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AI, Ethics and Business Collide in Anthropic’s Standoff with the Pentagon

Marc Ruggiano, director of Darden’s LaCross Institute for Ethical Artificial Intelligence in Business and a navy veteran, shares his insights on the clash between Anthropic and the Pentagon and explains how Darden teaches students to navigate the often choppy waters of business, ethics and technology.

news.darden.virginia.edu logo
Feb 27 • 3:59 PM EST • Business • news.darden.virginia.edu
Trump just found the worst way to regulate AI

The real danger in Trump’s crackdown on Anthropic’s newest AI model.

vox.com logo
Jun 16 • 6:00 AM EDT • Politics • vox.com
Anthropic’s Claude Science bets on workflow, not a new model, to win over scientists

Anthropic's Claude Science is a workbench that gives scientists one environment to do computational research, saving them from the need to bounce between databases, pipelines, and tools.

techcrunch.com logo
Jun 30 • 1:00 PM EDT • Science • techcrunch.com
Claude launches Google Docs, Sheets, and Slides integration with sidebar and more

If Gemini isn’t quite your cup of tea, Anthropic’s Claude now supports sidebar integration with Google Docs, Sheets, and Slides....

9to5google.com logo
Oct 6 • 3:10 PM EDT • Technology • 9to5google.com
Anthropic’s latest Claude release turns your Mac into a small business powerhouse

If you run a small business from your Mac, you’ll want to pay attention to Anthropic’s latest Claude release. Claude...

9to5mac.com logo
May 13 • 3:30 PM EDT • Business • 9to5mac.com
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Federal appeals court rules Pentagon’s blacklist of Anthropic was legal

The Department of Defense can blacklist Anthropic’s artificial intelligence technology, a federal appeals court ruled on Friday. The decision is a blow to Anthropic after it won a separate challenge in a California court in August that partially invalidated the Trump administration’s label.

cnn.com logo
Sep 25 • 5:02 PM EDT • Business • cnn.com
The Fable 5 AI Model Just Went Dark. What the US Government’s Playbook Means for AI Companies—and Every Business Leader

Anthropic’s newest AI went dark just three days after launch. What happened next offers a stark warning for any CEO facing a powerful adversary.

inc.com logo
Jun 14 • 1:10 PM EDT • Business • inc.com
Researchers say Anthropic’s Claude Science will boost drug discovery

Anthropic's Claude Science aims to speed up drug discovery. Northeastern scientists weigh in on what it could mean for their research.

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Jun 30 • 6:08 PM EDT • Science • news.northeastern.edu
Anthropic’s Political Risks Are Real, but OpenAI’s Loom Even Larger

The U.S. government’s targeting of Anthropic might not last—especially if political winds shift.

wsj.com logo
Jul 8 • 5:30 AM EDT • Politics • wsj.com
AI Is Running Laps Around Our Political System

The technology is moving faster than elected officials can handle—and Anthropic’s CEO says the industry should slow down.

theatlantic.com logo
Sep 12 • 2:32 PM EDT • Politics • theatlantic.com
Google is about to release a new Gemini model

Sources say that Google plans to announce a new Gemini model at its annual I/O conference on Tuesday. I’m told the release will land roughly in the class of OpenAI’s recent GPT-5.5. and well short of Anthropic’s Mythos, which, despite not being widely available, has reset how every lab talks about what “leading” means.

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May 13 • 10:12 PM EDT • Technology • sources.news
Anthropic’s new Claude feature is quietly selling you on AI

Claude’s new Reflect dashboard doesn’t just visualize how you use AI. It also subtly reinforces how much of your daily work now depends on Anthropic’s chatbot.

techcrunch.com logo
Jul 9 • 10:53 AM EDT • Technology • techcrunch.com
How Anthropic’s Mythos has rewritten Firefox’s approach to cybersecurity

Security researchers at Mozilla say Anthropic's Mythos has unearthed a wealth of high-severity bugs in Firefox.

techcrunch.com logo
May 7 • 12:05 PM EDT • Technology • techcrunch.com
Claude Cowork expands to mobile and web

Anthropic’s Claude Cowork is now available on web and mobile for Max subscribers. Until now, Cowork largely lived on a user’s laptop. With the update, users can start a task from their desk, get status updates on their phone, and pick up the finished output later — even if their laptop is closed.

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Jul 7 • 12:27 PM EDT • Technology • techcrunch.com
Pentagon Casts Cloud of Doubt Over Anthropic’s AI Business

Anthropic PBC started this year on a winning streak, with surging sales, multiple viral products and a large funding round all giving the startup a big advantage in the costly global AI race.

bloomberg.com logo
Feb 27 • 9:40 PM EST • Business • bloomberg.com
AI models that can take down governments and business months away, rare Five Eyes statement warns

Signal agencies in Australia, the US, the UK, New Zealand and Canada sound alarm after Trump blocks foreign nationals from Anthropic’s Fable AI model

theguardian.com logo
Jun 22 • 9:00 AM EDT • Business • theguardian.com
Washington’s Scramble to Get Mythos, Anthropic’s Powerful New Model

Federal agencies have requested access to Claude Mythos Preview, which Anthropic says can rapidly identify — and potentially create — new cyberthreats.

nytimes.com logo
Apr 17 • 7:51 AM EDT • Business • nytimes.com
The Download: Anthropic launches Claude Science, and California’s carbon manure math

Plus: The US has lifted restrictions on Anthropic’s Mythos and Fable models.

technologyreview.com logo
Jul 1 • 8:10 AM EDT • Science • technologyreview.com
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Claude Helped a Hacker Find a Way to Issue Tickets to Almost Every US Music Festival

A researcher found that using Anthropic’s Claude Opus 4.7, he could break into the website of Front Gate—used by every festival from Lollapalooza to Bonnaroo—and freely issue any ticket he chose.

wired.com logo
Jul 1 • 6:00 AM EDT • Technology • wired.com
Anthropic doubles a science benchmark score with Fable 5.1 while OpenAI says its Astra model crosses critical cyber threshold

Anthropic’s Fable 5.1 doubles a science benchmark score, while OpenAI says Astra reaches critical cyber capability and finds zero-day flaws.

rdworldonline.com logo
Sep 1 • 5:01 PM EDT • Science • rdworldonline.com
Novo Nordisk Taps Anthropic’s Claude Science To Speed Up Drug Discovery — Here’s Everything Investors Need To Know

Novo will use Anthropic’s Claude Science in R&D to tackle scientific and drug discovery challenges, aiming to develop new medicines faster.

finance.yahoo.com logo
Sep 16 • 9:05 AM EDT • Science • finance.yahoo.com
Did Anthropic’s A.I. Really Make a Scientific Discovery on Its Own?

An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.

nytimes.com logo
Sep 27 • 4:57 PM EDT • Science • nytimes.com
Anthropic’s Claude AI can respond with charts, diagrams, and other visuals now

Claude can now help you visualize topics as you chat.

theverge.com logo
Mar 12 • 12:00 PM EDT • Technology • theverge.com
What’s In Anthropic’s I.P.O. Filing

The artificial intelligence giant reportedly believes that it’s on track for a record-breaking stock market listing, according to a prospectus seen by Reuters.

nytimes.com logo
Sep 29 • 7:58 AM EDT • Business • nytimes.com
No science background? AI does the lab work

Financial analysts used Anthropic’s Claude to design protein minibinders that bound scorpion toxins in lab tests—showing AI can compress drug discovery...

seekingalpha.com logo
Oct 20 • 11:11 AM EDT • Science • seekingalpha.com
AI Advice From Anthropic’s Head Of U.S. Small Business

Anthropic’s Lina Ochman explains how small businesses can use Claude, AI workflows, data connectors and employee-like prompting to save time.

forbes.com logo
May 28 • 1:00 PM EDT • Business • forbes.com
Mozilla Used Anthropic’s Mythos to Find and Fix 151 Bugs in Firefox

The Firefox team doesn’t think emerging AI capabilities will upend cybersecurity long term, but they warn that software developers are likely in for a rocky transition.

wired.com logo
Apr 21 • 2:30 PM EDT • Technology • wired.com
Anthropic’s Jack Clark Sees AI Supercharging Science—and Governments Need to Prepare

Jack Clark outlines how AI-assisted scientific discovery could boost research and growth, with safeguards and human oversight.

kingy.ai logo
Oct 17 • 9:09 PM EDT • Science • kingy.ai
We tested Anthropic’s redesigned Claude Code desktop app and 'Routines' -- here's what enterprises should know

For the enterprise, the Desktop GUI is likely to become the standard for management and review, while the CLI remains the tool for execution.

venturebeat.com logo
Apr 15 • 2:40 PM EDT • Technology • venturebeat.com
Google thwarts suspected hacker attempt to use AI for large-scale exploitation

Google says it blocked hackers using AI to find a zero-day and bypass 2FA, amid Anthropic’s delayed Mythos launch.

seekingalpha.com logo
May 12 • 12:21 AM EDT • Technology • seekingalpha.com
Anthropic’s Pentagon Battle Matters to Every Business

The designation of the artificial-intelligence company as a supply-chain risk puts every business at the mercy of President Trump’s political priorities.

wsj.com logo
Mar 13 • 5:30 AM EDT • Business • wsj.com
Sundar Pichai: Google’s Frontier Imperative, Compute Scarcity Dilemmas, Future AI Products and Businesses

Alphabet CEO Sundar Pichai has little patience for doubts about Google’s willingness or capacity to compete at the frontier of AI. His company’s latest Gemini 4 Argon model — long-promised and recently delivered — beats OpenAI and Anthropic’s latest public models on coding, math, science, and knowledge-work benchmarks and has placed Google’s AI back among the world’s best. Amid chatter that Google was fine with good-enough lightweight ‘Flash’ models, Pichai pushed back hard against any suggestion that company is limiting its research ambitions. “We won’t do it any other way,” he told me in a Big Technology Podcast interview recorded this week at Google’s Mountain View headquarters. Pursuing cutting-edge research is costly for Google, requiring compute and chips that otherwise could be sold at a high markup by its cloud business. But Pichai said allocating resources to frontier AI development is “ground zero” for Google. “Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development,” Pichai told me. In our conversation, we discussed Argon (which Pichai says processed three times as many tokens as Gemini 3 in the 72 hours after launch), AI’s role in developing better models, the AI interface of the future, competition with OpenAI, Google’s partnerships with Anthropic and Apple, data centers in space, and the nature of his optimism. You can read the full conversation, lightly edited for length and clarity, below, or listen to it on Apple Podcasts, Spotify, YouTube, or your podcast app of choice. Alex Kantrowitz: Google is back at the frontier with Gemini 4 Argon, which beats OpenAI’s and Anthropic’s public models on benchmarks spanning coding, math, science, and knowledge work. The conventional wisdom was that Google had given up on the frontier to focus on fast, good-enough models for its products. That was wrong? Sundar Pichai: Very wrong. Look, we are so committed to being at the frontier. It’s in our DNA. We won’t do it any other way. We’ve been thinking about the AI frontier for well over a decade now. The frontier is very dynamic. It’s very competitive. It’s very exciting. I couldn’t be more pleased with how Argon has come together. We took our time with it. We made sure we tested it safely and deployed it carefully. We took a bit longer than our other models, given its capabilities. Across the board, be it for agentic work, knowledge work, coding, creative tasks, Argon is one of the really good frontier models. The first 72 hours since we launched, it’s almost up to 25 trillion tokens used, which is about three times what Gemini 3.0 had in the first 72 hours. And we are capacity constrained as we are serving it. Excited, but there are always areas….. You know, the frontier is very dynamic, and you have to keep evolving the models. There are areas which we can see we need to improve as well. We’ll be at work on all of that as well. Which areas? On any given model, Argon would be across the board better at everything if you just look even two months back. But the space is so evolving. Even on coding, for example, there are pockets where we know we need to do better, and there’s clear feedback. We’ll make it better. The argument for standard models is that they’re already good enough to build great products, with the frontier valuable only for certain tasks. Meta built Muse with good models rather than the best, and Google could put standard models into Maps, Gmail, and Search. Why isn’t that sufficient? It’s definitely not how I have thought about it at all. We are deeply committed to driving the state of the art and actually pushing where this technology can go, all the way from transformers. That’s a journey we’ve been on. You will see us continue to do that. When you’re at the frontier, you get an earlier look into the emerging capabilities, earlier than others, which helps you better prepare for the future. We are fortunate to have a wide set of opportunities across consumer and enterprise. Some of our cloud customers, for sure, want the model at the frontier. The frontier models will be better at developing the next set of models in an era of recursive self-improvement. I would argue it matters there. Internally, we have definitely seen a steep point of inflection by deploying Argon to our developers. It definitely tackles problems which our previous models could not do. Being at the frontier puts you at the innovation frontier and helps you drive that as well. There is room for models of all sizes and capabilities. That’s why we did Flash, Flash-Lite, etc. I agree with you that you can develop very good product experiences with not necessarily the most frontier model, because they tend to be slower and more expensive too. But we care about the Pareto frontier, and we’re committed to doing all of that. You said developing frontier models gives you a look at what’s coming. What do you see on the horizon? What makes this moment so exciting is you build something which you think is a culmination of months of work, and you put it out. You already see clear headroom ahead. We’ve all been working on these agentic, long-horizon capabilities, but clearly the frontier is going to have multiple of these agents working together to do things. That’s an example of an exciting paradigm underway. It’s also clear to me that users, both in consumer and enterprise, will have access to some multi-agent framework for them, working all the time doing things. It feels like a moment of infinite possibilities. Sergey Brin said one of Argon’s core innovations was relying more on the model to help develop the model. Yet incidents involving OpenAI’s bots breaking containment and Google’s bots accessing a site they shouldn’t have suggest these systems still aren’t perfectly aligned. Isn’t there reasonable cause for concern about accelerating toward recursive self-improvement? There are three parts to your question. Let’s first talk about RSI itself. You’re right, Sergey mentioned RSI being a critical contributor as we are developing Argon. But to be very clear, today, in a continuum, we are pretty far from the end state of RSI or something like that. The right way to describe it is you have RSI loops along with AI researchers in various aspects of model development. You almost have agents helping AI researchers in some automated way work together to build these models. It’s good to at least understand where we are today, and it’s super exciting. I expect that continuum to keep making progress as we go into next year. The second question is around safety. Security comes from defense in depth. You’re talking about alignment, obviously. We all are doing a lot of work to make sure the models are as aligned as possible. But it’s an active area of research, and there are clear gaps. That’s not the only thing we rely on. You have the work you do on alignment, but beyond that, we put a lot of effort into real-time monitoring as these models are working. Making sure you have good telemetry into what’s happening so that you can intervene in real time if you see unexpected behaviors. How you do that, the architecture with which you do that, how you make sure it’s all sandboxed and isolated in a way that it can continue doing its job during real-time monitoring — these are all areas of investment. Obviously, when we deploy these models, giving customers, enterprises, control, both with real-time monitoring, but their ability to decide where they deploy, what type of data which models ever have access to, etc. All that work is very, very important, and we are doing a lot of that. As an industry, we need to constantly up our game and take the time to do all this stuff, including dedicating the compute required to make sure you can safely deploy these models. The third part is: Is it all enough? This is why there are a lot of conversations in the industry, and I think it’s reasonable to be worried. The right way to approach something you worry about is early on thinking about what more we can do. As an industry, you’re definitely seeing increased levels of work on alignment, testing for safety, etc., as we deploy these models. The next step would be developing better standards so there are cross-industry standards of how we do these things, including the ability to evaluate using independent evaluators. If you look at areas like financial controls, we have accounting standards, we have independent auditors. Those are all the next natural steps for us as an industry to work toward, and regulation will end up playing a role as we go through all of that as well. Google pursues both language models and world models, while some other AI companies like OpenAI have focused more heavily on LLMs as the path to AGI. Why is world-model research important to you? As humans, you obviously perceive the world around you, and you’re taking all those inputs. Making sure these models are able to understand the laws of physics, simulate the world in high fidelity. All that, I think, are key enabling blocks for intelligence. We are working across all possible applications of this. Take an area like robotics. It’s not an accident: If you look at embodied reasoning benchmarks, Argon is state of the art. That all comes from our experience building world models. Inherently, I would expect there will be architectures which will converge all of this in the future. But for us, we view this as, today, this jagged frontier that is intelligence. We want to be at the frontier of all the possible approaches, and that will help us both drive better research, better insights, and develop a much better AGI model, is how we think about it. Some people argue Google should focus on selling its computing resources rather than using them for AI research. Cloud wants to sell compute at a high markup, while researchers need a very big computer to build the best models. How do you balance those demands? Ground zero for us is making sure we are investing in the compute that’s needed to be at the AI frontier. In 2015, I set the company to be AI-first. AI is that key horizontal ingredient across everything we do, all the way from Search to Cloud to Waymo. That is ground zero for us, making sure both for research and developing the models that we have enough compute needed. Beyond that, we have these independent businesses which each have their own long-range plans. They’re using those long-range plans to project forward, and we plan for compute for all of them. The cloud team, they have a business and they have a projection and they have demand signals. They have committed contracts. With that help, we can plan on a long-term compute trajectory for them. We’re fortunate to have this wide set of opportunities. There’s no company in the world which isn’t making trade-offs at any given moment in time. But the first principles we operate on is making sure we have enough compute to invest in the frontier, and that’s non-negotiable, and everything else works on top. Remember, we are building our own compute, our own data centers. There are long lead times. The compute we have today is a function of decisions I made in 2024. Even if you think back to a year from today, last year the agentic coding takeoff hadn’t happened. Today, obviously, when you sit and look at anything, everyone is short—not just us, other companies—and everyone wishes you had two times what you had planned for. That comes with the territory. At any given moment in time, we are planning for what we would need two to three years out in the future. You’re going to find some decisions you make may look suboptimal two years out, depending on where the state of the art is. I don’t spend too much time thinking about it. The way I think about compute allocation is making sure Google DeepMind, both for research and frontier model development, is cutting edge in terms of compute access. After that, we plan for all our businesses. It’s great we can provide our compute to other people too, like we have done. It allows us to scale that up, get real tests for it in the widest application set possible, test it in the real world, and make sure we are at the cutting edge of technology at every layer of our AI stack as well. Ben Horowitz relayed on a podcast that Andy Jassy had said compute was sold out until 2028. Are you seeing the same thing? If today a customer is coming out and asking us for compute in ’27, that is incredibly difficult to do. Even last year we went out and leased some short-term compute to accommodate some customers and help them out. But yes, we are all dealing with similar timelines. Every major technology shift seems to involve overbuilding, from railroads to fiber. Do you think that’s happening here? It depends on the time frames you’re looking at. This level of build, if I take a long enough time frame, it makes complete sense to me. We are at early stages of the most consequential technology ever, and this is not like fiber. It’s not dark. We are using it. We are capacity constrained on a daily basis. The applications, the underlying technology is improving rapidly. But running a company, the way I work through the moment is you look at your demand signals. You look at your committed revenue opportunities that you’re getting in the form of contracts. You balance that with the underlying technical capability, or internally you balance how we are using it internally, the model trajectories. Based on all that, you take a disciplined approach—a confident, aggressive, but disciplined approach—to plan out compute. But when you talk about the broader economy as a whole, you’re having people operate with various levels of risk. I focus on what I can control as a company and plan through it. If your question is, can there be an overbuild? Yes, because you can have some constrained components. Remember, what matters is a set of everything you need to build out that compute. Memory, electricity, electricians…. Land. Like 2,000 components or more. You could get constrained at some point. There could be things which cause bottlenecks, and then you could have overbuilds. There could be external shocks to the economy. There are macro risks. All that is possible at any given time. But am I confident that the compute we are planning for, we will have uses for it given enough time? Absolutely, yes. I was in the room when you said AI would be as profound as fire and electricity. If you believe that, shouldn’t you give researchers the biggest possible computer, even at the expense of today’s cloud profits? We’re all doing some form of that. Our cloud business is at any given moment in time forgoing short-term revenues because we are making compute trade-offs to support frontier AI development. What you’re seeing is true already. But you want to be thoughtful. Even our AI researchers have some constraints, which are also good. That’s what inspires creativity. That’s what helps you come up with a more efficient algorithmic breakthrough, maybe to use less memory. What we are committed to is to invest what’s needed to stay at the frontier. OpenAI President Greg Brockman told me a few months ago that the ideal AI product might have no interface at all—just as natural as conversation. What do you think the interface looks like in the age of AI? Computing historically has been humans adapting to computing. With AI, it’ll be the other way around. The technology will adapt seamlessly to how humans live and go about their day-to-day life. You want to be able to speak to that AI when you want to. It has context. It can be persistently running somewhere, give you continuity. You’re not dealing with a lot of complexity. It’s natural. All that makes sense to me. That doesn’t mean it won’t have any interface, however. Nowadays, even on my phone, Gemini voice models are so good. I can just press the microphone button. I can just ramble. That’s why we call it Rambler. I can ramble. It intelligently corrects with my personal context. Even my friends’ names, weird names, it gets it right, even if it first guesses it wrong. It’s amazing. I’m not going in, backspacing, editing once I finish saying it. It’s remarkable how good it’s gotten. But there are going to be moments you will need an interface. You may want to entertain yourself. You may want to watch a video. You may ask your AI to create something, and you want to watch it, consume it. The way I think about it is, you want it to be as seamless and as natural as possible, and that you are not doing the hard work adapting to whatever the interface is. The technology is adapting to how you’re working at any given moment in time. When I asked Sam Altman about competition from Google, he argued that OpenAI was building AI-native products and implied Google was bolting AI onto existing ones. Do you accept that framing, and can a “bolt-on” compete with an AI-native product? First of all, it’s a very dynamic moment. We are all pushing each other. OpenAI has pushed us as a company too. This is not just we are doing something to them. Far from it. Yes, Google went into its own version of a code red too. In the AI moment, all of us have to respond with varying levels of urgency at any given moment in time. We are constantly building new products as well. Gemini was built from the ground up as a product—the Gemini app I’m talking about. Or tomorrow, as all of us are adapting to agents, are you bolting agents onto ChatGPT, or are they building it natively? How would you think about that? You can always put these questions back. I don’t think of it that way. I think of it as you want to build world-class product experiences that are AI-native and they are winning. Some of it is adapting products, some of it is rethinking new experiences. They will all be part of how you approach this moment. How do you expect to make money from these AI interfaces? If an agent recommends a product and I buy it, should it take a cut of the sale, even if that’s disclosed? I’m going to put enterprise aside. Consumers are going to increasingly value this technology. Take software developers today. Developers are willing to pay for these coding models because it really helps make them more productive. Nobody would want to code the way they were coding three years ago, or even the same time last year. When you’re delivering value, there’s value to be had. I’ve never seen examples where consumer products really scale to billions of users, where people are using it intensely, and haven’t had monetization to go along with it. If you’re providing value to people, there is inherent value to be had. The nature of it may change. You’re asking a scenario in which agents are doing stuff for you. At the end of the day, you will have commercial needs. The agents need to fulfill those commercial needs. The providers on the other side are going to see value in that. There’s going to be some mechanism by which it gets fleshed out. That’s what an efficient system does. But what matters is that you’re building those world-class consumer experiences. I promised myself one product feature request: Can you make Gemini-powered search in Gmail as good as searching Gmail through ChatGPT? What’s going on here? One of the exciting things we announced recently is the unified Gemini agent for enterprise, and we’re bringing that to consumers. These are persistent agents which run 24/7 in the cloud. We’re spinning up a micro VM effectively for every query, and from the runtime, the harness, the model—it’s all a headless service. It’ll work everywhere, and it has your context with you. You can address this agent whether you’re in Workspace, in Search, in Gemini. Agents are going to drive this unification from a customer experience, which people are looking for. When you have a broad product portfolio and you’re moving forward fast, there are always areas where you’re moving forward faster than some other areas. That’s valid feedback. But we are putting a lot of time and effort into making sure, as we build out our agentic experience, that unification and that capability works well across all these services. People have asked where Google’s equivalent of Muse or Dots is. Do you anticipate creating a new product to compete with them? Our goal with Gemini is to be a personal, proactive, and powerful assistant. That’s what we are working toward. You saw us describe the early versions of it at Google I/O this year with Spark. Effectively, already, if you open the Gemini app as a Pro or an Ultra user, you see Chat and Task, and they start giving you that agentic experience. With Argon now, that capability is dramatically accelerated. What we announced recently in our enterprise event, we are bringing that to consumers as well. Soon in Gemini, you will be able to ask something, and it’s a continuum. You don’t need to think about whether you’re asking a chat or an agentic task. It’ll just automatically do the right thing, and it can work persistently in the background securely and get things done for you. Already, empirically, when I look at what’s coming into Gemini in our app, last year you would have tagged them and most of them would have been chats. But a steadily growing percentage is already agentic tasks in Gemini. Yes, we are going to bring personal agents to our consumers. It’ll work in the Gemini app. It’ll work in Google Search. It’ll work in Gmail. You can address it, call it, etc. We want to make sure we’re getting it right. It’ll be powered by Argon, and we are very excited to bring it to our users. Google has invested and committed tens of billions of dollars to Anthropic. What do you see in Dario Amodei that makes you want such a deep investment and partnership? Very early on, when we looked at the founding team of Anthropic, it was very clear to us this was a world-class team which was involved in some of the earliest GPT models. We were quickly able to assess that they would be at the frontier. We’ve always tried to identify and partner with companies which would be at the cutting edge of technology. We’ve done that with SpaceX. We’ve done that with Anthropic. That’s what we saw, and we had a chance to partner. Is your partnership with Apple to license Gemini for Siri expanding, contracting, or standing still? For both us and Apple, that partnership was about translating the capabilities of AI into better experiences for users. I thought Apple has done a phenomenal job of incorporating—they customize these models and build it into Siri—and it’s been great to see the reception. We are committed to doing more. You’re going to do more with them? There’s nothing specific to comment, but it’s a partnership. It’s working well. What have you learned so far about the feasibility of data centers in space? It’s a very exciting project. Projects like this remind me—I still recall that moment in the desert for the DARPA Grand Challenge, watching the Stanley car compete in it, which ended up being the basis for Waymo. With all these technologies, you’re at a moment in time where it looks a bit like sci-fi, but 10 to 20 years down the line, it’s actually working in a meaningful way. I feel the same in space. We’ve always believed in betting big on these technologies. Quantum has been a great example of it. We’re probably 10 years into the journey. Waymo, we are almost 20 years into the journey. Space, we are two to three years into the journey. It’s clear to me that it’s an approach which will make a lot of sense in the future. Being in sub-synchronous orbits with 24/7 access to the most abundant form of energy we have access to will make a lot of sense for this exponential increase in compute that we are going to need. Having said that, this is a challenging project. The team has disciplined milestones. It was a super exciting milestone to send the TPUs up to space. Sometime, as we are speaking, we are expecting a “hello world” moment from them. I look forward to seeing that happen, and we’ll continue investing here too. You previously said 25% of the code written within Google was written by AI. What’s the number today? That number in our world today is meaningless in the sense that every part of what we now touch is influenced by AI deeply. What we are tracking with Argon, for example, it’s been a point of inflection. People are using Argon to really go tackle complex projects, including projects which affect millions of lines of code. In the four weeks since we have launched Argon, we have seen a 30% increase in CLs, and more importantly, almost a similar increase—a one-third decrease in rollbacks. People are writing code more productively and better code with it. We are tracking it with newer metrics now. How are you dealing with opposition to data centers? If you can’t build in the U.S. the way you want to, where else do you go? We’re very committed to building our data centers very responsibly. When I look at our largest data centers in some of the communities where we have been the longest, I visit them, I talk to people. There are people who come and tell us their kids have gone to college because of our investments in these communities, and we’ve grown in those communities. To me, this is about doing it right. Engaging with the communities early, doing it transparently. We are committed to making sure we are bringing incremental power, and we cover 100% of the cost of our power needs for these projects. It’s understanding the impact on neighborhoods and making sure you’re working thoroughly to address them. Done rightly, you can continue making progress. But we are constantly taking feedback into account. I do worry not everyone operates the same way. People have been surprised by data centers showing up in their backyard. Those are all important. As an industry, we should continue to do better. But part of the reason, in a 20-year time frame, we are thinking about things like data centers in space is making sure we are able to put these data centers where maybe the trade-offs will be different. What unproven area of AI is Google working hardest to crack? Is it continual learning—getting models to keep updating after release—or something else? There are multiple parallel paths. You saw with Argon we have a million output tokens. With our Gemini models early on, we had a one-million context window on the input side. These are all examples of breakthroughs we are constantly working on. How do you think about synthetic data? How do you think about continual learning? How do you think about more efficient architectures? We do dedicate a meaningful percentage of our compute to these research bets too. It always goes hand in hand, including our world models. Those are all bets we are placing. Sometimes, as part of these bets, there are ideas that emerge which just make their way into the mainline models. Maybe we don’t fully talk about it, but we have multiple steps in these areas. Working in technology requires optimism that building something will improve the world, but those bets can leave real consequences when they fail. I recently returned to a town in El Salvador where enthusiasm for Bitcoin had given way to unfinished construction and something resembling a ghost town. How do you maintain the optimism you spoke about in your Stanford commencement address while accounting for those risks? I genuinely have a deep conviction that improving technology and improving access to technology makes people’s lives better. It’s been my personal experience in my life, out of which comes that deep conviction, optimism. But with that, I’ve always felt humanity’s journey is always about working hard to harness that technology to make it work well for society. The optimism is not an optimism that you just build whatever you want, whenever. You work hard to make sure you’re building technology in the service of humanity, to make the human condition better. That’s got to be the defining goal as we are approaching it. With that framework, I’m very, very optimistic. We are in very early stages of the kind of progress that we are going to see on many areas. We’re all talking about areas like healthcare. A lot of the progress is ahead. The ability to make things in a fundamentally cheaper way on many things where things have been getting expensive for a long, long time, discovering new materials, etc., which really bend the curve—it’s tough to step today and understand the impact of all that, but they’re going to be very profound. I’m very optimistic, but we have to be rightfully concerned about all the ways this technology can go wrong. Sundar, I know you don’t do many of these. Thank you. Thanks, Alex. Appreciate it.

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Oct 20 • 1:47 PM EDT • Technology • bigtechnology.com
August Monthly Review: ChatGPT In Epic

Death, taxes, another frontier lab healthcare launch inspiring truly insane LinkedIn takes. As much as I want to stay away, I repeatedly am the crewman unplugging his ears whenever we pass these sirens. So it’s not the first and probably not the last time we dial up the typewriter rather than tie ourselves to the mast. The full blow-by-blow timeline: Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe The End of the Standalone PHR (Jan 8): ChatGPT Health arrives for consumers, at the time powered by b.well. I was bullish on the approach in that the best way for the PHR to finally solve distribution was to meet consumers were they already are (i.e. When Horizontal Meets Healthcare (Jan 9): OpenAI for Healthcare puts out the shingle for enterprises, with SharePoint ingestion standing in for the EHR integration the product actually needed. Another One: Anthropic’s Healthcare Debut (Jan 16): Claude's version, on HealthEx rails instead of b.well, with Agent Skills for FHIR development as the one true vertical-specific investment. ChatGPT for Clinicians: The Trap Sprung (Apr 24): OpenAI filled in the missing GTM middle with a free product for verified clinicians, effectively peeling the enterprise wrapper off ChatGPT for Healthcare and taking the PLG fight directly to OpenEvidence. OpenAI’s Second Attempt at Health (Jul 31): a relaunch of their patient specific app, now branded Health in ChatGPT, where the privacy partition came out, the connectors thinned, and b.well disappeared in favor of first-party FHIR work against a smaller network Beyond a Shingle So what was announced now? Today, we’re introducing a new electronic health record integration that brings authorized patient context from Epic into ChatGPT for Healthcare, along with the Healthcare Public Data plugin for direct, structured access to official healthcare datasets like PubMed, DailyMed, and CMS Coverage. Together, these capabilities bring ChatGPT closer to the systems and sources healthcare teams trust, while supporting the controls and compliance healthcare work requires. The core portfolio is unchanged from prior announcements we delineated and discussed (aside from the relaunch of patient-facing). Since trade publications still seem to be confusing them by using the wrong names: Enterprise sales motion: ChatGPT for Healthcare Protecting their core product / PLG: ChatGPT for Clinicians Consumer/patient-facing product: Health in ChatGPT So really, this is a feature release (specifically for ChatGPT for Healthcare when it comes to EHR integration). What’s cool about it, though, is that we are moving beyond just putting out a shingle. Everything in the January enterprise launch was horizontalizable: Horizontal tech companies thus generally start verticalization with their “putting out a shingle phase”. Telling the world you’re open for business as a horizontal tech company reliably attracts early inbound interest from buyers who are already trying to force-fit horizontal tools into domain-specific workflows and are eager for any signal that the vendor intends to support their use case more directly. Nothing was really vertical specific, which is exactly what you'd expect from the ultimate hypergrowth horizontal company dipping their toes into specific industries. But eventually you have to stop changing the sign on the door and start changing the product. Can you guess where the horizontal product was going to run out of road? This is the core dilemma writ large: verticalization requires differentiation, while scale economics of consumer and horizontal push toward unification. I’ve buried the lede so deep here it will be painful to some readers, but what should be shocking to no one is that my perspective is that EHR integration is the only path that meaningfully resolves this tension for ChatGPT for Healthcare. Integration with Microsoft Sharepoint is fine, but it is categorically insufficient for any product that hopes to influence clinical decision-making. SMART Money Well here we are, eight months later! Real vertical investment has begun, which surprised a few people. One friend in the industry messaged me: “Absolutely no way Epic gave ChatGPT API access.” Looking forensically at the announcements, the integration is notably read-only across appointment notes, laboratory results, medications, and specialist documentation. So while I’m not a betting man, I'd wager the house this is a SMART on FHIR launch: That sounds a lot like USCDI! The recommended path for the workflow they outline would be SMART on FHIR Their Health AI lead’s post is evocative of both standalone and EHR launch SMART, which another termed “ChartGPT” and “EHR Plugin” The implementation burden for SMART on FHIR is the lowest of the available integrative paths This is the team who literally did patient-facing SMART on FHIR with Epic last month Most importantly, if you’re a horizontal company, you generally still haven’t taken the full plunge and thus (overly) value reusability. SMART on FHIR is the logical compromise: healthcare-specific enough to matter, but standardized enough to reuse. Nobody Asked Judy Another friend asked “I thought they had to go to each health system, or did they go direct to Epic and now health systems opt in?” Given the trust paradigms in healthcare, this functionally cannot be Epic hoovering up all the data for OpenAI and shoving ChatGPT in their customers’ faces (or they would revolt). However, I do believe the aforementioned terrible coverage by TechCrunch and other outlets is probably responsible for that question, given the 325 million reference. When using FHIR as a business associate to an Epic customer, there is no EHR gatekeeping to speak of, as that isn’t how fhir.epic.com works: You register an app You pick your APIs You test against the sandbox APIs You list as “Ready for Production” Hospitals pick your app You test and go live with them Bluntly, nobody had to say yes or no in Verona (nor were they given the chance). Vendor Services (their next developer tier up that I doubt OpenAI is using quite yet in this initial release) certainly has contractual paperwork that some resent, but even there, the twin pressures of mounting antitrust and information blocking make outright gatekeeping increasingly fraught. My friend’s sentiment is, to me, representative of a broader industry neurosis, perhaps a sort of scar tissue of prior eras: people assume the gate is still there and never actually try the door. There are certainly other ways Epic (and any EHR) can put its thumb on the scale, but they are not so dumb as to stand in front of a federally mandated API and play bouncer at this exact moment in time. So I think they can and probably should go deeper, as this release is at best parity and at worst behind vertical-specific competition. OpenEvidence did a basic SMART launch with Sutter Health in February, allowing for more convenient evidence search by providers. They then add patient-context (the equivalent SMART on FHIR flow to what we see here) when Cedars-Sinai went enterprise-wide in May. UpToDate has four distinct applications across deeper workflows like patient engagement listed in Epic Showroom and announced a partnership with Epic to power Art at UGM Abridge and other ambient scribes have invested deeply into the deepest bidirectional clinical copilot workflow with integrations well beyond SMART on FHIR. In that light, the “Who is OpenAI primarily targeting here?” is clear. This release brings them into striking distance of OpenEvidence, but not the others quite yet. They are the only one of the three you can reach without building something truly Epic-specific. When will they go further? Competition is a great motivator to overcome the horizontal demons and start building things that can’t be reused: not across industries, not across EHRs, maybe not past the customer you built them for. That’s the price of actually verticalizing. The question is if and when OpenAI will be willing to pay it. Month in Review Here is the monthly review. As a reminder, this is a regular round-up of the month’s posts and other content to surface things you may have missed across regulation, litigation, interoperability, and beyond. AI assistance is used in these bullet summaries so I can focus on articles. Articles Published: None this month Video Content: The Information Exchange: Standards-based Thruple Edition (Aug 14): Back to school for us too, with Brad reporting in from the CMS Health Tech Ecosystem’s one year anniversary in DC. We get into the January CMS-0057 deadline, the fall rulemaking reading list, and why enrollment still keeps most apps off FHIR. The Information Exchange: Epic Dúnadan Edition (Aug 25): A UGM roundup with Ryan Brickner joining for the first time to check our takes against what the building actually thinks. Rangers, Ergo sitting on top of EHI, and a down-market lineup that needs some cuts. Regulatory: Stacked Deck, Bad Hand (Aug 05): ONC’s website refresh took the entire HIT Policy Committee record with it, so I rebuilt the archive and went looking for the regulatory capture story everyone assumes is buried in there. Stacking the deck and winning the hand turn out to be very different things. The Sixth Generation of Patient Access (Aug 19): A quick catalog of the five generations of patient access we’ve layered on since HIPAA, and the two candidates now competing to be the sixth. One is planned. The other is the market routing around the plan entirely. Court cases: Three Cases Walk Into a Docket (Aug 06): Two surprise settlements cleared the board in a single week, and then Judge Maddox dropped ninety-four pages on Vyne v. Henry Schein. The sleeper is a DMCA holding that makes direct-to-database a considerably riskier business model. Epic v. Health Gorilla: Into the MDL (Aug 10): Nine class actions are headed to Miami, and the Panel signaled it wants to bring the case that spawned them along too. That would leave Epic arguing the requests were obviously fraudulent in one courtroom and unknowable in the other. Amazon v. Perplexity: Agents Are Legalized! (Aug 11): The Ninth Circuit vacated the injunction against Comet, holding that the user is the one accessing the servers rather than the company that built the agent. A real win for agentic access, and a much narrower one than the headline suggests. Veeva v. Epic: Come At Me, Bro (Aug 26): Epic’s response brief wants the dismissal affirmed and, unusually, wants the opinion published as precedent. Buried in it is Epic’s own description of what its non-competes actually prohibit, which current and former employees should read closely. EHRs: The Contract Epic Would Never Sign Today (Aug 04): A 1999 SEC exhibit catches Epic licensing nearly its entire product line, Tapestry included, to the company that became TriZetto. The marketing services menu attached to it is the part that will make you blink. Forecast from Verona (Aug 07): The Epic Almanac makes one argument six different ways: the AI is only as good as the networks behind it. Emmie headlines, Art’s context stack is the most ambitious part, and Penny finally gets an autonomous coding date on the calendar. Works With Epic MyChart (Aug 17): Epic’s first new Showroom category since the death of Workshop certifies hardware instead of software, badge on the box and all. Made for iPhone, but for blood pressure cuffs, and rough news for anyone selling the RPM stack sitting in between. UGM Hot Takes 2026 (Aug 20): Everyone else covered the AI announcements, so I went after Savvy deleting the payment gateway, Rangers as Boost with the timer removed, and a down-market lineup with too many entries. Plus the Health Grid tidbits I cannot help myself on. MyChart Central Grows Up (Aug 24): Device data and Emmie turn Epic’s identity hub into a full consumer platform, which is both a logical answer to ChatGPT and a bit of a mistake. It also happens to be the best scraping target Epic has ever shipped. Industry Analysis: The Wrong Yardstick (Aug 12): Vertical software keeps getting judged against Superhuman and Notion, which is the wrong bar entirely. Your user is comparing your product to a whiteboard and forty phone calls before lunch. Primitives vs. Abstractions (Aug 27): Developers want building blocks, systems of record prefer to hand out business logic, and both sides have a real case. There’s no test from the outside that separates the engineering reason from the competitive one, which is why this keeps ending up in court. Cross-industry Comparisons: The Two Kinds of Platform Power (Aug 18): Attention power and record power are different problems that keep getting handed the same regulatory toolkit. Congress’s latest swing at Big Tech shows both what’s possible and where it falls apart. The Dogs of (Platform) War (Aug 21): A CourtListener alert turned up a property management fight with healthcare’s exact shape and none of the Cures Act. Shell prospects, ghost accounts, a notetaker bot that came back to haunt someone, and a lawyer arguing both sides of the same theory in two states. Fractals All the Way Down (Aug 31): Yardi dominates property management right up until you zoom into one segment, where AppFolio owns it outright and Yardi doesn’t appear at all. Where you draw the line around a B2B software market is about to decide an awful lot of cases. Other News: If Judy Had the Courage (Aug 13): A short eulogy for the era when software was allowed to look insane: WinAMP, bold colors, and everything the grey chatbot era has taken from us. External Media: Portland Monthly Health Tech Meetup: Erin O’Brien channeled my own feelings - maybe it’s just because it’s August and beautiful, but the monthly edition of the PDX Health community meetup was a ripper. Make sure to reach out if interested to join for the next one. STAT’s Coverage of Epic This Month: Brittany Trang of STAT did a fantastic job of breaking the FTC investigation that’s been lurking, as well as UGM related coverage, so I had to give her her wish of a meme. Fall Conferences: I’m pumped to be kicking off my fall conference season in NYC at Nabla Accelerate next month, which Chrissy provided the link to apply for. Here’s the rest of my schedule in case you want to meet up: Commonwell (Redwood Shores, CA): Oct 13-14 Open@Epic (Madison, WI): Oct 21-22 eHealthExchange (Austin, TX): Oct 27 Sequoia Project (Austin, TX): Oct 28-29 HLTH (Vegas): Nov 15-18 RSNA (Chicago): Nov 29-Dec 3 Posts I Liked: HTI-6 Should Unbundle API Certification: Josh Mandel makes the case that HTI-6 should split (g)(10) into separate authorization and data certifications, so a PACS or a genomics platform can certify only the role it actually performs. Imaging is the urgent example, but the structure solves a much bigger problem. On implementing ePrior Auth with Epic: Scott Rossignol’s field notes from a live ePrior Auth build on Epic, including the two app registrations nobody warns you about and the CPT mapping problem waiting at the end. CMS-0057 implementations are going to be such a beast. Healthcare point solutions are starting to look a lot like streaming services: Spencer Dorn runs the cable-to-streaming arc against health IT and lands squarely on the bundling half of the cycle. Bundling can be good! It can also be bad! Life is nuanced. Health API Guy is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. Subscribe

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Sep 2 • 5:05 AM EDT • Health • healthapiguy.substack.com
Did AI find a new gene-editing tool? Why Anthropic’s ‘autonomous discovery’ is sparking controversy

Anthropic’s claim its AI agents discovered an unusual pattern in viral DNA similar to what’s seen in the gene-editing tool CRISPR Cas-9 has set off a wave of skepticism and controversy. Here’s what to know.

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Oct 8 • 9:58 AM EDT • Science • cnn.com
Claude Science is Anthropic’s newest flagship product

The company is doubling down on AI for science.

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Jun 30 • 5:50 PM EDT • Science • technologyreview.com
Deep dive
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Claude Mythos AI Model Uncovers 271 Zero-Day Vulnerabilities in Firefox

Anthropic’s latest frontier AI model, Claude Mythos Preview, has identified a staggering 271 zero-day vulnerabilities in Mozilla Firefox marking a seismic shift in AI-powered cybersecurity defense. The findings, addressed in Firefox 150, represent the most significant single batch of security fixes in the browser’s history. The discovery didn’t happen in isolation. Since February 2026, Mozilla’s […]

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Apr 22 • 1:01 PM EDT • Technology • cybersecuritynews.com
Trump Administration Reignites Its Feud With Anthropic Over Latest A.I. Models

The administration’s surprise restrictions Friday cut off foreign access to Anthropic’s latest models and sparked another round of finger pointing.

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Jun 13 • 8:41 PM EDT • Politics • nytimes.com
‘He has to find a way to be friends’: The political fight behind Anthropic’s export controls

In an administration that rewards political deference, Anthropic’s CEO has repeatedly clashed with the White House.

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Jun 19 • 12:00 PM EDT • Politics • politico.com
Anthropic's new "J-lens" reveals a silent workspace inside Claude that mirrors a leading theory of consciousness

Anthropic’s new Claude research reveals a hidden internal “global workspace” that resembles human conscious processing, raising major questions about AI reasoning, interpretability, safety, and machine consciousness.

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Jul 6 • 5:00 PM EDT • Technology • venturebeat.com
AI needs science’s search history

“Actually, that’s where the gold is,” said Alasdair Russell, my graduate school friend who leads a pre-clinical genome editing group at Cambridge. He was talking about the winding road of science that is omitted from published papers. “When you’re discussing how to do the experiment, and why this way is better than another way, and what does the data really mean? I know what it shows, but what does it mean?” At RAAIS 2026, he described how his group has begun logging the twisting path of discovery as it happens, recording the verbal and written exchanges that normally disappear. Ideas become nodes in a living graph: they branch when a meeting produces two plausible experiments, merge when separate lines of evidence converge, and go dark when someone quietly stops pursuing them. In his implementation, one agent scores novelty, while another tries to learn “how scientists think and how they navigate through a complex world of data,” so that high-potential nodes can trigger deeper investigation. As frontier AI labs deploy agents toward scientific discovery, giving AI authentic scientific taste remains a trillion-dollar dilemma. The bottleneck is that the record we have kept for centuries of science might be insufficient to get us there. The experiments that never make the paper Peter Medawar, 1960 Nobel laureate and “father of transplantation,” asked in 1963 whether the scientific paper was a fraud, and answered yes: the form of the paper misrepresents the thinking that produced it. Sixty years on, the diagnosis is unchanged. A paper presents a clean progression from hypothesis to result to conclusion. Lost along the way are the unconventional theories, the abandoned or unaffordable methods, and the underwhelming and inconclusive data. It reads like a browser history with every dead end deleted: the ten open tabs, the four rephrased queries, the wrong turn down a subforum. All scrubbed, leaving one clean path from question to answer as the canonical path. What has changed since then is that the discarded material is now worth something. No high-impact journal wants these artifacts, but raw trial and error is the most likely source of the training data required to develop scientific intuition, or what researchers call taste. Earlier attempts to capture the discards were motivated by scientific integrity. The Journal of Negative Results in Biomedicine launched in 2002 to publish rigorous studies that disputed established models or exposed ineffective treatments. Its archive preserved negative conclusions after they had become papers, rather than the live alternatives and arguments that produced them. BioMed Central closed it in 2017, saying the mission had been served now that other journals publish null results. A less generous reading is that in fifteen years it published around 200 papers because almost nobody wants to read a negative result, let alone write one up when it will not count toward academic tenure. AI models are different. Even an uninteresting negative result can be useful, provided it is labeled. Earlier this year, Anthropic put a version of this to the test. The company pulled 129 decision points from real Claude Code sessions between January and March 2026, showed models the work up to a human detour, and asked what should happen next. Claude Mythos Preview beat the human choice 64% of the time, while Opus 4.5 managed 51%. The comparison was tilted toward the models because Anthropic deliberately chose moments where the human decision had room for improvement. On 127 further scenarios where the human action was already strong, the models improved on it only about 20% of the time. The study was possible because Anthropic’s researchers work inside a tool that logs by default. The reasoning, detours and outcome are produced in the same working environment. Biology has no equivalent. Its reasoning happens in hallways, at benches, in Slack threads and on whiteboards, while the outcome arrives weeks later somewhere else. The record has to emerge from the work itself. Ask scientists to reconstruct it afterwards and we’ll create another polished account. Subscribe A log is not a label Before any of this becomes training data, a negative result has to say what failed. The first paper published in the Journal of Negative Results in Biomedicine examined 234 negative studies across five leading medical journals. Only 30% discussed statistical power, and half clearly defined a primary outcome. Tell a model an experiment failed, without telling it whether the assay was underpowered, a reagent had degraded, or the hypothesis was simply wrong, and it will learn noise with confidence. Decision histories have a second missing label too. When a lab considers five experiments and runs one, only the chosen branch returns an outcome. The other four are experimental counterfactuals. Researchers call this the selective labels problem: the data reveal results only for the actions someone chose to take. Such a record can teach a model to imitate a lab’s taste, but it cannot establish that the taste was good. It also smuggles local constraints into general lessons. A lab that never ran cryo-EM because it did not own a microscope teaches a model that cryo-EM is rarely the right call. Alasdair’s nodes preserve the candidate set, which is the necessary first step. To be useful, each decision record needs six fields: The evidence available at that moment, and nothing that arrived later. The candidates considered, including the ones dismissed in a sentence. For each candidate: the expected result, the confidence attached to it, and the cost in time and money. The route chosen, and the reason. What happened next. How the evidence changed the scientist’s view. These must be timestamped before the outcome, because hindsight turns uncertainty into inevitability. Disagreement also has to survive. Averaging three scientists into one clean rationale reproduces exactly the information loss we are trying to fix. But there is an obvious failure mode here. Once decisions are logged and scored, people log for the record post-facto. Anyone who has watched an electronic lab notebook fill up with retrospective tidying knows how quickly a research tool becomes a compliance exercise. A record that costs a scientist ten minutes of honest reflection per decision is worth far more than one that costs an hour of performance. A publication initiative called Registered Reports offers a useful starting point. Here, researchers submit their rationale, methods and analysis plan for peer review before the data exist, and the journal commits in principle to publish if they follow the approved plan. Nature has now expanded the format across every field it covers. This approach to paper writing timestamps intent before the outcome, but it freezes one plan. A useful search history must also preserve how the plan changed, which alternatives were rejected, when, and on what evidence. Subscribe Run the runner-up Autonomous labs show what happens when decisions and outcomes are connected in a loop. Liverpool’s mobile robotic chemist ran 688 experiments over eight days in a ten-variable formulation space. A batched Bayesian search used each result to choose the next experiments and found photocatalyst mixtures six times more active than the starting formulations. Every completed experiment changed what the system did next. The robot optimized within a goal and search space that humans had already chosen. It did not decide which scientific question mattered. So what this work demonstrates is narrower, but still useful: a search history pays off when the options return standardized outcomes quickly. Open-ended biology is harder because branches can take weeks and the discarded alternatives may never be run. Some exploration therefore has to be bought. Where two branches are plausible and the stakes justify the cost, a lab should sometimes run the runner-up. Otherwise the record captures what today’s scientists usually chose and stays silent on what they systematically overlooked. A funder could ring-fence a small fraction of a grant for the branch not taken, provided that the decision record and the outcome are both deposited. That costs money, but so does having every lab rediscover the same abandoned path. Test whether taste transfers When it comes time to evaluate if our new AI system exhibits taste, the comparison should run across laboratories and fields. At selected decision points in a live research campaign, we should freeze the six fields: the evidence, the candidates, expected results, confidence, costs and the choice made. Experts then rank the options before the outcomes are known, and those outcomes are checked independently later. We could give models one of two diets - papers alone, or papers plus decision histories - and ask them to rank the next experiment on unfamiliar projects. Then, we score information gained per dollar and week, calibration, and how quickly weak branches are abandoned. If histories improve choices only inside the lab that produced them, they amount to useful organizational memory. If they improve choices on unfamiliar problems elsewhere, Alasdair’s group will have captured something science has never managed to write down: a transferable record of taste. Until that happens, a scientific search history is a promising record, not yet a training set.

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Aug 13 • 11:16 AM EDT • Science • press.airstreet.com
Qlik Brings Governed Business Context and Analytics Workflows to Claude

Qlik’s MCP Server is now available through Anthropic’s Claude Directory, giving Claude users a simpler way to connect governed Qlik® data, analytical logic, and selected analytics and data workflows, so they can work with trusted business context instead of raw data alone. Key takeaways: Makes Qlik easier to discover and use inside Claude: Availability through Anthropic’s Claude Directory gives Claude users a more direct path to connect Qlik through MCP.Brings governed business context into Clau

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Oct 22 • 8:30 AM EDT • Business • finance.yahoo.com
What Does Anthropic’s Wet Lab Mean for Pharma?

Anthropic has established a wet lab in the San Francisco East Bay. In this article, experts explore what this means for scientific oversight, data ownership, and AI’s potential to transform drug discovery and rare disease research.

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Sep 30 • 8:00 AM EDT • Science • technologynetworks.com
Demystifying Anthropic's J-Space: A Mathematical Primer

Clarifying the math behind Anthropic’s representation workspace

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Sep 11 • 7:00 AM EDT • Science • towardsdatascience.com
Claude can now send emails in Gmail, even without your approval

Anthropic’s Claude AI can now take a huge step in your email inbox, with the ability to not only interact...

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Aug 18 • 5:20 PM EDT • Technology • 9to5google.com
Officials cheer Anthropic’s expansion in Manhattan

The maker of the Claude chatbot said it's doubling its New York City workforce this year, growing to about 1,000 employees.

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Jul 9 • 6:20 PM EDT • Politics • ny1.com
Novo Nordisk Taps Anthropic’s Claude Science To Speed Up Drug Discovery — Here’s Everything Investors Need To Know

Novo will use Anthropic’s Claude Science in R&D to tackle scientific and drug discovery challenges, aiming to develop new medicines faster.

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Sep 16 • 9:05 AM EDT • Science • stocktwits.com
Anthropic’s new Cowork tool offers Claude Code without the code

Built into the Claude Desktop app, Cowork lets users designate a specific folder where Claude can read or modify files, with further instructions given through the standard chat interface.

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Jan 12 • 2:30 PM EST • Technology • techcrunch.com
Anthropic’s Claude can now control your Mac, escalating the fight to build AI agents that actually do work

Anthropic has given Claude the ability to control a Mac, marking a major step in the AI agent race and raising new questions about automation, reliability, and security.

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Mar 24 • 4:00 PM EDT • Technology • venturebeat.com
The Market’s AI Fanfare Is Running Into a Harsh Political Reality

Anthropic’s hopes for a blockbuster IPO could depend as much on the ballot box as on investors.

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Jun 20 • 5:30 AM EDT • Politics • wsj.com
Anthropic’s Scare Tactics, SpaceX’s New Deal and Qualcomm’s Bargain | AI & Business for June 16

Plus, SpaceX’s Cursor deal, and AI struggles to replace stenographers

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Jun 16 • 12:05 PM EDT • Business • wsj.com
Hantavirus Scramble Tests Trump’s Overhauled CDC

Plus, Anthropic’s Mythos has thrown the White House AI strategy into chaos.

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May 8 • 7:01 AM EDT • Politics • wsj.com
Claude Science is Here, Antibiotics Designed by Text Prompt Among Applications

Basecamp Research’s antibiotic design and vaccine prediction AI models are now available through Anthropic’s Claude Science.

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Jun 30 • 6:11 PM EDT • Science • genengnews.com
5 takeaways from Anthropic’s big science event

The company rolled out a biology-centric version of Claude and hosted surprisingly forthright conversations about AI and science.

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Jun 30 • 10:00 PM EDT • Science • fastcompany.com
Anthropic’s breakout moment: how Claude won business and shook markets

Start-up’s bet on enterprise users is paying off as coding tools fuel revenue and investor frenzy

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Feb 6 • 4:00 PM EST • Business • ft.com
Anthropic’s Claude Can Now Autonomously Run Science Experiments With Lab Equipment

A new system allows agents to orchestrate complex experimental processes and extends Anthropic's reach into the physical world.

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Sep 4 • 3:08 PM EDT • Science • singularityhub.com
Anthropic’s life science plans; Novartis CEO on China deals; and more

Welcome back to Endpoints Weekly! We’re gearing up for a busy week of earnings coverage, as Moderna, AstraZeneca, GSK, Bristol Myers Squibb and more are set to report their Q2 ...

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Jul 25 • 6:00 AM EDT • Science • endpoints.news
Claude AI Shared Chats Reportedly Exposed in Google Search Results

Anthropic’s Claude share links appeared in public search results, raising fresh privacy concerns for users who shared sensitive conversations.

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Jul 26 • 1:05 PM EDT • Technology • cybersecuritynews.com
Exclusive | ‘Send Us More’: Anthropic’s Claude Sniffs Out Bevy of Bugs

New AI-powered tools are increasingly adept at spotting flaws. Hacking experts worry they will be good at exploiting them, too.

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Mar 6 • 5:30 AM EST • Technology • wsj.com
Coatue Projected $1.995 Trillion Valuation for Anthropic in 2030

In a presentation to prospective investors in January, Coatue offered a rare look at how it justifies Anthropic’s heady valuations. An anonymous source sent me the slides, which give a unique look at how a top investment firm values Anthropic’s business. This is a moment in time when some of America’s most valuable, growing technology companies remain private. In the January presentation, Coatue estimated that Anthropic would lose $14 billion in EBITDA on $18 billion in revenue in 2026, ending the year with $30 billion in annualized run-rate revenue. Most recently, it’s been reported that Anthropic is at $19 billion in ARR, which could suggest Anthropic is already running ahead of Coatue’s expectations. By 2031, Coatue projected that Anthropic would be generating $48 billion in EBITDA profits on $200 billion in revenue, with $224 billion of ARR. That would give Anthropic a 41x forward EBITDA multiple at a projected $1.995 trillion valuation in 2030. Coatue told the investors it was pitching that Anthropic could be worth $2.413 trillion in 2031. In February, Coatue co-led a $30 billion Series G investment in Anthropic that valued it at $380 billion. Coatue declined to comment on this story. I first shared this slide and talked about the presentation on my new podcast, the Cerebral Valley Show, which I host with my CVAI co-hosts Max Child and James Wilsterman. I’ve got a few other slides from the Coatue presentation for Newcomer subscribers.

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Mar 30 • 4:38 PM EDT • Technology • newcomer.co
Anthropic tells IPO investors US government actions could hit its business

Anthropic’s IPO prospectus warns that US government actions could harm its commercial customer and partner relationships, Reuters reports.

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Oct 2 • 10:19 AM EDT • Business • thenextweb.com
Anthropic’s $2 trillion problem: Its underlying business is nowhere near the IPO valuation it wants

Everything you need to know before you reach the office this morning.

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Aug 14 • 6:27 AM EDT • Business • fortune.com
SpaceX’s AI Business Waits for Liftoff | AI & Business for May 26

Plus, California studies AI job losses, Anthropic’s revenue soars and Nvidia plays the role of $5 trillion underdog.

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May 26 • 12:00 PM EDT • Business • wsj.com
Anthropic’s Claude Code and Cowork can control your computer

Its only a research preview for now.

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Mar 24 • 9:32 AM EDT • Technology • theverge.com
Some people's chats with Claude AI made publicly available online

Hundreds of conversations with Anthropic’s chatbot were discovered as being publicly accessible.

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Jul 27 • 5:51 PM EDT • Technology • bbc.com
Microsoft’s multi-agent AI system tops Anthropic’s Mythos on cybersecurity benchmark

Microsoft's new vulnerability-scanning system, codenamed MDASH, scored 88.45% on the CyberGym benchmark, surpassing single-model systems from Anthropic and OpenAI by using more than 100 specialized AI agents across multiple models.

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May 13 • 8:16 PM EDT • Technology • geekwire.com
1Password now lets Claude sign in to websites without seeing your passwords

1Password is launching a new Claude integration for Mac users today. It’s designed to let Anthropic’s AI agent sign in...

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Jul 16 • 9:00 AM EDT • Technology • 9to5mac.com
Claude’s voice mode is now available for Opus and Sonnet

Now you can chat with Anthropic’s more powerful models.

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Jul 23 • 3:00 PM EDT • Technology • theverge.com
Anthropic expected to IPO despite market uncertainty, AI slowdown calls

Wall Street is gearing up for Anthropic’s expected mega initial public offering, a major test of investors’ appetite for one of the AI industry’s leading firms. Just weeks ago, its CEO called for an industry-wide slowdown over growing safety concerns.

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Oct 5 • 5:00 AM EDT • Business • cnn.com
Anthropic’s Claude Science app is coming for Kendall Square

Few places on the planet have more at stake in AI’s transformation and disruption of life sciences than the Massachusetts biomedical ecosystem.

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Jul 13 • 12:50 PM EDT • Science • bostonglobe.com
OpenAI’s big Codex update is a direct shot at Anthropic’s Claude Code

Codex can now use your macOS apps on its own.

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Apr 16 • 1:00 PM EDT • Technology • theverge.com
Anthropic joins OpenAI's push into health care with new Claude tools

Anthropic’s new offerings allow users and providers to work with medical data, mimicking similar moves by OpenAI.

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Jan 11 • 5:00 PM EST • Health • nbcnews.com
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A trove of users’ seemingly private conversations with Anthropic’s Claude AI chatbot showed up in Google search results

The topics of the seemingly inadvertently exposed chats ranged from erotica, programming chats, work notes, and fake book reviews.

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Jul 27 • 1:20 PM EDT • Technology • fortune.com
How Dangerous Is Anthropic’s New AI Model? Its Chief Science Officer Explains.

Just how fast is the future coming at us, and how worried should we be? Last week, Anthropic announced Claude Mythos, the latest in what has become the leading family of AI models. In a very short time, AI models from Anthropic and other companies have become shockingly powerful at coding. But Mythos stands out because it is not just able to write code that can hack into critical systems, like those that run financial companies, but also to analyze systems and find and string together vulnerabilities in them, allowing Mythos to evade even sophisticated defenses. Anthropic chose to release Mythos to only about 40 leading corporations, so they could analyze the model’s capabilities and prepare countermeasures, in an effort it calls Project Glasswing. The release of Mythos—and the prospect of similarly powerful AIs to follow—has caused tremors at the top levels of Washington and corporate America. Jared Kaplan, co-founder and chief science officer at Anthropic, is at the center of this breakthrough. We sat down with Kaplan so he could walk us through just how powerful Mythos is, what the implications are for issues like our personal privacy, and what comes next. This conversation has been edited for length and clarity. Sean Fischer: For the layman, how is Claude Mythos different—more powerful, more dangerous—from previous models released by Anthropic? Jared Kaplan: I think most people have experienced the fact that our computers get faster and faster over time and over many decades. There’s this very smooth trend where every 18 months, maybe, computer processing power doubles. I think AI is on a trend in which it’s improving maybe 10 times faster than that. A lot of the earliest work that I did in AI was around identifying this scaling trend in AI. Claude Mythos is the latest model from Anthropic, but it’s not different because it’s qualitatively different. It’s really just kind of the culmination of the trend of AI models getting smarter and smarter at all kinds of general capabilities, from reasoning to software engineering to scientific research to knowledge work. For us, it was the first model to demonstrate very elite-level cybersecurity capabilities. It wasn’t because we trained Claude Mythos to focus on cybersecurity, but it was because, as a byproduct of its general intelligence and its general ability with software, it’s particularly good at identifying vulnerabilities in software and how to exploit them.

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Apr 15 • 11:40 PM EDT • Science • thefp.com
Trump Rejects Talk of A.I. Regulation and Calls Out Anthropic’s CEO

The president again rejected calls to try to regulate the industry, even as some of its leaders are speaking more openly about the risks of rapidly developing artificial intelligence.

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Sep 14 • 11:49 AM EDT • Politics • nytimes.com