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Here's how iPhone Duo treats apps not optimized for the foldable display
Apple has officially announced the iPhone Duo, its first foldable display device. Additionally, the company has detailed how third-party apps...
Sacramento drive-in hosts free movie night with kid-friendly options. What to know
Discounts on nachos, bounce houses and other activities will accompany six free movies at the West Wind theater’s movie night.
Georgia Fans Are Absolutely Furious About This
Georgia football fans will pay for a lot of things. Tickets. Parking. Donations. Merchandise. Streaming subscriptions. Apparently, game highlights are next. Georgia promoted its traditional “Victory Highlights” video following its 63-3 destruction of Tennessee State , except there was one massive catch. The full video was placed behind the Glory Glory subscription service, which starts…
AirPods 5 Announced With Improved Noise Cancellation, Audio Quality, and More
Apple today introduced AirPods 5, bringing Active Noise Cancellation to its entry-level wireless earbuds at a starting price of $129. Apple says AirPods 5 remove up to 50% more external noise than AirPods 4 with Active Noise Cancellation. A redesigned acoustic architecture and updated Adaptive EQ also promise richer, more detailed sound, while an improved Transparency mode makes nearby voices and sounds more natural.
Electrical Trade Attracts New Workers; Small Business Optimism Dips in August
WARREN, Ohio – Women are finding a growing place in the electrical trades, with apprenticeship programs in the Mahoning Valley reporting increased interest and enrollment. Young apprentices are gaining experience across residential, commercial and industrial work while preparing for careers in the field.
Healthy Living with USA Health: Enlarged Prostate Treatment Options
In this Healthy Living, we talk with Troy M. Sofinowski, M.D., an Endourologist at USA Health.
Apple Unveils A20 Pro as First 2nm Smartphone Chip
Apple today revealed the A20 Pro chip in the iPhone 18 Pro and iPhone 18 Pro Max, built on a brand new architecture using 2nm process technology. Apple described the A20 Pro as "an exceptional chip that sets a new bar for mobile computing". The chip has a 6-core CPU design with two new super cores that Apple says are up to 20% faster, calling them "desktop class" and "the fastest in any smartphone," alongside four new efficiency cores.
How to watch the US Open without cable today
Here's how to watch the US Open today, including TV channels and live streaming options.
Policy vs. Practice: Digitizing Mexico's Healthcare Ecosystem
Mexico's new digital health law mandates EHRs and telemedicine, but market and infrastructure gaps could slow real-world adoption.
Martin Herlihy departs 'Saturday Night Live'
Martin Herlihy attends the premiere of 'Roommates' at The Egyptian Theatre Hollywood on April 13, 2026, in Los Angeles, California. (Kevin Winter/Getty Images)
Prisma Health to host free webinar on menopause
Prisma Health is offering a free webinar on Sept. 23 to help women better understand menopause, recognize common symptoms, and explore treatment options that can improve their quality of life.
New Business: Paradise Coffee owners bring grab-and-go options to Point Tiburon Plaza
Paradise Coffee at Point Tiburon Plaza in Tiburon sells Cubano sandwiches, breakfast burritos and bonbons from a Tiburon chocolatier.
Entertainment Listing: Sept. 9
Wednesday Sept. 9 Little Nashville • Marion Writers Rounds, 6 p.m. PK’s • Carbondale Trivia, 8 p.m. Advertisement Booby’s • Carbondale Gritty Biscuit & Guitar Rabbit, 8 p.m. Hangar 9 • Carbondale Karaoke Night, 8 p.m. Thursday Sept. 10 Booby’s • Carbondale Open Mic Karaoke Night, 8:30 p.m. Hangar 9 • Carbondale ...
Drew Anderson just gave Tigers a $10 million decision
Drew Anderson has gone from a flexible bullpen arm to a legitimate piece of Detroit’s rotation. Now the Tigers must determine whether that transformation is worth exercising his $10 million club option for 2027.
IMG_6723.jpeg
Good Day Cafe's burger and fish sandwich (pictured here) are great options in Oxford, Mississippi.
All New iPhone 18 Pro and 'iPhone Duo' Colors Leaked
Ahead of Apple's annual iPhone event at 10 a.m. Pacific Time today, Bloomberg's Mark Gurman has leaked all of the color options for the iPhone 18 Pro, iPhone 18 Pro Max, and the first-ever foldable iPhone named the iPhone Duo. iPhone 18 Pro and iPhone 18 Pro Max color options:Black Light Blue Burgundy Silver Burgundy has also been described as Dark Red or Dark Cherry.
Steelers holding leverage in Joey Porter Jr. contract talks
The Pittsburgh Steelers maintain crucial franchise tag options as negotiations with cornerback Joey Porter Jr. enter a critical pre-season stretch.
Influencer marketing can bring a boom, but will it last?
Influencer marketing has become a polarizing issue, with some businesses and venues pushing back against creators while others see significant value in the exposure they can generate, Inc. reports. For small and midsize businesses, influencer attention can deliver dramatic increases in traffic and sales, but it also comes with risks and operational challenges. In Michigan, […]
Norman Sports Hall of Fame accepting nominations for inaugural induction class
The Norman Sports Hall of Fame is accepting nominations for its inaugural induction class, recognizing accomplishments across youth, amateur, high school, collegiate and professional athletics.
Ascension economic development pipeline holds $22B in potential investment
The Ascension Parish Economic Development Corporation has recorded $347 million in announced capital investment and 46 new jobs so far this year, according to its president and CEO, Kate MacArthur. … Already an INSIDER? Sign in. Already an INSIDER? Sign in
The ‘amnesia tax’: How frictionless payments fuel mindless spending
The rise of frictionless payment technology may be making it easier for consumers to lose track of their spending, contributing to what the author calls “budget amnesia,” The Washington Post reports. One single mother with $80,000 in student debt reviewed a year of bank statements and discovered that her finances weren’t being undermined by major […]
OneSkies Makes Business Class More Accessible
TAMPA, Fla., Sept. 09, 2026 (GLOBE NEWSWIRE) -- OneSkies, a travel service focused on premium international airfare, is helping U.S. travelers explore competitive business class flight options for long-haul trips to destinations across Europe, Asia, the Middle East and beyond. As travelers increasingly prioritize comfort on international journeys, business class is attracting interest beyond traditional corporate travel. Vacationers, entrepreneurs, couples, families and experienced travelers are
Can Your Business Afford a Cyberattack? - Small Business & Entrepreneurship Council
By Rieva Lesonsky – Most small business owners know a cyberattack could disrupt their operations. But they may not realize just how expensive that disruption could be. Verizon Business’s 2026 Breach Impact Study (BIS) looked at about 70,000 cyber insurance claims, of which more than half (38,000) were paid to policyholders to cover insurable cyber incidents from January […]
Bucs $14M Addition Expected to Have ‘Prominent’ Role
One of the tougher fantasy football backfields to decide is the Tampa Bay Buccaneers. While many will be debating between Bucky Irving and Kenneth Gainwell as the top option in fantasy, Greg Auman of Fox Sports weighed in with a strong case for Gainwell. Auman noted that Zac Robinson has a chance to significantly improve […] The post Bucs $14M Addition Expected to Have ‘Prominent’ Role appeared first on HEAVY.
Baptist Health Corbin encourages community to get flu shots, offers appointment-free vaccinations
Baptist Health is reminding people of the importance of an annual flu shot and of opportunities to get vaccinated.
The 20 colleges with the best food, campus dining
Niche identified the top US colleges for campus food options, based on student reviews and meal plan costs.
Optimal Blue announces initial speaker lineup for 2027 Summit
IMAGE CAPTION: Optimal Blue announces initial speaker lineup for 2027 Summit | Optimal Blue today announced its initial speaker lineup for its 2027 Optimal Blue Summit, including Analyst, ESPN Monday
Optimism index: Small business owners feel good now, are wary about future
The National Federation of Independent Business released its August small business optimism index on Tuesday and it showed a small dip to a reading of 98.7 from 99.8 in July. But the optimism index remained just above its long-term average …
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
The Cost of Cutting American Science: How Federal Cuts Diminish Public Health Capacity
Among the federal government’s many responsibilities is the work it does to protect public health. Federal agencies monitor our food supply to ensure safety, conduct research to better understand emerging health threats, provide funding for public health programs in communities and work to detect and respond to disease outbreaks. Americans rely on these efforts every day—in a 2024 online survey, 74% of respondents said that “if the federal government issued safety guidance about food you eat regularly,” they would follow it. Changes to Federal Public Health Capacity The Trump administration’s efforts to reshape the federal government have resulted in significant impacts on our nation’s public health capacity over the past 20 months, affecting the response to health concerns such as measles, Ebola and cyclosporiasis. Agencies with core public health, food safety and disease prevention responsibilities experienced large workforce decreases during the first year of the administration. At the Centers for Disease Control and Prevention, for instance, the workforce in February 2026 was 26.7% smaller than in September 2024 before the start of the Trump administration. The Food and Drug Administration saw a similarly steep decline of 21.6%. Agencies such as the National Institutes of Health, Substance Abuse and Mental Health Services Administration and Food Safety and Inspection Service also experienced large workforce decreases. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); Changes can also be seen in crucial public health occupations. The number of federal food inspectors, for example, decreased by more than half between September 2024 and February 2026, going from 1,035 to 473. This is the lowest number of food inspectors employed by the federal government since at least 2005. By February 2026, there were also 33.3% fewer federal public health program specialists, whose work includes advising federal funding recipients on public health activities and analyzing the effectiveness of public health programs. Government’s capacity is diminished as employees with specialized knowledge and experience in protecting the public and responding to health risks depart, leaving agencies less prepared to carry out their public health missions. There also have been vacancies in critical high-level leadership positions at public health agencies, most notably at the CDC, which had a permanent Senate-confirmed director for less than a month between January 2025 and early August 2026. Although the CDC has previously been led by acting directors at the start of an administration, the nearly yearlong gap since the departure of the administration’s first permanent director in August 2025 is without precedent. As of August 2026, the FDA is also currently without a Senate-confirmed commissioner following the previous commissioner’s resignation in May 2026. Additionally, public health agencies are experiencing increased politicization of their leadership ranks. In agencies such as the CDC and Food Safety and Inspection Service, the number of individuals in the Senior Executive Service—the most senior career leaders in government—has declined significantly, while at the same time the number of political appointees has reached record levels. (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); (function(){function e(){window.addEventListener(`message`,function(e){if(e.data[`datawrapper-height`]!==void 0){var t=document.querySelectorAll(`iframe`);for(var n in e.data[`datawrapper-height`])for(var r=0,i;i=t[r];r++)if(i.contentWindow===e.source){var a=e.data[`datawrapper-height`][n]+`px`;i.style.height=a}}})}e()})(); At the CDC, for example, the number of career SES decreased 42.9% between December 2024 and February 2026, while the number of non-Senate confirmed political appointees at the agency was six times larger than the agency’s historical average from 2009 and 2024. Knowledgeable career leaders are integral to the ability of public health agencies to carry out their work with scientific integrity and professional judgment, and rapid leadership turnover and increased politicization threaten agencies’ ability to make evidence-based decisions to protect our health. The upheaval and politicization in public health agencies have also negatively affected employee engagement. Strong employee engagement is crucial to the ability of agencies to carry out their mission and successfully provide essential services to the public. In the 2025 Public Service Viewpoint Survey conducted by the Partnership for Public Service, the Department of Health and Human Services—which encompasses major public health agencies such as the CDC and FDA—had an employee engagement and satisfaction score of 20.4 out of 100, one of the lowest among large agencies. Only 2.8% of HHS employees indicated trust in their political leaders and only 8.7% reported confidence that they could report a suspected violation of law or regulation without retaliation. Employees at HHS also reported that the agency’s ability to provide services to the public had suffered. Nearly half of employees at HHS, 47.5%, said their work unit was worse at delivering quality services compared to its performance in 2024. In addition, 57.8% said their work unit was performing worse at fulfilling stakeholder needs. In addition to the work done within federal agencies, the federal government also distributes significant funding for public health and disease prevention work to state and local governments, nonprofits and small businesses—funding which has been significantly disrupted. At the CDC, for example, there was a 71.9% decrease in the amount of project grant funding issued in fiscal year 2025 compared to fiscal year 2024. The FDA also issued far less funding in fiscal year 2025—a 21.3% decrease from its fiscal year 2024 funding. Changes in federal funding include the ending of grants to community organizations that worked on HIV prevention and the cancellation of funding for research into improvements to patient safety and healthcare quality. These changes go beyond federal agencies to impact the broader public health ecosystem, including the state and local health departments responsible for much of the on-the-ground public health work in their communities. About 80% of the CDC’s domestic funding is directed towards state and local partners—meaning that cuts to CDC funding can ultimately result in cuts to state and local public health capacity. Federal agencies also provide expertise and assistance to state and local health agencies as they deal with particular health challenges, but workforce cuts have resulted in fewer federal employees available to help. The Impact of Changes to Public Health Capacity These changes to federal public health capacity are not abstract concerns. Disrupted programs, reduced funding and lost expertise at public health agencies across all levels of government threaten the public’s physical well-being and safety. In some cases, this has already led to harm. The most immediate impacts of federal cuts were seen in interruptions to ongoing public health programs and crisis responses. In one instance, when CDC grants were canceled during the 2025 Texas measles outbreak—the most severe measles outbreak in 25 years—public health officials in Lubbock, Texas were forced to pause parts of their measles response work supported by the frozen funding. Lubbock’s director of public health further said that a lack of available CDC experts to reach out to for advice “definitely” impacted the department’s response to the measles crisis. Cuts to federal funding also forced Dallas County Health and Human Services to cut staff and cancel 50 community vaccination clinics during the outbreak. Public health work outside of major outbreak responses was also disrupted. For example, in April 2025, the Milwaukee Public Health Department was unexpectedly unable to reach experts on lead poisoning due to firings at the CDC when responding to concerns about lead contamination in Milwaukee public schools. Due to federal workforce cuts, several programs at the CDC, including Alzheimer’s and epilepsy programs, have also become trapped in limbo—existing on paper, but without the staff necessary to operate. More recent crises reveal how federal cuts have weakened the public health infrastructure needed to prevent and respond to dangerous new outbreaks. Internationally, cuts at the U.S. Agency for International Development eliminated funding for disease testing and contact tracing abroad, which delayed detection of and responses to the 2026 Ebola outbreak in the Democratic Republic of Congo. While international outbreaks may seem far removed, the unchecked spread of disease in any country can quickly pose a danger to economic well-being, security and health around the world. Within the United States, public health cuts inhibited responses to the summer 2026 outbreak of the food-borne parasite cyclospora. At the federal level, cuts to funding for lab equipment and for CDC staff with expertise in parasitic infections—including 9 out of 11 staff members at the lab responsible for identifying parasitic outbreaks in 2025— contributed to the largest reporting delay in outbreak cases at the CDC in 15 years. Conflicting communications from the FDA about the source of the outbreak, which followed cuts to the agency’s communications department, additionally led to confusion among the public about how to best avoid infection. At the same time, cuts to HHS funding and support for local and state public health slowed some health departments’ responses to the crisis. The exact costs of these delays, constraints and confusion in public health responses are difficult to estimate. However, their message is clear: federal cuts have already made containing threats to public health even more of a challenge. Conclusion Protecting public health—from food safety to disease prevention—is one of the federal government’s most important missions. Dramatic and haphazard cuts to federal agencies and funding have already disrupted the public health system, impacting the response to challenges such as measles, lead poisoning and cyclosporiasis. The U.S. public health system needed improvement before these disruptions. Since 2022, federal leadership and coordination in response to public health outbreaks has been on the Government Accountability Office’s High-Risk List of areas in need of attention to improve government effectiveness and efficiency. Recent cuts only compound these concerns. The chaotic dismantling of government and resulting disruptions to crucial functions like public health and disease prevention highlight the need for meaningful reform and concrete policy proposals to reimagine how government can better serve the public and be more effective, responsive and accountable. To learn more about the impact of federal cuts to public health and science more broadly, visit The Cost of Cutting American Science. Learn more For more information on the Partnership for Public Service’s government reform initiative, visit Government for a New Era. View here In line with The Cost of Cutting American Science, federal workforce data in this brief is as of February 2026
Cleveland Clinic Partners with Luminai to Transform Health System Operations
Collaboration applies AI automation to complex administrative processes at enterprise scale – with fax referral transcription as the first use case
NFIB reports slight dip in small business optimism
Owners cite weaker sales, inflation and supply chain strains, while many still struggle to find qualified workers.
Besxar is building an orbital semiconductor factory, one SpaceX rocket at a time
If you want to manufacture in space—and bring the products back again—there's a limited set of options: Wait to go to the International Space Station, or
Accenture and Google Cloud establish Gemini Enterprise Business Group
The partnership aims to accelerate enterprise adoption of agentic AI, offering expanded industry expertise and technical resources.
Science researchers honoured by RSC
New fellows are leading experts on sustainable agriculture, fish adaption and plant immune response.
AT&T Business and Amazon Leo form strategic partnership
AT&T Business and Amazon Leo have agreed to bring broadband services to AT&T Business customers nationwide, making AT&T is the first major U.S. telecom provider to offer converged connectivity solutions that include Amazon Leo’s low Earth orbit (LEO) satellite services. With the agreement, AT&T Business customers have multiple access connectivity options, which the company said […]
France to reduce corporate tax surcharge and ease employee buyouts in 2027 budget, PM says
France plans to reduce, but not abolish, the exceptional corporate tax surcharge imposed on very large companies in its 2027 budget, Prime Minister Sebastien Lecornu said in a letter to executives on Wednesday, pledging tax stability to support growth.
Overmars resigns as Royal Antwerp sports director due to health issues
Soccer great Marc Overmars is stepping down as Royal Antwerp's sports director due to health issues. Overmars, who joined the Belgian club in 2022, explained his decision in a letter to supporters published on Wednesday as he mentioned “all the fatigue that has built up over the years and the enormous amount of stress.” “You all know that my health has not been optimal,” he wrote.
Overmars resigns as Royal Antwerp sports director due to health issues
Soccer great Marc Overmars is stepping down as Royal Antwerp's sports director due to health issues. Overmars, who joined the Belgian club in 2022, explained his decision in a letter to supporters published on Wednesday as he mentioned “all the fatigue that has built up over the years and the enormous amount of stress.” “You all know that my health has not been optimal,” he wrote.
Military Toxic Exposures Appear to Affect Both Mental and Physical Health in Veterans
Environmental hazards encountered during military service, such as Agent Orange and toxins from open-air burn pits, are known to be linked to adverse physical health outcomes. The VA recognizes them as presumptively service related under the Agent Orange Act of 1991 and the Promise to Address Comprehensive Toxics Act of 2022.
Singapore’s Prime Minister Gets a Big Raise
Singapore’s prime minister, Lawrence Wong, got the bump as part of a longstanding policy to pay high salaries to public servants in order to attract top talent and prevent corruption.
5 fun events happening in Madison this week, Sept. 10-16 🎤🧶🍺
This week around Madison, see SNL's Kam Patterson, check out the Great Wisconsin Quilt Show, celebrate Oktoberfest at Working Draft and more.
Can Ohio business leaders shift data center opinions? Business leaders hope so
Ohio business leaders are launching a campaign to counter what they see as data center misinformation and convince skeptical communities that the facilities can be good neighbors.
The science of friendship and loneliness
Assistant professor of psychology Jessica Ayers’s new research challenges assumptions about the kind of friendships we need
How a fight to save Wisconsin's Black babies keeps hitting a dead end
Black Caucus members Shelia Stubbs, LaTonya Johnson, Margaret Arney, Sequanna Taylor and Dora Drake are on a mission to end the infant mortality crisis.
Editorial | Black infant mortality rate is a public health crisis
Editorial: Despite a mortality rate three times higher than white infants, Republicans like Tom Tiffany have opposed efforts to address race-based inequities in healthcare.
Wisconsin volleyball doesn't panic after tough start to season
Coach Kelly Sheffield contrasts his Badgers' response to adversity with a scene from "Animal House."
NEA partner Aaron Jacobson weighs in on open versus closed
Big Tech may be grabbing attention for its powerful new models, but investors like NEA's Aaron Jacobson want companies to explore their options.
Mistrust of US government information is rising across major issues, new poll shows
A new AP-NORC/USA Facts poll finds that Americans are more skeptical of government information than they were a few years ago, with majorities now saying they have little or no trust in federal government information about elections, foreign affairs or the environment.
Here is what to do if healthcare costs are eating into your raises
An insurance executive explains how soaring healthcare costs eat into raises, and how workers should discuss alternative options with their company.
Google finally brings Gemini Daily Brief to free users
Google is expanding Gemini Daily Brief to even more users in the US, including those without a Google AI Plus, Pro, or Ultra subscription.
Anak Krakatau Rumbles Again
A powerful eruption from the Indonesian volcano lofted ash into the atmosphere, disrupting thousands of flights and degrading air quality.
Hawaiian Telcom Unveils Future-Ready Business Fiber Platform Engineered for 10 Gig Connectivity
Hawaiian Telcom announced enhancements to its business fiber internet portfolio, including expanded symmetrical upload and download speeds across Fioptics Business Internet plans and the introduction of Fioptics Advanced WiFi for business customers. Together, these enhancements provide Hawaiʻi businesses with faster, more scalable connectivity backed by a fiber network engineered to support connectivity solutions up to 10 Gig.
NASA X-59 explainer: Science of sonic booms
The most common misconception about sonic booms is that they’re just the sound created at the moment when an aircraft “breaks the sound barrier.”
UTA health center to hold kickoff for free flu shots Wednesday
The clinic is next to Brazos Park, and appointments are optional but encouraged.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Small business owners feel good now, wary about what's ahead: NFIB optimism index
Small business optimism dipped in August but stayed above its long-term average as uncertainty remained elevated, prompting some owners to delay bigger investments.
Red Dead Redemption 2 free expansion is a new story set within an alternate timeline
If you need more post-game content, you've found it.
Louisville opens first mental health crisis center
Louisville’s first mental health crisis center is now open, offering walk-in help and a new option beyond jail or the emergency room.
Arsenal youngster in international tug-of-war
Ceadach O’Neill’s international future remains unresolved, with Northern Ireland and the Republic of Ireland both still possible options for the Arsenal youngster.Photo by Cameron Smith/Getty Imag...
Mapping the Global Health Landscape: Analysis of Fourteen International Organizations
The global health architecture includes a number of diverse international organizations with different mandates, governance models, financing structures, and operational approaches. This KFF resource looks across a range of variables to provide a descriptive mapping of 14 key global health and related international institutions. It is intended to inform discussions about synergies and coordination, duplication, comparative advantage, shared challenges, and architectural reform.
At rally to save Academy of Natural Sciences museum, protesters urge Drexel to 'act like it's an emergency'
Local lawmakers and scientists outlined several options to preserve the museum, which is due to close Sept. 30.
Exclusive: Two of gaming’s biggest names are making a big investment in gaming’s future
The first thing to know about the Nova Games Foundation is that it isn’t about The Game Awards. And it’s not about PlayStation. The ambitious new grant program is the brainchild of Geoff Keighley and Mark Cerny. Keighley is the host of The Game Awards, Summer Game Fest and Opening Night Live. Cerny is a game designer of some 45 years and the lead architect for the PlayStation 4 and 5. But this new thing, which they’re revealing through Game File, isn’t about their day jobs. It’s an unaffiliated, standalone philanthropic project. It’s a bet on the artistic future of video games and a way, they tell me, to give back. “I’m nearing the end of my career,” Cerny recently told me over email. “I’m not done yet, but paying it forward—in the best way possible—is very much on my mind these days,” The Nova Games Foundation is a university-affiliated fellowship program, intended to offer six-figure grants to 20 young game designers each year, potentially for decades to come. It will offer no-strings-attached funding along with mentorship from games industry leaders, a combination intended to aid the development of groundbreaking new games, Cerny and Keighley told me. Nova will begin accepting applications in December, from class of 2026 and 2027 students from 13 affiliated gaming programs at universities in eight countries. The schools working with Nova include the New York University and the University of Southern California in the U.S., along with Abertay University in Scotland, Cnam-Enjmin in France, TH Köln in Germany, and the Royal Melbourne Institute of Technology in Australia, Cerny and Keighley said. The plan: $100,000 per recipient, with about a quarter of Nova fellows eligible for up to $500,000 more for projects that are shaping up particularly well. Payments will be delivered based on development milestones, and recipients will own their games. Nova will help promote the work, and developers will be free to pursue the publishers and platforms of their choice. Nova can help introduce fellows to publishers, but won’t take a cut. “I’ve always wanted to give back, but given my role in the industry, I’ve never felt it appropriate to commercially invest in games,” Keighley told Game File. “I’ve never owned stock in a game company or taken a financial stake in a game. Nova is philanthropy: we aren’t taking equity or looking to recoup the grants. The return we’re hoping for is creative—helping new voices make games and find their footing. “Mark and I have each made multi-million-dollar donations to establish the foundation, and we intend to keep contributing. We hope others will join us.” Cerny and Keighley have already hired an executive director, John Maconga, and a head of grants, recent Game Developers Conference director Ashley Corrigan, to help launch the effort. They’re working to recruit game industry leaders to join the effort. Keighley says “dozens of leading game directors have already expressed interest in contributing their time.” To name one, they’ve already gotten Josef Fares, lead designer from It Takes Two and Spit Fiction studio Hazelight on board with a donation and pledge to help out. “I’m proud to support Nova because it gives the next generation of creators the freedom to explore their creativity and hopefully bring their unique visions to life,” Fares told Game File. A plan forged from a friendship Keighley and Cerny have known each other a long time. It’s been so long, Cerny isn’t even sure exactly when they met. “We travel in much the same circles and I’m sure first intersected in the 90s or early 2000s,“ Cerny said. Keighley thinks it might have been during his stint writing a column about the mid-’90s console 3DO for a gaming magazine while Cerny was working on games with Crystal Dynamics or on Way of the Warrior with Naughty Dog. They became genuine friends about a 10 years ago, Keighley said, as they bonded over a shared love of games and a hope to improve the industry. “About a decade ago, we started having dinner a few times a year in LA,” Keighley said. “Just to catch up on life and the industry. Those conversations continued over Zoom during COVID. Nova grew out of that friendship and a question we kept coming back to: ‘What could we do to help the next generation of game directors get started?’” Keighley credits Cerny with the idea to figure out a way to put their money and time back into the industry. At one of those dinners, Keighley proposed the idea of a fellowship program. He’d recalled applying for a Rhodes Scholarship when he was younger. “Spoiler: I didn’t get it,” he said. He’d admired the MacArthur Foundation’s so-called “genius grants.” He liked these kinds of programs that recognized people’s talents and gave them the financial boost and the freedom to realize their potential. With Cerny, he had pondered what a game industry version of that could be. Keighley liked the idea of centering the fellowship on students, drawing inspiration from the accomplishments of Jenova Chen, the USC game design graduate who went on to lead the creation of gently moving, ambitious games such as Flower and Journey. Keighley also thought it could be useful to help promising graduates bridge the transition from student to professional. “Joining an established studio isn’t always possible—especially in today’s market—and even then, it isn’t the right path for everyone,” Keighley said. A fellowship, he realized, could give “graduates the time, resources and guidance to pursue a game of their own and not worry about the commercial viability.” As the idea took shape, Cerny also saw an opportunity to enable more games of a certain type: “The target with the grants is games as an artistic medium,” Cerny told me. “We like to say games with ‘artistic, literary and societal value.’” He added: “I’m a pretty big gamer myself, though I tend to gravitate towards the smaller and more unique or artistic titles, games like Neva, Abzu, Gorogoa, Stray or Outer Wilds. I was just playing and Roger on a flight to Japan, and was getting misty eyed to a degree that I was concerned that a flight attendant would ask me if I was OK. “So one fun benefit here is the games that will come out of the Nova Games Foundation – I can’t wait to play them myself.” Cerny believes it will also be useful for Nova fellows to hone their craft and team leadership skills. “We are looking for the next generation of visionaries,” he said. “The trick is that they will also need to have the executive function necessary to drive a small project to completion.” Game File is a reader-supported publication. To receive new posts and support my reporting, please consider becoming a free or paid subscriber. Subscribe Going big with this Keighley and Cerny may have started Nova and may be the ones primarily backing it right now, but they’re dreaming of something that goes beyond them. “Mark and I may have helped get it started, but one of our measures of success is that Nova grows into something the entire games industry feels a sense of ownership in,” Keighley said. “Our ambition is to build a lasting endowment supported by people and companies across the industry, and an equally broad community of creators willing to give their time and experience to the next generation.” The industry has a lot of knowledge that it can pass to the next generation, Keighley said: “Nova can hopefully become a way to connect that generosity with talented young creators at the moment when it can make the biggest difference.” Cerny, who told me he believes Nova can mature “over the next 10 or 20 years,” sees an opportunity to give generations of game makers momentum. “The industry has changed immeasurably since I started in games in 1982,” he said. “These graduates have talent, training and tools that outclass what we had back in the day by an astonishing amount. But they face a tough road ahead getting traction in the industry, and many could benefit from our support. We want to be there to give it to them.” “There’s a personal side to this, too,” Keighley said. “I don’t have children, and I’ve spent a lot of time thinking about what I can do for future generations. Games have been my entire career. I’ve been incredibly fortunate, and helping someone else build a life in this industry feels like a meaningful way to give back.” Cerny’s oeuvre dates back to Marble Madness and Sonic the Hedgehog 2. He has stood on stage multiple times to reveal the future of PlayStation hardware. He’s been an executive producer for a string of modern PlayStation classics such as The Last Guardian and Marvel’s Spider-Man. Nevertheless, of Nova, he said, “It’s certainly not like anything I’ve done before.” Nova Foundation applications will be due in December and the first wave of fellows will be announced in March 2027. A full list of participating universities and steps students and recent graduates can take to apply to become a Nova Fellow is forthcoming.
SKY BLUE CINEMATIX - ENTERTAINMENT - BRAND INTEGRATION : Two Films. One Global Partnership.
London, UK, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Sky Blue Cinematix , the entertainment and brand-integration division of Sky Blue Media Group, to...
Berman campaign: “We’re going fishing” – ER nurse and Democrat Mitchell Berman launches first ad of general election in Wisconsin’s First District Congressional race
Spot features Berman fishing and focuses on ending corruption in Washington, contrasting Berman’s working class background and Republican Bryan Steil’s corporate special interests RAYMOND, Wis. — Today, Mitchell Berman, ER nurse and Democratic candidate for Wisconsin’s First Congressional District, launched...
New business park latest in Painesville’s mounting development
After years of bringing new housing and entertainment options to the Lake County city, moves are now underway to clear the way for industrial and commercial uses.
Sega's President Says There's Been an Increase in Fans Who Don't Play Its Games, But That Doesn't Mean They Aren't Gamers
Sega president and COO Shuji Utsumi says the company has experienced an uptick in fans who don’t actually play the games it develops and publishes.
Gov. Gavin Newsom's former chief of staff seeks to delay sentencing because of health issues
Dana Williamson, Newsom's onetime chief of staff, is seeking to delay her sentencing date for political corruption because of health issues, according to documents.
OM System PEN Camera Pre-Order Available at Amazon US
The upcoming OM System PEN camera is now available for preorder at Amazon US here. OM SYSTEM PEN preorders Product Description OM SYSTEM PEN is a compact interchangeable-lens camera for travel and everyday photography, designed for people who want high image quality and creative flexibility without carrying a bulky kit. At just 393g, its easy-to-carry…
Baptist Health Paducah to offer 'Monday Night Mammograms' during Breast Cancer Awareness Month
Baptist Health Paducah will recognize Breast Cancer Awareness Month by providing Monday Night Mammograms throughout the month of October.
Small business optimism slips in August as sales, inflation concerns persist
Small business optimism declined in August as owners faced weaker sales, inflation and hiring challenges, according to NFIB’s latest survey.
Wisconsin workers see higher wages, fewer jobs, increased disparities
The median wage for Wisconsin workers is $26.17 according to a “State of Working Wisconsin” report. Job growth is slowing as racial disparities trend up.
Amazon Is Taking Preorder Requests for Pokémon TCG 30th Celebration ETBs Well Below Market Price, Marking a Rare First for US Collectors
Amazon US is accepting invite requests for Pokémon TCG 30th Celebration ETBs at $89.99—roughly $90 below market resale value on TCGplayer.
Hunter Biden launching a laptop-themed cryptocurrency
Hunter Biden's $Laptop meme coin launches on Base blockchain, with 20% of tokens going to those who lost money on Trump's $TRUMP crypto coin.
Liverpool’s hunt for a new sporting director: Julian Ward and the standout internal options
FSG president Mike Gordon is leading the search for Richard Hughes' replacement, with both internal and external candidates being considered
Celebrating 19 Years of Impact from One Iconic Desk
For nearly two decades, Administrative Assistant Carolina Rodriguez has been one of the first faces people see and one they remember at South Texas College’s (STC) Mid-Valley Campus. Long before titles or job descriptions, she became something harder to define but easy to feel: a constant presence, a listening ear and the heart of the campus.
Miami Heat's Davion Mitchell Eyeing the Most Improved Player Award
A cryptic beach message signals high ambitions for the Miami Heat’s starting point guard. Surrounded by superstars, Davion Mitchell aims to leverage his facilitating role into a career-defining season.
Speak Up Moore Presents ‘Polls, Politics And Perceptions’ with Donald Bryson
Speak Up Moore will present “Polls, Politics and Perceptions: An Expert Provides Insight into the Minds of NC Voters” on Monday, Sept. 21, from 6-7:30 p.m. at Sandhills Community College,
Where on Earth is safest from global catastrophe?
Researchers have worked out the safest, most resilient country to be in during an apocalyptic event.
Egyptian TV presenter Sarah Khalifa sentenced to death in drug case
Egyptian TV presenter Sarah Khalifa has been sentenced to death for an alleged drug trafficking scheme.
What Formula One Engineering Can Teach Us About AI Infrastructure
Michael Fuller, Executive Chairman of Conflux Technology, examines why thermal performance alone is no longer enough in modern data centers, and how balancing heat transfer with hydraulic efficiency can unlock significant operational gains. The AI era is forcing data center operators to rethink some long-held assumptions about infrastructure design. As processor power densities continue to […]
Norman Rock Creek Entertainment District faces lawsuit over tax increment financing
Norman's Rock Creek Entertainment District is a $1 billion project set to open in 2028, including a multipurpose performance venue, restaurants, retail space, office development, a hotel, and multiple housing options.
The US wants a stronger battery supply chain. China has a decades-long head start
The Trump administration is attempting to strengthen the U.S. battery supply chain and reduce the country’s dependence on China, but analysts and industry executives say current funding is small compared with what would be needed to substantially challenge China’s dominance, CNBC reports. In August 2026, the Department of Energy awarded $500 million to seven companies […]
Louisiana concrete companies join forces to capitalize on construction boom
Two Louisiana concrete suppliers are joining forces with two out-of-state companies to pursue large-scale construction projects as billions of dollars in new industrial and technology investment move … Already an INSIDER? Sign in. Already an INSIDER? Sign in
Roundup: Energy employment / Small business confidence / Maritime woes
Jobs in transition: Energy sector employment fell about 1% nationwide and in Louisiana from 2024 to 2025, with Louisiana losing 1,131 jobs to reach roughly 160,000 workers. The decline was driven largely by automation, policy changes affecting renewable energy, and shifting economics, while traditional energy industries such as coal and nuclear saw job growth. Despite […]
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Trump’s Bombardier threat puts aerospace supply chain at risk
U.S. President Donald Trump has threatened to ban the sale of aircraft from Canada’s Bombardier unless it manufactures planes in the U.S. In response, the maker of private jets noted that many components for its planes, including the wings, are produced in the U.S. and its supply chain relies heavily on U.S. companies. Since Canada-U.S. […]
How Is Hilton Worldwide's Stock Performance Compared to Other Leisure and Entertainment Stocks?
Hilton Worldwide has outperformed the Leisure and Entertainment industry over the past year, and analysts are cautiously optimistic about the stock’s prospects.
Corning Stock Climbs On Multibillion-Dollar Verizon Network Deal
Corning stock rose after the provider of optical communications gear for telecom networks announced a multi-billion agreement with Verizon.
The New York Times
Seven of Ukraine’s top 10 military contractors won new business despite open criminal investigations for fraud, failures to deliver on earlier deals or the arrest of chief executives for corruption,...
LMH Health announces participation in Astra Health to expand access, improve care and reduce healthcare costs
We are pleased to announce that LMH Health is one of five independent Kansas health systems joining together to form Astra Health, a new regional healthcare collaboration designed to improve patient care, strengthen access to specialty services, and deliver more affordable healthcare options for employers and communities across Kansas. By working together, participating health systems […]
Six decades of politics (but little government)
The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share
Hormuz disruptions hitting small businesses hardest, UN trade agency warns
GENEVA, Sept 8 (Reuters) - Disruptions in the Strait of Hormuz could push small and medium-sized businesses out of global supply chains, increasing economic concentration and weakening the resilience
Hormuz disruptions hitting small businesses hardest, UN trade agency warns
GENEVA, Sept 8 (Reuters) - Disruptions in the Strait of Hormuz could push small and medium-sized businesses out of global supply chains, increasing economic concentration and weakening the resilience
‘Star Trek’ and NASA have intertwined legacies – the show championed diversity and inspired generations of real space scientists
60 years of ‘Star Trek’: A cultural anthropologist on how the show’s “infinite diversity in infinite combinations” conception helped shape NASA’s vision of the future.
Optimi Health to Participate in the H.C. Wainwright 28th Annual Global Investment Conference
VANCOUVER, British Columbia, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Optimi Health Corp. (Nasdaq: OPTH) (CSE: OPTI) (“Optimi” or the “Company”), a commercial-stage pharmaceutical manufacturer of regulated psychedelic drug products, today announced that it will participate in the H.C. Wainwright 28th Annual Global Investment Conference. The conference will be held September 14-16, 2026, at the Lotte New York Palace Hotel. A Company presentation will be available on demand here beginning Friday, Septem