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‘Democrats Are Behind’: PAC Wants Party to Catch Up on A.I.
The group is starting with more than $10 million and says it intends to support midterm House candidates in swing states.
AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD
With a detailed data drop that AstraZeneca’s R&D chief described as an internal “science success story,” the British Big Pharma has secured an FDA priority review for what it believes could become a flagship biologic in chronic obstructive pulmonary disease (COPD). In detailed results from the late-stage Oberon and Titania trials—first teased in March and detailed in full at the European Respiratory Society Congress in Barcelona this week—the drugmaker laid out the extent of its IL-33 inhibitor’s potential to reduce moderate and severe exacerbations in a wide range of COPD patients still struggling with those “lung attacks,” as AstraZeneca’s Sharon Barr, Ph.D., called them, despite using standard-care inhaled therapy. In the headline results, a 300 mg dose of tozorakimab given once every four weeks curbed those moderate and severe exacerbations in the studies’ primary population of former smokers by 29% in the Oberon study and 34% in Titania. In the overall population of both current and former smokers, these reductions were 30% and 29%, respectively, versus placebo and inhaled standard of care. The benefits also extended to clinically meaningful exacerbation reductions in all prespecified patient subgroups and specifically turned up promising signals in patients across a range of blood eosinophil counts, with Barr telling Fierce that “it’s the details that make this even more exciting than the high-level results that we’ve already shared.” In fact, during AZ’s tozorakimab poster presentation at the ERS 2026 Congress this past weekend, attendees were so enamored by the data that event organizers had to encourage people to clear the room and look at the other presentations on offer, Barr said in an interview. “I think it really speaks to the fact that there is a lot of buzz around these data because the entire respiratory community has been so desperate for new therapies for these patients,” she explained. The respiratory disease continues to represent a “staggering unmet medical need,” Barr said, highlighting the COPD exacerbations that the Oberon and Titania studies homed in on, which she added carry a greater mortality risk than a heart attack. “When a patient has a severe exacerbation, only about half of them are still alive within three and a half years,” she pointed out. As for tozorakimab specifically, Barr christened the molecule “an AstraZeneca science success story,” harkening several years back to the point at which researchers began to explore IL-33 as a driver of respiratory disease, and COPD in particular. At the same time, “there was still so much that wasn’t understood,” she admitted, highlighting the insight that IL-33 signals through both ST2 and EGFR through the RAGE pathway, a discovery Barr attributed to AstraZeneca's own scientists. Understanding the need to tackle both pathways in COPD—and aware of competitor candidates in the hopper, including one that bound ST2—the company ultimately had to make some “courageous decisions,” Barr said. These included taking a prior COPD molecule offline and going back to the drawing board to reinvent its potential IL-33 label “to make sure that we had a molecule that could block signaling through both arms of the pathway, through both the reduced form and the oxidized form, knowing that we wouldn’t be first, but striving to be best.” “When we put [tozorakimab] into the clinic, we firmly believed that we had a differentiated molecule, and we saw the other molecules blocking just ST2 or partially blocking IL-33, unable to deliver two positive pivotal studies in COPD,” Barr explained. “We kept marching forward because we believed our molecule was differentiated, and now I think we have the clinical validation that supports that.” Ultimately, AstraZeneca finds itself on much better footing these days when it comes to potential biologic rivals to tozorakimab in COPD. Sanofi and Regeneron’s Dupixent, for instance, is approved to treat COPD exacerbations in patients with high eosinophil counts, but not low ones. Meanwhile, the future has become cloudier for other next-gen IL-33 candidates from Sanofi and Regeneron, as well as Roche, which have suffered trial flops in recent years. One other potential ingredient for AstraZeneca’s success in its duo of studies was that the company was “ambitious in the trial design, willing to look at an all-comers population,” Barr said, “and willing to enroll the most severe patients.” Prior studies for would-be biologics rivals in COPD “avoided enrolling” those patients, she pointed out. She also highlighted the Big Pharma’s painstaking design of exacerbations in its trial, which “gave us a very rigorous readout,” and pointed to “the extra effort and investment” the company put in to understand the effect of mucus plugs in patients. Barr described mucus production as a “key feature in disease diversity,” noting that mucus plugs—obstructing clumps of mucus that block patients’ airways—are associated with worse outcomes in COPD. In its data announcement, AstraZeneca noted that an integrated analysis of Oberon and Titania found tozorakimab “demonstrated a reduction in patients’ mucus plug score,” with the pharma claiming its biologic is the first to deliver such results in a broad COPD population. “So being able to reduce those mucus plugs, we expect, is an important part of driving benefit for patients who are living with COPD,” Barr said. Again touching on the breadth of the study populations, Barr added that tozorakimab “worked across all eosinophil levels in both current and former smokers across all levels of lung function,” which she suggested “really simplifies decision-making for clinicians, and it allows them to offer therapy to the broadest possible patient population.” In the highest patient eosinophil count group, tozorakimab helped chart a 43% reduction in exacerbation risk, which Barr stressed were “unprecedented data.” In the mid-level group, AZ’s drug delivered a 23% reduction and, in the lowest group, a 34% reduction in eosinophils, which Barr said suggests efficacy “in all patient subgroups.” As for AZ’s recent guidance upgrade on the medicine’s sales opportunity, the lift from a $3 billion to $5 billion range to $5 billion plus was informed by multiple factors, Barr said, including the fact that “in 2024, there were multiple competitors, and there aren’t anymore.” Additionally, “we know that this is a massive unmet medical need, and this is a really incredible set of data that we think will be very convincing to the clinical community,” Barr said. Looking ahead to a potential evolution of the COPD treatment landscape, Barr noted that most patients start treatment in the community with an option like a triple therapy, and for them, having an option like AstraZeneca’s inhaler Breztri will remain a “really important part” of that journey. But of the patients uncontrolled on triple therapy, which Barr described as “about half of them today,” just a “small fraction” are currently eligible for biologic therapy, which she emphasized AstraZeneca is working to change. Understanding that COPD is not a “one-size-fits-all” disease, AstraZeneca is also looking at its antibody drug Tezspire for patients with T2-driven disease, and the company continues to think about new mechanisms for tackling COPD through both systemic and inhaled drugs, Barr said.
Mackenzie, Bresnahan, McCormick To Speak at "Trumpapalooza" in Dallas
Pennsylvania will be well represented at the podium as the Republican Party holds a midterm national convention in Dallas on Wednesday and Thursday. A pair of GOP congressmen - Reps. Ryan Mackenzie (R-07) and Rob Bresnahan (R-08) - and Sen. Dave McCormick will be among the 109 officials, candidates and…
New Hampshire voters pick midterm nominees as Sen. Shaheen's exit sparks scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the 424-seat state Legislature on Tuesday, and incumbents aren’t the only familiar names on the ballot.
Florida IAM Members Focus on Political Mobilization at Fall Conference
The IAM's Florida State Council recently held its fall conference, bringing together union leaders and delegates to focus on political education, voter mobilization, and strengthening the voice of working families across the state. Led by President Mike Phillips, the conference emphasized the importance of supporting pro-labor candidates and increasing member participation in the political process.
How 2026 candidates are targeting health care "corruption"
They're accusing opponents of being in the pockets of drugmakers or health insurers.
What to Watch in Tuesday’s New Hampshire Primary Elections
Voters will nominate candidates for one of the most high-stakes Senate races in the country. And a Democratic House primary has emerged as a test of the party’s establishment.
Former Knox County Trustee Justin Biggs' friends left office with him
Justin Biggs hired friends and inflated his office's budget to give them raises. A bunch of them quit before his successor took over.
Candidates offering healthcare slogans, not solutions: Dr. Ashish Jha
“There’s a set of things we can do to lower health care spending, but the slogans are not going to get there,” Jha said.
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | K-DAWN
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | Talk Radio 1210 WPHT
New Hampshire voters pick nominees as Sen. Shaheen’s exit sparks a scramble for key seats
New Hampshire primary voters are choosing candidates for Congress, governor and the state Legislature, with the retirement of U.S. Sen. Jeanne Shaheen creating the most competitive races | WWL
Politics on parade: Candidates join Buena Vista Labor Day celebration
With the midterm elections fast approaching, the annual Labor Day Parade brought candidates for the U.S. Senate and the House of Representatives to Buena Vista on Monday.
Man arrested after alleged attack on Amy Acton; candidates across Ohio denounce political violence
Patrick Havas, 38, faces charges after Canfield Fair incident as candidates across Ohio denounce political violence
Political candidates across country attend Labor Day events
PORTLAND, Maine — Troy Jackson was a longtime labor activist and logger before he unexpectedly became the Democratic nominee for U.S. Senate in Maine. On Monday, he returned to a
Midterm elections head into the home stretch as candidates attend Labor Day events
This year’s campaigns already have been combative, busy and expensive.
Pfaff tells ‘UpFront’ Dems must focus on ‘bread and butter’ issues to win in November
State Sen. Brad Pfaff says Democrats must focus on "bread and butter affordability issues" in order to unite and win in November as he hosted numerous candidates at his annual corn roast at the La Crosse County Fairgrounds.
Kathy Hochul is trying to hold the center in a disruptive political age
The moderate New York governor is running for reelection and must help her down-ballot candidates win.
Midterm elections head into the home stretch as candidates hit Labor Day events
Candidates in key November races are spending Labor Day weekend stumping at festivals, union halls and parades
Midterm elections head into the home stretch as candidates hit Labor Day events
Candidates in key November races are spending Labor Day weekend stumping at festivals, union halls and parades
Midterm elections head into the home stretch as candidates hit Labor Day events
Candidates in key November races are spending Labor Day weekend stumping at festivals, union halls and parades
Midterm elections head into the home stretch as candidates hit Labor Day events
Candidates in several states with competitive House and Senate races are beginning the stretch run of election season with Labor Day events at festivals, union halls and parades.
Factbox-The Nine Midterm Races That Will Decide Control of the US Senate
By Andy Sullivan WASHINGTON, Sept 7 (Reuters) - Democrats need to pick up four seats from Republicans to win control of the 100-seat Senate in the midterm elections on November 3. While voters will pick candidates in 35 states, independent analysts only see nine of those races as competitive.
Fact-Checking Midterm Ads Referring to Jeffrey Epstein
Candidates have traded attacks on votes to releasing the Epstein files and political donations from those with links to Jeffrey Epstein.
Football players highlight latest Public Opinion-Aberdeen News AOTW poll
Ten more Watertown and Aberdeen area high school athletes are candidates for our latest AOTW poll.
Far-left Democrats had a huge summer. Now they have big demands for party leaders
The left wing of the Democratic Party flourished this summer as fed-up liberals in key races across the country have eschewed traditional, more moderate candidates in favor of hard-charging progressives.
Gubernatorial Candidates Rhoden, Ahlers Spar Over Agriculture, Education, Health Care
Ahlers, a former lawmaker from Dell Rapids, criticized the state’s strategy on economic development for agriculture, arguing that too much of the money doled
3 N.C. politicians to speak at GOP midterm convention in Dallas
U.S. Rep. Richard Hudson and candidates in key U.S. House and Senate races are set to address this coming week’s gathering.
3 N.C. politicians to speak at GOP midterm convention in Dallas
U.S. Rep. Richard Hudson and candidates in key U.S. House and Senate races are set to address this coming week’s gathering.
Who Are More Candidates For Miami Heat's Final Roster Spot?
After landing Giannis Antetokounmpo this offseason, the Miami Heat have put together a strong bench unit. With their final roster spot, which veterans should the team target?
A whiplash election year enters its final stretch as Donald Trump holds wild cards
Both parties are stepping up efforts for their candidates in contentious swing states as many consider the vote a referendum on Trump.
This Campaign Finance Whiz Helps Hawaiʻi Politicians Keep Their Books In Order
After 33 years with the state Campaign Spending Commission, Tony Baldomero is now working for candidates so they file “true and accurate” expense reports.
Politics at the MN Fair: Candidates mingle with voters ahead of November
Gone are the days of high-profile debates for top offices at the Great Minnesota Get Together. The last Fair debate for a top statewide office — whether it be for governor or U.S. Senate — was in 2018.
An ‘albatross’ or a GOP turnout force: Trump’s role in Texas midterm elections
With a president down in the polls coming to Dallas for a convention, navigating the politics can be tricky for some midterm candidates.
New Hampshire Sept. 8 primary: Full list of candidates on the Seacoast
New Hampshire's primary election will include contested battles for U.S. Senate and House, governor, executive council and state lawmakers.
Affordability takes center stage as Shapiro and Garrity craft their economic pitch for Pennsylvania voters
Exhausted by high gas prices and stagnant wages, voters most want the candidates to address cost-of-living concerns, according to a recent poll.
Outside money fuels bitter attacks in NH’s CD1 Democratic race
As NH's 1st District Democratic primary nears, candidates use "red boxes" to guide outside PACs as spending tops a record $12 million.
Outside money fuels bitter attacks in NH’s CD1 Democratic race
As NH's 1st District Democratic primary nears, candidates use "red boxes" to guide outside PACs as spending tops a record $12 million.
Liverpool sporting director Richard Hughes leaves position, expected to join Al Hilal
Hughes, 47, worked for two-and-a-half years at Anfield and the club are expected to look at internal candidates to replace him.
Musk has started spending money to help Ken Paxton. Will it help change the course of the Texas Senate race?
For months, Texas Republicans have anxiously awaited the arrival of national resources to help boost Ken Paxton, one of the GOP’s most vulnerable Senate candidates.
The mystery behind an audio clip that helped upend a Senate race
Artificial-intelligence tools increasingly allow political actors to fool voters — and help candidates cast doubt on reality.
Flock cameras draw opposition from across the political spectrum
As political races heat up heading into the midterms, candidates from both parties are increasingly joining the fray to voice concerns over Flock surveillance cameras.
AI-generated ads have come to Oakland politics. Accessible solution
Slowly but surely, more campaigns are using videos and songs made with artificial intelligence. We asked local candidates and experts about the implications.
In boost to GOP, Supreme Court says parties should get lower TV ad rates
The Supreme Court ruled Friday that political parties should get discounted TV ad rates when they coordinate spending with candidates.
Gubernatorial candidates present drastically different plans to improve healthcare costs, access
Maine’s three gubernatorial candidates agree on health care struggles but propose vastly different solutions for improving access and costs.
Supreme Court Sides With Republicans in TV Ad Fight
Republican groups had asked the court to clear the way for political parties to pay the same low-cost ad rates as candidates, a move that could undercut a Democratic advantage in the midterms.
New Supreme Court ruling helps GOP buy cheaper TV ads for critical midterms
The Supreme Court allowed political parties to access discounted advertising rates, potentially aiding GOP candidates in the midterm elections.
Supreme Court backs Republicans in election ad rate dispute
Republicans asked the court to allow party committees to receive the same ad discounts that candidates themselves benefit from.
Second-year breakout candidates for 2026 fantasy football
Chet Gresham takes a look at 5 players set for a second-year breakout for 2026 fantasy football
Elon Musk’s super PAC starts spending to help GOP in midterms, including Texas’ Ken Paxton
Elon Musk's America PAC has disclosed its first spending on Republican candidates — roughly $800,000 across Senate and House races in multiple states. Who do you think this spending will impact most?
2026 NH Democratic CD1 Debate: Health care plan
Carleigh Beriont, Sarah Chadzynski, Stefany Shaheen, Maura Sullivan and Christian Urrutia, the Democratic candidates to represent New Hampshire's 1st District in Congress, share the plan they would implement to tackle high health care costs, and whether that would mean higher taxes for the middle class.
Top employees for data center company eyeing Yellowstone County made matching political donations before announcing plans
The Quantica employees gave the same amount to the same candidates and on the same days in 2024.
Trump says he’ll campaign for Republicans in 35 races ahead of the midterms
The president said he’ll travel to help out GOP candidates in competitive contests, including the Senate races in Alaska and Texas.
2026 NH Republican CD1 Debate: Health care costs
Brian Cole, Anthony DiLorenzo and Hollie Noveletsky, the Republican candidates to represent New Hampshire's 1st District in Congress, discuss what they can do legislatively to make health care more affordable for Granite Staters.
GOP ads contradict Trump’s rosy view of the economy
For months, President Donald Trump has falsely claimed that consumer prices are falling ahead of this year’s 2026 midterm elections. Now some Republican candidates are running campaign ads that acknowledge reality. CNN’s Daniel Dale reports.
Progressive Senate candidates rack up primary wins even as they get outspent
Plus, a pro-Trump group hits the airwaves.
Most Lancaster County Republican candidates decline nonpartisan forum invitations
The League of Women Voters of Lancaster County has canceled all but one of its five scheduled candidate forums due to a lack of Republican participation.
South Carolina governor candidates, Johnson and Wilson, to debate
Alan Wilson and Jermaine Johnson will face off in a televised debate ahead of the South Carolina gubernatorial race.
DeSantis endorses Florida GOP slate including Byron Donalds in governor's race
Florida Gov. Ron DeSantis endorsed a "slate" of candidates that included GOP gubernatorial candidate Rep. Byron Donalds.
August Monthly Review: ChatGPT In Epic
Death, taxes, another frontier lab healthcare launch inspiring truly insane LinkedIn takes. As much as I want to stay away, I repeatedly am the crewman unplugging his ears whenever we pass these sirens. So it’s not the first and probably not the last time we dial up the typewriter rather than tie ourselves to the mast. The full blow-by-blow timeline: Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe The End of the Standalone PHR (Jan 8): ChatGPT Health arrives for consumers, at the time powered by b.well. I was bullish on the approach in that the best way for the PHR to finally solve distribution was to meet consumers were they already are (i.e. When Horizontal Meets Healthcare (Jan 9): OpenAI for Healthcare puts out the shingle for enterprises, with SharePoint ingestion standing in for the EHR integration the product actually needed. Another One: Anthropic’s Healthcare Debut (Jan 16): Claude's version, on HealthEx rails instead of b.well, with Agent Skills for FHIR development as the one true vertical-specific investment. ChatGPT for Clinicians: The Trap Sprung (Apr 24): OpenAI filled in the missing GTM middle with a free product for verified clinicians, effectively peeling the enterprise wrapper off ChatGPT for Healthcare and taking the PLG fight directly to OpenEvidence. OpenAI’s Second Attempt at Health (Jul 31): a relaunch of their patient specific app, now branded Health in ChatGPT, where the privacy partition came out, the connectors thinned, and b.well disappeared in favor of first-party FHIR work against a smaller network Beyond a Shingle So what was announced now? Today, we’re introducing a new electronic health record integration that brings authorized patient context from Epic into ChatGPT for Healthcare, along with the Healthcare Public Data plugin for direct, structured access to official healthcare datasets like PubMed, DailyMed, and CMS Coverage. Together, these capabilities bring ChatGPT closer to the systems and sources healthcare teams trust, while supporting the controls and compliance healthcare work requires. The core portfolio is unchanged from prior announcements we delineated and discussed (aside from the relaunch of patient-facing). Since trade publications still seem to be confusing them by using the wrong names: Enterprise sales motion: ChatGPT for Healthcare Protecting their core product / PLG: ChatGPT for Clinicians Consumer/patient-facing product: Health in ChatGPT So really, this is a feature release (specifically for ChatGPT for Healthcare when it comes to EHR integration). What’s cool about it, though, is that we are moving beyond just putting out a shingle. Everything in the January enterprise launch was horizontalizable: Horizontal tech companies thus generally start verticalization with their “putting out a shingle phase”. Telling the world you’re open for business as a horizontal tech company reliably attracts early inbound interest from buyers who are already trying to force-fit horizontal tools into domain-specific workflows and are eager for any signal that the vendor intends to support their use case more directly. Nothing was really vertical specific, which is exactly what you'd expect from the ultimate hypergrowth horizontal company dipping their toes into specific industries. But eventually you have to stop changing the sign on the door and start changing the product. Can you guess where the horizontal product was going to run out of road? This is the core dilemma writ large: verticalization requires differentiation, while scale economics of consumer and horizontal push toward unification. I’ve buried the lede so deep here it will be painful to some readers, but what should be shocking to no one is that my perspective is that EHR integration is the only path that meaningfully resolves this tension for ChatGPT for Healthcare. Integration with Microsoft Sharepoint is fine, but it is categorically insufficient for any product that hopes to influence clinical decision-making. SMART Money Well here we are, eight months later! Real vertical investment has begun, which surprised a few people. One friend in the industry messaged me: “Absolutely no way Epic gave ChatGPT API access.” Looking forensically at the announcements, the integration is notably read-only across appointment notes, laboratory results, medications, and specialist documentation. So while I’m not a betting man, I'd wager the house this is a SMART on FHIR launch: That sounds a lot like USCDI! The recommended path for the workflow they outline would be SMART on FHIR Their Health AI lead’s post is evocative of both standalone and EHR launch SMART, which another termed “ChartGPT” and “EHR Plugin” The implementation burden for SMART on FHIR is the lowest of the available integrative paths This is the team who literally did patient-facing SMART on FHIR with Epic last month Most importantly, if you’re a horizontal company, you generally still haven’t taken the full plunge and thus (overly) value reusability. SMART on FHIR is the logical compromise: healthcare-specific enough to matter, but standardized enough to reuse. Nobody Asked Judy Another friend asked “I thought they had to go to each health system, or did they go direct to Epic and now health systems opt in?” Given the trust paradigms in healthcare, this functionally cannot be Epic hoovering up all the data for OpenAI and shoving ChatGPT in their customers’ faces (or they would revolt). However, I do believe the aforementioned terrible coverage by TechCrunch and other outlets is probably responsible for that question, given the 325 million reference. When using FHIR as a business associate to an Epic customer, there is no EHR gatekeeping to speak of, as that isn’t how fhir.epic.com works: You register an app You pick your APIs You test against the sandbox APIs You list as “Ready for Production” Hospitals pick your app You test and go live with them Bluntly, nobody had to say yes or no in Verona (nor were they given the chance). Vendor Services (their next developer tier up that I doubt OpenAI is using quite yet in this initial release) certainly has contractual paperwork that some resent, but even there, the twin pressures of mounting antitrust and information blocking make outright gatekeeping increasingly fraught. My friend’s sentiment is, to me, representative of a broader industry neurosis, perhaps a sort of scar tissue of prior eras: people assume the gate is still there and never actually try the door. There are certainly other ways Epic (and any EHR) can put its thumb on the scale, but they are not so dumb as to stand in front of a federally mandated API and play bouncer at this exact moment in time. So I think they can and probably should go deeper, as this release is at best parity and at worst behind vertical-specific competition. OpenEvidence did a basic SMART launch with Sutter Health in February, allowing for more convenient evidence search by providers. They then add patient-context (the equivalent SMART on FHIR flow to what we see here) when Cedars-Sinai went enterprise-wide in May. UpToDate has four distinct applications across deeper workflows like patient engagement listed in Epic Showroom and announced a partnership with Epic to power Art at UGM Abridge and other ambient scribes have invested deeply into the deepest bidirectional clinical copilot workflow with integrations well beyond SMART on FHIR. In that light, the “Who is OpenAI primarily targeting here?” is clear. This release brings them into striking distance of OpenEvidence, but not the others quite yet. They are the only one of the three you can reach without building something truly Epic-specific. When will they go further? Competition is a great motivator to overcome the horizontal demons and start building things that can’t be reused: not across industries, not across EHRs, maybe not past the customer you built them for. That’s the price of actually verticalizing. The question is if and when OpenAI will be willing to pay it. Month in Review Here is the monthly review. As a reminder, this is a regular round-up of the month’s posts and other content to surface things you may have missed across regulation, litigation, interoperability, and beyond. AI assistance is used in these bullet summaries so I can focus on articles. Articles Published: None this month Video Content: The Information Exchange: Standards-based Thruple Edition (Aug 14): Back to school for us too, with Brad reporting in from the CMS Health Tech Ecosystem’s one year anniversary in DC. We get into the January CMS-0057 deadline, the fall rulemaking reading list, and why enrollment still keeps most apps off FHIR. The Information Exchange: Epic Dúnadan Edition (Aug 25): A UGM roundup with Ryan Brickner joining for the first time to check our takes against what the building actually thinks. Rangers, Ergo sitting on top of EHI, and a down-market lineup that needs some cuts. Regulatory: Stacked Deck, Bad Hand (Aug 05): ONC’s website refresh took the entire HIT Policy Committee record with it, so I rebuilt the archive and went looking for the regulatory capture story everyone assumes is buried in there. Stacking the deck and winning the hand turn out to be very different things. The Sixth Generation of Patient Access (Aug 19): A quick catalog of the five generations of patient access we’ve layered on since HIPAA, and the two candidates now competing to be the sixth. One is planned. The other is the market routing around the plan entirely. Court cases: Three Cases Walk Into a Docket (Aug 06): Two surprise settlements cleared the board in a single week, and then Judge Maddox dropped ninety-four pages on Vyne v. Henry Schein. The sleeper is a DMCA holding that makes direct-to-database a considerably riskier business model. Epic v. Health Gorilla: Into the MDL (Aug 10): Nine class actions are headed to Miami, and the Panel signaled it wants to bring the case that spawned them along too. That would leave Epic arguing the requests were obviously fraudulent in one courtroom and unknowable in the other. Amazon v. Perplexity: Agents Are Legalized! (Aug 11): The Ninth Circuit vacated the injunction against Comet, holding that the user is the one accessing the servers rather than the company that built the agent. A real win for agentic access, and a much narrower one than the headline suggests. Veeva v. Epic: Come At Me, Bro (Aug 26): Epic’s response brief wants the dismissal affirmed and, unusually, wants the opinion published as precedent. Buried in it is Epic’s own description of what its non-competes actually prohibit, which current and former employees should read closely. EHRs: The Contract Epic Would Never Sign Today (Aug 04): A 1999 SEC exhibit catches Epic licensing nearly its entire product line, Tapestry included, to the company that became TriZetto. The marketing services menu attached to it is the part that will make you blink. Forecast from Verona (Aug 07): The Epic Almanac makes one argument six different ways: the AI is only as good as the networks behind it. Emmie headlines, Art’s context stack is the most ambitious part, and Penny finally gets an autonomous coding date on the calendar. Works With Epic MyChart (Aug 17): Epic’s first new Showroom category since the death of Workshop certifies hardware instead of software, badge on the box and all. Made for iPhone, but for blood pressure cuffs, and rough news for anyone selling the RPM stack sitting in between. UGM Hot Takes 2026 (Aug 20): Everyone else covered the AI announcements, so I went after Savvy deleting the payment gateway, Rangers as Boost with the timer removed, and a down-market lineup with too many entries. Plus the Health Grid tidbits I cannot help myself on. MyChart Central Grows Up (Aug 24): Device data and Emmie turn Epic’s identity hub into a full consumer platform, which is both a logical answer to ChatGPT and a bit of a mistake. It also happens to be the best scraping target Epic has ever shipped. Industry Analysis: The Wrong Yardstick (Aug 12): Vertical software keeps getting judged against Superhuman and Notion, which is the wrong bar entirely. Your user is comparing your product to a whiteboard and forty phone calls before lunch. Primitives vs. Abstractions (Aug 27): Developers want building blocks, systems of record prefer to hand out business logic, and both sides have a real case. There’s no test from the outside that separates the engineering reason from the competitive one, which is why this keeps ending up in court. Cross-industry Comparisons: The Two Kinds of Platform Power (Aug 18): Attention power and record power are different problems that keep getting handed the same regulatory toolkit. Congress’s latest swing at Big Tech shows both what’s possible and where it falls apart. The Dogs of (Platform) War (Aug 21): A CourtListener alert turned up a property management fight with healthcare’s exact shape and none of the Cures Act. Shell prospects, ghost accounts, a notetaker bot that came back to haunt someone, and a lawyer arguing both sides of the same theory in two states. Fractals All the Way Down (Aug 31): Yardi dominates property management right up until you zoom into one segment, where AppFolio owns it outright and Yardi doesn’t appear at all. Where you draw the line around a B2B software market is about to decide an awful lot of cases. Other News: If Judy Had the Courage (Aug 13): A short eulogy for the era when software was allowed to look insane: WinAMP, bold colors, and everything the grey chatbot era has taken from us. External Media: Portland Monthly Health Tech Meetup: Erin O’Brien channeled my own feelings - maybe it’s just because it’s August and beautiful, but the monthly edition of the PDX Health community meetup was a ripper. Make sure to reach out if interested to join for the next one. STAT’s Coverage of Epic This Month: Brittany Trang of STAT did a fantastic job of breaking the FTC investigation that’s been lurking, as well as UGM related coverage, so I had to give her her wish of a meme. Fall Conferences: I’m pumped to be kicking off my fall conference season in NYC at Nabla Accelerate next month, which Chrissy provided the link to apply for. Here’s the rest of my schedule in case you want to meet up: Commonwell (Redwood Shores, CA): Oct 13-14 Open@Epic (Madison, WI): Oct 21-22 eHealthExchange (Austin, TX): Oct 27 Sequoia Project (Austin, TX): Oct 28-29 HLTH (Vegas): Nov 15-18 RSNA (Chicago): Nov 29-Dec 3 Posts I Liked: HTI-6 Should Unbundle API Certification: Josh Mandel makes the case that HTI-6 should split (g)(10) into separate authorization and data certifications, so a PACS or a genomics platform can certify only the role it actually performs. Imaging is the urgent example, but the structure solves a much bigger problem. On implementing ePrior Auth with Epic: Scott Rossignol’s field notes from a live ePrior Auth build on Epic, including the two app registrations nobody warns you about and the CPT mapping problem waiting at the end. CMS-0057 implementations are going to be such a beast. Healthcare point solutions are starting to look a lot like streaming services: Spencer Dorn runs the cable-to-streaming arc against health IT and lands squarely on the bundling half of the cycle. Bundling can be good! It can also be bad! Life is nuanced. Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe
Candidates, voters, merch: Politics bingo ingredients are everywhere at Minnesota State Fair
Turn your State Fair visit into a hunt for politics bingo.
Osborn, Ricketts spar on health care, immigration, beef imports at Nebraska State Fair
Candidates questioned on Medicaid, ICE funding and foreign beef imports.
Deadline day: Enzo Fernandez makes £125m Manchester City move
Manchester City have equalled the British transfer record by signing Chelsea midfielder Enzo Fernandez for £125 million ($169 million) at the end of a dramatic deadline day in the Premier League. From title contenders to relegation candidates, teams across the division spent big to bolster their squads before summer window closed at 11 pm (2200 GMT) on Tuesday.
WATCH: Trump says 'Medicare for All' doesn't work
The president was asked about Democratic candidates who want to use Medicare to provide universal access to health care — and he said his approach to have confidential drug pricing deals was superior.
Mountain View City Council candidates square off at business forum
Ahead of the November election, the Mountain View Chamber of Commerce held a forum last week to give voters an early look at the policy positions of eight candidates vying for a seat on the City Council.
Minnesota State Fair: Political Hub, Always Center Stage
It's more than food on a stick, long lines and Grandstand shows. The Minnesota State Fair has always been a proving ground, outreach opportunity, and sometimes divisive stage for politicians, from local candidates up to the nation's highest office. Yes, politics is yet another State Fair tradition. | 830 WCCO
AI is hurting US politics. Here’s how candidates could use it for good
The technology can help candidates listen more deeply to voters, as examples from Japan and Scotland show
The U.S. Supreme Court removed limits on political parties coordinating with candidates. What does that mean for Philly’s elections?
Local elections lawyers said the Supreme Court's decision could potentially boost the spending power of Philly's political parties.
Voters hate data centers. Candidates from both parties are scrambling to respond
Across the country and the political spectrum, candidates are embracing a growing backlash to artificial intelligence and the infrastructure required to power it.
Donald Trump threatens to report ‘Meet the Press’ moderator Kristen Welker to FCC for ‘punishment’
Donald Trump is lashing out at NBC News’ Kristen Welker, long one of the primary objects of his ire, for saying his endorsement of recent candidates for elected office have had ‘mixed results.’
Opinion | Democrats Have an Identity Politics Problem. Just Not the One You Think.
Instead of rallying around their candidates, Democrats are falling out among themselves.
Boston Mayor Wu-aligned Super PAC spent $84K on challengers to senators she opposes
A Super PAC with ties to Wu has spent $84K+ supporting candidates challenging Nick Collins and William Brownsberger, two state senators she’s trying to knock off in Tuesday’s primary election.
Political Campaigns Are Quietly Paying Influencers to Support Candidates
Their videos have proliferated on social media, but the payments are frequently hidden from viewers.
Meet the Black candidates seeking history in governor's races this fall
A historic group of Black candidates are running for governor in 2026, with several seeking to expand Black representation in state leadership and make history this fall.
Politics Unplugged Podcast: Headline roundup with Jim Small
Arizona Mirror editor Jim Small joins us to talk about new poll numbers, and shenanigans with candidates running under the Green Party name. Then Dennis and Colin talk about the weird political attacks on the WNBA.
Politics Unplugged Podcast: Headline roundup with Jim Small
Arizona Mirror editor Jim Small joins us to talk about new poll numbers, and shenanigans with candidates running under the Green Party name. Then Dennis and Colin talk about the weird political attacks on the WNBA.
Commentary: The MBA Applicants Business Schools Are Losing Before They Apply
Global MBA applications are rising – but U.S. programs are increasingly losing candidates before they even apply.
3 waiver claim candidates for the Bengals during final cuts
Cameron Williams is a young prospect at tackle that could become available this weekend.
Rep. Wozniak votes to crack down on corporate influence in Michigan politics
State Rep. Doug Wozniak this week voted to get money out of politics by blocking state-regulated utilities and companies with major government contracts from donating to political campaigns and candidates. The state House approved the Michiganders for Money Out of Politics (MMOP) citizen-initiated proposal after more than half a million Michigan residents signed petitions supporting […]
Jasmine Crockett has no plans to campaign for James Talarico
Jasmine Crockett tells Laura she will not be campaigning with James Talarico in the closely-watched Senate race in Texas. Crockett says she’ll be supporting down ballot candidates in the midterms who are often overshadowed.
Gubernatorial candidates Phil Weiser, Greg Lopez spar, as Marx skips debate
Two of the candidates for Colorado governor squared off in a televised debate on Thursday night, when Attorney General Phil Weiser, the Democratic nominee, and former U.S. Rep. Greg Lopez, an unaffiliated candidate, delved into issues of affordability, data center regulation and gun laws. The debate’s tone was civil. The policy differences between the two […]
As midterm elections approach, Republican candidates weigh how closely to align with Trump
Some Republican candidates are quietly distancing themselves from President Donald Trump ahead of the midterm elections that will determine control of Congress. Yet, most Republican candidates continue to embrace Trump
National issues continue to dominate race for N.Y. governor
Both candidates had opportunities to make their points this week.
Florence Harding Photographed Taught Me About Women Partaking in Politics
What would Florence Kling Harding think now? A week or so ago when I cast my ballot at my designated polling place this thought crossed my mind. I imagine the former first lady would be pleased about how routine voting has become for women in the United States. But perhaps she would not be satisfied. Today, a published essay I wrote for In Pursuit spotlights a lesson in leadership demonstrated by First Lady Florence Harding. In my research, I discovered there’s a lot to be said about this strong female historic figure. But it was the blurry photograph capturing Mrs. Harding voting for her husband Warren G. Harding, one of two presidential candidates from Ohio, on Nov. 2, 1920—Election Day—that drew my attention. It was the first presidential election held in the United States after the ratification and certification of the 19th Amendment, granting women the right to vote. Its 106th anniversary was marked on Wednesday. I remember thinking what a shame it was that her presence in the image was imperfect while the mostly men surrounding her were in sharp focus. Perhaps cynically I thought, “No surprise!” On further examination, though, the clear reaction of the people surrounding Mrs. Harding was equally important. In that snapshot of time, many of their expressions were serious. One man stood elevated above the rest with a slight smile as he caught a glimpse of history. Mr. Harding hovered over his wife’s shoulder closely observing the last seconds of her vote being cast. Their gazes were locked in on who would hours later become first lady. Subscribe The attention she drew is worth noting, mostly because, as I learned, Mrs. Harding understood the power her image could have on women across the country. She and I share in common a career in newspapers—hers the business side and mine on the editorial side. Nevertheless, it became clear to me as I write in the essay that she understood if she was seen voting, other women would follow suit. That wouldn’t necessarily be the case in that 1920 election, though, Karen Kedrowski, the director of the Carrie Chapman Catt Center for Women and Politics at Iowa State University, explained to me. Florence Harding was a suffrage advocate. But, suffrage was a contentious issue and women were far from united at the time of the election. In fact, a substantial number of women and active anti-suffrage organizations thought women participating in elections was a “bad idea and antithetical to their roles in the private sphere as mothers and homemakers,” Kedrowski said, adding that women were also viewed as the moral compass for their husbands and sons. If women got involved in politics they would become contaminated by it. Suffragists, on the other hand, wanted to bring that moral presence into politics to help clean things up. Only about 30% of women voted in that 1920 presidential election. That was a start. More than 100 years later in the 2024 presidential election, 66.9% of eligible women voted (91.3 million), compared to 63.7% of men who voted (82.6 million), according to the League of Women Voters. Yes, Florence Harding would be pleased. Subscribe That imperfect Election Day image was important symbolism about women’s potential during what was known as the “Modern Woman” era and the growing public role women were taking in the 1920s. I imagine Florence Harding might agree with other succeeding first ladies when it comes to gender equality and the importance of the vote. Like Michelle Obama when she said in her memoir Becoming, “We all play a role in this democracy. We need to remember the power of every vote.” Or Hillary Clinton during her unsuccessful run for president in 2016 when she remarked on International Women’s Day: “We celebrate the progress we’ve made to advance the full participation of women in economies and societies. And most importantly, we recommit to finishing the unfinished work that remains …” I hope if you are reading this, you will also read my essay on Florence Harding’s leadership lesson for In Pursuit. And perhaps that will move you to dig deeper and read more about Florence Harding’s life circumstances in biographies like First Lady Florence Harding: Behind the Tragedy and Controversy by Katherine A. S. Sibley. No, I do not think Florence Harding would be satisfied despite how far women have come from that day she first entered her polling place. She once wrote to the Camp Fire Girls, “The part that women play in the world has been greatly changed … It has been broadened and enlarged …” It has. And as women continue to engage in civics it continues to be. I imagine Florence Harding would want women to keep meeting the moment. Read the In Pursuit essay Watch on C-SPAN Share East Wing Magazine is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Subscribe
Lions coach Campbell pleased with versatility of the secondary
With training camp wrapping up on Thursday, Detroit Lions coach Dan Campbell said he loves the versatility of the secondary. There are some candidates there,’’ Campbell said on Thursday. Injuries to safeties Brian Branch and Kerby Joseph, who remain on the physically unable to perform list, opened up the competition.
Americans search for a nonpartisan politics
The two-party divide in the U.S. appears to be deepening. But the surge in independent candidates this year points to a deep desire for common ground and compromise in civic life.
Steelers CB Joey Porter Jr. named as trade candidate before NFL cutdown day
With final roster cuts looming, Pittsburgh Steelers cornerback Joey Porter Jr. has been named one of the biggest trade candidates to watch.
As data center criticism grows, focus turns to NC Senate race
The construction of massive data centers around the country has become a significant issue in the midterm elections with a growing number of political candidates taking a stand against them.
Colorado gubernatorial candidates Phil Weiser, Greg Lopez to face off Thursday in televised debate
Two of the candidates for governor of Colorado are set to square off in a televised debate for the first time Thursday night, when Attorney General Phil Weiser, the Democratic nominee, and former U.S. Rep. Greg Lopez, an unaffiliated candidate, meet in Colorado Springs. Republican nominee Victor Marx, a ministry leader and first-time candidate, declined […]
Maine candidates call for faster approvals to spark housing
Former House Speaker Hannah Pingree said the state needs to ensure that it has a trained workforce to produce more housing and that it will be important for the new governor to set a tone that housing is a critical economic need.
Party politics loom large in non-partisan Tallahassee Commission race
Tallahassee candidates PJ Perez and Tom Derzypolski are clashing over their past party affiliations ahead of the runoff.
The primaries testing Democratic 2028ers
Democrats have used their endorsements of candidates in tough primaries as a way to wield influence over the party.
5 potential trade candidates for the Dallas Cowboys
Do you think the Cowboys have any trade candidates on their team to move?
Rep. Robinson votes to crack down on corporate influence in Michigan politics
State Rep. Ron Robinson yesterday voted to get money out of politics by blocking state-regulated utilities and companies with major state contracts from donating to political campaigns and candidates. The state House overwhelmingly approved the Michiganders for Money out of Politics (MMOP) citizen-initiated law proposal, which was initiated after hundreds of thousands of Michiganders signed […]
SEE IT: LA Dem candidates torched by disgusted residents after ‘disgraceful’ debate: ‘Both bad’
Los Angeles Democratic mayoral candidates Karen Bass and Nithya Raman face voter fury after a debate one resident called "disgraceful" for the city.
Maine’s U.S. Senate race to include 6 write in candidates
If neither Republican Sen. Susan Collins nor former Democratic Maine Senate President Troy Jackson get over 50% on election night, the tallies will go to a ranked choice count.
Potential Effects of Washington Politics in Illinois Elections
Candidates this fall for statewide office in Illinois are running with national politics in the periphery. Despite not winning the state, President Donald Trump gained ground in Illinois in 2024 compared to 2020. The effect of the first half of his second term on that […]
Voter discontent abounds as third parties search for recipe to tap into it
Polls suggest voters are sick of a two-party system and Minnesota has a history of third-party success. But that doesn’t necessarily mean alternative candidates will do well this November.