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Rural health care providers can now apply for $50M to stabilize access - New round of health care funding builds on record $146M investment - Office of the Governor
SANTA FE – New Mexico’s rural health care providers can now apply for a share of $50 million in health care funding as part of the State of New Mexico’s three-year, $146 million investment that has helped recruit more than 800 health care workers to underserved communities. The funding comes from New Mexico’s Rural Health […]
Democrats’ long-shot bid to flip Alaska’s Senate seat
Democrats are hoping for an upset in Alaska’s Senate race. U.S. Rep. Mary Peltola, a Democrat, is trying to unseat Republican incumbent Sen. Dan Sullivan. We discuss the major issues at play, plus why Republicans are backing an effort to repeal Alaska’s ranked-choice voting system.This episode: voting correspondent Miles Parks, senior political editor and correspondent Domenico Montanaro, and Alaska Public Media Washington correspondent Liz Ruskin.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Brazil’s former president Bolsonaro allowed to serve 27-year sentence at home due to poor health
The decision follows Bolsonaro’s hospitalization for pneumonia, one of several health problems he has faced since he was stabbed by a man in 2018 before he was elected president.
Bolsonaro allowed to serve 27-year sentence at home due to ill health
The decision by Supreme Court Justice Alexandre de Moraes follows Bolsonaro’s hospitalization since March 13 for pneumonia.
Candle-Making Business Is the Latest Pop-Up to Join Downtown Revitalization Effort
Visitors on Saturday, March 28 can receive a free gift.
Melania Trump hosts world counterparts and tech reps to discuss children, education and technology
Melania Trump is calling on nations to work together to improve access to education and technology for children
Rubio plans travel to France to sell Iran war to skeptical G7 allies
Secretary of State Marco Rubio will travel to France this week to try to sell America’s skeptical Group of Seven allies on the Iran war that has sent global fuel prices soaring
Trump casts Florida mail ballot as he pushes Congress to severely limit that voting option
President Donald Trump has cast another mail ballot in Florida as he continues to publicly bash the voting method as a source of fraud and push Congress to curtail the practice
ENvue Medical Expands Presence within a Major Michigan Health System and Grows U.S. Hospital Footprint to 39
Premier 714-bed teaching hospital and Level I Trauma Center purchases ENvue™ Navigation Platform system and feeding tubesTYLER, Texas, March 24, 2026 (GLOBE NEWSWIRE) -- ENvue Medical, Inc. (NASDAQ: FEED) (“ENvue,” “ENvue Medical” or the “Company”), a medical technology company specializing in the advancement of intelligent, non-invasive solutions for enteral care across clinical and home care settings, today announced a purchase of the ENvue™ Navigation Platform and feeding tubes by a premier t
US democracy has settled into diminished state, experts find
Bright Line Watch researchers see stabilization in democratic health but at lower levels after sharp decline
Blount: Online sports betting proposal has little support in Senate, would cost casino industry
Sen. David Blount, chairman of the Gaming Committee in the Senate, says a proposal to legalize online sports betting lacks support in the Senate, and could harm the state's casino tourism industry, which provides thousands of jobs and millions in state revenue. Blount also discusses proposed, and recently enacted, changes to the Public Employee Retirement System, and proposals to increase tax credits for private schools.
Florida Democrats hope in special election to flip a state legislative district that includes Mar-a-Lago
Democrats in Florida are hoping to capitalize on the party’s recent special election overperformances and come out on top Tuesday in a special state House election for a Palm Beach district that includes President Donald Trump’s Mar-a-Lago residence.
Colorado’s Tamale Act may decide whether home cooks can build a business
An eclectic coalition, including the MAHA call for “food freedom,” gave the law a second chance as backers push for immigrant assistance and entrepreneurship.
Pete Crow-Armstrong, Chicago Cubs finalizing contract extension
CuSTEMized: Personalized Storybooks Inspire the Next Generation of Female Scientists
Custom books feature girls as STEM heroes, aiming to build their confidence and encourage them to pursue their scientific ambitions through storytelling and pictures.
Segment: Financing Action on Extreme Heat and Maternal and Newborn Health: The Way Forward
The segment “Financing Action on Extreme Heat and Maternal and Newborn Health: The Way Forward” will examine how innovative and better-aligned financing approaches can respond to these growing risks. Discussions will highlight country experiences in mobilizing domestic resources, opportunities to unlock and scale climate finance, and the role of heat-smart innovations in building resilient health systems. Particular attention will be given to low- and middle-income countries, where exposure and vulnerability remain highest, and where integrated solutions can deliver the greatest impact.
Former political rivals take on Trump’s push to nationalize voting
GOP lawyer Ben Ginsberg and former Obama White House counsel Bob Bauer aim to present a united front against the Trump administration’s efforts to oversee election administration
The Best Restaurants to Book in Hong Kong Right Now
Highlights include a value restaurant specializing in premium Hanwoo beef and a new yakitori counter atop a skyscraper.
Formulating a Future: Finding a Calling in Pharmaceutical Science | Oberlin College and Conservatory
Chemistry major Alex Xie ’26 utilizes CELA’s research fellowships and scholarship advising to transition from campus labs to a future in pharmaceutical research.
Microsoft Realizes It’s Epically Screwed Up Windows 11 as Users Rage at Copilot AI Crammed Everywhere
Windows VP Pavan Davuluri effectively admitted outright that the company went too far to shove AI down users' throats at all costs.
Building a Culture of Health: BJACH Opens Armed Forces Wellness Center at Fort Polk
FORT POLK, La. — Bayne-Jones Army Community Hospital marked a significant step forward in supporting warfighter readiness and community well-being with the grand opening of its new Armed Forces Wellness Center on March 23. The center, located on the first floor inside BJACH, provides Soldiers, Families, civilian employees and beneficiaries with access to personalized health assessments, education and coaching designed to improve overall health and performance.
Stealth BioTherapeutics Announces MRC Business Engagement Fund Grant to Advance Mitochondrial Disease Research
/PRNewswire/ -- Stealth BioTherapeutics (the "Company"), a commercial-stage biotechnology company focused on the discovery, development, and commercialization...
2026 NFL mock draft: Surprises in top 10 of latest first-round projection
The 2026 NFL Draft is just a month away, and our latest mock draft features a few surprises materializing in the top 10 picks.
Rahm Emanuel proposes banning all federal employees from betting on prediction markets
Rahm Emanuel is proposing a far-reaching measure to crack down on betting in predictive markets in Washington as part of an effort to call attention to what he sees as a culture of corruption gripping the nation’s politics
Fertilizer prices bring more pain for American farmers amid war in Iran
The war in Iran is pushing up prices for already-strained farmers, with higher costs for fertilizer and energy on top of last year’s tariffs. And the increasing pressure on American agriculture could lead to even bigger price tags at the grocery store.
Dr Liz O'Riordan: Women's health must be taken more seriously
Dr Liz O'Riordan says it is important women seek help from professionals not "Google and Chat GPT".
Precision Nutrition: Tufts University Expert Q&A On How Personalized Diet Science May Transform Health - Where The Food Comes From
Tufts expert José Ordovás explains precision nutrition and how personalized diet science could transform health and prevent disease.
Man who bought $75 worth of Apple products from a stranger in a car park realizes he might be sitting on a small fortune
A tech enthusiast who bought a bunch of used Apple products off a stranger in a car park was left pleasantly surprised by the haul
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Syracuse finalizing Gerry McNamara hire: Siena coach helped lead Orange to 2003 national championship
McNamara just finished guiding Siena to the NCAA Tournament, where it almost upset No. 1 Duke
Rising toll: Are NC sports betting protections enough?
With two years of legalized sports betting in the books, public health advocates, researchers and counselors suggest changes.
New Apple TV and HomePod Mini Remain 'Ready' to Launch
Apple has unveiled nine new products this month, but the wait continues for the next-generation Apple TV 4K and HomePod mini models. In his Power On newsletter today, Bloomberg's Mark Gurman said new versions of the Apple TV and HomePod mini have been "ready" since last year, but he reiterated that Apple has held off on releasing them until the more personalized version of Siri and other Apple Intelligence upgrades are released later this year.
Tantalizing Tech: The Goodies at Cyclingworld Europe 2026
Turbulence at Eurobike has led to a big boost for Cyclingworld. Here's some of the latest dream tech from the show.
Neighbors say Indian Springs revival could do KCK ‘more good than that stadium’
Area businesses said they want to see the project revitalize the State Avenue business corridor near I-635.
Bill Self health scare, explained: Why Kansas coach was hospitalized during 2025-26 season
Bill Self was briefly hospitalized after experiencing symptoms related to heart problems he has dealt with in the past.
Health Literacy as a Modifiable Clinical Risk Factor: Operationalizing an Underrecognized Determinant of Outcomes
Health literacy has been considered a social determinant of health and has never been extensively incorporated in the general practice of clinical care. Systematic reviews and cohort studies sho...
Super PAC spending passes $200M, with some groups hiding their cause
Groups that include pro-Israel organizations obscured their spending in some midterm races to try to defeat candidates that oppose their cause.
Doctors are in: Stuffed animals get health checks at zoo's Teddy Bear Care Fair
Toddlers Eliza and Olivia Altman watched attentively as Toledo Zoo & Aquarium volunteers performed “surgery” on their nearly decapitated stuffed animals ...
Rockets to utilize tweaked starting lineup vs. Heat
Rockets to utilize tweaked starting lineup vs. Heat
Ole Miss eyes May decision on VaughtHemingway entertainment district partner
Athletics director Keith Carter provided an update and timeline to the Vaught-Hemingway entertainment district project that plans to utilize a public-private partnership.
Congress could be headed for a tipping point, irreversible decline
After nearly two decades covering Capitol Hill, a reflection on how bad things are.
With casino empire gone, Trump family bets on prediction markets
With his Atlantic City casinos in duress in the 1990s, Donald Trump saw a potential lifeline in sports betting and aggressively campaigned to legalize it in New Jersey. But when state powerbrokers shut him down, Trump vowed that he’d eventually find a way to win.
Health Ministry: 303 people hospitalized in war with Iran and Hezbollah in past 24 hours
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Rivian and the danger of building a business on government largesse
The EV market is evolving to survive without public subsidies.
Senate Democrats wade into their party's most contentious primaries: From the Politics Desk
Plus, more mixed messaging from the Trump administration on Iran.
The State That Decided to Topple a Political Giant
Phil Berger has been the most powerful person in North Carolina for 15 years. That wasn’t enough to save him from voters’ anger at incumbents and legalized gambling.
Brazil’s finance minister Haddad resigns to launch a high-stakes bid for Sao Paulo governor
Brazil’s finance minister Fernando Haddad has resigned to launch a bid for São Paulo governor
Value investors see mispriced opportunities from sports to fertilizer
Value investors pitched a mix of stock ideas in disparate corners of the market at the Value Invest conference in New York on Thursday.
Chuck Norris, action hero and ‘Walker, Texas Ranger’ star, has died
Chuck Norris, veteran, martial arts world champion, action hero and early 2000s Internet meme inspiration, whose rugged demeanor was immortalized on hit show “Walker, Texas Ranger,” has died.
3 Democratic pastors in Iowa are running for Congress, a snapshot of a national trend
More Democrats are openly running on faith, as progressive clergy and other religious candidates push back on the idea that Christianity belongs to the right
Why Mamdani’s faith matters
New York Mayor Zohran Mamdani takes his Muslim identity seriously — so should we.
Small businesses reeling from tariffs brace for spiking oil prices
Anxiety has pulsed through the small-business economy for months, even before the war in Iran began weighing on energy prices.
Rising toll: Are NC sports betting protections enough?
With two years of legalized sports betting in the books, public health advocates, researchers and counselors suggest changes.
Judge rules US government overreached with transgender health care declaration
A federal judge has ruled that the government overreached when it declared certain types of gender-affirming care unsafe for young people
4 flight attendants injured on Delta flight to Sydney after plane experiences 'brief turbulence'
Four Delta Air Lines flight attendants were injured during turbulence on a flight bound for Sydney, with three hospitalized but no passengers hurt.
The Big Dance brings action to Downtown St. Louis, as city leaders move to finalize sports and entertainment district
St. Louis is feeling March Madness. It’s not just the games taking place on the court in the Gateway City; the Saint Louis University men’s basketball team drew many eyes Thursday night as the Billikens faced Georgia in the NCAA tournament.
The Big Dance brings action to Downtown St. Louis, as city leaders move to finalize sports and entertainment district
St. Louis is feeling March Madness. It’s not just the games taking place on the court in the Gateway City; the Saint Louis University men’s basketball team drew many eyes Thursday night as the Billikens faced Georgia in the NCAA tournament.
Anthropic just shipped an OpenClaw killer called Claude Code Channels, letting you message it over Telegram and Discord
The consensus among early adopters is that Anthropic has successfully internalized the most desirable features of the open-source movement—multi-channel support and long-term memory
Political influence ‘a serious problem’ for FDA under Trump, former commissioner says
Hundreds of individualized treatments for rare diseases could become available over the next decade — but only if government regulators handle the new
Markiplier to Microdramas: The Ankler x NAB Show’s Future of Entertainment
Share Subscribe Vegas, baby! The Ankler is heading back to NAB Show for a second year in a row — and doubling down on conversations with the smartest people in the industry. From April 18–22, we’re partnering again with the industry’s biggest media and tech gathering to break down the Business of Media and Entertainment as it’s actually evolving: faster, riskier and increasingly driven by new formats, new audiences and new power players. This curated series will bring together top creators, executives and innovators to tackle the forces reshaping the industry — from the AI disruption of Hollywood’s creative ecosystem to the rise of the creator economy, shifting audience behavior and the changing economics of production. We’ll be rolling out more programming in the coming weeks — including top speakers from leading AI studios, prediction markets and beyond — so keep an eye on the Business of Media and Entertainment hub. But first up, we’re announcing two panels about what’s actually working in Hollywood: The Scary-Smart Business of Horror A good scare has become one of the entertainment economy’s most reliable engines. With disciplined budgets, built-in fandoms and global box office upside, horror consistently outperforms. From theatrical releases to streaming-first originals and creator-driven IP, the genre is artistically flexible and financially durable — and one of the last truly communal experiences for Gen Z and Gen Alpha audiences. Join YouTube creator Mark Fischbach, aka Markiplier, whose independent feature Iron Lung earned more than $50 million at the global box office, Atomic Monster president Michael Clear and screenwriter Akela Cooper (M3GAN, Malignant) for a conversation moderated by Like & Subscribe’s Natalie Jarvey about why horror travels so effectively across platforms and borders, how studios and independents are building sustainable genre pipelines and why the next wave of breakout franchises may emerge from unexpected sources. Inside the Microdrama Boom Short-form serialized storytelling is having a major moment. Microdramas, social-native series and creator-led narratives are capturing massive audiences with low-cost, rapid production cycles and direct-to-fan distribution. What was once dismissed as niche or experimental is now attracting major platform investment. Moderated by Jarvey, this panel of microdrama creators and executives — including one of the format’s top stars and producers, Kasey Esser, and Dhar Mann Studios’ head of vertical content, Erin McFarlane — examines how format innovation, fandom dynamics and algorithmic discovery are reshaping the economics of scripted storytelling and what traditional studios can learn from these agile models. For sponsorship opportunities, contact Lynne@theankler.com Share
Packers coach Matt LaFleur finalizes his staff moves for 2026
Green Bay's new quarterbacks coach is Luke Getsy, a former Las Vegas Raiders and Chicago Bears offensive coordinator who spent last season as a Packers senior assistant. Getsy previously was Green Bay's quarterbacks coach from 2019-21. The Packers also hired Scott Fuchs as a defensive analyst, T.C. McCartney as offensive quality control coach and Will Smart as a defensive quality control coach.
Maxx Crosby Trade Attempt Shows Ravens’ New Aggresive Strategy
The Baltimore Ravens rarely chase blockbuster trades, but their pursuit of Maxx Crosby suggested a different level of urgency. The trade suggested an “all in” motto from a franchise that is known for patience and draft-driven roster building. The deal ultimately fell apart before it could be finalized. Even so, the attempt revealed a willingness […] The post Maxx Crosby Trade Attempt Shows Ravens’ New Aggresive Strategy appeared first on The Lead.
Treasury Secretary Bessent unveils plan to flood market with oil amid Iran war
Treasury Secretary Scott Bessent joins ‘Mornings with Maria’ to discuss the Iran war, surging oil prices, market volatility, Fed uncertainty, Powell’s future and the U.S. strategy to stabilize the global economy.
Dan Nelms
I realized Stanford GSB could help round out my skill set and prepare me to be an executive for a growth startup.
Sangamon County voters approve new tax increase for mental health board
Murphy explained that the mental health board would act as a centralized organization that helps coordinate groups and providers in the Sangamon County area.
Republicans are ramping up attacks on Muslims
Past GOP leaders, including George W. Bush, spoke out against Islamophobia. Now it is going unchallenged.
Vance is in a bind, supporting a war that could cost him politically
People close to JD Vance concede that a long conflict will be a challenge for the next GOP nominee but say the vice president hasn’t made up his mind about running.
Analysis | What to know about Trump’s Homeland Security pick
Sen. Markwayne Mullin isn’t backing down from mass deportations.
Where big spending won – and lost – in the Illinois primary
Illinois Democrats ushered in a new generation of lawmakers Tuesday night, picking five new nominees for Congress in open seats that are favored to remain in Democratic hands this fall
WNBA CBA talks show execs still don't take women seriously. Do they like losing?
WNBA reaches new contract only after owners realized players knew their worth and weren't going to accept less.
FNC acquires McPherson-based farm management business
Farmers National Company has acquired a Kansas-based farm management division to help provide sustainability for ag operations. FNC says the purchase from Peoples Bank and Trust in McPherson, Kansas, will give producers access to specialized management, local knowledge, and resources to help maintain profitability for producers. Grant Fitzgerald, Senior Vice President of Farm and […]
SHINOBI: Art of Vengeance DLC ‘SEGA Villains Stage’ launches April 3 alongside free update
SHINOBI: Art of Vengeance downloadable content “SEGA Villains Stage” will launch on April 3 for $9.99 alongside a free update, publisher SEGA and developer Lizardcube announced.
This overlooked organ may be more vital for longevity than scientists realized
The role of the thymus in our long-term immunity and health is poorly understood. A new study suggests we need to pay attention
TNA WRESTLING AND EUROSPORT INDIA ANNOUNCE NEW MULTI-YEAR EXCLUSIVE PROGRAMMING AGREEMENT
The Deal Includes the Popular Localized Hindi-Language Series ‘Pehlwani Patakha’, as well as Exclusive TNA+ Specials & Iconic Content from TNA’s Expansive Library Boasting Classic Matches from Some of the Sport’s Most Legendary Figures
Lisa Kudrow says early reality TV signaled 'the end of civilization'
Lisa Kudrow has called 'Survivor' winner Richard Hatch 'despicable' and admitted she was horrified by reality TV behavior in the medium's early days: 'The end of civilization.'
The Paleo Diet Never Existed. Scientists Found What Early Humans Were Really Eating.
Humans are actually limited in how much protein they can metabolize for energy, meaning early humans really needed a more well-rounded diet to survive.
Milwaukee's Walker's Point gets new indie game store
Tabletop Bookshelf, a new indie game store specializing in unique role-playing games, opens its first physical location in Milwaukee.
How lawyers got their hands on thousands of private patient records
The nation’s largest health records company, Epic Systems, has sued multiple firms including GuardDog Telehealth, alleging they had improperly accessed personal medical records.
These 5 states still penalize you if you don't have health insurance
Even though the federal penalty for not having health insurance ended, five places still charge residents a fee.
Five new cases of meningitis in Kent, UK Health Security Agency confirms
Two people have died in the outbreak - a 21-year-old university student and Juliette, a sixth form pupil at Queen Elizabeth's Grammar School in Faversham.
Colorado lawmakers want to rein in sports betting
The legislation acknowledges an increase in problem gambling since the state legalized it in May 2020.
Do Diet Trends Improve Health? A Clinical Take
Learn which diet trends have scientific support — clean eating, detox, glow food and plant-based diets influence health differently and require individualized clinical counseling.
Wisconsin Senate passes bills to legalize online sports betting, establish college athlete NIL rules
The Wisconsin Senate on Tuesday passed bills to legalize online sports betting and create rules for college athlete NIL payments.
Legislation legalizing online sports betting passes Wisconsin Senate
Online sports betting could soon be legal in Wisconsin under a bipartisan bill on its way to Gov. Tony Evers' desk.
Pappas Statement on Passage of Legislation to Fund Critical Small Business R&D Programs
Today, Congressman Chris Pappas (NH-01) helped pass the bipartisan Small Business Innovation and Economic Security Act to reauthorize the Small Business Innovation Research (SBIR) program and the Small Business Technology Transfer (STTR) program for five years. The SBIR and STTR programs provide competitive awards to American small businesses to conduct research and development projects that have the potential for commercialization.
Space Needle, Pacific Science Center finalize $17M property purchase
This week, owners of the Space Needle closed on the $17.25 million purchase of 21% of Pacific Science Center's property.
Now everyone in the US is getting Google’s personalized Gemini AI
Suggestions based on what’s in your Gmail inbox or YouTube viewing history.
Billy Porter Gives Tearful Health Update on TODAY: 'Gift to Be Alive'
The "Cabaret" star says it's "a gift to be alive" after a frightening hospitalization in 2025.
Donations to science often avoid scrutiny. Jeffrey Epstein used this to his advantage
Billions of dollars are invested in science every year through philanthropy, with little legal or public scrutiny. Jeffrey Epstein utilized this to cultivate scientists and launder his reputation.
Legalized online sports betting faces pushback before key vote
Opponents of a bipartisan bill to legalize online sports betting in Wisconsin continue to push back as the proposal is set for a vote in the Senate.
The glaring problem with RFK Jr.’s push for more nutrition education
Teaching doctors in training about nutrition will do little if patients cannot access healthy food.
Could a ‘digital twin’ help you get better health care?
Scientists are working to create "digital twins" of patients that they can test treatments on, in hopes of delivering personalized health care.
Back to Dresden: Lin Dunn's grit in fight for women's sports was baked in South
IndyStar visited basketball legend Lin Dunn in her hometown Dresden, Tenn., where she first realized life wasn't always fair for women in sports
Southeast Asian Fuel Prices Destabilize Politics
Indonesia, for one, has a bloody history of fuel-related riots.
University of Florida Penalizes GOP Group Over Antisemitism Accusations
After the University of Florida restricted the Republican organization from operating on campus, the group sued the university arguing its First Amendment rights were violated.
Jacksonville Jaguars eyeing a specific position in the NFL Draft
After the NFL’s new league year opened Wednesday, teams finalized a wave of free-agent signings and trades. Now the league’s focus shifts toward the 2026 NFL Draft. Teams will host dozens of prospects throughout March and April while continuing their…
OpenAI to cut back on side projects to focus on core business, WSJ reports
ChatGPT-maker OpenAI's top executives are finalizing plans for a major strategy shift to refocus the company around coding and business users, the Wall Street Journal reported on Monday.
AG Letitia James pushes bill to ban 'surveillance pricing'
Using personal data like browsing history and more, Instacart charged individualized prices for items unbeknownst to customers, according to data.
Hilary Duff defends her mother Susan after Frankie Muniz called her a 'super intense’ stage mom during the 'Lizzie McGuire' days
Hilary Duff defends mother Susan after Frankie Muniz labeled her ‘super intense’ stage mom: ‘I was never pushed into acting.'
Merlin and Inflection Point Acquisition Corp. IV Announce Closing of Business Combination
Merlin's Cessna Caravan Merlin's aircraft flying overhead at the company's Quonset, RI hangar Merlin's Quonset, RI Hangar A C-130J flying overhead at Merlin’s Quonset, RI hangar Transaction provides more than $200M in gross proceeds to accelerate commercialization of AI-powered autonomous aviation Merlin to Begin Trading on March 17th on the NASDAQ Under Ticker Symbol “MRLN” BOSTON, March 16, 2026 (GLOBE NEWSWIRE) -- Merlin, Inc., an aerospace and defense technology company building the operatin