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Texas hosting two top-10 prospects on Thursday
Monshun Sales and John Meredith are both in Austin for unofficial visits.
Dallas County GOP Chair Allen West resigns amid push for his removal
His resignation comes after he made a controversial decision among his party to return to countywide voting for the May 26 runoff.
Iran war has some Republicans worried their chances of keeping the House are slipping away
The White House had long circled Tax Day as the unofficial start to a critical midterm campaign meant to highlight how much money the administration was putting back in voters’ pockets.
UConn loses Paunovic and Furphy to transfer portal
UConn men’s basketball now has four players in the portal from the end of their bench.
The Science Behind Alaska's Northern Lights
If you want to plan a trip to see the northern lights, Alaska belongs at the top of your list. Here's why – starting with the science.
This Tamale Act could throw open the door for more home kitchen entrepreneurs in Colorado
Home tamale businesses are the impetus for a new bill giving entrepreneurs a break from regulations.
Apopka voters to decide on next Mayor in Tuesday Runoff
The runoff will be decided tonight.
'It's incredible, like science fiction': How a new wave of immunotherapy is eliminating cancers
After nearly 100 years of development, treatments that bolster the body's immune system to fight cancer are coming of age – and saving patient's lives.
Hidden weak spots in HIV and Ebola revealed with breakthrough nanodisc technology
A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed up the development of more effective vaccines.
Barcelona vs Espanyol – Predicted lineup and team news
Barcelona will look to make it seven La Liga wins in a row when they host Espanyol at the Camp Nou on Saturday.The Catalan giants have dominated this fixture in recent years — Espanyol haven’t bea...
'New king of Las Vegas' is celebrated with Strip parade
Singer-songwriter Bruno Mars was honored with a parade in his honor and a street named after him near the Park MGM in Las Vegas | Talk 1370
'New king of Las Vegas' is celebrated with Strip parade
Singer-songwriter Bruno Mars was honored with a parade in his honor and a street named after him near the Park MGM in Las Vegas | Talk Radio 1210 WPHT
'New king of Las Vegas' is celebrated with Strip parade
Singer-songwriter Bruno Mars was honored with a parade in his honor and a street named after him near the Park MGM in Las Vegas | Newsradio 1140 WRVA
The cast of 'Juno': See the stars of the 2007 Oscar winner, then and now
‘Juno’ put teen pregnancy in the spotlight and made a splash at the Academy Awards in 2007. Find out what the cast is doing now.
Harry Cohen banks $144K in Q1 for re-election, but he might wind up unopposed
Cohen's opponent doesn't live in the district.
Matrix Business Systems Builds a Better Way to Manage Print
What began as a leap from corporate to entrepreneurship is now a company redefining how organizations manage print infrastructure.
WATCH: Democratic presidential prospects flock to Al Sharpton's conference in New York
The Democratic Party's most ambitious politicians are courting African American activists in New York this week as the party's unofficial 2028 presidential nomination contest takes shape at an annual conference led by Rev. Al Sharpton.
Georgia’s 14th District runoff reveals significant shift to Democrats
A November rematch is already brewing after Republican Clay Fuller staved off Democrat Shawn Harris in Tuesday's runoff.
Republican wins runoff to replace Marjorie Taylor Greene in Congress
Republican Clay Fuller, a former prosecutor endorsed by President Donald Trump, on Tuesday won a runoff election in Georgia to replace conservative firebrand Marjorie Taylor Greene in the U.S. House of Representatives.
Republican wins runoff to replace Marjorie Taylor Greene in Congress
Clay Fuller, a district attorney backed by President Donald Trump, defeated Shawn Harris in the deeply red district vacated by Marjorie Taylor Greene.
Dallas State Senator Nathan Johnson talks about his run for Texas Attorney General
Texas Senator Nathan Johnson, D – Dallas, is running against former Galveston Mayor Joe Jaworski in the May 26th primary runoff election after neither candidate received fifty percent of the vote. The winner will take on whoever wins the Republican nominee in November; either Texas State Senator Mayes Middleton, R – Galveston, or Congressman Chip Roy, R – Austin.
Dallas County GOP chair's precinct reversal brings turmoil in party
The GOP will vote April 20 on whether to oust West as chair after he broke from the group’s earlier agreement to hold precinct-based voting for this year’s primary and runoff election days.
Georgia House Special Runoff Election 2026 Live Results
See live results from the 2026 Georgia House Special Runoff election as votes are counted.
Marketplace - Business News & Economic Stories for Everyone
Marketplace raises the economic intelligence of the country through the unorthodox story, casual conversations and unexpected angles on the news.
Georgia Runoff Puts Trump Influence to the Test in MAGA Stronghold
By Nathan Layne April 7 (Reuters) - Voters in northwest Georgia go to the polls on Tuesday in a congressional race between a moderate Democrat and a Republican backed by President Donald Trump, in a test of Trump's sway over his base and a possible barometer for the November midterms. The two-way ...
Georgia runoff to decide who replaces Marjorie Taylor Greene after her spat with Trump
Overwatch Reveals The Anran Redesign Fans Begged For
The character looked more like Kiriko and Juno than her brother Wuyang
A Redistricting War in Florida, Georgia’s Runoff and the Latest Politics News
As deadlines approach in the next two weeks, neither is going quite according to the partisan plan.
Ballots cast Tuesday, counted later: Surfside mayoral runoff results pushed to April 28, Judge rules
A Judge’s ruling creates a three-week window for additional mail-in ballots, allowing voters to request and submit them well beyond Election Day.
Yoshihisa Kishimoto, Creator of Double Dragon and Renegade, Dies at 64
Yoshihisa Kishimoto, the creator of the Double Dragon and River City (Kuno-kun) franchises, has died at the age of 64.
What to expect in Georgia's special congressional runoff to replace Marjorie Taylor Greene
Democrat Shawn Harris and Republican Clay Fuller were the top two vote-getters in the March 10 special election, but neither candidate received the vote majority needed to avoid Tuesday's runoff.
Apopka Mayor early voting starts this week as more personal accusations fly
Here's how to vote early in the heated Apopka Mayor runoff election.
Republican Clay Fuller under pressure in Georgia race to replace Marjorie Taylor Greene
The special election runoff between Republican Clay Fuller and Democrat Shawn Harris is being watched by both parties as they consider strategy ahead of the midterms.
In Race to Replace Marjorie Taylor Greene, the Iran War Is a Dividing Line
Tuesday’s special House election runoff in a conservative stretch of Georgia is one of the first to showcase disagreements over the conflict, including within the G.O.P.
Voters in Georgia have moved on from Marjorie Taylor Greene. On Tuesday, they finally fill her seat
Three months after Marjorie Taylor Greene abruptly left Washington in the midst of a remarkably bitter feud with President Donald Trump, voters in northwest Georgia on Tuesday are poised to cast their ballots – again – in a runoff election to replace her.
Preparing the Next Generation of Alcohol and Drug Counselors
UNO’s Clinical Mental Health Counseling program is expanding its reach and impact by offering students a pathway to dual licensure in both mental health and substance use counseling. In just two additional courses beyond their required coursework, students can become eligible for Nebraska’s Provisional Licensed Alcohol and Drug Counselor (PLADC) credential.
A massive arctic thaw is unleashing carbon frozen for thousands of years
A sweeping new study reveals that as Arctic permafrost thaws, it is dramatically reshaping rivers and releasing vast amounts of ancient carbon that had been locked away for thousands of years. By analyzing decades of high-resolution data across northern Alaska, scientists found that runoff is increasing, rivers are carrying more dissolved carbon, and the thawing season is stretching further into the fall. This carbon eventually reaches the ocean, where some of it turns into carbon dioxide, intensifying global warming.
‘Unfinished business’: 2 career staffers face rematch in Democrats’ District Clerk runoff
Both incumbent Gloria Martinez and challenger Chris Castillo spent decades at the office before they were pushed out by an old boss.
Eve-of-election hearing set for lawsuit to delay Surfside runoff due to Passover
Judge Lourdes Simon will weigh religious liberty claims against risks of disrupting an election already in motion.
What to expect in Arkansas' primary runoff elections
Two Arkansas Republicans with competing visions on how best to implement President Donald Trump’s agenda to overhaul elections and voting will vie for their party’s nomination for the state’s top elections job on Tuesday.
UK to launch antitrust probe into Microsoft's business software
Britain's competition regulator said on Tuesday it would launch a new investigation into Microsoft's business software ecosystem in May, including its use of software licensing in the cloud market.
Can Iran war politics move voters in Georgia’s Trumpiest district?
The runoff to replace Marjorie Taylor Greene features two military veterans with sharp differences on the joint U.S.-Israeli military strikes in Iran.
AP Decision Notes: What to expect in Arkansas' primary runoff elections
Two Arkansas Republicans with competing visions on how best to implement President Donald Trump’s agenda to overhaul elections and voting will vie for their party’s nomination for the state’s top elections job on Tuesday
AP Decision Notes: What to expect in Arkansas' primary runoff elections
p politics run-off-elections elections | News-Talk 1380 WAOK
'In the absence of any real news, rumours start'
The reason for my new-found, hyper-specific activism is that when there's an international break, particularly at this point in the season, there are still column inches to fill on the clubs that get covered. What I'm saying is won't someone please consider the mental impact on me, personally, of headlines suggesting the entire spine of Newcastle United is going to be sold this summer? If the rumours are to be believed then Sandro Tonali, Tino Livramento, Bruno Guimaraes, Anthony Gordon are the key players eyeing a move, and there could be more.
CPAC activists embrace Paxton as MAGA's choice for Texas Senate over Cornyn
Texas Attorney General Ken Paxton has positioned himself as the grassroots favorite in the runoff election to determine the party’s Senate nominee
MAGA’s eruption has so far kept Trump from endorsing in key Senate race
President Donald Trump seemed set to endorse Sen. John Cornyn in the Texas Republican primary runoff. But strong opposition from MAGA activists forestalled that.
Resident Evil Lore Master Reflects on What Requiem Got Right and Wrong as the Franchise Returned to Raccoon City and 'Retconned' Its Destruction
Resident Evil's unofficial lore master has weighed in with his thoughts on Resident Evil Requiem, which adds a sizable new chapter filled with story revelations to Capcom's veteran horror franchise.
Bringing SaaS to a wellness business
Wellhub CFO Bruno Annicq joined the company for the chance to make a big impact.
This Phillies sports fan knows bad. He says fans have little to complain about
The Parx Casino sports gambling influencer is playing the reverse Uno card on curmudgeonly fans upset about paying steep tix prices.
Derek Sant’Angelo named fellow of the American Association for the Adv
This highly selective honor is in recognition of the VCU professor’s career-long contributions to the field of T cell immunology.
Biotech Company Tivic Health Aims to Advance Immunotherapy Research Programs
Tivic Health Systems is developing immune‑modulating therapies for conditions, such as radiation exposure, while expanding biologics development and manufacturing capabilities.
A mission NASA might kill is still returning fascinating science from Jupiter
We can’t quite afford to support everything that we have done in the past."
Seattle Sports This Week: TV and radio for March 23-29
A look at the broadcast schedule for March 16-22 on Seattle Sports 710 AM and the Seattle Sports app, as well as local sports teams on TV.
Rahm Emanuel proposes banning all federal employees from betting on prediction markets
Socialist Emmanuel Grégoire elected Paris mayor in runoff vote
Emmanuel Grégoire has won the Paris mayoral race and takes over from fellow Socialist Anne Hidalgo. On Sunday, he sealed the moment by riding a city bike to City Hall.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.
Recreation, entertainment top Foy Ranch wish list
By JUNO OGLE Daily Press Staff Outdoor recreation and entertainment were the top two results from a recent survey seeking input on what the city of Bayard could do with the 675 acres of the Foy Ranch it purchased last year — but finding out exactly what that means to people was the object of a public visioning workshop held Tuesday. “Outdoor recreation is kind of a catch-all, and we’d...
Illinois Gov. JB Pritzker to face Republican Darren Bailey as the Democrat seeks a third term
Pritzker won the Democratic nomination unopposed as he gears up for another statewide test before a potential 2028 presidential run.
Thymic health and immunotherapy outcomes in patients with cancer
Nature - A deep-learning approach applied to routine CT scans is used to quantify the health of the thymus in a cohort of patients with cancer, and shows that thymic function is associated with...
No Trump Endorsement for Cornyn or Paxton in Texas Senate Race as Deadline Passes
President Trump’s decision not to weigh in before the deadline means both John Cornyn and Ken Paxton remain on the ballot, extending their costly and increasingly personal battle into a May runoff.
Trump said he wanted one of the Texas Senate candidates to drop out. Now he’s missed the deadline
President Donald Trump promised his endorsement was forthcoming in the GOP Texas Senate runoff and said he wanted whoever he didn’t pick to drop out. But now — preoccupied with the Iran war and a doomed voting bill — he’s missed a critical deadline.
Cue Biopharma Reports Fourth Quarter and Full Year 2025 Financial Results and Business Highlights
Advanced research and development of CUE-401 for IND (Investigational New Drug) readiness –CUE-401 is the Company’s lead asset for the treatment of autoimmune and inflammatory diseasesAppointed industry veteran Lucinda Warren as Chief Financial and Business OfficerRaised net proceeds of $10.2M through an underwritten public offeringAnnounced strategic collaboration and license agreement with ImmunoScape to develop breakthrough cell therapy approach for solid tumors – Entitled to receive upfront
Eagles News: A.J. Brown’s situation remains fluid
Philadelphia Eagles news and links for 3/16/26.
Hay fever: The new wave of effective cures for seasonal allergies
Is it possible to train the body to resist seasonal allergies? That’s the hope promised by a new line of immunotherapy.
The Unoptimized Tensor G5: The Smaller Battery In Samsung Galaxy S26 Lasts 3 Hours Longer Than The One In Pixel 10 Pro XL
Behold the beleaguered battery endurance of Google's Pixel 10 Pro XL vs. Samsung's Galaxy S26 as the unoptimized Tensor G5 takes its proverbial pound of flesh.
'Cater to those who want to express themselves': UNO student balances course work and business ownership
Lydia Okuku's business, Crazy Unicorn, focuses on bright, bold and repurposed pieces.
Have the Giants Been Aggressive Enough in Free Agency?
Though they haven’t made any groundbreaking additions, the New York Giants have been quite active in free agency. The Giants have brought back players like Jermaine Eluemunor and Micah McFadden, while adding newcomers such as Isaiah Likely, Tremaine Edmunds, and Patrick Ricard. But after restructuring and cuts before free agency, there were hopes of retaining more […] The post Have the Giants Been Aggressive Enough in Free Agency? appeared first on The Lead.
Texas Primary Overdrive: Runoffs, Realignments, and Record Turnout
Co-hosts Brandon Rottinghaus and Jeronimo Cortina delve into the latest news in politics
Country music star says he and popular girlfriend have split: ‘Just didn’t work out’
The singer and his influencer ex seem to be on good terms after the breakup.
Lt. Gov. Joe Kelly and Nebraska Business Development Center Recognize 2025 Business Award Winners
Thursday, Lt. Gov. Joe Kelly joined the Nebraska Business Development Center (NBDC) in recognizing recipients of the 2025 Business Awards, honoring entrepreneurs and businesses that are strengthening communities and expanding economic opportunity across the state.
Vaxart Provides Business Update and Reports Full Year 2025 Financial Results
Topline data from 400-person sentinel cohort of the Phase 2b COVID-19 trial anticipated early Q2 2026 Published positive clinical results in the first quarter of 2026 demonstrating oral norovirus vaccine candidate was safe and immunogenic in lactating women and resulted in passive transfer of antibodies to their infants via breast milk Cash, cash equivalents and investments of $63.8 million as of December 31, 2025; Runway into second quarter of 2027 Conference call today at 4:30 p.m. ET Live sto
John Cornyn flips on the filibuster for Trump's SAVE America Act
Cornyn, who spent years defending the filibuster, is locked in a competitive GOP runoff in Texas against Ken Paxton, who has aligned with Trump on the issue.
Live updates: Trump to visit Kentucky; House election in Georgia heads to a runoff
Get the latest news and live updates as Trump visits Kentucky, the election to fill Marjorie Taylor Greene's seat heads to a runoff, and Sen. Cindy Hyde-Smith, R-Miss., is set to face off against Democrat Scott Colom in the fall.
Democrat and Republican head to Georgia runoff election for Marjorie Taylor Greene’s seat
Shawn Harris to face Clay Fuller in special election to replace Marjorie Taylor Greene in Congress
Clayton Fuller and Shawn Harris Advance to Runoff in Marjorie Taylor Greene’s Georgia District
Clayton Fuller will face Shawn Harris, a Democrat, in an April runoff. Mr. Fuller’s win over a flashier Republican showed the power of the president’s support.
Trump-endorsed Republican Clay Fuller to face Democrat Shawn Harris in runoff to replace Marjorie Taylor Greene, CNN projects
Republican Clay Fuller will face Democrat Shawn Harris in a runoff to replace former GOP Rep. Marjorie Taylor Greene in Georgia’s 14th Congressional District, CNN projects.
Artiva Biotherapeutics Reports Full Year 2025 Financial Results and Recent Business Highlights
Initial clinical response data for AlloNK® in refractory rheumatoid arthritis (RA) expected in first half of 2026 U.S. Food and Drug Administration (FDA) interaction to discuss potential pivotal trial design for AlloNK expected in first half of 2026 Strengthened board and executive leadership with deep immunology, commercial and financial expertise Robust balance sheet with cash, cash equivalents and investments of $108.0 million as of December 31, 2025, expected to fund operations into Q2 2027
Georgia votes for successor to Marjorie Taylor Greene after Trump spat
Trump’s pick of former prosecutor Clay Fuller likely to face Democrat and retired general Shawn Harris in runoff for House seat
Dallas Cowboys acquire Green Bay Packers Pro Bowl pass rusher
The NFL’s new league year will unofficially begin this afternoon. Teams will attempt to finalize trades, sign free agents, and make difficult roster cuts before Wednesday’s official start of the league year. The Green Bay Packers had planned to release…
Pokémon Pokopia Physical Edition Price Raised to $80 on Amazon, Amid Reports of Stock Constraints
Amazon has unofficially made Pokémon Pokopia an $80 Nintendo Switch 2 game, after the retailer suddenly increased the price for the new life sim's physical edition amid supply constraints.
2026 NFL free agency live updates: Rumors, news, trade buzz, Monday tracker
It's time for NFL free agency to start – unofficially, of course – as Monday opens the so-called legal tampering period. Follow the moves here.
Artificial Intelligence in Military Medicine: USU Leaders Highlight the Future of Health Education
Panelists at the AMSUS annual meeting discussed how the responsible integration of artificial intelligence will shape the next generation of...
How Kristi Noem's fate was sealed: From the Politics Desk
Plus, Rep. Tony Gonzales faces pressure on Capitol Hill ahead of his runoff.
Noem’s ouster comes as Trump’s Cabinet keeps causing him problems
Donald Trump’s unorthodox Cabinet spent the last 13-plus months testing the wisdom of a president prioritizing loyalty over experience.
The Texas Senate Race Is About to Get Very Ugly
A runoff, resentments, and the question of whether a Democrat can win statewide
Runoffs, voting mishaps and Trump endorsements in TX and NC primaries
The results are in from the first primaries of the midterm election cycle, and Senate races are starting to take shape. We discuss key takeaways from primary contests in North Carolina and Texas.This episode: senior White House correspondent Tamara Keith, political correspondent Ashley Lopez, and senior political editor and correspondent Domenico Montanaro.This podcast was produced by Casey Morell and Bria Suggs, and edited by Rachel Baye.Our executive producer is Muthoni Muturi.Listen to every episode of the NPR Politics Podcast sponsor-free, unlock access to bonus episodes with more from the NPR Politics team, and support public media when you sign up for The NPR Politics Podcast+ at plus.npr.org/politics.
Trump promises to endorse either Cornyn and Paxton – and to push the other to drop out
President Donald Trump announced Wednesday that he would be endorsing in Texas’ Republican primary for US Senate between incumbent John Cornyn and state Attorney General Ken Paxton – and demanding that the candidate he doesn’t choose drop out.
Al Green, Christian Menefee head to runoff in Texas House race
Two sitting Democratic congressmen are duking it out for a redrawn district covering much of the diverse Houston metropolitan area.
Republicans Cornyn and Paxton advance to Texas Senate runoff
Four-term Sen. John Cornyn and his allies spent nearly $70 million to survive the first round of the party’s nomination fight on Tuesday. He was slightly ahead of conservative firebrand Ken Paxton, the state attorney general, with more votes still being counted on Wednesday.
Three Reasons John Cornyn Is Fighting for His Political Life
The veteran Texas senator faces what promises to be a bruising runoff with the state attorney general challenging him from the right. But he had a stronger showing than expected.
Where Trump Appears Vulnerable on the Iran War | WSJ Politics Newsletter for March 4
Plus, Cornyn and Paxton are headed to runoff in their heated Republican Senate primary in Texas as Democrat Talarico beats Crockett
GW Leaders Discuss Sale of Virginia Science and Technology Campus | GW Today | The George Washington University
Executive Vice President, Chief Financial Officer and Treasurer Bruno Fernandes and Interim Provost John Lach address questions about the sale.
Talarico wins Texas Democratic primary as Republicans face runoff
Republican contest in May could provide Democrats with opening to finally win over staunchly red state
Opinion | It’s the Troll vs. the Bore in the G.O.P. Texas Senate Runoff
The state needs intelligent and responsible political leadership, but will it get it?
Talarico Triumphs as G.O.P. Heads to Runoff: 6 Takeaways from Texas
James Talarico won the state’s Democratic primary for Senate, while Senator John Cornyn faces a runoff against Ken Paxton, his right-wing challenger.
Sutton's predictions: Fulham v West Ham
West Ham boss Nuno Espirito Santo was very upbeat about his side's performance at Anfield on Saturday, but they lost 5-2. The only consolation for the Hammers is that the teams immediately above them all lost too. Marco Silva's side played really well in their win against Tottenham on Sunday and Harry Wilson is on fire - my advice is to get him in your fantasy team, now.
Talarico Defeats Crockett in Texas Senate Democratic Primary
In the GOP contest, Sen. John Cornyn and Texas Attorney General Ken Paxton advanced to a runoff in May.