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LAPD seizes $1M in stolen shoes, backpacks from Chatsworth business
The recovered merchandise included shoes from Brooks, Hoka, New Balance, Adidas, On and Salomon, as well as JanSport backpacks.
Want to Lower the Cost of Living? Unrig our Democracy.
Going into the midterms, voters are feeling the squeeze in their wallets and need relief. The answer lies in holding accountable politicians who prioritize their wealthy benefactors over them.
FF EAI Robotics Ecosystem (FFR) Completes Acquisition of FFAI Robotics Business, Establishing a Nasdaq-Listed Humanoid and Bionic Robotics Platform October Robot Sales Expected to Exceed 300 Units; Unveils FF OmniMind, a Unified AI Brain for All Robots
FF EAI Robotics Ecosystem Inc. (NASDAQ: FFR) ("FFR" or the "Company") a U.S.-based Embodied AI robotics company, today announced at the deal closing and its first Investor Day event in New York that it has completed its acquisition of the robotics business and related assets of Faraday Future Intelligent Electric Inc. (NASDAQ: FFAI) ("FFAI" or "Faraday Future") on October 23, 2026. The related business operations and assets have been transferred to FFR, and FFR has issued and delivered common sh
Experts Weigh In on Emerging Tool To Prevent Medical Debt
Watch our conversation about the promise and challenges of presumptive eligibility and read answers to audience questions.
Tom Brady, Candice Swanepoel have been dating since June: report
Football hero Tom Brady and supermodel Candice Swanepoel have reportedly been dating since June. The pair have kept the relationship quiet by spending time together in Indian Creek, Fla., 30
Natalie Portman says being sexualized as a child star forced her to become a 'good girl' as protection
Natalie Portman reveals how she built a "good girl" persona to counter childhood sexualization in Hollywood and why it became a lasting trap.
New Project Lets Nintendo Switch Games Run Natively on Apple Silicon Macs and iPhones
An open-source project called nxnative lets Nintendo Switch games run natively on Apple Silicon, without an emulator in between. Built by developer seedds, the tool takes a user's own game files and prod.keys and turns them into an app for iPhone, iPad, or Mac. YouTuber Andrew Tsai put it to the...
Epic Games CEO calls Steam's AI disclosure policies "a political act"
CEO of Epic Games, Tim Sweeney, has once again slammed Steam's AI disclosure policy, calling the company's position on …
Pat McAfee calls out Colts interim GM for casual attire
Pat McAfee might not always dress to impress, but that won’t preclude him from demanding more of interim Indianapolis Colts general manager Ed Dodds. In his first game as interim Colts general manager, Dodds showed up to the field in a sweatsuit, carrying a brown paper bag and wheeling his suitcase across the turf in…
LuminoCity Expands Its B2B Entertainment Business, Showcasing Immersive Experience Solutions at IAAPA Expo 2026
/PRNewswire/ -- LuminoCity Festival (LuminoCity Inc.), an immersive entertainment company specializing in large-scale light shows, animatronic attractions, and...
The science of fear: Why some love to be scared, while others hate it
Do you enjoy the thrill of scary movies, haunted houses, and Halloween decorations that jump out at you? Why do some people love to be scared and others simply hate it? Experts say part of the answer begins deep in our brain.
Report: Silent Hill 1 Remake Targeting 2027 Release, First Cast Details Revealed
Following the critical and commercial success of the Silent Hill 2 remake, fans were left eager for more modern takes on classic entries. Bloober Team answered that call last year…
Savannah women’s health night to focus on menopause education
Learn about menopause, perimenopause and symptoms at a Savannah women’s health night Oct. 29 at St. Joseph’s/Candler’s community resource center.
Longtime Los Angeles Times sportswriter Ross Newhan dies at 89
Southern California baseball fans are mourning the loss of a legendary writer. Ross Newhan, longtime baseball writer for the Los Angeles Times and columnist for the Long Beach Press-Telegram, died Sunday at 89. Newhan began his career at the Press-Telegram in 1961 before moving to the Times in 1968, where he covered both the Angels and Dodgers for the next 11…
Pricey cookie vendor closes dozens of locations nationwide
Crumbl, the high-end dessert chain serving up oversized cookies, has closed a swath of stores nationwide including seven in California. Two of the shuttered cookie shops are in Southern California,
Yankees Linked to Trading Star Slugger for Gold Glove Outfielder
New York Yankees general manager Brian Cashman could have an advantage in the sweepstakes for a prized outfielder on the market. The post Yankees Linked to Trading Star Slugger for Gold Glove Outfielder appeared first on HEAVY.
PHP Issues Second Windows Security Update in Five Days to Fix Brotli Code Execution Flaw
PHP updates Windows builds 8.2 through 8.5 to fix a Brotli flaw that could enable code execution through automatic cURL decompression.
Jon Batiste shares health update on wife's cancer battle with sweet selfie
Jon Batiste – whose wife, Suleika Jaouad, is battling cancer – shared new photos of the couple on social media amid Jaouad's treatment.
You can now run Nintendo Switch games natively on iPhones and Macs
This works because the Switch and Apple's recent devices both use Arm-based processors, meaning a game's instructions are already compatible with an iPhone's chip. PC ports like...
Zelda 40th Anniversary Switch 2 Pro Controller restock tracker: we’re watching these retailers
🎮 Nintendo will release a Zelda 40th anniversary Switch 2 Pro Controller on October 29 💰 It costs $99.99, the same as other limited editions 📅 A restock could occur on launch day at Walmart and Best Buy 🚨 Our Zelda Switch 2 Pro Controller restock tracker @mattswider on X will send out an alert when stock appears Walmart: Zelda Pro Controller Best Buy: Zelda Pro Controller Amazon: Zelda Pro Controller Target: Zelda Pro Controller GameStop: Zelda Pro Controller Nintendo is releasing a special limited edition Nintendo Switch 2 Pro Controller to celebrate the 40th anniversary of The Legend of Zelda series. It releases on October 29, 2026, which is when we expect to see a long-awaited restock of the hard-to-find controller. 🚨 We’re tracking Zelda Switch 2 Pro Controller stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 The Switch 2 Pro Controller features the same striking gold and royal emerald color scheme of the Nintendo Switch 2 The Legend of Zelda 40th anniversary edition, and also includes a fun little easter egg on the back: an 8-Bit Link. 🚨 Want the Zelda 40th Anniversary Switch 2 Pro Controller? Drop your email for restock alerts before it sells out. ⤵️ Subscribe This is the same Nintendo Switch 2 Pro Controller we’re used to, aside from the intricate design, but it means you’ll have to pay more as a result. It costs $99.99 instead of the standard $89.99. However, the Pro Controller is the easiest way to play the best Switch 2 games in TV mode. If you’ve been searching for a Zelda 40th Anniversary Switch 2 Pro Controller restock, here’s everything you need to know. Zelda 40th anniversary Switch 2 Pro Controller should restock at these retailers We’ve seen retailers such as Walmart and Best Buy restock items on release day, even when pre-orders have sold out. It’s likely that the Zelda Switch 2 Pro Controller will be up for grabs on October 29, 2026, when the controller and console launches. Demand will be high, and stock could sell out fast. However, we’ll be keeping a close eye on every major retailer, including Target, Amazon, GameStop, and the Nintendo Store and will alert our followers as soon as stock goes live. Why you can trust our Zelda Switch 2 Pro Controller restock tracker We’ve already helped over 400,000 people buy a PS5 when it was in and out of stock during Covid, and we’ve helped our subscribers continue to secure hard-to-find items. The Shortcut followers were some of the first to secure the Switch 2 when it went on sale, and we’ve also helped countless others snag limited edition consoles like the PS5 30th anniversary edition. The Shortcut and Matt Swider on X offer exclusive Zelda 40th anniversary Switch 2 Pro Controller restock updates with up-to-the-second US store inventory checks at the biggest retailers. You’ll receive an instant notification on X (if set to on) as soon as new stock arrives. Up next: Call of Duty: Modern Warfare 4 review roundup: ‘a strong return to form’ Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.
Mac DeMarco review – glowing melodies and shirtless antics at Carnegie Hall
After winning over gen Z, the cult indie rocker makes the historic venue swoon with introspective anthems and a Michael Jackson cover
EQS Group receives validation of its climate targets by the Science Based Targets initiative
EQS Group, a global leader in agentic AI SaaS for compliance, today announced that the Science Based Targets initiative (SBTi) has successfully validated EQS Group's near-term and net-zero greenhouse gas (GHG) emissions reduction targets.
HKSTP Partners with Leading Science and Technology Company Merck to Open a New Chapter in I&T Collaboration
EQS Newswire / 26/10/2026 / 17:15 CET/CEST New Merck Hong Kong Centre to Connect Global Expertise with Local Innovators and Accelerate R&D Commercialisation HONG KONG SAR – Media OutReach Newswire – 26 October 2026 – Hong Kong Science and Technology Parks Corporation (HKSTP) and Merck, a leading…
Key West Chamber of Commerce showcase connects business & community
The Key West Chamber of Commerce’s 37th annual Showcase of Key West Businesses took place Oct. 14 at the Casa Marina, sponsored by Mount Sinai Florida
Utah House District 68: Sonya Ray and Scott Chew
Constitution Party candidate Sonya Ray answered Utah Public Radio's questionnaire on why she's running for State House District 68 and what issues matter the most for her.
Build-a-manager: LL staff edition
Sweet Lou aside, making a list of some qualities that are the most important to the LL staff in a manager
Ken Paxton’s State-Funded Jet-Setting Draws Campaign Scrutiny
Mr. Paxton, the Republican candidate for Senate in Texas, has taken about 350 trips outside of the state since he was sworn in as attorney general.
📈 Monday data: The bottleneck isn’t intelligence
In the AI Investment Brief today: CapEx updates and lease commitment breakdowns Anthropic co-founder Jack Clark recently said in a speech at the IMF that the singularity has begun: For many years, researchers and science fiction authors have forecast a future in which AI systems drastically increase the pace of overall scientific and technical progress, making things move so quickly that it is hard for humans to keep up. They call this the singularity. I believe that this year we have gained convincing evidence that it has now begun. This follows Anthropic’s claim that in August, 26% of its AI R&D was led by Claude, with a human supervising its work. In October, OpenAI posted 719 math manuscripts1 made by its internal model. Math and coding are two fields where a research loop can close without leaving the desk. But can the loop close in the rest of science? Subscribe The loop is real The idea is not new. Mathematician Irving John Good, who had worked with Alan Turing at Bletchley Park, argued that a machine smarter than us “could design even better machines; there would then unquestionably be an ‘intelligence explosion,’ and the intelligence of man would be left far behind.” The Gödel machine, a self-improving computer that can rewrite its own code better than its prior, was first proposed in 2003. In 2025, researchers at Sakana AI and the University of British Columbia set out to show that this was possible. Their agents iteratively improved their own code through a feedback loop, resulting in gains of 30 pp on SWE-bench and more than 15 pp on Polyglot, testing coding skills beyond Python. The idea has since been tested in other labs. A Gemini-powered agent called AlphaEvolve found a faster matrix multiplication kernel used for training Gemini, speeding up the kernel by 23% and cutting Gemini’s training time by 1%. In China, MiniMax reported that its M2.7 model worked on improving its own agent’s harness, skills, sampling and memory. Over 100 rounds of rewriting led to a 30% gain, per its internal evaluations. In each case, what was being rewritten was not the model itself but everything around it. Is it better than human work? In September this year, in what seemed like a milestone, an AI-built agent proved as good at improving other AI agents as a human-built one. It did that in what appeared to be half the steps. But the result was inconclusive: the differences between runs were greater than the difference between the AI- and human-built agent results. Nonetheless, this is increasing the chatter around recursive self-improvement (RSI) in AI. Google’s Sundar Pichai said that “you have RSI loops along with AI researchers in various aspects of model development.” Sakana AI published a paper on RSI through multi-agent collaboration, finding that after two cycles its system scored 1.2–1.6x better per output token than the base model across four research benchmarks. Ramez Naam challenges that view. He splits AI self-improvement into five overlapping types. The first four describe how autonomous the AI is; so far, only types 1 and 2 have been observed. The fifth type describes accelerating returns, and he notes that greater autonomy doesn’t guarantee a takeoff scenario. Instead, each round of self-improvement would need to deliver at least as much as the last. The results from Sakana, AlphaEvolve and MiniMax above might look like type 3 or type 4 autonomy. But in each case, the AI wasn’t updating its own weights directly, only the ancillary parts — the harness, the memory. And where Claude leads its own R&D, for now a human still supervises.
New Twin Cities Lab Changing The Landscape Of Health
Human Powered Health is strengthening its mission to help motivated people improve their health and longevity with the opening of an expansive human performance lab. Featuring an array of physiological assessments, longevity and athletic performance services, the state-of-the-art technology and health optimization services once reserved for elite athletes are now accessible and available for everyone.
AGFA HealthCare Selected by Infirmary Health to Modernize Imaging Across Its Health System
Enterprise Imaging Cloud investment advances Infirmary Health's strategy to modernize imaging, simplify radiology workflows and create a scalable foundation for continued growth.CARLSTADT, NJ / ACCESS Newswire / October 26, 2026 / Infirmary Health has selected Enterprise Imaging Cloud (SaaS) to modernize its radiology imaging environment and establish a foundation for a broader Enterprise Imaging strategy across the health system.
Development battles, business worries and election season in Brunswick
Development projects, early voting, fatal collisions, business closings and more are pushing Brunswick County residents to the brink as October winds down.
Development battles, business worries and election season in Brunswick
Development projects, early voting, fatal collisions, business closings and more are pushing Brunswick County residents to the brink as October winds down.
Women’s Heart Health Care Starts at Puberty: New Shared Framework from Leading Medical Societies
The American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine released landmark publications that redefine women’s heart health, starting at puberty. Amanda Marma Perak, MD, MSCI, a pediatric cardiologist at Ann & Robert H. Lurie Children’s Hospital of Chicago was the Vice-Chair of the collaborative writing group.
NASA's Swift Observatory Ends Its Science Mission
NASA's Swift observatory made its last observation on Oct. 20 after 22 years, 2,000-plus gamma-ray bursts and about 7,000 papers.
INEOS puts Lausanne-Sport up for sale: Are Jim Ratcliffe’s sports investments working?
The Manchester United minority owner's company bought the Swiss club in 2017 — but the INEOS empire is now in retreat.
Hackers Begin Dumping Nintendo Switch 2 Games As Expanded Exploit Breaks Console Security
New exploit allows for game dumps, but will probably be patched soon
Tim Hill goes out with a whimper after uneven campaign
After an exemplary start to the year, the veteran southpaw unraveled down the stretch in what could be his swansong
The Art of the Sweet Science: Stunt Coordinator Clayton Barber Talks Bringing ‘The Greatest’ to Life
Actors Jaalen Best and Omari Hardwick spent countless hours being drilled on the finer points of boxing in front of the camera.
Voices: Eight hours after being in crisis, I was expected to return to normal life. We need better mental health support.
“Mental health care should be accessible, affordable and compassionate,” Emilee Swensen writes in an op-ed. “The way people are treated matters.”
Scientists solve mystery of 1,000-mile cloud floating on Mars
Space enthusiasts and astronomers have been tracking one of the Red Planet’s most fascinating atmospheric mysteries for years: a colossal plume officially known as the Arsia Mons Elongated Cloud (AMEC). AMEC was first discovered in 2018 and quickly became one of the most elusive answers for scientists. Researchers have now resolved this mystery using the […] Read the original article here: Scientists solve mystery of 1,000-mile cloud floating on Mars
Rezilient Health Appoints Lisa Ness as Chief Revenue Officer
Rezilient Health announced today that Lisa Ness, MBA, RD, CDE, has joined the company as Chief Revenue Officer. Ness brings more than 30 years of healthcare industry experience, including executive leadership roles at QuadMed, CareATC and Proactive MD. In her new role, she will lead Rezilient's commercial growth strategy as the company expands its relationships with self-funded employers, brokers and health systems nationwide.
Partner1 Renews WBENC Women's Business Enterprise and Women-Owned Small Business Certifications
Recertification caps a year in which founder and CEO Juhi Saha was named to Inc.’s 2026 Female Founders 500 and Partner1 was named an Inc. Power Partner for the second year runningPLEASANTVILLE, N.Y., Oct. 26, 2026 (GLOBE NEWSWIRE) -- Partner1, the advisory firm and software platform behind the partnership strategies of fast-growing B2B software companies, today announced it has renewed its Women’s Business Enterprise (WBE) and Women-Owned Small Business (WOSB) certifications from the Women’s Bu
Singapore Airlines KrisWorld and Starlink Wi-Fi Upgrade 2027
Singapore Airlines plans to upgrade KrisWorld with 4K screens, better sound, & Starlink Wi-Fi from 2027. Find out what passengers can expect.
After AI help, participants skipped tasks without chatbot more often
A study of 1,222 people found that participants who used chatbots for simple tasks were more likely to skip exercises or answer incorrectly after AI access was removed.
The markets are starting to act seriously weird. Blame AI
AI’s shaky balance sheets raise questions about circular financing that investors have long questioned but the industry and many traders have swept under the rug.
Liza Minnelli bombed in many movies. So why do people still love her?
ASK MICK LASALLE: The Chronicle movie critic emeritus answers questions about Liza Minnelli, Dolly Parton and his favorite documentaries, with 11 films he says are worth seeking.
Epic Games Boss Tim Sweeney Doubles Down on Valve Criticism, Says Steam's AI Content Disclosure Is a 'Political Act'
Epic Games boss Tim Sweeney spent the weekend doubling down on his severe criticism of Valve, calling Steam’s AI content disclosure a “political act.”
Nintendo Switch 2 gets its first list of Xbox achievements with Minecraft
Minecraft launches on Nintendo Switch 2 on October 27 and includes its own set of Xbox achievements to unlock on Nintendo's console.
Are these NFL teams actually good? Plus, a gruesome NBA injury
The Pulse Newsletter 📣 | This is The Athletic’s daily sports newsletter. Sign up here to receive The Pulse directly in your inbox. Good morning! Score 50 points today. Coming up: 🏈 A wild Week 7 💔 Williams carted off 🎠 Coaching carousel in full swing There is still so, so much time left in the NFL season. But after another baffling batch of games yesterday, I could not resist simply looking at the division standings and cackling at our current reality. Are some of these teams actually good? Are the teams we thought were good actually just OK? Do we know anything? ...
Boyz II Men swap R&B for country on new album
Boyz II Men have officially entered their Cowboyz II Men era.
Exclusive-US Political Candidates Tailor Messages for AI Models Used by Voters
By Mike Stone WASHINGTON, Oct 26 (Reuters) - US political candidates have been engineering their campaign messages to appeal to the AI chatbots that more voters have been using to answer questions about issues, and documents seen by Reuters have revealed some of their strategies. One Powerpoint ...
Gen Z has buyer’s remorse on Trump
Experts in the youth vote explain a dramatic swing toward Democrats — and its limits.
Mayor Bibb is building a national profile. Cleveland’s voter turnout is the question hanging over it.
Cleveland's Mayor Bibb is pursuing a national profile but voter turnout may hamper those efforts.
Singapore Airlines upgrades in-flight entertainment with next-gen KrisWorld
Singapore Airlines (SIA) is enhancing its in-flight entertainment experience with next-generation KrisWorld and high-speed connectivity, giving customers more c...
Americans for Prosperity dropped its support for Martina White and other GOP lawmakers over their prevailing-wage vote
The right-leaning group has pulled its endorsements at a time when Republicans in swing districts may need all the help they can get.
10 minutes is all it takes for AI assistance to erode your motivation, study shows
In a set of problem-solving experiments, researchers found that people who used AI to get answers were more likely to give up and fail when that help was removed, compared with people who did not use AI.
Local shops welcome costumed crowds ahead of Halloween
The Volkswagen parking lot was delightfully frightful on a spooky Saturday. Kids of all ages had a chance to test run their Halloween costumes, collect
Business News: Audemars Piguet Unveils 'The Watch Keepers' - A Digital Platform Offering Certified Pre-Owned Watches
The Le Brassus watchmaker will facilitate sales and auctions of brand-certified timepieces on a digital platform launching in Switzerland and Europe, with plans for expansion to other markets, including the U.S.
KC has no answers for Jaxon Smith-Njigba on SNF
Jaxon Smith-Njigba led all players in targets, receptions, and total yards as part of a dominant effort versus the Kansas City Chiefs in Week 7.
Cris Collinsworth Turns Heads With Unusual Praise of Patrick Mahomes
Announcer Cris Collinsworth was criticized after he praised Chiefs quarterback Patrick Mahomes for recovering a fumble. The post Cris Collinsworth Turns Heads With Unusual Praise of Patrick Mahomes appeared first on HEAVY.
Ted Sarandos Swoops Into Seoul as Netflix Celebrates 10 Years in Korea
The streaming gaint's co-CEO joined stars from ‘Squid Game,’ ‘KPop Demon Hunters’ and other Korean hits for a two-day fan festival, while previewing buzzy upcoming titles like ‘Possible Love,’ ‘Tantar...
Fabarta Unveils Major Upgrade to Its AI for Science Platform, Named Among Inaugural "Hong Kong Top Talent Ecosystem Partners" Ahead of Hong Kong FinTech Week
PR Newswire | Powered by the upgraded RSI engine, the platform unifi
LaVine Scores 37, But Grizzlies Grind Down Kings Late
Ty Jerome’s clinical free-throw shooting fueled an unbeaten Memphis start, spoiling Zach LaVine’s offensive outburst and leaving the winless Kings searching for answers after a late-game collapse.
Psychology says children who carry the same toy from room to room may be seeking more than entertainment
it offers familiarity, comfort and a sense of security as they navigate an unfamiliar or overwhelming world.
Who Should Lead Off for the A's in 2027?
Henry Bolte thrived leading off the final six weeks of the 2026 season, but heading into 2027, Zack Gelof may be the answer.
How to Manage Symptoms of Heart Failure
(Feature Impact) Americans are facing a growing health challenge, with 1 in 4 adults at risk of heart failure, according to the Heart Failure Society of America. Additionally, approximately 6.7 million U.S. adults who are 20 years old or older are currently living with heart failure, and that number is projected to reach 8.7 million by 2030. googletag.cmd.push(function() { googletag.display('JGFI_Article_300x250'); }); Managing heart failure is a significant expense to the U.S. healthcare system, costing the nation approximately $40 billion in 2020 and expected to increase to approximately $142 billion a year by 2050.If you (or a loved one) are living with the condition, consider these tips to help manage it.Adhere to the Treatment and Follow-Up PlanOngoing outpatient care is important when managing heart failure. Understand the treatment plan provided by your healthcare team, make diet and lifestyle changes, take medications as directed and keep recommended follow-up appointments.Pay attention to changes in symptoms and communicate with your healthcare provider if treatment does not seem to be working as expected. If their conditions are left unmanaged, patients can experience a range of heart-failure-related symptoms such as shortness of breath, fatigue, buildup of fluid and more.Understand Challenges with Diuretic TreatmentDiuretics help the body remove excess fluid and are commonly used to treat swelling, or edema, associated with heart failure. Your provider may try different diuretics, sometimes referred to as “water pills,” to manage your heart failure symptoms. However, intravenous (IV) diuretic therapy may be required for some patients if symptoms continue.Ask About Treatment Options Before IV Care Is NeededFor some adults, a healthcare provider may consider recommending an at-home, non-oral diuretic option prior to escalating to IV therapy.For example, ENBUMYST™ (bumetanide nasal spray) is a prescription diuretic used in adults to treat edema associated with congestive heart failure. It’s administered as a nasal spray for short-term use to manage excess fluid with the goal of transitioning to oral diuretic therapy when appropriate.Talk with your healthcare provider to learn more and visit enbumyst.com. Read the full Prescribing Information and Patient Information.Photo courtesy of Shutterstock googletag.cmd.push(function() { googletag.display('JGFI_Article2_300x250'); }); Important Safety InformationWhat is ENBUMYST?ENBUMYST is a prescription medicine used in adults to treat swelling caused by excess fluid in the body (edema) from congestive heart failure, liver disease, and kidney disease.What is the most important information I should know about ENBUMYST?ENBUMYST is a diuretic that helps your body remove fluid. Losing too much fluid can cause dehydration, low blood volume, and increase the risk of blood clots. Blood abnormalities may include decreased salts (electrolytes), and increased nitrogen, glucose and uric acid. The risk of these abnormalities is higher in elderly people, those using higher doses, or those who do not get enough electrolytes by mouth.You should not use ENBUMYST if you have severe electrolyte loss. Tell your healthcare provider if you experience unusual thirst; dizziness or lightheadedness; weakness or tiredness; fast heart rate; dry mouth or tongue; sudden pain; redness or swelling in your joints; pain, swelling, redness, or warmth in your leg; shortness of breath or fast breathing; high blood sugar; dark urine; pale, tight, cool or clammy skin; muscle cramps; confusion.Do not use ENBUMYST if you have low or no urine production or are allergic to bumetanide or to any of the ingredients in ENBUMYST.Before using ENBUMYST, tell your healthcare provider if you have low electrolytes, are on a low-salt diet, have diarrhea, diabetes, nasal problems such as a runny or stuffy nose or polyps, a history of nasal injury or surgery, are or plan to become pregnant, are or plan to breastfeed.Tell your healthcare provider about all the medicines you take, including prescriptions, over-the-counter medicines, vitamins, and herbal supplements.ENBUMYST may cause serious side effects, such as worsening kidney function and ringing in the ears or hearing loss.The most common side effects of ENBUMYST include dehydration, headache, muscle cramps, dizziness, low blood pressure, nausea, and abnormal brain functioning with certain liver problems.These are not all the possible side effects of ENBUMYST. Talk to your healthcare provider for more information.Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.US-ENBU-2600110 googletag.cmd.push(function() { googletag.display('JGFI_Article3_300x250'); });
Frighteningly fun films for Halloween
With autumn finally here and spooky season in full swing, what better way to celebrate than by watching a fun, creepy film? Whether you prefer horror films or nostalgic childhood
‘End game’: Taylor Swift and Travis Kelce mocked by opponent
The Seattle Seahawks handed the Kansas City Chiefs their first loss of the season on Sunday night, and they made sure to rub it in afterward by trolling newlyweds Travis Kelce and Taylor Swift. After their 20-3 win on Sunday Night Football, the Seahawks posted a Swift-themed troll on social media, sharing a friendship bracelet…
Raptors’ Kawhi Leonard to undergo testing after concerning injury update
Kawhi Leonard was missing in action on Sunday, as the Toronto Raptors lost to the Minnesota Timberwolves , 117-94, at Target Center. The Raptors fell to 2-1, while the Timberwolves improved to 3-0. Leonard was added to the injury report just an hour before tip-off. Toronto announced that the veteran forward was dealing with swelling in his left […] The post Raptors’ Kawhi Leonard to undergo testing after concerning injury update appeared first on ClutchPoints.
Connections: Sports Edition today: Hints and answers for Oct. 26, 2026, puzzle No. 763
Welcome to Connections: Sports Edition Coach — a spot to gather clues and discuss (and share) scores.
Everything Evanston: Fall flavors ramp up spirit, business in Evanston coffee shops
Autumn in Evanston brings seasonal menus and seasonal rushes as coffee shops fill with fall customers. SAMI HELLER: With the weather beginning to fall below 60 degrees, it’s time to ‘fall’ into the season of spooky movies, light sweaters and pumpkin spice. The Daily went into Evanston to see what the season of color-changing foliage...
Anthony Scaramucci Says Vivek Ramaswamy 'Disgraced Himself' in Ohio Governor Race: 'He’s Finished Himself as a Future Candidate'
SkyBridge Capital founder Anthony Scaramucci accused Ohio gubernatorial hopeful Vivek Ramaswamy on Sunday of abandoning his core political principles to win the high-stakes race.Scaramucci’s Scathing ...
Why Fulton County is at the center of Georgia politics
Over the past decade, Georgia has become a closely watched swing state thanks to Fulton County's emergence as a political powerhouse—and the focal point of Donald Trump’s efforts to challenge his 2020 election loss—but its influence wasn’t always so pronounced.
What's fair game in politics?
Jim Lokay discusses the controversy over Vivek Ramaswamy's attack ad involving his opponent Amy Acton's estranged mother, plus how affordability arguments are shaping the last week of the midterm campaign with Andrew Donaldson of Ordinary Times.
Cubs Trade Of Edward Cabrera An Early Lose-Lose Deal
A high-stakes gamble for Edward Cabrera backfired in Chicago as the right-hander's metrics plummeted, leaving the North Siders searching for answers amidst a looming rotation crisis.
Politics Unplugged (Full Episode) Oct. 25, 2026
On this week's episode of Politics Unplugged, host Dennis Welch and a panel break down Arizona's election landscape one week out: pessimistic voter mood, suppressed independent turnout, lagging GOP enthusiasm, and Democrats gaining ground. They discuss Elon Musk's late spending in competitive House races and debate the impact of big money flooding the state. The show also covers a widely condemned Ohio attack ad by Vivek Ramaswamy that weaponizes a rival's childhood abuse—drawing praise from Trump and Vance but bipartisan outrage.
Tiny magnetic vortices could help computers work more like your brain
Scientists have filmed tiny magnetic vortices called skyrmions melting out of an organized lattice for the first time, revealing new ways to manipulate these unusual structures. The breakthrough could help make brain-like computers a reality, potentially enabling dramatically smaller and more energy-efficient technology.
2026 KlarText Prize for Science Communication: Klaus Tschira Foundation Honors Seven Researchers
What exactly did you do in your doctoral dissertation? The Klaus Tschira Foundation honors the most compelling answers to this question with the KlarText Prize for Science Communication. On Octobe ...
Panera closes in Dillon, Underground Snowboards gets new owners and more business news
Panera Bread has closed its Dillon location less than four years after opening, adding to a growing list of national restaurant chains that have shuttered businesses in the area. The establishment at 257 Dillon Ridge...
Orlando Magic's Sean Sweeney Message to Paolo Banchero After Injury
As a grueling road trip looms, assistant coach Sean Sweeney challenges his squad to maintain their identity and intensity while navigating Paolo Banchero’s absence against elite competition.
Clemson’s Loss to Virginia Tech Puts the Program in Flux
Clemson’s loss to Virginia Tech puts the program in flux heading into November. The Tigers now find themselves on the outside looking in on the ACC Championship race after being defeated 20-16 by the Hokies. Dabo Swinney’s team played well in many spots, especially in the third quarter. The complementary football Clemson displayed to start the …
Volkswagen Bet On Xpeng To Save Its China Business, But Buyers Aren't Showing Up
Volkswagen once dominated China’s automotive market, but the rise of domestic electric vehicle manufacturers has turned its fortunes upside down. Hoping to regain lost ground, the German automaker partnered with Chinese EV specialist Xpeng in ... Read more
Ravens surrender 35 unanswered points in stunning loss to Bengals
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ESMO: Roche touts ‘convincing’ phase 3 KRAS data after win over rivals
Roche has shed more light on its investigational KRAS G12C inhibitor's phase 3 victory over Amgen’s Lumakras and Bristol Myers Squibb’s Krazati. The open-label Krascendo 1 trial enrolled 338 people with previously treated KRAS G12C-mutated non-small cell lung cancer (NSCLC). Patients who had already received a KRAS G12C inhibitor or pan-KRAS/RAS inhibitor were excluded from the trial. Participants received either divarasib once daily, Lumakras once daily or Krazati twice daily. Roche announced back in July that divarasib had demonstrated statistically significant improvements in progression-free survival (PFS) and overall survival (OS), meeting the trial’s primary and key secondary endpoints. But the Swiss pharma had been holding back the detailed data until now. At the European Society for Medical Oncology (ESMO) Congress in Madrid, Roche revealed that median OS for the 167 patients who received divarasib was 17.7 months, compared to 12 months for the 171 patients who received Lumakras or Krazati. The benefit was similarly clear when it came to median PFS, which stood at 9.8 months versus 5.7 months, respectively. A total of 44% of patients receiving divarasib were alive without disease progression at one year, compared to 24% of the control group, according to Roche’s presentation. It was a similar story for the objective response rate, which came in at 58% for divarasib versus 32% for the control group, while median duration of response was 11.9 months versus 6.9 months. Stefan Frings, M.D., Ph.D., deputy chief medical officer at Roche Pharma, told Fierce that the data made for a “very comprehensive, strong package, which should be convincing to health authorities.” “It’s an important advance for patients with lung cancer,” Frings said in an interview at a Madrid hotel during the conference. “It's a second-line setting, and patients who receive divarasib benefit compared to the current first-generation KRAS G12C inhibitors by having far longer overall survival,” he continued. “They live longer. They have better progression-free survival, better response rates, and with a safety profile which is—if [anything]—even better,” he said. According to Roche, 4.8% of patients receiving divarasib discontinued treatment due to treatment-related adverse events, compared to 11.7% in the control group. Serious treatment-related adverse events were also less common with divarasib, at 7.8% versus 15.2%. Roche’s confidence in divarasib had been building even before this phase 3 success. The candidate had already shown better potency and selectivity than the incumbent KRAS G12C inhibitors Krazati and Lumakras in preclinical tests. After cross-trial comparisons suggested that the edge translated into better clinical outcomes, Roche axed a study comparing divarasib to the chemotherapy docetaxel and went toe-to-toe with Lumakras and Krazati. “We designed the drug on purpose with higher potency and better selectivity,” Frings explained. “So, based on preclinical models, we clearly knew it would be superior to the first generation.” “It’s honestly not so frequent that pharma companies go head-to-head,” he added. “But if you want to make a point, if you want to convince payers, prescribers and patients … then a head-to-head win is rather rewarding.” While Amgen and BMS reached the regulatory finish line first for KRAS G12C-mutated, locally advanced or metastatic NSCLC in 2021 and 2022, respectively, they have struggled to capitalize on their head start. Krazati brought in $55 million for BMS in the second quarter, while Lumakras delivered $111 million to Amgen. For its part, Roche is aiming for peak divarasib sales of 1 billion to 2 billion Swiss francs ($1.2 billion to $2.5 billion), according to Frings. The Big Pharma is currently recruiting patients into a phase 3 trial comparing divarasib plus Keytruda against Keytruda plus chemotherapy in previously untreated advanced or metastatic nonsquamous KRAS G12C-mutated NSCLC. Roche has previously suggested that sales in metastatic disease would account for most of the forecast. Frings was tight-lipped on the exact timeline for a regulatory filing but said the Swiss pharma is “certainly keen to get this to as many patients as possible around the world.” Roche has more RAS drugs coming up behind divarasib. The pharma has already launched phase 1 trials of a pan-RAS inhibitor called RG6505 and a KRAS G12D inhibitor dubbed RG6620 in solid tumors. Roche’s partner Chugai Pharmaceutical is also testing a pan-KRAS inhibitor called AUBE00. Roche has made a “deliberate effort” to test a range of RAS drugs, Frings said. “If you have many rare mutations and you are scrambling to find sufficient patients, a pan-RAS inhibitor makes a lot of sense,” he explained.
Rumored Lucia Actress Goes Viral After Dodging Swarm of GTA 6 Comments During Livestream
Manni L. Perez, the actress long rumored to be playing Lucia in GTA 6, has gone viral after dodging a swarm of comments from Grand Theft Auto fans during a recent livestream.