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Winners and losers from first weekend of the NCAA tournament feature John Calipari, Darryn Peterson, Big Ten and blue bloods
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Mar 23 • 2:04 AM EDT • Sports • sports.yahoo.com
NCAA women's tournament takeaways, Day 3: Minnesota drains buzzer-beater as LSU, Texas dominate again
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Mar 23 • 1:01 AM EDT • Sports • sports.yahoo.com
St. Louis Blues Weekly Prospect Report (March 22)

Jiricek has big scoring week; McIsaac announces future plans; Ralph, Michigan State head to NCAA Tournament with Mayich, Clarkson University eliminated; Peterson scored pair, including a SH beauty for Springfield

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Mar 23 • 12:54 AM EDT • Sports • sports.yahoo.com
NCAA tournament takeaways, Day 4: Big Ten's March Madness domination continues with 6 league teams making Sweet 16
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Mar 23 • 12:24 AM EDT • Sports • sports.yahoo.com
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NCAA, NIT, WBIT tournaments lead to uptick in business for Wichita bars

Fans of KU, K-State and WSU flocked to sports bars to cheer on their favorite teams.

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Mar 23 • 12:17 AM EDT • Business • kwch.com
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A DNA test ruled him out. He was convicted of murder anyway.

Forensics has its share of high-profile problems. There’s phony “junk science,” like bogus bite-mark and blood spatter analyses that have sent innocent people to jail. And there’s the steady drumbeat of lab scandals, where analysts make up results. But there’s a subtler and more pervasive problem at work in many cases: lab analysts and lawyers who take perfectly legitimate science and twist it. Globe Opinion is exploring these distortions with a series we’re calling “Twisted Science.” And there may be no better place to start than with the case of Terrel Barros.

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Mar 22 • 9:57 PM EDT • Science • bostonglobe.com
Florida basketball stunned by Iowa in March Madness Round 2 upset

Florida basketball was stunned by Iowa, ending its hopes to repeat as national champions in the Men's NCAA Tourrnament.

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Mar 22 • 9:34 PM EDT • Sports • usatoday.com
Kansas coach Bill Self unsure about future after buzzer-beater loss to St. John's: 'I haven't decided'

After a heartbreaking last-second loss in the second round of the NCAA tournament, Self wasn't ready to discuss his coaching future.

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Mar 22 • 8:39 PM EDT • Sports • sports.yahoo.com
Alabama vs. Texas Tech odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Texas Tech vs. Alabama picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 8:03 PM EDT • Sports • cbssports.com
Students compete in Virginia Science Olympiad State Tournament at UVA

The tournament’s events ranged from knowledge tests to building robots.

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Mar 22 • 6:22 PM EDT • Science • 29news.com
Students compete in Virginia Science Olympiad State Tournament at UVA

The tournament’s events ranged from knowledge tests to building robots.

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Mar 22 • 6:22 PM EDT • Science • whsv.com
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Women's March Madness live updates, scores: LSU makes history in NCAA tournament; Minnesota stuns Ole Miss to advance to Sweet 16
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Mar 22 • 5:19 PM EDT • Sports • sports.yahoo.com
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The OG Four-Door Porsche Sports Sedan Wasn't Even Built By Porsche

In 1967, a Texas-based car dealer wanted a four-door Porsche 911 S. Porsche wouldn't make it, so he turned to coachbuilders for help.

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Mar 22 • 3:05 PM EDT • Technology • jalopnik.com
Your Thymus and Your Healthspan

Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.

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Mar 22 • 2:18 PM EDT • Health • erictopol.substack.com
Syracuse finalizing Gerry McNamara hire: Siena coach helped lead Orange to 2003 national championship

McNamara just finished guiding Siena to the NCAA Tournament, where it almost upset No. 1 Duke

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Mar 22 • 2:15 PM EDT • Sports • cbssports.com
Syracuse reportedly targeting former player Gerry McNamara as its next men's basketball coach
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Mar 22 • 1:52 PM EDT • Sports • sports.yahoo.com
Southern Living names top small towns, Florida snags 5 spots

St. Augustine named best small town in the Southern United States.

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Mar 22 • 1:46 PM EDT • Politics • floridapolitics.com
Kentucky vs. Iowa State odds, time, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Kentucky vs. Iowa State picks for the NCAA Tournament 2026 second-round game on Sunday

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Mar 22 • 1:03 PM EDT • Sports • cbssports.com
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2026 NCAA Men's Basketball Tournament Highlights: Round of 32 Continues

The 2026 NCAA Men’s Basketball Tournament continues with the Round of 32 on Sunday, and we've got you covered with all the highlights!

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Mar 22 • 12:03 PM EDT • Sports • foxsports.com
Assemblywoman Alexandra Macedo says César Chávez allegations are "just the tip of the iceberg"

California lawmakers this upcoming week are set to move quickly to rename César Chávez Day to Farmworkers Day ahead of the holiday that takes place every year on March 31.

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Mar 22 • 11:25 AM EDT • Politics • kcra.com
PICROSS S KONAMI ANTIQUES edition announced for Switch

Jupiter has announced PICROSS S KONAMI ANTIQUES edition for Switch. It will launch via Nintendo eShop on April 30 for $17.99 / €17.99 / £16.19 / ¥1,800.

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Mar 22 • 11:01 AM EDT • Technology • gematsu.com
Oscar-Winning Alumnus Returns to Pasadena’s ArtCenter for Entertainment Design Expo

One week after winning the Academy Award for Best Animated Feature, KPop Demon Hunters co-director Chris Appelhans returns today to ArtCenter College of Design, the Pasadena campus where he studied illustration, for the college’s third annual Entertainment Design Expo. The expo, known as ENTX, opens the Hillside Campus to the public for a full day of gallery exhibitions, game playtesting, animation screenings and interactive experiences featuring work from more than 200 ArtCenter students and alumni. General admission is free with advance registration. Two industry panels — including Appelhans’s talk — require $15 tickets. Appelhans, who graduated from ArtCenter with a bachelor of fine arts in 2002, co-directed KPop Demon Hunters with Maggie Kang. The animated film, produced by Sony Pictures Animation and released on Netflix, became the streaming platform’s most-watched film in history, according to Netflix, and swept awards season with wins at the Golden Globes, the Annie Awards and the Grammys before taking the Oscar on March 15. His talk and audience Q&A is scheduled from noon to 1 p.m. in the Ahmanson Auditorium. Doors open at 11:30 a.m. The film’s ArtCenter ties extend beyond its co-director. Art director Angela Sung, cinematographer Gary H. Lee, visual development artist Celine Kim and painter Simon Baek are all ArtCenter graduates who worked on the production, according to the college. The free portions of ENTX include a concept design showcase, a production design gallery, a model gallery, a stop motion studio preview, an alumni gallery and a KPop Demon Hunters fan art gallery. Visitors can also playtest games designed by ArtCenter students. An Animation Shorts Showcase runs from 2 to 3 p.m. and includes “Boy, I’m Scared,” a capstone short by ArtCenter graduate Lindsey Tenaglia that was named a semifinalist for the 2025 Student Academy Awards in the animation category. Also screening

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Mar 22 • 8:30 AM EDT • Entertainment • pasadenanow.com
“Let’s get ourselves back to Fort Worth, but take care of business at hand,” LSU after loss in Tulsa

LSU Gymnastics’ Sophomore Kailin Chio and Head Coach Jay Clark spoke to the media following a third place finish in the 2026 SEC tournament in Tulsa, Oklahoma. Tiger fans came into the BOK Center hopeful for a victory due to having a podium setup, which LSU seems to have thrived on in the past. Which...

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Mar 22 • 7:41 AM EDT • Business • lsureveille.com
Dynamax Regice Max Monday: Event Guide

Max Monday features a different Pokémon in power spots for the whole day. Regice Max Monday takes place on March 23rd, 2026. This Max Monday is the fourth March Pokémon, and it is the debut of the legendary Ice Pokémon Dynamax Regice! Dynamax Regice is a Tier 5 Max Battle in Pokémon GO. It will cost […]

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Mar 22 • 6:11 AM EDT • Technology • pokemongohub.net
White House navigates vaccine politics, midterm risks in CDC director search

The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.

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Mar 22 • 6:00 AM EDT • Health • washingtonpost.com
White House navigates vaccine politics, midterm risks in CDC director search

The Trump administration faces complicated political dynamics as it seeks someone to helm the key public health agency suffering a prolonged leadership vacuum.

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Mar 22 • 6:00 AM EDT • Politics • washingtonpost.com
Scouting Future Saints: Washington wide receiver Denzel Boston

Denzel Boston might not be the most popular name among receivers in the draft, but he's among the most talented and he could fit what the Saints need.

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Mar 22 • 5:55 AM EDT • Sports • sports.yahoo.com
Andrej Karpathy says he uses an AI agent to control his pool

Andrej Karpathy said an AI agent named Dobby texts him whenever he gets a Fedex package and helps him control his spa.

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Mar 22 • 5:09 AM EDT • Technology • businessinsider.com
Duke vs Baylor predictions, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Duke vs No. 6 Baylor in the 2026 women's NCAA Tournament on March 22

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Mar 22 • 5:08 AM EDT • Sports • usatoday.com
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Where to watch Minnesota vs. Ole Miss in March Madness Second Round: Time, TV Channel

The No. 4 Minnesota Golden Gophers face the 5 Ole Miss Rebels in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Duke vs. Baylor in March Madness Second Round: Time, TV Channel

The No. 3 Duke Blue Devils face the 6 Baylor Bears in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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Where to watch Oklahoma vs. Michigan State in March Madness Second Round: Time, TV Channel

The No. 4 Oklahoma Sooners face the 5 Michigan State Spartans in the Second Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 22 • 5:06 AM EDT • Sports • usatoday.com
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What time is Michigan women's basketball's second round game?

Michigan cruised to a blowout victory over Holy Cross in their opening NCAA Women's Tournament matchup. See who they play next.

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Mar 22 • 4:46 AM EDT • Sports • sports.yahoo.com
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A Grip on Sports: In a season when Gonzaga's defense was the driving force behind its success, the Zags couldn't get the one stop they needed

A GRIP ON SPORTS • After all the flotsam and jetsam is swept away, sometimes a college basketball game, an NCAA Tournament game, comes down to making one play. Saturday night in Portland, Texas did. And Gonzaga’s season once again fell short of its ultimate goal.

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Mar 22 • 3:16 AM EDT • Sports • spokesman.com
OPEN THREAD

The Daily Merengue is a place where you can feel free to discuss all things football. Do not be alarmed by the overt RMCF bias. It’s in the name! Shoutout to the mods who do a fantastic job Kung_Fu_Zizou, Juninho, NeRObutBlanco, Felipejack, Ezek Ix and yours truly, Valyrian Steel. Gameday!! Huge clash in the context […]

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Mar 22 • 2:39 AM EDT • Sports • sports.yahoo.com
2025-26 Women's Second Round Odds: Spreads, Lines for all 16 Games

Check out the odds for all 16 games of the women's NCAA Tournament Round of 32.

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Mar 22 • 1:52 AM EDT • Sports • foxsports.com
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NCAA tournament takeaways, Day 3: Big Ten reigns supreme, 'Cinderella' Texas and an extra edge for Houston
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Mar 22 • 12:44 AM EDT • Sports • sports.yahoo.com
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Nebraska survives near-miracle heave at buzzer to advance past Vanderbilt in thriller, keep dream season alive

Nebraska and Vanderbilt put on a show in one of the best games of the NCAA tournament.

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Mar 21 • 11:18 PM EDT • Sports • sports.yahoo.com
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Another Illinois basketball player enters legendary status in NCAA tournament

The Illinois basketball team has had some incredible performances this season, and one player just put up an amazing Round of 32 showing against VCU.

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Mar 21 • 11:08 PM EDT • Sports • sports.yahoo.com
Digimon Story: Time Stranger large-scale expansion DLC announced

Publisher Bandai Namco and developer Media.Vision have announced a large-scale expansion downloadable content for Digimon Story: Time Stranger. It will launch in 2027.

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Mar 21 • 10:52 PM EDT • Technology • gematsu.com
5 incredible observations from the Illinois basketball win over VCU

Illinois basketball continued their trek in the NCAA tournament with a huge win over VCU on Saturday night.

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Mar 21 • 10:35 PM EDT • Sports • ca.sports.yahoo.com
Former OSU athletes talk mental health at Scioto County Mindset Matters Summit

Big names like former Ohio State Point Guard Scoonie Penn, Heisman Trophy winner Troy Smith, former Buckeye Bobby Carpenter, taking the stage at the event to talk with our very own Joseph Payton about mental health.

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Mar 21 • 10:15 PM EDT • Health • wsaz.com
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No. 11 Texas becomes 6th First Four team to make NCAA tournament's Sweet 16 with upset win over No. 3 Gonzaga
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Mar 21 • 9:40 PM EDT • Sports • sports.yahoo.com
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Coaches in elite company clash when Kansas faces St. John's

SAN DIEGO -- Only three active head coaches in Division I college basketball have won multiple national championships. Two of them meet for a berth in the Sweet 16 when Bill Self's No. 4 Kansas Jayhawks face Rick Pitino's No. 5 St. John's Red Storm on Sunday in the second round of the NCAA Tournament East Region.

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Mar 21 • 9:01 PM EDT • Sports • cbssports.com
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Business investment in the era of digital transformation

The weak performance of business investment across the OECD since the Global Financial Crisis holds back potential growth. However, it masks a strong investment dynamic in digital assets such as hardware, software, and databases. This column describes how this divergence between digital and non-digital assets has intensified from the mid-2010s. The strong investment performance of the US relative to the rest of the OECD is almost exclusively a digital phenomenon. A ‘digital divide’ is emerging, where laggard countries are accumulating digital capital per worker more slowly than those with higher initial starting levels.

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Mar 21 • 8:00 PM EDT • Business • cepr.org
‘They want to colonise us’: Brazil’s Lula warns of foreign interference

The left-wing Brazilian president is critical of US actions throughout Latin America, though he does not name Trump.

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Mar 21 • 7:35 PM EDT • Politics • aljazeera.com
Four takeaways from Nebraska men’s basketball’s NCAA Tournament win over Vanderbilt

OKLAHOMA CITY – Braden Frager. Learn the name.

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Mar 21 • 7:11 PM EDT • Sports • dailynebraskan.com
Politics Unplugged (Full Episode) March 22, 2026

This week on Politics Unplugged, Progressive activist Kai Newkirk explains why he is running to unseat Democratic incumbent Greg Stanton in the congressional race in CD4. Then, consultants Marcus Dell’Artino and Matt Grodsky discuss the fallout from the Cesar Chavez allegations and the political importance of high gas prices.

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Mar 21 • 6:29 PM EDT • Politics • azfamily.com
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Stephen Curry nears return for Warriors, but will miss at least 2 more games as regular season winds down

Stephen Curry will have 10 games to play at most before the start of the play-in tournament.

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Mar 21 • 5:45 PM EDT • Sports • sports.yahoo.com
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Donald Trump Is Nothing Like Robert Mueller

The absurdity of a man who avoided Vietnam due to “bone spurs” dancing on the grave of a decorated combat veteran

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Mar 21 • 5:15 PM EDT • Politics • theatlantic.com
Top 5 states with the highest number of safest hospitals, according to new report

Healthgrades named 438 hospitals across 40 states for its 2026 Patient Safety Excellence Award, with Texas and Florida among the top-performing states.

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Mar 21 • 4:25 PM EDT • Health • foxnews.com
March Madness scores: Live updates, schedule for today's NCAA Round 2

Keep up with today's Men's NCAA Tournament second round with scores, highlights, game times and how to watch March Madness Round 2.

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Mar 21 • 4:15 PM EDT • Sports • usatoday.com
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2026 NCAA Men's Basketball Tournament Highlights: Men's Round of 32, More

March Madness continues Saturday, and we've got you covered with all the must-see moments from start to finish!

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Mar 21 • 12:11 PM EDT • Sports • foxsports.com
Ranking 5 most likely March Madness upsets in NCAA Tournament second round

The second round of 2026 NCAA Tournament is underway. Here's a look at the five most likely March Madness upset predictions in the Round of 32.

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Mar 21 • 11:20 AM EDT • Sports • usatoday.com
Hubert Davis' future at North Carolina in serious doubt as pressure mounts after historic collapse

Sources tell CBS Sports that Hubert Davis' future at North Carolina is in serious doubt after a historic NCAA Tournament collapse, with boosters losing faith and questioning their willingness to fund the program.

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Mar 21 • 10:42 AM EDT • Sports • cbssports.com
March Madness live: Who will advance to Sweet 16? Today's schedule, TV listings

Keep up the men's NCAA Tournament on March 21, including game times, TV channels and live updates.

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Mar 21 • 10:42 AM EDT • Sports • usatoday.com
NCAA tournament live bracket updates, scores: Follow men's March Madness Saturday games with Michigan, Duke back in action
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Mar 21 • 10:17 AM EDT • Sports • sports.yahoo.com
What to know about Jaloni Cambridge, Ohio State's star in March Madness

Ohio State's Jaloni Cambridge makes her presence known in the paint and with pull-up jumpers. Here's what to know about her in the NCAA Tournament.

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Mar 21 • 9:27 AM EDT • Sports • usatoday.com
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Duke vs. TCU odds, March Madness predictions: 2026 NCAA Tournament picks from proven model

SportsLine's model has revealed its Duke vs. TCU picks for the NCAA Tournament 2026 second-round game on Saturday

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Mar 21 • 8:32 AM EDT • Sports • cbssports.com
March Madness games today: Ranking the 16-game Women's NCAA Tournament schedule for Saturday

Syracuse vs. Iowa State and Princeton vs. Oklahoma State leads the best Women's NCAA Tournament games to watch on Saturday.

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Mar 21 • 8:24 AM EDT • Sports • usatoday.com
Nebraska, hungry for school's first Sweet 16, ready for Vanderbilt

After winning the school's first-ever NCAA Tournament game on Thursday, Nebraska wants more.

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Mar 21 • 8:20 AM EDT • Sports • cbssports.com
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Trips to the Sweet 16 are on the line in the NCAA tournament on Saturday. Here are 4 things you need to know

The chaos of the opening round of the men’s NCAA tournament is behind us and spots in the Sweet 16 are on the line on Saturday.

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Mar 21 • 6:00 AM EDT • Sports • cnn.com
Where to watch UConn vs. UTSA in March Madness First Round: Time, TV Channel

The No. 1 UConn Huskies face the 16 UTSA Roadrunners in the First Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 21 • 5:07 AM EDT • Sports • usatoday.com
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West Virginia vs Miami (OH) predictions, picks, odds for NCAA Tournament First Round

Our March Madness experts pick the winner for No. 4 West Virginia vs No. 13 Miami (OH) in the 2026 women's NCAA Tournament on

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Mar 21 • 5:06 AM EDT • Sports • usatoday.com
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Your 2026 NCAA Basketball Tournament Viewing Guide: March 21, 2026

Bummed about only one men’s tournament game at a time for 6 hours today? THAT’S WHAT THE WOMEN’S TOURNAMENT IS FOR!

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Mar 21 • 4:11 AM EDT • Sports • sports.yahoo.com
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Nebraska lands the commitment of 3-star athlete Kaden Howard

The feel-good momentum surrounding the Nebraska athletic department continues to build following the men’s basketball team’s first-round NCAA Tournament victory—and it’s now carrying over onto the recruiting trail. The Cornhuskers have secured a commitment from 3-star athlete Kaden Howard, a 5-foot-10, 160-pound playmaker out of Miami, Florida. Howard picked Nebraska over Louisville, West Virginia and […]

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Mar 21 • 2:48 AM EDT • Sports • sports.yahoo.com
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NCAA tournament takeaways, Day 2: Kentucky survives on buzzer-beater, Miami (Ohio) exits and Iowa State loses Joshua Jefferson
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Mar 21 • 1:01 AM EDT • Sports • sports.yahoo.com
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2026 March Madness predictions: NCAA bracket expert picks odds for second round games on Saturday

Best bets for Saturday's second-round action in the 2026 NCAA Tournament

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Mar 20 • 9:17 PM EDT • Sports • cbssports.com
Amazon developing new AI-driven smartphone years after Fire Phone flop: report

Amazon is reportedly developing an AI smartphone codenamed "Transformer" with Alexa integration over a decade after its failed Fire Phone launch.

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Mar 20 • 8:48 PM EDT • Technology • foxbusiness.com
Amazon developing new AI-driven smartphone years after Fire Phone flop: report

Amazon is reportedly developing an AI smartphone codenamed "Transformer" with Alexa integration over a decade after its failed Fire Phone launch.

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Mar 20 • 8:48 PM EDT • Business • foxbusiness.com
Downtown Chico business owner voices concerns over street closures for events

A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO { "@context": "https://schema.org", "@type": "VideoObject", "name": "Downtown Road Closure Dilemma", "description": "A DOWNTOWN CHICO MERCHANT IS EXPRESSING CONCERN OVER THE IMPACT OF STREET CLOSURES FOR EVENTS -- ON THEIR BUSINESS. ACTION NEWS NOW REPORTER BELLA BARBOSA REPORTS FROM DOWNTOWN CHICO", "thumbnailUrl": "https://bloximages.newyork1.vip.townnews.com/actionnewsnow.com/content/tncms/assets/v3/editorial/c/47/c47e26d6-03c3-5f35-bf49-37925ab603d7/69bdedc4eb57d.image.jpg", "uploadDate": "2026-03-20T17:45:00-07:00", "contentUrl": "https://cdn.field59.com/KHSL/1774053903-6e1ef36dd09fbebf020833aee86b60da3b3cca3f_fl9-720p.mp4" } CHICO, Calif. - A downtown Chico business owner is voicing concerns about the impact of street closures for events on local shops. Leann Powell, owner of The Peddler’s Closet, expressed concern about events closing down streets downtown and bringing in food trucks and other shops’ products that directly compete with the brick-and-mortar stores in downtown Chico.Powell said an upcoming event held on a Saturday has brought up concerns for her and other business owners downtown, due to it being a busy day for businesses. "We're already struggling, and then to bring in more businesses on top of our businesses and shut our streets down is absolutely devastating," said Powell.Powell noted a decline in business during events like the Thursday Night Market, where street closures allow outside vendors to set up shop. She shared that while organizers for these types of events often offer booths to local businesses, it does not alleviate the burden."I don't really feel like that's a solution because you're bringing in other businesses, you're shutting the streets down. Yes, we can go down and set up a space, but then you've gotta pay somebody to run that space, plus run your own business for the day, and it's really not, it's really not helpful for us," said Powell.Applying for a street closure permit in Chico involves approval from the Public Works Department, the Chief of Police, and the Fire Chief. Permits can be denied only under a handful of circumstances, such as interference with first responders, previously scheduled construction, or existing permits for the same space.Mayor Kasey Reynolds addressed the issue, saying the city council has tasked staff with reviewing the municipal code for street closure permits with the goal of finding ways to minimize negative impacts on local businesses during events.Reynolds mentioned that any recommended changes might require further direction from the city council, depending on the extent of any changes recommended. googletag.cmd.push(function() { googletag.display('ad-1514992'); });

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Mar 20 • 8:45 PM EDT • Business • actionnewsnow.com
Former Texas women's basketball walk-on scores first NCAA Tournament points

Sarah Graves, a former Texas Longhorns walk-on who became a fan favorite, scored the final basket of the team's first-round March Madness win.

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Mar 20 • 8:44 PM EDT • Sports • usatoday.com
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Michigan vs Saint Louis prediction, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 1 Michigan vs No. 9 Saint Louis in the 2026 NCAA Tournament on March 21

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Mar 20 • 8:21 PM EDT • Sports • usatoday.com
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Tectonic shift: Earth was already moving 3.5 billion years ago

Scientists have uncovered the oldest direct evidence yet that Earth’s tectonic plates were on the move 3.5 billion years ago. By analyzing magnetic fingerprints in ancient rocks, they reconstructed how parts of the planet slowly drifted and even rotated over time. This challenges long-standing ideas that early Earth may have had a rigid, unmoving surface. Instead, it suggests the planet was already dynamic—and possibly setting the stage for life—much earlier than expected.

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Mar 20 • 8:00 PM EDT • Science • sciencedaily.com
WXYZ-TV sports anchor Brad Galli to leave the station

Galli posted on Facebook that he is excited about a new opportunity that he didn't name. He said it will allow him to be home more with his family.

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Mar 20 • 7:35 PM EDT • Sports • freep.com
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Gonzaga vs Texas prediction, picks, odds for NCAA Tournament Second Round

Our March Madness experts pick the winner for No. 3 Gonzaga vs No. 11 Texas in the 2026 NCAA Tournament on March 21

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Mar 20 • 6:41 PM EDT • Sports • usatoday.com
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March Madness bracket predictions, picks for all Second Round games today

Our March Madness experts picked the winner for all games in the 2026 NCAA Tournament on March 21. See them all.

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Mar 20 • 6:17 PM EDT • Sports • usatoday.com
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Pacers' Eddie White named to Hall-of-Fame in hometown

Pacers public relations director and post-game radio host Eddie White was named to the Luzerne County Chapter of the Pennsylvania Sports Hall of Fame.

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Mar 20 • 6:05 PM EDT • Sports • indystar.com
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Hubert Davis buyout: What it would cost UNC to move on from coach after first-round NCAA Tournament exit

The Tar Heels' second straight first-round NCAA Tournament exit adds to growing questions about the program's direction

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Mar 20 • 5:03 PM EDT • Sports • cbssports.com
Reusse: Spotlight on Gophers women’s sports is a welcome sight

The women’s basketball and hockey teams are in the headlines with NCAA tournament games in town and a coaching vacancy to fill.

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Mar 20 • 4:06 PM EDT • Sports • startribune.com
'Keep it Kountry': How Kountry Wayne refused to code-switch and became comedy's most authentic voice

The Georgia-born comedian stands out through his authentic Southern voice and unconventional family dynamic as a father of 10, now breaking into film.

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Mar 20 • 3:53 PM EDT • Entertainment • latimes.com
Texas vs Missouri State predictions, picks, odds for NCAA Tournament First Round

Our March Madness experts pick the winner for No. 1 Texas vs No. 16 Missouri State in the 2026 women's NCAA Tournament on March 20

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Mar 20 • 3:50 PM EDT • Sports • usatoday.com
Texas Tech vs Villanova predictions, picks, odds for NCAA Tournament First Round

Our March Madness experts pick the winner for No. 7 Texas Tech vs No. 10 Villanova in the 2026 women's NCAA Tournament on March 20

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Mar 20 • 3:21 PM EDT • Sports • usatoday.com
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Women's March Madness bracket predictions, picks for all First Round games today

Our March Madness experts picked the winner for all games in the 2026 women's NCAA Tournament on March 20. See them all.

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Mar 20 • 2:27 PM EDT • Sports • usatoday.com
How UConn basketball's defense returned Huskies to national contender status

UConn men's basketball is chasing its third NCAA Tournament title in four years under Dan Hurley. This time, it will start with the Huskies' defense.

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Mar 20 • 12:34 PM EDT • Sports • usatoday.com
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2026 NCAA Men's Basketball Tournament Highlights: Round of 64

The 2026 NCAA Men’s Basketball Tournament continues on Friday, and we’re tracking every top moment of the Big Dance!

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Mar 20 • 12:14 PM EDT • Sports • foxsports.com
2026 Women's NCAA Tournament live: All the highlights, scores, buzzer-beaters

Keep up the women's NCAA Tournament on March 20, including game times, TV channels and live updates.

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Mar 20 • 10:56 AM EDT • Sports • usatoday.com
From The Sports Desk: How’s your backet holding up?

The women's tournament kicks off, more upsets expected and a Premier League preview.

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Mar 20 • 10:02 AM EDT • Sports • nbcnews.com
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Who is Nate Burleson? Why has he replaced Ernie Johnson for NCAA Tournament?

Where is Ernie Johnson? Who is Nate Burleson? Here's what you need to know about CBS and TNT Sports' studio hosts for NCAA Tournament.

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Mar 20 • 8:29 AM EDT • Sports • usatoday.com
LSU's Flau’jae Johnson is back on March Madness stage. What to know about star guard

Star guard Flau'jae Johnson leads second-seeded LSU into a first-round NCAA Tournament game against the Jacksonville Dolphins. Here's what to know.

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Mar 20 • 8:03 AM EDT • Sports • usatoday.com
Saint Mary’s renames science building to Mathile Science Hall

Saint Mary’s held a renaming ceremony for the College’s Science Hall, which will now be known as Mathile Science Hall.

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Mar 20 • 8:00 AM EDT • Science • ndsmcobserver.com
Valve releases SteamOS 3.8 preview with Steam Machine support and wider handheld compatibility

Valve SteamOS 3.8 preview is here Valve has released SteamOS 3.8.0 Preview, codenamed "Second Clutch," for the Steam Deck Preview channel. The update adds

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Mar 20 • 8:00 AM EDT • Technology • videocardz.com
Where to watch Michigan State vs. Colorado State in March Madness First Round: Time, TV Channel

The No. 5 Michigan State Spartans face the 12 Colorado State Rams in the First Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 20 • 5:09 AM EDT • Sports • usatoday.com
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Where to watch North Carolina vs. Western Illinois in March Madness First Round: Time, TV Channel

The No. 4 North Carolina Tar Heels face the 13 Western Illinois Leathernecks in the First Round of the women's NCAA Tournament. Here's how to see all the action.

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Mar 20 • 5:08 AM EDT • Sports • usatoday.com
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Fowler College of Business names founding director of ‘real-world’ lea

Professor Iana Castro will head the Shaw Family Center for Experiential Learning

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Mar 20 • 3:39 AM EDT • Business • sdsu.edu
March Madness second-round schedule: How to watch, follow Saturday's NCAA tournament action
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Mar 20 • 1:18 AM EDT • Sports • sports.yahoo.com
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12 hours, 4 games, 1 unavoidable truth: There is nothing better than the first day of March Madness

The thing that always gets me on the first day of the NCAA Tournament are the school buses, the ones chugging along stuffed with kids. Because it is, of course, Thursday morning and this is what ordinary people do on a Thursday morning.

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Mar 20 • 12:46 AM EDT • Sports • cnn.com
Men’s NCAA Tournament Second Round Opening Odds: TCU vs. Duke

Horned Frogs battle top overall seed Blue Devils for a spot in the Sweet 16

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Mar 19 • 11:59 PM EDT • Sports • sports.yahoo.com
March Madness live updates, scores, bracket: Women’s NCAA tournament First Four wraps up with Virginia and Southern advancing
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Mar 19 • 11:33 PM EDT • Sports • sports.yahoo.com
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March Madness leads to big business for Philadelphia hotels

This is the 29th time the city has hosted the NCAA tournament, and it's the first time March Madness games have been played here since 2022.

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Mar 19 • 11:33 PM EDT • Business • 6abc.com