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Worried about rising beef prices? WA farmers say, share a cow

CARNATION, Washington — Far from the refrigerated meat sections of Seattle's grocery stores, two dozen beef cattle relaxed in the afternoon drizzle falling on Carnation Farms' grassy fields. Livestock manager

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Sep 9 • 4:15 AM EDT • Entertainment • thederrick.com
Here is what to do if healthcare costs are eating into your raises

An insurance executive explains how soaring healthcare costs eat into raises, and how workers should discuss alternative options with their company.

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Sep 9 • 4:11 AM EDT • Health • businessinsider.com
Twelve Countries Impose Sanctions on Trade With Israeli Settlements

For the record, Israeli settlements and outposts in the occupied West Bank are considered illegal under international law.

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Sep 9 • 3:57 AM EDT • Politics • politicstoday.org
When will Baleba make his Man Utd debut?

Manchester United made the signing of Carlos Baleba a pretty big deal by parading him onto the pitch before last month's Premier League victory over Ipswich. Man Utd made midfield recruitment a summer priority, so what happens now? On the early evidence, it will be either Kobbie Mainoo or Youri Tielemans, with either Tielemans or Bruno Fernandes in the number 10 role.

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Sep 9 • 3:48 AM EDT • Sports • sports.yahoo.com
Report: Messi plans to buy Spanish second-tier side Eldense

Argentina football great Lionel Messi is set to become majority owner of Spanish second-division club CD Eldense, Spanish sports daily AS reported late on Tuesday. AS said that the 2022 World Cup winner had reached a basic agreement with Colombian investment group TH to take over 100% of the shares.

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Sep 9 • 3:33 AM EDT • Sports • sports.yahoo.com
Entertainment Agency Rep, Journalists in 3 Billion Won Stock Probe

Entertainment Agency Rep, Journalists in 3 Billion Won Stock Probe Authorities probe front-running scheme, 300 stocks, 3 billion won illicit gains

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Sep 9 • 3:20 AM EDT • Entertainment • chosun.com
Down with Politicians! A Reformed Critique of a Bad Idea

Calvin went so far as to characterize the work done by civic officials as a "sacred and noble calling."

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Sep 9 • 3:15 AM EDT • Politics • reformedjournal.com
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🥐 Champions, Ballon d'Or and Sudamericana, Wednesday's 5️⃣ stories

The start of the Champions League has delivered a mixed opening round for Spanish football, while the international spotlight turns to the Ballon d'Or nominations and South America buzzes with the qua...

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Sep 9 • 2:42 AM EDT • Sports • sports.yahoo.com
MidCap Business Credit Closes $10MM Asset-Based Credit Facility for Paper Converter

MidCap Business Credit closed a $10 million asset-based credit facility for a privately held paper converter specializing in custom paper products for

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Sep 9 • 12:58 AM EDT • Business • abfjournal.com
Multiple amiibo Listings Have Apparently Been Spotted On GameStop's Internal Database

New Zelda amiibo were announced yesterday

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Sep 9 • 12:55 AM EDT • Technology • nintendolife.com
Perea Rejoins FGI Risk as Director of Business Development

FGI Worldwide, a provider of working capital financing and trade credit insurance solutions, readded Rick Perea to FGI Risk as director of business

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Sep 9 • 12:50 AM EDT • Business • abfjournal.com
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With AI memes, Trump promotes mythical version of himself as challenges stack up ahead of midterms

President Donald Trump is using memes to portray himself as powerful amid struggles with inflation and international issues.

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Sep 9 • 12:09 AM EDT • Entertainment • seattletimes.com
Nebraska Senator Tanya Storer: Law requires brand committee members’ principal business ‘raising cattle’

Last week, the gubernatorial appointments to the newly restructured Nebraska Brand Committee were announced by the Governor’s Office. Under LB1187, the committee should be comprised of five district representatives plus one representative who owns or...

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Sep 8 • 11:28 PM EDT • Business • tsln.com
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SBA promotes CHOICE Arrangements for small-business health benefits

The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.

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Sep 8 • 9:55 PM EDT • Health • thebusinessjournal.com
SBA promotes CHOICE Arrangements for small-business health benefits

The SBA and CMS are promoting CHOICE Arrangements, formerly known as ICHRAs, as an alternative health benefits model for small businesses.

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Sep 8 • 9:55 PM EDT • Business • thebusinessjournal.com
Man accused of assault, inducing panic at Dr. Amy Acton event pleads not guilty

The armed Ohio man investigators said set off a security scare involving Democratic gubernatorial candidate Dr. Amy Acton pleaded not guilty in court Tuesday.

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Sep 8 • 9:13 PM EDT • Politics • news5cleveland.com
Halo composer Marty O’Donnell takes Nevada race to RNC stage

Nevada congressional candidate and “Halo” composer Marty O’Donnell will speak at the RNC’s Dallas midterm convention as he challenges Rep. Susie Lee.

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Sep 8 • 8:18 PM EDT • Politics • reviewjournal.com
Bernalillo County DA highlights need for accountability and reform in juvenile crime and behavioral health

Bernalillo County District Attorney Sam Bregman addressed crime, juvenile reform and behavioral health during a speech in Albuquerque, emphasizing the importance of accountability and treatment working together.

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Sep 8 • 8:10 PM EDT • Health • koat.com
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Should political candidates have more security?

COLUMBUS, Ohio (WCMH) — The man accused of trying to attack Ohio gubernatorial candidate Dr. Amy Acton appeared in court for the first time Tuesday. Patrick Havas, 38 of Canfield, faces assau…

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Sep 8 • 6:30 PM EDT • Politics • nbc4i.com
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.

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Sep 8 • 6:29 PM EDT • Entertainment • entertainment.substack.com
Activists detained at Oregon State Capitol protesting lithium mine

Activists from Portland, Eugene and southern Oregon were urging Gov. Tina Kotek to step in and stop a controversial lithium mining project.

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Sep 8 • 6:20 PM EDT • Politics • statesmanjournal.com
Midwest Aerial Athletics wins big in Aruba

SIOUX FALLS, S.D. (KELO) —KELOLAND News first took you to Midwest Aerial Athletics back in July. The gym was gearing up to compete on the international stage. “We just competed in Texas, and that was the qualifier for Aruba. So we’re going to Aruba this year and hopefully Australia and then Italy in the next […]

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Sep 8 • 6:10 PM EDT • Sports • sports.yahoo.com
Carlos Augusto: "Never easy playing here, we show character"

Inter leave the Bernabéu defeated in their opening match of the 2026/27 Champions League: despite putting in a great performance and creating a huge number of chances, the Nerazzurri were defeated 2-...

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Sep 8 • 6:04 PM EDT • Sports • sports.yahoo.com
These new resources can help you vet digital mental health tools

Journalists can use guides from professional psychological and psychiatric associations to sort through thousands of mental health apps.

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Sep 8 • 6:00 PM EDT • Health • healthjournalism.org
Detroit businesses face costly repairs after tornado tears through east side
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Sep 8 • 5:59 PM EDT • Business • cbsnews.com
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Aryna Sabalenka Shuts Down Reporter Over U.S. Open Party Question

The World No. 1 pushed back after a reporter described her pre-tournament week as 'lots of parties and fun.'

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Sep 8 • 5:42 PM EDT • Sports • sports.yahoo.com
Raiders' depth chart lists Fernando Mendoza as QB2
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Sep 8 • 5:25 PM EDT • Sports • sports.yahoo.com
Faculty Focus: Chris Erickson, College of Business

Chris Erickson has spent 40 years at NMSU as an economics professor, researcher and mentor. Erickson, a professor in the Department of Economics, Applied Statistics and International Business in...

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Sep 8 • 5:22 PM EDT • Business • newsroom.nmsu.edu
Red Dead Redemption 2 free expansion is a new story set within an alternate timeline

If you need more post-game content, you've found it.

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Sep 8 • 5:00 PM EDT • Technology • gamingbible.com
Driver crashes through Bradenton business on Cortez Road, police say

Bradenton police said the crash happened Sunday afternoon.

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Sep 8 • 4:51 PM EDT • Business • bradenton.com
Colisée’s new owners pledge to ‘bring life back’ to Lewiston’s top entertainment, sports venue

The New York-based owners say the sale signifies a serious future investment in professional hockey in the city, as well as youth hockey, community events and more.

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Sep 8 • 4:44 PM EDT • Entertainment • sunjournal.com
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Jake Gyllenhaal sees a spooky Phoebe Dynevor in first look at M. Night Shyamalan and Nicholas Sparks’ ‘Remain’

Jake Gyllenhaal and Phoebe Dynevor star in the trailer for ‘Remain,’ based on the supernatural romance co-written by M. Night Shyamalan and Nicholas Sparks.

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Sep 8 • 4:37 PM EDT • Entertainment • ew.com
Senate Set to Vote to Begin Debate on Protect College Sports Act

Background The Protect College Sports Act of 2026 (PCSA), introduced in the Senate on June 2, 2026, by Senators Ted Cruz (R-TX) and Maria Cantwell (D-WA) and joined by Senators Eric Schmitt (R-MO) and Chris Coons (D-DE), represents a comprehensive federal legislative effort to reshape the governance and economics of intercollegiate athletics, including redistributing the significant media revenues generated by college sports. Reported favorably 19-9 from the Senate Commerce Committee and placed on Senate Calendar No. 449 on June 24, 2026, the PCSA was substantially revised on August 7, 2026 (Senate Amendment 6768). The PCSA arrives against a backdrop of cascading judicial decisions that have systematically dismantled the National Collegiate Athletic Association’s (NCAA) authority to regulate the economics of college sports.

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Sep 8 • 4:36 PM EDT • Sports • akingump.com
Richarlison Accepts Vasco Offer but Tottenham Loan Limit Blocks Move

Richarlison has reportedly agreed to join Campeonato Brasileiro Série A side Vasco da Gama, but the move can’t proceed because Tottenham Hotspur have already reached their limit for international loans.

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Sep 8 • 4:34 PM EDT • Sports • sports.yahoo.com
Three Rivers Health Department reopens

Three Rivers Health Department reopens after tornado damage earlier this year. (Sept. 8, 2026)

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Sep 8 • 4:07 PM EDT • Health • woodtv.com
Arsenal youngster in international tug-of-war

Ceadach O’Neill’s international future remains unresolved, with Northern Ireland and the Republic of Ireland both still possible options for the Arsenal youngster.Photo by Cameron Smith/Getty Imag...

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Sep 8 • 4:05 PM EDT • Sports • sports.yahoo.com
WBA Foundation cancels 2026 Wisconsin gubernatorial debate

MADISON (WKOW) — The WBA Foundation's televised 2026 gubernatorial debate, originally scheduled for Oct. 9, has been canceled.

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Sep 8 • 4:00 PM EDT • Politics • wxow.com
Mapping the Global Health Landscape: Analysis of Fourteen International Organizations

The global health architecture includes a number of diverse international organizations with different mandates, governance models, financing structures, and operational approaches. This KFF resource looks across a range of variables to provide a descriptive mapping of 14 key global health and related international institutions. It is intended to inform discussions about synergies and coordination, duplication, comparative advantage, shared challenges, and architectural reform.

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Sep 8 • 3:43 PM EDT • Health • kff.org
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Buffalo Bills name 6 captains for 2026 NFL season

Who joins quarterback Josh Allen and linebacker Terrell Bernard as an official captain for the Buffalo Bills in 2026?

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Sep 8 • 3:28 PM EDT • Sports • sports.yahoo.com
Superior Health Foundation awards $271K to 11 UP health initiatives

Among the recipients are the U.P. Health Impact Grant to Upper Great Lakes Family Health Center’s Sawyer Dental Project, four additional U.P. Health Impact Grants and six Equipment Grants addressing behavioral health/SUD, healthy food and wellness, maternal/infant health, accessibility, EMS/first aid and hospice.

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Sep 8 • 2:58 PM EDT • Health • uppermichiganssource.com
Business Aviation Insight. Reassessing Large-Cabin Value After the Falcon 900LX’s Final Delivery Year

Challenger 650 – Photo Credit: Bombardier The Falcon 900LX and Challenger 650 sit at opposite ends of a large-cabin segment that, on 2026 data, now spans nearly $19 million in …

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Sep 8 • 2:49 PM EDT • Business • flightplan.forecastinternational.com
Florida business owner arrested after employees find hidden camera in bathroom: sheriff

NEW SMYRNA BEACH, Fla. (WFLA) — A Florida man was arrested on Monday after it was revealed that he hid a small camera inside an electrical outlet in the bathroom of his business. Donald Hemphill, 5…

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Sep 8 • 2:39 PM EDT • Business • wfla.com
Brentford's rise 'not finished yet'

From starting his coaching journey with MK Dons in 2015, it took the Ireland international 10 years to become a top-flight manager. "I went on a journey to try to be a head coach, but that wasn't straightforward," Andrews told The Football Interview. Playing his junior football in the Dublin District Schoolboy League, second tier Wolves identified Andrews as a target.

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Sep 8 • 2:36 PM EDT • Sports • sports.yahoo.com
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Allegri counts on European 'motivation and adrenaline' for Napoli

Coach Massimiliano Allegri is hoping the arrival of Champions League football can help put Napoli on the right track after back-to-back defeats in Serie A. Victory on the opening day against Genoa has been undermined by successive defeats at the hands of Como and Inter Milan, leaving new boss Allegri looking for a reset when his side welcome Arsenal to Stadio Diego Armando Maradona on Wednesday evening.

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Sep 8 • 2:03 PM EDT • Sports • sports.yahoo.com
Astronaut Health, Lunar and Earth Photography Fill Crew’s Research Schedule

Exploring astronaut health and photographing the Moon and Earth topped the research schedule for the Expedition 75 crew aboard the International Space Station on Tuesday. The orbital residents also kept up life support maintenance following the departure of cargo spacecraft the day before.

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Sep 8 • 1:42 PM EDT • Health • nasa.gov
Ariel Investments names new leadership for private equity unit

The firm named Rodney Cohen co-CEO of Ariel Alternatives alongside Mellody Hobson.

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Sep 8 • 1:32 PM EDT • Business • chicagobusiness.com
Penguins unveil roster for upcoming prospect tournament in Detroit

The Penguins have announced the roster for the team’s upcoming prospect tournament that’s being held in Detroit, starting this weekend. Pittsburgh, along with Columbus, Dallas and Detroit will be participating in a prospect tournament in Detroit with games on Saturday, Sunday and Tuesday. All of the games will be streamed on the Penguins’ website. 27 […]

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Sep 8 • 1:14 PM EDT • Sports • sports.yahoo.com
WBA Foundation cancels 2026 Wisconsin gubernatorial debate

MADISON (WKOW) — The WBA Foundation's televised 2026 gubernatorial debate, originally scheduled for Oct. 9, has been canceled.

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Sep 8 • 12:27 PM EDT • Politics • wkow.com
Atlético v Sobradinho: Crias do Galo are in action today!

Atlético vs. Sobradinho – September 8 (Tuesday) – 3:00 PM🏆 Tournament: 1st round (single match) – Copa do Brasil🏟️ Venue: Arena MRV📺 Broadcast: GaloTV H2bet🗺️ Match Guide: Atlé...

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Sep 8 • 12:25 PM EDT • Sports • sports.yahoo.com
Newman Regional Health, strategic partners now part of brand-new Astra Health collaborative

Already with external partnerships involving University of Kansas Health System and LMH Health, Newman Regiona...

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Sep 8 • 12:13 PM EDT • Health • kvoe.com
Liverpool’s hunt for a new sporting director: Julian Ward and the standout internal options

FSG president Mike Gordon is leading the search for Richard Hughes' replacement, with both internal and external candidates being considered

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Sep 8 • 12:00 PM EDT • Sports • nytimes.com
Fernandes receives second Ballon d'Or nomination

Manchester United and Portugal attacking midfielder Bruno Fernandes has been named in the 30-player shortlist for the 2026 Ballon d'Or. The 32-year-old made 37 appearances across all competitions last season, scoring nine goals and contributing 22 assists, as Manchester United secured Champions League football for 2026-27.

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Sep 8 • 11:56 AM EDT • Sports • sports.yahoo.com
Scientists call for joint efforts to preserve nomadic heritage

At the International Scientific and Practical Conference “Cultural Heritage of the World’s Nomadic Peoples: Preservation, Study, and Development”, scholars and experts from 23 countries urged unified action to safeguard the cultural diversity of nomadic peoples and ensure traditions remain alive for future generations, Qazinform News Agency cites Kabar.

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Sep 8 • 11:41 AM EDT • Science • qazinform.com
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MedStar Washington Hospital Center nurses host community forum on maternal health care cuts, the future of health care in DC

Union registered nurses at MedStar Washington Hospital Center in Washington, D.C. will hold a community forum on Wednesday, Sept. 9, 2026, to discuss the closure of postpartum unit 5F at Washington Hospital Center, the devastating impact of Medicaid cuts in DC, and building a health care system that works for us all.

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Sep 8 • 11:29 AM EDT • Health • nationalnursesunited.org
40-goal Crystal Palace youth striker completes Arsenal transfer

Mylo Bernard has completed his transfer to Arsenal, with the Gunners confirming he’s joining on a scholarship deal with professional terms pre-agreed.Photo via Arsenal.comArsenal have officially ann...

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Sep 8 • 11:05 AM EDT • Sports • sports.yahoo.com
Are Irving, LaVine, Holiday realistic for Heat? And surprising Richards info

The Heat’s challenges in landing one more impactful player. And some notable data on new backup center Nick Richards.

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Sep 8 • 11:01 AM EDT • Sports • miamiherald.com
Wimbledon refusing to credential influencers after US Open drama

Like a Biblical plague that descended upon Egypt, influencers have crashed the US Open tennis tournament in Flushing Meadows this year. The final tennis major of the season has become mostly about everything but the tennis. The US Open invited 100 influencers and content creators, nearly doubling the number invited from last year. Videos are…

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Sep 8 • 11:00 AM EDT • Sports • sports.yahoo.com
In 12 years, Triangle man missed only 1 health insurance payment. He lost coverage

A mistake setting up autopay proved costly for this Morrisville family. Here’s what happened — and how you can avoid it.

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Sep 8 • 11:00 AM EDT • Health • newsobserver.com
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.

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Sep 8 • 10:50 AM EDT • Science • fiercebiotech.com
Ask Pete Dougherty your questions about the Green Bay Packers

Pete Dougherty is taking questions as the Green Bay Packers head into the Week 1 season opener against the Minnesota Vikings in Minneapolis.

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Sep 8 • 10:46 AM EDT • Sports • sports.yahoo.com
Hong Kong students drop in global rankings for maths, science and literacy

City’s students drop out of global 10 in Pisa’s science section – the first time since Hong Kong joined international assessment.

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Sep 8 • 10:42 AM EDT • Science • scmp.com
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Ministry of Science and ICT and NST unveil post-PBS missions for government research institutes by 2026

New mission-oriented R&D roadmap, portfolio, and governance reforms to be finalized and announced within the year

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Sep 8 • 10:30 AM EDT • Science • dongascience.com
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Golf Tournament to Raise Money for Front Porch Housing

Front Porch Housing will bring together approximately 100 golfers, sponsors, and community partners on Monday, Sept. 14, 2026, at Carolina Springs Golf Course for the 2026 Front Porch Housing Golf Classic, an annual fundraiser supporting the...

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Sep 8 • 10:24 AM EDT • Business • greenvillebusinessmag.com
Israel's Problems of Governance: Perennial Causes and Political Context

Essays – The State of Israel is not often associated with the persistent problems of governance that have beset many of its neighbors over the years. With a

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Sep 8 • 10:20 AM EDT • Politics • jstribune.com
Legal complaint against FIFA to cover impact on women’s schedule

A legal complaint against FIFA has been extended to cover its “abusive conduct” towards the women’s game in Europe. The complaint by the European Leagues umbrella group, which includes the Premier League and Scottish Professional Football League (SPFL) as members, was first lodged with the European Commission in October 2024.

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Sep 8 • 9:33 AM EDT • Sports • sports.yahoo.com
Union leaders rally around Kathy Castor after she helps save 700 jobs at Tampa International Airport

'Ensuring the safety and security of the flying public is too important to contract out to the lowest bidder.'

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Sep 8 • 9:26 AM EDT • Politics • floridapolitics.com
The Lewer Agency Inc. BizSpotlight

Discover the latest press releases from The Lewer Agency Inc. with the Kansas City Business Journal's BizSpotlight

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Sep 8 • 9:22 AM EDT • Business • bizjournals.com
Sinclair's Criminally Obsessed to Present "Maternal Mental Health: How the Lindsay Clancy Trial Could Change Treatment" National Town Hall to Air on September 9

BALTIMORE – September 8, 2026 – Sinclair today announced a national town hall examining maternal mental health and the questions surrounding diagnosis, treatment and intervention that have been brought into focus by the Lindsay Clancy trial. Maternal Mental Health: How the Lindsay Clancy Trial Could Change Treatment will stream September 9 across Sinclair’s television station...

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Sep 8 • 9:08 AM EDT • Health • sbgi.net
BSW and AfD – a political love-hate relationship in Germany

The Sahra Wagenknecht Alliance (BSW) could help the Alternative for Germany (AfD) into power in Saxony-Anhalt. It is riddled with infighting

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Sep 8 • 9:07 AM EDT • Politics • dw.com
Television Host and Entertainment Journalist Josh McBride signs with WME and secures exclusive Acast partnership as The McBride Rewind podcast accelerates national growth

The McBride Rewind, the celebrity interview podcast hosted by television personality Josh McBride, has signed with WME for representation in all areas and entered into an exclusive partnership with Acast, expanding the show's reach as it continues to gain momentum in the entertainment podcast space.

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Sep 8 • 9:05 AM EDT • Entertainment • finance.yahoo.com
Six decades of politics (but little government)

The first aired episode of “Star Trek,” entitled “The Man Trap,” premiered on September 8, 1966 — 60 years ago today. I’m actually editing a political science fiction issue of The Forum right now, and it’s prompted to me think a lot about the ways that Trek deals with politics and government and what it’s offered us as commentary. The @smotus report is a reader-supported publication. To support this work, please become a paid subscriber. Subscribe The original TV series ran from 1966 to 1969. It had a loyal but modest following, but the audience grew substantially with the series in syndication for years after that. The franchise developed its first motion picture in 1979, followed by five sequels, and then a whole other series of films built around the “Next Generation” series that first aired in 1987. In recent decades, several more TV series have built up around it, including the current “Strange New Worlds,” now in its fourth season. Throughout the past six decades, the franchise has offered us a good many insights into US politics and international relations, although often disguised as science fiction yarns. The original series was largely a Cold War fable, with the United Federation of Planets (a stand-in for the US) perpetually at odds with the Klingon Empire (a stand-in for the USSR). The “Let That Be Your Last Battlefield” episode (1969) posited a planet divided into two races, largely indistinguishable to outsiders, but nonetheless constituting a brutal racial hierarchy. “Patterns of Force” (1968) showed a struggling planet where the leader had attempted to construct a benevolent dictatorship — literally Nazism without bigotry — and found that authoritarianism could not exist apart from hierarchy and oppression. (Relatedly, I’d put “Star Trek VI: The Undiscovered Country,” high on a list of dad films about the end of the Cold War, near “The Hunt for Red October.”) Get 20% off for 1 year Indeed, the original series itself was something of a political statement, with a multi-racial crew running the Enterprise, a diverse and largely peaceful Federation mostly free from want and oppression, and protected by Starfleet, an armed force whose scientific mission was at least as important as its military one. Famously, when Nichelle Nichols wanted to walk away from the role of Uhura on the original series, none other than Martin Luther King, Jr. met with her and urged her to remain on the show, discussing the importance of viewers seeing an intelligent Black woman as part of the command team three centuries hence. Later series in the Trek franchise offered a good deal of political commentary on their own, but probably none as explicitly and incisively as “Deep Space Nine,” which ran from 1993 to 1999. The episodes surrounding the Dominion War, especially the “In The Pale Moonlight” (1998), showed the compromises, sacrifices, and moral rot associated with winning even a just war — probably better than any series would until “Andor” (2022-25). In “Far Beyond The Stars” (1998), Captain Benjamin Sisko is somehow transplanted to the role of a science fiction writer in 1950s New York. The writer is frequently sidelined and his ideas stolen because publishers don’t want to credit a Black writer. Several series have depicted the secretive Section 31 — an unacknowledged black ops security force operating within Starfleet. These episodes often end up using Section 31 as a foil to show the dangers of a lawless group within a lawful society, even (especially) when that group posits itself as essential for everyone else’s freedom to continue. The current “Strange New Worlds” has played with a few political themes. I found the first two seasons of this show among the best that the Trek franchise has produced in decades, but this season and the last have really been struggling for ideas. Yet one interesting thread is the idea that the diplomatic and enlightened leadership style of Captain Christopher Pike will not work in all situations. “A Quality of Mercy” (2022), which I wrote about here, puts Pike in the middle of a battle with a Romulan vessel in an alternate timeline, and finds that Pike’s conciliatory style would actually make a lengthy and deadly war more likely, while a quick and more violent approach might have prevented the war. This season’s opener, “Valles Marineris,” shows a pre-lightspeed civilization locked in a war to the death with a neighboring planet. The idea of an alliance or a federation hasn’t even occurred to them — their ship’s commander is curious but doesn’t see it as an option. For a franchise as political as “Star Trek,” one thing we almost never see is the government. We get occasional glimpses of Starfleet’s council — mostly uniformed people at a rectangular table — but almost no sense of how the Federation is governed. Are there elections? Who is in the legislature? How much power does the president have? What kind of factional divisions do they wrestle with and how? The shows and films are pretty silent on this. We’ve seen a few military tribunals within Starfleet, but little about how civilians deal with crime and injustice. With recent years seeing some of the franchise’s more interesting plot lines and casts, it seems clear that Star Trek is still full of energy and ideas. Given the erosion of American democracy and the reshuffling of the international order, there’s no shortage of material for future shows to comment on. I’m not sure we should toast to 60 more years, but cheers to a show that continues to teach us about ourselves. Share

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Sep 8 • 9:03 AM EDT • Politics • smotus.substack.com
Andrew Davis Returns to Mission for Inaugural Small Business Expo

Internationally recognized marketing speaker and bestselling author Andrew Davis is returning to Mission to serve as the keynote speaker at the inaugural Mission Small Business Expo, a free, daylong event that connects entrepreneurs with information, resources and opportunities to grow their businesses.

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Sep 8 • 9:03 AM EDT • Business • texasborderbusiness.com
CNN to host California gubernatorial debate ahead of November election

(CNN) — CNN will host a California gubernatorial debate later this month, just weeks before Election Day as voters in the nation’s most populous state decide who will succeed Democratic

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Sep 8 • 9:01 AM EDT • Politics • kten.com
CNN to host California gubernatorial debate ahead of November election

CNN will host a California gubernatorial debate later this month, just weeks before Election Day as voters in the nation’s most populous state decide who will succeed Democratic Gov. Gavin Newsom.

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Sep 8 • 9:01 AM EDT • Politics • cnn.com
China’s Evolving Strategy for International Science and Technology Cooperation

China has been increasing its emphasis on science and technology research as a key priority, including by directly integrating the strategy for international scientific engagement into its broader framework for national power and technological self-reliance.

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Sep 8 • 9:00 AM EDT • Science • quincyinst.org
WSU receives $2.5 million to expand street medicine training

Doctors in WSU’s internal medicine residency program will learn to care for people experiencing homelessness by meeting them where they live in Everett and Spokane.

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Sep 8 • 9:00 AM EDT • Health • news.wsu.edu
Turkish students score above OECD average in science, reading in PISA 2025

Fifteen-year-old students in Turkey scored above the OECD average in science and reading in the latest international assessment, while their mathematics score came within one point of the average, according to results released Tuesday. The OECD’s Programme for International Student Assessment (PISA) 2025 report showed that Turkey earned an average score of 494 in science […]

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Sep 8 • 8:45 AM EDT • Science • turkishminute.com
OPM Names New Health Benefits Chief Ahead of Open Season

There’s new leadership at the Office of Personnel Management’s (OPM) healthcare and insurance division with open season right around the corner and the agency dealing with staff reductions. According to an internal memo obtained by GovExec , Matthew Kiley was hired as associate director of OPM’s h

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Sep 8 • 8:30 AM EDT • Health • fedmanager.com
IPC Systems' Emissions Reduction Targets Validated by the Science Based Targets Initiative

Environmental, Social, and Governance Criteria, Financial Services, GlobeNewswire | NEW YORK, Sept. 08, 2026 (GLOBE NEWSWIRE) -- IPC Systems, In

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Sep 8 • 8:30 AM EDT • Science • macaubusiness.com
Is conservative modernism the way forward for the right?

Anglo-American politics cries out for something better than the demagoguery and AI slop that dominate right-wing discourse. Conservative modernism offers a serious, literate alternative.

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Sep 8 • 8:24 AM EDT • Politics • engelsbergideas.com
Taiwan students rank 4th globally in science, 3rd in reading: PISA 2025

Taiwan's 15-year-old students ranked fourth in the world in science and mathematics and achieved a record-high third place in reading literacy in the 2025 Programme for International Student Assessment (PISA), the Ministry of Education and National Taiwan Normal University (NTNU) announced Tuesday.

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Sep 8 • 8:19 AM EDT • Science • focustaiwan.tw
Trump threatens Canadian jetmaker Bombardier, which has an extensive US footprint

Since Canada-U.S. trade talks collapsed on Aug. 21, the president and his administration have unleashed a barrage of tariffs, threats and personal attacks portraying Canada as weak and dependent.

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Sep 8 • 8:09 AM EDT • Politics • reviewjournal.com
Did California forget about its zero-emission school bus project?

“Considering the state’s requirement for all school buses to be zero-emission by 2035, more sustained statewide support is needed.”

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Sep 8 • 8:00 AM EDT • Health • sacbee.com
Political strategists outline their plan for Senate control and the algorithm cutting vital Medicaid funding

Plus, the NTSB investigators receive flight recorder data from the aircraft that crashed in Miami.

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Sep 8 • 7:19 AM EDT • Politics • nbcnews.com
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NI education: Pupils' scores in reading and maths fall over last decade

The Programme for International Student Assessment (Pisa) tests are seen as a significant benchmark in how education systems are performing.

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Sep 8 • 7:12 AM EDT • Science • bbc.com
Daniel Farke provides fitness update ahead of Chelsea clash

After a quick turnaround following the weekend’s Premier League draw at Brighton & Hove Albion, attentions now turn to the trip to Chelsea for Wednesday’s EFL Cup Round Three tie for Daniel Farke�...

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Sep 8 • 7:04 AM EDT • Sports • sports.yahoo.com
Why executives make bad patients — and how three Triangle leaders say to fix that

Business leaders discuss recovery challenges at Triangle Business Journal panel featuring Chip Payne of Precision Packaging Services and medical experts.

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Sep 8 • 7:04 AM EDT • Business • bizjournals.com
Orient bring in Moldovan midfielder Pascaluta

Leyton Orient sign Moldova Under-21 international Cristian Pascaluta on an initial short-term contract.

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Sep 8 • 7:03 AM EDT • Sports • sports.yahoo.com
Florida Sports Ownership Company Acquires Controlling Interest Of Havoc

On what team owner Keith Jeffries called “an exciting day for the Huntsville Havoc. A new era is dawning for the Huntsville Havoc … but it will be off the ice.

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Sep 8 • 7:00 AM EDT • Business • huntsvillebusinessjournal.com
Louisville tech firm V-Soft already seeing payoffs from its latest acquisition

V-Soft's acquisition of St. Paul-based Logisolve adds data and AI capabilities, helping the Louisville firm expand its technology consulting offerings.

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Sep 8 • 6:42 AM EDT • Business • bizjournals.com
💣 James Rodríguez is close to joining Italy's second division!

The former Real Madrid player is close to Serie B: Avellino are betting on the attacking midfielder’s international experience in their push for promotionJames Rodríguez’s future could lie in Ita...

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Sep 8 • 6:17 AM EDT • Sports • sports.yahoo.com
Parkland study could change how hospitals treat a leading cause of maternal, infant mortality

A Parkland Health study could help address a common but life-threatening pregnancy complication. Researchers found universally prescribed aspirin led to a significant decrease in severe preeclampsia — one of the leading causes of infant and maternal mortality in the U.S. and globally.

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Sep 8 • 6:02 AM EDT • Health • keranews.org
Milwaukee Wheelchair lacrosse team looks ahead to nationals

The Milwaukee Eagles partner with Marquette University's men's lacrosse team.

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Sep 8 • 6:01 AM EDT • Sports • sports.yahoo.com
A new development map of north St. Louis identifies $337 million worth of housing, business projects

Officials say a new development map will help the city as it plots development efforts in north St. Louis areas impacted by last year’s tornado.

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Sep 8 • 6:00 AM EDT • Business • stlpr.org
Filipe Luís confirms Monaco’s continued Erik Lira pursuit

AS Monaco manager Filipe Luís has said that he will “continue to want Erik Lira in every transfer window”. It comes after the Principality club missed out on the Mexico international this summer....

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Sep 8 • 6:00 AM EDT • Sports • sports.yahoo.com
Steve Kornacki on a tightening Senate primary in New Hampshire

The open seat is a top target for national Republicans in November, though Democrats are currently favored.

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Sep 8 • 6:00 AM EDT • Politics • nbcnews.com
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Real Madrid vs Inter Milan – Predicted lineup and team news

Real Madrid begin their UEFA Champions League journey this Tuesday with a high-profile showdown against Italy’s titleholders, Inter Milan, at the iconic Estadio Bernabéu.Los Blancos arrived into th...

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Sep 8 • 5:45 AM EDT • Sports • sports.yahoo.com
New German health, transport ministers sworn in six weeks late

Germany's new health and transport ministers were sworn in on Tuesday before the Bundestag, the country's lower house of parliament, six weeks after their appointment. Carsten Linnemann and Steffen Bi...

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Sep 8 • 5:33 AM EDT • Health • yahoo.com
Richarlison running out of options for Tottenham exit

Tottenham and forward Richarlison are running out of options for an amicable conclusion to a messy transfer saga. Richarlison started Spurs’ opening-day loss at Brentford on August 22, but was left out of the club’s 25-man Premier League squad list named by Roberto De Zerbi on Thursday.

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Sep 8 • 5:33 AM EDT • Sports • sports.yahoo.com
5 Android phones you should buy instead of the Samsung Galaxy S26 FE

Thinking about picking up the new Galaxy S26 FE? Before you do, you might want to consider your alternatives.

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Sep 8 • 5:30 AM EDT • Technology • androidauthority.com