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Michael McCarthy Considering Three Races As Options For Journalism's Return
After Journalism worked five furlongs in company Sunday at Santa Anita, trainer Michael McCarthy said he is looking at three potential races to kick off the colt’s 4-year-old campaign. Journalism could return in either the Oaklawn Handicap (G2) or Ben Ali (G3) at Keeneland, both on April 18, or ...
Two Offseason Trades Patriots Should Have Made But Didn't
Here are two trades that the New England Patriots should have pursued this offseason but ultimately passed on.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
The Boston Celtics are terrifying to their opponents again
Instead of mailing it in for a season, the Celtics have rebuilt themselves into a contender again against all odds.
Breaking down Bills’ selections in latest NFL mock drafts
According to the latest NFL mock drafts, the Bills could go wide receiver, linebacker, safety, or defensive linemen at pick 26.
Chiefs’ 2026 NFL Mock Draft roundup after NFL Free Agency
A closer look at the Chiefs’ 2026 mock draft outlook after free agency, with linked to edge help, cornerback, and offensive line support.
Bucs facing a tough decision with Baker Mayfield in 2026
The Bucs have to get the contract situation with Baker Mayfield solved sooner rather than later.
NFL Network: What's next for Bills QB Josh Allen? (video)
NFL Network roundtable looks ahead to Josh Allen and the Bills in 2026.
Titans sign ex-Browns linebacker
The Titans have signed former Browns linebacker Mohamoud Diabate to a contract after he wasn't tendered as an RFA.
This floating time crystal breaks Newton’s third law of motion
Scientists have created a new kind of time crystal using sound waves to levitate tiny beads in mid-air. These particles interact in a one-sided, unbalanced way, breaking the usual rules of motion and creating a steady, repeating rhythm. The system is surprisingly simple yet reveals complex physics with big implications. It could help advance quantum computing and deepen our understanding of biological timing systems.
Chicago Cubs news and notes
#Cubs, #MLB, and #MiLB news.
I left Goldman Sachs to build a small baking business. Here's how my time at the firm is giving me a leg up.
Pompey's hopes of staying up now unsure
BBC Radio Solent commentator Andrew Moon gives his thoughts following Portsmouth's 6-1 defeat at Queens Park Rangers in the Championship.
NFL draft injury analysis: Caleb Downs, S
Caleb Downs medical report
Game Preview: Carolina Hurricanes @ Pittsburgh Penguins 3/22/2026
Who: Carolina Hurricanes (44-19-6, 94 points, 1st place Metropolitan Division) @ Pittsburgh Penguins (35-18-16, 86 points, 2nd place Metropolitan Division) When: 3:00 p.m. eastern How to Watch: Locally broadcast on Sportsnet Pittsburgh and FDSN South, streaming on ESPN+ Pens’ Path Ahead: Quality opponents await in the next week; the Pens host Colorado on Tuesday, an Avs team […]
Scouting Future Saints: Washington wide receiver Denzel Boston
Denzel Boston might not be the most popular name among receivers in the draft, but he's among the most talented and he could fit what the Saints need.
What time is Michigan women's basketball's second round game?
Michigan cruised to a blowout victory over Holy Cross in their opening NCAA Women's Tournament matchup. See who they play next.
49ers News: 25 more Sundays until NFL football is back
Your daily San Francisco 49ers news for Sunday, March 22nd, 2026
Warriors drop third straight with 126-110 loss vs. Hawks
The Warriors had no answer for Dyson Daniels, CJ McCollumn and the Hawks on Saturday in a 126-110 loss.
Businesses worried as fuel prices rise
An increase in fuel prices amidst the US-Israel war with Iran is affecting businesses in the UK.
Chivas hold off Monterrey’s comeback to get another win
Chivas defeated Monterrey by a 3-0 score in match defined by the last play of the match.
Jacob Devaney: Man United loanee puts in midfield masterclass
Manchester United had six players in loan action on Saturday afternoon.To find out where all of Manchester United’s loanees are plying their trade this season, click hereEthan EnnisEnnis played the ...
Can Manchester City's Guehi play in EFL Cup final?
Manchester City will be without a key defender for Sunday's final at Wembley against Arsenal.
'Heartbreaking' - fighter pay debate laid bare at UFC London
The debate around fighter pay reemerges at UFC London amid some career-defining performances on the undercard.
OPEN THREAD
The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Gameday!! Huge clash in the context […]
Europe’s trade with Iran: Which countries do the most business with Tehran?
EU–Iran trade fell to its lowest level in two decades in 2025 due to sanctions. Trade continues on a limited scale, with Germany accounting for the largest share.View on euronews
Anders Lee defends Islanders’ effort after blowout Canadiens loss
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Arizona softball walks off ASU to even series
Arizona softball earned a walk-off win over ASU Saturday night, though not the kind the Wildcats may have been expecting through the first part of the game. Arizona jumped out to an 8-0 lead, then allowed the Sun Devils to claw all the way back before Regan Shockey delivered a walk-off single in the seventh […]
Nebraska survives near-miracle heave at buzzer to advance past Vanderbilt, keep dream season alive in thriller
GALLERY: Moments from Iowa State’s 9-7 win over Houston
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Colts Reacts Survey Results
How are you feeling, Colts fans?
Luka Doncic Explains Controversial Exchange with Goga Bitadze Before Suspension
Luka Doncic did not let up on Saturday night, leading the Los Angeles Lakers to a 105-104 win over the Orlando Magic. Doncic has been on an absolute heater of late, and he kept his foot on the gas against the Magic. The Lakers improved to 46-25 and remain third in the Western Conference.
Eddie Hall Teases Summer MMA Return, Dillon Danis Fight
Former World's Strongest Man Eddie Hall is eyeing a return to the cage later this year, and wants to face Dillon Danis.
Another Illinois basketball player enters legendary status in NCAA tournament
The Illinois basketball team has had some incredible performances this season, and one player just put up an amazing Round of 32 showing against VCU.
5 incredible observations from the Illinois basketball win over VCU
Illinois basketball continued their trek in the NCAA tournament with a huge win over VCU on Saturday night.
Lakers player grades: Luke Kennard gives L.A. ninth straight win
The Lakers defeated the Magic for their ninth straight win thanks to Luke Kennard's heroics at the end of the game.
Texas turns key weakness into strength in upset of Gonzaga
Texas overcame early interior struggles to beat Gonzaga 74-68 and reach the Sweet 16. Four Longhorns scored in double figures in Sean Miller's first season.
Arizona Cardinals GM perhaps gave hint about Michael Wilson's future
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Warriors' Stephen Curry set for major checkpoint in injury recovery
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Kings fall 4-1 to Sabres amidst playoff push
The Los Angeles Kings fall short to the Buffalo Sabres in a 4-1 loss Saturday at Crypto.com Arena. Artemi Panarin would score the Kings' lonesome goal, but it was no match for Buffalo's four goals by four different skaters. The Kings stand in the third place Wild Card spot at 28-25-16 and 72 points.
Washington Football Hires Utah State Analyst as Special Teams Analyst
Washington will once again have two coaches working on specials teams in 2026 after added a rising analyst to work alongside Chris Petrilli.
Movsar Evloev vs. Lerone Murphy full fight video highlights
Movsar Evloev wins close call against Lerone Murphy at UFC London
Warriors provide exciting injury update on Moses Moody
The Golden State Warriors have provided an exciting injury update on Moses Moody
Dustin Baker’s 2026 Vikings Mock Draft 3.0 Has Arrived
The Vikings shook operations up just a bit during free agency, notably adding quarterback Kyler Murray and CB3 James Pierre, […]
Four-star forward Joe Philon commits to UCLA
Joe Philon, a four-star power forward in the 2026 class, has committed to UCLA, he told On3. The 6-foot-8 senior out of Montverde Academy (FL) chose the Bruins after considering Ohio State, South Florida, UNLV, and Xavier. Philon, a native of Tampa, Florida, is the No. 56 overall player in the 2026 class, according to […]
"Derby of the dead child": This match changed football forever
When does a game become legendary? Is it when everyone can remember where they were at the time of the match? When the game has its own Wikipedia article? When the game marks a turning point in footba...
UFC London live blog: Movsar Evloev vs. Lerone Murphy
Follow along for live updates on Movsar Evloev vs. Lerone Murphy at UFC London
Seiya Suzuki will not be ready for Opening Day
This is not good news.
Islanders @ Canadiens [Game #70 thread]
The Islanders have a big one tonight in Montreal, where the Canadiens are in a three-way tie for the Atlantic’s third playoff spots (84 points, same as wild card occupants Detroit and Boston but with a game in hand) while the Islanders begin a night of play on the outside looking in for the first […]
Donovan Mitchell returns against New Orleans
Donovan Mitchell returns against New Orleans
Newly formed Eastside Business Association holds first meeting
The newly formed Eastside Business Association held its first meeting today.
What’s Going on Here?
Wentz Signing Raises More Questions
Cowboys land top pass rusher in new mock draft
It feels inevitable that Dallas will take a pass rusher in the first round.
Queens small businesses push for stronger safety measures after attempted robberies
QUEENS, N.Y. (PIX11) — Business owners in Queens are calling for stronger public safety measures after an attempted break-in at one of Woodhaven’s most well-known landmarks. The incident happened earl...
Third-round draft prospects who can really help the Cowboys
Who do you want Dallas to draft with pick 92?
UFC London’s Felipe Franco promises entertainment after teammate Jailton Almeida’s release: ‘They want to see blood’
Felipe Franco battles undefeated Mario Pinto at UFC London
Physicists created an electron 'catapult' that moves particles at 'extraordinary' speed
Using a new method, physicists found a way to 'catapult' electrons across solar materials in quadrillionths of a second.
Skin therapy business opening with celebration next month in the Poconos
The new location will offer customized skin rejuvenation treatments, including advanced exfoliation, LED light therapy, and modern facial technologies.
Former Dallas Cowboys wide receiver announces retirement from the NFL
A former Dallas Cowboys wide receiver who spent one season with the team and 10 more with the Indianapolis Colts have announced his retirement from the NFL.
Science news this week: Super El Niño looms, an Acropolis marble fragment resurfaces, and a pure hexagonal diamond is born
March 21, 2026: Our weekly roundup of the latest science in the news, as well as a few fascinating articles to keep you entertained over the weekend.
Denver Broncos mock draft: Post-Jaylen Waddle trade
We’re coming back to the mock draft simulator this weekend. The Denver Broncos said ‘f dem picks’ and acquired wide receiver Jaylen Waddle from the Miami Dolphins this week. That trade provided a big boost to the offense, but it will make their 2026 NFL Draft much more challenging. With the reduction in draft capital, […]
Video reviews to be introduced at Wimbledon
Video review technology will be introduced at Wimbledon for the first time this year.
This tool puts ChatGPT, Gemini, Grok, and more AI models in one place
Stop wasting time switching tabs.
Vaz and Tsimikas to start vs Lecce
Good attacking depth and a knack for jostling opponents. Plus, an assist and a penalty won. It may not have been enough to eliminate Bologna from the Europa League, but it might have been enough to co...
Today’s Papers – Italy’s World Cup mission, Napoli’s comeback
La Gazzetta dello SportBeware Inter, Conte returnsNapoli go -6. Cagliari beaten 1-0. Chivu to the attack tomorrow in FlorenceMilan-Toro, Leao is outSan Siro. Allegri for the comeback with Fullkrug and...
Your 2026 NCAA Basketball Tournament Viewing Guide: March 21, 2026
Bummed about only one men’s tournament game at a time for 6 hours today? THAT’S WHAT THE WOMEN’S TOURNAMENT IS FOR!
🗞️Today's headlines: Joan García, academy talent and much more
The call from Luis de la Fuente to Barça’s goalkeeper is one of the top stories of the day on this football-filled Saturday.A great weekend is approaching ahead of an international break, where the...
Thousands of runners gear up for half marathon
Road closures will be in place for town's half marathon, with thousands expected to line the route.
Jack Draper blown away in ‘difficult’ Miami Open exit
The giant Opelka fired down 25 aces and 47 winners in two tiebreak sets, winning 7-6 (3) 7-6 (0), as Draper suffered a second-round exit
Nebraska lands the commitment of 3-star athlete Kaden Howard
The feel-good momentum surrounding the Nebraska athletic department continues to build following the men’s basketball team’s first-round NCAA Tournament victory—and it’s now carrying over onto the recruiting trail. The Cornhuskers have secured a commitment from 3-star athlete Kaden Howard, a 5-foot-10, 160-pound playmaker out of Miami, Florida. Howard picked Nebraska over Louisville, West Virginia and […]
Tottenham eye transfer move for Freiburg’s Noah Atubolu
Tottenham Hotspur have watched Freiburg’s Noah Atubolu as they search for goalkeeping reinforcements this summer, according to the Daily Mail.Tottenham need a new goalkeeper, with Guglielmo Vicario ...
Wine vs beer vs spirits: Which is the least bad for your health?
A study of 340,000 adults suggests not all alcohol carries the same risk - even at low to moderate levels, beer, cider and spirits were linked to higher mortality, while wine was associated with a lower risk.
Commanders' LB's brother is a March Madness hero for Kentucky
What a month for the Oweh family.
Diamondbacks 8, Brewers 7: Hot Temps, Hotter Bats
Zac Gallen got roughed up in his final Spring outing, but the bullpen and offense earned a W.
In Opening Day preview, Mariners thrash Guardians, 20-8
Mariners smoke six homers en route to big win; Cole Young goes yard twice and Dominic Canzone hits a grand slam
Braves News: Rowdy Tellez signing, roster cuts, and more
Atlanta Braves news and notes from Friday.
Yankees news: Optimism at shortstop
2026 looks promising at shortstop; Carlos Lagrange was electric this spring; Michael Kay defends Judge
Brewers top Mariners in Spring Breakout matchup
Luis Peña homers, four others double in prospect showcase
Steelers re-sign versatile veteran offensive lineman
The Pittsburgh Steelers have re-signed offensive lineman Ryan McCollum to a one-year contract, the team announced on Friday.
Lakers release injury report for Saturday's game versus Magic
One of the Lakers' three stars could miss Saturday's game against the Magic.
Arizona Cardinals sign former Titans OL Uli Udoh
The Cardinals signed a fourth free agent offensive lineman with positional versatility and starting experience.
Devils' win streak snapped with 2-1 loss to Capitals
Logan Thompson made 30 saves, losing his shutout bid with just 43 seconds remaining, and the Washington Capitals beat the New Jersey Devils 2-1 on Friday night.
Former Rams 5th-round edge rusher signing with Panthers
Former Rams OLB Nick Hampton, who was a fifth-round pick in 2023, is signing with the Panthers.
Eagles Predicted to Make Perfect Selection in 2026 NFL Draft
The Philadelphia Eagles have had a nice offseason and that should only continue in the NFL Draft.
Full circle: Sean McVay collecting former players on coaching staff
Robert Woods joins Brian Allen on Sean McVay’s Rams coaching staff
Braves sign Rowdy Tellez to MiLB deal, per report
Atlanta add another veteran left-handed hitting first base/designated hitter option late in camp.
Salary cap: OL Elgton Jenkins’ contract with the Cleveland Browns
Looking at the details of Browns OL Elgton Jenkins’ contract, option bonuses, and incentives.
Bengals hold top-30 visit with Rutgers QB Athan Kaliakmanis
Cincinnati wants a promising developmental quarterback behind Joe Burrow, and they had a visit with one recently.
Report: Panthers agree to terms with local free-agent LB
The Panthers are reportedly signing an Anderson, S.C. native and former All-Sun Belt selection.
Spring Game #28: Athletics versus Cubs Game Thread
Ready for some Friday night baseball?
Small business and entrepreneurship growth a point of focus for Secretary of State’s Office
LEWISBURG, WV (WVNS) – Entrepreneurs and small business owners in the Mountain State have gotten some extra support with the passage of new legislation. West Virginia Secretary of State Kris Warner me...
Cowboys post-free agency 7-round mock draft
What is your favorite type of mock so far for the Cowboys?
Charleston Waterkeeper opens Community Science Lab for researching water quality, monitoring microplastics
CHARLESTON, S.C. (WBCD) — Charleston Waterkeeper has opened a first-of-its-kind Community Science Lab, inviting residents, students, and volunteers to take a hands-on role in monitoring Lowcountry wat...
The Best Early Amazon Big Spring Sale Apple Deals We've Found So Far
You can save $100 on the flagship Apple Watch Series 11, plus pick up an Apple MacBook Pro for $200 less, and that's even before Amazon's seasonal sale begins on March 25.
