin Makes Campbell’s Gamble About Goff vs. Love
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Microsoft is offering buyouts. Read the memo.
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Lula celebrates election win as Brazil markets tumble
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Selecting WHO Director-General: The Job Nobody Has Described (Part II)
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New zebrafish models could help test treatments for mental health conditions
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Xbox Game Pass adds new day-one title Scramble Knights Online today
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Georgia Opens as Overwhelming Favorites vs. Florida
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County parks
The Redwood City Elks Lodge No. 1991 hosted a packing day event to assemble and care boxes for deployed troops and care bags for at-risk veterans on Saturday, Oct. 17.
Is Lions coach Dan Campbell taking too many risks?
The Detroit Lions are winning football games, but should Dan Campbell tone down the gambling?
Michigan Medicine’s new AI chief joins a fast-growing club of hospital executives
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Michigan Medicine’s new AI chief joins a fast-growing club of hospital executives
The fast-paced ramp-up of AI and financial pressures have health systems scrambling to find an executive to oversee adoption and implementation.
OpEd: World Needs U.N. Convention on AI
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Cris Collinsworth Turns Heads With Unusual Praise of Patrick Mahomes
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Cubs Trade Of Edward Cabrera An Early Lose-Lose Deal
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49ers' First Loss Makes It Clear: Their Toughest Opponent Is Their Health
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British Columbia's new premier lucks into the job in unexpected political turn
An electoral gamble by the Canadian province's outgoing premier, David Eby, backfired as the provincial Conservatives take power for the first time since 1928.
BC's new premier lucked into the job in an unexpected political turn
An electoral gamble by the Canadian province's outgoing premier, David Eby, backfired as the provincial Conservatives take power for the first time since 1928.
NFL Week 7 Sunday afternoon open thread
Join us at Buffalo Rumblings as we chat all things NFL Week 7 LIVE with like-minded folks in Bills Mafia
ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Clemson HC Dabo Swinney Waving White Flag on Season
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Iain Armitage says “Young Sheldon” cast drove each other ‘crazy’ while shooting season 3 opening credits
The ensemble would ‘drive each other nuts.’
Iain Armitage says “Young Sheldon” cast drove each other ‘crazy’ while shooting season 3 opening credits
The ensemble would ‘drive each other nuts.’
As vote nears, Trump’s AI gamble fuels economic uncertainty
Some of the world’s leading financiers are sounding increasingly alarmed about an AI bubble.
🎥 He's already on a yellow! Linesman sends player tumbling
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Guest Commentary: How anti-Muslim politics endangers every Floridian
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He Took Big Risks to Make Billions. He Wants Georgia Voters to Bet on Him.
Rick Jackson’s run for governor as a political nobody was his latest gamble. The campaign has brought scrutiny to the businesses that made him a fortune.
He Took Big Risks to Make Billions. He Wants Georgia Voters to Bet on Him.
Rick Jackson’s run for governor as a political nobody was his latest gamble. The campaign has brought scrutiny to the businesses that made him a fortune.
Demichelis' Gamble Pays Off As Leipzig Crush Elversberg 4-0
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TST Best Bets: October 24, 2026
A full week later, it’s still hard to wrap my head around what we witnessed in college football last week.In unprecedented fashion, five of the top seven nationally ranked teams lost outright, throwing the sport’s balance of power into disarray.A lesser gambler might want to stay away from college football this week until things settle down, but we remain undaunted.For all of your college football betting picks, here are today’s TST Best Bets, brought to you by BetOnline.ag. Click here to join.
How cancer has scrambled Iowa’s midterm politics
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House Republicans are scrambling to save incumbents in districts Trump won by double digits
Payroll Delay Unnerves Staff at Randolph Health
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Creative Assembly Finally Addresses The Shogun 2 Remaster Disaster By Pointing Fingers
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Business owner arrested in connection with illegal gambling and drug case
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"This was not a Creative Assembly developed game": Total War boss points the finger at external partner for Shogun 2 Complete Edition disaster
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Humble ISD to unveil 'Magic Science Lab'-themed playground at Ridge Creek Elementary
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Giants Must Attempt to Sign Morejón
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