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Immunic COO highlights the importance of science-led innovation to mark World Health Day
Immunic Inc (NASDAQ:IMUX, FRA:10VA) chief operating officer Jason Tardio talked with Proactive's Stephen Gunnion about the importance of science-led innovation in tackling neurological diseases, particularly multiple sclerosis, on World Health Day 2026. Tardio highlighted that the biotech industry is fundamentally grounded in scientific research and data, noting that “everything we do is rooted in science.” He explained that Immunic is focused on developing innovative therapies designed to improve patient outcomes and address significant unmet medical needs. The discussion centred on multiple sclerosis (MS), a complex neurological disease that continues to present challenges despite decades of progress. Tardio pointed out that while advancements have been made, “the disease is not solved for,” with many patients still experiencing disability progression and requiring safer, more tolerable treatments. He emphasised the urgent need for innovation, particularly in progressive forms of MS where treatment options remain extremely limited. Immunic’s lead asset, vidofludimus calcium, is being developed as a novel approach aimed at addressing the full spectrum of the disease. Tardio also reinforced the broader mission of the healthcare and biotech sectors, stating that the ultimate goal is to help individuals “live a better quality of life” and “a healthier life longer.” Watch the full interview to learn more about Immunic’s approach to advancing MS treatment through science. For more videos like this, visit Proactive's YouTube channel, like this video, subscribe to the channel, and enable notifications so you never miss an update. #Immunic #MultipleSclerosis #BiotechInnovation #Healthcare #MSResearch #DrugDevelopment #ClinicalTrials #Neurology #WorldHealthDay #ScienceDriven #VidofludimusCalcium #PharmaNews #BiotechNews
Inside Huntington’s growing music & entertainment scene
Within the past decade, Huntington has drastically improved its music and entertainment scene. Growth of live music locales like The Loud, 9th Street Live and summer concert series provide exposure and experience to local artists. This change has opened new doors for Huntington musicians, especially Marshall students looking to launch a music career. One live...
Updated Iowa women's basketball scholarship allocations
After the transfer portal entrances of Teagan Mallegni and Emely Rodriguez, what does Iowa women's basketball's scholarship allocation look like?
11 years later, Obsidian's Pillars of Eternity gets a turn-based combat mode to make it a little bit more like Baldur's Gate 3
Obsidian Entertainment has just updated fantasy RPG Pillars of Eternity with optional turn-based combat more than 11 years after launch.
Google Adds Mental Health Tools to Gemini Chatbot After Lawsuit
Alphabet Inc.’s Google plans to introduce new mental health support features for its Gemini chatbot as the company and rivals, like OpenAI, have faced several lawsuits accusing their artificial intelligence tools of leading to harm.
Google Adds Mental Health Tools to Gemini Chatbot After Lawsuit
Alphabet Inc.’s Google plans to introduce new mental health support features for its Gemini chatbot as the company and rivals, like OpenAI, have faced several lawsuits accusing their artificial intelligence tools of leading to harm.
MAGA Is Winning Its War Against U.S. Science
Source: NBER With all the other terrible news right now, you may not have noticed that Donald Trump is in the process of killing American science. OK, that’s an exaggeration — but not that much of an exaggeration. The Trump administration’s latest budget proposal calls for a gigantic increase in military spending combined with severe cuts to social programs. But as the chart above shows, it also calls for debilitating reductions in research funding. Furthermore, Trump appointees have already been strangling science by sharply reducing the rate at which research grants are approved. Here, for example, is the number of new grants approved by the National Science Foundation: Source: Nature Large numbers of existing grants have also been frozen or terminated, especially in the study of infectious diseases. Add to this a sharp drop in visas issued to foreign students, who often play a direct role in research and who help support academic departments that do research: Put all of this together, and much U.S. scientific research is set to come to a screeching halt — not a few years from now, but over the course of the next year or two. This new assault on U.S. science is taking place at a time when the role of American science in the world has already been greatly eroded. The chart below, based on research recently reported by the National Bureau of Economic Research, measures national strength in science by the share of publications in highly ranked journals. In the 1990s the United States had more such publications than the rest of the world combined. Since then we’ve dropped into third place — well behind China and slightly below the European Union. And this was before the Trump administration’s attack on science had time to take its full effect. Source Some erosion in U.S. scientific preeminence was inevitable given China’s growing sophistication and wealth. But we’ve also fallen behind Europe, even though everyone says that Europe is lagging economically and technologically. Claims about Europe’s underperformance are, in fact, dubious if one looks hard at the data. But it’s still striking to see America lagging. What’s going on? There are presumably multiple factors behind America’s scientific lag. But even before Trump II the growing hostility of the U.S. right to science surely had some negative effect. And since the rise of MAGA G.O.P. attitudes toward science in general have become overwhelmingly hostile. This is true even for the Republican rank and file: And while I haven’t been able to find good survey data, it’s obvious that the anti-science turn has been even more pronounced — and began earlier — among the Republican political elite. Chris Mooney published The Republican War on Science in 2005, and even then was describing a longstanding trend. Why have Republicans turned so anti-science? Part of the answer is that they believe that scientists don’t support them. And they’re right! A study of who scientists give money to shows that only a small percentage gave money to Republicans even 20 years ago, and that almost none of them donate to Republicans now: Social scientists have always been strongly pro-Democratic, while there used to be a significant number of physical, “hard” scientists supporting the GOP. But these days physicists are almost as uniformly Democratic, or at least non-Republican, as sociologists. Why are there almost no Republican scientists? It’s not a mystery. GOP political orthodoxy includes positions that are at odds with the scientific consensus on multiple issues, ranging from the validity of the theory of evolution, to the reality of climate change, to the efficacy and safety of vaccines. In each case the scientific consensus is solidly grounded in evidence. But even before the rise of MAGA the U.S. right was increasingly hostile to evidence-based policymaking — especially, of course, where the evidence is unfavorable to fossil fuel interests or quack medicine, both financial mainstays of right-wing politics. So scientists don’t support Republicans, and the feeling is mutual. Today’s Republican Party doesn’t like science or scientists. It doesn’t like having its preconceived views challenged by appeals to evidence. It knows that very few scientists are on its side electorally. In general, it sees scientific research as a threat to its grasp on political power. Add in MAGA’s combination of rabid anti-intellectualism and allergy to any hint of criticism, and one has the makings of a drastic anti-science turn in policy. “Ignorance is strength” might was well be an official MAGA motto. And as I said, we aren’t talking about something that will happen over the course of multiple years: The U.S. scientific enterprise is threatened with severe damage, even collapse, over just the next year. There are many reasons to find this prospect horrifying: Think of all the beneficial advances, affecting almost every part of life, that won’t happen because U.S. science — still crucial to the world — has been eviscerated. But think, also, of America’s international standing. Can a nation that has forfeited its role as a leader, or even a contender, in global science, still be a Great Power? No. MUSICAL CODA
Bourbon demand is down and tariffs aren't helping. But distillers keep building.
Like many whiskey distillers, Heaven Hill Brands is rolling back bourbon production this year, as demand lags. Yet, as the American spirit faced a tumultuous market in 2025, the Kentucky company built a new, $200 million distillery in the heart of bourbon country, adding 155,000 barrels of capacity.
Fernando Mendoza partnership to bring financial education to NFL players
The 2026 NFL draft's likely No. 1 overall pick, Fernando Mendoza, is partnering with U.S. Bank to educate players about business and finance.
‘This is what consolidation looks like’: Eliott Rodriguez reports $312K raised in 21 days for CD 27
The longtime Miami anchor is posting strong early numbers as Democrats jockey to challenge María Elvira Salazar.
Apple’s 2026 Shake-Up: iPhone 18 Pro Leaks While iPhone Fold Steals The Show
Which iPhone flagship should you be waiting for? This September’s launches will be unlike any previous year.
Dricus Du Plessis reveals his favorite fighters
Everyone has favorite fighters they like to watch, or that they relate to for whatever reason. Former UFC middleweight champion Dricus Du Plessis is no different. During a recent fan question and answer session, Du Plessis was asked which fighters he admired and why. "Stillknocks" listed mostly ...
Finding Trends in Sports Stats and ‘Wheel of Fortune’ Puzzles
Ben Blatt, a data reporter for The Upshot, dreams up inventive ways to answer questions like: “Is Taylor Swift actually increasing N.F.L. ratings?”
Yet again, when rights are in conflict
I admit, it is going to take quite a bit of self-control to not have this entire column end up being yet another screed about a certain president who continues to shock the world in his race to the bottom of intellectual discourse. Like many, I suspect, when I first read the social media post […]
The Michigan Wolverines won a title by mastering college basketball’s new world. It might change the sport
Michigan, a team that has performed like a freight train in this NCAA tournament, won the national title – the Big Ten’s first in 26 years – by playing more like a bulldozer.
Red lights are flashing on the scarcity of oil
Six weeks ago, the world was practically swimming in crude oil. The market was oversupplied and prices were low and stable. But now, some parts of the energy market are acting like the world is on the verge of running dry.
Overwatch Reveals The Anran Redesign Fans Begged For
The character looked more like Kiriko and Juno than her brother Wuyang
Google has launched a free, offline AI dictation app that will automatically polish your speech.
Google AI Edge Eloquent is a new live AI transcription app that requires no subscription and has no usage limits. When you finish speaking, it will also filter out filler words like “um.” It’s currently only on iOS, but Google plans to bring the app to Android and macOS. [Image: https://platform.theverge.com/wp-content/uploads/sites/2/2026/04/google-ai-edge-eloquent-app-store.jpg?quality=90&strip=all]
Drew Barrymore and Amanda Peet once made out at one of Carrie Fisher's house parties: 'Life used to be so much more fun'
"I feel like Matthew Perry was there?" Barrymore recalled.
3 Things to Know: Brands and Social Issues, Adult Recreational Sports League Participation Rebounds, and Sports Betting Partnerships
CivicScience has the world’s largest proprietary database of real-time declared intent, allowing brands to activate high-performing advertising that drives up to 80% better performance. See how our partners achieve superior marketing outcomes here. 1. Consumers hold mixed expectations on brand activism, with Democrats more likely to switch or boycott based on personal values, while Republicans [...]Read More... from 3 Things to Know: Brands and Social Issues, Adult Recreational Sports League Participation Rebounds, and Sports Betting Partnerships
FBI warns against foreign mobile apps like CapCut in new PSA
A new public service announcement from the FBI is warning Americans about apps based in China.
Google quietly releases an offline-first AI dictation app on iOS
Google's new offline-first dictation app uses Gemma AI models to take on the apps like Wispr Flow.
From Jurassic Park to dreams of AI doom, pop culture shapes science more than we like to admit
We all know science influences books, movies and TV – but the influence goes both ways.
Executive Order would put restrictions on student-athletes ability to transfer, limit eligibility
The introduction of Name, Image and Likeness deals and the transfer portal has opened a new frontier for college sports.
Teardown of unreleased LG Rollable shows why rollable phones aren't a thing
LG almost released a rollable smartphone in 2021, and this is what it looked like inside.
Clemson business students land elite finance programs, build path to Wall Street
Through Clemson’s emphasis on mentorship, hands-on learning and professional development, Ava Hester and Morgan Harvey have earned spots in prestigious programs like Girls Who Invest and the Wharton School’s Fundamentals of Corporate Finance and Valuation program.
What OpenAI’s TBPN deal reveals about branded entertainment’s limits
Brands like OpenAI are building in-house entertainment studios on the promise that great content earns the audiences advertising can’t buy.
How fuel surcharges are squeezing small business margins
Rising fuel costs are hitting small businesses with a new wave of shipping expenses, as major carriers pass along higher diesel prices through surcharges many owners say feel like “tariffs 2.0,” The Wall Street Journal writes. FedEx and UPS have pushed fuel surcharges above 26%, while diesel prices have surged sharply in recent weeks, driving […]
Steve Bannon wins Supreme Court order likely to lead to dismissal of contempt of Congress conviction
Longtime Trump ally Steve Bannon has won a Supreme Court order that’s expected to lead to the dismissal of his criminal conviction for refusing to testify to Congress
‘Crimson Desert’ Has A Quest You Should Save Rollback To Avoid
Crimson Desert has a lot of quests, but there is one that you should avoid like the plague.
National parks that feel like another world, from frequent US traveler
I've visited all 63 major US national parks and think places like Bryce Canyon, Death Valley, White Sands, and Badlands feel like another planet.
Travel blogger’s new book offers ‘52 Weekends in the Pacific Northwest’
Kara Patajo, also known as Your Northwestie Bestie online, treats every day in the Pacific Northwest like an adventure.
A New Era of Sports Broadcasting: Galaxy S26 Ultra Unlocks New Perspectives, Bringing Cameras Inside the A ...
Capturing new angles like never before, Galaxy S26 Ultra’s broadcast-ready capture transforms how skateboarding is filmed, experienced and delivered in real time
Beauty’s New Challenger Conglomerate Has Always Been Here
By shedding its food and ice cream businesses, Unilever is betting big on beauty. But matching the scale, valuation and category depth of rivals like L’Oréal and The Estée Lauder Companies will require sharper focus and strategic discipline.
Scientists found a “lost world” of animals that shouldn’t exist yet
A remarkable fossil discovery in southwest China is rewriting the story of how complex animal life began, showing that many key animal groups appeared millions of years earlier than scientists once believed. Dating back over 540 million years, the fossils reveal a surprisingly diverse and advanced ecosystem from the late Ediacaran period—before the famous Cambrian explosion. Among the finds are early relatives of starfish, worm-like creatures, and even ancestors of animals with backbones, suggesting that the roots of modern life were already taking shape.
The brain might not create consciousness after all
Is consciousness something the brain produces, or is it woven into the fabric of reality itself? Renowned neuroscientist Christof Koch is challenging long-held scientific assumptions by confronting the “hard problem” of consciousness — why and how subjective experience exists at all. He highlights growing tensions between neuroscience, physics, and unexplained phenomena like near-death experiences and sudden moments of clarity before death.
Scientists may have found a way to keep your bones strong for life
Scientists have identified a little-known receptor, GPR133, as a powerful regulator of bone strength. By activating it with a newly discovered compound called AP503, they were able to boost bone density in mice and counteract osteoporosis-like damage. The finding opens the door to a new kind of treatment that could not only prevent bone loss but also rebuild weakened bones, offering fresh hope for millions affected by osteoporosis, especially aging populations.
Scientists may finally detect hidden ripples in spacetime
Scientists have taken a major step toward probing one of physics’ biggest mysteries—how gravity and quantum mechanics fit together—by creating the first unified way to detect tiny “ripples” in spacetime itself. These subtle fluctuations, long predicted but poorly defined, are now organized into clear categories with specific signals that real-world instruments can search for. The breakthrough means powerful tools like LIGO and even small tabletop experiments could start testing competing theories of quantum gravity much sooner than expected.
Facing Michigan’s ‘Monstars,’ UConn finds itself in the unlikely position of underdog
UConn is one of the most storied programs in college basketball. They’re facing a test in Michigan unlike anything they’ve seen in years.
Survey: Has an AI agent interviewed you for a job?
Some employers are tapping the tech to act as a human recruiter. If you've been in the hot seat, Business Insider would like to hear from you.
State Of Decay 3's Announcement Trailer Wasn't Actually The Game
The trailer also featured things that won't be in the full game, like zombie deer.
In New Orleans' French Quarter, Easter is a destination event for LGBTQ community and locals
There’s only one place in the world where you’re as likely to find drag queens parading through town on horse-drawn carriages on Easter Sunday as you are to find kids on the hunt for eggs and processions of locals headed to church for Mass.
What impact is the science of reading having so far in Ohio classrooms and on college campuses?
The science of reading is being taught in classrooms across Ohio, but the state's education department stresses it will likely take time to track students' progress.
St. John's Health 'likely' to ask voters for property tax bump
As St. John’s Health navigates turbulent financial waters and a potential Wyoming property tax cut at the ballot in November, the hospital may ask Teton County voters to double its
Stop pasting this into AI — 7 things you should never share with a chatbot
AI tools aren’t designed to store sensitive information like private documents or bank details — so don’t treat them like a safe
On plant health and embracing new plant-breeding techniques in South Africa
The major challenge currently confronting South Africa’s agriculture is the spread of foot-and-mouth disease. For many farmers across the country, the most urgent tasks are both securing sufficient vaccines and rolling them out quickly in the coming months, particularly as the beef and dairy industries continue to suffer big losses. There is also pressure on sheep, goats, and other livestock to prevent the disease from spreading. As efforts to get the country through this monumental challenge continue, I believe it is important to sharpen our focus on the broader task at hand: strengthening biosecurity. This covers both animal and plant health. In recent years, we haven’t focused much on plant health, except a few times, such as when we had a goss’s wilt scare in the maize industry, a few cases of citrus black spot, or cases of sclerotinia in sunflower seeds. But the fact that South Africa managed to control the outbreaks of these particular diseases when they occurred a few years ago was due to organized agricultural and government scientific capabilities, and, most importantly, the availability of crop protection or agrochemicals necessary to address some of them. Therefore, as the animal health division in the Department of Agriculture focuses on the pressing challenge of the day, the foot-and-mouth disease, there is an opportunity for the plant health division to assess if they have all the requirements to tackle any outbreak that may occur on fruits, vegetables or crops in future. The challenge with crop diseases is that they can spread quickly and cause much more rapid damage in the field than we typically see with livestock. Therefore, speed is everything in ensuring the appropriate controls are available. I raise this as an important area, particularly given the drastic climate variation we observe across the country. The production conditions in some areas have changed noticeably over time, which may introduce new risks. The other essential part is ensuring that South Africa has access to the best crop protection technology available in the market. Many technology developers worldwide have operations in South Africa. Therefore, the Department of Agriculture, along with the Agricultural Research Council, must continuously interact with technology developers to assess the various crop protection technologies they are releasing globally and determine their suitability and need in South Africa. This will require a proactive approach from the government, unlike the current approach, in which technology developers typically approach regulators with new technologies. The government, recognising the food security risks, must take a proactive approach to ensure that South African farmers have access to the latest crop protection technologies, thereby safeguarding the country’s food security. Beyond crop protection, we must never forget that South Africa’s agriculture is key to ensuring that the country is the most food-secure country at the national level in sub-Saharan Africa. South Africa is also the only African country in the top-40 global agricultural exporters, having more than doubled since 1994 on the back of the adoption of high-yielding seed cultivars. South Africa has been the only African country to adopt a bold approach to embracing science and adopting genetically engineered seeds for grains and oilseeds in the early 2000s. Since then, we have seen crop yields improve noticeably, contributing to the gains we mentioned above. But ensuring that South Africa improves further is not a given. The key lies in South African regulators’ attitudes towards new technologies. We have to maintain a progressive approach and not give in to the politics of non-food and non-scientific voices that shout on the sidelines. Food security is national security, and the government must ensure we progress, leaning on science. Therefore, the registration of high-yielding new genomic techniques is required. South Africa cannot afford to fall behind the EU, the USA, South America, and many of its competitors in global agriculture. The Department of Agriculture’s crop science division must adopt a progress-and-science-embracing approach for the good of the country. Thanks for reading AgriView! Subscribe for free to receive new posts and support my work. Subscribe Share
No Time to Read, Plenty to Say
In an era where information is increasingly packaged as entertainment and consumed rapidly, the transmission of meaning has become more fragile. Writers, technologists, and institutions alike are realizing that communication is a complex interaction shaped by audience habits, digital tools, and shifting cultural norms. Each alteration not only affects what we know but also how we understand. The result is a growing tension between expression and interpretation. One that challenges our assumptions about knowledge, attention, and responsibility in the modern world.
UF Dance Marathon raises over $1.1 million for UF Health Shands Children’s Hospital
Behind the lights and energy of the University of Florida’s Dance Marathon, stories like that of Amelia Early and her daughter, Dani-Lynn, took center stage.
NVIDIA's DLSS 5 trailer has been taken down due to 'copyright' infringement
NVIDIA's DLSS 5 announcement trailer is currently offline on YouTube due to a copyright infringement claim from an unlikely source.
Warriors' Draymond Green reveals 'ideal' outcome for upcoming free agency
It remains to be seen what the future holds from Draymond Green beyond the current campaign, but the veteran forward has an idea of how he would like it to go. Green recently laid out his “ideal” scenario for his NBA future, which would entail him declining his $27 million player option for the 2026-27 season in favor of a new extension to close out his career in Golden State. “Rich [Paul] and I discussed it a couple months ago briefly,” Green said.
Trump news at a glance: president accused of ‘threatening possible war crimes’ in Iran post
Chuck Schumer accuses president of ‘ranting like unhinged madman’ in threat to obliterate Iran’s power plants and bridges. Key US politics stories from 5 April
‘American Pickers’: Mike Wolfe Is Awestruck Meeting Disney Movie ‘Cars’ Designer
He was like a kid in a candy store.
‘American Pickers’: Mike Wolfe Is Awestruck Meeting Disney Movie ‘Cars’ Designer
He was like a kid in a candy store.
AI breakthrough cuts energy use by 100x while boosting accuracy
AI is consuming staggering amounts of energy—already over 10% of U.S. electricity—and the demand is only accelerating. Now, researchers have unveiled a radically more efficient approach that could slash AI energy use by up to 100× while actually improving accuracy. By combining neural networks with human-like symbolic reasoning, their system helps robots think more logically instead of relying on brute-force trial and error.
I quit Brown after a year to launch my own venture capital firm at 21.
Smaiyl Makyshov started a VC firm at 21 to invest in young founders, and those from accelerator communities like Y Combinator and A16z's Speedrun.
Science Fiction as Prior Art?
Some inventors find their inventive spark through science fiction. Tasers, for example, were inspired by (and named after) the 1911 novel Tom Swift and His Electric Rifle. Likewise, Motorola’s...
Elementary Science Olympiad exposes Alabama students to high-level science competition
Nearly 250 elementary students gathered at Auburn University for the Elementary Science Olympiad, a day of hands-on competition and discovery. Through fast-paced challenges and collaborative problem-solving, students experienced what it means to think and work like scientists.
How to ‘detox’ your body for free without juice, teas or flushes
Feel like your body needs a reset? What if we told you that you can ‘detox’ for free by leveraging your body’s natural waste removal systems. PolitiFact shares how to do some spring cleaning without paying for a “juice cleanse” or “detox diet.”
What did Pompeii smell like before it burned?
Ash from Roman incense burners indicate families burned tree resins from thousands of miles away.
Study of 1,700 languages reveals surprising hidden patterns
A massive new analysis of over 1,700 languages shows that some long-debated “universal” grammar rules are actually real. By using cutting-edge evolutionary methods, researchers found that languages tend to evolve in predictable ways rather than randomly. Key patterns—like word order and grammatical structure—keep reappearing across the globe. The results suggest shared human thinking and communication pressures shape how all languages develop.
Mark Cuban: Health care billing ‘should look like 1955.’ Why he thinks insurance companies rip off hospitals
“Our health care has become a game of who can rip off who and get away with it.”
4 Clever Uses For The Thunderbolt Port On Your PC
Many modern laptops and PCs now support Thunderbolt, which looks like a regular USB-C port but can support high-speed external drives, eGPUs, and more.
New Orleans’ Giant Puppet Festival brings eclectic performances to the Marigny this weekend
“I feel like I have seen a lot of puppet shows, and I am always surprised when I come to the festival."
What the Muppets can teach us about Maine politics
For dreamers like me, the Rainbow Connection seems distant. Our political climate has abandoned what I consider the Muppet spirit: a celebration of wistfulness, a collective made strong by diversity and humble and transparent leadership. Contemporary politics has been like shadow puppets: projections designed to obscure the causes of our dysfunctional society. The Muppets offer […]
What the Muppets can teach us about Maine politics
For dreamers like me, the Rainbow Connection seems distant. Our political climate has abandoned what I consider the Muppet spirit: a celebration of wistfulness, a collective made strong by diversity and humble and transparent leadership. Contemporary politics has been like shadow puppets: projections designed to obscure the causes of our dysfunctional society. The Muppets offer […]
Celebrity impersonation looks like good business
The impersonation industry is about more than just the man who lived at Graceland—it’s thousands of other people pretending to be celebrities for money.
Celebrity impersonation looks like good business
The impersonation industry is about more than just the man who lived at Graceland—it’s thousands of other people pretending to be celebrities for money.
How to measure bad smells: the citizen science that is challenging the stench of rotten eggs and cabbage soup
The growing public awareness of odor pollution in countries like Spain clashes with the lack of regulation
4 Takeaways From the NCAA Men's Basketball Tournament Final Four
From UConn's status as a modern-day dynasty to Michigan looking like a team of destiny, here are four takeaways from the NCAA Men's Basketball Tournament Final Four.
Mars dust storms are sparking electricity and rewriting the planet’s chemistry
Mars may look like a quiet, dusty world, but it’s actually buzzing with hidden electrical activity. Powerful dust storms and swirling dust devils generate static electricity strong enough to spark faint glowing discharges across the planet, triggering chemical reactions that reshape its surface and atmosphere. Scientists have now shown that these tiny lightning-like events can create a surprising mix of chemicals—including chlorine compounds and carbonates—and even leave behind distinct isotopic “fingerprints.”
5 Gadgets You Can Plug Into Your TV's HDMI 2.0 Port
Discover the best gadgets to plug into your TV's HDMI 2.0 port. We detail top devices like streaming sticks, sync boxes, and gaming consoles.
Fossil site in China reveals bevy of complex creatures lived prior to the Cambrian explosion, including a 'Dune'-like sandworm
A site in southwestern China holds a wide array of strange life-forms that emerged prior to the Cambrian explosion, and it pushes back the origin of complex life by millions of years.
Astros New Approach Is Sustainable
For the first couple of games, the Astros offense looked like it was trying to force everything. The swings came early, the contact was weak, and too many innings ended before the opposing starter ever felt uncomfortable. It had that familiar early-season look of a lineup still searching for rhythm. But the last few games […]
Why Spring Cleaning Is Good for Your Home AND Your Health
While spring cleaning might feel like just another thing on your to-do list, it can actually do more for your health than you might expect.
Album Review: 6WA by BigXthaPlug & 600 Entertainment
BigXthaPlug spent eight months in Nashville making a country-rap album that debuted at No. 7 on the Billboard 200, put “All the Way” with Bailey Zimmerman at No. 4 on the Hot 100, got him a Rolling Stone cover, and filled arenas with Jelly Roll. And then he came back to Dallas, rounded up four of his signees, and made a gangsta-rap record with N.W.A’s Straight Outta Compton on the cover. 6WA is the second group release from 600 Entertainment, named after the 600 block of Meadowridge Street in Ferris, Texas, where BigX and his people grew up. The whole thing is loaded with West Coast samples. From N.W.A.’s “8Ball,” Eazy-E’s “Real Muthaphuckkin G’s” and “Boyz-N-The-Hood,” Ice-T’s “6 in the Mornin’,” Snoop Dogg’s “Nuthin’ but a ‘G’ Thang” and more. BigX is staking his name on the lineup he built—Rosama, MurdaGang PB, Yung Hood, KevanGotBandz, KaineMusic—and claiming a lineage from 1,400 miles away while insisting Dallas is its own thing. A million dollars in cash, split and handed straight to his mother. That’s the first place BigX goes on “From the Bottom.” He’d probably still be in the streets if he didn’t have his son and daughter. He only started rapping to make life better for Carter. Couldn’t start his car back then, now people get starstruck at Starbucks, and he throws the whole field away in one sentence: “How you think we competin’? You on the same bag, I just made me some millions off country.” Goyard bags off a Nashville payday, and he wants you to know exactly how far he’s come from everybody else. “Safe to Say” does something similar but looser. It’s a straight Ice Cube “It Was a Good Day” flip, and BigX nails it. Wakes up, checks both phones, nobody’s locked up, kid accounts look good. Gets pulled over, only catches a warning. Pulls up on the squad to liquor, ladies, and haze. Rosama takes the second verse and matches him. Wakes up to his girl cleaning his cuticles, twins playing peekaboo, pays off his car, calls a cousin, sees the opps and they don’t trip. Lawyer calls, he beat his case. Rosama is the strongest voice in the 600 camp after BigX, and “Life of a Gangster” is why. Third person, riding low, blacked-out windows, snub-nose revolver. A character who chose sticking people up over selling dope. “Quick eraser like a number-two pencil.” He never breaks character, and his delivery drops lower and slower than anything he does on the group cuts, like he’s telling you something at a cookout that he probably shouldn’t. Then on “Long Live Fre$h” he’s a completely different rapper. “Short-bus diamonds, these bitches retarded,” wide-body Durango he can’t even park. That kind of range matters on a group record. MurdaGang PB’s best verse is on the title track. Feds at his door at 6 AM, cameras busted, flushing dope, ram truck putting everybody on the floor. Yung Hood on “The Hottest” just lays out four reasons to keep hustling. Who wants to be broke, women cost money, you need bail, and home has to be straight. It’s funnier and more honest than most rappers get when they’re trying to explain why they sell drugs. KevanGotBandz on “Ain’t Never Slowin’ Down” talks about his father getting caught on the dope while he’s sitting on $300K somewhere in the hills, which is a specific kind of guilt that doesn’t usually make it onto crew tapes. KaineMusic, the newest signee, takes the back half of “Who Dunnit” and introduces herself in third person—“Took flight just to show these hoes how to perform”—but it’s too short to know if she can hold a full song. The flex tracks fill the middle of the LP and mostly run together. “I Go” is Rosama and PB trading brands, guns, and food punchlines. Rosama’s “anemic, my iron tucked low in this shirt” is a slick gun bar, PB fires back with “.223 with a clip ‘bout as big as a toddler” and “I go Burger King, stay with that whopper.” Quick, funny sometimes, but it’s all shopping lists. “Dopeman” is a chant. “6ixer Party” brings Snoop Dogg, who does exactly what you’d expect Snoop Dogg to do. BigX contributes the night’s wildest overshare: “She say she brought a friend too, well, I’m tryna put sausage on her dental.” These songs move fast and don’t overstay, but three or four of them could trade verses and nobody would catch it. Midway through, The D.O.C. shows up for a spoken-word interlude. Tracy Curry. West Dallas native, former N.W.A affiliate, co-writer on a lot of the records getting sampled on this very album. He thanks BigX for the tribute and then gets direct: “This your time, this DFW time. You need to do it like we do it down here.” Leave bread crumbs so everybody behind you can eat. Keep God in your life. It’s fatherly and generous, and it does raise the question of whether 6WA follows that advice. The album borrows heavy. The cover art, the Eazy-E samples, “Amerikkka’s Most Wanted” opening with a direct “Boyz-N-The-Hood” lift, Yung Hood rapping “Flag on my left side, Crip until I die.” But the stuff that actually stays with you is Dallas. BigX talking about Pleasant Grove, Rosama calling himself a country boy, PB recounting a raid that could’ve been last Tuesday. The record smells most like itself when it smells like Ferris, Texas, and least like Compton. BigX on “The Hottest” says his father was the first person he knew who had chickens. Not the way rappers usually wave at the drug trade. He means his actual father, his actual family. On “600 Degrees,” Rosama compares his chopper’s stutter to a speech disorder, PB claims he still has the block on his back even after leaving the city. BigX closes that one saying he used to spin and smack, and now the plaques are platinum. Thirty-two minutes was right for this. Nobody overstays, Tony Coles and Rance and Charley Cooks keep the production punchy, and BigX gives his signees real room instead of crowding every song. 6WA doesn’t reinvent anything. Five rappers, good beats, short clock. Most of what they say you’ve heard before. Some of it—the million to his mother, the cuticles and peekaboo, the four reasons to hustle—you won’t forget. Solid (★★★½☆) Favorite Track(s): “Safe to Say,” “From the Bottom,” “The Hottest” Subscribe
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Agentic AI, OpenClaw, and everything brewing in that space is going to spur mass experimentation in open models to complement the likes of Claude and Codex, not replace them. Especially with open models, the benchmarks at release are an extremely incomplete story. In some ways this is exciting, as new open models have a much higher variance and ability to surprise, but it also points at some structural reasons that make building businesses and great AI experiences around open models harder than the closed alternatives. When a new Claude Opus or GPT drops, spending a few hours with them in my agentic workflows is genuinely a good vibe test. For open models, putting them through this test is a category error. Something else to be said about open models in the era of agents is that they get out of the debate of integration, harnesses, and tools and let us see close to the ground on what exactly is the ability of just a model. Of course, we can’t test some things like search abilities without some tool, but being able to measure exactly the pace of progress of the model alone is a welcome simplification to a systematically opaque AI space. Share The list of factors I’d use to assess a new open-weight model I’m considering investing in includes: Model performance (and size) — how this model performs on benchmarks I care about and how it compares to other models of a similar size. Country of origin — some businesses care deeply about provenance, and if a model was built in China or not. Model license — if a model needs legal approval for use, uptake will be slower at mid-sized and large companies. Tooling at release — many models release with half-broken, or at least substantially slower, implementations in popular software like vLLM, Transformers, SGLANG, etc due to pushing the envelope of architectures or tools. Model fine-tunability — how easy or hard it is to modify the given model to your use-case when you actually try and use it. The core problem is that some of these are immediately available at release, e.g. general performance, license, origin, etc. but others such as tooling take day(s) to week(s) to stabilize, and others are open research questions — with no group systematically monitoring fine-tunability. In the early era of open models, the days of Llama 2 or 3 and Qwen pre v3.5, the architectures were fairly simple and the models tended to work out of the box. Some of this was due to the extremely hard work of the Llama, Qwen, Mistral, etc. developer teams. Some is due to the new models being genuinely harder to work with. When it comes to something like Qwen 3.5 or Nemotron 3, with hybrid models (either gated delta net or mamba layers), the tooling is very rough at release. Things you would expect to “just work” often don’t. I’ve been following this area closely since we released Olmo Hybrid with a similar architecture, and Qwen 3.5 is just starting to work well in the various open-source tools that need to all play nice together for RL research. That’s 1.5 months after the release date! This is just to start really investing more into understanding the behavior of the models. Of course, others started working on these models sooner by investing more engineering resources or relying on partially closed software. The fully open and distributed ecosystem takes a long time to get going on some new models. All of this is lead-in for the most important question for open models — how easy is it to adapt to specific use-cases? This is a different problem for different model sizes. Large MoE open-weight models may be used by entities like Cursor who need complex capabilities in their domain, e.g. Composer 2 trained on Kimi K2.5. Other applications can be built on much smaller models, such as Chroma’s Context-1 model for agentic search, built on GPT-OSS 20B. The question of “which models are fine-tunable” is largely background knowledge known by engineers across the industry. There should be a thriving research area here to support the open ecosystem model. The first step is to understand characteristics of different base and post-trained models to understand what they look like. The second step is to tune pretraining recipes for open models so they’re more flexible. Interconnects AI is a reader-supported publication. Consider becoming a subscriber. Subscribe For The ATOM Project and other Interconnects endeavors, we’ve put in substantial effort to measuring adoption trends in the open ecosystem. Everything takes a long time to unfold after a model is first publicly available — and adaptability is why. What we know for sure now, when Qwen has been going from strength to strength with its releases, is that technical staff across the industry has gotten comfortable working with Qwen models. Countless research methods and datasets were made to work with Qwen. It’ll take patience for any other model family to get to this point — a patience I’m not sure many open model builders have. This takes us to Gemma 4, Google’s latest open models. Gemma 3 was released more than a year ago, in March of 2025, and is a bit underrated. Gemma 4 comes in 4 sizes for now, with a bigger, MoE model of over 100B total parameters rumored but not released yet. The models we have today come in sizes of ~5B dense, 8B dense, 26B total 4B active MoE, and 31B dense. I’m most excited that they’re finally adopting a standard Apache 2.0 open source license. This’ll massively boost adoption. The standard of better licenses for strong open-weight LLMs was set by mostly Chinese open model labs in the last 1-2 years, and now U.S. companies are following suit. I will personally be so happy if the horrible Llama licenses and Gemma terms of service were an ~18-month transient dynamic of the industry being nervous about releasing strong open models. The Gemma 4 scores look very solid, the small models have incredible benchmark scores (especially in general domains like LMArena) and the 31B model rivals the recent Qwen 3.5 27B, which is the leading member of that class. The ~30B size range is an important one, as it’s accessible both to researchers and to enterprises looking to deploy the model in real use-cases. Where the 7B model scale is the default for tinkering and research, a 30B model is the default for seeing if an open model can unlock substantial value in your specific workflow — a good mix of intelligence, low price, tractability for downstream training, etc. This takes us back to the above adoption criteria I mentioned for open models and the bigger question — do I think Gemma 4 will be an overwhelming success? Previous Gemma models have been plagued by tooling issues and poorer performance when being finetuned. Gemma 4’s success is going to be entirely determined by ease of use, to a point where a 5-10% swing on benchmarks wouldn’t matter at all. It’s strong enough, small enough, with the right license, and from the U.S., so many companies are going to slot it in. I’m cautiously optimistic that Gemma 4 is going to work better here. Winds are shifting for open models built in America. We saw GPT-OSS go through a bumpy launch to become an overwhelming success. There’s a collective energy around the likes of Reflection, Arcee, Nemotron, Gemma, Olmo, and peers that show substantial demand for building new stacks around open models. There’s capital to be spent on AI stacks across the economy by those who want more ownership of everything, including the model. After launching The ATOM Project 240 days ago, the conversation is shifting into the next stage. Summer of 2025 was a crisis moment where the U.S. AI scene realized it can’t wait and figure out open models after building AGI. The two markets will capture different areas and proceed in parallel. Now that more companies in the U.S. are releasing strong models, we need to improve the ecosystem so that these models are easy to use, understand, and build value around. It’s the hard work to build another inflection point in these adoption plots I’ve been updating consistently, but that’s the work to be done. Join me in it. More data coming soon! Here’s a sneak peek:
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