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Results for " L.A " 428 found 🔀 AI-powered Shuffle

Garry's Mod Successor Faces Flood Of AI Slop On Steam

Also: is L.A. Noire 2 still on the table?

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Apr 28 • 3:31 PM EDT • Technology • kotaku.com
Student hospitalized after suffering burns during science project at MAST Academy in Key Biscayne - WSVN 7News | Miami News, Weather, Sports

KEY BISCAYNE, FLA. (WSVN) - A science experiment gone wrong sent one student to the hospital.According to school officials, a female MAST Academy student sufferedRead More

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Apr 27 • 4:42 PM EDT • Science • wsvn.com
Rodgers and Hammerstein, Lerner and Loewe musicals come to L.A.

Rodgers and Hammerstein's "Flower Drum Song" and "The Sound of Music" and Lerner and Loewe's "Brigadoon" are all running in L.A. this spring.

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Apr 27 • 6:00 AM EDT • Entertainment • latimes.com
Letters to the Editor: Transactional leadership has its place in business, but not in war

'Let me suggest that, instead, a transformational leadership style that builds on knowledge, ideas, motivation and experience, among other attributes, to form results that will last beyond Band-Aid transactions that simply cover scabs,' writes an L.A. Times reader.

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Apr 24 • 8:00 AM EDT • Business • latimes.com
Potential 2028 presidential candidates gather in L.A. for Democratic fundraiser

Democratic governors, some eyeing 2028 presidential bids, gathered in Los Angeles for a big-dollar party fundraiser.

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Apr 24 • 6:00 AM EDT • Politics • latimes.com
Bass, Barger meets with Trump to push for L.A. fire recovery funds

The mayor and county supervisor said they had a "high-level discussion" with the president, sharing stories about what fire survivors are experiencing day to day.

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Apr 22 • 9:54 PM EDT • Politics • latimes.com
Rockets-Lakers takeaways: How did L.A. make Kevin Durant disappear to claim 2-0 series lead?
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Apr 22 • 2:22 AM EDT • Sports • sports.yahoo.com
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Is Netflix Making a Big Real Estate Move In L.A.?

The streaming giant is reportedly in talks to acquired the Radford Studio Center.

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Apr 21 • 7:35 PM EDT • Business • hollywoodreporter.com
FBI probes missing or dead scientists, including four from the L.A. area

President Trump told reporters last week that he had been briefed on the missing and dead scientists, which he described as “pretty serious stuff.”

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Apr 21 • 5:15 PM EDT • Science • latimes.com
Registered Nurses, Customer Service Representatives and Retail Salespersons are the Top Jobs in February - Alabama Department of Labor

PRESS RELEASE FOR IMMEDIATE RELEASE: APRIL 21, 2026 Registered Nurses, Customer Service Representatives and Retail Salespersons are the Top Jobs in February MONTGOMERY - Data collected and analyzed by the Alabama Department of Workforce’s Labor Market Information (LMI) Division shows that in February 2026, there were 104,060 job ads posted in Alabama, representing a monthly increase of […]

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Apr 21 • 12:04 PM EDT • Health • adol.alabama.gov
L.A. must be proactive to keep its business opportunities

'Wake up, City Hall! Empower and respect your agencies that enforce basic laws that keep our streets clean and safe,' writes an L.A. Times reader.

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Apr 21 • 8:30 AM EDT • Business • latimes.com
Christina Applegate shares health update after reported hospital visit

Christina Applegate is thanking fans and friends for their well wishes after the 'Dead to Me' star was reported to be hospitalized in L.A.

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Apr 20 • 3:22 PM EDT • Health • latimes.com
Chargers GM makes defiant statement on WR trade rumors

It is clear L.A. has zero interest in moving on.

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Apr 16 • 7:49 PM EDT • Sports • sports.yahoo.com
Coachella 2026: We talked to L.A.'s beloved Bob Baker Marionettes about the festival

The Bob Baker Marionettes made their Coachella Valley Music and Arts Festival debut on April 10.

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Apr 16 • 3:56 PM EDT • Entertainment • latimes.com
L.A. County District Attorney’s Office Investigating Swalwell Allegations
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Apr 16 • 1:17 AM EDT • Politics • cnn.com
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The history of popes and politics

Today on AirTalk: Popes and politics; L.A. City Charter reform proposals; Doing things alone; Will Gen Z save moviegoing? A chimpanzee civil war? and…

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Apr 15 • 11:51 AM EDT • Politics • laist.com
City and Olympic boss joust over who gets big Games contracts

Your morning catch-up: L.A. officials want more business from 2028 Olympic committee, another woman accused Swalwell of assault and more big stories

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Apr 15 • 9:30 AM EDT • Business • latimes.com
LA Times Festival of Books: What to know about tickets, parking, speakers

Here's everything you need to know about tickets, parking and speakers ahead of the L.A. Times Festival of Books this weekend.

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Apr 15 • 6:00 AM EDT • Entertainment • latimes.com
L.A. Times readers celebrate UCLA women's basketball's title win

Times readers cheer UCLA coach Cori Close and players Gabriela Jaquez, Kiki Rice, Lauren Betts, Gianne Kneepkens, Angela Dugalic and Charlisse Leger-Walker.

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Apr 11 • 3:12 PM EDT • Sports • latimes.com
Lakers, LeBron James best Suns to clinch home court advantage

LeBron James continued his brilliance with another vintage performance for L.A. to clinch home court.

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Apr 11 • 3:02 AM EDT • Sports • sports.yahoo.com
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Letters to the Editor: Anyone with political aspirations should be fighting to stop Trump

'Everyone knows President Trump is out of control, and yet Congress and the Supreme Court sit back and watch as we circle the drain,' writes an L.A. Times reader.

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Apr 10 • 10:00 AM EDT • Politics • latimes.com
A year later, L.A.B. Golf’s weird science got bigger … and more personal

L.A.B. Golf shakes up the putter game with zero-torque tech and wild customization—find one that fits your style and reshapes your game today!

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Apr 10 • 6:45 AM EDT • Science • popsci.com
Trump Administration Investigating L.A. Schools’ Gender Disclosure Policies

The investigation into the nation’s second-largest school district was prompted by a lawsuit from parents who say the policies contributed to their child’s death.

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Apr 8 • 4:24 PM EDT • Politics • nytimes.com
L.A. election shadow hearing: Democrats, experts defend voting systems

House Democrats gathered in Los Angeles on Tuesday for a "shadow hearing" on midterm election security, where experts echoed their arguments that state-run elections are safe and secure.

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Apr 7 • 7:47 PM EDT • Politics • latimes.com
2 CSU Campuses Receive $77M to Support Mental Health in L.A.

The Ballmer Group has donated $77 million to two California State University campuses to improve mental health services in the Los Angeles area.

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Apr 6 • 8:00 PM EDT • Health • insidehighered.com
UCLA, CSUs receive $110-million donation for mental health

UCLA, Cal State L.A. and Cal State Dominguez Hills have received $110 million from the Ballmer Group to train more students for mental health careers in California.

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Apr 6 • 1:00 PM EDT • Health • latimes.com
Jennie Garth and Daughter Lola Volunteer in L.A. Ahead of Easter Weekend, Plus Jaafar Jackson, Zendaya and More

Jennie Garth and Daughter Lola volunteer in L.A. ahead of Easter Weekend, Plus Jaafar Jackson, Zendaya and More. From Los Angeles to New York City, and everywhere in between, see what your favorite stars are up to.

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Apr 4 • 6:00 AM EDT • Entertainment • people.com
Trump's budget singles out L.A. homelessness agency as he proposes housing cuts

Trump’s proposed budget attacks L.A.'s homelessness agency in push to eliminate a federal program that funds housing and services for homeless Americans.

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Apr 3 • 5:47 PM EDT • Politics • latimes.com
L.A. LIVE, SEGA Partnership Aims to Blend Gaming With Live Entertainment

SEGA and L.A. LIVE have announced a strategic partnership to integrate gaming into one of Los Angeles’ premier entertainment districts.

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Apr 1 • 12:13 PM EDT • Entertainment • yahoo.com
L.A. festival helps the trans community heal through comedy

At The Joy Who Lived festival, trans comedians and actors can shine under spotlights created by and for trans creatives.

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Apr 1 • 6:00 AM EDT • Entertainment • latimes.com
First Entertainment CU Carved Out a Lucrative Niche Serving the L.A. Market. How It's Taking Its Show on the Road

Building on its industry smarts, the L.A lender to the film industry's people launches all-digital 'CineFi' to serve Atlanta, 'Hollywood of the South.'

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Mar 31 • 1:29 PM EDT • Entertainment • thefinancialbrand.com
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Paul McCartney at the Fonda: a rock legend in thrilling close-up

The 83-year-old rock legend did his latest underplay at L.A.'s Fonda Theatre on Friday night.

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Mar 28 • 6:34 PM EDT • Entertainment • latimes.com
Letters to Sports: Bill Plaschke's Dodgers prediction is a winner

Readers of the L.A. Times Sports section give their thoughts on the Dodgers and Bill Plaschke's prediction they won't win another World Series (hint, they like it).

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Mar 28 • 7:00 AM EDT • Sports • latimes.com
The L.A. Phil premieres Gerald Barry’s wacky ‘Salome’

Following two of the most brilliantly wacky operas of our time from Gerald Barry, the premiere of his 'Salome' promises to out-wacky the others.

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Mar 27 • 5:19 PM EDT • Entertainment • latimes.com
The Oscars are leaving Hollywood in 2029, ending long run at Dolby Theatre

The Academy Awards will move from the Dolby Theatre, their home for nearly a quarter century, to L.A. Live in downtown Los Angeles

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Mar 27 • 9:57 AM EDT • Entertainment • detroitnews.com
UABTeach Program Achieves Record Retention and Largest Math & Science Teaching Cohort - Alabama Department of Labor

FOR IMMEDIATE RELEASE March 26, 2026 BIRMINGHAM, Ala. – The UABTeach program at the University of Alabama at Birmingham, supported by The Alabama STEM Council via the Alabama Department of Workforce, is reporting strong student retention with a record number of STEM majors progressing toward graduation with the additional bonus of earning their teacher certifications. […]

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Mar 26 • 5:53 PM EDT • Science • adol.alabama.gov
Trump says he wants to send federalized troops to L.A., San Francisco

Trump called on the mayors and governors of several blue cities and states to allow troops to 'come in and stop the crime,' and specifically called out Los Angeles and San Francisco.

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Mar 26 • 5:43 PM EDT • Politics • latimes.com
The Oscars are leaving Hollywood

In 2029, the Oscars will move from the Dolby Theater in the heart of Hollywood to the Peacock Theater at L.A. Live, a sprawling tourist hub in Downtown Los Angeles,

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Mar 26 • 3:50 PM EDT • Entertainment • wxow.com
Pulitzer winner 'Fairview' is a little cloudy in its L.A. premiere

Jackie Sibblies Drury's Pulitzer Prize-winning drama "Fairview" receives its L.A. premiere at the Matrix in a Rogue Machine production directed by Oz Scott.

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Mar 25 • 6:00 AM EDT • Entertainment • latimes.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Lakers player grades: Luke Kennard gives L.A. ninth straight win

The Lakers defeated the Magic for their ninth straight win thanks to Luke Kennard's heroics at the end of the game.

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Mar 21 • 10:29 PM EDT • Sports • sports.yahoo.com
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Downtown Chico business owner voices concerns over street closures for events

A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });

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Mar 20 • 8:45 PM EDT • Business • actionnewsnow.com
Philadelphia Eagles' dynamic duo named one of NFL's best

The Philadelphia Eagles' dynamic receiving duo of A.J. Brown and DeVonta Smith was recently named one of the best in the entire NFL by Moe Moton of Bleacher Report. The pairing of Smith and Brown was named as the fifth-best wide receiver duo in the league, behind Ja'Marr Chase and Tee Higgins in Cincinnati, Puka Nacua And Davante Adams in L.A., CeeDee Lamb and George Pickens in Dallas and Amon-Ra St. Brown and Jameson Williams in Detroit.

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Mar 18 • 10:08 PM EDT • Sports • sports.yahoo.com
Health officials urge consumers to avoid raw cheddar tied to ongoing E. coli outbreak

L.A. County health officials are urging consumers not to eat Raw Farm-branded raw cheddar cheese after the product was linked to an ongoing outbreak of Shiga toxin‑producing E. coli. This type of b…

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Mar 17 • 5:42 PM EDT • Health • ktla.com
Geffen Playhouse 2026-27 season: world and L.A. premieres

Geffen Playhouse Artistic Director Tarell Alvin McCraney aims to deliver 'world-class theater at your friendly neighborhood playhouse.'

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Mar 17 • 8:00 AM EDT • Entertainment • latimes.com
Downtown L.A. needs retail resuscitation. San Francisco's subsidized shops offer a solution

DTLA needs S.F.’s retail resuscitation secret: subsidized pop-ups

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Mar 16 • 6:00 AM EDT • Business • latimes.com
‘I loved it because I love writing’: Student filmmakers, animators strive for a spot in L.A.’s entertainment industry

Hollywood High prepares students for a career in visual media.

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Mar 15 • 8:00 PM EDT • Entertainment • edsource.org
For Patients Behind on Rent, L.A. Health Center Provides a Lifeline

St. John’s Community Health Center is tackling Los Angeles’ housing crisis by connecting patients to vital rental assistance.

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Mar 11 • 6:16 AM EDT • Health • directrelief.org
Reckoning With State and Federal Cuts, L.A. Safety-Net Clinics Push for a New Tax

By Bernard J. Wolfson | KFF Health News LOS ANGELES — Mia Angulo, who is pregnant and due in May, is living in a tent with her boyfriend in the predominantly Latino neighborhood of Boyle Heights. Lingering pain from a car crash two months ago, on top of an already hardscrabble life, has Angulo ...

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Mar 9 • 4:29 PM EDT • Health • usnews.com
LA is known for its beautiful sunlight. Scientists call it pollution

It’s Daylight Saving, that time of the year when we get more of that gorgeous L.A. light. To scientists, it’s a bit more complicated.

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Mar 8 • 8:00 AM EDT • Science • laist.com
Letters to the Editor: A free market inherently doesn’t work when it comes to healthcare

'Providers are required by law to treat patients, and sick or injured people are hardly in a position to walk away if the treatment is a little more costly than they would like,' writes an L.A. Times reader.

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Mar 7 • 6:07 AM EST • Health • latimes.com
L.A. County transforms vacant buildings into ‘mental health treatment village’

Los Angeles County leaders are breaking ground Friday on a new mental health treatment complex that will transform long-vacant buildings on a historic Norwalk hospital campus into a “village” for c…

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Mar 6 • 12:27 PM EST • Health • ktla.com
Novak Djokovic's L.A. sports tour: LeBron James, Luka Doncic, UCLA football

Ahead of the BNP Paribas Open, which he is attempting to win for a sixth time, the former world No. 1 was happy to just be a fan.

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Mar 4 • 3:45 PM EST • Sports • tennis.com
Rams mock draft roundup: L.A. picks Matthew Stafford's heir at QB

With the NFL combine over and free agency a week away, see what experts are saying about LA's two first round picks in the latest mock draft roundup.

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Mar 4 • 6:27 AM EST • Sports • usatoday.com
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L.A. cannabis businesses owe $400 million. The city may get only $30 million

Based on a projection that about half of eligible cannabis businesses would take part in the program, the city would collect about $30 million in back taxes while waiving about $25 million in penalties.

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Mar 4 • 6:00 AM EST • Business • latimes.com
There were 13 full-service public health clinics in L.A. County. Now there are 6

On Feb. 27, the L.A. County Department of Public Health eliminated services at six of its 13 free clinics, citing funding cuts at the federal, state and local levels.

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Mar 3 • 6:00 AM EST • Health • latimes.com
Bears, B.L.A.C.C. Employee Resource Group lead Black in Sports Panel

For a third consecutive year in honor of Black History Month, the Chicago Bears hosted a “Black in Sports” panel conversation, providing Black professionals from across the organization an opportunity to share personal experiences, career insights and vis

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Feb 27 • 11:40 AM EST • Sports • chicagobears.com
Rhode Island health officials report second blizzard-related death

Rhode Island Department of Health on Wednesday announced a second blizzard-related death after record-breaking snowfall.A DOH spokesperson said it was a shoveli

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Feb 25 • 5:45 PM EST • Health • turnto10.com
Letters to the Editor: I’ve received healthcare all over the world. The worst was in the U.S.

'Next time I need dental work, I'll fly to Buenos Aires, have my crown put on, stay a month, enjoy the malbec and I'll be money ahead,' writes an L.A. Times reader.

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Feb 25 • 8:00 AM EST • Health • latimes.com
LeBron James' buzzer beater misses as Lakers fall to Magic

The Lakers come up short when LeBron James misses a last-second shot that sends L.A. to a 110-109 loss to the Magic.

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Feb 25 • 1:16 AM EST • Sports • sports.yahoo.com
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Erin Wright’s Hyperreal Paintings Make Luxury Living Weird

Rising L.A. painter Erin Wright subtly critiques the glamour of the perfect home.

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Feb 24 • 11:57 AM EST • Technology • artsy.net
How an Aging California Is Turning to Senior Centers for Romance, Community and Health

No two senior centers are alike. We visited three very different venues in L.A. to learn how they’re changing for California’s aging population.

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Feb 22 • 3:00 PM EST • Health • kqed.org
L.A. County health officials confirm fourth case of measles in person who traveled to LAX, other locations

Los Angeles County health officials on Thursday confirmed a case of measles in a person who recently traveled internationally and visited several public locations in Los Angeles County while infect…

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Feb 20 • 4:05 PM EST • Health • ktla.com
Married L.A. County couple charged with operating large-scale sex services business

A married couple in Los Angeles County was arrested and charged with allegedly owning and operating a large-scale online sex services business. The suspects were identified as Kebin Dong, 38, and W…

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Feb 19 • 11:06 PM EST • Business • ktla.com
Meta ‘cannot pretend’ social media is not addictive, political commentator says

L.A. Mom Magazine founder Shirin Yadegar and political commentator Debra Lea discuss Meta CEO Mark Zuckerberg testifying in a landmark trial and leadership changes at CBS on ‘Fox News @ Night.’

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Feb 18 • 11:32 PM EST • Politics • foxnews.com
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Daniel Miller

Daniel Miller is a reporter at POLITICO covering the intersection of entertainment, media, sports, technology and politics.Part of POLITICO’s California team since 2026, he examines how Hollywood and Southern California function as engines of political power. Daniel also covers the rainmakers, dealmakers and cultural figures who shape policy debates, elections and public life far beyond the state’s borders.Daniel previously spent 13 years at the Los Angeles Times, most recently as an enterprise reporter in the newspaper’s Metro department, where he worked on investigations and features. He wrote about allegations of sexual misconduct at L.A.’s Magic Castle, chronicled the cratering ventures of a celebrity vegan chef and detailed themystery of a missing million-dollar pocket watch once owned by J.P. Morgan. In 2019, he wrote, reported and hosted "Larger Than Life," an award-winning podcast about the life of an enigmatic L.A. street racer.He previously covered the business of entertainment for The Times, examining the fraught political ties between the Walt Disney Co. and the city of Anaheim, probing the world of second-tier talent agents operating on Hollywood’s fringes and uncovering allegations involving several #MeToo figures.Daniel was named Journalist of the Year at the 2015 National Arts & Entertainment Journalism Awards and, a year later, received the L.A. Press Club’s Entertainment Journalist of the Year award. He was also a finalist for the 2016 Loeb Awards for "Selling Stardom," a series on unscrupulous Hollywood operators. His narrative reporting has been honored by organizations including the Society for Features Journalism, the National Association of Black Journalists and the Motor Press Guild.Daniel began his career reporting in Southern California, writing for the Ventura County Star, the Los Angeles Business Journal and the Hollywood Reporter. He attended Beverly Hills High School and UCLA. He lives in Los Angeles.

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Feb 18 • 11:10 PM EST • Politics • politico.com
How an aging California is turning to senior centers for romance, community and health

No two senior centers are alike. We visited three very different venues in L.A. to learn how they're changing to meet the needs of California's aging population.

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Feb 18 • 8:30 AM EST • Health • calmatters.org
L.A. business owners slam city after entire block of stores flooded: ‘No one was doing anything’

A string of stores in the Fairfax District of Los Angeles were damaged by flooding during Monday’s torrential downpours, and business owners say this is a reoccurring issue that the city fails to f…

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Feb 17 • 1:04 PM EST • Business • ktla.com
Nithya Raman stunned the L.A. political world in 2020. Now, she wants to do it again

Raman's late entry will make it more difficult for her to get endorsements and raise money. She will have to work at double speed to build a campaign infrastructure and tap into bases that have helped her win before.

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Feb 17 • 6:00 AM EST • Politics • latimes.com
Man, woman shot at L.A. County business; suspect found dead with self-inflicted wound

A suspect turned a gun on himself following a shooting in Baldwin Park that left a man and woman in critical condition, police confirmed. On Monday, the Baldwin Park Police Department s…

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Feb 16 • 8:21 AM EST • Business • ktla.com
Adam Silver forced to address competitiveness, Clippers, more crises amid commissioner's most challenging year

Silver addressed the media at NBA All-Star Weekend in L.A., and there was not a shortage of burdensome topics

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Feb 14 • 8:00 PM EST • Sports • cbssports.com
7 L.A. County Public Health clinics to close after $50M funding cut

Seven Los Angeles County public health clinics will stop providing services later this month after the county lost more than $50 million in federal, state and local funding, officials announced. Th…

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Feb 13 • 2:03 PM EST • Health • ktla.com
Trump immigration sweeps upended L.A.'s economy, with some businesses losing big

The report, commissioned by L.A. County officials, found that 82% of businesses surveyed reported negative impacts from immigration enforcement, with 44% losing more than half their revenue.

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Feb 13 • 6:00 AM EST • Business • latimes.com
L.A. County officials push new sales tax to offset Trump administration healthcare cuts

L.A. County supervisors and healthcare advocates are pushing for a half-cent sales tax to cover services that are expected to be lost due to cutbacks in federal funding.

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Feb 10 • 8:14 PM EST • Health • latimes.com
LA County supervisors vote to add sales-tax hike for health care to June ballot

L.A. County voters will decide in June whether to approve a temporary half-cent sales tax in an effort to support health care services.

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Feb 10 • 7:18 PM EST • Health • abc7.com
Rihanna Makes a Chic Run to the Grocery Store in L.A., Plus Emma Stone, Kate Hudson, Gigi Hadid and More

Rihanna makes a chic run to the grocery store in L.A., Plus Emma Stone, Kate Hudson, Gigi Hadid and more. From Los Angeles to New York City, and everywhere in between, see what your favorite stars are up to.

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Feb 10 • 7:00 AM EST • Entertainment • people.com
Lakers player grades: L.A. can't crack Thunder's championship defense

On Monday, the Thunder proved why they're simply on a higher level than the Lakers.

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Feb 10 • 2:44 AM EST • Sports • lebronwire.usatoday.com
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Commentary: Wild week in the race for mayor sets up a referendum on L.A.'s political transformation

L.A. Mayor Karen Bass won't have big-name opposition, but has she earned a second term?

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Feb 7 • 3:35 PM EST • Politics • latimes.com
AI’s latest 20-something billionaire got his start at L.A. garage sales

Meet the LA boy who turned a multi-millionaire starting an AI training company

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Feb 7 • 6:00 AM EST • Business • latimes.com
L.A. Clippers reportedly sending former MVP James Harden to Cavaliers for 2-time All-Star Darius Garland, pick

The 36-year-old Harden is averaging 25.4 points per game this season.

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Feb 3 • 8:54 PM EST • Sports • sports.yahoo.com
Columbia college features new pitch competition at 7th annual B.L.A.C.K Business Expo

Columbia College, Saturday, in partnership with the James and Anelle Whitt Entrepreneurial Development Foundation, held the seventh annual B.L.A.C.K or Business

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Feb 2 • 9:06 AM EST • Business • krcgtv.com
How to watch the Grammy Awards and what to know before the show starts

Before music's biggest night commences with performances from Justin Bieber and Lady Gaga, most of the Grammy Awards will be given out on Sunday afternoon in L.A. Follow along for our live updates throughout the day.

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Feb 1 • 11:00 AM EST • Entertainment • latimes.com
Bill Maher Says Hollywood Hurting Democratic Party: “Just Shut the F*** Up”

The HBO host and comic is blaming the "woke" entertainment industry for election losses and chiming in on the local state of play in California and L.A.

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Jan 30 • 2:59 PM EST • Politics • hollywoodreporter.com
CA groups seek local taxes to offset federal health care cuts

An L.A. health care coalition is trying to qualify a measure for the June ballot in order to head off impending health care funding problems.

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Jan 30 • 9:00 AM EST • Health • calmatters.org
PaleyFest L.A. 2026 to reunite 'Charlie's Angels' actors for 50th anniversary

The 2026 PaleyFest lineup includes a 50th anniversary celebration of the groundbreaking series 'Charlie's Angels,' along with panels on hit shows like 'The Pitt' and 'Pluribus.'

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Jan 26 • 10:30 AM EST • Entertainment • latimes.com
Rams-Seahawks final score: Seattle ends L.A. terrific season

The Seattle Sehawks are going to the Super Bowl, and the Los Angeles Rams are going home.

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Jan 25 • 9:53 PM EST • Sports • turfshowtimes.com
Letters to the Editor: Yes, political extremists are dangerous, but more so when they’re in power

'Wingnuts are dangerous, but mainstream wingnuts even more so. It’s time we all wake up to the reality that there is nothing conservative about MAGA populism,' writes an L.A. Times reader.

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Jan 25 • 10:00 AM EST • Politics • latimes.com
Kaiser nurses plan to go on strike statewide; several hospitals in L.A. and Orange counties to be affected

More than 31,000 healthcare professionals plan to walk off the job on Monday.

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Jan 25 • 8:00 AM EST • Health • latimes.com
Super Bowl odds: Seahawks and Rams the favorites as playoffs down to final four

Seattle and L.A. remain at the top, but New England isn't far behind. Here's a look at the latest Super Bowl odds entering the 2025 NFL season's Championship Round

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Jan 19 • 2:27 PM EST • Sports • cbssports.com
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L.A.'s defense industry is booming. Federal funding crunch could change that

A dispute over reforms to an SBA program that funds startups has cut the flow of seed money to Southern California's defense tech firms.

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Jan 19 • 6:00 AM EST • Business • latimes.com
Today’s Papers – Farewell to Commisso, Inter run away, Juventus’ blow

La Gazzetta dello SportFarewell to Rocco CommissoViola heartFiorentina lose their president: ‘We’ll play for him.’ From Calabria to the USA, from TV to football.Antognoni: ‘He gave us a lot, i...

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Jan 18 • 3:50 AM EST • Sports • sports.yahoo.com
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Letters to the Editor: Some people will always find a way to downplay the importance of science

'Periodically, I’ve had chats with neighbors about the heat. Most of the talks have been thoughtful, but some have veered into cuckoo territory,' writes an L.A. Times reader.

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Jan 16 • 11:00 AM EST • Science • latimes.com
Gap Names Former Paramount Exec Pam Kaufman Entertainment Chief Amid “Fashiontainment” Push

The retailer will also open an L.A. office: "Fashion is entertainment, and today’s customers aren’t just buying apparel, they’re buying into brands that tell compelling stories and drive cultural conversations."

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Jan 15 • 9:15 AM EST • Entertainment • hollywoodreporter.com
GOP Cuts Will Cripple Medicaid Enrollment, Warns CEO of Largest Public Health Plan

Martha Santana-Chin, a daughter of Mexican immigrants, last year took the helm of L.A. Care, the nation’s largest publicly operated health plan. She warns that looming federal cuts will push up to 650,000 people off L.A. Care’s Medicaid rolls by the end of 2028.

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Jan 15 • 5:00 AM EST • Health • kffhealthnews.org
Recent $11 Million Grant to Broad Metro Highlights Economic Partnerships Between Business and State, Federal Government - Alabama Department of Labor

FOR IMMEDIATE RELEASE January 12, 2026 Recent $11 Million Grant to Broad Metro Highlights Economic Partnerships Between Business and State, Federal Government Hoover, Alabama – A recent grant in the amount of $11,751,607.34 in federal Abandoned Mine Land Economic Revitalization (AMLER) Program funding that was awarded for two innovative projects in Hoover, Alabama—Broad […]

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Jan 12 • 5:09 PM EST • Business • adol.alabama.gov
Crossroads students begin push to make pickleball a varsity sport

Their vision has birthed the L.A. High School Pickleball League, the first of its kind in California. It's the beginning of something that could be a sanctioned sport.

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Jan 11 • 1:00 PM EST • Sports • latimes.com
Dr. Oz touts federal crackdown on healthcare fraud by 'foreign influences' in L.A.

Trump officials announced a sprawling probe into benefits fraud across California on Friday, citing what they called a massive, coordinated effort to fleece government healthcare programs.

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Jan 9 • 10:00 PM EST • Health • latimes.com
Chargers vs. Patriots prediction, odds, where to watch, live stream, kickoff time

Let's preview Sunday night's Wild Card matchup between L.A. and New England

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Jan 9 • 9:55 AM EST • Sports • cbssports.com
'If we open, we have to start over from scratch.' Businesses still stuck a year after the L.A. fires

One year after the fires, some businesses are rebuilding while others have given up.

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Jan 9 • 6:00 AM EST • Business • yahoo.com
‘If we open, we have to start over from scratch.’ Businesses still stuck a year after the L.A. fires

One year after the fires, some businesses are rebuilding while others have given up.

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Jan 9 • 6:00 AM EST • Business • latimes.com