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Pfizer makes ‘business decision’ to end phase 2 trial of autoimmune drug as program’s future uncertain

Pfizer has called time on a phase 2 trial of its CXCR5 antibody in an autoimmune blood disorder, with the company tight-lipped on whether this marks the end of the road for the asset. The Big Pharma had been evaluating the therapy, dubbed PF-06835375, in a phase 2 study of 61 patients with primary immune thrombocytopenia (ITP) that kicked off in 2022, according to the federal trials register. However, Pfizer confirmed to Fierce on Monday that this study had been terminated “due to a business decision.” “The decision to terminate the trial was not based on any safety concerns,” a spokesperson pointed out. At time of publication, PF-06835375 remained listed on Pfizer’s website for both ITP and lupus. A phase 1 study in lupus wrapped up in 2022, according to the trials database. ITP is an autoimmune disorder characterized by a low platelet count. Novartis was at one point evaluating its B-cell-depleting antibody ianalumab—recently approved as Fabhalta to treat immunoglobulin A nephropathy—as a potential treatment ITP. But the therapy struggled to demonstrate a benefit in the clinic for this indication. When contacted by Fierce, Pfizer wouldn’t confirm whether all work on PF-06835375 has been halted, and whether the company has any other plans to explore C-X-C chemokine receptor type 5 (CXCR5) as a mechanism. CXCR5 is found in blood cancers such as diffuse large B-cell lymphoma and mantle cell lymphoma chemokine receptor. However, there is little expression in normal tissue, which has led some drug developers to explore its potential. Vincerx Pharma had at one point been planning to take an anti-CXCR5 ADC into the clinic to treat B-cell malignancies, but that ambition was scrapped due to cash constraints. Where Big Pharma is placing its bets is one of the hot topics being discussed at Fierce Biotech's high-impact event in London next month. Find out more information and register by clicking on the banner below: [ ](https://qtxasset.com/quartz/qcloud5/media/image/where_big_pharma_is_placing_its_bets.png?VersionId=B8JrRbJ.pFUSK1pJgjeWHLGm_18RdLAy)

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Oct 20 • 3:59 AM EDT • Business • fiercebiotech.com
Roland n/vision Review: Vision for the Future or Late to the Party?

The new Roland n/vision is the company’s first true wavetable synth. Can the latest addition to the Boutique series hold its own against the competition?

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Oct 20 • 3:00 AM EDT • Technology • gearnews.com
Week 6 Linebacker Usage and Review

Steve Hungarter uses defensive snap percentages from Weeks 4-6 with other season-to-date data to analyze off-ball linebackers entering Week 7.

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Oct 20 • 1:41 AM EDT • Sports • sports.yahoo.com
Mutts

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Take it From the Tinkersons

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Marmaduke

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Peanuts

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
For Better Or For Worse

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Sudoku

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Blondie

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Oct 20 • 12:00 AM EDT • Entertainment • thederrick.com
Grading every Padre on 40-man roster

Roster Review: Jason Adam

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Oct 19 • 11:05 PM EDT • Sports • sports.yahoo.com
PSG vs Barcelona, Champions League: Preview

A massive European test

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Oct 19 • 11:00 PM EDT • Sports • sports.yahoo.com
In tight WA House race, sparks fly over safety at challenger’s business

Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.

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Oct 19 • 9:59 PM EDT • Business • seattletimes.com
In tight WA House race, sparks fly over safety at challenger’s business

Questions about safety at Braun Northwest have become a flashpoint in a Southwest Washington district grappling with a deadly tank collapse at a Longview mill.

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Oct 19 • 9:59 PM EDT • Politics • seattletimes.com
Former Las Vegas Councilwoman denies misusing donations during judicial discipline hearing

Michele Fiore testified that she believed a developer paid for a memorial statue honoring slain Metro officer Alyn Beck as she denied misusing donations during a Nevada judicial discipline hearing.

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Oct 19 • 9:22 PM EDT • Politics • reviewjournal.com
Franklin Publishes Book Review in <em>Political Theory</em>

A. Todd Franklin, the Eugene M. Tobin Distinguished Professor of Philosophy & Africana Studies, has published a review of Michael J. Illuzzi's Mending the Nation: Reclaiming "We the People" in a Populist Age (University Press of Kansas, 2025) in Politica

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Oct 19 • 8:00 PM EDT • Politics • hamilton.edu
The Most Efficient Way to Tax Sports Betting

Most US states have legalized this quickly growing business.

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Oct 19 • 7:30 PM EDT • Sports • chicagobooth.edu
🙂 Positive (44%)
President Trump talks data centers and staying in politics with Tricia Macke

FOX19 NOW’s Tricia Macke interviewed the president on one of the most contentious topics Tri-State residents

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Oct 19 • 6:48 PM EDT • Politics • fox19.com
U.N.C. Strikes Trump Deal to Keep Federal Funding

The University of North Carolina at Chapel Hill will not pay any financial penalties but agreed to abide by the Trump administration’s views on diversity and other matters.

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Oct 19 • 6:42 PM EDT • Politics • nytimes.com
Melco Resorts & Entertainment Limited Stock 12‑Month Price Target Cut to $6.14, Implies 48% Upside

Explore more price target data and ratings for Melco Resorts & Entertainment Limited on the Forecasts tab, and track all previous and future analyst recommendations for Melco Resorts & Entertainment Limited in the dedicated News Flow.Select reference data provided by FactSet. Copyright © 2026 FactS…

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Oct 19 • 6:20 PM EDT • Entertainment • tradingview.com
How forensic science opened a student’s eyes to agriculture

Forensic science degree leads Texas A&M College of Agriculture and Life Sciences student toward law, policy and a broader view of agriculture

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Oct 19 • 6:07 PM EDT • Science • agrilifetoday.tamu.edu
Five Cybersecurity Areas for Review This Month » CBIA

Cybersecurity conversations often stay with IT until a disruption affects operations, reporting, customer relationships, or decision-making.

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Oct 19 • 6:06 PM EDT • Business • cbia.com
Iowa 55-hour ‘FilmSprint’ comes to Cedar Rapids this fall

Cedar Rapids Independent Filmmakers launches the Iowa 55-Hour FilmSprint, Nov. 6-8, 2026, challenging teams to write, shoot and edit a short film with Iowa-themed secret elements.

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Oct 19 • 6:00 PM EDT • Entertainment • thegazette.com
Tandana Foundation to host Dogon culture event in Mancos in November

Evening will feature storytelling, music and more

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Oct 19 • 5:52 PM EDT • Entertainment • the-journal.com
‘Euphoria’ star Hunter Schafer underwent bottom surgery

NEW YORK — “Euphoria” star Hunter Schafer revealed in an interview published Monday that she recently underwent a genital reconstructive procedure to align her identity and gender. “I just had

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Oct 19 • 5:52 PM EDT • Entertainment • recorderonline.com
President Trump talks data centers and staying in politics with Tricia Macke

President addresses property tax concerns and reflects on staying in politics during interview with Tricia Macke.

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Oct 19 • 5:47 PM EDT • Politics • fox19.com
Texas Democratic candidate for governor sues to review emails between Elon Musk and Greg Abbott

State Rep. Gina Hinojosa alleged in her lawsuit that Gov. Greg Abbott is “unlawfully withholding communications” between his office and tech CEO Elon Musk.

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Oct 19 • 5:30 PM EDT • Politics • nbcnews.com
High-Signal Publisher
Fifth annual ¡ARTE VIVA! celebrates Hispanic arts, culture

Embark on a journey into the vibrant heart of Hispanic arts and culture as Florida's Paradise Coast offers another year of exhilarating celebration of ARTE VIVA! , presented by the

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Oct 19 • 5:30 PM EDT • Entertainment • floridaweekly.com
Mines Museum of Earth Science event makes science spooky

Not many Halloween events send trick-or-treaters home with geodes, but the Mines Museum of Earth Science’s annual Spooktacular is one of them.

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Oct 19 • 5:19 PM EDT • Science • thegoldentranscript.com
Mines Museum of Earth Science event makes science spooky

Not many Halloween events send trick-or-treaters home with geodes, but the Mines Museum of Earth Science’s annual Spooktacular is one of them.

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Oct 19 • 5:19 PM EDT • Science • westminsterwindow.com
Republicans pull funding in Ohio’s 1st District as race shifts toward Democrats

The district was once considered one of the most competitive in the country, with both parties viewing it as key to maintaining control of the House.

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Oct 19 • 5:15 PM EDT • Politics • spectrumnews1.com
UCCS Business Forum Preview

The UCCS Economic Forum will be October 28th.

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Oct 19 • 4:08 PM EDT • Business • kktv.com
‘Topdog/Underdog’ revival opens Steppenwolf's 51st season

When I reviewed the Chicago premiere of “Topdog/Underdog” at Steppenwolf Theater in 2003, I suggested that Suzan-Lori Parks' play about the rivalry between two Black brothers didn't deserve its 2002

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Oct 19 • 4:00 PM EDT • Entertainment • hpherald.com
Rural Health, Inc. to hold 5th annual Night of the Living Health Fair on Friday

Rural Health, Inc. will hold its annual Night of the Living Health Fair on Friday, inviting the community to trick or treat while also learning about Southern Illinois healthcare services

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Oct 19 • 3:56 PM EDT • Health • wpsdlocal6.com
AMD Ryzen AI Halo Review - Local-AI Powerhouse with 128 GB of Memory

The AMD Ryzen AI Halo is great at running local AI workloads, featuring a Ryzen AI Max+ 395 APU with 128 GB of unified memory in a compact form factor. It excels at handling large models, enabling tasks that most consumer GPUs struggle with. With AMD AI Playbooks, getting started is simple, allowing you to explore the frontier of AI at home.

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Oct 19 • 2:00 PM EDT • Technology • techpowerup.com
Trump Wades into Israeli Politics

Netanyahu is stumbling toward the finish line of this election cycle with Israel isolated internationally more than ever before, as major European partners have all but turned their backs on the Jewish state, and a majority of Americans view Israel negatively.

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Oct 19 • 1:48 PM EDT • Politics • momentmag.com
The Chase still has NASCAR chasing its former viewership

While NASCAR reintroduced its final stretch run, The Chase, to rekindle postseason interest, viewership for the races has remained lackluster. Over six races, the 2026 NASCAR Cup Series Chase averages 1.62 million viewers, up just 1% year over year (1.61 million), per NASCAR Communications. So far, The Chase hasn’t delivered the viewership renaissance NASCAR hoped…

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Oct 19 • 12:00 PM EDT • Sports • sports.yahoo.com
Announcing Call for Editors: American Political Science Review (APSR) -

The American Political Science Association (APSA) invites applications for the editorship of American Political Science Review (APSR), with a term beginning on June 1, 2028. APSR is one of the Association’s flagship journals now in [...]

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Oct 19 • 12:00 PM EDT • Science • politicalsciencenow.com
PlayStation 6 RAM and Storage Alone May Cost $680, According to Leaker

The PlayStation 6 hasn't even been announced yet, but little rumors pop up now and then that add speculation on what to expect from Sony's next-gen console. The latest is a shocking claim that the RAM and storage configuration of the console will cost more than the entirety of the PS5.

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Oct 19 • 11:51 AM EDT • Technology • ign.com
Supreme Court to Hear New Case on Race and School Admissions

The court’s decision to review an admissions policy for selective middle school programs in Maryland follows its rejection of affirmative action in higher education.

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Oct 19 • 11:38 AM EDT • Politics • nytimes.com
Dizzying lineup of Galaxy Z Fold 9 devices leaks, including the Galaxy Z ‘Slide’

The Galaxy Z Fold 9 lineup looks complicated. Not only does Samsung reportedly plan to add another Fold model, but...

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Oct 19 • 11:32 AM EDT • Technology • 9to5google.com
'Other Desert Cities' review: Julia Louis-Dreyfus debuts Broadway

A revival of Jon Robin Baitz's 'Other Desert Cities,' directed by John Benjamin Hickey, opens at Broadway's Hudson Theatre with a cast that includes Julia Louis-Dreyfus, Ed Harris and Allison Janney.

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Oct 19 • 11:24 AM EDT • Entertainment • latimes.com
Boston vs. Bullies Uses Sports and Star Athletes To Curb Bullying In Schools

Athletes from nine different Boston pro teams serve as representatives for the program.

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Oct 19 • 11:00 AM EDT • Sports • usahockey.com
Review: Miley Cyrus is an ambivalent comeback queen

LOS ANGELES — "For me, performance can't be everything," Miley Cyrus declared on Friday night, and you had to admire her choice of setting: onstage at the Hollywood Bowl in

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Oct 19 • 10:52 AM EDT • Entertainment • recorderonline.com
Suburban women souring on Paxton could doom him in tight race

Interviews with these voters reveal a combination of apathy toward his candidacy and an active shift by some toward his Democratic opponent.

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Oct 19 • 10:48 AM EDT • Politics • detroitnews.com
EXCLUSIVE: Sports Betting No More Addictive Than Stock Trading, Smarkets CEO Says

Sports betting is no more addictive than stock trading, and financial brokers should face similar obligations to protect vulnerable customers, Smarkets CEO Jason Trost told Benzinga in an exclusive interview. “I don’t think sports betting is any more addictive than...

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Oct 19 • 10:43 AM EDT • Sports • finance.yahoo.com
2026 Election Preview: 6th Senate District

The midterm elections are less than two weeks away and PoliticsPA has identified seven State Senate races throughout the Commonwealth to focus on during the run-up to the 2026 election, as part of our 31 Races in 31 Days series. SD-6: Frank Farry (R) vs. Eileen Albillar (D) The Key…

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Oct 19 • 10:42 AM EDT • Politics • politicspa.com
Essentia Health hosting Hypertension Night

There, attendees can get their blood pressure checked, receive educational materials, have experts review your medications and have an at-home blood pressure cuff calibrated.

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Oct 19 • 10:40 AM EDT • Health • essentiahealth.org
😐 Neutral (0%)
THE WEEK OF OCT 19, 2026

- Lawmakers eyeing university research security - DHS proposes more visa changes - NIH considers hiding peer review scores

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Oct 19 • 10:31 AM EDT • Science • aip.org
Eumathian Club explores art, science

The Eumathian Club’s September meeting featured an art lesson with Pam Chamberlain at her studio in Hico, following lunch at the Koffee Kup and a visit to the Wiseman House

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Oct 19 • 10:30 AM EDT • Science • cleburnetimesreview.com
Deep dive
😐 Neutral (8%)
wow
57%
ahah
43%
Would never do it again: Ex-international regrets Germany decision

Former Germany international Kerim Demirbay regrets his decision to play for the German national team. The 33-year-old said as much in an interview with Turkish journalist Yağız Sabuncuoğlu, in whi...

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Oct 19 • 10:30 AM EDT • Sports • sports.yahoo.com
☹️ Negative (-10%)
ahah
100%
Meghan McCain fires back at ‘View’ star Joy Behar’s ‘mean girls’ remark about past cohosts

Meghan McCain fired back at ‘The View’ cohost Joy Behar after the panelist’s remark about ‘mean girls’ at the Hot Topics table: ‘You guys keep asking me for a response.’

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Oct 19 • 10:22 AM EDT • Entertainment • ew.com
“The Earth is 6,000 years old.” How science debunks this religious view
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Oct 19 • 10:15 AM EDT • Science • yahoo.com
Under new management: Oak View Group takes the reins at Riverview Health Arena

Following an inaugural year that saw more than 60,000 visitors and 70 events, the City of Noblesville is handing operations of Riverview Health Arena at Innovation Mile to Oak View Group. The transition marks a shift from REV Entertainment, which operated the venue during its first year. Under th

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Oct 19 • 10:04 AM EDT • Health • youarecurrent.com
Alice Ruppert on the Science and Art of Video Game Horses

Interviewing Alice Ruppert about horse anatomy, narratives, and more! Interview by Jahanzeb Khan.

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Oct 19 • 10:00 AM EDT • Science • superjumpmagazine.com
1.7K views · 25 reactions | ON-ORBIT SCIENCE🔬 Astronaut Anil Menon...

ON-ORBIT SCIENCE🔬 Astronaut Anil Menon welcomed the arrival of a SpaceX cargo capsule at the International Space Station as the crew kicks off a "busy season of science." Menon said they are...

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Oct 19 • 9:50 AM EDT • Science • facebook.com
Manchester United stars claim interview ban after Lisandro Martínez outburst

Manchester United players Bruno Fernandes and Matheus Cunha claimed they were not allowed to speak to reporters after their 1-1 draw at Leeds United in the wake of Lisandro Martínez's TV outburst

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Oct 19 • 9:46 AM EDT • Sports • sports.yahoo.com
Supreme Court backs Pentagon decision to throw out plea deals for 9/11 alleged conspirators

The Supreme Court on Monday declined to review former Defense Secretary Lloyd Austin’s decision to cancel plea agreements with Khalid Sheikh Mohammed and two other defendants accused of plotting the 9/11 terror attack.

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Oct 19 • 9:37 AM EDT • Politics • cnn.com
Judicial Dialogues on Health and Climate Change: An Interview With Alicia Ely Yamin - Petrie-Flom Center

How can courts respond to the health impacts of climate change? On the occasion of a conference at Harvard Law School on 29 October 2026, sponsored by the Walter de Gruyter Foundation, we spoke with one of its conveners, Alicia Ely Yamin, about the right to health, climate change, and the role of judicial enforcement.

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Oct 19 • 9:30 AM EDT • Health • petrieflom.law.harvard.edu
Politicization of science is leading American researchers to foreign universities

More than a year after the Trump administration began making seismic changes to U.S. scientific research, many American scientists are being recruited by foreign universities offering stable funding and academic

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Oct 19 • 9:10 AM EDT • Science • shorelinemedia.net
Accenture is looking to sell Greater China business for up to $1.5 billion, FT report says

The FT report says Accenture hired JPMorgan to review the unit after unsolicited interest over the past year

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Oct 19 • 8:44 AM EDT • Business • qz.com
Agassi Sports Entertainment Converts $1M Note, Raises $1.5M From Andre Agassi Affiliate at $5 Units

Agassi Sports Entertainment executed multiple financing actions, converting a $1,000,000 insider note into equity and warrants and raising $1,500,000 in a new unit purchase by Investments AKA at $5.00 per unit. The conversion yielded 200,000 common shares and 200,000 three-year cash-only warrants w…

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Oct 19 • 8:33 AM EDT • Entertainment • tradingview.com
Nobody should buy the $299 Apple TV 4K, but it could have been worse

My colleague Zac Hall described HomeView as one of the best ways to spend $299 on an Apple device and...

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Oct 19 • 8:11 AM EDT • Technology • 9to5mac.com
Professional golfer from Finland moves business to Fairview

A golf professional who hails from Finland and moved his business to Fairview approaches teaching the sport differently. For Jari Hakonen, it is all about focusing on the little things […]

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Oct 19 • 8:00 AM EDT • Business • theoutlookonline.com
Professional golfer from Finland moves business to Fairview

A golf professional who hails from Finland and moved his business to Fairview approaches teaching the sport differently. For Jari Hakonen, it is all about focusing on the little things […]

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Oct 19 • 8:00 AM EDT • Business • estacadanews.com
Even Realities G2 review: Smart glasses, stupid controls

Even Realities makes one of the best smart glasses on the market, but controlling its growing feature set is harder than it should be.

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Oct 19 • 7:30 AM EDT • Technology • engadget.com
DOJ Revives Business Review Letters, Then Withdraws One

The DOJ relaunched its business review letter program, letting companies seek advance views on proposed conduct. The guidance is narrow, public, nonbinding, and can become outdated as facts or markets change. Companies must disclose substantial information, and the DOJ may decline to respond—so the program offers some guidance, but not immunity or certainty.

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Oct 19 • 7:00 AM EDT • Business • law.com
Experts say your health insurance should cover gym memberships to prevent cancer from coming back. Why don't they?

Fitness programs are increasingly viewed as good cancer fighters, but insurers limit the coverage.

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Oct 19 • 6:45 AM EDT • Health • finance.yahoo.com
Pregnant Ten-Year-Old Girls Cannot Be a Political Talking Point

Taking a pause in the heat of the midterms to check on the health of children.

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Oct 19 • 6:30 AM EDT • Politics • nationalreview.com
Lead with gut health substantiation, not speculation at SupplySide Global

From digestive comfort to immune health and mental wellbeing, discover how Bimuno GOS supports targeted product innovation. Visit booth 4249 at SupplySide Global to explore the science

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Oct 19 • 6:18 AM EDT • Health • nutraceuticalbusinessreview.com
JD Bertrand recalls mentorship from Chiefs LB Drue Tranquill

During his interview with @EdEastonJr, Atlanta Falcons linebacker JD Bertrand recalled mentorship from Kansas City Chiefs linebacker Drue Tranquill

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Oct 19 • 6:00 AM EDT • Sports • sports.yahoo.com
Best Bill Pay Software for Small Business (2026): Melio Selected by Better Business Advice for Streamlining Vendor Payments

Better Business Advice has published a new review of bill pay software for small businesses, selecting Melio for streamlining vendor payments through a centralized accounts payable workflow.

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Oct 19 • 6:00 AM EDT • Business • finance.yahoo.com
West Village bars, restaurants face city scrutiny over zoning, licenses at council member’s request

A Detroit City Councilmember is pushing for a review of a handful of businesses.

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Oct 19 • 5:45 AM EDT • Business • crainsdetroit.com
Gateway Health Alliances to discuss GLP-1 product innovation at SupplySide Global

The US botanical ingredient supplier will be exploring weight management, metabolic health and nutritional support for consumers discontinuing GLP-1 medications at this year's show

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Oct 19 • 5:03 AM EDT • Health • nutraceuticalbusinessreview.com
Governor Greg Abbott doesn't believe the polls and says Texans will put him in office for a fourth term

In an interview with Lone Star Politics, Republican Texas Governor Greg Abbott makes a lot of news. He commits to tough new data center laws next session. He explains why he doesn’t want to debate his opponent in November, State lawmaker Gina Hinojosa. And he lays out his priorities if elected once again.

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Oct 19 • 5:03 AM EDT • Politics • nbcdfw.com
Inside a Republican’s business safety record, under scrutiny in key House race

Public records and interviews with ex-workers shed light on a company run by John Braun, who is challenging Rep. Marie Gluesenkamp Perez (D-Washington).

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Oct 19 • 5:00 AM EDT • Business • washingtonpost.com
Market Open: Primary Health Properties JV, Serica Growth

FTSE 100 and European stocks decline as Primary Health Properties announces a £700m joint venture, Serica reports growth and Brent crude weakens. Market OverviewThe FTSE 100 opened lower on Monday, falling 0.

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Oct 19 • 4:45 AM EDT • Health • uk.finance.yahoo.com
Imagicaaworld sells hotel, acquires water park stake, eyes indoor entertainment push

Imagicaaworld Entertainment Limited on Monday disclosed a clutch of strategic moves, including the sale of its hotel asset and a new park acquisition, as it reported a 6 per cent dip in visitor footfalls for the July-September quarter of FY27.The Mumbai-listed amusement and water park operator said…

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Oct 19 • 4:19 AM EDT • Entertainment • tradingview.com
🗞️ Today's front pages: Madrid's controversial win, Barça-PSG preview

After a weekend of truly thrilling matches, a new week packed with news begins. So let's take a look at the front pages of the sports newspapers...***MARCAASSPORTMundo DeportivoSuperdeporteEstadio De...

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Oct 19 • 3:01 AM EDT • Sports • sports.yahoo.com
Novichok Nerve Agents: What Science Actually Knows About the Deadliest Weapons

A new review finds that while Novichok agents potently inhibit acetylcholinesterase and modern forensics can verify exposure, many claimed properties of these weapons remain unvalidated by experiments on authenticated compounds.

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Oct 19 • 1:22 AM EDT • Science • bioengineer.org
Weekly Recap: Open-science AV partnership and benchmark performance pledge

Valeo SE (EURONEXT:FR) is partnering with KE:SAI to co-develop an open-science autonomous driving system for general vehicles, aiming to match and surpass major public driving benchmarks while committing to reproducible AI research and openly publishing results.Previous Week RecapThis is an AI-gene…

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Oct 19 • 1:00 AM EDT • Science • tradingview.com
A modernized health plan: Supporting cost management and the employee experience.

The Surest health plan puts prices and care options in plain view. When costs are visible ahead of time, members may choose differently. And those choices have a ripple effect: potentially reducing costs for both members and employers. Win-win.

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Oct 19 • 12:01 AM EDT • Health • mainebiz.biz
Sudoku

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Oct 19 • 12:00 AM EDT • Entertainment • thederrick.com
Trained community volunteers to monitor seagrass for study

The research is geared toward finding the best ways to train community volunteers to collect data on underwater seagrasses in waters throughout the state in a program led by Coastal Carolina Riverwatch and the University of North Carolina Wilmington and funded by North Carolina Sea Grant.

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Oct 19 • 12:00 AM EDT • Science • coastalreview.org
Garfield

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Oct 19 • 12:00 AM EDT • Entertainment • thederrick.com
Peanuts

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Oct 19 • 12:00 AM EDT • Entertainment • thederrick.com
‘Other Desert Cities’ Broadway review: A-listers take family dysfunction to another level

Julia Louis-Dreyfus and Ed Harris star in the ‘Other Desert Cities’ revival on Broadway, with the ‘Seinfeld’ star making a triumphant debut. Read EW’s review.

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Oct 19 • 12:00 AM EDT • Entertainment • ew.com
NBCUniversal’s shoppable TV business is seeing a boost from shows like ‘Traitors’ and ‘Love Island USA’

Viewers can now buy products from about 12 of their favorite NBCUniversal shows, including "Top Chef" and "Below Deck."

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Oct 19 • 12:00 AM EDT • Business • modernretail.co
Her Health, Her Future holds rally in support of Amendment 3

Her Health, Her Future shares support of Amendment 3 in Jefferson City late Sunday afternoon.

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Oct 18 • 10:00 PM EDT • Health • komu.com
Old Fidel Castro interview resurfaces in attack ad against Miami congresswoman

“She cozied up to a dictator and, now, she is cozying up to another wanna be dictator, Donald Trump,” Eliott Rodriguez said in the ad.

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Oct 18 • 7:11 PM EDT • Politics • miamiherald.com
Marshmallow Root’s Chemistry Revealed: The Science Behind an Ancient Cough Remedy

A new review in Pharmacia compiles the chemical compounds and pharmacological effects of Althaea officinalis, the marshmallow plant long used for coughs, wounds, and inflammation.

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Oct 18 • 6:07 PM EDT • Science • bioengineer.org
Trust In Science Falls Fastest Among Those Left Behind

Poor access to healthcare, limited local influence over research priorities, and an unequal distribution of scientific benefits are undermining public

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Oct 18 • 5:06 PM EDT • Science • eurasiareview.com
Samsung Galaxy Z Fold 8: 7 ways to make the most of its wider foldable design

Here are seven ways to make the most of the Samsung Galaxy Z Fold 8’s wider design, from multitasking and photography to entertainment and hands-free viewing.

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Oct 18 • 4:26 PM EDT • Technology • gizmochina.com
Streaming’s Biggest Show Returns…and a Buzzy Genre Struggles

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Obviously, the big news of the week (if not month) is Netflix letting go of executive Bela Bajaria, their chief content officer. I’m going to cover this in my next “Most Important Story of the Week”, but I also have a data angle that I might publish before then. (Too much news this month, am I right?) But first, I have a bonus Streaming Ratings Report issue for you. Today’s article is a bit of a grab bag of topics I’ve wanted to write about, but couldn’t squeeze into the (already very long) Streaming Ratings Report issues. The NFL drives huge viewership numbers, so I’ve got a look at that. A whole bunch of TV shows returned to the traditional broadcast channels, and I have thoughts. And I have a quick look at adult animated shows, since a couple flopped earlier this month. Plus, the Emmys aired earlier this month, and we got some fun data bout how popular those nominated shows are and why I’m not optimistic about the show’s future. That’s a lot, so let’s dive right in. Subscribe Sports - Football Remains the King of Streaming Over the last two Streaming Ratings Reports, I sorta ignored the biggest “show” each week. (I was tempted to say “piece of content” but I know that word bugs folks.) In my database, I call these “specials”, and they sure are special. I speak of the king of American TV: football!!! Streaming football is back and, unlike some other sports, it routinely dominates all viewership. Probably the best way to show this is to update one of my favorite graphics, the “40 Million Hour Club”1 since football games have joined that club each week they’ve premiered: (Yep, that’s the data through 28-Sep, the first four weeks of the season. As a reminder, I take the average minute audience provided by Nielsen, factor out a percentage of linear TV viewers in home markets, and multiply the run time by the three-hour runtime.) Again, the numbers are huge. Let’s start with Netflix. They grabbed the rights to the bonus opening week NFL Kickoff game (which was on YouTube last year) and it put up 18.5 million viewers on average. That nets out to 47.4 million hours of estimated streaming hours. That’s good! Though, notably, it’s well below Christmas Day games from previous years. Compared to other streamers/broadcasters, that’s a bit of a mixed result. On one hand, Netflix’s 18.5 million average is about what YouTube claimed last year, though Nielsen used a bespoke methodology at that time, so I trust this viewership figure more. So that’s good. (The game also shifted from a Friday to a Thursday and that could have helped the viewership as well.) And Netflix continues to best Prime Video in total viewership—as you’ll see next—though Netflix has had much higher-profile (opening week and Christmas Day) games. NBC/Peacock’s opening game the night before averaged 25.1 million average viewers, which is just much bigger than Netflix (or Prime Video). That’s the big caveat to all streaming viewership records: even in success, they can’t compete with traditional linear TV. Previously, I called this my “hierarchy of viewership”, and the data keeps supporting that thesis. The downside for NBC is that this game’s viewership was down compared to previous years, though it may be a counting issue. Here’s a great chart from Sports Media Watch: Indeed, looking at all the opening week games across all windows, Netflix still lags the other primetime windows, but does well compared to the afternoon games: I saw a few folks make the case that streamers still lag traditional broadcasters in reach, and I’d add they really lag compared to “broadcast plus streaming” options like NBC/Peacock, ESPN/Disney+ and CBS/Paramount+. The best data I saw for this came from Samba TV, who charted reach through the 2025 season, and, wow. (Samba TV’s numbers are historically lower than Nielsen’s, so don’t compare their household figures to Nielsen’s hours, but use them as a proxy for the relative reach of the streamers.) The good news is Prime Video is NOT having a down year. Their opening Thursday Night Football game reached 18.6 million viewers (about what Netflix got), but that’s a high for Prime Video on Thursdays and the biggest Thursday night game since 2015. The TNF games the weeks of 21-Sep and 28-Sep continued this streak, getting 43.1 (16.8 million average viewers) and 42.5 total hours (16.6 million average viewers), which were both up from last year. Still, that continues the (typical) season slide: (For those new-to-streaming-football-numbers folks, the viewership declines for Thursday Night Football as the year goes along.) Overall, it appears as if Prime Video is now part of the “football habit”, be it for customers at home or out at places like bars and restaurants. And its viewership is slowly catching up to broadcast. One last chart shows this. Last season, Nielsen started adding out-of-home viewership to the charts, so I try not to do season-to-season comparisons as I did for the first few years. And while Nielsen added Big Data viewing this year, I’m going to compare the last two seasons. Here’s that chart, which shows the season-over-season gains: When it comes to streaming football, we have to keep a few seemingly contradictory thoughts in our head… First, streaming doesn’t come close to matching broadcast’s reach and, thus, viewership. Second, even with that gap, football is still the biggest “thing” on streaming. It’s very, very popular. Third, while some methodology changes have likely helped Prime Video’s numbers, their viewership does appear to be growing. Lastly, yeah, the NFL started the season off poorly, with week one dragging down the numbers in year-over-year comparisons. However—and again, methodology changes may have helped this—the viewership grew compared to previous seasons over the next couple of weeks. So football is still king. On streaming and off. Television - Adult Animation Continues to NOT Make the Streaming Charts In the last two reports, two adult-animated shows whiffed: Netflix’s animated comedy, Dang! Paramount+’s Sega-video-game-inspired fantasy/comedy, Golden Axe. Neither made the charts, but that’s usually the case for animated shows. I mean, here’s literally every animated show that’s made the Nielsen Original charts since the start of 2025: And one of those shows is G_abby’s Dollhouse_! A kids show! The problem with charts like this is that they don’t give you a sense of how many shows miss the charts. Netflix had at least eleven animated flops, including comedies like Big Mouth (a show everyone assumed was popular in the pre-Streaming Ratings Era), Long Story Short, Haunted Hotel, Mating Season, Strip Law, and Alley Cats, and action shows like Blood of Zeus, Castlevania: Nocturne, Devil May Cry, Splinter Cell: Deathwatch, and Tomb Raider: The Legend of Lara Croft. Prime Video had at least six animated misses, two in the same universe (Hazbin Hotel, Helluva Boss), three more comedies (#1 Happy Family USA, The Second Best Hospital in the Galaxy and Kevin) and an action show (The Mighty Nein). Disney+ had MCU and Star Wars animated misses (Eyes of Wakanda, Marvel Zombies, Star Wars: Visions, Star Wars: Maul – Shadow Lord, and Star Wars: Tales of the Underworld) but I can’t tell how many of those shows were geared towards adults. HBO Max had Harley Quinn and Hulu had Solar Opposites. None of these shows made the charts! That’s a lot of misses! If I remade the chart with all those misses, here’s how it would look: Listen, I know the counter arguments. First, it’s cheaper to produce animated shows than live action. Fair enough, but with viewership this low, even that cheaper price point starts to not matter. Second, just look at the acquired charts. Hit animated comedies can generate viewership for years! Shows like The Simpsons, South Park, Family Guy, and Bob’s Burgers do really, really well. Fair enough, but streaming has failed to recreate the dynamic that Fox has mastered so well. That’s a problem for streaming still. Television - Emmys! The annual Emmys broadcast was a few weeks ago, and I’ve got data on how the nominees performed on streaming, plus hot takes on this year’s viewership (and the big news about the broadcast’s, er, streamcast’s future). We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… The top Emmy-nominated shows… ...why I’m worried about the future of the Emmys telecast... ...the pros of broadcast television ...and the cons... ...please subscribe! We can only keep doing this great work with your support. Coming Soon! Next week, we’ve got a double issue (since the weeks of 21-Sep and 28-Sep were so light), but then I’ll be all caught up after a deluge of streaming ratings data from Nielsen in September. In the meantime, I’m going to try to take a look at Netflix’s stats to explain why Bela Bajaria is out. But even light weeks give me plenty to talk about. The Great British Baking Show returns to Netflix and Apple TV has a buzzy new star-studded comedy. And Netflix has a controversial-but-appears-to-be-popular new game show. Plus big films like Toy Story 5, Backrooms and The Breadwinner head to streaming. And is East of Eden a hit? After that, The Kardashians return to Hulu, Prime Video has a reboot of Carrie, and Netflix has a horror show, Below. Disclosure Day heads to Peacock, The Housemaid heads to HBO Max_,_ a new Ben Affleck film, Animals, lands on Netflix, and Apple TV has a new John Cena action film based on, checks notes, Hasbro’s Matchbox toys. Okay. Longterm, some interesting TV production news. HBO Max ordered How to Survive Without Me, starring Kaley Cuoco, Joshua Jackson, Ray Romano and Rita Wilson, for fifteen episodes! I love that some streamers (or, at least, HBO Max) are finally ordering TV shows with more than eight episodes. In less wise production news, Landman does not appear to be coming back this year, since it just started production. Frankly, I don’t love this (get your shows out on time) but Landman is so popular, I doubt it matters.

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Oct 18 • 3:59 PM EDT • Entertainment • entertainment.substack.com
Michael Carbonaro reflects on path to becoming a professional magician

The longtime magician will visit the Payne & Mencias Palladium on Oct. 23.

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Oct 18 • 3:10 PM EDT • Entertainment • nuvo.net
Capitol View: Analysis of Talk Business & Politics-Hendrix College poll

It’s been a busy week of polling as Arkansas took a focused approach to the November midterm elections ahead.

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Oct 18 • 2:43 PM EDT • Business • kark.com
Capitol View: Analysis of Talk Business & Politics-Hendrix College poll

It’s been a busy week of polling as Arkansas took a focused approach to the November midterm elections ahead.

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Oct 18 • 2:43 PM EDT • Politics • kark.com
Apple Expected to Release New Products on Next Four Fridays

Apple likely plans to release MacBook Pro models with OLED displays, 14-inch MacBook Pro and iMac models with M6 chips, and/or an iPad mini 8 with an OLED display on Friday, November 6, according to Bloomberg's Mark Gurman. The devices are expected to be announced on Tuesday, October 27 or Wednesday, October 28. If this timeframe proves to be accurate, then Apple will be releasing new products for the next four Fridays, with the other dates already announced.

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Oct 18 • 2:01 PM EDT • Technology • macrumors.com
Apple's HomeViews Reportedly Collected Dust in Warehouses 'For the Better Part of a Year'

The product pipeline was choked nearly to death by Siri delays.

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Oct 18 • 1:46 PM EDT • Technology • gizmodo.com
Sizzle Dining exceeds 100,000-meal goal in milestone 10th year

Sizzle Dining, Southwest Florida's premier culinary fundraiser, surpassed its ambitious goal of selling 100,000 meals during its monthlong dining event, generating a record $105,655 donation for Blessings in a Backpack

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Oct 18 • 1:00 PM EDT • Entertainment • floridaweekly.com