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University, State of Utah sign agreement for proposed south valley health campus
U of U Health has secured land for a proposed health campus that will serve as the health care anchor for the 600-acre master-planned development...
Yearslong Resident Evil mystery solved: Kyle MacLachlan revealed to be Jill Valentine's 'boyfriend'
Twin Peaks star has ties to STARS
Shockwave Medical announces new studies evaluating carotid IVL platform
Carotid artery disease causes up to 30% of all strokes, but severely calcified lesions can make treatment quite complex. The hope is that IVL can be as successful in this area as it has been in the treatment of coronary and peripheral artery disease.
Yankees vs Red Sox: Cam Schlittler vs Connelly Early
The Yankees are back in Boston, but the rivalry is not.
Valve Quietly Walks Back Steam Machine 4K 60 FPS Performance Claims
Valve's Steam Machine has earned more than its fair share of skeptics, thanks to performance claims and more recently its unfortunate pricing. More recently, though, Valve has seemingly taken some of this criticism to heart and silently changed some of those performance claims on the Steam Machine p...
WATCH: Kellyanne Conway insists socialist primary victories don't reflect American values nationwide
Kellyanne Conway says Democratic primary wins reflect only a handful of specific districts and do not signal a broader political shift nationwide.
Making Our Own Luck
We are cross-posting a piece that former NIH official Kris Willis wrote for Macroscience. Kris is now the President and Founder of the Woodley Park Institute, for which I’m a board member. Picking winners or hedging bets? Federal science agencies have long wrestled with the question of how to ensure their billions of dollars of grants and contracts result in maximum benefits for Americans. On the surface, it might seem that a goal-oriented, interventionist style of management would be the best policy: prioritize our most pressing problems and distribute funding accordingly.This top-down strategy creates a unique hazard, though: bad choices can send resources in the wrong direction, resulting in slow progress that impedes the delivery of tangible benefits to citizens. Moreover, if decision makers pursue an applied advance when the underlying scientific principles remain poorly understood, they risk costly failures and a loss of support for the research enterprise at large. Examples include Nixon’s 1971 War on Cancer, undertaken on the premise that a cure could be achieved in less than a decade, the drive to build an operational commercial fusion plant by the mid-1990s, and the National Plan to Address Alzheimer’s Disease, which failed to produce the effective treatments and prevention strategies promised by 2025. The contrasting laissez-faire approach is to hedge your bets. If the path to an advance is impossible to predict, then the wisest choice might be to distribute funding to as widely as possible. The main risk of this strategy is that spreading funding thinly may limit the resources available to the most promising research, resulting in the same negative outcomes as the interventionist approach: limited support for the most promising topics, slow progress, and delayed returns. In reality, at science agencies like the National Science Foundation and National Institutes of Health, program managers navigate between these two extremes, setting some funds aside to target high-priority areas and using the rest to cover the widest possible range of meritorious proposals. This middle path seems like the most rational way to proceed, but it still requires making choices. How much should be set aside for high priority topics? What should those topics be? How should we define merit? Expert opinion can provide a helpful guide, but leading experts can have remarkably different opinions about what matters and what should be prioritized. Moreover, experts and administrators alike can be risk averse, giving an edge to high-profile, well-established concepts. What’s really needed is a data-driven framework to help guide decision-making, one that doesn’t simply repackage prestige or incumbency. Recognizing breakthroughs years in advance Many breakthroughs fail to attract funding or recognition at the earliest stages of development. Katalin Karikó, for example, spent years struggling to win grants for work on mRNA that would eventually win her and Drew Weissman a Nobel Prize. Similar stories can be told about Jim Allison’s groundbreaking studies leading to the development of cancer immunotherapy, Stan Pruisner’s demonstration that prions can self-replicate without DNA, or Robin Warren and Barry Marshall’s proof that Helicobacter pylori, not stress, causes ulcers. Yet at some point, the scientific community recognizes and responds to transformative breakthroughs like these. How does that change happen? And what if science funders could identify the areas that are on the cusp of a breakthrough? Those questions led my collaborators and me to study how scientists responded to past breakthroughs. Based on patterns in that data, we developed a means of predicting future breakthroughs, using biomedicine as a proof of concept. It’s worth taking a moment to describe how our approach works. Briefly, our prediction process begins by grouping the 18 million or so peer-reviewed papers in PubMed, the authoritative database of biomedical research, into roughly 50,000 unique topics. A small subset of these topics are so widely acclaimed as breakthroughs that they have been recognized with a major prize like a Nobel or a Lasker Award. We theorized that studying the development of these outliers over time, especially before they gained acclaim, was the key to identifying future instances of them. After defining topics, we chose 21 representative breakthroughs and asked what they looked like before they won prestigious prizes. To answer that question, we re-ran our topic-mapping algorithm repeatedly, winding back the clock one year each time, stringing together the years to follow the progress of each field as it grew and advanced. We found that in each case, the years leading up to a discovery followed a pattern: a burst of papers on a new, rapidly evolving topic, many of which quickly became influential. These characteristics—the percent of papers that are new, the percentage of papers that are brought in from other topics, and the influence of each individual paper—can all be measured separately for any given topic. Together, they act as a predictive signal that is detectable an average of five years before a transformative discovery is made, and up to thirty years before the discovery receives a major prize. Scanning the current research landscape for topics that display this signal allows us to predict what work will likely produce a future breakthrough. Each year we analyzed includes four or five signals, a number that appears to have remained constant across a twenty year time frame. In their classic work on the sociology of science, Bruno Latour and Steve Woolgar established that the desire to participate in a major discovery is an important motivator for scientists as they consider whether they should take up (or abandon) a research problem. Although further work is needed, the simplest explanation for our results is that this behavior is widespread enough to detect at scale. A foundational advance, or something like it, draws the attention of scientists and causes them to change the direction of their research. They vote with their feet, staking their own reputation and careers by publishing on and citing the new idea. That upswell of interest is the foundation of our breakthrough signal. What kind of research does our model identify as a breakthrough? After building a model based on the patterns in our 21 preselected breakthroughs, we tested it by identifying all early signals of discovery from 1994 through 1997. Of the 18 signals we found in that time period, 17 can be traced forward in time to a breakthrough. Examples include super-resolution fluorescence microscopy (see the image above), the directed evolution of proteins and enzymes (Chemistry Nobel, 2018), and sequencing the human genome (National Medal of Science, 2008). The discovery of the role of leptin signaling in obesity is a particularly interesting case study. Around 1950, scientists noticed the existence of a type of lab mouse that suffered from a unique inherited form of obesity. When given the freedom to choose their own diet, these mice ate more than normal and preferred food that was high in fat. Researchers had few clues as to why the animals overate; early experiments pointed to the existence of a soluble ob factor found circulating in the bloodstream that regulated appetite, but its identity was unknown. In 1994, Jeffrey Friedman and colleagues identified and sequenced the ob gene, noting that the protein it encoded appeared to fit the profile of a circulating factor. A year later, a trio of high-profile publications demonstrated that ob was a hormone that regulated body weight and fat deposition by regulating appetite. One of these was co-authored by Friedman, who christened it leptin from the ancient Greek word for thin. Using our model, the data from 1996 make it clear this advance would become a breakthrough. Scientists had flocked to study the biology of the new hormone, generating the flurry of new papers and citations required to produce a signal. One of these demonstrated that serum leptin concentrations reflected the amount of adipose tissue in the human body, providing clinical validation of the earlier mouse studies. Before the identification of leptin, scientists were unable to point to a specific molecule that controlled appetite and adiposity, so that it was impossible to rule out non-physiological causes of obesity; its characterization fundamentally changed our concept of weight gain. In 2010, Friedman and fellow pioneer Douglas Coleman were awarded a Lasker for the discovery. Our work also identifies breakthroughs in clinical practice and behavioral and social sciences, even though these areas are less likely to draw the attention of major prize committees. One example that falls into this category is the introduction of endovascular aneurysm repair, a minimally invasive surgical procedure for the treatment of abdominal aortic aneurysm, a leading cause of death among Americans over the age of 65. Relative to the previous standard of care, it reduces in-hospital mortality by almost four-fold. In 2017, Timothy Chuter received the American College of Surgeons’ prestigious Jacobsen Innovation award for his multiple refinements to the technique. Another under-recognized breakthrough identified by our model is the development of standardized survey instruments to assess the quality of life for HIV+ patients. The antiretroviral cocktails introduced in the mid-1990s reduced AIDS mortality, but treatment came with serious side effects. The new evaluations showed that patients whose disease progressed had worse physical functioning than Americans with other chronic diseases, while those who were asymptomatic maintained a health-related quality of life on par with the overall US population. This evidence made it possible for patients and activists to argue that even in the absence of a total cure, and in spite of the side effects, alleviation of symptoms was a worthwhile priority for clinicians. My colleagues and I have failed to identify any significant recognition for the physicians and health policy experts who pioneered this advance, although in 2016, researchers called for the World Health Organization to set targets for good health-related quality of life as part of its framework to end the AIDS pandemic. From forecasting to funding How should science funders use our predictions? Any serious discussion of what we should do with this new capability needs to begin with an understanding of its limitations. We can’t (and shouldn’t) invest all of our resources in the small number of topics predicted to produce breakthroughs. Innovative new fields are born from existing ones; they rarely arise de novo. If funders don’t maintain a diverse portfolio, the breakthroughs of tomorrow will have no antecedents. Think of this as eating the seed corn, or killing the goose that lays the golden egg. There are also multiple goals of funding beyond basic scientific discovery, including translating discoveries into clinical practice, developing new technologies, supporting economic development, and training new scientists. The investments needed to accomplish these goals are likely different from those required to support emerging breakthroughs. Finally, we must be aware that we may not capture every instance of a breakthrough. The concept is fuzzy, and not every significant discovery is recognized with a major award. Further, breakthroughs are rare, meaning that our dataset is, by necessity, small. This makes formal estimates of accuracy challenging. Although our overall success rate appears to be high, any one signal may turn out to be a false positive. We found one apparent example: the development of the third generation COX-2 inhibitors, Vioxx and Celebrex, which were much celebrated in the early 2000s as effective but non-addictive pain relievers, meets all the algorithmic criteria of a breakthrough. Five years after it received FDA approval, researchers demonstrated that Vioxx was associated with serious cardiovascular complications, and the manufacturer voluntarily pulled the drug from the market. Celebrex remains available, although like other NSAIDs, it carries an FDA warning for increased cardiovascular risk. Decision makers who were overly focused on the breakthrough potential of this research might have wasted substantial resources nurturing an area that ultimately proved to be a failure—but so would those who relied on expert opinion at the time. That said, the potential benefits of funding the next mRNA vaccine or cancer immunotherapy years earlier than we might have are large. When we can’t assume the outcome of an action, it’s worth conducting an experiment. Can targeted support for areas that are poised to produce a breakthrough increase the return on scientific investment without cannibalizing future advances? With the necessary administrative infrastructure in place, conducting this experiment would be straightforward. First, identify all the breakthrough signals between 2018 and 2023, select half at random, and commit to a decade of investment. For biomedicine, a six year window should yield about 30 topics with the potential to produce a breakthrough. Providing strong support to half of these might be accomplished for $300 million a year. That’s roughly half of the recent annual budget of the NIH Common Fund or around 20% of the fiscal year 2025 budget for ARPA-H. After five years, then again at ten, compare to see which group — the one that was actively managed, or the control — produced more breakthroughs, and on what timescale. Although we used biomedicine as an example, the same experiment could just as well be run for physics, materials science, or any other discipline. Any attempt to undertake such an experiment should keep three points top of mind. First, we can predict the topic of future breakthroughs, but the people and vision for how to move the work forward are still important. In practice, this means success requires active program managers with the expertise to develop the science and the authority to do so, including by recruiting investigators. Second, we would be wise to learn from the failures of past attempts to fund transformative research. High among these are funding modestly repackaged work, confusing the genuinely novel with the merely unfamiliar, and relying too much on incumbent investigators. All of these risks can be mitigated by thoroughly and intelligently integrating high quality data into portfolio management. Finally, we need to have patience. Even with strong funding support, producing a breakthrough takes time. If supporting breakthroughs is the best way to nurture the birth of new fields, we also need to accurately describe and properly manage the other two stages, so that we invest wisely throughout the productive lifetime of ideas and divest once they reach the point of diminishing returns. We would benefit from more study of all of these phases, especially the transition from one to another. More research could answer questions like: When does a breakthrough become an established field? How do the availability of funding, the size and characteristics of the available workforce, and the accumulation of evidence that disagrees with prevailing models affect a field’s decline? Exactly how do old ideas give birth to new ones, and can we speed up the process? The more we understand about the dynamics of scientific progress, the better we can maximize the odds that our curiosity leads to results. I’d call that finding a way to make our own luck.
Blue Jackets acquire Valeri Nichushkin from Avalanche: Sources
Nichushkin, 31, has four years left on his current deal and a 12-team no-trade list.
Valve quietly changes Steam Machine 4K claim: 4K 60 FPS becomes “up to 4K”
Valve has changed the Steam Machine 4K claim. The page now says “up to 4K” with FSR 4.1 instead of 4K 60 FPS with FSR.
Merck KGaA to Acquire Bio-Techne for $11.3B, Expanding Life Science Tools Presence
Merck KGaA, Darmstadt, Germany, has agreed to acquire Bio-Techne for approximately $11.3 billion, the companies said today, in a deal designed to position the buyer as more of a leader across the life science value chain by expanding its presence in high-growth, next-generation life-sci markets with Bio-Techne’s tools, analytical technologies, and consumables.
How Caesars’ Expanded Tribal iGaming and Community Partnership Could Shape Caesars Entertainment (CZR) Investors’ Outlook
In June 2026, Caesars Entertainment Inc. announced that it had expanded its partnership with three Wabanaki Nations in Maine to cover online casino gaming, aiming to launch Caesars Palace Online Casino, Caesars Sportsbook & Casino and Horseshoe Online Casino in 2026, subject to regulatory approval and integrated with Caesars Rewards and a universal digital wallet. A distinctive element of this agreement is Caesars’ commitment to employ and train tribal members while providing financial...
Trump administration identifies more than 500 migrant children for removal from the US, senator says
The Trump administration has identified more than 500 unaccompanied migrant children in US government custody to be potentially removed from the country, according to Democratic Sen. Ron Wyden.
Arts and Entertainment Agenda, June 25 to July 1
Aspen Ideas Festival, June 25-July 1 The Aspen Ideas Festival will run from July 25 through July 1 at the 40-acre Aspen Institute, 1000 N. Third St. The event hosts brilliant minds from around the...
Wilmer Valderrama Launches Social Media Marketing Company
Wilmer Valderrama‘s WV Entertainment has launched a social media marketing company WV Social House.
Myles Garrett's Rise Could Fuel T.J. Watt's Next Steelers Surge
For years, T.J. Watt and Myles Garrett have been linked in one of the NFL's defining player rivalries. Now, with Garrett pulling ahead in recent seasons and Patrick Graham arriving in Pittsburgh, Watt has fresh reasons to respond. For much of their careers, Watt's production far outpaced Garrett's. That changed in 2023 when the Cleveland Browns hired Jim Schwartz as defensive coordinator and Garrett elevated his game to another level.
Health systems must shift AI use from automation to transformation
While healthcare investments in AI are two to three times that of other industries, most providers focus AI's power on tackling administrative tasks. But AI's true value is in transforming care, explain experts at the HIMSS AI in Healthcare Forum.
David P. O'Brien
About five years ago, David P. O'Brien had a comfortable position at Marsh & McLennan Cos., where he held the top post at the financial giant's Louisville, Ky., office. Despite the lofty rank, Mr. O'Brien found himself longing to be at a smaller company that had to work a little harder to land business. That desire led him away from Kentucky five years ago and to Cleveland, where he serves as executive vice president at business insurance agency Oswald Cos. "I left Marsh before it was en vogue," he said, referring to layoffs and defections at Marsh over the course of this year that followed accusations of bid rigging at the big firm. Above all, Mr. O'Brien, 38, wanted to work at a company that relied on its inventiveness, rather than its name, for business. He said he has found that at Oswald. "It causes you to be more creative, to be more resourceful," Mr. O'Brien said. For instance, an Oswald client seeking to do business internationally might be directed to the network of offices abroad run by competitors such as Marsh and Aon Risk Services Inc. "We're going to use whatever access into the market that makes the most sense for our clients," he said. Of course, using such a strategy can be dangerous for Oswald if its client decides to further a business relationship with one of the firms Oswald recommended. "That's the obvious question and why it's nontraditional," he said. "I think if we're good, and if we're bringing value to the client, then there's no risk. I'm not threatened by it." Imaginative business solutions of that type made his career move to Oswald from Marsh worthwhile. "It's very much a challenge," he said. "It helps you keep your edge. I'm all for the competition." John Jacunski, currently vice president and corporate controller at York, Pa., paper company PH Gladfelter Co., met Mr. O'Brien four years ago when Mr. Jacunski was at WCI Steel Inc. in Warren. So impressed was he with Mr. O'Brien's work for WCI that Mr. Jacunski has retained the Oswald executive at PH Gladfelter. "He's a young guy for the position he has, but he's done a great job for us," Mr. Jacunski said. Among his roles at Oswald, Mr. O'Brien leads the firm's client retention efforts and also serves as director of its property and casualty group. "You don't have the same human resources," he said of the job jump to Oswald. "You don't have, obviously, the safety net a big company has." But sometimes, it can be difficult to ascertain individual contributions when working at a big company. "I wanted to be able to see the end results of my work and my efforts," Mr. O'Brien said.
Paranovus Entertainment Technology Limited Announces 1-For-100 Reverse Share Split
NEW YORK, NY / ACCESS Newswire / June 25, 2026 / Paranovus Entertainment Technology Limited (NASDAQ:PAVS) ("we" or the "Company"), today announced that it will effect a reverse share split of its outstanding Class A ordinary shares, par value $0.000012 ...
Ebola response highlights value of African science
With African scientists leading the way in the latest Ebola response, Catherine Kyobutungi makes the case for long-term investment.
How should European scientists respond to the US AI kill switch?
Earlier in June, Europe’s worst fears of technological dependence were confirmed when the White House ordered the AI firm Anthropic to stop non-US citizens using its leading models. This kill-switch moment crystalised anxieties in Brussels that the continent, lagging the US on the creation of leading-edge AI models, is now a technological of vassal of Washington. The shock has specific implications for European scientists and universities. Some governments are now worried that with AI being integrated into labs, Donald Trump now has his finger hovering over an off switch for European science. “Having restrictions on this tool, it can have an impact on our own research,” said France’s research minister, Philippe Baptiste, at the VivaTech conference in Paris on June 18.Baptiste, himself a former academic, said that colleagues in mathematics had recently warned him they were now cut off from leading-edge US models, risking their work. “This model is not available anymore now because of the US restriction, and for the first time this had an impact on mathematics,” a field where large language models (LLMs) are making a significant contribution, said Baptiste. So, should European scientists avoid relying on US models in the future? Or would this be a self-harming overreaction? And how is AI being used in science, anyway? What happened?On June 12, it emerged that Washington, citing cybersecurity concerns, had ordered Anthropic to stop non-US citizens using two models: Claude Mythos 5, and Claude Fable 5, a version of Mythos but with guardrails to prevent abuse. Anthropic said Washington’s concerns were overblown. But forced to follow the order, yet with no way to check who was using the models, the company suddenly shut down access for everyone, US citizens included. There’s still no agreement on how to restore broad access. But last week, Bloomberg reported that select US companies, and the US government, still had access to Mythos despite the ban, but the EU’s cybersecurity agency Enisa had been shut out. Class division of researchersIn the longer term, access outside the US should be restored, said Marcel Salathé, co-director of the AI centre at the Federal Polytechnic School of Lausanne (EPFL), because a permanent restriction would be financially ruinous to US AI firms. “Even Trump will eventually budge to economic pressure,” he said.However, US AI firms might end up operating rather like banks, doing due diligence on users of their leading-edge AI models, he went on.European scientists are unlikely to fall foul of such checks, he said. But having a Chinese postgraduate in their lab, or doing a type of research the US disapproved of, could potentially result in access being denied. “It will create a sort of class division of researchers,” he said. More than frontier modelsHowever, successfully deploying AI in science is about far more than just having access to leading LLMs such as Mythos.Instead, many science-specific tools, most famously Alphafold, which predicts protein folding structures, require “far less” computing power to train than frontier models, well within the capabilities of European supercomputers, according to a recent analysis by the Arq Foundation, a Brussel-based AI think tank. Instead, tools such as Alphafold are possible because certain fields, like protein folding, weather prediction or astronomy, have large, clean, standardised datasets that can be used to train predictive models. Rather than compute, “data is the central constraint for AI for science,” the report says. For example, a less powerful physics model trained on CERN’s data “will be more valuable than the best model without certain data,” said Bengüsu Özcan, author of the report. European advantage?Europe could therefore steal a march by using its scientific data and infrastructure to create models US digital giants cannot. “They might actually match or go even beyond what these big [US] companies are doing,” said Özcan.Indeed, some European start-ups hope to create automated testing labs to create the kind of standardised data that could speed up the discovery of new materials. Materials scientists say there’s currently too little data to train models. AI scientistsHowever, even if the bottleneck for AI in science is often data, rather than compute, being at the mercy of the US for LLM access could still become a problem for European scientists. A new class of “AI scientists” based on leading LLMs is also emerging, Özcan’s report says.Unlike domain-specific tools like Alphafold, these try to automate day-to-day scientific work, by providing an overarching tool that coordinates specific models to synthesise existing literature, generate hypotheses or run analysis of data. The problem for Europe, however, is that these tools are sometimes based on US leading models. Google Deepmind’s AI Co-Scientist, for example, is built on Google’s Gemini LLM. Systematic failureThese scientific automation tools are still in their early stages, and still exhibit “systematic failures on scientific tasks,” Özcan’s report says. One of the problems is that the messy, day-to-day process of scientific discovery is largely not documented, meaning LLMs don’t have a good source of data to learn how scientists actually work. Meanwhile, some tasks, such as literature synthesis, don’t typically require access to leading edge models.However, the performance of AI scientific assistants could improve as companies such as Google pour resources into developing them. Rely on US“Unfortunately, for scientific assistants, there is not much we can do right now except rely on US frontier AI,” said Antoine Bosselut, a natural language processing expert based at EPFL. Chinese-built open models, which can run on local computers, lessening the risk of a shutdown, are touted as one alternative to US dependence. There’s also Mistral, once seen as Europe’s main AI hope, but the Paris-based company has seen its recent models fall behind in performance. But the Chinese alternatives are generally not as capable as US frontier AI models, said Bosselut, unless paired with fiddly, custom tools that allows them to act as independent agents. “Most scientists do not have the time,” he said. Don’t jump ship yetAlthough the kill switch moment is seen a warning shot for European scientists, it doesn’t mean labs should abandon US AI tools immediately. “I do not think the right response is simply to abandon US-based models and systems under the banner of sovereignty or independence,” said Mattias Björnmalm, secretary general of the Cesaer university association. “That would be an overreaction.”Related articlesEuropean sovereignty in AI requires ‘ugly trade-offs,’ say experts Robotic lab start-up makes case for €500M EU-funded materials testing facilityAI in science: is it useful? Instead, European researchers need to ask themselves whether they’re becoming dependent on technology that could be turned off in Washington, said Özcan. “They might not see this today, but they should really start asking this question,” she said. European researchers need a plan B, said Salathé. “I would recommend to every researcher, very proactively explore alternatives.”Own toolsIn addition, Björnmalm and others want European research institutions to develop their own scientific AI tools.Instead of signing AI deals with US digital giants, European universities should be using this money to create their own models, which may end up being superior for research, said Sabine Leonelli, an expert on the use of AI in science at the Technical University of Munich. “Universities in Europe seem to be happy to sign commercial contracts with US companies on the assumption [their AI tools] are better,” she said. But US frontier LLMs are typically opaque, and have been developed without independent scientific input, she said. “This is not good enough for science.”Last year, Swiss researchers released Apertus, an LLM designed to be completely transparent, from its development methods to its training data. The idea is that this makes scientific tools built on top of the model far more reproducible than with closed, commercial alternatives.“Europe needs more of this: serious capacity-building that gives researchers, universities and companies credible options,” said Björnmalm.
Around the MHS
This edition of news from around the Military Health System for the week of June 22-26, 2026, includes a vital partnership between Offutt Air Force Base and the American Red Cross, new Uniformed Services University research on stress fractures, and Naval Medical Research Unit EURAFCENT participates in a multinational readiness exercise.
Experienced Vikings Executive Says Goodbye
The termination of Kwesi Adofo-Mensah in January has led to an avalanche of front office changes in the Twin Cities. […]
KUSTOM ENTERTAINMENT, INC. ANNOUNCES BINDING AGREEMENT FOR THE DIVESTITURE OF ITS VIDEO SOLUTIONS SEGMENT TO FULLY COMPLETE LIVE ENTERTAINMENT PIVOT
Transaction Structured to Provide Up to $5.5 Million plus 2,000,000 Warrants to acquire shares of common stock of Cycurion, Inc.; Follows Previously Announced Major Live Music Expansion Partnership with Gilley’s Park City OVERLAND PARK, KS, June 25, 2026 (GLOBE NEWSWIRE) -- Kustom Entertainment, Inc. (Nasdaq: KUST) (the “Company”), a live entertainment and music festival company, today announced it has entered into a binding agreement for the divestiture of its legacy video solutions division to
Moderna Science Day Highlights Expanding Potential of mRNA Platform
Provides broad overview of Company's research and early development programs expected to continue to fuel future growth Highlights validation of T-cell engager modality with mRNA-2808 in multiple myeloma, supporting rapid advancement of second T-cell ...
Folarin Balogun and USMNT Transfer Updates
Hosts Tamerra Griffin and James McNicholas break down a massive six-match World Cup slate as group stages reach their climax. Soccer insider David Ornstein joins the show to discuss the escalating transfer market buzz surrounding USMNT star Folarin Balogun and Tottenham’s Lucas Bergvall. Plus, the team highlights The Athletic’s interactive World Cup Tracker with Jay Harris to map out the complicated qualification pathways for Group A, B, and C. Can the USMNT line up a favorable Round of 32 matchup? Senior Editor Hannah Vanbiber also dives into the debate surrounding Jeremy Doku’s...
Monterey Motorsports Festival Announces 2026 Entertainment Lineup Headlined by Viral DJ Duo SIDEQUEST
/PRNewswire/ -- The Monterey Motorsports Festival is turning up the volume for Monterey Car Week 2026 with its biggest entertainment lineup to date, featuring...
Commentary: Why Archie Bunker voters are disillusioned with U.S. politics
The 1970s “All in the Family” stalwart supported law-and-order, cultural conservatism and strong labor unions, values to which many Republicans have gravitated, while Democrats evolved into a constituency that adopted identity…
New Media Event Jupiter Festival Planned from Art Basel Company
MCH Group, in which the Fox scion is the largest shareholder, is launching an event titled the Jupiter Festival with an eye toward becoming a stop on the thought leader circuit.
Prosus Investment Values Health Insurer Alan at $6.3 Billion
Prosus—the largest shareholder in Tencent Holdings and owner of food-delivery company Just Eat Takeaway—is investing €400 million in Alan.
The Herald's weekly entertainment picks
Looking to be entertained from Thursday, June 25, through Wednesday, July 1? Check out the Skagit Valley Herald’s weekly recommendations.
Valanciunas described a routine built around constant …
Valanciunas described a routine built around constant …
A season of festivals, special events and America 250 celebrations
The Florida Keys is turning up the heat with summer events this season running from Key Largo to Key West. Think local traditions, world-class culinary festivals, and landmark America 250
Cavaliers named landing spot for ex-$206 million Lakers disaster
The Cleveland Cavaliers were linked to a former Los Angeles Lakers guard who struggled mightily with the franchise years ago.
As Trump kicks off state fair festival, he once again says Iran war is ‘done’
The president made his declaration before a mix of locals and tourists at a scaled-down version of the event after some performers canceled.
Ryman Hospitality Properties says it is evaluating future of Opry Entertainment Group
Ryman Hospitality Properties says it is exploring strategic opportunities for its Opry Entertainment Group.
Former MLB GM Shares Answer To Yankees' Bullpen Woes
The New York Yankees have a clear need in the bullpen, but the team may not have to acquire one through a trade. New York addressed its bullpen at last year's trade deadline, acquiring the likes of David Bednar and Camilo Doval among other relievers. However, Doval has struggled this season, so the ...
Micron and Qualcomm forecasts ignite $400 billion AI chip stock rally
Shares of chipmakers surged late on Wednesday, adding over $400 billion in market value after strong forecasts from Micron Technology and Qualcomm breathed fresh life into Wall Street's recently waning AI stock rally.
Affordable family entertainment coming this weekend at Yuba-Sutter Fair
(FOX40.COM)—The Yuba-Sutter Fair is selling $5 tickets for its opening day on Thursday, and organizers plan to offer a series of ticket discounts throughout the weekend. The fair will run at the Y…
iOS 27 Home App: 10+ New HomeKit Features
Apple updated the Home app with some useful new features that rely on Apple Intelligence. The updates improve the way HomeKit Secure Video cameras work on Apple's HomeKit platform. Apple Intelligence Summaries The Home app generates written summaries for motion alerts and what's detected, using AI to determine what's been recorded.
Healthcare Providers Look Beyond Price To Deliver Better Value
A new approach to procurement promises to not just produce much-needed cost savings but also improve outcomes for patients.
Owner of Grand Ole Opry confirms it may sell country music's most iconic venues
Ryman Hospitality Properties says it is evaluating potential opportunities involving Opry Entertainment Group following recent media reports.
Lancerlot Sports Center holds ice hockey camp for kids, tweens
Kids from around the Roanoke Valley laced up the skates and glided around the ice at Lancerlot Sports Center in Vinton for the VYHA Dogs Camp Wednesday.
Valve clarifies: all Steam Machines, for now, will ship with one 16GB stick of RAM.
In an interview with Gamers Nexus, Valve had said that the PCs would ship with either one 16GB stick of RAM or two 8GB sticks of RAM. “We misspoke here - all units will actually have one 16GB stick of RAM,” the company says in a follow-up statement to the channel. “It’s possible that this might change in future builds, but the units that customers are currently signing up for will all come with one 16GB stick of RAM.” [Media: https://youtu.be/glXA3ObwSwQ?si=QGmDWmVfbMiONxLd&t=109]
Milwaukee County judge weighs in on rising mental health felony cases
Investigative reporting found that mental competency evaluations in felony cases have roughly doubled since 2013, straining resources for the state criminal justice system.
Marquette poll: Few Americans paying close attention to America 250
President Donald Trump’s approval rating stayed the same as May at 38%.
Jasmine Crockett’s silence could hurt James Talarico’s U.S. Senate chances in November
The Dallas congresswoman, Talarico’s erstwhile rival in the Democratic primary, has yet to say whether she’ll campaign for him in the general election against Republican Ken Paxton.
Steam Machine Sells Out in Japan Despite Woeful Pricing
As was the case with the Steam Deck, Valve is selling the Steam Machine via Komodo Station, an Asian reseller that serves much of South-East Asia, and as a result, it skips the reservation and lottery system that is currently in place on Valve's own Steam Store. While this doesn't combat issues like...
A-Rod talks his journey through the 'two B's': Baseball & Business
Former MLB All-Star and A-Rod Corp CEO Alex Rodriguez sits down with Yahoo Finance Executive Editor Brian Sozzi at the 2026 Cannes Lions International Festival of Creativity to discuss his upbringing and personal journeys through baseball and his ventures off the field in the world of business.
Aon Center owner seeks another loan extension as tower’s value plummets
The debt trouble at Chicago’s second-tallest office tower is one of the largest cases of imminent distress downtown amid weakened demand for workspace.
Online violence against women in politics: what shapes political party responses to technology-facilitated gender-based violence?
Political parties have a primary role to play in tackling online violence against women and gender diverse politicians. While the prevalence and impact of TFGBV, such as coordinated disinformation campaigns, deepfake image-based sexual abuse or trolling are well documented, many parties are still building their knowledge on how to respond effectively and have not put in place internal practices and policies that respond to the rapidly evolving, poorly regulated digital ecosystem. About the ReportIn order to promote and protect fair and democratic participation in politics, this ALIGN Report explores what political parties are doing in response to TFGBV and what factors shape their action. The findings, based on existing literature and interviews with gender and politics professionals, indicate there are three sets of factors which donors, civil society and practitioners should consider when designing action to support political parties to respond to TFGBV internally. These are: (1) gender norms; (2) socio-political environment; and (3) internal party factors.Key messagesUnequal gender norms are ubiquitous across politics, shaping expectations of leaders to be strong and assertive, and practices of political parties to uphold masculinist values and sustain cultures of silence. These often lead to weak response to TFGBV against women politicians.The socio-political context can incentivise or disincentivise action, depending on the salience of gender issues, which are increasingly weaponised. Electoral competitiveness, domestic laws (i.e. quota requirements), and even the political system or global normative frameworks influence political will to act.Internal party factors that shape responses will vary across countries and contexts, but include: structures to enforce codes of conduct, policies and reporting mechanisms on (TF)GBV, political ideology, extent of centralisation of leadership, and crucially the meaningful participation of women in decision-making positions, not least through internal women’s wings.Party responses can be seen as a spectrum, with actions falling between active discouragement to address TFGBV to commitment to transform unequal norms and practices within the party.About the ToolkitTogether with the report, this ALIGN toolkit offers gender professionals and others working on democratic strengthening a set of guiding questions and reflection prompts to identify which responses could be most effective and suitable in different contexts. These actions can complement other solutions to TFGBV, such as regulations promoting safety by design. The assessment spans a broad range of factors including: (1) different manifestations of gender norms, (2) the socio-political environment and (3) internal party structures.Key messagesPolitical parties are duty-bound to take action internally to respond to the significant threats posed to women members and candidates, including from their own party colleagues, affiliates and political peers.Existing party approaches to TFGBV can be assessed along a spectrum which ranges from active discouragement and passive acceptance to minimal response and transformative change.To generate effective and context-appropriate solutions to TFGBV, it is important to consider how gender norms shape leadership expectations and internal party practices, while also analysing the impact of the socio-political environment. While actions to support women to stay safe online are very common, codes of conduct and measures to strengthen women’s voice and power in the parties are proposed as most transformative solutions.
Lane County health centers plan cuts to address projected budget deficits
The Community Health Centers of Lane County announced plans to reduce expenses and restructure operations as it works to address projected budget deficits drive
Houston restaurants in East Downtown say business has improved as World Cup continues
The FIFA Fan Festival in East Downtown — where local residents and visitors can watch matches for free — had drawn more than 163,000 visitors as of Tuesday.
Fire at Whiteaker business now being investigated as arson
KVAL CBS 13 is the news, sports and weather source for Eugene, Oregon and nearby communities, including Springfield, Santa Clara, Coburg, Pleasant Hill, Creswell, Churchill, Alvadore, Marcola, Dexter, Thurston, Junction City, Brownsville, Harrisburg, Alvadore, Veneta and Alpine.
QED Science Launches AI Infrastructure for Scientific Validation
Recognizes The 1% After Blind Evaluation of 57,455 Scientific PreprintsTEL AVIV, Israel, June 24, 2026 (GLOBE NEWSWIRE) -- QED Science, a science validity engine and modern infrastructure for researchers, funders, institutions and life science organizations today launched The 1%, the top 574 life science preprints. The company anonymously scored 57,455 bioRxiv preprints submitted between May 2025 and April 2026 for originality and validity. The ranking is powered by QED Score, QED Science’s vali
Walmart buying Vibe.co stirs big buzz at Cannes Lions: analysis
Walmart scored the deal everyone's talking about at Cannes Lions this year. Buying Vibe.co signals its intent to rival Meta, Google, and Amazon.
Program Director Shares How Articulation Agreements Benefit Meredith Pre-health Post-Baccalaureate Students
Karthik Aghoram, director of Meredith’s Pre-health Post-Baccalaureate Program, recently spoke with Inspira Advantage about the program’s articulation agreements and why they are valuable for students seeking careers in health care.
BYD's Stella Li talks expanding the business and home robots (with editor-in-chief Jamie Heller)
Business Insider Editor in Chief Jamie Heller sits down with BYD Executive Stella Li at the 2026 Cannes Lions International Festival of Creativity.
Yankees Rivalry Roundup: Royals drop double-digit runs on Rays
Recapping how the Yankees’ top American League opponents fared on June 23rd.
Joe Manganiello reveals secret health battle, 'live-saving' organ removal
Joe Manganiello details a previously unknown health ordeal that required a "life-saving" organ amputation in his upcoming memoir "Bloodlines."
Darializa Avila Chevalier: pro-Palestinian doctoral student steps into politics with ‘faith in the future’
Mamdani-backed candidate won New York’s 13th congressional district with no experience in office but ideas for how politics can ‘actually invest in life’
House gives final approval to landmark housing bill aimed at lowering costs
The legislation represents one of the most sweeping efforts in decades to increase the supply of housing and bring down prices.
Valve Confirms You Can Build Your Own Steam Machine
Support for NVIDIA hardware is also on the way.
QED Science Launches AI Infrastructure for Scientific Validation
QED Science Recognizes The 1% and Launches AI Infrastructure for Scientific Validation ...
Valve admits Steam Machine is "more expensive" than it hoped
The PC giant is non-commital on whether the console's price will come down in the future if hardware costs reduce
Business is moving past the tech bro era and learning to value ‘real people, real places’
Also: All the news and watercooler chat from Fortune.
Dave And Buster's Entertainment (PLAY) Stock Sees Fair Value Cut After Q1 Analyst Revisions
The fair value estimate for Dave & Buster's Entertainment has been revised from US$18.88 to US$17.00, bringing the price target closer to updated assumptions on comparable sales and earnings. Analysts link this adjustment to a balance of cautious near term expectations after Q1 and ongoing optimism that longer term changes in the business could still support the story if execution improves. Read on to see how this evolving narrative might shape how you track Dave & Buster's Entertainment from...
How New Hampshire Motor Speedway Delivers Maximum Entertainment for the Price
New Hampshire Motor Speedway delivers more than just races — it's an immersive NASCAR weekend featuring multiple race series, live music, fan events and unforgettable atmosphere. Perfect for fans wanting excitement and great value, NHMS provides an action-packed experience that brings motorsports to life at "The Magic Mile."
Diabetes patients in Gaza face survival battle amid war shortages
Insulin and equipment shortages in Gaza pose fatal risks, leading to critical health complications.
Online Entertainment Market
Online Entertainment Market size is expected to be worth around USD 2,058.30 Billion by 2035 from USD 604.7 Billion in 2025, at a CAGR of 13.30%
Chevalier celebrates projected New York primary win
Democratic candidate Darializa Avila Chevalier celebrated her projected win in the Democratic primary in New York's 13th District after defeating incumbent Rep. Adriano Espaillat. Chevalier was joined by New York Mayor Zohran Mamdani who she was endorsed by.
Playing the Moon Game
Apollo astronauts previewed their roles as lunar field geologists in Alaska’s Valley of Ten Thousand Smokes.
Mamdani-backed socialist candidate storms out of live interview when confronted with old social media posts
Darializa Avila Chevalier walked out of a radio interview after being pressed about controversial social media posts in her NY primary race.
Darializa Avila Chevalier wins NY-13 Democratic primary, AP says
The district comprises parts of Upper Manhattan, including Harlem and Inwood, and parts of the Bronx, including Kingsbridge Heights.
Claire Valdez wins NY-7 Democratic primary, Spectrum News says
Valdez, who is part of the Democratic Socialists of America, was elected to the state Assembly in 2024.
Valdez is Democrats' pick in New York House race in a win for democratic socialists
Assembly Member Claire Valdez, a democratic socialist state lawmaker, won a competitive Democratic primary for a safely blue New York City-based House seat.
Early humans were bringing fire into caves 1.8 million years ago
A new study suggests early humans were using fire in South Africa’s Wonderwerk Cave as far back as 1.79 million years ago. Researchers found burned bones deep inside the cave, where natural wildfires could not have reached, indicating that fire was likely carried in and maintained by human ancestors. The discovery pushes back the timeline for fire use and reveals surprisingly sophisticated behavior long before humans could create fire on demand.
Oracle Backend for Microservices and AI: The Business Value of a Microservices Backend Platform
Discover how Oracle Backend for Microservices and AI (OBaaS) 2.1.0 provides a shared backend foundation for microservices and AI-enabled applications, helping teams standardize gateways, observability, messaging, configuration, workflow coordination, and Oracle AI Database integration.
House gives final approval to bipartisan housing bill aimed at lowering costs
Lawmakers in both parties are eager to show progress on affordability issues ahead of this year’s midterm elections
Biden judge overruled on key Trump immigration policy
Federal appeals court revives Trump administration's nationwide expedited removal policy, allowing fast-track deportations of eligible illegal immigrants.
Kansas Democratic gubernatorial candidate's union membership sparks political finger-pointing
Democratic candidate Cindy Holscher's membership in the KNEA union raises an alarm in union-endorsed rival Ethan Corson's campaign for governor.
Lincoln County Fair offers week of family entertainment
STANFORD, Ky. — From rodeo action and demolition derbies to monster trucks and fireworks, organizers say this year’s Lincoln County Fair will offer something for nearly everyone while continuing a […]
Google Pixel phones get better wireless audio quality in Android 17
While wired audio is certainly trying to make a comeback, wireless earbuds and headphones are more prevalent today than ever...
'True Blood' star Joe Manganiello shares secret multi-year health battle, organ removal
Manganiello is detailing his journey in his memoir, "Bloodlines," out October 13.
Steam Machine is 'more expensive' than even Valve wanted it to be
The PC gaming giant knows some fans won't be able to afford its new system, but Valve didn't want things to work out this way
Roku May Help Fox Avoid Aggregeddon
(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Scrolling through links over the last week, I stumbled across this fun headline: Wow. Formula 1 (the sport, not the docu-series) is the perfect “dog not barking”. As a reminder, each week in my Streaming Ratings Report, I call out the shows that miss every viewership chart. I dub them “dogs not barking”—like the Sherlock Holmes mystery—because without any data, we forget they even exist. This is in contrast to something like, say, a film flop—cough The Mandalorian and Grogu cough—where even underperforming at the box office is widely discussed here, there and everywhere. In the US, Formula 1 is now in “no public viewership data, so not discussed” territory. After moving to Apple TV from its former home of ESPN, basically no one talks about it. Apple did publish an initial, unsourced, unsubstantiated, (dare I say unserious) datecdote claiming more folks are watching Formula 1 on Apple than ESPN, but we haven’t gotten any updates since. This stands in contrast to when the sport streamed on ESPN, and ESPN PR provided weekly viewership figures. Formula 1 was, at best, a niche sport in America—averaging 1.3 million viewers in the Big Data Plus era—but now it’s basically anonymous. (And yeah, after moving to Apple, I very, very, very much doubt its ratings increased.) Unfortunately, that story isn’t quite big enough to warrant a section in today’s “Most Important Story of the Week” column, but I wanted to call it out, because otherwise, no one else will! Certainly, no one will write articles about the silence/ratings decline, unlike when they wrote breathless articles connecting the rise in viewership to Netflix’s Drive to Survive, including Reuters just last month. (This is a topic I’ve tried to provide a moderate/nuanced/non-hyped take since 2022.) Anyway, on to this week’s issue. I was a bit worried I didn’t have a juicy topic, then the Murdochs went out and did their Murdoch thing: buying Roku. So that’s the story of the week, and it happens to touch on quite a few themes of the streaming wars and the disruption therein. I’ll cover that, plus why more consolidation in Hollywood media looks likely, more good news on the Hollywood labor front, whether we’ll see an uptick in production in Los Angeles, some Broadway and theme park news, cellphone prices going up in the third world (and possibly everywhere), and more. Subscribe Most Important Story of the Week - Another Big Media & Entertainment Merger The story of the week is clearly Fox is buying Roku for $22 billion. I read a lot of good strategy takes on why Fox bought this streaming TV device maker—and I’ll have mine below—but what fascinates me more is how this deal connects to quite a few themes of the streaming wars, linking to everything from the pace of M&A to “aggregeddon” to Netflix’s recent M&A actions/inactions to the shift to advertising from pure play streaming and more. The only topic I can’t really connect it to is my old theory, “never bet against Rupert Murdoch” because he isn’t the one who did this deal; his son Lachlan inked it. (Do I think he provided advice, even at his 95 years of age? Sure.) That plus I have one additional piece of strategy for all entertainment players, inspired by this deal. So let’s dive into all those topics, starting with why I like this deal. Roku is a Great M&A Buy
‘Not Easy Bein' Green' – These pop icons rival Reflecting Pool color
Look beyond Lincoln Memorial’s Reflecting Pool to see green icons from pop culture like Kermit, Yoda and Shrek.
Pre-RAMpocalypse Steam Machine Pricing was ~30% Cheaper
It's no secret that Valve's Steam Machine is launching at possibly the worst moment for both PC and console gaming hardware, given the ongoing DRAM crisis, but Valve engineer, Pierre-Loup Griffais, has recently shed light on the pre-RAM crisis pricing of the Steam Machine, revealing that it was neve...
Cannes Lions Feels More Hollywood Than the Film Festival This Year
With creators increasingly at the center of entertainment, the fest built on brand marketers is gaining even more weight now ("I've never seen anything like it," one attendee notes).
What early Cannes Lions conversations reveal about AI, creators and agencies
After my first day at Cannes Lions, two things stood out immediately: the festival feels busier than it did a year ago, and the mood feels more optimistic.
What they're saying about five frontcourt Warriors prospects in 2026 NBA Draft
Here are some pros and cons of five frontcourt players the Golden State Warriors have evaluated ahead of the 2026 NBA Draft.
Two women are at the center of New York’s next big political test
Mayor Zohran Mamdani has backed democratic socialist candidates Darializa Avila Chevalier and Assembly Member Claire Valdez.
Yankees Rivalry Roundup: Royals’ Wacha outduels Rays’ Rasmussen
Recapping how the Yankees’ top AL opponents fared on June 22nd.
Valve Explains Why You Have To Pay $1,050 To $1,430 For A Steam Machine
Valve has finally revealed the price of the Steam Machine, and it's more than almost anyone predicted. Can you afford it?
Smart drones, safe skies: Student’s system tests, coordinates drone fleets
Doctoral student’s project devises an autonomous airspace coordination system built around a real-time simulation and validation technology.
SCCSD Board approves purchase of school supplies & science curriculum
The South Conway County School District will once again be providing school supplies for all students in grades K-12 in the 2026-27 school year. The purchase of over $40,000 in supplies from the Arch Ford Education Service Cooperative is among the approvals granted by the […]
Apple's Foldable iPhone Could Lose Almost $1,300 in Value in First Year, Study Suggests
A new resale value study suggests that a $2,000 foldable iPhone could lose as much as $1,292 of its value within its first 12 months on the market, based on current foldable depreciation trends. The estimate comes from SellCell, which analyzed the 12-month resale performance of flagship smartphones from Apple, Samsung, Google, Motorola, and OnePlus.
Cannes Lions International Festival of Creativity announces winners across the Entertainment and Craft Track Lions
Cannes Lions International Festival of Creativity announces winners across the Entertainment and Craft Track Lions
Cadence raises $100 million to automate chronic disease care with regulated AI
Digital health startup Cadence has raised $100 million at a $1.23 billion valuation to expand its chronic disease management program.
Farage says £5m gift spending details 'not public's business'
Rival parties have raised concerns over the gift received by the Reform UK leader before he became an MP.