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Rare founding-era documents are in LA for limited time only
Exhibition open at the USC Fisher Museum of Art from April 17 through May 3
Tavernier wants maximum points from split as Rangers target title
Rangers captain James Tavernier has set his side a title-clinching target of five wins from five after the split. The Ibrox side, who were 13 points adrift of leaders Hearts when Danny Rohl took charge in October, are now just a point off the pace. Rangers begin their post-split games at home to Motherwell next weekend while Hearts are at Easter Road for an Edinburgh derby against Hibernian and third-place Celtic host Falkirk.
They Froze a Brain to −196°C. Then Brought it ‘Back to Life’ in a Groundbreaking New Study.
Human hibernation seems like pure science fiction, but it could make interstellar travel a reality.
Cross-department collaboration brings art and science to The Bridge
A cross-department collaboration is bringing art and science together at The Bridge in ZSR Library through Botanical Bridges: Observation and Invention, a new exhibition showcasing work from Lydia Smith’s Spring 2026 Life Drawing class. An opening reception will be held on Friday, April 17, from [...]
Another big change is coming to Seattle’s Pacific Science Center
After a property sale, shuffled exhibits on campus and a round of layoffs, Seattle’s Pacific Science Center announced a leadership transition Thursday morning.
3 to See Art in Motion in Lake Worth; Norton exhibit; PB Symphony
Cultural Council for Palm Beach County recommends exploring new art exhibitions and a classical concert in Palm Beach County this week.
Tammy Baldwin targets game blackouts, expensive sports streaming apps
New legislation from Sen. Tammy Baldwin would prohibit league-owned streaming services from blacking out games and require a free option for fans.
Apple, Google Offer ‘Nudify’ Apps Despite Policies Against Them
Apple Inc. and Google have continued to offer mobile apps that let users make nonconsensual sexualized images of people despite their policies prohibiting such content, according to a report published Wednesday by the Tech Transparency Project.
Greater Wausau Chamber set to host Business EXPO Thursday
The Greater Wausau Chamber of Commerce will host hundreds of exhibitors and thousands of attendees at the organization’s annual Business EXPO on Thursday, April 16.
New Willmar entertainment venue teaming up with Rendezvous Axe Throwing
(Willmar MN-) Shining Light Entertainment at The Uptown Willmar Mall is getting closer to opening. Co-Owner Jason Miller says in addition to laser tag and mini-golf, they will be teaming up with Rendezvous Axe Throwing......Victoria Hibma of Rendezvous Axe Throwing says their location on West Litchfield Avenue is now closed and the building, which also houses an operating laundry mat, is for sale. They are in the process of moving their throwing lanes and kitchen equipment to the Shining Light location, across from Golden Ticket Cinema, in the former Chen Garden Restaurant space. Shining Light had hoped to open this past winter, but Miller now hopes to be in operation in less than 2 months......
After-hours business expo in Carteret County
Meet and greet with 65 exhibitors, take part in speed networking sessions, buy into the 50/50 cash drawing, and enjoy hors d’oeuvres, beer, and wine as you work the room.
Business of Warfighting: ONR to Boost Industry Partnerships at Sea-Air-Space
To strengthen collaboration with industry, the Office of Naval Research (ONR) — to include the Naval Research Laboratory (NRL) and ONR’s international arm, ONR Global — will host an exhibit at the Navy League’s Sea-Air-Space Exposition, April 20-22.
Dexter Lawrence trade destinations: Giants are reportedly talking with teams after extension talks get stuck with star d-lineman
Traveling mental health exhibit brings message of hope to Nazareth University
Nazareth University is aiming to communicate hope through a powerful traveling exhibit.
Greater Wausau Chamber of Commerce to host annual Business EXPO
The Greater Wausau Chamber of Commerce will host hundreds of exhibitors and thousands of attendees at the organization’s annual Business EXPO on Thursday.
New exhibitions on science of genetics, lead poisoning advocacy, on show at UAB’s Lister Hill Library
New exhibitions on science of genetics, lead poisoning advocacy, on show at UAB’s Lister Hill Library
Arctic marine science exhibition opens in Anchorage on May 15
The exhibition will include how communities and western scientists are working together, how all life in the water impacts the health of ecosystems, the importance of science communications, and intricacies of the research vessel itself.
Mid-America Science Museum opening interactive dinosaur exhibit April 25
Dinosaurs will return to Mid-America Science Museum starting April 25 with the exhibit "Expedition: Dinosaur."
Munson celebrates student accomplishments with exhibits
UTICA — Join Munson in celebrating the artistic accomplishments of their students at Pratt Munson College of Art and Design. Their work will be featured in two juried, mixed media
Dons boss Robinson will not relax until safety is secured
Stephen Robinson does not want Aberdeen to relax during their two-week break after they recorded a much-needed 2-0 win over Hibernian to boost their William Hill Premiership survival hopes. Kevin Nisbet netted from the penalty spot after Grant Hanley was sent off for hauling down Toyosi Olusanya and the Scotland striker added a second with 15 minutes to go to end a nine-match winless league run. The Dons are five points above Kilmarnock, who sit in the relegation play-off spot with five games to play, and the two teams clash at Pittodrie in the next round of Premiership fixtures which does not take place until April 25.
Pop culture takes center stage at Shenandoah Comic-Con
Warriors, robots, demons and more came out to play at Shenandoah Comic-Con at the Rockingham County Fairgrounds exhibit hall on Saturday.
"Botany of Nations" on View at The Academy of Natural Sciences Through February 14, 2027
To mark America's 250th birthday, The Academy of Natural Sciences of Drexel University has an exhibition rich with artifacts and plant specimens from the Lewis and Clark expeditions
UNA celebrates entertainment industry program's 50th anniversary with hall of fame exhibit
UNA celebrates entertainment industry program's 50th anniversary with hall of fame exhibit
Elvis and tattoos? Go inside the Memphis Tattoo Festival at Graceland
Discussions of Elvis and tattoos are inevitable this weekend, as the Memphis Tattoo Festival is held at the Graceland Exhibition Center.
Go inside Memphis Tattoo Fest at Graceland Exhibition Center
The Memphis Tattoo Festival convened for the first time at the Graceland Exhibition Center, across the street from Elvis Presley's mansion.
Public exhibit blends art, science and community knowledge
An art and science exhibit this spring at the Morris Thompson Cultural and Visitors Center in Fairbanks explores the beauty, complexity and changing nature of Alaska’s winter.
Oregon Health Authority says tattoo artists can’t use topical numbing creams, sprays
The Health Licensing Office issued a practice clarification affecting all tattoo artists in Oregon, stating that the use of topical anesthetics is prohibited and always has been.
Science fiction becomes reality at USF's Engineering Expo
At the University of South Florida’s Engineering Expo, visitors can control a robotic catapult using nothing but their thoughts. It's one of dozens of hands-on exhibits drawing thousands of students and families to campus.
North Dakotans can learn about resources to grow healthy habits on April 18 at Gateway to Health event | Health and Human Services North Dakota
Individuals and families are invited to the fourth annual Gateway to Health community event, which includes activities for all ages on Saturday, April 18, 10 a.m.- 4 p.m. at North Dakota’s Gateway to Science in Bismarck. Participants will enjoy free access to the science center during their registered two-hour time slot, along with access to interactive booths and exhibits promoting health and wellbeing through hands-on activities, games and prizes.
ARTEMIS Week Kicks off at Fleet Science Center in Balboa Park
The center is celebrating humanity’s return to deep space exploration. Visitors can explore the temporary ARTEMIS II exhibits and follow the mission as it unfolds in real-time.
Zeeland restaurant sees business boost after Sunday alcohol sales allowed
For decades, Zeeland prohibited alcohol sales on Sundays. That changed a few months ago, and one business, The Gritzmaker Social House, said the new ordinance is paying off.
Policy mitigation, human drivers and health risks of antibiotics in global aquatic environments
Communications Earth & Environment - Antibiotic contamination in global aquatic environment exhibits significant regional disparities with low-and-middle income countries experiencing higher...
Teddy bears to ticker tape: UVA Center for Politics opens new space
The expanded facility opens Friday with an exhibit of historical campaign memorabilia, from Washington to Trump.
Texas Hemp Businesses Sue State Over Rules That ‘Rewrite Law’
The Texas Hemp Businesses Council and other industry stakeholders are hoping to block the state from enforcing new rules that prohibit popular products.
Nuclear Science Trailer at Wyoming Schools, Public Reception to Accomp
The Nuclear Energy Emerging Issue Forum will feature a public reception with interactive exhibits about nuclear industries Monday, April 13, from 4:30-6:30 p.m.
Governor signs bill expanding who can petition for weapons restrictions
Gov. Jared Polis on Monday signed a bill into law expanding who can ask a judge to temporarily restrict a person’s access to firearms. Established in 2019, 0Colorado’s extreme risk protection law (ERPO) initially allowed a family member or law enforcement officers to petition a court to prohibit an individual they believe poses an “imminent […]
Interactive exhibits shine at IMAG History & Science Center in Fort Myers
Gulfcoasting takes you inside IMAG with Jason Drew and Director Christian Gould — exploring interactive science, the Gulfcoast Weather Experience, and the outdoor estuary where longtime animal residents steal the show.
AMC Entertainment Delivers Best Ever Global Revenue Mark for a 5-Day Easter Weekend, Led by THE SUPER MARIO GALAXY MOVIE, Strong Merchandise Sales, and Solid Performances by Other Titles
AMC Entertainment (NYSE: AMC), the largest theatrical exhibitor in the United States and in the world, today announced that it delivered a record-setting per...
AMC Entertainment Delivers Best Ever Global Revenue Mark for a 5-Day Easter Weekend, Led by THE SUPER MARIO GALAXY MOVIE, Strong Merchandise Sales, and Solid Performances by Other Titles
LEAWOOD, Kan., April 06, 2026--AMC Entertainment (NYSE: AMC), the largest theatrical exhibitor in the United States and in the world, today announced that it delivered a record-setting performance over the 5-day Easter holiday weekend, achieving the highest combined global admissions and food & beverage revenue for the holiday frame in AMC’s 106-year history.
Art and politics … intersecting again
The stunning ”Resistance” Mexican art exhibit at the New Bedford Art Museum is unpredictable and necessary.
OH WOW! Science Center will host interactive, augmented sandbox exhibit
OH WOW! The Roger & Gloria Jones Children’s Center for Science & Technology will host an interactive, augmented exhibit beginning Monday, April 6, 2026.
See a 360-degree view of the American Revolution at this new French Quarter exhibit
The HistoPads are back at the Historic New Orleans Collection — hand-held tablets that act as a portal to 360-degree views of the sites and events depicted in “American Revolution:
Bandai Namco Entertainment Booth Report From AnimeJapan 2026! Exhibits Including New SAO Action Game Echoes of Aincrad and New Illustrations by abec
AnimeJapan 2026, one of Japan's largest anime events, was held at Tokyo Big Sight on Saturday, March 28 and Sunday, March 29, 2026. In this article, we report on the Bandai Namco Entertainment booth at this event!
New cases of a deadly bacterial disease alarm doctors
The Hib vaccine drastically cut cases of a once feared contagious disease. New cases in unvaccinated kids feed concern that Hib may have a resurgence.
Apple debuts 50th anniversary exhibit at Apple Park with iconic products and photography
Apple debuts 50th anniversary exhibit at Apple Park with iconic products and photography.
Democrats rebounding without learning necessary lessons
“When we fight, we win!” That, reportedly, was the chant heard over and over again at the Colorado Democratic Assembly a week ago. It suggests that pugilism has been the piece missing from the Democratic toolkit. Perhaps it was just me, but I seem to recall Democrats exhibiting plenty of fight back in 2024. The […]
Annual Santa Fe Chamber of Commerce Business Expo planned for Thursday
Roughly 120 exhibitors and more than 1,000 attendees are expected for the expo at the Santa Fe Community Convention Center.
Downtown Lancaster celebrates 1st First Friday of spring [photos]
Those in downtown Lancaster were able to celebrate spring's first First Friday event for 2026 this Friday. There were plenty of new exhibitions to check out, as well as concerts
We the People: Truman Library scores with new sports exhibit
The highlights include Lamar Hunt’s ticket to the first game at Arrowhead Stadium, a football signed by Len Dawson and a baseball bat gifted to President Ronald Reagan after the Royals won the 1985 World Series.
Manchester’s SEE Science Center celebrates 40 years of education, outreach and fun
Adam Irvjo of Westerly, Rhode Island, and his son Grayson, 3, check out an interactive exhibit on pulleys at the SEE Science Center in Manchester on Tuesday.
An Art-Science Partnership Offering New Views of Dynamic Landscapes
The immersive and interactive WILDLAND exhibition allowed the public—and the exhibition’s creators—to explore connections among water, trees, fire, and other natural and human-made materials expressed…
Killie players 'needed a telling off', says Deas
Robbie Deas says Kilmarnock players "needed a telling off" to help turn around their form this season. Killie travel to face Hibs on Saturday with the chance to exit the relegation play-off spot following their back-to-back wins over Livingston and table-toppers Hearts before the international break.
New Mexico Museum of Natural History and Science Reopens April 4 with Traveling Exhibition
"Animal Armor: The Evolution of Armor in Dinosaurs and Prehistoric Animals" puts the spotlight on armored animals and the history of the evolution of armor in prehistoric creatures.
A deadly bacterial disease is returning, doctors warn, as vaccination rates fall
Hib once killed 1,000 children a year, permanently disabling many more. Doctors who've never seen the disease say the comeback is changing the way they practice medicine.
Artists' Cooperative to host 31st annual 'Regional Art Exhibit'
WESTERLY — Peter Geisser, former art director at the Rhode Island School for the Deaf, is serving as guest juror for The Artists’ Cooperative Gallery of Westerly's annual "Regional Art
Texas judge rejects push to let churches make political endorsements
A group of Texas churches and the IRS agreed to nix the Johnson Amendment, which prohibits nonprofits from endorsing candidates. A Trump-appointed judge said no.
'Pieced Together': Art show features traditional, unique quilt designs
A new exhibit called “Pieced Together” at Skull City Studio showcases 28 quilts by 14 artists, blending traditional American quilting with diverse and lesser-known styles to highlight the craft’s creativity
Entertainment and more in the Mid-Ohio Valley
PARKERSBURG – The Artsbridge calendar for the week: TODAY * Geppetto Woodcarver’s Wood Quilt display, 9 a.m. to 4 p.m., WesBanco, Market Street, Parkersburg WEDNESDAY * Diane Wigal wildlife photography exhibit, 9 a.m. to 4 p.m., WesBanco, Market Street, Parkersburg * Story Hour, ages 3-6, 10-11 a.m., Marietta Public Library * Bookworms Storytime, ages 3 […]
Trump administration sues Minnesota for allowing trans athletes in girls’ sports
Justice department claims the state is violating Title IX – the federal law that prohibits sex-based discrimination
A $1,000 PS6 And Xbox Helix Are Dangerous For The Future Of Gaming
At a certain price, consoles are so expensive that they are totally prohibitive for average players. We may be there in the next generation.
A Legacy of Valor; Virginia Air and Space Science Center opens new Tuskegee Exhibit
HAMPTON, VA – U.S. Air Force Gen. Adrian Spain, commander of Air Combat Command, joined U.S. Army Air Forces Sgt (former) Thomas Newton, Documented Original Tuskegee Airman, and others in cutting the ribbon of the new exhibit on Mar. 26, 2026, officially cementing the legacy of the Tuskegee Airmen at the VASSC.
Maine Science Festival brings in the next generation with interactive exhibits
WABI TV5 News at 4
Floyd Mayweather reveals Manny Pacquiao rematch will be an ‘exhibition’
The pair are set to resume their rivalry in September but Mayweather has cast doubt on whether this bout will be his return to professional boxing
Science, mapping and art collide at ArtReach
A river story unfolds at ArtReach St. Croix with the opening of two exhibitions, Deep Mapping and Valley Pottery: 2,000 Years. Both exhibitions show a deep love for the valley
Floyd Mayweather pumps brakes on rematch with Manny Pacquiao
Floyd Mayweather cast some doubt on details of his pending fight with Manny Pacquiao, saying the location has not be set and that the bout will actually just be an exhibition.
Maine Science Festival brings in the next generation with interactive exhibits
Maine Science Festival Exploration Stations brought the next generations of scientists together in Bangor.
Seattle Art Museum considers influences of celebrated Northwest Mystics
The Seattle Art Museum exhibit "Beyond Mysticism" traces the pulsating throughline that connects artists from the midcentury to the city’s contemporary artists.
Science Museum of Virginia offers hands-on animal encounters and maker workshops
Visitors can explore Animal Lab exhibits and create projects in the Forge workshop space.
Treasury plans to put Trump's signature on all new U.S. paper currency in break with tradition
The plans come in tandem with an ongoing effort to get Trump’s face on a coin, which has also drawn criticism since federal law prohibits the depiction of a living president on U.S. currency.
Apple Sends Lock Screen Alerts to Outdated iPhones Over Active Web-Based Exploits
Apple issues Lock Screen alerts after Coruna and DarkSword exploit kits target iOS 13.0–18.7, increasing web-based attack risks.
87-year-old planetarium projector still dazzles visitors at Springfield Science Museum
The device is not only a technological marvel, but could easily be an exhibit in the very museum where it remains in operation.
University Park officials say SMU crosswalk doesn't violate state order
University Park officials say an intersection featuring the Southern Methodist University mascot is not in violation of Texas Gov. Greg Abbott’s order prohibiting decorative markings on state roads.
Sun, sand and science: kick start your summer at the Royal Society Summer Science Exhibition
The Royal Society Summer Science Exhibition returns for 2026, from 30 June to 5 July, with everything you need for a sensational summer in the heart of central London.
Scientists discover why cancer drugs don’t work for everyone
Scientists have uncovered a hidden reason why cancer treatments don’t work equally well for everyone. Certain drugs can become trapped inside lysosomes within tumor cells, forming slow-release reservoirs that create uneven drug distribution. This means some cancer cells are heavily exposed while others are barely affected. Understanding this process could help doctors better tailor treatments and improve outcomes.
Record-Breaking NBAA SDC2026 Powers Business Opportunities and a Bold Vision for the Future
A record-setting 3,500 attendees had an opportunity to see the full range of leading products and services on a sold-out exhibit floor over two business-driven days that also featured inspiration, innovation and powerful in-person connection at every turn throughout the 2026 NBAA Schedulers & Dispatchers Conference (SDC2026) in Cleveland.
AAN Art from the Schools at Johnson Gallery
The Artists Association of Nantucket kicked off its annual Art from the Schools exhibition of work by island students in grades six-12 with an opening reception and the presentation of
House Democrat bans staff from betting on prediction markets, citing ethics concerns
Democratic Rep. Seth Moulton of Massachusetts has prohibited staffers from betting on prediction markets on areas such as politics and any information obtained in an official capacity.
Trunk show: Elephants roam the human imagination in EcoTarium exhibit
Elephants are a study of grace, beauty and strength, but they face threats, mainly from humans. An exhibit at the EcoTarium their world, and ours.
New ‘Prehistoric Wisconsin’ exhibit features items from the former Weis Earth Science Museum
The exhibit is located at the History Museum at the Castle in Appleton.
Fathom Entertainment CEO Ray Nutt to Retire; Search for Replacement Underway (EXCLUSIVE)
Specialty distributor Fathom Entertainment announced Wednesday that CEO Ray Nutt plans to step down from the company and retire later this year. Nutt, an exhibition vet who has served as chief executi...
Glyphosate: A story of science, risk, and nuance
In the summer of 2014, a California groundskeeper named Dewayne Johnson started noticing patches of raw, weeping skin spreading across his body. He had spent years applying Roundup, Monsanto’s glyphosate-based herbicide, for a school district, sometimes drenched in it when equipment malfunctioned. By 2014, he had a diagnosis: non-Hodgkin’s lymphoma. In 2018, a jury awarded him $289 million in damages, later reduced on appeal. Tens of thousands of lawsuits followed. The story hasn’t quieted down. It’s all over the internet, swinging between “this will kill you, buy organic” and “relax, you’re fear-mongering.” Some of that recent chatter stems from an Executive Order protecting glyphosate and its production, which set off intense infighting within the MAHA movement. Some of it reflects a deeper truth: Americans genuinely care about harmful chemicals in their environment (see poll below). And the conversation isn’t going anywhere, with a Supreme Court case involving Monsanto set for this April. Glyphosate (the active ingredient in Roundup) is one of the most widely used herbicides in the world. But does glyphosate cause cancer? And how much exposure is actually risky? With so much mistrust in institutions and corporations (and some genuine conflicts of interest), making sense of the actual scientific evidence is genuinely hard. Here is a translation of what the scientific evidence actually says. Does glyphosate cause harm? Glyphosate is an herbicide that kills most plants it contacts rather than targeting specific species. It works by blocking an enzyme pathway (EPSPS) that plants and many microorganisms need to produce essential amino acids. Without those amino acids, the plant can’t grow and dies. Glyphosate was first developed by Monsanto in the 1970s and became ubiquitous after the company introduced “Roundup Ready” crops in the 1990s. In 2024, Bayer removed glyphosate from residential Roundup-branded products due to litigation pressure. But today it is still the most widely used herbicide in the world. Farmers also discovered they could spray it directly on crops like oats, lentils, beans, and peas just before harvest to dry them out faster and make harvesting easier. Because of its widespread use, it’s obviously really important to understand if it’s harmful to humans. The key principle: The dose makes the poison The most important concept in toxicology is that “the dose makes the poison.” Sixteenth-century physician Paracelsus articulated what remains the foundational principle of toxicology: sola dosis facit venenum. Water will kill you if you drink enough of it. Aspirin saves lives at 81 milligrams and causes internal bleeding at higher chronic doses. So, at what dose is glyphosate poisonous? The LD50 in rats (the dose that kills half the test animals) is around 5,600 mg/kg body weight. Table salt is roughly 3,000 mg/kg. By that classic measure, glyphosate is less acutely toxic than salt. But some people are exposed to a lot of glyphosate through their work. And among the general public, there are many questions about low-dose, cumulative exposure from multiple sources over long periods. Does glyphosate cause health problems? Cancer Correlation maps are striking, with one analysis finding that 60% of counties that spray the most glyphosate have non-Hodgkin’s lymphoma rates above the national average. But correlation alone doesn’t establish cause, which is why animal and human studies matter. In animals: Rat studies are typically what most fear is rooted in, but most people don’t know the study details on the dosage given to rats. A pooled analysis of the 13 most rigorous rat studies found evidence that very high doses, around 55,000 times greater than typical food residue exposure, can cause certain cancers. In humans: One of the strongest studies followed 55,000 herbicide users over 20 years and found no overall increased cancer risk. There was one signal: among those with the highest use, rates of acute myeloid leukemia (AML) appeared elevated. A broader meta-analysis of 18 human studies also found no overall cancer risk, though a separate meta-analysis focused specifically on non-Hodgkin lymphoma found that people with high cumulative glyphosate exposure faced a 41% higher relative risk compared to those with low or no exposure. These human studies are observational studies (randomized controlled trials would be unethical), and meta-analyses are only as reliable as the studies they pool. But the story seems consistent: at very high exposure levels, there may be some cancer risk. But that’s about as far as the science currently takes us. Emerging research: gut and reproductive health Gut: Because glyphosate targets a pathway that exists in some gut bacteria, scientists have questioned whether it could affect the microbiome. In mice, a 2023 University of Iowa study found that glyphosate altered gut bacterial composition and raised markers of intestinal inflammation. A 2024 systematic review found similar patterns: disrupted gut bacteria and problems with the mucus layer that protects the intestinal wall in mice. Whether this translates to humans is an open question. The human gut is highly variable and resistant, and we don't yet have strong studies confirming the same effects in people. Reproductive health: Animal studies have found that glyphosate-based herbicides can interfere with reproductive hormones, including disrupting egg cell development in mice and reducing the number of eggs available in sheep’s ovaries. However, the doses used in these experiments were high, so it’s not yet clear whether the same effects would occur in humans. On the human side, a 2021 pilot study led by Mount Sinai researchers tested urine samples from pregnant women across the U.S. and found glyphosate in 95% of them. The study also found a possible connection between higher glyphosate exposure during pregnancy and a subtle physical difference measured in female newborns. That said, some connections weren’t statistically reliable and this was a small study. The researchers themselves said more and larger studies are needed before drawing firm conclusions. What do regulators say about glyphosate safety? In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization, classified glyphosate as "probably carcinogenic to humans" (Group 2A). The classification is worth taking seriously. But, there’s an important distinction: IARC classifies hazard, meaning the potential to cause harm under some conditions. It does not assess risk, which accounts for actual exposure levels and the real-world probability of harm. The U.S. EPA, the European Food Safety Authority, Health Canada, and regulatory agencies in Australia and Japan have all concluded that glyphosate is “unlikely to be carcinogenic to humans” at realistic exposure levels. They’re asking a different question: given how much of this people actually encounter, what is the probability of harm? Your actual exposure is what determines your actual risk. What does glyphosate mean for your daily life? At the grocery store: Food residues are small. The EPA’s acceptable daily intake is 1.75 mg/kg of body weight per day. To hit that threshold from oatmeal alone, a 150-pound adult would need to eat roughly 50 pounds of oats every day. But this calculation addresses only one pathway (food), and we don’t yet have robust tools to measure people’s actual total exposure. If reducing exposure matters to you, organic certification prohibits synthetic herbicides, and organic oat products generally test at lower or undetectable levels. Either way, a diet rich in whole grains, conventional or organic, is far better for your health than one that omits them out of fear of residues. On the farm: Occupational exposure is orders of magnitude higher than consumer exposure. Farmers and farm workers who mix, load, and apply glyphosate-based herbicides, especially without protective equipment, face meaningfully different risk profiles. Proper PPE isn’t optional. Integrated weed management strategies that rotate chemical modes of action are also worth taking seriously, both for health and for long-term effectiveness. If you live near a farm: Spray drift is real. Concentrations near field edges can spike during and after application, particularly on windy days. This is an area where I think public health could really step up and empower rural communities with buffer zones, rather than placing the onus on individuals. But for now, knowing your local agricultural calendar and keeping windows closed during application are the first steps. Bottom line Dewayne Johnson was exposed to glyphosate at levels most people will never encounter, and a jury decided he deserved compensation. That outcome is not evidence that the oatmeal in your pantry is dangerous. But it is a reminder that the dose, the context, and the person doing the exposing all matter enormously. Glyphosate is a chemical tool with benefits, trade-offs, and genuine open scientific questions. Learning to hold that complexity without collapsing into panic or dismissal is, honestly, one of the most useful and hardest things to do in navigating modern health science. Love, YLE Your Local Epidemiologist (YLE) is founded and operated by Dr. Katelyn Jetelina, MPH PhD—an epidemiologist, wife, and mom of two little girls. Hannah Totte, MPH, is an epidemiologist and YLE Community Manager. YLE reaches more than 425,000 people in over 132 countries with one goal: “Translate” the ever-evolving public health science so that people will be well-equipped to make evidence-based decisions. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe
Maine Science Festival returns to Bangor for 11th year
The five-day festival is free to attend and will include over 70 activities in the Bangor area for all ages including workshops, presentations, and exhibits.
12 Life Science Startups Named to SLAS Europe 2026 Innovation Showcase Program
SLAS has named the 12 companies selected to participate in its Innovation AveNEW program at the SLAS Europe 2026 Conference and Exhibition.
Freeway series game II chat
The Dodgers play their first game at Dodger Stadium since Game 5 of last year’s World Series on Monday, hosting the Angels for the second of a three-game exhibition series. Roki Sasaki goes for the Dodgers against left-hander Reid Detmers. MONDAY GAME INFO
Data centers under scrutiny by California lawmakers as fears rise about health and energy impacts
Due to health and energy concerns, the California Legislature is considering bills to prohibit data centers from being exempted from the state's stringent environmental law and impose new tariffs on new major energy users that strain power supplies.
Exclusive | Lawmakers to Introduce Bipartisan Bill Banning Sports Bets on Prediction Markets
A bipartisan pair of U.S. senators are introducing legislation to prohibit CFTC-regulated entities from listing contracts related to sporting events.
River Cats top Giants in exhibition at Sutter Health Park as fans welcome baseball’s return
"Finally, the drought is over between football and the start of baseball."
A promising fatty liver treatment may raise cancer risk
A surprising new study reveals that blocking a supposedly protective enzyme, Caspase-2, could actually backfire—raising the risk of chronic liver damage and cancer over time. Researchers found that without this enzyme, liver cells grow abnormally large and accumulate genetic damage, leading to inflammation, scarring, and eventually tumors, especially with age. While inhibiting Caspase-2 may offer short-term benefits, such as reducing fatty liver disease, the long-term consequences appear dangerous.
Nevada Wins Temporary Ban on Sports Betting on Kalshi
The prediction-market platform must obtain state gambling licenses and prohibit users under 21 to offer such contracts, a state court said.
Your Thymus and Your Healthspan
Our thymus gland plays a central role in the development or our immune system, specifically for supporting T cell development (how these cells got their name, maturation and differentiation in the thymus) and discriminating between self and foreign, non-self antigen proteins with production of dendritic cells. As we age, our thymus gland shrinks—the process known as involution—with progressive change from spongy to fatty tissue, with loss of functionality. But this process, with respect to timeline and extent, markedly varies from one person to the next. And to make things even more complicated, our thymus gland anatomy and precise location in the chest also is highly variable. So the famous Frank Netter diagrams from the 1960s (such as at left below) don’t capture the remarkable heterogeneity that a random set of 12 chest CT scans (below at right). What I consider as 2 landmark papers in Nature this week (here and here) used AI to quantify health of the thymus in 2 large cohorts, and then correlate the metric to a broad array of health outcomes. In this edition of Ground Truths, I’m going to cover three questions: (1) How was thymus health determined by AI?; (2) How is thymus health linked to key clinical outcomes? and (3) Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? Subscribe 1. How was thymus health determined by AI? This was accomplished by extensive work developing and validating an AI pipeline for 2 stages, the first for localization and segmentation of the thymus bed, and the second to quantify a digital marker, termed the thymic health score. There’s a lot to this algorithmic development, so I won’t go into all the details, but just provide a rudimentary outline of what was done. The 1st stage used supervised learning with 2 radiologists reviewing 2,461 chest CT scans. That work trained a 3D U-Net model to automatically identify the thymic bed’s 3D cropped region using center of mass coordinates, which reached 99.8% accuracy. The 2nd stage used a foundation model that was pre-trained with SwAV (which stands for Swapping Assignment between multiple Views), a self-supervised model, that generated a high-dimensional thymus representation of 4,096 features. That compares to the radiology reductionist and subjective scoring of 0 to 3 where 0 means the thymus is fully degenerated and fatty, and 3 is considered dense, intact glandular soft tissue. Notably, the self-supervised learning (SSL) performance was superior to supervised (AUC ~0.75 vs 0.55, respectively) reflecting the shallowness of the 0-3 classifier vs SSL’s holistic, self-taught AI. The thymic health score ranged from 0 to 100, with the highest number indexed to fully preserved thymic health. The algorithmic work extended to explainability with both Shapely value distribution, meaning the model was holistic not relying on any “magic” pixel, and occlusion sensitivity, demonstrating the model’s performance was not affected by ribs, sternum, lung tissue, but rather focused on the thymic bed directly. Below are a few saliency maps from the occlusion sensitivity that indicate the thymic bed focus, not affected by neighboring structures, using the jet color scale. Now the AI was ready for processing ~25,000 CT scans, each over 30 MB files, from the 2 large participant cohorts to provide a thymic health score, it did so in less than 14 hours, which is less than 2 seconds per scan! Share 2. How is thymus health linked to key clinical outcomes? The two cohorts were the National Lung Screening Trial, NLST (N=25,031) and the Framingham Heart Study, FHS (N=2,581) each with baseline demographics and long term follow up of >12 years for health outcomes. From the NSLT, you can see below that increased age and body-mass index were correlated to reduced thymic health. And, overall, men had reduced thymic health scores compared with women. There are a lot of graphs in the paper for outcomes, for both the NLST and FHS cohorts. To simplify the major outcomes, below is a composite Figure with striking reduction of all-cause mortality and for the different causes of death. The results were consistent between the 2 cohorts. For example, the cardiovascular mortality hazard ratio average was 0.57 in NLST and 0.38 in FHS (weighted to be 0.53 for the aggregate). The reduction of mortality also extended to digestive diseases and pulmonary disease (data not shown below). Lung cancer incidence was reduced by 36% for high vs low thymic health (Figure below, with a panel -incidence and b panel-mortality, adjusted for age, sex, BMI, smoking status). Notably, there was a smoker’s paradox: lower incidence and improved survival for lung cancer in smokers who had a high thymus health score. Smoking was associated with lower thymic scores whereas alcohol was not. Higher thymic health was linked to higher HDL cholesterol, lower triglycerides, lower fasting blood glucose, and lower systolic and diastolic blood pressure. Inflammation biomarkers, such as C-reactive protein and interleukin-6, were elevated in the people with lower thymic health scores. In their second paper, the same team looked at the relationship between thymic score and outcomes for 3,476 patients receiving cancer immunotherapy. The non-small cell lung cancer progression-free survival was reduced in patients with low thymic health score. A parallel relationship for survival was seen for other types of cancer including melanoma, breast, and kidney with a 44% lower risk among high thymic scores (Figure). A similar pattern was seen with different immune checkpoint inhibitors. The thymus health score outperformed programmed death ligand-1 (PD-L1)and tumor mutation burden (TMB) assay of the tumor and was an independent prognostic marker of progression-free survival. In this dataset, a direct connect with thymus score and adaptive immune function was noted with a correlation before cancer treatment for both T-cell diversity and thymus T-cell production (a metric known as T cell receptor excision circles). Thymus Removal Study There is a highly relevant citation about thymus function before moving onto ways to rejuvenate it. In 2023, a very important study of thymus removal during cardiothoracic surgery was published, with 1146 patients undergoing thymus removal vs 1146 matched controls (mean age 55 years). The adverse outcomes for thymus removal were striking, with a 2.9 higher risk of all-cause mortality and doubling of cancer incidence, 1.5 fold increase in cancer mortality, and 1.5-fold increase in autoimmune diseases. The immune function showed marked compromise after thymus removal, as reflected by CD4+ and CD8+ T cells (Figure below) Share Ground Truths 3. Are there ways we can promote a healthy (aka rejuvenate) thymus gland in our later years? In recent months we’ve learned a lot about the process of thymus involution and the pathways by which this may be modulated. Thymus involution is primarily due to loss to thymus epithelial cells (TECs) and there are 2 subtypes with different functions: the cortical, responsible for positive selection of T cells, and the medullary, for negative selection. When adipose tissue infiltrates the thymus, thymic adipocytes are pro-inflammatory, knocking out T-cell output. Likewise, systemic inflammation, or “inflammaging,” from smoking, obesity, and chronic stress promote thymic adipocytes. Now, from preclinical studies, we know about key pathways that account for these processes. Historically, back in 2014, FOXN1 was recognized as a single master transcription factor essential for TEC function, with studies in mice with forced FOXN1 upregulation leading to thymus regeneration. That laid the foundation for potential regrowth of quiescent thymus cells. It took awhile to find pathways to accomplish this goal and to even refute its role as the master regulator. The Liver-Thymus Axis Feng Zhang and his team recently showed that injection of an mRNA vaccine to the liver encoding DLL1, IL-7 and FLT3-L in combination, factors known to support thymopoiesis (Figure), successfully enhanced immune function in aged mice. However, the effect was transient. The FGF21 Story Two reports in 2025 addressed the thymus gland’s production of FGF21, a growth factor (fibroblast growth factor 21) and its control of thymus involution. This growth factor is also produced by the liver, but it doesn’t have impact on the thymus in aged rodent models. In contrast, The liver’s hepatocyte growth factor (HGF) has been shown to reverse senescent TEC structural changes. Growth hormone stimulates production of insulin growth factor-1 (IGF-1) in the liver and the thymus. Two small studies in human participants (TRIIM, for Thymus Regeneration, Immunorestoration, and Insulin Mitigation) of 6 and 50 people, respectively, treated with combined human growth hormone, metformin and DHEA, suggested the potential of slowing epigenetic aging and improving thymus mass and function. But the combination of drugs, small sample, and lack of controls make conclusions murky. Increased thymus FGF21 led to increased CD8 T cells in old mice and extended healthspan and improved physical performance. Building on the previous FOXN1 data, ablation of β-klotho, the obligatory co-receptor for FOXN1, accelerated thymic aging. The benefit to FGF21 was confirmed in a companion paper using an FGF21 knock-in mouse model showing thymus enlargement and increased TECs throughout the lifespan. (schematic Figure below). The accompanying editorial for these 2 papers speculated: “The proposed link between age-associated thymus involution and organismal aging is intriguing, and suggests we might seek to achieve systemic rejuvenation by counteracting thymic involution.” Other Factors Lessons from the Axolotl (Mexican Salamander) In an elegant set of experiments of the axolotl (Figure), known for its complete thymus regeneration after total surgical removal, mediators were identified. Surprisingly FOXN1 was dispensable. But midkine, a growth factor, appeared to be the driver, the initiator of thymus cell growth, survival, and repair. Other components that contributed were Postn+ (periostin-expressing mesenchymal niches) and Ccl19, a chemokine protein from the bloodstream. RANK and RANKL RANK (receptor activator of nuclear factor κB its ligand (RANKL) have been considered key regulators of medullary TECs. In a study of both aged mice and human thymus cell cultures, their key role was confirmed, with multiple benefits of resorting TEC function, recruitment of progenitor cells, and T cell development. Subscribe Summing Up This body of work strongly supports the health of the thymus gland as a critical regulator of human healthspan, not just a correlate or link. The new landmark studies are reinforced by the regenerative biology experimental models that have shown, via an array of mediators, that healthspan of aged mice is at least in part dependent on thymus gland function and its critical role for maintaining adaptive immunity. It sure seems that we’d be better off having an immune reservoir of naive T cells instead of a profile in older adults of exhausted, low quality, memory T cells, with a senescent phenotype. It is striking that we ignored the importance of the thymus gland for many decades. A wake-up call was the results of the thymectomy matched control study reviewed here, with the opposite of high thymic health score improved health outcomes. The convergence of AI and healthspan here is notable. The exceptional and laborious work for developing and validating (no less explaining) the AI to quantify thymus health set the foundation for probing the connect the major health outcomes in two cohorts with extensive follow-up. We’ve never had a way to meaningfully quantify the thymus gland before, so this represents important leverage of supervised, self-supervised, and transformer models. The study wouldn’t have been possible without AI. And it begs the question as to whether there are ways we can maintain our thymus at a high health score. But it’s not so simple to rejuvenate our thymus. There are multiple risks including the induction of autoimmunity, increasing the risk of cancer, and inducing a pro-inflammatory state. For example, factors that increase TEC proliferation could compromise the medulllary negative selection process and leak out auto-reactive (self-attacking) T cells. Thymic cells could be induced to proliferate, but we know, for example, that growth hormone and IGF-1 are associated with an increase risk of cancer. If thymus rejuvenation doesn’t clear out the accumulated senescent cells in older adults, then inflammation within the gland could block the production of TECs. Keeping these risks in mind, we now have identified many ways to keep our thymus healthy as we age that undoubtedly will be tested in clinical trials going forward. Ultimately, the benefit-to-risk tradeoffs will be defined. In the meantime, we have desperately needed an immunome. As I’ve stressed in multiple prior Ground Truths, we have no test in the clinic to assess a patient’s immune status! It was very encouraging for me to get an email from Hugo Aerts, the senior author of the landmark papers in the days after they were published: “I also wanted to say that your Substack on “Why We Need an Immunome” was inspiring for this work. We found it a very compelling perspective and greatly enjoyed reading it.” Just having an assessment of a person’s immune status via a chest CT scan, with millions of these performed per year, might help in guiding the right immunotherapy for cancer (e.g. more intensive, combinations for those with low thymic health scores) and help define people who are increased risk for age-related diseases of cancer, cardiovascular, and neurodegenerative. The main theme of Super Agers is that we now have many layers of data (genetics, proteins, biomarkers, organ clocks that can be integrated via multimodal AI) for us to define a person’s specific risk decades before one of these age-related diseases leads to symptoms, enabling prevention. From the new studies this week, we can add thymus health score as yet another way to understand a person’s risk, a window into their adaptive immune system and healthspan. And perhaps someday we will be able to safely rejuvenate the thymus, or maintain its health through one’s life, and use the thymus health score to monitor. NB: I wrote this post (No A.I.) A Quick Poll Loading... ********************************************************************* Thanks to Ground Truths subscribers (now > 200,000) from every US state and 212 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile. Please join! If you found this interesting PLEASE share it! Share Ground Truths Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don’t hesitate to post comments and give me feedback. Let me know topics that you would like to see covered. Leave a comment Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. 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