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MLB suspends Red Sox's Willson Contreras, Nationals pitcher Cade Cavalli, others after benches-clearing incident
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Jul 2 • 5:38 PM EDT • Sports • sports.yahoo.com
Cavs announce 2026 NBA Summer League roster

Nae’Qwan Tomlin will be joining the group heading to Vegas.

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Jul 2 • 4:00 PM EDT • Sports • sports.yahoo.com
WATCH: U.S. Attorney Jeanine Pirro announces felony charge related to Reflecting Pool

A former Olympian was indicted Thursday on a felony charge in what President Donald Trump has called vandalism of the Reflecting Pool.

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Jul 2 • 3:43 PM EDT • Politics • pbs.org
Chiefs Continue To Pump Out Positive Health Reports On Mahomes As Camp Approaches
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Jul 2 • 2:49 PM EDT • Health • sports.yahoo.com
Inside Bask Health: The Plug-and-Play Infrastructure Supporting the Telehealth Boom

Bask operates behind the scenes of the Direct-to-Consumer (DTC) telehealth market, providing infrastructure that aims to streamline the backend process.

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Jul 2 • 1:13 PM EDT • Health • usatoday.com
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2026 Phillies MLB Draft Preview: Caden Sorrell, OF

Just as I was trying to figure out who to write up next, Baseball America popped out their 5th mock draft, this time with a new name as the Phillies pick. It doesn’t sound like there’s sourcing for this or actual rumors of Phillies interest so much as there is “It’s the 36th pick. Who […]

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Jul 2 • 1:00 PM EDT • Sports • sports.yahoo.com
2026 NASCAR Odds: Denny Hamlin Favored As Cup Returns To Chicagoland Speedway

The NASCAR Cup Series is heading back to Chicagoland Speedeway for the first time since 2019. Here are the latest odds for the eero 400.

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Jul 2 • 12:14 PM EDT • Sports • foxsports.com
Heat Wave Caused Some 480 Excess Deaths in Netherlands, Health Authorities Say

AMSTERDAM, July 2 (Reuters) - ⁠Last ⁠week's unprecedented ⁠heat wave led to around 480 excess deaths in ‌the Netherlands, Dutch health ‌authorities said ⁠on ⁠Thursday. • Excess deaths in the week from June 22 to 28 were mainly among people aged 80 years and older. • Most ⁠were reported ⁠in the ...

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Jul 2 • 10:32 AM EDT • Health • usnews.com
MLB Predictions and Moneyline Picks for Thursday, July 2

Colby Marchio’s MLB moneyline leans and insights for Thursday, July 2, featuring the Los Angeles Angels.

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Jul 2 • 10:21 AM EDT • Sports • sports.yahoo.com
MOMENT OF SCIENCE: Two planets lighter than cotton candy

Astronomers have discovered two planets the size of Jupiter, but get this: their densities are so low, they’re estimated to be lighter than cotton candy!

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Jul 2 • 9:32 AM EDT • Science • wistv.com
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City Hall visit, packed entertainment slate highlight 2026 HBCU Swingman Classic schedule

Major League Baseball today announced the pregame and philanthropic details for the 2026 HBCU Swingman Classic presented by USA Baseball, highlighted by a team visit to City Hall, Philadelphia Mayor Cherelle L. Parker’s first pitch, uniform patches honoring HBCU legend Roger Cador and pregame entertainment by Grammy-Award winner Durand Bernarr

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Jul 2 • 9:09 AM EDT • Entertainment • mlb.com
Bonus 236: A Term of Self-Inflicted Wounds

Within minutes of the Supreme Court handing down the birthright citizenship ruling on Tuesday and rising for its summer recess, its defenders were pointing to that decision (alongside the late-arriving mail-in ballots ruling on Monday and the tariffs ruling from February) as decisive proof that the Court really is “above politics,” and that criticisms of the justices for behaving more like politicians in robes than like judges are thus unfair. For a particularly thoughtful version of this claim, see Professor Will Baude’s opening response to the latest New York Times written roundtable about the Court with Baude, Professor Kate Shaw, and me. In that roundtable, I already offered one of the two major arguments against this thesis—that it’s an assessment of the numerator without regard to the denominator, and that a full account of the Court’s behavior throughout OT2025 suggests that the Court behaved even more politically during the current term than during even the previous (highly politicized) one. Just to take one of many data points, last term (OT2024), there were six rulings in argued cases in which all six Republican-appointed justices were in the majority and all three of the Democratic appointees were in dissent (along with a slew of such rulings on the emergency docket). This term, there were … 13. (Along with two 6-3 summary reversals and 10 rulings on the emergency docket from which the three Democratic appointees all dissented.) Today’s bonus issue addresses the flip side of that coin. In particular, below the fold, I identify four different moments in which the justices could have acted in ways to specifically defuse charges of political behavior—and opted instead to lean all the way in. As much as end-of-term narratives focus on what the Court did, and on the takeaways from individual rulings, consider today’s post an attempt to identify opportunities that the Court missed, as well. At least in the examples discussed below, by opting for the outcome that made the Court look more transparently political, the Court inflicted a series of (unnecessary) credibility wounds on itself. For those who aren’t paid subscribers, we’ll be back Monday with our regular coverage of the Court. For those who are, please read on.

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Jul 2 • 7:15 AM EDT • Politics • stevevladeck.com
USMNT proves it’s built different with first World Cup knockout win in 24 years
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Jul 2 • 1:56 AM EDT • Sports • sports.yahoo.com
Cincinnati Reds middle infielder Matt McLain on playing centerfield

Cincinnati Reds 2B/SS Matt McLain made his first career MLB start in centerfield Wednesday night in Milwaukee.

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Jul 1 • 7:52 PM EDT • Sports • sports.yahoo.com
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MLB Players Propose Limiting Optional Assignments To Minor Leagues, More

MLB players proposed that optional assignments to the minor leagues be cut from a maximum of five per season to three.

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Jul 1 • 3:58 PM EDT • Sports • foxsports.com
Haleon teams up with Microsoft in 5-year AI pact to upgrade consumer health operations

Consumer health giant Haleon has tapped Microsoft to incorporate AI across its operations, joining a growing wave of healthcare and life sciences heavyweights turning to Big Tech to execute enterpr | Consumer health giant Haleon has tapped Microsoft to incorporate AI across its operations, joining a growing wave of healthcare and life sciences heavyweights turning to Big Tech to execute enterprise-wide digital overhauls.

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Jul 1 • 10:14 AM EDT • Health • fiercepharma.com
Gift From Phil Hochberg ’61 Combines His Passion for Newhouse, Sports and DC

A prominent lawyer, Phil Hochberg is also well-known in Washington, D.C., as a former MLB, NFL and college public address announcer.

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Jul 1 • 10:01 AM EDT • Sports • newhouse.syracuse.edu
Orlando City SC Signs Strategic Partnership with Football Science Institute

Lions and FSI to collaborate on integrating scientific knowledge with professional practice, research and development

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Jul 1 • 9:59 AM EDT • Science • orlandocitysc.com
Sony will cease production of discs for new PlayStation games in 2028

New games sold for PlayStation consoles will only be available digitally and won’t be sold on discs effective January 2028, Sony has announced. The move applies to all PlayStation games released from that point on, including those made by Sony and those released by third parties. The PlayStation group calls the change “a natural direction for Sony Interactive Entertainment to adapt to consumer trends as the general preference for digital media significantly outpaces physical discs,” according to a PlayStation blog post reviewed by Game File in advance of its publication. As movies, TV and music have shifted from physical media to an age of downloads and streaming, Sony’s move could speed the demise of physical media in a gaming. The industry has offered consumers games via cartridges, cassettes, floppy discs, CDs, DVDs and Blu-Rays across a 50-year stretch. Sony has been reporting to investors in recent years that PlayStation games have been increasingly purchased as downloads, not as discs. The most recent figures show nearly four in five purchases of full games for PlayStation 4 and PlayStation 5 were purchased digitally in the past year. Stats like that may cause today’s news to carry an air of the inevitable. But Sony’s declaration for 2028 is still likely to produce a shock, as the biggest gaming platform on the planet that uses game discs leaves them behind. Discs going away, but the fate of game boxes is unknown Sony is committing to still selling games in physical retailers even after they drop discs in 2028. Just how those games will be sold—in boxes with codes inside, as cards marked with digital redemption codes—is unclear. Digital games will also continue to be sold in the online PlayStation Store. New games released for PlayStation consoles prior to January 2028 will be unaffected by the policy change, Sony says. That means the PS5 games of 2027, be they a new Madden, a new God of War, a new Call of Duty, a new Sly Cooper (one can dream?), would still potentially be offered on disc. PlayStation 6 implications Sony’s timeline for a transition to a no-disc era will also spin up more speculation about the timing and configuration of Sony’s next-generation console, the probable PlayStation 6. “This pretty much guarantees that PS6 won’t arrive until 2028 at the earliest,” Piers Harding-Rolls, senior games research analyst at Ampere Analysis tells Game File. Harding-Rolls also concludes from today’s news that “the base version of a PS6 will not include a physical media drive,” as Sony looks to keep costs down on the device. Sony itself is saying nothing about the PS6 today: not its timing, nor how it might or might not support internal or external disc drives in order to run disc-based PS4 and PS5 games, should the console be backwards compatible. The many signs this was coming Industry support for games being released on physical media has been waning. As has consumer interest in them. PC games effectively went all-digital years ago, thanks to the popularity of playing games through Steam and other digital storefronts. The Covid-19 pandemic and the lockdowns that kept much of the global population home helped shift shopping patterns toward downloads. Sony’s own data shows PlayStation game downloads being an uncommon consumer choice a decade ago and now becoming the norm. On consoles, physical media has been in such decline that Sony and Microsoft both launched their current gen Xbox Series and PS5 consoles in 2020 with cheaper versions that lacked disc drives. In early 2024, Phil Spencer, then head of Xbox, told me that ““[w]e ship games physically and digitally, and we’re really just following what the customers are doing.” He added that the game industry had become an outlier in still supporting disc-based entertainment, even as movies and TV have bailed on discs in favor of downloads and steaming: “Gaming consoles themselves have kind of become the last consumer electronic device that has a drive. And this is a real issue, just in terms of the number of manufacturers that are actually building drives and the cost associated with those. And when you think about cogs that we’re going to go put in a console—and as you have fewer suppliers and fewer buyers—the cost of the drive does have an impact.” Last year, the Nintendo’s Switch 2, which uses cartridges rather than discs, introduced the concept of game-key cards, which are physical media that contain no game, just a prompt for a download. Even disc-based games aren’t what they once were, now frequently containing just stubs of games rather than the whole thing. The website Does It Play has tested over 3000 games and found that, for example, that the disc version of this year’s hit 007: First Light, only contained the game’s first mission, with the rest needing to be downloaded. Beyond all that, last week brought the news that Grand Theft Auto VI, likely the biggest game launch this decade, will debut for PS5 and Xbox Series without a disc-based version. Today’s big news comes to you for free. Game File is a reader-supported publication. To receive new posts and ensure more of my work is possible, please consider becoming a free or paid subscriber. Subscribe Discs helped define PlayStation However the trends in entertainment may be going, it is still remarkable to see PlayStation ditch discs given their importance in PlayStation history: In the late 1990s, the first PlayStation’s support for games on relatively cheap CD-ROMs instead of traditional game cartridges allowed the upstart console to outmaneuver cartridge-based systems from Nintendo and Sega, as it drove down game prices down in the process. (The cheaper disc format even prompted Final Fantasy VII maker Square to taunt Nintendo in a magazine ad, saying that if the game was “available on cartridge, it’d retail for around $1200.”) PlayStation devices often doubled as machines for watching movies and TV on the latest disc-based formats. In the late 2000s, for example, Sony’s pricy PS3 gained traction as a go-to device for playing then-novel Blu-Ray discs. In 2013, Sony effectively roasted the digital game-sharing restrictions proposed by rival Microsoft for its upcoming Xbox One console by showing how games could be shared for the then-upcoming PS4. In a 21-second clip that has over 20 million views on YouTube, one PlayStation executive simply handed a game box—presumably with disc inside—to another, who said “thanks.” Sony’s possible motivations The PlayStation announcement today cites “consumer preferences” and a shift away from discs among “the broader entertainment industry,” but does not delve into the decision-making process that brought Sony to this point. Sony is not discussing the economics of this move (I asked!), but there are a number of potential factors: Abandoning discs will spare Sony the cost of manufacturing and shipping them, which analysts and industry veterans I spoke to said could account for $1 or so of a game’s retail price. For first-party games, that’s direct savings for Sony, though the amount is limited by the winnowing percentage of people who were even buying the disc-based versions. For third-party games, Sony could pass the savings on to partners or just retain the better profit margin for themselves. As the 2024 comments from Phil Spencer alluded to, leaving discs behind could mean leaving disc-drives behind, allowing Sony to produce consoles more cheaply. Switching to digital-only for games could diminish the risks of copies of new games leaking. It would also seemingly make second-hand sales of used games impossible, pushing more people to buy their own copies of games. These economic benefits for Sony could be boons for the games industry overall, Ampere analyst Piers Harding-Rolls tells Game File. Among other things, it could free publishers and retailers from having to worry about securing an inventory of game discs when trying to sell games, he noted. “If there is a way to streamline the business of games retail, I generally think it’s a good thing for the industry as it removes unnecessary costs,” Harding-Rolls said. “This will help offset pressure on margins from other directions – development and staffing costs for example.” Should the industry shift from game boxes that contain discs to smaller, cheaper game cards, Harding-Rolls said, that reduces pressure on publishers and retailers. “The advantage of everything going digital for the industry is that sales can be tracked much more easily and there is less commercial risk for publishers wanting to continue selling via retail,” he said. The shift to no discs will also likely impact game development timelines, as developers will no longer face the same urgency to have a build ready to submit to PlayStation for the production of a disc, as industry experts noted around GTA VI’s no-disc news last week. Instead, projects may gain weeks of development time, in the event delivery deadlines for platform approval move closer to release date. Preservationists’ likely worries While millions of gamers have shifted to digital, there are still people who associate game discs—and only game discs—with actual ownership of PlayStation games. That portion of the gaming community spoke up last week about wanting to buy a version of GTA VI that they could hold in their hands, could lend to a friend and could potentially pop into a well-preserved PS5 console three decades from now and still see it run. Such gamers didn’t want to worry that they’d merely purchased a digital copy that could lose access to the game if, say, the company behind the game someday turns of the servers that transmit downloadable copies. Digital copies of games are inherently less long-lasting, because consumers aren’t actually buying a game (on a disc), just buying access to the game. The fine print in online gaming shops notes this, as does a recent law that went on the books in California in 2025. That lasw requires game publishers doing business in the state to refrain from words like “sell” when offering digital copies of games, unless they explicitly tell consumers that what’s being sold isn’t the game itself but a potentially revocable license to access it. A Sony spokesperson noted to Game File that “[w]ith all digital content, including games, movies, and music, players are purchasing a personal license for non-commercial use.” Regarding the fears of PlayStation games being lost to time in an all-digital era, the rep also noted that Sony remains “committed to delivering experiences from past generations to the new platforms our players are using.” They noted that PlayStation has used emulation and remasters to keep offering its classic games to modern gamers. It’s true that many consumers have become accustomed to not having physical copies of new music albums or movies, but the relative precariousness of digital copies of games is in fact being highlighted today by…. Sony’s other big announcement: the upcoming closure of the PS3 and PS Vita online stores Sony said today that it will be closing the online marketplaces for its PlayStation 3 console and PS Vita handheld in most countries in July 2027 (sooner elsewhere: August 2026 for the PS3 store Mexico, Honduras and Nicaragua; late 2026 for PS3 in other Latin American countries and the Middle East). “We know this news may be disappointing to PS3 and PS Vita players who hold a special place in their hearts for this generation of gaming,” Sony said in its announcement, saying the move “was not an easy decision for us to make.” Sony said that PS3 and Vita marketplaces “are no longer able” to support modern commerce systems, prompting a “need” to close the shops and focus on more modern PlayStation platform stores. The news may spark some deja vu. Sony announced back in March 2021 that it planned to take the PS3, Vita and PlayStation Portable marketplaces offline that summer. The move would have caused some 2,000 digital-only games to become unavailable for new purchasers, according to a VGC analysis at the time. Fans complained loudly. By April 2021, Sony walked back the PS3 and Vita shop closures, with then PlayStation boss Jim Ryan saying “it’s clear that we made the wrong decision here.” This time around, Sony is giving a longer notice period in most regions. The closure of those stores is still likely to cut off access to new purchases of digital-only PS3 and Vita games. The current PlayStation 5 marketplace sells PS5 and PS4 games, as well as a selection of PS1 and PS2 games. It does not sell PS3 games, because games for that platform can’t run on the system (some are offered via a PlayStation Plus streaming option). Vita games also aren’t sold via PS5. Sony says digitally purchased PS3 and Vita games will be downloadable after the stores’ shutdowns “for the foreseeable future.” Sony’s move contrasts with Microsoft’s Xbox platform, which continues to sell and support games from all four Xbox console generations. But it puts it in line with Nintendo, which disabled purchases in the marketplace for its Wii console (a contemporary of the PS3) in 2019. Nintendo discontinued purchases in the online shop for its 3DS portable (a contemporary of the Vita) in 2023. The big questions about Sony’s 2028 post-disc era Will Microsoft follow suit, ending support for new disc-based games on Xbox platforms and therefore all game consoles, too? Whether Microsoft does or not, will third-parties that can no longer release games on discs for PlayStation, simply ditch the disc options across the board? Given the GTA VI no-disc experiment launching this November, will more game publishers decide to forgo disc-based offerings even in 2027? How will no-disc PS5/6 games be packaged and sold in brick-and-mortar retail stores? What becomes of game sharing in an all-digital era? Will Sony modify its current set-up, which currently allows some sharing of digital games across a pair of consoles, to allow more casual lending? (See for example, Nintendo’s year-old system of letting players lend a digital game to another player in a “family group” for up to 14 days.) Will there be a version of a PS6 with a disc drive? Or will a drive be offered as an add-on? And how will gamers who want to retain access to PS4/PS5 disc-based games react to whichever configurations Sony chooses to offer? What will the final disc-based PlayStation game be?

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Jul 1 • 8:00 AM EDT • Technology • gamefile.news
Azure CLI Password Spray Hits at Least 78 Microsoft Accounts in 81M+ Attempts

Huntress says attackers made 81M Azure CLI password spray attempts from June 12-26, 2026, using ROPC to bypass weak CAPs.

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Jul 1 • 1:46 AM EDT • Technology • thehackernews.com
Yankees ‘Run It Back’ Offseason Plan Receives Interesting Take

Coming into the 2026 MLB season, there was some concern about the New York Yankees, as they decided to "run it back" over the offseason following a disappointing postseason outcome.

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Jun 30 • 10:12 PM EDT • Sports • sports.yahoo.com
Wilmington Small Business Coalition: Building Momentum in 2026 by Heather McWhorter

This article was contributed by Lydia Thomas, UNCW CIE Program Manager. North Carolina continues to be one of the best states to start a business and in 2025, Wilmington, North Carolina earned a spot on the GoDaddy list of the top 10 most entrepreneurial cities in the U.S. While many know Wilmington as small beach town with exceptional food, lots of coffee shops, and fun, vibrant summer activities, a closer look reveals a thriving innovation economy. You’ll find startups emerging across industries including software, healthtech, bluetech, and fintech. At the core of this entrepreneurial ecosystem is the Wilmington Small Business Coalition, with small business advocates and entrepreneur support organizations (ESOs) dedicated to helping founders grow, thrive, and succeed. “No Wrong Door” Established in 2016, the Coalition was designed to make it easier for individuals and small businesses to access resources most suited to their particular needs. The Coalition is designed to have a “no wrong door” entryway into the regional startup ecosystem. Whether you are exploring a new idea sketched on the back of a napkin or leading a more established, growth-stage company, Coalition members can help connect you with the programs, funding opportunities, mentors, and resources best suited to your needs. No matter where you are in your entrepreneurial journey, any Coalition organization can help point you in the right direction. Coalition Members and Leadership Coalition members include the UNCW Center for Innovation and Entrepreneurship (UNCW CIE), AARP, Brunswick Community College Small Business Center, Cape Fear Community College Small Business Center, Cape Fear Region SCORE, Genesis Block Foundation, Network for Entrepreneurs in Wilmington (NEW), Small Business & Technology Development Center (SBTDC), Greater Wilmington Chamber of Commerce, YWCA Living the Dream Center for Entrepreneurship, Carolina Community Impact Fund (CCI Fund), Partner Community Capital, 717mkt Office Collaborative, NC Biotech, and Institute NC. In May 2026, the Coalition held its leadership elections, resulting in the selection of a new executive team. The following officers were elected to serve two-year terms: Chair: Lydia Thomas, UNCW CIE Vice Chair: Diane Lantz, CCI Fund Secretary: Aariene Hansley, Genesis Block Foundation Treasurer: Gloria Monroe, SBTDC Vision for the Wilmington Small Business Coalition In 2026, the Wilmington Small Business Coalition continues its work as a collaborative network of organizations. By connecting programs, expertise, and services across partner organizations, entrepreneurs can more easily find the right support at the right time. Rather than operating in silos, the Coalition aims to function as a unified, cohesive system of support for small businesses and entrepreneurs, ensuring that resources and expertise across partner organizations are visible and accessible. Through stronger collaboration and shared pathways, entrepreneurs can move more seamlessly from idea to startup to growth. Looking to dive into the Wilmington entrepreneurial ecosystem? Connect with any of the Coalition partners to get started! Connect with CIE To learn more about CIE and our services, programs, and events, join the CIE newsletter. You can also follow us on social media: Instagram, Facebook, LinkedIn, TikTok, or YouTube. CIE’s website is uncw.edu/cie. Heather McWhorter is the director of the UNCW Center for Innovation and Entrepreneurship (CIE). CIE supports innovation-forward start-ups and helps to build a vibrant innovation economy for all in southeast NC.

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Jun 30 • 8:00 PM EDT • Business • wilmingtonbiz.com
Generative AI chest X-ray models offer new approach to radiology reporting and quality improvement

While the technology remains investigational in many practices, researchers say it has the potential to improve diagnostic accuracy, streamline AI development and strengthen radiology quality assurance.

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Jun 30 • 5:30 PM EDT • Business • radiologybusiness.com
Anthropic unveils 'Claude Science' AI platform for scientific research

Anthropic on Tuesday launched Claude Science, an AI platform designed to ​help scientists streamline research, analyze ‌data and manage complex computing workflows.

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Jun 30 • 1:02 PM EDT • Science • reuters.com
Opinion: Proposed cuts to federal funding put the stars out of reach for Alaska science students

For students at UAA and across the state, federal research support can be the difference between opportunity here and leaving for good.

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Jun 30 • 11:58 AM EDT • Science • adn.com
Supreme Court upholds principle that almost all born on U.S. soil are American

If the court had struck down birthright citizenship and upheld President Donald Trump’s executive order, the ruling would have had sweeping political, economic and social ramifications.

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Jun 30 • 10:43 AM EDT • Politics • washingtonpost.com
Alan Ritchson's 'Reacher' sets season 4 premiere date a month ahead of 'Neagley' spinoff debut

'Reacher's series is returning for its fourth season this summer, just in time to usher in the premiere of its Maria Sten-led spinoff series.

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Jun 30 • 10:00 AM EDT • Entertainment • ew.com
U.S. Army Contracting Command personnel recognized for streamlining small business procurement

At the FY25 Department of War and Department of the Army Small Business Awards, Army Contracting Command (ACC) was honored for strategic acquisition reforms that diversified and strengthened the defense industrial base.

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Jun 30 • 8:00 AM EDT • Business • dvidshub.net
Plus Therapeutics Provides Mid-Year Business Update Including Corporate Rebranding

Plus Therapeutics to become Cerenome, to trade under new Nasdaq ticker CNSY on August 3, 2026 Affirms 2026 guidance on key milestones Reports positive...

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Jun 30 • 7:30 AM EDT • Business • globenewswire.com
New York Yankees' Potential Catcher Trade Could Get Very Messy

Will the New York Yankees make a trade for a catcher before the MLB trade deadline?

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Jun 30 • 7:00 AM EDT • Sports • sports.yahoo.com
Hormel Foods sells Brazil business

Hormel Foods has signed a definitive agreement to sell its Brazil business to “simplify and streamline its portfolio”.

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Jun 30 • 6:22 AM EDT • Business • just-food.com
Venezuela Health System Strained After Earthquakes, WHO Says

By Emma Farge GENEVA, June ⁠30 (Reuters) - ⁠Venezuela's healthcare system ⁠is under significant strain, the World Health Organization said on Tuesday, with some ‌hospitals damaged and others ‌missing staff after deadly twin ⁠earthquakes ⁠last week. More than 1,700 people have been killed and 5,000 ...

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Jun 30 • 5:47 AM EDT • Health • usnews.com
Ravens’ young core is already showing signs of growth

The Ravens have a new head coach, new coordinators, and a new direction, but much of what has made the franchise successful remains firmly in place.

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Jun 30 • 12:33 AM EDT • Sports • sports.yahoo.com
Stephen Amell is now 'best friends' with soccer star Neymar after replying to years-old DM on live TV

Stephen Amell tells EW about the nail-biting moment James Corden took control of his phone on a live Fox Sports broadcast to respond to a years-old DM from Brazilian soccer star Neymar, with whom he's now 'best friends.'

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Jun 29 • 10:59 PM EDT • Entertainment • ew.com
Oil falls as investors focus on potential Iran-US talks in Doha

Oil prices dropped on Tuesday, with investors eyeing the outcome of potential U.S.-Iran talks in Doha amid weekend missile fire from both sides that tested an interim ceasefire to ​end the four-month-old war.

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Jun 29 • 9:18 PM EDT • Business • reuters.com
New York Yankees’ Jazz Chisholm Jr. Exits Game Against Tigers

The New York Yankees have been struggling in recent games, and their ballclub is continuing to spiral. In the fourth inning, Jazz Chisholm Jr. collided with Jasson Domínguez, ultimately knocking Chisholm to the ground. Status alert: Jazz Chisholm Jr. leaves game Monday.pic.twitter.com/5XyTh98wIX — Underdog MLB (@UnderdogMLB) June 30, 2026 Chisholm exited the game following the […] The post New York Yankees’ Jazz Chisholm Jr. Exits Game Against Tigers appeared first on HEAVY.

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Jun 29 • 8:32 PM EDT • Sports • sports.yahoo.com
Global financial firms pivot to South Korea, cautious on China and India, survey shows

Global financial firms are ​pivoting expansion plans towards South Korea while taking a more measured approach to ‌China and India, according to an industry survey.

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Jun 29 • 8:10 PM EDT • Business • reuters.com
Gaining biological insights through supervised data visualization

Nature Computational Science - This study introduces RF-PHATE, a supervised visualization method that preserves data structure while revealing biological patterns, enabling insights into disease...

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Jun 29 • 8:00 PM EDT • Science • nature.com
Interferometric scattering for optical tomoslicing of transparent solids

Light: Science & Applications - Interferometric scattering for optical tomoslicing of transparent solids

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Jun 29 • 8:00 PM EDT • Science • nature.com
Not many ‘Iron Men’ are left in Major League Baseball

Pete Alonso played his 500th consecutive game this week, although if he wanted that to seem impressive to local fans, he probably picked the wrong city to play in. Alonso, of course, joined the Baltimore Orioles this past offseason. Their franchise record for consecutive games is also the big league record of 2,632 by true […]

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Jun 29 • 8:00 PM EDT • Sports • altoonamirror.com
Henry Winkler says 'there's a string between' him and his 'Happy Days' costar Ron Howard

Winkler and Howard costarred on the '70s sitcom, and they've remained close in the decades since.

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Jun 29 • 6:41 PM EDT • Entertainment • ew.com
Exclusive-NBCUniversal May Enter Video Game Business After Comcast Split, Sources Say

By Echo Wang, Dawn Chmielewski and Milana Vinn June 29 - NBCUniversal is eyeing opportunities in digital gaming and new ⁠entertainment ⁠franchises as the company weighs options for future growth after ⁠its planned spinoff from Comcast, according to three people with direct knowledge of the matter.

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Jun 29 • 4:33 PM EDT • Business • usnews.com
A Defining Moment in Chicago Sports: Chicago Fire FC Acquires Global Football Icon Robert Lewandowski

Poland’s all-time leading goal scorer joins the Fire from FC Barcelona with more than 700 goals for club and country

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Jun 29 • 3:55 PM EDT • Sports • chicagofirefc.com
France Keeps Health Emergency Plan at Highest Level in Case of Another Heatwave

PARIS, June 29 (Reuters) - French Prime ⁠Minister ⁠Sebastien Lecornu said ⁠on Monday he was keeping the country's health emergency response plan, ORSAN, at its ‌highest level for the ‌coming days in view of "a possible ⁠recurrence ⁠of a heatwave episode". Lecornu was speaking at the start of a ...

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Jun 29 • 1:24 PM EDT • Health • usnews.com
Healthcare AI's next big leap: Removing friction from clinical workflows

Rather than just adding more applications, one CMIO says, organizations should focus on using automation and intelligence to eliminate unnecessary steps, reduce clinician burden and streamline care delivery.

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Jun 29 • 10:49 AM EDT • Health • healthcareitnews.com
MLB Power Rankings: Are the Phillies ready to make a declaration on the NL East?

The Phillies have surged into the top five at the same time the Braves are struggling

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Jun 29 • 8:27 AM EDT • Sports • cbssports.com
Ahead of the MLB trade deadline, here’s where the Guardians stand

The Guardians are among the best teams in a weak American League. This is the time for them to capitalize on their situation.

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Jun 29 • 7:00 AM EDT • Sports • nytimes.com
Ahead of the MLB trade deadline, here’s where the Yankees stand

Yankees general manager Brian Cashman is almost always aggressive when he believes in his team.

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Jun 29 • 6:00 AM EDT • Sports • nytimes.com
From invention to impact: Hong Kong Science Fair gives young innovators a wider stage

Organised by the Hong Kong Innovation Foundation, with Sino Group as Principal Patron and the Innovation, Technology and Industry Bureau as Supporting Bureau, the Fifth Hong Kong Science Fair has drawn to a close. Students are already looking beyond their prototypes, with international exchanges and future applications now firmly in sight.

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Jun 29 • 5:27 AM EDT • Science • scmp.com
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Accesa Hosts 5th Edition of Tech in Motion with the Theme Engineering in the Age of Uncertainty

CLUJ-NAPOCA, Romania, June 29, 2026 (GLOBE NEWSWIRE) -- Accesa hosted the 5th edition of Tech in Motion, its annual tech conference, bringing to...

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Jun 29 • 5:00 AM EDT • Business • markets.businessinsider.com
PPDS Brings 'Limitless' TV Entertainment To Historic 5 Star Bellevue Syrene Hotel With Philips MediaSuite

PPDS, the exclusive global provider of Philips Professional Displays, has announced that its Philips MediaSuite TV range has been chosen to deliver seamless access to a virtually limitless world of | Delivering modern luxuries to the 18th century hotel in Sorrento, Philips MediaSuite TVs with cast built in are now bringing seamless access to millions of movies, TV shows, games, and streaming apps to guests at one of Italy's most prestigious and exquisite hospitality destinations.

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Jun 29 • 4:44 AM EDT • Entertainment • livedesignonline.com
Lewandowski close to Chicago Fire switch

Poland's record scorer is set for a big-money move to the MLS after his departure from Barcelona.

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Jun 29 • 4:24 AM EDT • Sports • sports.yahoo.com
ACE WFM Strengthens Workforce System Delivery Approach for Australian Organisations

Melbourne, AUSTRALIA, June 29, 2026 (GLOBE NEWSWIRE) -- ACE WFM, a workforce management consulting provider, has outlined its structured approac...

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Jun 29 • 3:39 AM EDT • Business • markets.businessinsider.com
House committee advances radiology-backed legislation to curb prior authorization

The Improving Seniors’ Timely Access to Care Act seeks to streamline the “often cumbersome and time-consuming” task of approving requests for medical imaging in Medicare Advantage.

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Jun 29 • 2:23 AM EDT • Business • radiologybusiness.com
Detroit Tigers Release 3-Year MLB Player Before Yankees Series

On Monday night, the Detroit Tigers will open up a series with the New York Yankees in the Bronx.They are coming off a 7-5 loss to the Houston Astros on Sunday (at home).Detroit Tigers Release 3-Year MLB PlayerEarlier this week, news came out that the Tigers had released Konnor Pilkington from their organization (h/t MLB […] The post Detroit Tigers Release 3-Year MLB Player Before Yankees Series appeared first on HEAVY.

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Jun 29 • 2:05 AM EDT • Sports • sports.yahoo.com
AB Science reports completion of the step 3 of phase 1, evaluating the combination of AB8939 with venetoclax for the treatment of refractory or relapsed AML

PRESS RELEASE AB SCIENCE REPORTS COMPLETION OF THE STEP 3 OF PHASE 1, EVALUATING THE COMBINATION OF AB8939 WITH VENETOCLAX FOR THE TREATMENT OF REFRACTORY OR RELAPSED ACUTE MYELOID LEUKEMIA THE COMBINATION OF AB8939 WITH VENETOCLAX GENERATED A 67% OVERALL RESPONSE RATE (ORR) AND A 100% DISEASE CONTROL RATE (DCR), WITH NO DOSE-LIMITING TOXICITIES (DLT) OBSERVED, IN A POOR-PROGNOSIS POPULATION WITH ADVERSE GENETICS TREATED IN THE SECOND - TO FOURTH-LINE RELAPSED OR REFRACTORY SETTING Paris, June 2

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Jun 29 • 1:59 AM EDT • Science • finance.yahoo.com
Aligning patient and planetary health: planetary health diet adherence and inflammatory bowel disease prognosis across Western and Eastern cohorts

npj Science of Food - Aligning patient and planetary health: planetary health diet adherence and inflammatory bowel disease prognosis across Western and Eastern cohorts

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Jun 28 • 8:00 PM EDT • Health • nature.com
Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis

Nature Human Behaviour - Mental health concerns among early-career researchers are increasingly gaining attention. This preregistered systematic review and multilevel meta-analysis quantifies...

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Jun 28 • 8:00 PM EDT • Health • nature.com
Patriots Made Wide Receiver Change for Drake Maye

The New England Patriots have made a big change at wide receiver to help franchise quarterback Drake Maye. The post Patriots Made Wide Receiver Change for Drake Maye appeared first on HEAVY.

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Jun 28 • 5:48 PM EDT • Sports • sports.yahoo.com
NBC Announces Plans For Special 'Star-Spangled Sunday'

NBC is having a special "Star-Spangled Sunday" broadcast next weekend. Next Sunday is July 5, 2026. It's a very special Fourth of July weekend this year. It's America's 250th birthday. NBC and Peacock will be airing all 15 MLB games on Sunday, July 5. Two games - Mets-Braves and Padres-Dodgers - ...

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Jun 28 • 4:22 PM EDT • Sports • sports.yahoo.com
Entertainment Firms Face AI Copyright Uncertainty

Editorial analysis: For AI and ML practitioners, unclear copyright rules raise the legal risk and compliance cost of using generative models in production content pipelines. According to The Economic Times, Indian entertainment firms are investing heavily in AI for content creation, but current copyright law, which is tied to human creativity, may not clearly protect AI-assisted or AI-generated works. The Economic Times reports lawyers warn that, without specific legislation or case law, such works face risks of duplication and misuse, complicating licensing, attribution, and monetization for studios and creators. The article highlights that creators and rights holders in India currently have limited legal recourse under existing statutes, per The Economic Times.

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Jun 28 • 2:57 PM EDT • Entertainment • letsdatascience.com
These tiny soil microbes could rescue crops from salty farmland

Researchers have discovered that beneficial soil bacteria give plants an unexpected survival advantage in salty soils. Instead of helping plants keep salt out, the microbes stimulate the production of lignin, a natural compound that strengthens roots and makes plants more resilient. Greenhouse and field tests showed healthier plants and higher yields in salty conditions. The findings could lead to bio-based treatments that help farmers grow crops on land once considered too salty for agriculture.

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Jun 28 • 8:00 AM EDT • Science • sciencedaily.com
Meteor streaks across skies, causes bright flash Sunday morning

Early risers across southeast Louisiana were treated to quite a sight on Sunday morning when a brilliant flash of light streaked across the pre-dawn sky. Around 5:00 a.m., Storm Station viewers reported seeing what looked like a large, vibrant green ball with fire trailing behind it followed by a bright flash. When small space rocks (meteoroids) slam into Earth's atmosphere at high speeds, they create the light streaks we call shooting stars

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Jun 28 • 8:00 AM EDT • Technology • wbrz.com
Pharr grocery store to close after nearly 100 years in business

After nearly 100 years in business, the historic M Rivas Supermarket in Pharr is closing its doors, marking the end of a multi-generational Rio Grande Valley legacy.

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Jun 28 • 8:00 AM EDT • Business • krgv.com
Texas Mental Health Program Reveals 103% Increase in Veteran Enrollment

Emory University treatment is expanding throughout the state at no cost, but many veterans remain unaware of their services.

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Jun 28 • 6:00 AM EDT • Health • military.com
Magnetic sperm and the ugliest shark: science stories of the week

From a lupus breakthrough to why humans drift left when they walk, here are the most interesting scientific developments of the week

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Jun 28 • 2:25 AM EDT • Science • yahoo.com
It's time to wake up America.

It's time to wake up America.

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Jun 28 • 1:36 AM EDT • Sports • foxsports.com
Report: Astros to Call Up RP Miguel Ullola

The Houston Astros are calling up pitching prospect Miguel Ullola, according to a report from Chandler Rome of The Athletic. Ullola, 24, is ranked as the Astros #11 prospect per MLB.com. Ullola was converted to a reliever this season in an effort to help him with his command issues and be someone the team could […]

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Jun 27 • 7:33 PM EDT • Sports • sports.yahoo.com
Gunnar gives back: O's shortstop surprises local kid with specialized cleats

BALTIMORE -- The story of 11-year-old Declan Lefevre’s youth baseball career is inspirational. When Declan was about 4 years old, a doctor noticed his legs were different lengths. And it wasn’t something he would grow out of, either, which is something his parents -- father Jeff Lefevre and mother Nichole

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Jun 27 • 6:57 PM EDT • Technology • mlb.com
Hurricanes Acquire Rights To Top Offensive Blueliner John Carlson

Carolina secures exclusive negotiating rights with the veteran power-play specialist as they look to bolster their defensive core before the free agency market opens.

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Jun 27 • 4:00 PM EDT • Sports • sports.yahoo.com
TherapyGo Announces Milestone as AI-Powered Mental Health Platform Expands Access to Licensed Psychologists

BOCA RATON, Fla., June 27, 2026 (GLOBE NEWSWIRE) -- United Innovation Solutions LLC today announced a major growth milestone for TherapyGo, its ...

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Jun 27 • 3:06 PM EDT • Health • markets.businessinsider.com
GameThread: Detroit Tigers vs. Houston Astros, 6:40 p.m.

Detroit Tigers (35-46) vs. Houston Astros (40-44) Time/Place: 6:40 p.m., Comerica ParkSB Nation Site: The Crawfish BoxesMedia: Detroit SportsNet, MLB.TV, Tigers Radio NetworkPitching Matchup: LHP Framber Valdez (4-5, 3.91 ERA) vs. RHP Kai-Wei Teng (4-6, 4.03 ERA)

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Jun 27 • 1:00 PM EDT • Sports • sports.yahoo.com
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The Weird, Disturbing Origins of the Paleo Diet

Should we all be eating manatees and whales?

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Jun 27 • 12:00 PM EDT • Health • theatlantic.com
Phillies vs Mets Prediction, Picks & Odds for Today's MLB Game

The Phillies have been hot, and our expert MLB predictions expect their winning ways to continue against the lowly Mets.

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Jun 27 • 11:35 AM EDT • Sports • sports.yahoo.com
CARE AT HOME GUARANTEE CORPORATION FILES PATENT APPLICATION FOR PROPRIETARY BUSINESS MANAGEMENT SYSTEM

Miami, FL, June 27, 2026 (GLOBE NEWSWIRE) -- CARE AT HOME GUARANTEE CORPORATION ('the Company'), a Florida-based Senior Care Solutions company, ...

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Jun 27 • 3:38 AM EDT • Business • markets.businessinsider.com
National Science Foundation finds no violations in Texas A&M research security contract

U.S. Rep. John Moolenaar, a Michigan Republican who chairs the House of Representatives' select committee on China, had urged the NSF to pause funding for a project known as SECURE.

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Jun 26 • 9:01 PM EDT • Science • yahoo.com
With first sweep since May, Padres turn to division rivals

FriarWatch: June 26 Edition

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Jun 26 • 5:45 PM EDT • Sports • sports.yahoo.com
The mediocre American League will define this year's MLB trade deadline
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Jun 26 • 4:12 PM EDT • Sports • sports.yahoo.com
Netflix wants everyone in your house to have their own email login now

Netflix is quietly changing how shared accounts work, one profile at a time.

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Jun 26 • 3:21 PM EDT • Technology • androidcentral.com
Art Garfunkel shares secret to lasting 38-year marriage: 'I can't live without my wife being in accord'

'Bridge Over Troubled Water' singer Art Garfunkel shares secret to his lasting 38-year marriage with wife Kathryn 'Kim' Luce: 'I can't live without my wife being in accord.'

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Jun 26 • 3:00 PM EDT • Entertainment • ew.com
Minuteman Press Franchise Owner Dave Forster Reflects on 40 Years in Minneapolis

MINNEAPOLIS, June 26, 2026 (GLOBE NEWSWIRE) -- Dave and Sandy Forster are the owners of Minuteman Press in Minneapolis, MN since February of 198...

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Jun 26 • 11:35 AM EDT • Business • markets.businessinsider.com
Music Legend Axes Shows After Onstage Health Scare

Lionel Richie was hospitalized on the opening night of his tour with Earth, Wind & Fire after feeling dizzy on-stage.

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Jun 26 • 9:36 AM EDT • Health • thedailybeast.com
Chaotic Push to Train Staff for US Ebola Outbreak Facility Alarms Health Workers

The three-day session focused more on administrative tasks than spread prevention.

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Jun 26 • 9:15 AM EDT • Health • bloomberg.com
New Linux pedit COW Exploit Enables Root Access by Poisoning Cached Binaries

CVE-2026-46331 lets local users gain root on affected Linux systems by corrupting page-cache memory through act_pedit.

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Jun 26 • 9:00 AM EDT • Technology • thehackernews.com
St. Norbert, FVTC partner to make business degree transfer 'seamless'

St. Norbert and Fox Valley Technical College are joining forces to make getting a bachelor's in business at SNC easier.

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Jun 26 • 6:04 AM EDT • Business • greenbaypressgazette.com
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Meeting the dozen new inductees in the 2026 Louisiana Sports Hall of Fame class

New inductees for Louisiana Sports Hall of Fame honored at press conference

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Jun 26 • 12:05 AM EDT • Sports • ksla.com
Vance dismisses Watergate scandal, says ‘deep state’ went after Nixon

The vice president said he admired Nixon and drew parallels between the past president, who resigned amid pressure in 1974, and Trump today.

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Jun 25 • 9:06 PM EDT • Politics • washingtonpost.com
It's Xbox's turn (again), as console prices keep going up

Microsoft announced a price hike for the Xbox Series consoles today, the third in little over a year. Effective August 1, the Xbox Series S, which launched in 2020 for $300, will cost $500 in the U.S. The Xbox Series X, which launched in 2020 at $500, will go for $800. This follows a round of PlayStation 5 price increases from Sony this spring, and a slow-motion increase for Nintendo’s Switch 2, which will kick in in the U.S. in September. (Mind you, there were also eight video game industry price hikes in six months of 2025). The chart up top shows the sudden ascent of console prices over the past year, a sudden surge in an already unusual hardware generation. Prices had been flat for years, now “up” is the new “flat.” Game console prices used to go down across the length of a console generation, but not this time around. Microsoft’s explanation for the new price hike today: We hoped another price increase would not be necessary, and we have spent the last several months working with suppliers on options. Unfortunately, console storage and memory prices have increased by more than 2.5x and we expect another doubling by the fall of 2027. The entire consumer electronics industry is struggling with the current components crisis, but the effects are particularly hard on consoles. Unlike phones, computers, speakers, and other consumer devices, consoles are typically not sold at a profit, but instead for less than they cost to make. This is an issue well beyond game consoles. Apple announced price hikes on its computers and tablets today as well. Game File is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Item 2: Brutal Bungie cuts Bungie laid off “most” of its Destiny development team and some developers who worked on Marathon, the newest game from the struggling Sony-owned studio. A WARN notice issued by Sony to Washington State, where Bungie is based, tallied cuts impacting 292 workers, effective next month. That’s strictly for Bungie/Sony jobs in Washington and wouldn’t account for any elsewhere. The video I clipped below shows the redacted list of Bungie cuts filed to Washington State officials. As you’ll see, I had to scroll for a while… In a note emailed to PlayStation workers and published online, PlayStation game studios chief Hermen Hulst offered the following explanation for these latest cuts at Bungie: This is painful news, especially for talented colleagues whose roles have been eliminated. This decision was made only after extensive discussion and careful consideration, and I want to provide some context on how we arrived here. Over the past several months, together with Bungie leadership, we reviewed the studio’s long-term direction, development priorities, resource needs, and role within our broader portfolio strategy. We explored multiple alternatives before concluding that a reduction was necessary to align the studio’s resources with its current priorities and long-term goals. In 2022, Sony bought Bungie for $3.7 billion. The studio’s marquee game, the multiplayer live service shooter Destiny 2 was losing popularity at the time. Its next game Marathon, released earlier this year, has been well-reviewed but had a slow start. Bungie is renowned for making great shooter games, and Destiny fans have mourned the wind-down of Destiny 2. They’ve also expressed bewilderment over reports that Destiny 3 is not, per Bloomberg, immediately in the cards.

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Jun 25 • 8:21 PM EDT • Technology • gamefile.news
Heastie brushes off growing DSA influence, defeat of incumbents in Albany

Heastie sought to put the results into context while speaking with reporters at an unrelated event in Schenectady on Thursday.

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Jun 25 • 8:11 PM EDT • Politics • spectrumlocalnews.com
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Generative artificial intelligence creates delicious, sustainable, and nutritious burgers

npj Science of Food - Generative artificial intelligence creates delicious, sustainable, and nutritious burgers

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Jun 25 • 8:00 PM EDT • Science • nature.com
Dopant-localized mechanoluminescence in simple oxides

Light: Science & Applications - Dopant-localized mechanoluminescence in simple oxides

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Jun 25 • 8:00 PM EDT • Science • nature.com
Mental health as both outcome and determinant in climate adaptation

Nature Climate Change - Mental health should not be viewed solely as a passive outcome of climate adaptation. Rather, it serves as a key determinant of cognitive capacity and shapes the...

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Jun 25 • 8:00 PM EDT • Health • nature.com
Evaluating the robustness and readiness of large frontier models in health AI applications

Nature Medicine - Adversarial evaluation of leading AI models uncovers gaps between benchmark success and robustness, highlighting limitations in current health AI benchmarks and their ability to...

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Jun 25 • 8:00 PM EDT • Health • nature.com
MLB All-Star 2026: Shohei Ohtani and Ernie Clement receive automatic spots after winning Phase 1 of fan vote
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Jun 25 • 6:14 PM EDT • Sports • sports.yahoo.com
M5 Ultra Mac Studio Could Launch in 2026 With Up to 768GB of RAM

Despite price increases across the Mac line, Apple is still planning to release a new Mac Studio as soon as this year, reports Bloomberg. Apple plans to introduce a new M5 Ultra chip as the final option in the M5 family before it transitions to the M6, M7, M7 Pro, and M7 Max. The M5 Ultra will come in a new version of the Mac Studio, which hasn't been updated since March 2025.

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Jun 25 • 5:30 PM EDT • Technology • macrumors.com
Making Our Own Luck

We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.

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Jun 25 • 4:48 PM EDT • Science • goodscience.substack.com
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Senate Democrats announce election observer program

The program will put trained, official observers on the ground to observe activities around polling places

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Jun 25 • 2:22 PM EDT • Politics • spectrumlocalnews.com
Platner, Collins’ campaign spar over federal contracts

Platner released a multi-point plan he calls “a corruption crackdown,” which covers issues such as big money in politics, lobbying activities by former members of Congress, and making it more difficult for presidents to cash in on their position while in office.

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Jun 25 • 2:04 PM EDT • Politics • spectrumlocalnews.com
Reflecting Pool liner was cut with knife or razor, National Park Service says

A parks official made the statement in a court document filed late Wednesday

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Jun 25 • 12:45 PM EDT • Politics • spectrumlocalnews.com
Reflecting Pool liner was cut with knife or razor, National Park Service says

A parks official made the statement in a court document filed late Wednesday

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Jun 25 • 12:45 PM EDT • Politics • spectrumlocalnews.com