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‘Project Hail Mary’ blasts off with $80.5 million, a best for Amazon MGM, and the year
Studio estimates on Sunday say Amazon MGM's “Project Hail Mary” has topped the North American box office charts with $80.5 million in ticket sales — the second biggest ever for a non-franchise film.
Acadiana business owner Walter ‘NuNu’ Broussard dies
A well-known Acadiana business owner and community figure has passed away.
iRacing on Vision Pro bringing 'immersion and fidelity never before seen in sim racing'
iRacing on Apple Vision Pro will bring a “level of immersion and fidelity never before seen in sim racing,” says...
Phillies pitcher Daniel Robert stable after second medical emergency in six months
Daniel Robert suffered a cardiac event Sunday — the second in six months — but was stable after his defibrillator activated
Student researchers bring Kentucky State University science to Posters-at-the-Capitol
With lawmakers just steps away, three Kentucky State University undergraduates presented research on cattle health, soil amendments and food safety at the Capitol Annex on March 5, bringing student-led agricultural […]
Israel Thought It Could Spur Rebellion Inside Iran. That Hasn’t Happened.
President Trump’s hopes that an Israeli plan to ignite an internal uprising against Iran’s theocratic government could bring the war to a swift end have so far been dashed.
Chappell Roan pushes back after soccer star Jorginho alleges his daughter was mistreated
Chappell Roan pushes back after a Brazilian soccer player says a guard mistreated his young daughter at a hotel. Jorginho says his 11-year-old recognized Roan at breakfast in São Paulo and got...
City of Paducah Finance Department to host informational workshop on Business License Renewals
In case you missed it, the City of Paducah Finance Department will host an informational workshop on Business License Renewals for local business owners at the McCracken County Library tomorrow,
The Times' top 25 high school baseball rankings
St. John Bosco and Sherman Oaks Notre Dame remain unbeaten in high school baseball
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Buffalo Museum of Science celebrates 50% completion of upcoming Science Stadium Exhibit
The Buffalo Museum of Science marked a major milestone in its $3 million Science Stadium exhibit, announcing on March 20 the project is now 50% complete ahead of its planned
Business briefs: PNW honors doles out honors on Founders Day
News and events around the area
NCAA men's bracket live updates, scores: Purdue vs. Miami leads off March Madness Sunday; Duke, Florida, UConn return to court
Breaking down Bills’ selections in latest NFL mock drafts
According to the latest NFL mock drafts, the Bills could go wide receiver, linebacker, safety, or defensive linemen at pick 26.
Bucket hats and home run chains: Getting decked out for baseball season at Poor Boys Sports
From shirts featuring new players to hats in every color, Poor Boys Sports has all your Orioles merch needs for Opening Day.
3 restaurants open in Pittsburgh’s East Carson business district
Pittsburgh city leaders celebrated the opening of three new restaurants in the city’s East Carson business district on Friday.
Tom Steyer explains why he should be California's next governor
Tom Steyer sat down for an interview with California Politics 360 for a wide-ranging conversation on his run to be the state's next governor.
Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"
California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.
Crimson Desert Dev Breaks Silence Admitting AI Art Was Used
Developers Pearl Abyss apologize for their inclusion and promises to replace its slop with new art.
Team USA flag football team should consider these 12 NFL stars ... but not Tom Brady
These NFL players should consider making a run at Team USA inclusion in order to earn the first football gold medal in Olympics history.
Capcom celebrates Resident Evil's 30th anniversary by promising "even more wonderful experiences" are coming, but doesn't confirm when
Resident Evil series executive producer, Jun Takeuchi, has written to Resident Evil players across the world, thanking …
The Cincinnati's Favorite Beer 2026 winner is ... (drumroll please)
Our new beer bracket champ had a difficult path to the crown. The final suds match was Vlad (Fretboard) vs. Dunkel (Hofbrauhaus). So, who won!?
Fitchburg Public Library hosts Wisconsin Film Festival preview
FITCHBURG, Wis. — The 28th Wisconsin Film Festival is coming up in just a few short weeks, and a local library is helping get the word out.
VoidStealer malware steals Chrome master key via debugger trick
An information stealer called VoidStealer uses a new approach to bypass Chrome's Application-Bound Encryption (ABE) and extract the master key for decrypting sensitive data stored in the browser.
Bash: Trump celebrating Mueller’s death ‘not a surprise, but that doesn’t make it okay’
Natrona County health and food inspections (3/13/26–3/19/26)
CASPER, Wyo. — The Casper-Natrona County Health Department inspects restaurants, grocery stores, convenience stores, mobile food units, commissaries and
Rising toll: Are NC sports betting protections enough?
With two years of legalized sports betting in the books, public health advocates, researchers and counselors suggest changes.
Purdue vs Miami live updates: Prediction, how to watch March Madness Round 2 game
Braden Smith has the NCAA assists record, now he can focus on his main goal: a championship. Miami stands in Purdue's way in Round 2 of March Madness.
Inside a rare lab that's blazing a bold trail as it hunts for new drugs
A scientist from Zambia who loves — LOVES! — chemistry runs a lab in South Africa that is being hailed for "extraordinary" work.
Inside a rare lab that's blazing a bold trail as it hunts for new drugs
A scientist from Zambia who loves — LOVES! — chemistry runs a lab in South Africa that is being hailed for "extraordinary" work.
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show, and stuck closely in...
\'Saturday Night Live UK\' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews. The first episode of “SNL UK” was hosted by Tina Fey, a veteran of the American show,
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews.
'Saturday Night Live UK' aims to take a comedy hit across the pond. The first verdicts are in
A British version of “Saturday Night Live” has debuted to largely positive reviews.
'Everybody Loses' author discusses the meteoric rise of sports gambling
Two years ago, Americans bet $120 billion on sports, a 27% increase from the previous year. That figure grew to $150 billion in 2024. Journalist Danny Funt investigates what's considered one of the most consequential — and least scrutinized — shifts in modern American sports in his new book, "Everybody Loses: The Tumultuous Rise of American Sports Gambling."
Titans sign ex-Browns linebacker
The Titans have signed former Browns linebacker Mohamoud Diabate to a contract after he wasn't tendered as an RFA.
4 tips for buying a home in a tough market, from the Property Brothers
Drew and Jonathan Scott, AKA The Property Brothers, have a new HGTV show where they guide buyers in a tough market. Here are their best tips.
Intel compares Core Ultra 200S Plus to Ryzen 9600X and 9700X, gaming uplift stays small
Intel Core Ultra 200S Plus is aimed at creators, not gaming Intel has updated its pre-briefing deck ahead of Core Ultra 200S Plus reviews, and one of the
Scientists discover surprising brain trigger behind high blood pressure
Scientists have uncovered a surprising brain-based trigger for high blood pressure, tracing it to a small region in the brainstem that normally controls breathing. This area, which kicks in during forceful exhalations like coughing, laughing, or exercise, also appears to activate nerves that tighten blood vessels—raising blood pressure. When researchers switched off this region in experiments, blood pressure dropped back to normal, suggesting it plays a direct role in hypertension.
This floating time crystal breaks Newton’s third law of motion
Scientists have created a new kind of time crystal using sound waves to levitate tiny beads in mid-air. These particles interact in a one-sided, unbalanced way, breaking the usual rules of motion and creating a steady, repeating rhythm. The system is surprisingly simple yet reveals complex physics with big implications. It could help advance quantum computing and deepen our understanding of biological timing systems.
UF students celebrate ‘women supporting women’ through new mental health group
According to the Healthy Minds Network’s data interface, a little more than one in three female college students suffered from anxiety in 2025, compared to a little under one in four male students.
Scientists Startled by What Happens When They Point Hubble at Comet
An extraordinary coincidence occurred when astronomers pointed the Hubble Space Telescope at a wayward comet.
Boys' basketball coach of the year: Mike LeDuc of Damien
The second-winningest coach in California high school history guided Damien to the state Division I championship.
In Maine’s marquee Senate primary, Janet Mills reaches out to women by raising Graham Platner’s online past
Janet Mills and her allies are counting on a gender gap to narrow Platner’s wide lead ahead of the June 9 primary to decide who will face incumbent Republican Sen. Susan Collins. They are betting that the unfiltered style that has brought Platner widespread attention as someone who could help Democrats reach young men will backfire with women.
Thank God for Wyoming — the un-Colorado
Years ago, I interviewed a Canadian health-care broker whose job was helping his countrymen escape their own failing system. When their “free” health care turned into “free to wait until you die,” he’d save his clients by routing them to doctors in the U.S. who’d accept cash and rescue their lives. I asked him what […]
Girls' basketball coach of the year: Alicia Komaki of Sierra Canyon
She came up with a winning formula to defeat Etiwanda and No. 1 Ontario Christian in the Southern Section Open Division championship.
A tribute to Scott Ostler, columnist, colleague, friend and sports wit
In Bruce Jenkins’ experience, there was never a teammate quite like fellow San Francisco Chronicle columnist Scott Ostler, who retired last week.
Lancaster County public sales: March 22, 2026
Beiler-Campbell Auction Services conducted a public auction of real estate March 9 for Stanley and Debora Miller at 2788 N. Colebrook Road, Manheim. A four-bedroom house with attached garage and
The Times' 2025-26 All-Star boys' basketball team
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The Times' final top 25 high school boys' basketball rankings
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I'm glad my daughter was rejected from an Ivy League college
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Southland girls' basketball final rankings for 2025-26 seaosn
A look at the top 20 high school girls' basketball teams in the Southland, led by Open Division state champion Ontario Christian.
Four truths about covid that have become clouded over time
In the early days, the virus posed a graver threat to people and the health care system, Trump embraced lockdowns he now blasts, and the benefits of vaccines were oversold.
Column: Republicans fearing a midterm rout revive Islamophobia as political strategy
The latest twist on replacement theory is the idea that white Americans are in need of saving from dark-skinned "others."
FYI BR: Here are the upcoming Holi and Easter festivities in Baton Rouge
Plan for pictures with the Easter Bunny, festivities at the LSU Rural Life Museum and more.
Game Preview: Carolina Hurricanes @ Pittsburgh Penguins 3/22/2026
Who: Carolina Hurricanes (44-19-6, 94 points, 1st place Metropolitan Division) @ Pittsburgh Penguins (35-18-16, 86 points, 2nd place Metropolitan Division) When: 3:00 p.m. eastern How to Watch: Locally broadcast on Sportsnet Pittsburgh and FDSN South, streaming on ESPN+ Pens’ Path Ahead: Quality opponents await in the next week; the Pens host Colorado on Tuesday, an Avs team […]
How investors use the BRRRR strategy to scale real estate portfolios
"My strategy is basically to use every property to fund the next one," said one real estate investor.
See what students from New Hampstead High wore for their 2026 prom
Students from New Hampstead celebrate their 2026 high school prom at Red Gate Farms.
Outgoing MSPs leave Holyrood with relief, regret and unfinished business
A record 42 MSPs are stepping down, from grandees to first timers - they share their reasons why.
AI may be helping more people start their own businesses, but without many employees
The 21-year-old cofounders of one startup said they are bringing in $1 million per month with 13 employees thanks to AI.
Flexitarian and the MIND included in top diets for a healthy brain, according to U.S. News
Discover four top diets that may support sharper focus, steadier mood, and long-term brain resilience
‘We can create hype’: H&M’s UK boss on its commitment to the high street
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Bill Self health scare, explained: Why Kansas coach was hospitalized during 2025-26 season
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'Education and communication key to voter turnout' in Jersey
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'Heartbreaking' - fighter pay debate laid bare at UFC London
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Are AI tokens the new signing bonus or just a cost of doing business?
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The Antidote to Our Growing Crises Must Transcend Politics
Each day, the challenges in our nation pile up. In just recent weeks, there has been the ongoing war in Iran and the Middle East, and ongoing debates about the growing negative impact of the Internet, looming AI challenges, and the Epstein files. The anticipation of divisive, even ugly, midterm elec...
One Of Resident Evil's Fundamental Joys Is Watching Beautiful Men Get Hurt
The people love Leon Kennedy for more than his action-game pedigree.
Are pretzels a healthy snack? Here's what dietitians say
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Recap: Sporting KC suffers 4-1 loss to Colorado
Sporting Kansas City suffered a 4-1 loss to the Colorado Rapids on Saturday at Sporting Park. Shapi Suleymanov scored the lone goal for SKC in the defeat as the visitors prevailed behind a brace from Paxten Aaronson to go along with a goal from fellow Designated Player Rafael Navarro and
Nebraska survives near-miracle heave at buzzer to advance past Vanderbilt, keep dream season alive in thriller
As War Disrupts India’s Gulf Ties, Economy Faces ‘New Broadside’
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Teaching Health Through Food: Kayla’s Passion for Nutrition
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Marc Abrahams, founder of the satirical Ig Nobel Prizes: ‘Scientists in the US are very angry. People are waking up’
The awards are moving to Switzerland, because their founder believes he can no longer guarantee the laureates’ safety in the United States
Bridging medical realities in the study of technology and health
Anthropologist and MIT Associate Professor Amy Moran-Thomas studies medical technologies and how they fail to reach some communities. “What anthropology has to offer the world, and other knowledge systems, is the insights of people that might be missing from many accounts,” she says.
Spring (Sports) Have Sprung!
QHS takes down QND in Baseball, QND falls to Helias in girls' soccer, and QU falls to UMSL in baseball.
Nebraska survives near-miracle heave at buzzer to advance past Vanderbilt in thriller, keep dream season alive
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Black Family Wellness Expo brings people together for day of health education
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High school baseball and softball: Saturday's scores
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Lakers player grades: Luke Kennard gives L.A. ninth straight win
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4 Takeaways From Fanatics Flag Football Classic: USA Football Dominates the Pros
Tom Brady looked the part in his return to the field, but USA Football overwhelmed their NFL counterparts in the Fanatics Flag Football Classic.
Trump’s Reaction to Mueller’s Death: ‘Good, I’m Glad.’
The president has consistently celebrated the deaths of political foes. His response to Mr. Mueller’s death drew criticism from Republicans and Democrats.
Arizona Cardinals GM perhaps gave hint about Michael Wilson's future
We compare what Monti Ossenfort said this offseason about Michael Wilson with what he said about Trey McBride last year.
Amanda Peet Shares Breast Cancer Diagnosis
Amanda Peet detailed her recent breast cancer diagnosis in a new essay, sharing that her health battle coincided with both of her parents' final months in hospice care.
Kings fall 4-1 to Sabres amidst playoff push
The Los Angeles Kings fall short to the Buffalo Sabres in a 4-1 loss Saturday at Crypto.com Arena. Artemi Panarin would score the Kings' lonesome goal, but it was no match for Buffalo's four goals by four different skaters. The Kings stand in the third place Wild Card spot at 28-25-16 and 72 points.
Brooks Nader, 29, Reveals She Had Liposuction ‘Years Ago’ and Regrets It: ‘I Just Didn’t Need It’ (Exclusive)
The model and reality star tells PEOPLE that she experienced unwanted side effects from the procedure
COLUMN: Frager punches Nebraska men’s basketball’s ticket to Sweet 16
Yes, this is real. It isn’t a dream or a movie. The Huskers are moving on to the Sweet 16 in Houston next week.
UCLA overcomes broken tooth and stubborn UCF 75-71
UCLA remains in the hunt for a 12th national championship
Friction without contact discovered as magnetic forces break a 300-year-old law
Researchers have uncovered friction without contact—driven entirely by magnetic interactions. As two magnetic layers slide, their internal forces compete, causing constant rearrangements that dramatically increase resistance at certain distances. This creates a surprising peak in friction instead of a steady rise, breaking a long-standing physics law.
Dana Walden unveils leaders of expanded Disney Entertainment
Dana Walden, the incoming President and Chief Creative Officer of The Walt Disney Company, has unveiled the new leadership structure for Disney Entertainment, bringing together the company’s streaming, film, and television businesses along with its games and digital entertainment division.
Mapping a career in electron microscopy
Nature Reviews Chemistry - Ahead of his 60th birthday, Paul A. Midgley, Professor of Materials Science at the University of Cambridge, discussed his life in science.
‘They want to colonise us’: Brazil’s Lula warns of foreign interference
The left-wing Brazilian president is critical of US actions throughout Latin America, though he does not name Trump.
LeBron James breaks record for most NBA games played
LeBron James broke the NBA record for most regular-season games played on Saturday, taking the court for his 1,612th when the Los Angeles Lakers tipped off against the Orlando Magic.James, playing his unprecedented 23rd season, already holds a host of NBA records, including points scored, field goals made and field goals attempted and the longest streak of regular-season games with at least 10 points scored -- 1,297 -- in history.
Four takeaways from Nebraska men’s basketball’s NCAA Tournament win over Vanderbilt
OKLAHOMA CITY – Braden Frager. Learn the name.
79 Brilliant Memes That Brought Science And Humor Together
Let’s be honest—complex physics theories and mind-bending math problems can leave most of us staring blankly, wondering what just happened. But one thing most of us can understand is a good meme about them. Somehow, even the most complicated subjects become instantly relatable when they’re turned into a clever joke. And that’s exactly what we’ve got for you today, pandas. We’ve rounded up a bunch of science and math memes that take these “serious” subjects and give them a fun twist. You might no
Sanford Sports launches in Black Hills region
Sanford Sports is expanding into the Black Hills, bringing its research-backed training programs and services to athletes across the region.
Milwaukee stair climb raises awareness for lung health and firefighters
The American Lung Association hosted its 18th annual stair climb in Milwaukee, where participants, including firefighters, climbed 30 stories to raise funds and awareness for lung health.
Four-star forward Joe Philon commits to UCLA
Joe Philon, a four-star power forward in the 2026 class, has committed to UCLA, he told On3. The 6-foot-8 senior out of Montverde Academy (FL) chose the Bruins after considering Ohio State, South Florida, UNLV, and Xavier. Philon, a native of Tampa, Florida, is the No. 56 overall player in the 2026 class, according to […]
My postpartum mental health meant I spent five months on a mother and baby unit
Sofii Lewis was diagnosed with postpartum psychosis tendencies and OCD after giving birth.
Halide co-founder is suing former partner for bringing source code to Apple
Startup drama.