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Steelers sign another cornerback
The Steelers are thin at cornerback right now with the Joey Porter Jr. trade and Jamel Dean dealing with an ankle injury.
Falcons Offense Explodes To 40.0 Points With Penix Back
Michael Penix Jr. returns to lead the NFL's best offense. See the shocking stats, the 45-24 win, and why the Falcons are suddenly scary.
Jazz Chisholm Jr. Has Surprising Response After Costly Yankees Error
The New York Yankees are staring at another postseason deficit, and the way they got there feels painfully familiar. New York committed three errors against the first four batters in the bottom of the first inning Monday night in Game 2 of the American League Division Series, immediately putting itself in trouble. And one of…
US appeals court weighs block on Kennedy's vaccine panel appointments
A lawyer for the Trump administration told a federal appeals court on Tuesday that a judge had improperly hamstrung an influential vaccine advisory panel by blocking Health Secretary Robert F. Kennedy Jr.'s handpicked appointees from serving on it.
RFK Jr.'s embrace of AI confounds some MAHA allies and medical experts
Health Secretary Robert F. Kennedy Jr.’s unexpected embrace of artificial intelligence has rankled some of his allies in the “Make America Healthy Again” movement
The Harvard Crimson (@theharvardcrimson)
83 likes, 0 comments - theharvardcrimson on October 6, 2026: "Harvard’s Faculty of Arts and Sciences is launching 25 tenure-track faculty searches, FAS Dean Hopi E. Hoekstra announced in a Monday email to faculty, further loosening a University-wide hiring freeze instituted last spring as the school draws an influx of philanthropic support. The searches, which include positions across the FAS’ three divisions and the School of Engineering and Applied Sciences, come less than a week after Hoekstra announced the school would also be upping Ph.D. admissions for the upcoming admissions cycle — and as the University continues soliciting support from donors for its academic programming. Full story linked in bio. 🖋: Abigail S. Gerstein and Amann S. Mahajan 📷: Mae T. Weir".
Commanders Practice Squad RB Signs With Another NFL Team
The Washington Commanders will have a vacancy to fill on the practice squad after Robert Henry Jr. signed elsewhere on Monday
Former Cocoa Beach classmates are now Orlando Health doctors. Photos
Former classmates from Cocoa Beach Jr./Sr. High, Dr. Anita Fazeli and Dr. Srividya Kannan will share an Orlando Heath location in Viera.
A-State names Dr. William McLean provost, vice chancellor
Dr. William McLean has been named the Arkansas State University provost and executive vice chancellor, said Chancellor Dr. Calvin White Jr. McLean, a two-time graduate of A-State and longtime faculty...
United Talent Agency signs Kansas City Chiefs’ Foolish Club Studios
United Talent Agency signs Kansas City Chiefs’ Foolish Club Studios | @EdEastonJr
Rob Gronkowski on Patrick Mahomes' performance post-knee surgery
During his interview with @EdEastonJr, FOX Sports analyst Rob Gronkowski discussed Kansas City Chiefs QB Patrick Mahomes' performance post-surgery
Minnesota gubernatorial candidates discuss business platforms at Economic Club discussion
Minnesota gubernatorial candidates Sen. Amy Klobuchar (DFL) and Rep. Lisa Demuth (R) faced off Monday afternoon in a forum hosted by the Economic Club of Minnesota. Each candidate took the stage independently to answer questions from a moderator for 30 minutes apiece.
GOP is at risk of significant state legislative losses, Post analysis finds
Democrats have a rare chance to boost their state presences after years of Republican gains.
Critical Atlassian Flaw Lets Unauthenticated Attackers Read Known Files Across 8 Products
Atlassian fixes a critical path traversal in 8 Data Center products that lets unauthenticated attackers read files if exact paths are known.
Robert Henry Jr. heads to Seattle
The Seattle Seahawks signed running back Robert Henry Jr. off of the practice squad of the Washington Commanders on Monday
RFK Jr. moves to reveal health care costs
HHS Secretary Robert F. Kennedy Jr. announced a new initiative requiring the health care industry to publish clear pricing data for consumers.
Paris Johnson Jr. to miss rest of season
Cardinals OT Paris Johnson Jr. will miss rest of 2026 because of injury
Jeremy Fears Jr. Voted Big Ten’s Preseason Best
Michigan landed two guards on the preseason All-Big Ten team, and Jeremy Fears Jr. had the last word. #GoGreen
Why I Don’t Think Ride Or Die Should Have Been Cancelled (And What Company Should Save It...)
(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) So…I recently came across a Reddit thread, talking about films on streaming, wondering why there are no reliable sources out there for streaming ratings data. Sigh. Honestly, as annoyed as I am that so many still don’t realize that we have streaming ratings, I somewhat get it. Until now, there was such a long delay between when a show or film came to streaming and when we got its viewership data; I understand why people were confused. (But, as you know, this just changed.) Also, even back in the day, how many people knew how well films did on television? Luckily, as a reader, you’re in the know. Okay, on to this week’s issue. I want to take a look at Prime Video cancelling Ride or Die and whether I agree with that decision. Overall, we didn’t have any breakout hits (no TV shows landed over 20 million hours according to Nielsen) but we have a lot of steady performers on the streaming charts. Plus, we’ll look at where $50 million in missing box office dollars went. (Spoiler: straight-to-streaming.) All that, plus new episodes of The Secret Lives of Mormon Wives, Supergirl heads to streaming, a new YA show does well on Netflix, the viewership for the Daily Wire’s $50 million fantasy show, what TV show hit-maker can’t make streaming hits, CD sales, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of September 7th to September 13th, 2026. You can find a link to my terminology here.) Subscribe Television - Ride or Die Is a Hit…But It Got Cancelled? What The Data “Says” I hate the phrase “here’s what the data says”, even though sometimes I find myself using it. If data just told us everything, we data folks would be out of a job! Data is often messy, complicated and nuanced. When it comes to strategy, many of the best decisions can’t actually use “data”, since it’s vastly too complicated to model. Anyways, I’ve been singing the praises of Prime Video’s Ride Or Die this summer, a show that did very well for them. And yet…it got cancelled. Now, usually when a show gets cancelled, a bunch of websites say “a hit show got cancelled”... Here’s the thing, though: in this case, they’re right! The data “says” that this show was a hit. Specifically, out of 522 first seasons to make a week on the Nielsen charts since 2020, it’s the 75th biggest. On Amazon, Ride or Die is eighth out of 41 first seasons: That’s top 15th percentile all time, almost exactly, which is my definition of a “hit”! I mean, outside of Reacher, Amazon needed a hit this summer! (Admittedly, Off Campus did well for Amazon in the spring, but Ride or Die performed even better.) So what happened? Why did Amazon cancel one of their rare 2026 bright spots? Well, Deadline reported a reason—which I’ll get to—but I’d break it down into three relevant questions: What is a given streamer’s reasoning? Is that reasoning sound? Could the stated reason not be the real reason? According to Deadline, Amazon felt the show “over-indexed” in middle-aged women. (This was based on leaks from within Amazon.) The logic is this: Amazon already reaches this demographic because of unlimited two-day shipping bundled with Prime, so they don’t really need more shows like this. Now, it’s my job to ask if that’s a good reason, and I’ll be honest, in this case, I don’t think it is. Sure, this show may “over-index” in middle-aged women—I’ll just assume that’s the case here—but I think folks often oversell how important over-indexing actually is. When a show is a “hit”, it isn’t a bit bigger than its rivals; it’s usually multiples bigger. For example, Elle only made the charts for two weeks at 8.3 million hours each. So Ride or Die was 80% bigger in its first two weeks, and likely had a much stronger hold, with its terrific 13 million hours in week three. Ride or Die was nearly three times bigger than Sterling Point through three weeks too. And that means that _Elle, Sterling Point a_nd other Amazon YA shows need to not just over-index a little with younger women (assuming that’s who Amazon prefers over middle-aged women), but massively over-index. Otherwise, more people in that demo (and a bunch more besides) likely watched Ride or Die. (I’ll try to explore this concept more in a future article.) And don’t get me started on how Ride or Die did compared to a certain (very, very popular, possibly the world’s most popular) YouTuber’s reality show…which didn’t make the charts after its first week and likely cost much, much more than Ride or Die. All to say, Amazon-MGM Studios/Prime Video can tell reporters that this show didn’t reach the right audience, but that excuse feels weak to me. So this leads to the third question: could other reasons have come into play? Yes! Renewal or cancellation decisions rarely (I’m tempted to say “never”) boil down to one variable. At its simplest, it’s two things: budget versus viewership. But often factors like critical acclaim, ownership and, yes, personal opinion come into play. In this case, Amazon has a new executive running things, and this show isn’t owned by Amazon-MGM Studios (unlike Elle). And yes, it may not have indexed with the right target viewers, too. Likely all of those factors came into play.1 My guess is ownership ended up mattering most. Amazon doesn’t own Ride or Die. It’s actually produced by another major studio. Fortunately/allegedly, this show is being shopped around. I can think of one brand new CEO who should consider it for one of his two major streamers…especially if he wants to rebuild goodwill in Hollywood. His name is on this list of exec producers of Ride or Die… If David Ellison needs some goodwill—and he does—rescue this female-led show tomorrow and grab some good headlines for a day. The data justifies it. Quick Notes on TV We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… How The Secret Lives of Mormon Wives latest season did on Hulu, post-controversy... Whether Supergirl soared on HBO Max... Why the box office is losing money due to the streamers... The viewership for the Daily Wire’s $50 million fantasy show... Updates on The Gentlemen, Lanterns, Outer Banks, King of the Hill and more... What former hit-maker has three streaming flops in a row... Whether The Mandalorian and Grogu popped in week two... All the flops, bombs and misses... And a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue. Coming Soon! Oh man, we’re almost caught up! We just have two more issues, then the streaming Ratings Report will be coming out just two weeks after a TV show premieres! Next issue, I’ll be looking at the first two weeks of the NFL Thursday night games on streaming, a huge new spinoff, Reacher’s Neagly on Prime Video, and the latest edition of Monster: The Lizzie Borden Story on Netflix, the return of Slow Horses on Apple and MobLand (quietly one of their biggest shows) on Paramount+, and Dancing with the Stars on both ABC and Disney+. Plus I’ll take a look at animation for adults in 2026. The week after, a ton of movies are coming to streaming: Toy Story 5 on Disney+, Backrooms on HBO Max, Jackass: Best and Last on Paramount+ and The Breadwinner on Netflix, plus a Unabomber film on Netflix and a romcom on Prime Video. Woody Harrelson and Matthew McConaughey have a show on Apple, along with a game show inspired by Willy Wonka that everyone seems to hate. Long term, some crazy (but hopefully crazy like a fox) IP news. FX ordered a new Sons of Anarchy show from Charlie Hunnam, but it’s not about the biker gang. No, it features the show’s cast playing themselves in a new “meta-thriller”. Huh. And a lot of the cast is coming back. Next, Ryan Gosling is producing a Flintstones movie about a “grown-up Bamm-Bamm Rubble”. Also, huh. This one is in “early development” so we’ll see what happens. Both projects are based on IP, but also seem to have crazy takes on the IP, which I like.
Sen. Tillis says his vote for Hegseth was 'biggest regret of my career' in new book
Republican Sen. Thom Tillis says in a new book that his deciding vote to confirm Defense Secretary Pete Hegseth in January 2025 is the “biggest regret of my career” and that he also “should’ve stopped” Robert F. Kennedy Jr. from becoming Health and Human Services secretary in the early days of President Donald Trump’s second term.
Former Angels Scout Bobby Fontaine Jr. Dies at 73
The Los Angeles Angels announced former scouting director Bobby Fontaine Jr., who served the team for more than a decade, died aged 73. The post Former Angels Scout Bobby Fontaine Jr. Dies at 73 appeared first on LA Sports Report.
‘The Batman Part II’ halts production as director Matt Reeves steps away for personal reasons
After years of delays, ‘The Batman Part II’ has ‘temporarily paused’ production as director Matt Reeves ‘focuses on a family matter.’
Trump administration finalizes transparent healthcare pricing rules
The rules are intended to make healthcare pricing information more accurate, standardized and easy to use
NAMI Central Florida highlights mental health resources during Mental Illness Awareness Week
Freddy Morello Jr., CEO of NAMI Central Florida, discusses free resources, new programs, and an upcoming gala during Mental Illness Awareness Week.
Lions Injury Could Force Brad Holmes Back Into Trade Market
Rock Ya-Sin’s hamstring injury could increase the Detroit Lions’ urgency to trade for a cornerback after their pursuit of Joey Porter Jr.
Watch live: RFK Jr., Trump officials unveil health care price transparency push
Health and Human Services Secretary Robert F. Kennedy Jr. and Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz will announce new efforts Monday aimed at strengthening health c…
Patrick Mahomes shares an emotional message for an injured teammate
During his press conference, Kansas City Chiefs quarterback Patrick Mahomes shared an emotional message for injured WR Tyquan Thornton | @EdEastonJr
The Daily Mauling: 10/5/26
Kansas Jayhawks News It’s official, Melvin Council, Jr is coming back to Kansas Jalon Daniels got his first NFL start this weekend. It didn’t go especially well, but he vows to use the lessons he learned moving forward What did we learn from the 55-0 drubbing of MTSU? The LJW weighs in The Topeka Capitol-Journal […]
Yale School of Medicine On the Science of Childhood Anxiety, Say, Anxiety Disorders Are the Most Common Mental Health Challenges In Youth
Credit: Matt Bradbury October 5, 2026 - By Isabella Backman - Anxiety disorders are the most common mental health challenges in youth. Left untreated, they can disrupt the lives of both children and their families. The good news is that with intervention, most children will overcome these conditions. Across Yale School of Medicine, scientists are working to understand anxiety at every level, from common anxious behaviors to molecular biomarkers in the brain. They are using their findings to develop and disseminate new evidence-based treatments for childhood anxiety. Today, the go-to treatment for childhood anxiety disorders is cognitive behavioral therapy (CBT). This is a form of psychotherapy that teaches children skills for confronting anxious thoughts and helps them practice managing situations that cause anxiety. While it is the gold-standard treatment backed by considerable scientific evidence, up to 50% of children will not see sufficient benefit from CBT alone. Wendy Silverman, PhD, Alfred A. Messer Professor in the Child Study Center, co-directs the Anxiety and Mood Disorders Program alongside Eli Lebowitz, PhD, associate professor in the Child Study Center. One of their main interests is learning how to improve outcomes beyond CBT. “We’re developing cutting-edge, research-based knowledge that can reduce the suffering that anxiety causes children and their families,” says Silverman. Changing parent behavior YSM experts are investigating how to improve CBT outcomes for children by involving the parents. Silverman’s research has uncovered two main components of parent intervention that improve childhood anxiety: not enabling children to completely avoid the things that make them anxious and taking steps to enhance their autonomy. Parents may unintentionally reinforce their child’s anxiety by allowing them to avoid what makes them anxious. They also may unintentionally limit the children’s sense of autonomy by being overly intrusive. “One of the things that we take pride in is that we’ve focused on trying to understand what parents need to do, and to test our ideas and see if changing the parents’ behaviors is enhancing the effects of CBT,” Silverman says. “Our findings thus far suggest that they do." As much as CBT can be helpful, it can also be challenging to get one’s child to do the necessary steps for CBT to work. This is one important reason why Lebowitz created a novel intervention program for parents named Supportive Parenting for Anxious Childhood Emotions (SPACE). Existing intervention programs often teach parents to act as therapists for their child, such as training them on how to practice breathing exercises. “It makes sense, but this doesn’t work very well in practice,” says Lebowitz. “And part of the reason, I think, is that it’s not easy to get your kid to do things, especially if they’re not excited about doing it.” SPACE is unique because it focuses entirely on parent involvement and changing parental behavior—children are not involved in the sessions. For example, parents learn how to use supportive messages that convey confidence that their child can tolerate and manage distress. “It might sound like a parent saying to a child, ‘I get that this is really hard for you, but I know that you can handle it,’” Lebowitz says. The program also works with parents to identify the ways in which they are accommodating anxious behaviors. “We’ll pick one thing that parents are doing that is an accommodation and help them make a detailed plan for how they’re going to change that,” Lebowitz explains. Treating Anxiety in Children and Adolescents Much of the existing research on SPACE has focused on parents of children under age 14. Ongoing studies are now exploring its use with parents of older teens. “Both anxiety and accommodation can interfere with normative developmental shifts during the teen years, including increased autonomy and individuation from parents,” says Rebecca Etkin, PhD, associate research scientist in the Child Study Center. “In this sense, SPACE may be particularly well-suited for anxious teens and their parents. We want to see whether it is effective during this distinct developmental window.” Unfortunately, many families in need of CBT face barriers, including limited availability of services and geographic constraints. One way to improve access is digital interventions. Silverman and her team are developing an evidence-based digitized intervention program for parents that they can access directly from their computer or smart phone. “The work we’re doing will be one of the very few parent interventions that is digitized and importantly tested for effectiveness,” she says. Creating interventions for anxiety-related challenges Silverman and Lebowitz recently received a generous gift to develop and test other interventions that help parents reduce other child anxiety-related behavioral and emotional difficulties, such as restrictive eating and unexplained somatic symptoms. One of these projects in particular focuses on understanding the risks of social media and its potential benefits, including offering a sense of connection. “A lot of research has focused on the idea that social media is harmful and the less of it the better,” says Lebowitz. “But we actually see is that this is not quite right—there are negatives, but there are also positives. So, we’re trying to get a little bit more nuanced of a picture.” The team is working with teens with social anxiety and their parents over an extended period to better understand their social media habits and how their anxiety levels affect engagement with different platforms. The teens will answer questions sent to an app on their phones about mood and social media usage in an effort to capture emotional responses as they unfold. “We hope to develop interventions that can help make the best of social media while protecting against the more problematic effects,” Lebowitz says. The brain’s role in anxiety Researchers are also testing therapies to address anxiety at the neurological and molecular levels. In collaboration with Dylan Gee, PhD, professor of psychology in Yale's Faculty of Arts and Sciences, and Hilary Blumberg, MD, John and Hope Furth Professor of Psychiatric Neuroscience at Yale School of Medicine, Lebowitz and Silverman are using brain imaging to identify changes in a child’s brain before and after parents enroll in SPACE. In one study, children viewed anxiety-inducing images while undergoing magnetic resonance imaging (MRI); the researchers conducted scans with and without the children’s parents nearby. Before SPACE, children’s brains were better able to activate the regulatory circuitry needed to turn off an anxious response when their parents were nearby. But after SPACE, children could activate this circuitry even without the parent around. “As parents work on gradually reducing some of their accommodations, you can see a child get better at regulating their own fear system in the brain,” Lebowitz says. “It’s remarkable.” Research into the molecular underpinnings of anxiety can also inform new childhood anxiety treatments. In a recent study, Lebowitz, Silverman, and Flora Vaccarino, MD, Harris Professor in the Child Study Center, discovered that a protein known as fibroblast growth factor 2 (FGF2) could be protective from the toxic effects of stress. FGF2 levels in children and their parents were linked to the children’s risk of developing anxiety and depression, the study showed. The findings could help explain why some children who are exposed to early life trauma such as poverty or abuse are more prone to developing mental health disorders. And FGF2 could be a target for treatment. “This is very novel because it starts to give a clue to what is the molecular chain that connects those lived experiences to the actual psychological outcomes,” Lebowitz says. New ways to study and treat childhood anxiety Michael Crowley, PhD, associate professor in the Child Study Center, collaborates with Silverman and Lebowitz to study the role that attention plays in development and maintenance of childhood anxiety. There is a large body of research that shows that anxious children, like anxious adults, are prone to focus on threatening stimuli such as angry faces compared with neutral faces. This has led to innovative interventions that involve attention retraining. The idea is that if experts train children to look away from threatening stimuli, it may reduce their anxiety—especially children with social anxiety who are most prone to attend to threats. The researchers have just completed a clinical trial for attention retraining with 10- to 14-year-olds with social anxiety disorders and are currently analyzing the findings. Besides this innovative attention retraining research, as Crowly notes, “I like to design tasks that are engaging to kids,” Crowley says. “My goal is to assess something without the kids knowing what we are assessing.” With this goal in mind, Crowley has created a virtual game, named Boom, to study threat processing in children with anxiety disorders. The game is similar to that of hot potato—the child and three digital players take turns virtually passing a ball to each other’s gloves. At some point, the ball turns into a bomb, and as the bomb lands in each player’s glove, the outline of the glove turns yellow. The goal is to avoid having the bomb go off in your glove. What isn’t obvious is that the game is designed to measure different types of threatening stimuli, both ambiguous and direct. In the game, the direct threat occurs as the bomb is traveling towards your glove. The ambiguous threat is the yellow outlined glove as it is unknown where the bomb will travel next. While children play the game, Crowley’s team measures their brain activity using electroencephalography (EEG). The researchers have discovered that in kids with anxiety, the brain reacts more strongly to ambiguous threats than it does in their peers, but less strongly to direct threats. They believe that the initial abnormally large brain response to not knowing where the bomb is going impairs the brain's ability to properly respond when the threat is actually traveling the child’s way. “The brains of children with anxiety are unable to differentiate between threats you need to do something about and those that are not your problem.” Michael Crowley, PhD, develops innovative games for studying anxiety in children and adolescents.Credit: Matt Bradbury Based on these insights, Crowley hopes to study whether interventions like attention training could restore appropriate threat processing. Crowley’s team is also working on a test called the Balloon Risk Avoidance Task, which evaluates risk-taking and avoidance behaviors. It features a digital balloon that is full of air and about to burst. Kids have six seconds to let air out of the balloon. The more air they let out, the less risk they face that the balloon will pop. But at the same time, the balloon becomes less valuable as it deflates. “The more air you keep in the balloon, the more points you get,” Crowley explains. So far, the researchers have found that when the balloons pop unexpectedly, teens with social anxiety show distinct brain responses. Studying these responses can help psychologists understand the underlying pathways driving the various manifestations of anxiety. The genetics of anxiety When Thomas Fernandez, MD, associate professor in the Child Study Center and of psychiatry, was still in training, there was a lot of excitement about understanding the genetics associated with autism spectrum disorder. Since then, scientists have identified around 250 genes associated with autism. The genetic contribution to anxiety disorders, on the other hand, has historically received less attention. Anxiety is less heritable than autism, but the genetic contribution for anxiety disorders that emerge in childhood may be higher than for anxiety disorders overall. While scientists estimate the heritability of anxiety disorders in general to be around 30% to 50%, some studies suggest higher heritability for certain childhood-onset anxiety presentations. “I saw firsthand how researchers in the field went about finding vulnerability genes for autism,” Fernandez says. “So, we’re using a very similar playbook for childhood anxiety.” “I saw firsthand how researchers in the field went about finding vulnerability genes for autism. So, we’re using a very similar playbook for childhood anxiety.” Thomas Fernandez, MD Associate Professor In the Child Study Center and in Psychiatry Now, Fernandez and Emily Olfson, MD, PhD, assistant professor in the Child Study Center, are studying children and their parents to identify genetic changes that are present in the child but not the parents, known as “de novo mutations.” “All of us have some de novo mutations—maybe about 50 to 100 sprinkled throughout the genome,” Olfson says. “But when they occur within the coding regions of genes, they can be really disruptive.” Previous research shows that people with autism have higher rates of damaging de novo mutations than the general population. In 2022, Olfson, Lebowitz, Silverman, and Fernandez published a study on 68 children and their families that found that children with anxiety had similarly high levels of these mutations. Studying de novo mutations can help point the researchers to where they should be looking for genes associated with anxiety. “The end game is using the genes to steer us toward the right part of biology that we can then target to come up with better treatments,” Fernandez says. Building on those findings, the team is now studying more families to better understand how these de novo mutations, along with other genetic and environmental factors, shape pediatric anxiety disorders. They recently received a National Institutes of Health grant to enroll 750 new families over the next five years. Olfson is the principal investigator, with co-investigators Lebowitz, Fernandez, Silverman, and Shuangge Steven Ma, PhD, department chair and professor of biostatistics at Yale School of Public Health. Neurodevelopment, Risk Genes, and Mental Health Conditions - The Olfson Lab Joel Gelernter, MD, Foundations Fund Professor of Psychiatry, is interested in how different anxiety disorders differ genomically. “We are studying social phobia, panic disorder, and generalized anxiety disorder, working to understand why people differ in their risk to these specific anxiety disorders and evaluating various risk factors,” he says. Gelernter was recently involved in one of the largest studies to date of the genomics underlying anxiety disorder. The study included around 122,000 people with anxiety disorders and around 730,000 without. It found that some genetic differences associated with anxiety were linked to signaling that helps reduce overactivity in the nervous system. Many anxiety medications available today work by targeting this process. “It’s nice when the biology that you get out of a large genome-wide study ratifies things that we already know because that can help increase confidence in further findings from the study,” Gelernter says. Uncovering the neurobiology of psychiatric disorders John Krystal, MD, Robert L. McNeil, Jr. Professor of Translational Research and chair of the Department of Psychiatry, is interested in the neurobiology of psychiatric disorders, including post-traumatic stress disorder (PTSD), of which anxiety is a major symptom. In the late 1980s, Krystal’s team discovered that the drug yohimbine activated symptoms in patients with PTSD. “This was the first time we could link a specific biological mechanism to the symptoms of PTSD,” Krystal says. At the time, he adds, this finding was highly controversial. “A lot of people felt that PTSD was a purely psychological syndrome that didn’t have an underlying biology.” Since then, Krystal has dived deep into understanding the neurobiology of PTSD to learn how to better treat it. His team is evaluating the use of ketamine and psychedelics. These would be among the first treatments to be developed specifically for PTSD. They may also be applicable for other disorders including anxiety disorders, Krystal adds. An important gap in PTSD treatment is the absence of biological tests that inform how to best help patients manage their PTSD symptoms. A doctor doesn’t diagnose cancer based on how they feel. Rather, they use tests of the biology of the cancer to determine the best course of treatment. “And we can’t do that in any psychiatric disorder other than Alzheimer’s disease,” Krystal says. “But now we are building a foundation for this approach to the treatment of anxiety disorders for the first time.” Source: Yale School of Medicine
Engelbert Humperdinck says he ‘went through hell’ rejecting 'casting couch' advances early in career
Taylor Farms and Mexico’s Health Ministry Now Make the Same Cyclospora Argument. The Produce Industry’s Own Association, FDA and CDC Rejected It in September. Here Is a Specific Request to Eight People Before the Industry Meets in Orlando.
I spent four hours Sunday morning taking the deposition of an expert retained by the defense in the E. coli O157:H7 outbreak of November 2024 – the one
Brian Thomas Jr. reaches end zone in Week 4
Jaguars WR Brian Thomas Jr. held to 17 yards but post receiving TD
Marvin Harrison Jr. scores TD in Week 4
Arizona Cardinals wide receiver Marvin Harrison Jr. posted a single 12-yard reception for touchdown on four targets in Week 4
Melvin Council Jr. Announces His Return to Kansas
Melvin Council Jr. Announces His Return to Kansas
AkzoNobel to sell unit to Nippon Paint for over $1 billion, FT reports
Dulux paint maker AkzoNobel is nearing a deal to sell its Southeast Asian decorative paints business to Nippon Paint for well over $1 billion, the Financial Times reported on Sunday, citing people familiar with the matter.
Deron Rippey Jr., transfers shine during Countdown to Craziness
A handful of new Duke players, including Deron Rippey Jr. and John Blackwell, shined during the 'Countdown to Craziness' scrimmage.
Falcons RB Bijan Robinson opens up about new acting experiences
During his interview with @EdEastonJr, Atlanta Falcons running back Bijan Robinson opened up about new acting experiences
Blue Jays Handed Clear Offseason Message on Pirates’ Oneil Cruz
After reaching the World Series last year, the Toronto Blue Jays failed to reach the postseason this year. As a result, the Blue Jays’ front office will need to bolster the team if it wants to return to the Fall Classic. Vladimir Guerrero Jr. had an awful 2026 season by his standards, hitting .260 while […] The post Blue Jays Handed Clear Offseason Message on Pirates’ Oneil Cruz appeared first on HEAVY.
CSU defensive coordinator walks out during blowout loss
CSU coach Jim Mora Jr. stripped defensive coordinator Tyson Summers of play-calling duties after Oregon State scored on its first two drives, prompting Summers to leave the sideline entirely during the 56-26 loss.
Seattle signs Velus Jones Jr.
Seattle Seahawks RB Velus Jones Jr. signed to main roster
Raiders Should Consider Trading For This Scuffling Receiver
The Las Vegas Raiders need a receiver, and Marvin Harrison Jr. is struggling with Arizona.
How would you grade the Steelers’ Joey Porter Jr. trade?
Steelers news and notes for Saturday, Oct. 3.
HHS cuts minority health budget for RFK Jr.’s security
HHS cut $12 million from its Office of Minority Health as Secretary Robert F. Kennedy Jr.’s security costs rose, prompting criticism from congressional caucus l...
Turnover issues, Jalen Washington highlight Tennessee basketball scrimmage
Jalen Washington, Manny Green and Terrence Hill Jr. were stars of Tennessee basketball's open scrimmage on Oct. 3 at Food City Center.
Carlos Washington Jr. signed to 53-man roster
Dolphins RB Carlos Washington Jr. goes from the practice squad to 53-man roster
Issey Miyake and Givenchy: Art and Science
Satoshi Kondo and Sarah Burton show us why they’re BoF500 cover stars.
Joey Porter Jr. not on injury report
Joey Porter Jr. expected to make Cowboys debut in Week 4
Trey Smith on his blocking approach to accommodate running backs
During Friday's press conference, Kansas City Chiefs OL Trey Smith addressed his blocking approach to accommodate running backs | @EdEastonJr
Saints vs. Falcons: QB to QB Matchup
Tyler Shough will face off against Michael Penix Jr. in game to determine the leader of the division
Dave Toub comments on possible efficiency concerns for Harrison Butker
During his press conference, Kansas City Chiefs coordinator Dave Toub addressed possible concerns about kicker Harrison Butker | @EdEastonJr
Massive Entertainment: The Next Chapter Begins
Ubisoft’s Creative House 2 is named Massive Entertainment, becoming the global label for Tom Clancy's The Division, Ghost Recon, Splinter Cell, alongside new original IP including March of Giants.
Chris Godwin Jr. expected to play in Week 4
Buccaneers WR Chris Godwin Jr. on track to play after two full practices
Pacers Coach Rick Carlisle Strongly Praises Newcomer Kelly Oubre Jr.
Indiana Pacers head coach Rick Carlisle praised new small forward Kelly Oubre Jr.
Jaren Jackson Jr. Knows What Comes After a Jazz Breakthrough
Memphis star Jaren Jackson Jr. warns a rising Utah core that sustained success demands an even-keeled temperament as the pressure of expectations replaces the freedom of rebuilding.
Kings' Projected Starting Five Ranked No. 29 in NBA
The Sacramento Kings' quiet offseason has most projections placing the franchise towards the bottom of the Western Conference. But, the team should definitely see improvements with the addition of Darius Acuff Jr. and key players returning to health.
GOP super PAC pauses spending in North Carolina Senate race, shifting money to Kansas
The new moves from the Senate Leadership Fund reflect a difficult landscape for Republicans, with increasingly competitive races in red states.
A Delaware County estate with a par-three golf hole and an entertaining space is on the market for $4M
The house also has a sports court and pool.
Cardinals reportedly take stance on Marvin Harrison Jr. trade rumors
This stance from the Cardinals should not be a surprise.
Alabama Politics This Week with Dale Jackson & Mecca Musick | Special Guest Assoc Atty Gen. Stanley Woodward, Jr.
RFK Jr.'s AI claims spark physician backlash as debate over medical AI intensifies
Robert F. | Robert F. Kennedy Jr., the Secretary of the Department of Health and Human Services, said on Tuesday that artificial intelligence can provide patients a second opinion that is "much better informed than any doctor in the country."
Incarnate Word vs. Michigan State Exhibition: How to Watch
Tom Izzo debuts a top-10 recruiting class at the Breslin Center, giving Jeremy Fears Jr. and new Spartans a high-energy tune-up during the legendary Izzone Campout.
30 homers are complicating the Yankees’ October lineup
Luis García Jr. did not need a long postseason audition. He homered Wednesday as the Yankees finished off Boston, adding […]
Denzel Bentley signs with Zuffa Boxing and will fight Shane Mosley Jr at Copper Box Arena on November 7 live on Sky Sports
Denzel Bentley will fight Shane Mosley Jr on November 7, live on Sky Sports; Bentley has signed a multi-fight promotional deal with Zuffa Boxing and his clash with Mosley Jr will take place on Zuffa Boxing 12, headlined by Chris Billam-Smith vs Cheavon Clarke
'The Swan: Behind The Mirror' director Erin Lee Carr on the doc's shocks and flock
New to Hulu, this documentary will have you raging over the 2004 reality TV nightmare.
Detroit Harvest Fest adds movies, more food trucks in year 6
Detroit Harvest Fest returns to the Ralph C. Wilson Jr. riverfront park with 40 food trucks, live music and outdoor movie screenings.
Laurels and Darts: Following the political money.
Illuminating campaign finance reporting from LAist on the city’s mayoral race. Plus: A poor choice of words in the Cornell case, and the value of five-dollar obituaries.
Affordability is on voters’ minds in Pa. swing districts as the cost of gas and groceries skyrockets
The cost of living is the rise as the war in Iran continues. That could hurt Trump-aligned incumbents in key Pennsylvania swing districts.
Gov. Sherrill launches working group to examine NJ public employee health benefits
TRENTON, N.J. — Gov. Mikie Sherrill has launched a working group bringing together state officials, unions, health care organizations and other stakeholders to develop recommendations aimed at improving the affordability …
Harold Fannin Jr. visits the end zone again on TNF
Harold Fannin Jr. managed just 27 yards on three receptions but did score his third touchdown of the season in Week 4.
Michael Pittman Jr. invisible once again in Week 4
Michael Pittman Jr. was held to two catches for 15 yards during the team's Week 4 matchup with the Cleveland Browns.
Travis Etienne Jr. placed on Injured Reserve
Saints RB Travis Etienne Jr. on Injured Reserve because of hamstring injury
Corus Entertainment Announces Amendment To Credit Facility
Corus Entertainment Inc TSX:CJR.B:
Saints lose $47M free agent acquisition to injured reserve
Another cornerstone of the New Orleans Saints offense is going on injured reserve. Travis Etienne Jr. must miss at least the next four weeks.
50 children in our area hit by cars every year; toxic pond water in Centennial Park; ‘gas station heroin’; plus other stories with Vanderbilt Health sources
In a news report following a Murfreesboro child who was killed by an automobile, reporter Amber Jayanth from WSMV Channel 4 News cited statistics gathered at Monroe Carell Jr. Children’s Hospital at Vanderbilt about pediatric pedestrian injuries. Trauma registry data from Monroe Carell indicates that about 50 children per year on average are treated after being hit by a car. William Schaffner, MD, Professor of Preventive Medicine, was quoted by several news outlets about public health issues, including: CNN (mRNA flu vaccine); ABC News and the American Journal of Managed Care (Pennsylvania measles outbreak); News Channel 5 (blue-green algae in the pond at Centennial Park, which can release toxins that make people and pets sick). WSMV Channel 4 News interviewed Saumya Aujla, MD, Assistant Professor of Clinical Physical Medicine and Rehabilitation, about the health risks of kratom, sometimes called “gas station heroin,” and why Tennessee banned the drug. WTVF News Channel 5 interviewed Brianna Smith, MD, Assistant Professor of Pediatrics, Hematology/Oncology at Monroe Carell Jr. Children’s Hospital at Vanderbilt for a piece on Childhood Cancer Awareness Month. Prevention interviewed Mitchell Gigandet, MD, Assistant Professor in the Neuro-Sleep Division, for a story about MDPI research on caffeine that used EEG imaging to see how the drug impacts sleep. It was found that caffeine may make sleep less restorative even when you fall asleep normally and stay in bed for eight hours. The Wall Street Journal reporter Laura Landro interviewed Joseph Schlesinger, MD, Professor of Anesthesiology Critical Care Medicine, for a story about ICU alarms keeping patients from getting sleep and creating alarm fatigue for nurses. Billboard reporter Melinda Newman interviewed country star Dasha about her upcoming vocal surgery at Vanderbilt Health. The story was picked up by numerous print and radio outlets including People.
Central Catholic Jr./Sr. High School ‘sending silence packing’ through traveling mental health exhibit
The traveling exhibit is stirring up conversations surrounding mental health.
Science Lab: Joey Porter Jr. trade to Cowboys — the Great, the Good, the Hmm...
Welcome to "The Science Lab", a place where football facts and in-depth analysis always triumph over feelings.
Yaya Diaby, Josiah Trotter, Chris Godwin return to practice
Some Bucs starters who had previously missed practice are trending in the right direction. Outside linebacker Yaya Diaby (calf/shoulder), rookie linebacker Josiah Trotter (shoulder), receiver Chris Godwin Jr.
Steelers updated mock draft after the Joey Porter Jr. trade
We've updated our three-round mock draft to include a replacement for recently traded cornerback Joey Porter Jr.
Apple TV Just Updated Its Selection of 'Bonus' Movies
Starting today, the Apple TV streaming service is offering a new selection of "bonus" movies in the U.S., Canada, the U.K., and some other countries. While competitors like Netflix offer an extensive catalog of movies from various studios, Apple TV primarily offers its own original films produced by Apple.
Shuhai Xiao awarded Clifton C. Garvin, Jr. Endowed Professorship
A paleontologist and an internationally recognized expert in the evolution of early life on Earth, Xiao has received numerous awards and honors, including induction into the National Academy of Sciences in 2023.
Joey Porter Jr. Trade Gives Steelers Fresh Start
Former Pittsburgh Steelers head coach Mike Tomlin always said he wanted volunteers and not hostages. It turns out general manager Omar Khan and current head coach Mike McCarthy feel the same way with the Joey Porter Jr. trade news that broke just after 11:30 P.M. Wednesday. The Steelers acquired a 2028 2nd-round pick and a …
Former Penn State Star Cornerback Involved in Major NFL Move
The Pittsburgh Steelers traded former Penn State star Joey Porter Jr.
Lions Miss Out on Joey Porter Jr.
Joey Porter Jr. is officially off the market, but Lions fans shouldn’t panic. Brad Holmes passed on the blockbuster move, and Detroit may have a much bigger opportunity waiting before the trade deadline.
Where UW Offensive Line Has Fallen Short
Quarterback Demond Williams Jr. has been pressured 58 times this season. In just four games, that number is the highest among quarterbacks in the Big Ten and tied for fifth-most nationally. Of the 58 pressures, 35 of them have been attributed to the offensive line, while the remaining 23 are credited to Williams himself. Washington …
Utah Jazz Remain Underrated Entering 2026-27 Season
Armed with Jaren Jackson Jr.’s elite defense and Darryn Peterson’s arrival, a revamped roster looks to defy betting lines and vault from the cellar into playoff contention.
Giants Made Right Decision in Joey Porter Jr. Sweepstakes
The New York Giants made the right decision not to trade for Joey Porter Jr.
How Is The Federal Government Counting Measles Deaths?
Recently Secretary of HHS Robert F. Kennedy, Jr., changed how the federal government tracks deaths in its official measles tally, after Pennsylvania reported four deaths. This Policy Watch reviews the two roles, strengths, and weaknesses of the two public health surveillance systems at the center of this change: the Nationally Notifiable Diseases Surveillance System (NNDSS) and the National Vital Statistics System (NVSS).
Inside Business Matters: Micron, forever chemicals, data centers, more (how to sign up)
Every Thursday, the Business Matters newsletter gathers Syracuse.com’s most insightful, noteworthy business journalism for readers.
Steelers trading CB Joey Porter Jr. to Cowboys
Late Wednesday night, general manager Omar Khan shipped the budding young cornerback to the Dallas Cowboys for a package that includes a second-round pick, per NFL insider Ari Meirov.
Pittsburgh Steelers Trade Joey Porter for 2 Draft Picks
The Steelers are trading Joey Porter Jr. to Dallas for two draft picks after the Detroit Lions reportedly showed interest in the cornerback.
L.A.-raised comic Jack Assadourian Jr. turns his Mexican Armenian roots into fearless new comedy special
Comedian Jack Assadourian Jr. on exploring his Mexican and Armenian roots through humor, family and his journey to embracing his identity.
Jimmy Kimmel's monologue gets interrupted by a baseball bat-wielding Robert De Niro
"Do you feel threatened by me?"
Cowboys send Steelers 2027 sixth-round pick and 2028 second-round pick for Joey Porter Jr.
Lions’ Joey Porter Jr. Pursuit Takes Unfortunate Turn
The Detroit Lions, who are 2-1 through the first three games of the 2026 NFL season, are not only dealing with multiple injuries to key players but a struggling secondary that has brought into question their defense.The Lions have been linked to Pittsburgh Steelers cornerback Joey Porter Jr., who seemed like a natural fit for […] The post Lions’ Joey Porter Jr. Pursuit Takes Unfortunate Turn appeared first on HEAVY.