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Dustin Poirier: Zuffa Boxing not an option for UFC fighters
In recent years. several former or retired UFC fighters have extended their combat sports careers by transitioning to boxing. Former champions Tyron Woodley, Anderson Silva and Francis Ngannou have. Ben Askren, Nate Diaz, Jorge Masvial, Mike Perry and Darren Till also have, among others. Former ...
In new memoir, Bottoms says hardships shaped her political identity
The Democratic contender for governor writes about private trauma and public slights, arguing those hardships forged the leader now asking Georgians for a promotion.
Newsom PAC bought thousands of memoir copies about his hardships, juicing sales
Campaign finance filings reveal Gavin Newsom's PAC bought 67,000 copies of his memoir for over $1.5 million amid his 2024 presidential positioning.
Finish Line: The quiet rise of "prescribing connection"
Physicians are sending patients to choirs, art studios, walking clubs and lakesides.
Lena Dunham on New Memoir, Jack Antonoff, Health Issues, More
Writer, director, and actor Lena Dunham joins TODAY’s Jenna Bush Hager and Sheinelle Jones to talk about her new memoir, “Famesick: A Memoir,” where she opens up about her health, experience with fame, and what it means to come of age under the intense scrutiny of Hollywood. Dunham talks about the negative attention she got while starring in “Girls” and how it exacerbated her health issues, reflects on her breakup with Jack Antonoff, and opens up about her battle with pharmaceutical dependency. Dunham also shares the story of how she came to the decision to get a hysterectomy when her endometriosis became unbearable, despite her dreams of being a mother.
Virginia Health Officials Issue Fish Consumption Advisory for John W. Flannagan Reservoir
April 15, 2026 Media Contact: Brookie Crawford, brookie.crawford@vdh.virginia.gov Virginia Health Officials Issue Fish Consumption Advisory for John W. Flannagan Reservoir Contaminants Identified in Walleye, Channel Catfish, Largemouth Bass RICHMOND, Va. – Effective immediately, the Virginia Department of Health (VDH) is issuing a fish consumption advisory for the Flannagan Reservoir due to elevated polychlorinated biphenyls (PCBs) […]
In Charlotte, Kamala Harris calls out Trump’s ‘obviously wrong’ Pope Leo post
The former vice president and presidential candidate was back in Charlotte Tuesday night promoting her campaign memoir.
Cleveland Browns NFL Draft Profile: CB Mansoor Delane, LSU
The Browns could use another cornerback. But is a first-round pick too high a price to pay this year?
Seniors: Carol Watson, 72
Owner of Carol Watson Greenhouse and Landscaping in LaFayette enjoys her growing business — still puts in six-, seven-day weeks By Mary Beth Roach Carol Watson, the owner of Carol Watson Greenhouse and Landscaping, has been in gardens since she could walk. Literally. She said she learned to walk in her grandfather’s garden, which was next door to her current home and business in LaFayette. Today, at 72, she is running the business that her mother, Claire, opened in 1981 as Watson Greenhouse. Watson worked part-time for her mom until 1990, when she joined her full time. While she may not have had any formal horticultural experience, she said she learned so much about growing and raising plants from her mom, who had an abundance of energy and talent. Now, after 35 years in the business full time, Watson has no plans to retire, although she joked that she’d like a couple of days off a week. On her seven-acre site, complete with four greenhouses, Watson said her favorite parts of the job are working with and educating her customers; helping some of her young customers build terrariums; conducting occasional class field trips; and supporting local art by decorating the shop with an eclectic mix of pottery from at least four area craftspeople. A one-time employee of the former Dey Bros. department store in Syracuse, Watson said she loves merchandising and enjoys displaying unique pieces of art on shelves and even suspending from ceilings. “We’re creative. We also had top quality plants. We got a reputation of quality plants and unusual products,” she said. It’s tending to her customers and her plants, showcasing the unusual products, and hosting special events to benefit the community that keep her motivated to work six to seven days a week. “I just love it. I love taking care of the plants. I’m one of the few people that really enjoys watering,” she said. And while she has cultivated a solid customer base over the years, she remains savvy in her marketing efforts to draw in new customers. For example, she does a gardening segment on CNY Central television; her active Facebook page has thousands of followers; and she hosts a number of unique events and classes that not only introduce her shop to potential new clients, but some benefit nonprofits as well. About 13 years ago, when the local symphony orchestra was struggling, she said she wanted to help. So, partnering with the group, she began offering concerts, called Soirees, featuring the Syracuse Orchestra’s string quartet. Following up on a suggestion from a customer whose brother is a deejay in retirement, specializing in sock hops, she hosted the greenhouse’s first sock hop. Plants got moved back toward the walls to make room for dancing; a caterer was brought in, offering diner-like food; guests came in period outfits; and proceeds went to the Food Bank of CNY. She is excited about doing it again in October. Via her website, she promotes the greenhouse as an “oasis in the snow,” offering visitors the opportunity to pick up some decorating and gift ideas while taking in the floral and citrus scents. And she also caters to her four-legged friends. Over this past winter, she said, she came up with a “brilliant idea,” although at the time she didn’t appreciate just how brilliant it would become. Feeling it too cold outside to take her dog for a walk, she opted to bring it into the greenhouse. And before long, she was inviting people to bring their dogs into the big greenhouse as well. She looks forward to extending that invitation again this upcoming winter season. For Watson and her customers, the greenhouse is always in season.
French government says au revoir Windows, bienvenue Linux
It's part of a broader European movement to reduce reliance on American tech.
49ers land Steelers’ 16-sack edge rusher in trade proposal
The 49ers could use their draft capital to upgrade positions of need with veterans instead of rookies.
Colin Kaepernick to publish memoir 'The Perilous Fight' in September
s e police-brutality political-and-civil-unrest protests-and-demonstrations sports nfl-football football entertainment | Newsradio 1140 WRVA
Small Business Expo coming to Bladen County this month
The event brings together entrepreneurs, startups and businesses to network, collaborate and grow.
Colin Kaepernick to publish memoir 'The Perilous Fight' in September
Colin Kaepernick will publish his life story, “The Perilous Fight,” on Sept. 15. The former San Francisco 49ers quarterback and activist completed the memoir almost 10 years after he first
Former NJ Gov. Chris Christie on Leadership and the Political Landscape
Former New Jersey Gov. Chris Christie (R) discusses leadership, the upcoming midterm elections, and the political landscape during a conversation hosted by the Institute of Politics at Harvard Kennedy School.
Country music star and husband planning to have kids: ‘Little ones say that it is OK’
The singer has been opening up about his life around he release of his new memoir.
Can You Name That Political Memoir? A Slate Quiz.
We’re in prime politicians-releasing-platitude-filled-books season. But do you know how platitude-filled?
‘The Drama’ review: Fine performances can’t save uninteresting story
"The Drama," starring Zendaya and Robert Pattinson, fails to answers its central questions, writes Moira Macdonald.
Landsat Reveals Reservoir Changes and Bathymetry
In two recent studies, researchers used Landsat data to fill key gaps in our knowledge of reservoir structure and dynamics.
Scientists discover potentially huge freshwater reservoir hidden beneath Great Salt Lake
Researchers have found a layer of fresh water beneath Utah's Great Salt Lake that reaches up to 2.5 miles deep and could turn out to be as big, or bigger, than the lake.
MICC Fort Belvoir employees recognized for support to the Army Warfighter Brain Health Task Force
FORT BELVOIR, VA- Three employees from the Mission and Installation Contracting Command, Fort Belvoir office were recently recognized by the Office of t...
2 Seattle authors shine in April’s best paperback releases
From Moira Macdonald's debut novel to the first book in a cozy sci-fi mystery series from Olivia Waite, there's plenty of new paperbacks to add to your TBR list.
Thieves steal paintings by Renoir, Cézanne and Matisse from Italian private museum
i e theft crime painting entertainment world-news general-news | KCBS All News 106.9FM and 740AM
Scientists Just Found a Massive Freshwater Reservoir Hidden Beneath the Great Salt Lake
The drying out of the Great Salt Lake has been a growing problem, but the surprising arrival of reed-filled mounds inspired scientists to investigate what lies beneath.
Celebrate business owners and community with Seattle Women's Network's April 4 soiree
One of Earth’s most explosive supervolcanoes is recharging
Far beneath the ocean near Japan, scientists have discovered that the magma system linked to the most powerful eruption of the Holocene is slowly rebuilding. By using seismic imaging, researchers mapped a large magma reservoir under the Kikai caldera and confirmed it is the same system that fueled the massive eruption 7,300 years ago. However, the magma now present is newly injected, not leftover, as shown by changes in the chemistry of recent volcanic material and the growth of a lava dome over thousands of years.
Scientists discover why cancer drugs don’t work for everyone
Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release reservoirs that create uneven drug distribution. This means some cancer cells are heavily exposed while others are barely affected. Understanding this process could help doctors better tailor treatments and improve outcomes.
The Shocking Speed of China’s Scientific Rise
When will Chinese research pull ahead of ours?
Singing in Britain's Got Talent choir 'helps mental health' says farmer
Ben Brooke is part of a choir of farmers which has wowed viewers of Britain's Got Talent.
We disagreed on politics. We agreed on wine. That was enough.
At the Virginia Governor’s Cup Gala in Richmond earlier this month, a very dapper gentleman approached me and introduced himself. In his light-colored suit and bowtie, he looked very Southern in a classical sense, the sort of Virginia Gentleman you used to see south of the Rappahannock as recently as my college days. “I’m a longtime reader and fan of your writing, if not your politics,” he said. His comment was the proverbial iron fist in a velvet glove, simultaneously conveying praise and disapproval while establishing boundaries. Man, I wish we still discoursed like this instead of shouting bromides and insults to try and “own” our opponents with a funny meme and a furrowed brow. Subscribe “Well, we’ll always have wine to share together,” I said, and thanked him for his kind words. We clinked glasses, exchanged pleasantries about the delicious gold medal-winning wines being poured that evening, and went our separate ways. Our exchange reminded me that more unites us than divides us. Wine brings people together to share a meal and a few hours of joy despite our differences.1 That’s why I refer to the wine community — including readers and consumers — rather than the wine industry. Together, we are so much more than production, distribution and sales statistics. A few minutes later the evening’s awards ceremony began. Applause grew as the 12 winemakers who made the top-scoring wines for the Governor’s Case took the stage, including a loud cheer for Jonathan Wheeler of Trump Winery and his 2018 Blanc de Noir sparkling wine. All the winemakers on stage had reason to be proud, Wheeler perhaps more so. Trump Winery was the only winery to win six gold medals in the competition this year. (Wineries are limited to six entries.) Two of Wheeler’s ciders also won gold medals in a separate competition. When you cover the labels and take the sour taste of politics off your palate, the wines are pretty darn good.2 Then Gov. Abigail Spanberger, newly elected Democrat and Virginia’s first female governor, was introduced to great applause to announce which of the 12 wines had won the Governor’s Cup. She spoke for a few minutes about the importance of wine to Virginia’s economy and tourism and the international acclaim Virginia wine has received. Just two weeks earlier, she gave the Democrats’ response to Trump’s State of the Union speech, but this night wasn’t about politics. That didn’t stop several people in the crowd from speculating on the irony should she have to present the trophy to Trump Winery. In the end, Valley Road Vineyards was displayed on the screen behind Spanberger as the winning winery. Blue Bee Cidery in Richmond took top honors for that category. The crowd cheered a female governor presenting the state’s highest trophy to a female winemaker and then resumed the evening’s festivities, united by their mutual love of wine. A whiff of politics couldn’t dim the cheer of celebration and a community united by its love of wine. In Memoriam: Michel Rolland The global wine community lost a giant March 20, with the passing of Michel Rolland. He was 78. Rolland was the original “flying winemaker,” a globe-trotting consultant who helped Bordeaux regain its mojo in the 1970s and then shaped the rise of Napa Valley cult Cabernet as consultant to Simi, Harlan, Newton, Screaming Eagle, Araujo, Dalle Valle and other wineries. He was instrumental in Argentina’s rise to prominence and even had his own winery, Clos de los Siete, in a partnership with other wine families. Rolland’s career arc paralleled that of Robert Parker, the world’s most influential critic. Parker championed many of the wines Rolland consulted on, helping build his reputation and demand for his services. It also made him a target for Parker’s critics. As W. Blake Gray wrote on Wine-Searcher in his excellent tribute to Rolland: Rolland created the type of wines Parker loved: rich body, plenty of fruit, soft tannins. He sometimes faced the accusation of creating a generic international style of red wine, where the great wines he made in Argentina were indistinguishable from the great wines he made in France. Rolland chafed at that critique, as did many of his fans. He was credited with championing green harvesting and leaf pulling, as well as careful selection of grapes in the winery, practices we nearly universally think of today for high-quality winemaking. “Michel was an incredible innovator who changed how wine was made and how grapes were grown,” Napa Valley winemaker Aaron Pott wrote on Facebook. “His work has transformed the wine trade. He created new ways of looking at wine, tasting wine, evaluating ripeness and quality. … This was not just a man with a ‘style’ that he imposed on vineyards but a man that understood how to make great wine from great sites.” Rolland started his consulting company in 1973 in Libourne, in Bordeaux, with his wife, Dany. Both had graduated the year before from Bordeaux’s Institute d’Oenologie. The couple sold their majority share in the business in 2020, according to Wine Spectator. Over his career, Rolland reportedly worked with more than 100 wineries in 20 countries. He even made it to Virginia, where he consulted for Kluge Estate in the mid-2000s. (Kluge Estate is now Trump Winery.) Reader feedback, please! Last week, I did my first WineLine Live! with Dr. Laura Catena of Catena Zapata winery in Argentina. We enjoyed a fascinating discussion about her efforts to preserve the genetic heritage of old vineyards in Mendoza. I conceived of WineLine Live! for paid subscribers, as a thank you for your financial support. And while only a few people joined live, the video now has more views than I have paid subscribers, so I guess that’s pretty good. Even so, I’m considering opening future installments to anyone on Substack to reach a broader audience. So my questions to you: Should these be public? And what format do you prefer? Live gives a chat feature with the potential for viewers to interact with me and the guest, while a video post would just be that. Another alternative is a podcast, which would just be audio, without video of my chins. Please let me know in the comments. Leave a comment In the Glass A few wines I’ve enjoyed recently: Bonny Doon Vineyard Take Me to Your Liter, Le Cigare Volant, Red Wine of the Earth. 2023, Central Coast, CA. Blend of Grenache, Syrah Cinsaut and Petite Sirah. Delightful wine with expressive red fruit flavors, casual drinking. Doon lovers of a certain age will remember Randall Grahm’s Big House Red; this is more in that style than his original Le Cigare Volant, modeled after Chateauneuf du Pape. The liter bottle makes it an even better value. I see this online at about $15. Great value. Albert Bichot Bourgogne Pinot Noir Origines 2023. 13% - Textbook pinot noir and an excellent, affordable entry (regional) Burgundy. Wine Enthusiast Top 100 Wines of 2025. $24 at Total Wine & More. Loma Larga Pinot Noir 2021 “Coastal Cool Climate Wine”, Valle de Casablanca, Chile. An older sample, showing beautifully. Spicy and fruit forward. I’m seeing widely varied pricing online, from $18-$32. At the lower end, it’s a terrific value. 13.5% Dr. Loosen Riesling Dry 2016, Mosel, Germany. Found this “in the stack.” And it stacked up well, shedding some of its youthful acidity for opulent Riesling character, including a hint of the mineral oil older Riesling often features. A great value, as I’m seeing it as low as $14 online. 12% abv. Red Tail Ridge Blau Franc Blend 2024, Sans Oak, Finger Lakes. 13.4% abv. The name is a neat portmanteau of Blaufrankisch and Cabernet Franc, thus Blau Franc. The blend is 50-50, no oak involved. The Blau dominates on the palate, with the spicy caraway seed (think New York deli rye bread). The Franc adds body. The result is juicy, energetic and joyful. Sokol Blosser Estate Rosé of Pinot Noir 2025, Dundee Hills, Willamette Valley, Oregon. This first rosé of 2025 was a welcome respite to our cold, snowy winter here in the Mid-Atlantic. Oh man, I needed this! Bright and energetic, exuberant even, it perks up the mood and goes down fast. 13%. Certified B Corp. Ingredient and nutrition labeling, and in a modest way that doesn’t occupy a lot of label space. (Since it’s not required, presumably there are no minimum font size requirements.) More wineries should follow this example. Dave McIntyre's WineLine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe Thanks for reading Dave McIntyre's WineLine! This post is public so feel free to share it. Share 1 Some restraint may be required. 2 Especially the bubblies.
US soccer legend Landon Donovan details mental health struggles in new book
American soccer great Landon Donovan talks to Fox News Digital about the themes in his new book, "Landon: A Memoir."
Emmanuel Grégoire, Socialist long involved in local politics, voted new Paris mayor; AP explains
Grégoire won over 50% of the votes, beating out prominent conservative contender Rachida Dati who reached 41% while hard-left contender Sophia Chikirou got about 8%.
Lenoir-Rhyne Sports Hall of Fame Nominations Due April 1
HICKORY, N.C. - Nominations for the Lenoir-Rhyne Sports Hall of Fame are due by Wednesday, April 1. The 2026 Hall of Fame ceremony will take place on Saturday, September 19, prior to Lenoir-Rhyne's 6:00 p.m. football game vs. Mars Hill.
Emmanuel Grégoire, a Socialist long involved in local politics, becomes Paris' new mayor
Emmanuel Grégoire has won the Paris mayoral race and takes over from fellow Socialist Anne Hidalgo
Socialist Emmanuel Grégoire elected Paris mayor in runoff vote
Emmanuel Grégoire has won the Paris mayoral race and takes over from fellow Socialist Anne Hidalgo. On Sunday, he sealed the moment by riding a city bike to City Hall.
US soccer legend Landon Donovan opens up on mental health struggles, redefining success
American soccer legend Landon Donovan opened up about mental health struggles and reconfiguring what success meant to him. He releases "Landon: A Memoir" this week.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
A massive freshwater reservoir is hiding under the Great Salt Lake
A hidden freshwater system deep beneath the Great Salt Lake has been revealed using airborne electromagnetic surveys. Scientists found that freshwater extends much farther under the lake than expected, reaching depths of up to 4 kilometers. The discovery began with mysterious reed-covered mounds formed by pressurized groundwater pushing upward. Researchers are now investigating whether this underground water could help control hazardous dust from the drying lakebed.
Good Sports: El Capitan High School baseball players commit to college together
Cooper Gaoiran and Zach Hunter have always been a package deal. That's been the case for as long as they remember, all the way back to t-ball.
How a Madison maestro composed his life, career in American music
John DeMain will soon retire from the Madison Symphony Orchestra and Madison Opera. In a Cap Times interview, he talks about his career and his published memoirs.
Trey Hendrickson agrees to 4-year, $112 million contract with Ravens following failed Maxx Crosby trade
PWHL to reach national U.S. TV audience with Scripps Sports to broadcast neutral site game in Detroit
The Professional Women’s Hockey League is coming to a TV set near you in the United States. The league announced its neutral-site game at Detroit on March 28 between the New York Sirens and Montreal Victoire will be the first accessible to a national U.S. television audience.
Jill Biden's new memoir will offer her perspective on the decision to end Biden's 2024 reelection bid
A political spouse for nearly 50 years, Jill Biden said she has never publicly discussed her feelings about the three-week stretch when her husband ended his political career, instead saving her thoughts for the pages of her soon-to-be-released memoir.
Liza Minnelli says late costar Gene Hackman was 'downright rude' on set of 'Lucky Lady'
Liza Minnelli writes in her new memoir that the late Gene Hackman was 'downright rude' to her on the set of the 1975 comedy-drama 'Lucky Lady.'
In new memoir, Gov. Gavin Newsom reflects on his political rise
As California’s governor – and a topic of discussion among some as a possible 2028 presidential candidate – Gavin Newsom is an exceedingly public figure with a busy schedule to match. His new memoir, Young Man in a Hurry, provides a glimpse into Newsom’s rise to political prominence and his ongoing goal of self-discovery. In today’s episode, Newsom sits down with NPR’s Ailsa Chang to discuss his book, the question of his own relatability, and why he uses “playground insults”’ on social media to push back against the Trump administration.To listen to Book of the Day sponsor-free and support NPR's book coverage, sign up for Book of the Day+ at plus.npr.org/bookoftheday
How Taiwan Is Reclaiming Its Wine Identity—Through Climate-Adaptive Science and Terroir-Driven Fermentation
Christina Applegate knew her marriage to Johnathon Schaech was doomed at the wedding: 'This man was not for me'
In her new memoirm 'You With the Sad Eyes,' Christina Applegate looks back on her first marriage to Johnathon Schaech: 'If you go on a first date with a guy and you don't like his shoes, run.'
Christina Applegate recalls losing her virginity at 16 while playing promiscuous teen on 'Married With Children'
Former child star Christina Applegate reflects on her tumultuous rise to stardom in her new memoir and shares how vastly different her real-life experiences were from her onscreen life.
MAGA Calling Newsom Racist? That’s Rich
Gavin Newsom has been reveling in the attention that comes with being the early frontrunner for the 2028 Democratic presidential nomination. But the California governor also seems to understand that he has work to do to convince voters that he’s more than just a slick-talking, coastal elite with progressive politics and a pretty face. To that end, he spent much of last week in the South promoting his new memoir, “Young Man in a Hurry.”
Kamala Harris praises small businesses, condemns Iran bombing while in Detroit
Harris was in Detroit this weekend to promote her new memoir, \
Assessing Kenyon Sadiq's performance at the 2026 NFL Combine
With Kenyon Sadiq performing at the NFL Combine on Friday, let's take a look at how he stacked up against the rest of the field.
Scientists confirm a mysterious “cosmic barcode” hidden near black holes - Futura-Sciences
It is hard to believe, but it has already been ten years since the first detection of a gravitational wave source. Named GW150914, after the date of its observation on 14 September 2015, the signal reached Earth and opened an entirely new chapter in astronomy. It marked the first direct...
Small Business Admin. IG Testifies on Fraud in Small Business Relief Programs
Small Business Administration Inspector General William Kirk and Pandemic Response Accountability Committee Executive Director Kenneth Dieffenbach testify on fraud in small business relief programs before the Senate Small Business Committee.
Among the gangsters, gamblers and high rollers: a master bookie’s life in Las Vegas
In his new memoir, Art Manteris recalls raucous times in Nevada, and explains why the explosion of sports betting in the US presents serious risks
NSF–DOE Vera C. Rubin Observatory Launches Real-Time Discovery Machine for Monitoring the Night Sky
NSF–DOE Rubin Observatory has issued its first scientific alerts, marking a historic milestone in astrophysics. Expected to increase to seven million alerts per night, these first alerts start a new era of dynamic, real-time observation of the night sky.
Essay: Gavin Newsom: They told me it was political suicide. I did it anyway
In an exclusive excerpt from his new memoir, Governor Gavin Newsom recalls how George W. Bush’s 2004 State of the Union inadvertently sparked a revolution in California civil rights.
Water agencies voice continued concerns about health of Stagecoach Reservoir
Upper Yampa Water Conservancy District, which owns and operates Stagecoach Reservoir, continues to address two major issues regarding the reservoir’s future related to the proposed 6,100-acre Stagecoach Mountain Ranch development — water supply and water...
Five Berkeley Lab Scientists Receive DOE Early Career Research Awards
Five scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) have received Early Career Research Program (ECRP) awards from the Department of Energy. The ECRP program, now in its 16th year, was established to bolster the nation’s scientific workforce by supporting exceptional researchers at the outset of their careers, when many scientists do their most formative work. Recipients use the funding to pursue projects that have the potential to solve scientific challenges and advance the country’s STEM capabilities. To be eligible for the program, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution, or a full-time employee at a DOE national laboratory or Office of Science user facility, who is within 10 years of having earned their doctorate. Awards to an institution of higher education will be approximately $875,000 over five years, and awards to a DOE national laboratory or Office of Science user facility will be approximately $2,750,000 over five years. This year’s Berkeley Lab awardees and their projects are listed below: Timon Heim: Better detectors for more powerful particle colliders Timon Heim is a staff scientist in the Physics Division. His ECRP project will develop a new type of detector that can track the particles generated by collisions in particle colliders with high spatial and temporal resolution. Current detectors in use at high-energy colliders, like the ATLAS detector at the Large Hadron Collider (LHC) at CERN, can track the trajectory and measure momentum of particles, but they can’t track a particle’s time of arrival with sufficient precision to discern from which of the many particle interactions they originate. Heim’s proposed technology — called a 4D tracking detector, because it captures data about particles’ positions in space and time — aims to solve this challenge, allowing researchers to glean more precise data from collision experiments to uncover new insights into fundamental forces and potentially discover new particles. The enhanced capabilities of 4D detectors will be a necessity for experiments at future colliders, such as the Muon Collider or Future Circular Collider. The project will develop custom microelectronics that process the signal of a pixelated silicon sensor that can register charged particles passing through it in an extreme radiation environment that these colliders produce during operation. The goal is to measure individual particles’ position with 50-micro-meter spatial and 50 pico-second (one trillionth of a second) temporal precision, for an incoming flux of around 1 billion particles per second per square centimeter. Harrison Lisabeth: Studying underground processes to unleash abundant energy Harrison Lisabeth is a research scientist in the Energy Geoscience Division focused on combining real-world experiments and AI to guide development of geothermal energy systems. His project will explore how deep underground rock formations – where geothermal wells are dug – are stressed by chemical reactions of the minerals and mechanical strain from movements in the Earth. A better understanding of subsurface stresses is essential to engineer safe and reliable geothermal wells that access the heat of deep rocks to produce electricity. It is estimated that the U.S. could generate ten times the amount of energy needed to power the grid using geothermal sources. Lisabeth plans to simulate how minerals grow, dissolve, and influence the behavior of surrounding rock in geothermal reservoirs by tracking chemical changes in rock samples under pressure in the lab. The project will also develop machine learning models to predict geologic strain based on field measurements and refine existing models that describe how common rock types deform under stress. Combining these approaches, Lisabeth hopes to develop a framework to predict stress to improve stability and longevity of geothermal wells. Daniel Carney: Pushing the quantum boundaries of particle measurement Daniel Carney is a staff scientist in the Physics Division who uses quantum information science to study particle physics and gravity. At very small scales, “quantum noise” — random fluctuations from the act of measurement — can drown out faint signals from rare processes. Carney’s ECRP project, “Fundamental Physics at the Quantum Limits of Measurement,” aims to build a new mechanical quantum sensor that can measure extremely small particle interactions below the limits of that quantum noise. The approach uses lasers to hold a tiny bead containing radioactive atoms; when one decays, the system measures the bead’s motion and the energy of any particles emitted. The experiment’s initial goal is to search for heavy sterile neutrinos, hypothetical particles predicted by some extensions of the Standard Model. The system could also help measure the mass of the neutrino, study the way particles interact through the electromagnetic and weak forces, and hunt for low-mass dark matter — all unsolved mysteries in particle physics. Callum Wilkinson: Using machine learning to demystify neutrinos Callum Wilkinson is a staff scientist in the Physics Division and part of the international Deep Underground Neutrino Experiment (DUNE) hosted by Fermi National Accelerator Laboratory. DUNE will create an intense beam of neutrinos that interact in detectors in Illinois and, after an 800-mile journey through the earth, in massive detectors in South Dakota. By precisely measuring neutrinos and how they change, researchers will get a better understanding of their fundamental properties and whether they are responsible for why there is so much more matter than antimatter in our universe. Wilkinson’s ECRP project will apply two machine learning techniques to improve the analysis of DUNE’s data and enhance the experiment’s precision. One approach will look for hidden patterns in how neutrinos interact and produce low-energy particles, while the other will help correct for distortions in what the detectors record. The methods will be tested on one of DUNE’s prototype detectors and could be used in other neutrino experiments, improving their measurements and helping scientists build better models. Aditi Krishnapriyan: Machine learning methods that scale as datasets grow Aditi Krishnapriyan is a faculty scientist in Berkeley Lab’s Applied Mathematics and Computational Research Division (AMCR) and assistant professor at UC Berkeley. Her project, awarded through UC Berkeley, will develop machine learning methods that scale with dataset size for modeling complex, multi-scale phenomena. The resulting tools can be applied in a wide range of research, including the study of new electrolytes for batteries or the examination of molecular interactions. ### Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science. DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.
NASA Captures an Extremely Rare Atmospheric Phenomenon Above the Pacific - Futura-Sciences
However, these aren’t actually rainbows but a phenomenon known as “glory.” It’s an optical event often spotted from airplanes, caused by the refraction of sunlight on the water droplets that make up the clouds. In reality, there is a single glory, stretching about 480 kilometers, consisting of two multicolored edges....
A Cosmic “Barcode” Has Indeed Been Detected Around Black Holes - Futura-Sciences
It is hard to believe, but it has already been ten years since the first gravitational wave source was discovered. Named GW150914, for gravitational wave and the date of its observation, September 14, 2015, the signal reached Earth on that day and opened a new era in astronomy. GW150914 marked...
The two separate lives of Gavin Newsom detailed in new memoir
In his new memoir "Young Man in a Hurry," Gov. Gavin Newsom writes about the occasional interludes into his father's life charmed by the Getty oil family's affluence and the everyday struggle living with his single mom.
‘Wuthering Heights’ review: A messy, occasionally irresistible adaptation
Emerald Fennell's "Wuthering Heights," starring Margot Robbie and Jacob Elordi, is basically fan fiction of Emily Brontë’s 1847 novel, writes Moira Macdonald.
Covenant Health acquires urgent care in Lenoir City, Knoxville
KNOXVILLE, Tenn. (WATE) — An urgent care with locations in Lenoir City and Knoxville has been acquired by Covenant Health in a move that leaders say will expand access to the community. Lakeway Urg…
'Overwatch' just hit its highest player base on Steam PC since launch — passing Battlefield 6 and Call of Duty
All it needed was a flying kitty. Overwatch is so back, as the kids say.
Remembering Catherine O’Hara and her iconic ‘Schitt’s Creek’ character
The actor died at the end of January at the age of 71. Moira Macdonald pays tribute to her and her unforgettable persona as Moira Rose on "Schitt's Creek."
Record-Breaking One-Off Bugatti Brouillard Could Become the Most Expensive Bugatti Ever
A one-off aimed at a historic record Bugatti’s latest one-off, the Brouillard, steps onto the hypercar stage with the quiet confidence of a record-breaker. The brand’s tradition of bespoke excellence meets a bold new aesthetic, positioning this unique commission to potentially become the marque’s most expensive creation. Built on the proven underpinnings of the Chiron/Mistral architecture, yet transformed by distinctive craft, the Brouillard is both homage and innovation. A name born from equestrian legend More than a century ago, a striking white horse captivated Ettore Bugatti in Molsheim. That equine myth now informs the car’s name and its sensory identity. The result is an automotive portrait of athletic grace—surfaces that read like muscle, curves that suggest motion, and details that quietly speak of discipline and heritage. Embroidered horse motifs on door panels and seat backs echo the story, while a miniature glass sculpture of the steed crowns the shifter. Sculptural design with purpose The Brouillard’s silhouette favors sinuous surfaces over hard creases, allowing light to glide over its form like a tendon under skin. Aerodynamics inform elegance: an integrated ducktail replaces a deployable wing, cleansing the airflow and boosting stability at speed. Its stance is athletic, its volumes taut, and its visual language unmistakably Bugatti. “Sculptural, organic forms—like a tendon beneath the skin—hide immense power behind noble simplicity,” said design chief Frank Heyl, capturing the car’s philosophy in a single stroke. Craft elevated to an art The cabin embraces craftsmanship at an uncommon level. Custom-woven textiles from Paris introduce a discreet tartan pattern, while green-tinted carbon fiber nods to the exterior’s hue. A glazed roof creates a cathedral atmosphere, bathing the cockpit in natural light. A central spine appears to flow from exterior to interior, emphasizing continuity and structure. Highlights include: Custom textiles with subtle tartan motifs Green-tinted carbon fiber matched to the exterior finish A “cathedral” glass roof that elevates cabin ambience A sculptural centerline linking outside to inside Bespoke embroidery and glass equine detail W16 power at its absolute apex Under the sculpted skin, the final evolution of Bugatti’s 8.0‑liter, quad‑turbo W16 delivers a thunderous 1,600 hp at 7,050 rpm and 1,600 Nm of torque. This represents the pinnacle of nearly two decades of Bugatti engineering, honed to an ultimate state. The lightweight monocoque blends carbon fiber with aluminum, holding mass to around 1,900 kg for poise and control. Experts suggest the Brouillard could surpass the 282 mph (454 km/h) achieved by the Mistral, aided by more aerodynamic bodywork and the fixed ducktail. Whether or not it sets a new benchmark, its intent is clear: relentless speed paired with refinement. Exclusivity with an exacting timeline The commissioning process is intensive, with roughly 18 months of development leading to a 2027 delivery. Bugatti’s program limits itself to no more than two creations per year, ensuring focus and rarity. Each example leaves the atelier as a singular vision, shaped to the client’s collection and the brand’s ethos. An unveiling is planned for Monterey Car Week 2025, placing the Brouillard amid the world’s most discerning enthusiasts. Its patron is a European collector deeply invested in the Bugatti universe, from historic and modern cars to Carlo Bugatti furniture and Rembrandt Bugatti bronzes. A valuation poised to make history While Bugatti has not disclosed an official price, informed estimates place the Brouillard between €10 million and €30 million. Context matters: a series Mistral begins near €5 million, while the Brouillard adds profound personalization, sculptural changes, and a pace of production that keeps scarcity front and center. In an arena where uniqueness drives value, the path to a brand record is unmistakably open. What it signals for the marque The Brouillard crystallizes Bugatti’s dual identity: traditional savoir‑faire intertwined with boundary-pushing performance. It exhibits a narrative soul—the white horse of Molsheim—woven into modern materials and world-class aerodynamics. As a rolling statement, it reaffirms that the Bugatti idea is larger than speed alone; it is about story, craft, and the courage to pursue an ideal to its logical limit.
Experts Warn: The Dangerous Blur Between Science and Wellness in Mental Health Bestsellers
A marketplace where labels blur In many bookstores, titles rooted in clinical science sit inches from glossy self-help guides promising instant serenity. That proximity can make rigorous research look interchangeable with lifestyle advice, especially when everything shares the same bright displays. Readers encounter a single aisle labeled “psychology,” even when the content ranges from peer-reviewed evidence to spiritual rituals. The result is a subtle but pervasive blur, turning a complex health landscape into a grab-bag of mixed claims. Why the shelves can mislead Retail categories are built for convenience, not for methodological clarity or clinical accuracy. When “development personal” or “wellness” becomes the default bin, evidence-based psychology competes with coaching manifestos and mystical manuals. The visual language of covers—calming color palettes, confident subtitles, glowing endorsements—flattens the distinction between randomized trials and anecdotal wisdom. In that aesthetic harmony, a guide on cognitive behavioral therapy may appear no more “serious” than a book on moon manifestation. The stakes for readers and patients Confusion carries real risks, including delayed care when people self-treat serious symptoms with untested routines. Vulnerable readers—facing depression, trauma, or anxiety—may be swayed by charismatic voices over careful data. Some messages frame recovery as pure willpower, which can amplify shame when symptoms persist despite effort. Others overpromise universal solutions, ignoring cultural context, diagnostic nuance, and comorbidity. “Shelving is not neutral; it shapes beliefs, expectations, and choices.” What professionals and retailers are asking Clinicians and public-health experts argue for clear, readable signage that separates science-based mental health from broader wellness. Books by licensed psychiatrists or psychologists that cite peer-reviewed studies could be grouped under “Evidence-Based Mental Health.” Adjacent space might host reflective memoirs, coaching workbooks, or contemplative philosophy—valuable in their way, but clearly labeled as non-clinical guidance. Booksellers emphasize their dual role as cultural curators and commercial actors, noting they respond to demand while striving for quality standards. How clarity could look and feel The goal is not to police ideas, but to help readers navigate with confidence. Transparent categorization respects reader autonomy while lifting the signal of credible practice. Clear tags—such as “scientific references,” “clinical overview,” or “personal narrative”—can work like map legends, turning a maze into a route. And when a book blends modes, hybrid labels can acknowledge both insight and limitation. A practical checklist for choosing wisely Check the author’s credentials: clinical license, academic affiliation, or relevant training. Scan the references: citations to peer-reviewed journals or reputable guidelines. Look for scope limits: clear statements about who the book is and isn’t for, and when to seek care. Seek methods, not miracles: approaches tested across diverse groups, with measurable outcomes. Watch the language: be wary of absolute claims, stigmatizing tones, or one-size-fits-all promises. Cross-verify with trusted bodies: national psychology associations or public-health agencies. The publisher’s responsibility Publishers can raise the bar by standardizing disclosure on methods, sample sizes, and limitations. Editorial policies could require conflict-of-interest statements, transparent citations, and plain-language summaries of evidence. Marketing should avoid medicalized framing for books that lack clinical validation, even when sales incentives press for bold claims. When a manuscript mixes reflection with research, honest jacket copy can prevent false equivalence. Coexisting without confusion Wellness writing can offer genuine comfort, perspective, and daily habits that support well-being. Scientific texts can provide structured tools, validated therapies, and realistic expectations for progress. The aim is to let these strands coexist, while giving readers the navigational cues to tell them apart. With clearer shelves, informed labels, and modest design tweaks, we can protect reader trust—and keep the aisle both inviting and intelligent.
“Déjà vu”: what scientists have discovered is even stranger! - Futura-Sciences
Human memory still holds many mysteries. While déjà vu is a relatively well known experience, its lesser known counterpart, jamais vu, remains largely unfamiliar to the general public. Yet this intriguing cognitive phenomenon could teach us a great deal about how our brain works. A recent study, published in September...
Five things America, and California, might not know about Gavin Newsom
Governor’s memoir reportedly offers revelations but also draws attention to details of Newsom’s early years that may have been forgotten.
Spring Sports: Know Before You Go
HICKORY, N.C. - Despite the winter weather, Lenoir-Rhyne Spring sports are about to be in full swing. Baseball hosts Columbus State for a three-game series this weekend while Men's Lacrosse takes on No. 2 Tampa in a showdown of national powers on Saturday. Softball opens up the home portion of their schedule on Wednesday, February 11, vs. Belmont Abbey. The final Spring sport to open the home portion of the their schedule will be Women's Lacrosse, who take on Rollins in Moretz Stadium on Sunday, February 22.
Could singing help people with MS? Louisiana patients find connection in a choir
Music activates multiple parts of the brain. For people with MS, a choir is exploring what singing together can offer.
Newsom, Shapiro and Other Democrats Whip Up the 2028 Book Buzz
A number of potential presidential candidates are releasing memoirs as the shadow primary heats up.
The Good Old Days of Sports Gambling
Recent memoirs by the retired bookie Art Manteris and the storied gambler Billy Walters provide a glimpse of an industry in its fledgling form—and a preview of the DraftKings era to come.
HHS Secy Kennedy Jr., Dr. Oz & Admin Officals Discuss Behavioral Health
Health and Human Services Secretary Robert F. Kennedy Jr., Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz, and others announce "Action for Progress," an initiative addressing mental health and addiction.
HHS Secy. Kennedy, Dr. Oz & Others Announce New Mental Health Initiative
Health and Human Services Secretary Robert F. Kennedy Jr., Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz, and others announce "Action for Progress," an initiative addressing mental health and addiction.
Gavin Newsom opens the oppo book in his new memoir
“Young Man in a Hurry” focuses on the personal more than the political, but Newsom’s likely 2028 run is the undeniable subtext.
Takeaways From Gavin Newsom’s New Memoir, ‘Young Man in a Hurry’
His introspective memoir tries to challenge the conventional wisdom about his upbringing, explores his marriages and airs a little dirty laundry — but says relatively little about politics.
Gavin Newsom Memoir Describes Difficult Childhood, Contrary to Image
Mr. Newsom, the California governor and a potential presidential candidate, writes that the privileged caricature of his background is mistaken.
‘It’s a substantial amount’: BCBS faces criticism over $800 refund delay for Oakland County couple
An Oakland County couple said they were over $800 out because Blue Cross Blue Shield of Michigan wouldn’t refund their overpayment.
Catherine O’Hara, ‘Home Alone’ and ‘Schitt’s Creek’ star, dead at 71
Catherine O’Hara, who starred in legendary films “Beetlejuice” and “Home Alone” before taking a star turn as Moira Rose on “Schitt’s Creek,” has died. She was 71.
Notre Dame loses to Cal on the road, 80-69
Notre Dame drops another ACC game to put its conference record at .500.
Josh Shapiro accuses JD Vance of giving 'comfort' to right-wing antisemitism
The Democratic governor of Pennsylvania, a potential 2028 presidential candidate, is on a book tour promoting his memoir, which highlights his Jewish faith.
Hearing on Veterans Affairs Health Care System
The Senate Veterans' Affairs Committee will hear testimony from Secretary Doug Collins on proposed changes to the department's health care system.
Singer "Kid Rock" & Live Entertainment Policy Advocates Testify on Concert Ticket Fees
Singer "Kid Rock," Live Nation Entertainment VP Dan Wall & entertainment policy advocates testify to a Senate Commerce subcommittee on ticket prices and fees.
Entertainment lawyer Dina LaPolt on fame, sobriety and her new memoir
New Paltz native Dina LaPolt reflects on growing up gay in a small town, conquering addiction and building a top-tier firm in a new memoir.
Review | Josh Shapiro’s memoir is heavy on inspiration, light on political substance
In “Where We Keep the Light,” the Pennsylvania governor focuses on his faith and a track record of working across party lines.
Science news this week: The world's oldest rock art, giant freshwater reservoir found off the East Coast, and the biggest solar radiation storm in decades
Jan. 24, 2026: Our weekly roundup of the latest science in the news, as well as a few fascinating articles to keep you entertained over the weekend.
Health Insurance CEOs Testify on Health Care Affordability
The House Ways and Means Committee holds a hearing on health care affordability with testimony from health insurance CEO's.
Miraculous Corp partners with Ground Control Entertainment to launch world’s first Miraculous Family Entertainment Center
HOLLYWOOD, Calif. — Miraculous Corp — the groundbreaking joint venture between Mediawan and ZAG and home to the beloved global franchise Miraculous: Tales of Ladybug & Cat Noir—has officially s…
Analysis: Trump’s Davos hosts might abhor him — but he’s worth listening to
Dean Acheson, the revered US diplomat, described his role as an architect of the post-World War II world in a blockbuster memoir called “Present at the Creation.”
Miraculous Corp Opens First Family Entertainment Center in Qatar
Miraculous Corp partners with Ground Control Entertainment to launch world's first Ladybug & Cat Noir center at Mall of Qatar in 2026.
In his new book, Gov. Josh Shapiro recalls an ‘offensive’ vetting process to be Kamala Harris’ running mate
In Shapiro’s memoir set to publish later this month, he recalls being asked by Harris’ vetting team if he had ever been “an agent of the Israeli government,” among other new details.
Shapiro says Harris’ vetting team asked whether he was ‘an agent of the Israeli government’
A number of forces on the left questioned Josh Shapiro’s ties to Israel during Kamala Harris’ rushed running mate selection process in 2024. In his new memoir out next week, the Pennsylvania governor says the former vice president and her vetting team were among them.
Josh Shapiro Writes That Harris Team Asked if He Had Ever Been an Israeli Agent
In his new memoir, the Pennsylvania governor suggests that when Kamala Harris’s team vetted him to be her running mate, aides focused on Israel to an extent he found offensive.
White House Science & Tech Policy Director Testifies on U.S. AI Strategy
White House Office of Science and Technology Policy Director Michael Kratsios testifies before a House Science, Space and Technology subcommittee on the administration's artificial intelligence (AI) strategy.
White House Science & Tech Policy Director Testifies on U.S. AI Strategy
White House Office of Science and Technology Policy Director Michael Kratsios testifies before a House Science, Space and Technology subcommittee on the administration's artificial intelligence (AI) strategy.
Business concerns as Abingdon reservoir consultation ends
Thames Water plans a £7.5bn reservoir to serve 15 million customers across south-east England.