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Home health worker crisis hurts Sarasota, Florida seniors

Tamara Bailey of Bradenton is among the dedicated Suncoast home health care workers who pursue their passion despite numerous obstacles.

Nov 8 • 4:00 AM EST • Health • heraldtribune.com

Scientists finally see hydrogen hiding between metal atoms

University of Sydney researchers have directly observed hydrogen dissolved between metal atoms in alloys for the first time, using cryogenic atom probe tomography with deuterium substitution.

Nov 8 • 3:22 AM EST • Science • bioengineer.org

UK HealthCare’s SMART Clinic offers support for addiction recovery, psychiatric treatment

By Dr. Danielle Anderson and Dr. Gopalkumar Rakesh University of Kentucky Asking for help with substance use can be difficult but figuring out where to turn for that help shouldn’t be.

Nov 8 • 12:34 AM EST • Health • nkytribune.com

Las Cruces seeks public input on homelessness, substance abuse and mental health Nov. 17

Las Cruces will host a Nov. 17 community listening session on homelessness, substance abuse and mental health at Central Elementary. Recording consent is required.

Nov 7 • 9:44 PM EST • Health • organmountainnews.com

Kaweah Health pushes for more OBs - The Sun-Gazette Newspaper

Kaweah Health works to recruit more obstetricians and expand maternity care services during nationwide doctor shortage

Nov 7 • 10:00 AM EST • Health • thesungazette.com

Whoa, I Missed It! Disney Starts Licensing the Household Silver, When IP Backfires, and More Big Content Moves

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Over these last few months, the entertainment business story landscape revolved around Skydance (and their merger) and Netflix (and their leadership shakeup). I don’t even want to scan my archives to see how many times I wrote about just those two companies over the last six months or so, let alone how many times they demanded their own article. Oh, how I long for June, when I could avoid them and write about other mergers and acquisitions (Comcast and NBCUniversal; Fox buying Roku). Well, not really, but you know what I mean. That focus on just two companies meant I ignored a lot of fun and, more importantly, important stories. So, it’s also time for another “Whoa, I Missed It” article. These are stories I wish I had written about, but aren’t exactly current events anymore. And there are a lot of them! Fifteen stories in all, including a very important merger that I didn’t write about, my word of warning about the IP deluge, how “genre” TV is making a big comeback, Netflix’s latest smart acquisition (and a licensing divorce), Disney and HBO’s recent TV show buys (and what they say about reboots on TV), a big cable merger, Amazon’s new bundle, social media censorship, and a lot more. Subscribe Most Important Story of the Week - Buy, Sell or Hold the Latest Content Development and Licensing in 2026!!! Content is king. I’ve written that before, and I believe in it now more than ever. If I had to quantify it, and I have, I put it at about 50% of the fate of any given media company, be they streamer, network, bundler, studio or social platform. This is a hits-driven business, and, as I like to do about every so often, it’s time to check in on the latest content moves. These content shifts on their own aren’t usually enough to be the “most important story” of a week, but if you add them up, you can see the content landscape shifting. The stories also fell into two natural buckets: licensing deals and IP moves. Plus, I’ll offer my “buy, sell or hold” rating for whether I think the deal is smart for a given side. Let’s dive right in. Disney Starts Licensing the Household Silver Disney is starting to license their core brands to Netflix. Quietly, over the last couple of years, Disney had rented some 20th Century [Fox] shows and films to Netflix, but until now, the core brands had escaped that fate. Now? At least some Pixar films will make it to Disney (including Elio) and some Disney+ Originals (like Percy Jackson and the Olympians). Here’s my rating for each company: Disney: Sell. One is tempted to say Disney has started licensing the “crown jewels”, but I don’t think we see that yet. I’d call this the “family silver” instead, which isn’t quite as valuable. That said, Disney’s new CEO clearly is focused on shoring up the company’s profitability, and that means licensing deals, even at the expense of Disney+ exclusivity. This could also help bring eyeballs to Percy Jackson for the upcoming season, a similar benefit to “dual casting” this show, which I also think Disney should do. Still, in the long run, I’d protect the core brands more. Netflix: Buy. This is a smart move, assuming the price is right, and I’d bet it is. (Netflix’s content licensing teams are some of the best in the industry.) Of course, this is another data point that Netflix is moving away from making their own films and relying on licensing instead. That has downsides—they’ll always end up renting—but if you’re buying Disney content, that’s a good move. Prime Video Buys More Live Events Amazon’s Prime Video/MGM Studios keeps purchasing live events, including the Emmys (which I wrote about here) and some regional sporting rights. These bolster their NFL, NBA and Academy of Country Music Awards licensing deals. My theory here is that Prime Video knows that they can sell the advertising for more on live events than on their massive acquired/original inventory of shows and films. (As I’ve been showing with Reelgood’s data, they have a LOT more shows and films than other streamers.) Advertisers want live, engaged viewers, since they’re a lot more likely to be real. Prime Video: Hold. I like Amazon’s focus on live events, but it remains tough to evaluate this company, er, business unit, since we don’t know anything about their financials. Yes, Amazon’s CEO recently released a very carefully worded statement about Prime Video, claiming profitability, but we don’t know by how much by when. (It’s also not audited by third parties, so we have to take it with another grain of salt.) Plus, given that Amazon increased the price of the Emmys by about a third, they also likely overpaid. (Maybe that’s why they’re barely profitable, allegedly.) But also, I think they know they need to dominate live TV, and that’s a smart strategy! So I’m torn, but lean towards calling this a smart move. The Emmys: Definitely sell! I mentioned this in my “Streaming Bonus Content” article, but I really, really, really, really do NOT like this move for the Emmys. Chasing short term dollars over long term awareness is not a smart move. To reach the widest audience, the “dual-cast” format—meaning broadcast and streaming—just reaches more people. Skydance Takes Its Animation Back This is the story that made me want to write a “let’s catch up on content” column in the first place. Specifically, Skydance and Netflix have ended their animated film output deal. It’s not huge, since really, what film has Skydance Animation made that’s broken out? But strategically, it shows you how Skydance is positioning their company. Skydance Animation: Hold. Again, I still need to see Skydance Animation put out a hit or two before I can judge this as a smart move. The other worry for Skydance is they have a lot of overlapping animation houses now, and that’s going to end at some point. Still, if John Lasseter can regain his animation mojo—and his track record has been mixed at Skydance, ignoring his other issues—this could be a powerful point for Paramount. Netflix: Hold (put your films in theaters). Right now, with the Dan Lin upheaval and Peter Rice coming in, we don’t really know what Netflix’s plans for theaters versus straight-to-streaming films are. So I need to see what new films (if any) they buy/rent/produce to replace the Skydance flicks, but it will probably be a smarter investment of capital, since the straight-to-streaming films have just failed to break out, outside of one major example. Theaters: Buy! They do look like they’re gonna end up with more inventory based on the Skydance move, and now Netflix putting four to five films in theaters per year. For example, Netflix confirmed that KPop Demon Hunters 2 will come to theaters, and that’s going to be a smash. Disney+’s Reboot Future So those were the major licensing news stories, and now we get to the IP-related updates. Obviously, I’m generally pro-IP in content development. But that’s not some iron law; not all IP hits equally. Get ready for Entertainment Nuance Guy. And let’s start with a big worry. Scanning the news stories, Disney has three reboots on their lineup between ABC, Hulu and Disney+: Coach (on ABC), The X-Files and Glee. So are reboots as immune to failure as IP? We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out about… Why I’m skeptical about some upcoming genre and IP plays… How Skydance’s merger closing unlocked Paramount and HBO… The focus on “genre” across the streamers and studios… Some big creators leave Netflix… Netflix’s horror TV show licensing play (and what they should have done instead)… A huge merger that I didn’t write about... Whether or not we’ll see a major film tax credit… Amazon’s new megabundle of streamers… And (somehow) more… ...please subscribe! We can only keep doing this great work with your support.

Nov 6 • 2:02 PM EST • Entertainment • entertainment.substack.com

Discord is about to get way, way faster on your Android phone

A new Discord update built on Rust is substantially reducing the amount of RAM it uses, leading to significantly faster loading times

Nov 6 • 1:13 PM EST • Technology • 9to5google.com

Gut microbe-made metabolite UDP-GlcNAc hijacks the host "sugar-switch" (O-GlcNAcylation) to fuel breast tumour progression and chemotherapy resistance

Graphical Abstract: Ruminococcus lactaris in the gut synthesizes UDP-GlcNAc, which enters the circulation and activates the host enzyme OGT. OGT-mediated O-GlcNAcylation stabilizes transcription factor NFIB, which upregulates OGT and the proto-oncogene KIT, forming a positive-feedback loop that drives breast cancer proliferation, invasion, migration, and paclitaxel resistance. Inhibition of OGT blocks this pro-tumor axis.

Nov 6 • 12:46 PM EST • Science • eurekalert.org

This gen’s top 10 PlayStation Studios games

As we near the six-year anniversary of the PS5, we thought we’d dive into our estimates for the top-grossing PlayStation Studios games since the start of the gen. Together, the 10 games we’re covering today have generated over $6.5 billion across PlayStation (84.7%), Steam (14.1%), and Xbox (1.2% via just Helldivers 2). Let’s have a look at the top 10. Spidey and Kratos sequels take the top two spots God of War Ragnarok takes the top spot with $1.4B in revenue via 21.6M copies – 20.1M on PlayStation (75.2% via PS5) and the rest on Steam. Around 27.5% of the copies sold on PlayStation were physical. It’s another PlayStation evergreen seller, too. This year, Ragnarok has already sold 1.1M copies, generating $60M (68% on PlayStation), outperforming new 2026 titles like Gears of War E-Day and Saros. Overall, our estimates show that Ragnarok has been accessed by 6.7M PlayStation Plus players (it was added to the Extra tier about two years ago). So it’s performed that well this year despite subscription cannibalisation. That’s the pull of God of War IP. And that Bautista series on Amazon is going to be massive - bigger than Fallout, I reckon. Next up is Spider-Man 2 with $1.3B across PS5 (over $1.2B) and Steam (nearly $70M). Spider-Man 2 has sold over 19.1M copies overall, so it should pass 20M early next year. Spider-Man 2 is an evergreen title that always spikes around the holidays (mostly concentrated around Christmas week): In December 2023, it sold 2.1M copies, up 20% from November 2023 (the month after release) In December 2024, Spider-Man 2 sold 460K copies (natural decay), up 60% from November 2024. Despite the Steam version launching in January 2025, it still sold more copies – and made more revenue – the month before. In December 2025, it sold 328K copies, up 30% from November 2025. This year’s December and Christmas will be somewhat limited by Spidey’s February 2026 addition to PS+ Extra, where 6.3M people accessed it for the first time. While subscription inclusions always cannibalise premium revenues to some extent, Spider-Man 2 did manage to sell 578K copies in August 2026 – the most its sold since Q1 2024, following hype from the Spider-Man Brand New Day movie. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe God of War Ragnarok and Spider-Man 2 continue to be huge evergreen tentpoles for Sony. Together, both titles have sold 3.4M this year (2.3M for Spidey and 1.1M for Ragnarok), generating a combined $172.9M ($115.8M for Spidey and $57.1M for Ragnarok). Again, some premium games would take a leaf out of Kratos’ book (not Spidey’s!) and would kill for these numbers in year 1. And we can see why Sony wants to take a leaf from Steam’s book, killing physical to get higher margins from catalogue sales, ensuring they get their cut, and having more control over supply and demand (and pricing for their first-party titles). Hot rods, hellpods, and horizons Gran Turismo 7 takes #3 this generation with $841.9M in revenue via 12.7M copies sold. For more info on GT7, you can check out our write-up from earlier this week. Around 1.1M people have already played GT7 this month, less than six days in. Next up – at #4 – is the first second-party game on this list. Helldivers 2 has generated $786.3M via 23M copies sold across Steam (66.1% of the copies), PS5 (25.7%), and the 1.5-year-later Xbox port (8.3%). And there are plenty of players very dedicated to the Super Earth cause, as over 4M folks have played Helldivers 2 for over 100 hours, while 462K played for over 500 hours. That dedication to democracy is pretty topical… Anyway, Helldivers 2 still attracts about 700K players per day (more if there’s a significant update), and its August addition to PlayStation Plus Extra has led to 1.6M new players overall. This year, Helldivers 2 has sold over 2.5M copies, generating $81.1M in revenue. It’s another evergreen hit for Sony, and draws in engagement numbers similar to Arc Raiders. The Helldivers 2 model, in my opinion, should be the way PlayStation approaches its live-service and second-party releases. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Horizon Forbidden West rounds off the first half of the top 10, generating $485.8M. That said, PlayStation completely stifled Horizon Forbidden West’s revenue by adding it to PlayStation Plus way too early (one year after launch). You can see the revenue drop-off clearly in our platform: As you can see: Forbidden West was still a healthy catalogue earner right before it was added to PS+ Extra, making about $1.23M a week on PlayStation across late 2022 and into January 2023. After it was added to Extra_, Forbidden West_’s weekly revenue halved to around $610K, basically overnight. Excluding launch month, Horizon Forbidden West generated about $67.2M on PlayStation in the period before the PS Plus addition. In the same period after it joined the service, that fell to $28.1M, a 58% drop. So, PlayStation didn’t trade a little bit of premium revenue for subscriber value here. It gave up well over half of it, and it cut momentum instantly for one of its premier franchises. Could you imagine the kind of cannibalisation if it launched day in date on Extra? Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe And the cannibalisation wasn’t a temporary blip that bounced back once the game left the service in September 2024. By then, 19 months on PS Plus had already hoovered up most of the install base that would have bought it, so there was barely a premium audience left to monetise. PlayStation even added it back to PS Plus on October 21 this year, and sure enough, weekly revenue dropped again (by around a third); though, the numbers are small now that Forbidden West is nearly four years old. Worth the trade-off. The usual suspects, platformers, and an Asia-driven second-party hit As for the rest of the list: Ghost of Yotei has now generated $410.1M via 5.5M copies on PS5. Yotei popped off a bit a few weeks ago due to a content update, which we covered here. The Last of Part Us I, a remake that we covered here, has generated $341.3M in revenue (67.2% via PlayStation) via 6.4M copies. It was also added to PS+ Extra about two years after launch, where 7.8M people accessed it for the first time. Ratchet and Clank: Rift Apart has made $334.9M (93.6% via PlayStation 5). It’s now passed 5M copies sold overall. It’s sold 250K copies this year, generating $13.5M in revenue. Time for another Ratchet? Stellar Blade has generated $316.9M via PS5 (59.7%) and Steam (40.3%). However, the share of Stellar Blade’s 5.4M copies sold is far closer (50.4% on PlayStation, 49.6% on Steam) – despite the Steam version releasing a year later. China, Taiwan, and Hong Kong account for 48% of Steam copies and 35% of PlayStation copies (about 41% overall). These markets are regionally priced lower than others, hence the difference. Astro Bot rounds out the top 10 with $292.6M in revenue via over 4.7M copies sold. We covered Astro’s recent performance here, covering how Astro Bot is another evergreen seller and has been a hit with families. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Even these bottom five games have generated a combined $281.7M this year in catalogue sales. PlayStation wants those numbers to be bigger in the coming years, which is one of the reasons it’s killing the disc (alongside the better margins it and publishers get through digital). No more used discs means more D2C revenue for PlayStation. On that note, we recently chatted to the New York Times again about PlayStation’s digital future, so keep your eyes peeled for that! The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. Want to see why these companies (and many others) are subscribed to Alinea? Get a free platform trial! [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]

Nov 6 • 10:43 AM EST • Technology • alineaanalytics.substack.com

Marine and energy insurers set for steep reinsurance rate cuts

Asia-Pacific marine and energy insurers face substantial reinsurance price cuts at upcoming renewals after a prolonged period of benign losses and with ample capacity in the market…

Nov 6 • 9:04 AM EST • Business • businessinsurance.com

Still searching for a Zelda 40th Anniversary Switch 2? Nintendo has good news

🥳 Nintendo confirmed Zelda 40th anniversary celebrations will continue into next year, suggesting ongoing Switch 2 restocks 🚨 Want the Zelda Switch 2? Follow our Zelda Switch 2 restock tracker @mattswider on X and we’ll send out an alert when stock appears 🙏 Unlike other limited editions, the console is not expected to have a restricted production run 💰 The special edition costs $519.99 for its ornate design, but does not include the Ocarina of Time remake 🙌 Nintendo President Shuntaro Furukawa ruled out future console price increases due to secured memory supply Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 Restock Dashboard: Get our live, audible siren alerts The Legend of Zelda 40th Anniversary Switch 2 is hard to find right now, though we’re doing our best to help people get one using our exclusive restock tracker. However, there is some good news to share. 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 Subscribe Nintendo has provided an update that suggests the console will be easier to obtain in the future. Speaking during Nintendo’s financial results, president Shuntaro Furukawa said that The Legend of Zelda’s 40th anniversary celebrations will continue into next year (thanks, Stealth40k). That strongly suggests that the Zelda Switch 2 console will continue to be restocked, and that it won’t be constrained by a limited production run. Unlike the Xbox Series X25 limited edition – where only 25,000 units have been produced – the Zelda 40th anniversary Switch 2 should be more obtainable once the initial demand from buyers dies down. Of course, whether you can wait as long as next year to get hold of the Zelda Switch 2 is one thing, but knowing that the console will eventually become more widely available should please those who are worried about missing out. The Legend of Zelda 40th anniversary special edition Switch 2 costs $519.99, but doesn’t include a copy of The Legend of Zelda: Ocarina of Time remake. You’re basically paying a $20 premium over the standard Switch 2 for the beautiful ornate design. Luckily, it sounds like the price of the Switch 2 will remain at $499.99 for the foreseeable. Furukawa ruled out any future price increases as Nintendo has managed to secure sufficient quantities of memory. That also means the price of the Zelda Switch 2 won’t be affected. Up next: Zelda 40th anniversary Switch 2 restock: here’s when Target should have stock Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.

Nov 6 • 8:43 AM EST • Technology • theshortcut.com

What many get wrong about Amish or Plain Anabaptist communities, measles, and health

The U.S. has reported three measles deaths this week in three different states. All the affected were unvaccinated, and some were too young to get vaccinated, relying on herd immunity. Many states haven’t seen a measles death in more than 30 years. Measles is highly contagious, but it mainly spreads among those without immunity. Social factors typically shape these unvaccinated pockets. Many states describe these deaths as occurring among “under-immunized, rural communities.” (In the future, it could be among other tight-knit groups.) Small signals in the news point to many outbreaks right now among the Plain Anabaptists (APA), which include communities like the Amish and Mennonite. Many know APA communities from a distance through their bakeries, furniture, and roadside buggies. But most of us don’t know enough about them, their traditions, or how those traditions actually interact with health and disease. Rumors, misconceptions, and frustration fill those voids. Tristan Sharratt, a family nurse practitioner and rural health researcher who grew up near and works with these communities in Central New York (and a YLE reader who reached out!), says misconceptions continue to create major problems. If the U.S. wants to stop a tsunami of measles coming down the pipeline, or even support health in those communities proactively beyond measles (which is ideal), we must understand how specific communities protect themselves, their values, and the role broader society plays. This starts with a conversation and some self-reflection. Here are the top five lessons I learned from my conversation with Tristan.

Nov 6 • 8:34 AM EST • Health • yourlocalepidemiologist.substack.com

Salt Substitutes Can Soon Replace Sodium in Everyday Foods—and Help Lower Blood Pressure

The FDA recently ruled that salt substitutes can replace salt in certain foods. Here’s how that will impact your health.

Nov 6 • 7:00 AM EST • Health • verywellhealth.com

Bausch Health's Gastroenterology Business, Salix, to Present New Data on Cirrhosis Trends and Severe Alcohol-Associated Hepatitis at The Liver Meeting® 2026

Bausch Health Companies Inc. (NYSE: BHC)(TSX: BHC) and its gastroenterology (GI) business, Salix Pharmaceuticals, will present a research poster at the American Association for the Study of Liver Diseases' The Liver Meeting® 2026, November 5–9 in Denver, Colorado. The study highlights the substantial mortality and rehospitalization among patients hospitalized with severe alcohol-associated hepatitis (AH).

Nov 6 • 7:00 AM EST • Business • finance.yahoo.com

Eugene home hit while resident slept inside; Asian-American business owners report theft

Another targeted burglary has been reported, according to the Eugene police Department.At 10:05 p.m. October 30, Eugene police responded to a neighborhood near

Nov 5 • 7:59 PM EST • Business • kval.com

Influence Media Wraps Its $600M+ Anthem Entertainment Deal

Influence Media Partners has officially wrapped its more than $600 million deal for 'substantially all' the assets of Anthem Entertainment.

Nov 5 • 7:43 PM EST • Entertainment • digitalmusicnews.com

New Gastonia youth behavioral center to offer mental health support, substance-use prevention

Facility to offer mental, emotional help to children & adolescents

Nov 5 • 6:30 PM EST • Health • wbtv.com

Shopping center near Foundry Park sells for $67.8M after healthcare revamp

Chicago-based Novak Development sold the Webster Place shopping center for nearly $68 million after landing an Advocate Health facility as a major tenant.

Nov 5 • 6:26 PM EST • Business • chicagobusiness.com

A sweeter future? AI helps scientists discover new sugar substitutes

Researchers Dr. Shayma El-Atawneh and professor Amiram Goldblum at the Hebrew University of Jerusalem have developed a new computational framework that identified 92 promising candidates for future sugar ...

Nov 5 • 12:40 PM EST • Science • phys.org

New center at MHAST provides mental health and substance use crisis services for the community

The center had its ribbon-cutting ceremony on Tuesday, Oct. 20, and is fully open and accepting individuals experiencing mental health and/or substance use crises.

Nov 5 • 10:37 AM EST • Health • wbng.com

Heichal HaTorah Talmidim Experiment in the Science Lab

This past week, Heichal HaTorah’s ninth-grade biology students learned how to use indicators to test the pH levels of common household solutions. Students observed a wide range of colors as natural plant-based pigments (anthocyanins) in red cabbage juice reacted with acids and bases in everyday substances. Students made predictions and determined whether a substance was […]

Nov 5 • 7:49 AM EST • Science • jewishlink.news

Imaging Science Thesis Defense: A Step Towards Developing Digital Twins of Forest Environments with Terrestrial Laser Scanning | Events

Imaging Science MS Thesis Defense A Step Towards Developing Digital Twins of Forest Environments with Terrestrial Laser Scanning Zoom Link here Aisha Co Imaging Science MS Candidate Rochester Institute of Technology Abstract: Digital twins have become an increasingly relevant topic as we pursue accurate representations of the real world for planning, research, and even design purposes. This study focuses on the steps for creating digital twins of forest environments using sparse points from terrestrial light detection and ranging (LiDAR). Specifically, we developed geometric models of structural digital twins (SDTs) from leaf-off terrestrial laser scanning of real-world forests. Three algorithms were used to develop an approach to handle individual tree reconstructions for sparse point clouds, and they were tested and validated with a two-sample Kolmogorov-Smirnov statistic against an existing inventory of the RIT Nature Trail to evaluate the reconstruction’s fidelity. The key evaluation metrics included diameter at breast height (DBH) and height. The limited nature of available ground truth necessitated the use of an additional validation method using a PANGAEA open dataset, based on comparing DBH, height, and crown diameter against the dataset’s calculated measurements. Reconstructions were compared against per-tree reference values at two-point spacings for sixteen trees from the open BR07 dataset (PANGAEA); these specifications matched the collected RIT Nature Trail data and the scanner’s nominal spacing. On BR07, the proposed method had the lowest median DBH error among the methods that modeled every tree (1.28cm, 4.1%), and this error was nearly unchanged at the coarser spacing, while TreeQSM’s rose from 4.2% to 6.5% and AdTree overestimated DBH by 30% to 40%. Results show the proposed method understates the tree heights by 0.2m to 1.4m but contains the least error when estimating DBH. The proposed method was able to produce all 69 trees, while SimpleTree produced 49 and none at the 4.35 cm BR07 spacing. We concluded that the developed geometric model (digital) twins have significant potential to serve as both simulation and prediction tools. We recommend that future efforts focus on collecting per-tree ground truth measurements within the scanned plot and incorporating leaf-on scans. Leaf-on scans include representative foliage, which would add realism to the model and ecological function of the trees. Intended Audience: Beginners, undergraduates, graduates. Those with interest in the topic. To request an interpreter, please visit myaccess.rit.edu

Nov 5 • 1:50 AM EST • Science • rit.edu

Traditional Korean paper becomes breathable patch for future wearable health care

Wearable health-monitoring devices are becoming increasingly important for personalized health care, but conventional patches often rely on substrates that restrict airflow, trap sweat and cause skin ...

Nov 4 • 5:00 PM EST • Health • phys.org

BayMark, Bradford and Deerfield Execs Talk M&A in 2027

This is an exclusive BHB+ story. Activity in the addiction treatment and substance use disorder markets has been trepidatious throughout 2026 as

Nov 4 • 4:57 PM EST • Health • bhbusiness.com

BayMark, Bradford and Deerfield Execs Talk M&A in 2027

This is an exclusive BHB+ story. Activity in the addiction treatment and substance use disorder markets has been trepidatious throughout 2026 as

Nov 4 • 4:57 PM EST • Business • bhbusiness.com

UT Health Sciences Advisory Board to Hold Fall Meeting Friday, Nov. 13

The UT Health Sciences Advisory Board will meet Friday, Nov. 13, at 11 a.m., in the Mooney Library, 875 Monroe Ave., on the Memphis campus.

Nov 4 • 3:00 PM EST • Health • news.uthsc.edu

Traditional mulberry paper used to develop breathable health patch

Wearable health-monitoring devices are becoming increasingly important for personalized health care, but conventional patches often rely on substrates that restrict airflow, trap sweat, and cause skin discomfort during prolonged use.

Nov 4 • 1:14 PM EST • Health • news-medical.net

Uneven And Fragile Progress Against Neglected Tropical Diseases

While substantial progress has been made in driving down the global burden of neglected tropical diseases (NTDs), trends are “uneven and fragile”, and

Nov 4 • 9:00 AM EST • Health • healthpolicy-watch.news

HOMETOWN HEALTH: Cannabis involved in most substance-related ER visits for teens, study finds

Cannabis-related emergency room visits also are rising among adults ages 19 to 24.

Nov 4 • 8:09 AM EST • Health • wdbj7.com

Major Changes to Hemp Regulation Are Taking Effect: Is Your Business Ready?

The hemp industry is preparing for significant federal restrictions that will change which hemp-derived products can legally remain on the market, with key provisions taking effect in November and December. At the same time, states continue to take different approaches to intoxicating hemp products, creating added complexity for manufacturers, retailers and consumer brands.

Nov 4 • 7:00 AM EST • Business • dentons.com

The dangerous myth of the well-meaning health guru

In healthcare, a warm heart is no substitute for a trained mind. Banned Australian naturopath Barbara O’Neill built a global empire on the defense that she "just wants to help," but good intentions mean nothing when uncredentialed health advice causes real-world harm.

Nov 4 • 12:00 AM EST • Health • acsh.org

AFGHS co-signatory countries ask health care users to help fill the financing gap

Hundreds of thousands of Ugandans living with HIV on antiretrovirals could be targeted for user fees or community health insurance schemes requiring modest premium payments, according to the April 2026 version of the country’s America First Global Health Strategy implementation narrative.1 As part of the “sustainable financing for the private not for profit sector” strategy, 491 facilities will be targeted for a phased introduction of user fees and scale up of community health insurance programs.2 In the Ugandan context, PNFP facilities include faith-based hospitals and other health facilities, US missionary organizations and centers of excellence—services that are often co-located at government facilities but run with additional financial and technical resources. 402,000 people—or about 28 percent of the total Ugandan adult PLHIV population on treatment—get ART from the private not for profit sector. The selected facilities provide the majority of ART and prevention of mother to child transmission (PMTCT) services. The plan doesn’t give the total number of clients served by the 491 facilities, so it is not possible to give a precise number. But the majority of 402,000 is a figure in the hundreds of thousands—hence the estimate I’m using.3 The April draft of the Ugandan implementation plan narrative is the only one I’ve been able to review. But the government of Uganda is not alone in turning to health care users to help fill the financing gaps caused by the abrupt withdrawal of US funds. In July 2025, the Government of Liberia introduced user fees for previously free services including “registration, accommodation, patient feeding, hospitalization, and a wide range of surgical and diagnostic procedures.”4 Earlier that year, Liberia rolled out a revolving drug fund designed to stabilize drug supplies by “allowing patients to pay a small fee for standardized, quality medications,” according to a Ministry of Health press release.5 (Both of these approaches had been proposed in the National Health Policy 2022-2031; media coverage explicitly connects the launch with the US foreign aid cuts.) The health financing strategies proposed by Uganda and established in Liberia are qualitatively different from user fees officially adopted by specific health facilities to cover funding shortfalls caused by the new US approach.6 The latter is a stopgap, adhoc change. The former is a national governmental adoption of policies that pass costs on to health care users, despite evidence that such approaches can exacerbate inequities and leave deficits unfilled. Two countries does not make a pattern, but they do point to urgent questions: Have other countries, including Liberia, included user fees or community health insurance schemes in their implementation plans? If so, do any of these narratives have what Uganda’s lacks: a fall-back plan in place in case these strategies for sustainable health systems fail to deliver—as they have before? I wonder if you think about it Subscribe Predictable pitfalls Both community-based health insurance and user fees are as old as the hills. And after decades of people climbing up these hills, duking it out, climbing back down—neither strategy has shown the results the Ugandan implementation plan is counting on. This is, in fact, a hill some folks are willing to die on. (You knew I’d get there, right?) In November 2025, an African-led team of health system experts published a paper directed at low- and middle income country governments trying to figure out how to create self-sustaining health systems. The money wasn’t coming back. It had been more than nine months since the season of freezing, waivering and wood-chippering; two months since AFGHS tumbled into the world touting co-financing requirements and reductions in future US government health aid. Governments were looking for strategies for sustainable, self-financed health systems, the authors wrote. For countries considering user fees and community health insurance to fill the financing gaps, they had a simple message: Don’t. On user fees, the paper states: “Reliance on user fees is ultimately a regressive and inequitable approach. It places a disproportionate burden on the poor and undermines health system goals of equity and financial protection. […] There is overwhelming evidence that user fees mobilise very limited resources for the public health sector, making it an inefficient mechanism for revenue mobilisation.” On community health insurance: “Attempting to shift the burden of funding previously donor-funded services, such as HIV care and management, and TB treatment, onto contributory schemes would exacerbate their fragility and fail to protect the population.”7 The WHO says that community-based health insurance “cannot be expected to provide a major source of funding or coverage,” and noted that most schemes offer only moderate benefit to individuals paying into them, and exclude the poorest segment of the population.8 And yet, the US-Ugandan implementation plan says that community health insurance is “the central pillar of this [PNFP] sustainability strategy” and that this approach that will generate “pre-paid pooled funding at facility and community level [that] improves financial risk protection for households, reduces catastrophic out-of-pocket expenditure, and generates structured, transparent revenue streams that can progressively absorb recurrent costs including health worker salaries.” Unfortunately, Uganda’s own history suggests the pillar might not be able to bear this weight. Ugandans Have Been to this Rodeo Before—and Some Want Their Money Back Uganda introduced its first community health insurance scheme in 1996 with support from international donors.9 Thirty years later, somewhere between 0.2 and 0.3 percent of the population is covered by CHI; just over 1 percent has any kind of health insurance.10 User fees were universally introduced in 1993 as a condition of a World Bank loan.11 They were abandoned in 2001, and in 2004—the year I moved to Uganda to watch the free HIV program get underway—a definitive study found that the fees did not improve health systems and outcomes.12 In 2004, most clinics and hospitals had ‘free’ and ‘fee for service’ options for getting care.13 The fee for service, or “cash and carry” programs had often been established in the years prior to PEPFAR and the Global Fund to Fight AIDS, Tuberculosis and Malaria. People who could afford to paid for the drugs, often at facilities in the private-not-for-profit (PNFP) sector. When free drugs arrived, some people who’d been paying kept on doing so, perhaps because of shorter wait times, greater confidentiality, convenience or other factors. But in the year that I spent visiting the same clinics around the country week after week—including a “center of excellence” that maintained separate days for cash and carry clients and those accessing free ARVs—lots of people who had been paying tried to switch to the free option. They’d paid because they had no other choice. They’d sold pieces of family land, begged family members for loans, bought pills by the week, and sometimes by the day. Or they were just cash-strapped, like most of us, and wanted the funds for other things. 14 Twenty-two years later, this hasn’t changed. Ugandans pay out of pocket for 30-40 percent of their health care costs, leading one paper to declare that “falling ill is more than a health crisis. It is a financial emergency.”15 One recent study found that up to 48.5 percent of households dealing with tuberculosis sold something, took out a loan or dug into savings to defray the costs of TB care—which is supposed to be universally free.16 The Ugandan implementation plan does anticipate challenges. It proposes a phased approach, with 187 facilities introducing user contribution systems in Year 1, 152 in Year 2, and 153 in Year 3. Willingness to pay and feasibility studies will precede roll out; fees will be tiered by region, and a waiver system is proposed to ensure that no one has to pay who is unable to. Moreover, the plan provides for quarterly reviews of epidemiological data to “ensure that user contributions do not compromise epidemic control gains, ART continuity for the client cohort, TB case management, or PMTCT services.” Alt text: A screenshot of a table included in the implementation plan narrative that is the subject of this stack. It’s got a fetching pink bar at the top. It uses the abbreviation “CHI” which is Community Health Insurance, and FBO which is Faith Based Organizations, and it details the number of facilities that will implement user fees with waivers and community health insurance schemes over the five years of the agreement. As I said in the footnote, this is a super interesting document with a lot of other rich material. Tell me what you see—and what you would have focused on. And if you’ve seen something like this, or anything else that strikes you, in another implementation plan, tell me that too. You can use the Substack message platform or try me on Signal at @endaplague_again.25 (because @mercoonfan was, weirdly, taken). But the plan doesn’t fully explain what will happen if this approach doesn’t work out. Yes, progress will be monitored, and corrective action triggered. However, there is no specified funding replacement if premium and fee revenue prove inadequate. Instead, the authors write, “Currently, COEs serve a total client cohort of over 180,000 across 28 facilities. In the initial years, the U.S. Government (USG) will provide financial support for clients; over time, user fees generated by COEs will become the primary source of funding for sustaining their services.” Failure does not really seem to be an option. Health insurance schemes are more acceptable to the Ugandan population than user fees. Members of Parliament and civil society traveled to Ethiopia to see how that country’s scheme worked. In a follow up report, a veteran civil society group recommended allowing the “health insurance ecosystem to grow organically and [to] keep reviewing the law and regulations as this growth takes root.”17 One study found that more than three-quarters of Ugandans were willing to join a health insurance program.18 However, coverage of community-based health insurance is minimal, as is coverage of any kind of insurance—including private plans.19 A national health insurance scheme bill has been stalled for several years and presently sits with President Yoweri Museveni.20 Community-based health insurance scheme that do exist are expanding in number, but losing enrollees. Between 2022 and 2026, the number of community-based health financing schemes across the country increased by 42 percent, while the number of people enrolled decreased by nearly 11 percent.21 None of this means that community-based health insurance should not happen in Uganda—or that people do not want insurance. It doesn’t even mean that user fees and waivers won’t ever work. But there is highly relevant evidence from Uganda and the surrounding region that it is quite optimistic to describe community health insurance and user fees as central supports for sustainable financing in any sector of the health system. And now for the best-case scenario In the best-case scenario22, the Ugandan approach does exactly what it sets out to do, and so does the Liberian fee structure and revolving pharmacy fund—though I’ve not confirmed that these are in the MoU. In one best-case scenario, Uganda is an outlier, and user fees and community health insurance are not recurrent pillars of self-sustaining financing in other countries’ implementation plans. In another best-case scenario, all countries that include these strategies enjoy success beyond anyone’s evidence-informed wildest dreams: reliable funding generated by health care users fees, great health care outcomes for everyone, no exacerbation of inequities, no crippling household debt. No sold land, repurposed school tuition or high-interest loans. In the best-case scenario, not one of the hundreds of thousands of Ugandans living with HIV receiving antiretrovirals from 491 PNFP facilities misses a refill or leaves care because of user fees or community health insurance premiums. This is the best-case scenario for these people for their own health, and for their families. It is also the best-case scenario if Uganda wants to stay on the path to eliminating HIV as a public health threat. According to the country’s most recent data, 96.5 percent of people living with HIV on antiretrovirals are virologically suppressed. Epidemic control depends ensuring that 95% of people living with HIV know their status, 95 percent of those individuals are on ART, and 95% of those individuals are virologically suppressed. Uganda is still struggling with the first “95"—a frankly abysmal 85.3 percent. If HIV epidemic control and the attendant prevention of new infections, avoidable suffering and premature death matter, the country cannot afford to lose any clients who are currently in care.23 As I write this a couple hours before the polls close for the US elections in the city I live in, I say with soul-deep sincerity: I am rooting for the best-case scenario. I think it’s safe to say that we all are.24 I think it’s also safe to say that if the US and co-signatory governments have inked plans that lead to successful expansion of community health insurance and strategic use of user fees, we all would like to know, now, so that we don’t miss the opportunity to celebrate when success happens. The implementation plan narratives have to enter the public domain. They are the fullest expression of a strategy co-created by two governments. There are assumptions and details that people living in the US and co-signatory countries need to understand that are not available in the MoUs or, to date, in the Congressional Notifications. Some of these details can help other countries that are, as I write this, still working on implementation plans. Others, like a solid count of how many other countries have plans for expanding user fees or health insurance, are important for regional and global health architecture reform initiatives. No matter how this election night turns out, there will be a slew of new Congressional member orientations, briefings and talking points papers in the next few months. Release of implementation narratives should be a bullet point in every context that AFGHS is discussed. These documents can be redacted so that procurement sensitive information isn’t disclosed. There is much more historical precedent for sharing such documents than there is for relying on user fees to fill health financing gaps. Let’s look at the information together so we can hope for the best and prepare for, you know, the other thing. Alt text: A substack first: a bicep selfie! It’s my arm - peachy-white skin, black shirt (flannel, notch neck, too hot for this appallingly balmy November weather, if you’re wondering) and a sticker that says I VOTED 2026. Beige letters on red for I voted. Beige on blue for 2026. You bet I did.25 In your wildest dreams. Subscribe 1 This is a really, really rich 95 page document. There are fascinating ideas and detailed plans in it. It is all worth reading AND I have, in this post, highlighted an instance of content that could pose challenges and certainly posits success of strategies that haven’t worked before. I would love to hear what readers’ see that’s interesting and should be lifted up as something to check for in other implementation plans. I will also shortly be adding a static page to the substack site where implementation plan documents will live. I will put the url into this footnote and it will also be there on emilybass.substack.com by the end of the week. Uganda Implementation Narrative Section 4 April 22 2026 Draft 1.51MB ∙ PDF file Download Download 2 User fees are costs charged for visits, labs, medicines or other health services, usually at the time they are provided. Community health insurance, or community-based health insurance, is what the World Health Organization calls “micro insurance,” which is health insurance targeted at low-income people. 3 As usual (by which I mean always), please prove me wrong. 4 https://smartnewsliberia.com/liberias-ministry-of-health-announces-2025-hospital-service-fees-for-public-facilities/?utm 5 https://moh.gov.lr/news/2025/grand-cape-mount-leaders-residents-embrace-new-community-pharmacy-program/?utm 6 https://www.christianitytoday.com/2026/09/hiv-usaid-pepfar-africa-foreign-aid-cuts-mission-hospitals/?utm 7 https://gh.bmj.com/content/10/11/e021270 8 https://www.who.int/news-room/fact-sheets/detail/community-based-health-insurance-CBHI 9 https://pmc.ncbi.nlm.nih.gov/articles/PMC2827475/ 10 https://pmc.ncbi.nlm.nih.gov/articles/PMC10861328/#b3-jpmph-23-110 11 https://pmc.ncbi.nlm.nih.gov/articles/PMC527704/ 12 Same citation as the footnote 2 - the article is called “Learning from failed health care reform in Uganda.” To which I say: If only. If. Only. 13 There is a whole taxonomy of user fees to be aware of, if not commit to memory. Out of pocket costs are everything that someone pays for themselves. In this Stack, user fees are planned and policy-supported out of pocket costs. There are also out of pocket costs that people pay to buy drugs or receive tests or health care assessments that would be free if the drugs were on the shelves, or the machines or kits were available, or the staff were on site. A user fee is usually designed to be modest, pegged to willingness to pay, and may be waiveable at the point of care for anyone who is unable to do so. The costs for things that would otherwise be free are whatever the market will bear and people either have to pay them or go without. Out of pocket costs for services and stuff that aren’t available in public facilities are different again from bribes or unofficial fees that some health workers may impose, even though most are indefatigable, tireless and tired, and devoted to their clients. 14 For the record—which really is these footnotes—I would give a whole stack of fridge magnets for a systematic analysis of the economic and social impact of the Mass Unemployment Event in AFGHS countries among the very people who used to be able to afford and cover user fees, both for themselves and vast family networks. Locally employed USAID technical staff, house cleaners, caregivers, drivers and technicians were financial anchors for cousins, friends, friends’ children, friends’ childrens’ cousins, teachers, pastors, neighbors and so many other kinds of kin. Aid recipients lost direct funding; many other people who had not been aid recipients, but parts of the elaborate care webs that function as safety nets for so many people, lost crucial support too. And that’s even before we get to the people who worked at the hotels and restaurants and bars where people employed by the US and its implementing partners used to spend disposable income. Those businesses have lost revenue; those folks have lost jobs. It will be some time coming—and someone will have to fund this work—but I do hope it happens. And I hope, as usual, to be proven wrong. 15 https://eprcug.org/blog/how-out-of-pocket-healthcare-costs-keep-driving-ugandans-into-poverty/ 16 Another straight-to-the-point journal article title. Households experiencing catastrophic costs due to tuberculosis in Uganda: magnitude and cost drivers. https://pubmed.ncbi.nlm.nih.gov/32938411 17 https://www.cehurd.org/download/technical-policy-brief-on-community-health-insurance-scheme/?wpdmdl=13661&refresh=6ae9122f5d4ed1793659439 18 https://pmc.ncbi.nlm.nih.gov/articles/PMC10125197/ 19 https://pmc.ncbi.nlm.nih.gov/articles/PMC10861328/#b3-jpmph-23-110 20 https://ugandapost.news/uganda-to-make-health-insurance-mandatory-by-2026/ 21 https://shu.org.ug/download/235 22 With a nod, tip of the stack hat, and wag of the Mercoon tail to a deeply valued reader who told me that I have a tendency to speculate about the worst-case scenarios a little too much of the time. 23 https://news.mak.ac.ug/2026/10/uphia-2025-shows-ugandas-hiv-status-awareness-gap-despite-strong-treatment-outcomes/ As you’ll see in the next footnote, I’ve already written a subSubstack on another topic, so I will be brief with regard to the study referenced in this article. The Uganda Population-Based HIV Impact Assessment, or UPHIA, will never happen in this way again. For more than a decade, PHIAs have been supported by the US government as a way to generate accurate estimates of country progress on key HIV indicators. They are a holdover from the PEPFAR program that was laser focused on ensuring US taxpayer dollars subsidized progress in pandemic control. There may be other population-level surveys and the data may even be publicly released, as the entire set of FY2026 MER data have not. But PHIAs will never happen again. If you’re wondering whether the estimates of HIV progress at country level might get less reliable….you’re not alone. 24 Ooh baby, I hate “we” in almost all forms. But sometimes I go there, when I am looking for company, which I am. Because this Stack moves into the somewhat-uncharted territory of assessing what the implementation plan narratives may suggest about co-signatory countries’ roles and responsibilities to the people living within their borders. The MoUs, specimen and data sharing agreements were templates. Countries’ answers fit into pre-specified questions that did not include, “how are you going to fill financing gaps and stabilize your health system as this plan unfolds?” In contrast, the implementation narratives are open form—the product of co-creation between the two governments. Co-creation can mean lots of things, but nothing leads me to believe that implementation plans are ghost-written by the US government, or that contents were imposed by the US counterparts. Instead, I think the parts of the plans that read like country government initiatives are endorsed, if not initiated by, those governments. For instance, the Ugandan implementation plan narrative describes plans for revenue-generation through fees charged for equipment calibration, repair and maintenance provided through Uganda’s National Equipment Calibration Laboratory, and laboratory accreditation through the Uganda National Accreditation Service (UGANAS), targeting private sector, PNFP, research and academic clients. That’s super specific and also quite ambitious. It doesn’t read like an American idea. There’s also a provision for solar panels, and other stuff that feels country owned and driven. This is where it gets interesting. If co-creation is the case, then both the US and co-signatory governments are accountable for the contents and the outcomes. Most discourse about AFGHS to date has focused on the decisions that America has made, or demanded that other countries make. The AFGHS architects have monopolized the hot seat. As they should, in so many ways. America absolutely created the conditions under which countries needed to come up with health financing strategies to fill unanticipated, catastrophic funding gaps. And with not-too-long a lens, we can look back and see that America is also on the hook for its role in the Bretton Woods institutions that made user fees and health system fiscal austerity conditions of loans during the era of structural adjustment. But in the here and now, it is not at all clear to me that the US is requiring Uganda or any other country to implement specific approaches to sustainable financing. Instead, it is as the authors of that paper up in footnote 6 suggest: African governments have agency. As implementation plans roll out—whether or not the narratives are shared—it will be important to understand what this agency looks like and what it means for people, including the poorest of the poor. And it will be important to figure out how to talk about it safely, respectfully and critically in places other than the literal and metaphorical footnotes. 25 This week’s song is “Once upon a time” by the Moody Blues. (I know, this is gonna be a weird, largely banger-free end of 2026 playlist. HMU with requests.) AND please do watch the video and appreciate the truly amazing opening sequence—a drum kit wasteland, a coupla plastic bags, a bit of sand. Sort of like the hill where fiscal austerity policies that put costs on health care users might go to perish. But then there’s a lady with amazing hair. It’s worth it.

Nov 3 • 11:57 PM EST • Health • emilysbass.substack.com

‘Money Out of Politics’ ballot measure passes, constitutional convention fails

Proposal 2 on Michigan ballots, the “Michiganders for Money Out of Politics” initiative, has passed. The initiative will alter state campaign finance law to ban campaign spending from “regulated electric and gas utilities, contractors with over $250,000 annually in government contracts, and people and organizations with substantial connections to those utilities or contractors.”

Nov 3 • 9:58 PM EST • Politics • michiganadvance.com

The Last Disney+ Original?

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Before we get going, I wanted to remind readers about how I plan to keep your trust while I add advertising to this newsletter. As you’ve no doubt noticed, I’m running ads now, but the danger is that it could impact my analysis and writing. I have a list of sponsors on my About Page, so if you think I’m biased, you can check out who’s sponsored this newsletter! This is something that I’m not sure anyone else in digital media does (if you’re a writer or media outlet and you do this, let me know and I’ll shout you out!) but it’s something I’d love to see embraced by the entire industry. Sunlight, i.e. transparency, is often the best disinfectant. Okay, on to this week’s issue. We (finally) have another major Disney+ TV show to talk about, so that’s my main focus for today. Plus, we had a lot of new shows come out, including the fourth seasons of The Diplomat and Tulsa King! And Love is Blind! The Lowdown! Also, four (four!) straight-to-streaming films came out this week, featuring a lot of big names and celebrities, so I’m going to look at those. All that, mixed news for the WNBA, Reacher ends its run on the charts, Skydance does well in September viewership, NYU’s Sundance dominance, all the flops, bombs and misses, and a whole lot more. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the weeks of October 12th to October 18th, 2026. You can find a link to my terminology here.) Subscribe Television - Disney+’s Porridge Problem Listen, per my headline, VisionQuest isn’t the last Disney+ Original. At least, I’m pretty sure it’s not. They have other MCU shows in development. Well, maybe one: But it sure feels like the end of an era. I’d call it their “porridge too hot” era, to quote myself from The Ringer. I told Ben Lindbergh that Disney+ seemingly couldn’t figure out the right amount of content. In the heights of the Streaming Bubble Era (circa 2019 to 2022), they started releasing an insane amount of TV shows. After their growth slowed, they’re down to two or three shows a year, and that might be down to 1 by 2027. Here’s my TV shows by year chart: Even at the time, I thought Disney was making too many shows (that cost too much). Today? They’re definitely making too few shows (though the budgets are more in check, at least according to the reporting). Porridge too hot, porridge too cold; too many shows, now not enough. Which makes evaluating VisionQuest so interesting. This show didn’t have a great lead-in, whether it be a Marvel Cinematic Universe film (the last non-Sony-produced-Spider-Man flick came out The Fantastic Four from July of 2025) or Marvel Cinematic Universe TV show (the two this year were Wonder Man back in January and _Daredevil: Born Again_in May, both of which underwhelmed). And so far, VisionQuest hasn’t quite recaptured the MCU Originals glory, but it has some signs of sparks. First, it made Samba TV, though at a lowly ninth place. At least it made it, a feat some other Marvel shows didn’t accomplish. (Ironheart landed on the Samba TV charts one week at tenth place, but Wonder Man and Daredevil: Born Again both missed.) VisionQuest also made Luminate, though with only 3.0 and 7.6 million hours. But it missed Nielsen in its first week. The best news might be its 7.8 on IMDb, on 12K reviews so far, great numbers, even for a superhero show. Looking at those numbers, this show will really need to pick up in future weeks—and it may since it’s coming out weekly—or Disney will have another disappointment on its hands. Disney+ binge-released their last few shows to try to boost numbers, but that meant shows like Iron Heart and Wonder Man didn’t last long on the charts. _Daredevil: Born Again’s_last season missed entirely (though it came out weekly). Here’s the Disney+ Originals by totals: And for a fun new look, here are those same shows, rearranged by the years they came out: That really shows that, in addition to Disney+ releasing fewer shows, those shows just don’t hit like they once did. If I had to offer one main explanation, it’s that Marvel Studios moved away from characters who starred in the Avengersmovies (The Scarlett Witch, Vision, Hawkeye, Loki, Falcon, Winter Soldier) to characters who didn’t (Moon Knight, She-Hulk, Iron Heart, Wonder Man, Daredevil). It sounds trite, but more popular IP tends to do better than less popular IP. In Marvel’s case, beloved, decades-old characters trump newer ones. And yes, I think this is a problem for Disney. The failure of Marvel TV shows to linger for weeks on the charts, unlike in 2021 and 2022, explains why Disney’s share of the charts has plummeted: That’s a strategic issue. Yes, these shows are really expensive, but without them, Disney+ will struggle, especially if Disney+ keeps raising prices AND licenses out its shows non-exclusively. My recommendation? Return to the core value proposition, which is Disney+ as “genre HBO”. The goal is six shows a year, coming out weekly, spaced out throughout the year. When a show hits, keep it coming back. Make three to four of those shows Marvel or Star Wars, and fill out the rest with IP swings like Percy Jackson, Goosebumps or something like National Treasure. And make YA-skewing shows like Coven Academy to fill out the schedule. Disney, you can get this porridge just right, er, make the right number of shows. Quick Notes on TV Netflix’s sophomore, er, junior, er, senior season slump abated very, very slightly this week. I speak of The Diplomat, which returned for its fourth season on 15-Oct. Credit where credit is due, this show debuted in April of 2023, and has put out new seasons every year since. Has that helped the viewership? Not really. This season opened to 16.4 million hours, which is down significantly from the first season (21.7 million hours) and down somewhat from the second season (18.0 million hours), but it is up from last year’s 14.2 million hours opening. On Samba TV, it opened to third place; that’s also very good. On Luminate, it opened to 25.0 million hours, which is good, but over thirty million hours is a hit on that platform. Netflix wisely renewed it, since it’s steady and, frankly, Netflix needs hits.1 Paramount+ put out Tulsa King’s fourth season on a Friday. After putting out most of their big, usually-Taylor Sheridan-scripted shows out on Sundays last year, they’ve clearly moved to Fridays going forward. Was this a thought-out strategic change, Netflix mimicry, or a data-inspired move? Tough to say. Fridays are crowded with new movies, but so are Sundays with new shows. Anyways, this one is coming out weekly, and we haven’t seen it hit the Nielsen or Luminate charts yet. But it did make Samba TV at fifth place, which is a good opening. Still, if this doesn’t make Luminate or Nielsen next week, I’d call it a disappointment. Netflix had two unscripted shows hit the charts this week, one a docu-series and one a reality competition show. Tyson is a four-episode docu-series about one of boxing’s most popular fighters, and it made both the Samba TV and Luminate charts, but not Nielsen. That’s a solid run for only four episodes (assuming it didn’t cost an arm and a leg to produce). Netflix’s latest season of Love Is Blind also returned for its eleventh season, which opened to 10.0 million hours, down from previous seasons. It also had 11.0 million hours according to Luminate, roughly in line with the Nielsen numbers. Last issue, I analyzed the triple successes of Below, Carrie and Crystal Lake, noting that all three have done well. I mostly used Nielsen, but all three shows also made Samba TV (see above). Crystal Lake in particular did very well on Luminate, getting 35.0 million hours, top for Peacock among first seasons: The top “show” of the week would have been Thursday Night Football again, at 41.7 million hours. This is still above last year’s game, but it continues the season’s overall downward trend, which happens every year. (Though a big week is coming, based on the news stories I’ve seen.) As I said before, I’ll do a deeper dive on all the October games later this month, with comparisons to previous years. One company is quietly on a roll, when you consider the shows it makes and streams. I speak of Skydance—a point Variety made—noting that it produces Neagley and Reacher for Amazon, along with Paramount+’s Lioness, which means it produced three of the top four shows of September according to Nielsen. By the way, Neagley fell off the Nielsen charts after four weeks, which is a pinch short for how well it started, but it’s still a huge success. (Interestingly, it finished just 7.3 million hours ahead of the cancelled Ride or Die.) The point, though, which I’ve made before, is that Prime Video still has a problem with how many co-productions it buys, most notably _The Boys_from Sony and Reacher/Jack Ryan from Skydance. It’s not a critical flaw—everyone licenses shows—but Amazon still struggles to make its own hits. Reacher finally fell off the Nielsen charts, so here’s its final rank for season four: We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… ...An example of the algorithm NOT picking a film… …whether or not Netflix buys shows simply for the movie poster… ...if East of Eden is above the Obliterated Line... ...what four star-studded straight-to-streaming films didn’t chart... ...and a whole lot more... ...please subscribe! We can only keep doing this great work with your support. If you want an idea of just how much content you’d get in a full issue, check out this older issue.

Nov 3 • 7:03 PM EST • Entertainment • entertainment.substack.com

Phantom Blade Zero made $223M on Steam and PS5 in five days

Phantom Blade Zero was always going to be a hit. We’ve been banging on about it for months now. Well, the results are in, and Phantom Blade Zero has indeed been a hit. Yesterday, S-Game reported that Phantom Blade Zero has sold 4M copies. As of this morning, our estimates show that Phantom Blade Zero has generated $223M via 4.3M copies sold across Steam (3.1M) and PlayStation (1.2M). This instantly makes Phantom Blade Zero this year’s #10 new 2026 game by premium revenue across Steam, Xbox, and PlayStation – and without an Xbox release to boot. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe Combined, China, Taiwan, and Hong Kong account for 55% of Phantom Blade Zero’s copies sold – 56% of copies on Steam and 50% on PlayStation. But revenue is slightly different. Phantom Blade Zero actually made more revenue outside of China However, due to regional pricing, China, Taiwan, and Hong Kong account for a lower share of revenue, 45%. The three countries account for 40% of Phantom Blade Zero’s revenue on PlayStation, and 47% on Steam. This is due to regional pricing, which you can easily check in our platform: Using the $59.99 USD base price as a starting point, we can see that Phantom Blade Zero costs the equivalent of $40.31 in China (-32.8% of the US price) and $41.80 in Hong Kong (-30.3%). So while Chinese culture is at the heart of Phantom Blade Zero (in terms of theme and player base), it’s actually making more money in non-China markets. In fact, markets outside of China, Hong Kong, and Taiwan account for $123M in Phantom Blade Zero revenues via 2M copies. Even when we remove revenues from these markets from the analysis, Phantom Blade Zero remains a top 20 new 2026 title by revenue across Steam, Xbox, and PlayStation. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe In other words, Phantom Blade Zero is a global hit. It’s not all China – or even majority China, when it comes to revenues. The China spring board helped, but a successful State of Play and – more importantly – positive reviews helped this one land in other markets. Quality sells. China was hyped from the start, but Western players needed more convincing As we wrote back in August, China was always going to show up early for Phantom Blade Zero. Our daily Steam revenue data shows just that, and we can see when S-Game’s banging RPG won over players outside of China: On the day Phantom Blade Zero’s Steam pre-order button went live in mid-August, China accounted for nearly 70% of Phantom Blade Zero’s Steam revenue. The shares hovered around 68% throughout August. This is the hometown-hero effect we’ve covered in the past, with the home market committing first – almost sight unseen – on national pride and a lush-looking trailer alone. Then things get even more interesting. Following the State of Play on August 18, US daily revenue more than doubled (from $72K to $146K), China’s daily take nearly quadrupled ($237K to $892K), and the rest of the world’s revenues also more than doubled. As China spiked so much harder than the others, its share of revenue hardly moved, holding at around 68%. So the by-all-counts-awesome State of Play got non-China markets and the West interested (you can see daily spend jump), but it didn’t move the needle for overall revenue shares. Positive reviews were the Western tipping point. US daily revenue went from $106K on October 25 to $230K when the embargo lifted on the 26th, to $463K on the 27th, to $899K on the 28th. So nearly 8.5x more revenue in four days, boosted by the positive reviews and subsequent word of mouth. When Phantom Blade Zero launched on the 29th, things hit critical mass. On launch day, the US and the rest of the world combined out-earned China for the first time in Phantom Blade Zero’s whole pre-order history. You can see this unfolding pretty nicely in the revenue shifting shares, too. China’s lifetime revenue share sat at 68% in August and was still 65% as late as October 25th, but it dropped to 45% by November 2. Over that same period, the US nearly doubled its share from 10% to 18%, and the rest of the world climbed from 25% to 38%. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe That’s not to say that China sold less – far from it. The West and non-China markets just showed up later, won over by the reviews and word of mouth. However you look at it, Phantom Blade Zero has become one of this year’s highest-grossing premium games. Daily volume seems to be decelerating a bit (which is natural), so subscribe below for more updates on performance. Speaking of performance and deceleration… Gran Turismo 7 is one of PlayStation’s biggest earners While games like Ghost of Yotei, Helldivers 2, Astro Bot, Wolverine (2.7M now, by the way), and even Marathon and Saros tend to get all the headlines (we hold our hand up there, too!), there’s one PlayStation game from the past five years that’s earned more than all of these games: and it’s one that’s rarely talked about in enthusiast circles. Gran Turismo 7, which launched in March 2022, has sold 12.7M copies. This amounts to $840M in revenue, second only to Spider-Man 2’s $1.3B – if we’re talking PlayStation first-party for this generation. Gran Turismo 7 still brings in around 3M players every month (and between 400K and 700K active players per day). It’s also an evergreen seller every year. For example, Gran Turismo 7 generated: $189.7M in 2023 via 2.9M copies $161.3M in 2024 via 2.7M copies $119.1M in 2025 via 1.7M copies This year, Gran Turismo 7 has already sold 1.3M copies, generating $74.7M And there’s more laps to come Every December is comfortably GT7’s biggest month of the year (except launch), and the gap is widening there. December generated 2.1x a normal month in 2023, and by 2025 that had grown to 2.8x. Want more free estimates and insights in your inbox twice a week? Subscribe below! Subscribe As the typical months cool off with age, Christmas always holds strong, so the holiday period is becoming a bigger slice of Gran Turismo 7 yearly revenue. For Gran Turismo 7, the week around Christmas does 3x to 5x a typical week – three years running: Christmas week 2023: $14.7M (4.6x the year’s median week) Christmas week 2024: $9.3M (3.3x) Christmas week 2025: $8.5M (4.6x) These Christmas peaks happened at the full $59.99 (Gran Turismo 7 wasn’t discounted at all in December 2023 or December 2025). And although there was a discount late in December 2024, GT7’s peak week that year still happened at full price. You can really see why PlayStation hasn’t added this one to PlayStation Plus, eh? Say it after me: Subscriptions cannibalise premium revenue! On that note… Let’s take a quick look at how Gran Turismo 7 is doing versus its nearest competitor, Xbox console exclusive and long-running sim racer Forza Motorsport (released in 2023 as a reboot for the franchise, about 19 months after GT7). Forza Motorsport has sold around 1.3M copies across Xbox (75.4% for Xbox console and PC) and Steam (24.6%), grossing $89.9M across those platforms. Launch aligned, and on just PlayStation, Gran Turismo 7 had sold 10.2M copies, generating $676.1M, by that point. In other words, Gran Turismo 7 has sold the same number of copies this year as Forza Motorsport has sold since launch. When all is said and done, Gran Turismo 7’s 2026 revenues will have lapped Motorsport’s lifetime, too. It’s worth noting that Forza Motorsport was not released on last-gen consoles, and under a quarter of Gran Turismo 7’s revenue has come from PS4 consoles. Critically, Forza Motorsport is also on Game Pass, where nearly 7M players have accessed it. Meanwhile, the Forza Horizon series has been performing incredibly in terms of revenue. This year’s Forza Horizon 6 has generated $583.7M across Xbox and Steam despite Game Pass cannibalisation, and last year’s Forza Horizon 5 PlayStation port has generated $383.5M on PS5 alone. So two questions, then: How well is Forza Horizon 6 going to do when it launches on PS5 in January? Hit subscribe to get that in your inbox in January (which is in two months somehow!?) Subscribe 2. Open-world arcade Gran Turismo when? Also, if you like arcade racers, go and play Star Wars Galactic Racer. It rules. Like GOTY material, seriously. The last word Reply to this email – or reach out here – if you have any feedback for the newsletter – or want to request a game for us to cover. [Alinea Analytics boasts the most accurate PC and console estimates in the business. Game makers use our platform to understand their audience, keep an eye on the competition, monitor sales trends, and spot new opportunities. We equip game studios and financial institutions with accurate data and the confidence to make smarter, data-driven decisions. Want to talk about all things games market data? We’d love to chat!]

Nov 3 • 12:39 PM EST • Technology • alineaanalytics.substack.com

Why ‘Star Trek’ isn’t the ultimate in optimistic, Up Wing science fiction

Right there in the first season of Star Trek: The Next Generation—episode 17, “When the Bough Breaks,” to be specific—we get a classic Up Wing line from Captain Jean-Luc Picard, played by Patrick Stewart, who died last week at age 86. When Lieutenant Commander Data (Brent Spiner) says breaching a planetary force field might be “impossible,” Picard curtl…

Nov 3 • 11:42 AM EST • Science • fasterplease.substack.com

Russia's Poorer Regions Facing Brunt Of Health-Care Cuts As Military Spending Soars

Russia plans to reduce funding for key federal health-care programs in its 2027 budget. With medical services already difficult to access in many regions, the proposed cuts are raising fears that patients will face greater obstacles in obtaining treatment and essential medicines.

Nov 3 • 10:00 AM EST • Health • rferl.org

OpenAI: ChatGPT Search Is About 20% of Google’s, 250 Million People Speak With ChatGPT, and Chat Is Merging With Work

OpenAI says ChatGPT growth is accelerating. The company added 200 million users over just the past two months, jumping from 1 billion to 1.2 billion weekly active users in 60 days. Its search volume, it says, is approximately 20% of Google’s. Its users create 1.5 billion images with it per week. And its voice mode, between dictation and speaking with ChatGPT, now has 250 million combined weekly active users. ChatGPT consumer product lead Adam Fry told me this during a brief fireside chat at an OpenAI-hosted dinner in New York City on Monday night. “The growth is just going big,” he said. During our conversation, Fry also revealed plans to merge ChatGPT’s Chat and Work modes (so that confusing toggle up top will soon go away), agreed with feedback that ChatGPT-created restaurant signage looks too uniform, and addressed the cost to serve its personal assistant Dots. Here’s a look at our full conversation, lightly edited for clarity and length. We also cover image generation, interactive interfaces, advertising, education, and public unease about AI: Alex Kantrowitz: OpenAI has analyzed ChatGPT’s search volume and compared it with Google’s. What did you find? Adam Fry: ChatGPT has been growing quite quickly. ChatGPT’s volume of search-like queries is now roughly one-fifth the volume of queries of Google. It’s a pretty amazing statistic when you think about it, mainly because we started just about a year and a half ago. It’s hard to remember this, but ChatGPT at a time didn’t have any up-to-date information. You’d ask a question, it would say something like, “It’s past my training date,” and nobody had any idea what that meant. You’re saying ChatGPT’s search volume is one-fifth of Google’s. Bing’s share of the search market is around 5%. Does that make you multiple times larger than Bing? To say that more directly, ChatGPT has gone from one billion to 1.2 in just the last two months. That’s roughly 100 million users in 30 days, and another 100 million in another 30 days. The growth is just going big, and we’re staying very focused on how fast ChatGPT is growing. What counts as a search? I might have 20 prompts back and forth in a ChatGPT conversation. Does each one count as a query? Story continues below… A MESSAGE FROM OUR SPONSOR Move upmarket without a rebuild Moving upmarket means saying yes to what enterprise buyers ask for first: SSO, directory sync, and audit logs. WorkOS gives you all three, so your team keeps building the product instead of the checklist. Get enterprise-ready. Continued from above…. Adam Fry: What people came to ChatGPT for to start, if you go back about two years, is really writing help and coding help. Those wouldn’t be things that you really search for. What we’ve seen over the last year is people have grown into all these other topics. Things like you’re looking up a person or people or a place or a thing, and it requires up-to-date information. That’s a key element. Another big part is finance questions or health questions, where you really want to make sure it’s up-to-date information that’s quite factual, and we’ll do a web search for those questions. It’s basically anything that a user would have traditionally gone to a traditional search engine for, but is now deciding to go to ChatGPT for. Does each conversation with a search embedded count as one search, or does every question that requires a web search count? Every time you ask a question and go search the web, that’s a search. You used to work at Google. How would you say the nature of search is changing? One of the things that people really love about ChatGPT is this personalization and this understanding of the broader journey. If you look in the past, people would go for a Q&A box, and you’d ask a one-off question, like how tall is the Eiffel Tower. But there’s so much context in our lives around, “Maybe I’m taking a trip to Paris.” It’s actually helpful for ChatGPT to respond, “Here’s how tall the Eiffel Tower is, but I know you’re going on a trip to Paris.” It’s that ability for people to actually maintain context over time that has led them to start using ChatGPT in this way. You’ve also announced 250 million weekly active users of voice input, including dictation and conversations with voice mode. We are at 250 million weekly active users. What’s amazing about this is, if you look at those 250 million, what we’re seeing is it’s actually also incremental to the product. It’s no longer just a novelty. People aren’t just trying out voice. We’re seeing them use voice input day to day in their daily life, and it’s grown so quickly. Those 250 million users are using voice input, and that could just be a quick question or a long conversation. We’re seeing both behaviors. We’re seeing people just not want to type. You just hold it and start talking to it, or it turns into a longer conversation where people just sit with it. The big reason for this is the frontier capabilities of our models that we’ve shipped. We shipped what we call GPT Live 1, and then we shipped GPT Live 1.1. The big change with this is that it’s much more natural to speak with. It’s something we call backchanneling and interruptibility. Mhhhm… What you just did there is what the model does, because it’s really good at having a bidirectional conversation. That push to the frontier—we were the first to really release this at scale—has made it so much more natural for people to chat. That’s still only about 20% of the user base. From the outside, that looks small. Why is it exciting from the inside? It’s very exciting for a few reasons. We see from the data that when people start using voice, they stay around using voice. One of the things, transparently, we can do a better job of is bringing more people into discovering it. We see that the number of people who discover it could be a lot higher. But once they do, it’s a really new way for people to interact with AI. We’ve made a lot of improvements to it too, where we’re just going to see the number go up. You have background mode, so now by default, if you close the app, it’ll show, “Hey, the conversation’s still going.” If you want to walk around the house or you’re putting away the groceries, you can still have a chat. That kind of continuity has also changed how much people use it. Dots launched on September 29 and is about a month old. How’s it doing? It’s doing great. We talk to people about their Dot, and the first thing that everyone says is, “I love my Dot.” One of the reasons we’re seeing this is the proactivity, its ability to reach out to you and figure out things. The biggest use case I see all the time is, “Did I forget something today that I was supposed to do?” You can just say to your Dot, “Remind me of things at the end of the day that I may have forgotten. Somebody emailed me or messaged me,” and it’ll do that. This Dot changes the paradigm of the relationship with AI, where it’s actually helping you and giving you time back. You’re more conservative with permissions than some competitors. I tried to give my Dot my credit card, and it wouldn’t take it. With the creator of OpenClaw in-house, why are Dots’ permissions more limited? This is a space where we want to be very thoughtful and conservative because it’s a new space where you’re entrusting your Dot to take care of things on behalf of you that matter and are meaningful. We’ve just talked about how you go to this 1.2 billion user growth and asking questions. Now we’re asking people, “Can you ask ChatGPT or your Dot to help get things done?” But when you ask it to help get things done, it’s a whole new level of trust. We’ve built up a tremendous amount of trust in giving the right answers to your questions, and we want to make sure that when we build this new product, it has a high degree of trust. It’s a long game. We think this is going to be a new market for a very long time, and we want to make sure that we’re being this trusted player in the market to start. I initially thought Dots would be available on my $20 plan, then realized I had to spend $100 a month to get it. I upgraded, but I’d like to downgrade at some point…. We hope to keep earning your business and make the value good enough. It’s a really good point. ChatGPT’s goal more broadly, which I think is unique for us in the market, is we are focused on bringing intelligence to everyone safely across the entire world. For Dots in particular, there’s no difference. We don’t have anything to share tonight about the date of when Dots will go to a broader set of users. But you can rest assured we’re working very hard, and there are a couple things we have to get right. Over time we’re going to work on more efficient, agentic models that are able and capable of doing things for you. The first one is, right now we wanted to make sure that your Dot is actually really helpful. We started with some of our best models, but over time we’re going to work on more efficient, agentic models that are able and capable of doing things for you. The second thing is around proactivity. We’re still dialing in: How much do I message you to help you get things done? We can always play around with that to understand how much usage should a user use to have a successful Dot. We’re going to work on both, and our goal and ambition is to bring it out to all users. How much background computing does a Dot require? I’ve read estimates that serving a $100 subscriber might cost OpenAI $3,000 in compute, and mine seems to read every email that arrives. How often is it checking connected data sources? Right now, Dots are on the compute-heavier side, and this is one of the things we want to make sure that we can dial back over time. But the goal is to give you the best product. This is our premium, always-on personal assistant. Once we nail that, we’ll figure out how to dial back the compute needs. The thing we’re seeing also from our models, as we train frontier models, is just how—I can’t even keep up with how quickly we have a new model, and each new model is more efficient. If you looked at 6.1 Sol when it came out relative to Astra, much more efficient. I’m very excited about the next set of models we have coming too that’ll be even more efficient that we can use. Elon Musk said the cost of serving Grok Bot was unsustainably high relative to revenue. Is efficiency the key to winning against competitors, or is there more to it? There are a couple of factors that go into it. One is the cost side, but the other is the revenue side. On ChatGPT and on our consumer business, we’ve been extremely proud of our ability to diversify different revenue streams in a way that’s growing really fast. To give you another stat, we announced several months back that we had passed 50 million subscriptions, and the number has grown considerably since then. On ads, within 200 days, we reached more than a billion in ARR, and that business is growing extremely quickly. We also have credits. Rather than paying for subscriptions, users can buy more credits. Between credits, subscriptions, and ads, I’m confident that the value of a Dot is going to be able to pay for itself. Elon has subscriptions too. This is clearly an expensive product to serve. One thing we continue to bet on at OpenAI and ChatGPT more broadly is that the models will continue to get much better and much cheaper, way faster than any of us think. If you look back at the historicals on it, it continues to be true. From what I’ve seen, I see no slowing down of that. What is Meta doing right with Muse? It has spent a lot of time atop the App Store charts. There are a couple of things they’ve done well. The first is people have been craving simplicity in their products. One of the things we have stated publicly as well is, at times AI products can be too complex. We’ve announced we’re merging ChatGPT’s Chat and Work. We’re making it much more simple in the products. You don’t have as many toggles or sliders between efforts and different model pickers. One of the things they’ve done well is this simplicity. You just go in and you can ask a question. You don’t have to think too much about what you’re doing. That’s one thing that seems to have resonated with users, which we also believe in. Second, there’s something really nice about being able to access your agent across many different channels. We just announced and launched Dots on iMessage. Whether you talk to your Dot on email or iMessage or within the ChatGPT app, the ubiquity in getting your assistant out there is going to be key. Those are two things that, if I had to be nice to our competitors, I would say were two big ones. So Alexandr Wang’s meme-tweeting strategy isn’t something you’re going to emulate? I have a different tweeting style. ChatGPT still asks me to choose between Chat and Work, even though some people call this technology AGI. Will that distinction go away? Couldn’t agree more. We have to solve this. Asking users to choose — we’ve heard repeatedly from all of our users it’s too much to understand. When should you go to Chat? When should you go to Work? It’s solvable. There’s real research to solve to make sure the models can understand what your intent is. Are you asking for a fast, quick reply? Are you asking me to go do a long agentic task? We’re going to solve it, and the plan is to bring Chat and Work together. So one interface will work out whether I’m asking for a conversation or a task. When? Coming soon. You told me the majority of ChatGPT’s 1.2 billion users are using image functionality. What are they doing? Today, 1.5 billion images are created per week. It’s hard to even wrap my head around that number. They’re doing a wide range of things. One of the most interesting things they’ve started to do is really use it for productivity use cases. The first thing it started with—I don’t know if you saw the ’80s trend, but it was quite fun. You could take a photo of yourself and say, “Put me and my family in ’80s outfits.” I did this for my family, and it was a really fun poster. But what we’re also seeing is businesses for their menus, or posters for birthdays. People are using it almost in a productivity-like fashion to create visual diagrams of what they would like to see. We’ve actually brought the latency down on images as well, so it’s gotten a lot faster. It went from a very high number of seconds to getting much faster. As it comes down even further, the number of images people are creating and the number of use cases is going to grow a lot. My feature request: When a restaurant makes a menu or sign, prompt it for more specificity so it doesn’t look like every other AI-generated restaurant sign. Or offer a shuffle button for a different style. I agree with the feedback, and we’ll take it to the team. I’m seeing ChatGPT generate little interactive interfaces within its answers. What’s the direction for Intelligent UI, and how are people using it? I am extremely excited about Intelligent UI. If you go back a couple years, these chat apps were all text, and now that’s changing. They’re going to be visuals. Intelligent UI and our first attempt at this with GPT-6 Intelligent UI is really just the beginning. As you go to the extreme, what you can imagine is, let’s say you’re using voice mode, and you just say, “Show me how offside works.” Immediately it should show you a visual diagram, and you say, “No, I don’t quite understand it.” It should just repopulate. That’s where the future of this technology goes. It’s almost like you’re talking to a canvas that will update and change. People are finding it helpful for a lot of things. My favorite one is—it’s hard to admit that I had no idea how hearts work. The last biology course I took was in high school. I just asked it, “How does the heart work?” and it instantly gave me a beautiful interactive diagram of where blood flows and how it goes through. I’m really, really bullish on this for learning in particular. You’ve described useful applications in finance, health, and learning, and ChatGPT has 1.2 billion users. If people are getting so much value, why is public polling on AI so negative? The reality with AI is it is going to change the nature of how work gets done. For a lot of people, that is something that can feel scary at times, and we’ve all felt that. But I remain confident that when people actually use the product and they use AI, it very quickly changes how they perceive it. We’re at 1.2 billion, but there are still a lot of people who haven’t used it. The more people use it, get familiar with it, how it can actually help you in your life, it’s going to feel a lot less scary. Big Technology is a reader-supported publication. To receive new posts and support our work, please consider becoming a paid subscriber. Thanks!! Subscribe

Nov 3 • 10:00 AM EST • Technology • bigtechnology.com

Losing the Endangerment Finding: Air-Quality and Health Impacts of Recent and Proposed Regulatory Rollbacks

The repeal of standards for light-duty vehicles and power plants will increase air pollution that contributes to death and disease, adding to the already substantial forgone climate-related benefits of these regulations by about $780 billion.

Nov 3 • 7:00 AM EST • Health • resources.org

New York health officials report 1st measles death in 3 decades

The New York State Department of Health and Lewis County Public Health yesterday reported the first known measles-associated death in New York State in more than 30 years. State health officials state: “The Department has offered resources to Lewis County to assist with community outreach and support local vaccination efforts – both in response to this c…

Nov 3 • 6:41 AM EST • Health • outbreaknewstoday.substack.com

Trump Effort to Prove Rampant Noncitizen Voting Leads to Few Charges So Far

Just 236 people have been charged with voting-fraud-related offenses by the Trump administration, despite its unsubstantiated claims that fraud is widespread.

Nov 3 • 5:03 AM EST • Politics • nytimes.com

Independent Talent to Rep Outernet London for Creative Commercial Strategy (EXCLUSIVE)

Independent Talent Group have been appointed creative commercial agency for immersive U.K. venue Outernet London. The partnership will unite Independent’s substantial client list – which includes arti...

Nov 3 • 5:00 AM EST • Entertainment • yahoo.com

Grand Jury Rejects Trump Administration’s Effort to Charge Individual With Voter Fraud

The rejection demonstrates the department’s harried push to prove President Trump’s unsubstantiated claims of rampant voter fraud.

Nov 2 • 5:50 PM EST • Politics • nytimes.com

Kyrie Irving trade proposals: 3 best fits for Mavericks guard

Kyrie Irving could draw substantial interest at the NBA trade deadline and we broke down the best fits and ideal trade packages.

Nov 2 • 4:31 PM EST • Sports • sports.yahoo.com

SGMC Health Welcomes Kelsey Bree Harper, MD, OBGYN to Medical Staff

SGMC Health is pleased to welcome Kelsey Bree Harper, MD, an obstetrician-gynecologist to its medical staff.

Nov 2 • 3:08 PM EST • Health • sgmc.org

River Valley 911 center to receive $8 million federal grant

Wes Milam said news of a federal grant that will substantially help fund a new 911 call center in Sebastian County is “a huge relief,” and will eventually help police,...

Nov 2 • 2:21 PM EST • Business • talkbusiness.net

Shots fired into South Side Bethlehem business, police say

A business was hit by gunfire Monday morning in South Side Bethlehem.

Nov 2 • 1:36 PM EST • Business • mcall.com

Communities That Care Coalition unveils 2026 Student Health Survey data

The 2026 Student Health Survey shows improved youth mental health and lower substance use in Franklin County and North Quabbin.

Nov 2 • 1:25 PM EST • Health • recorder.com

Lobster industry caught in Maine’s political headwinds before US midterms

Nov 2 • 10:54 AM EST • Politics • aljazeera.com

Brisbane 2032: the sports being forced to modernise in bid to stay in Olympic race

Microchips, ninja obstacle courses and other ‘modern’ tweaks are being made by sports vying for a coveted spot on the Olympic program in Australia

Nov 2 • 9:00 AM EST • Sports • theguardian.com

Small businesses face these common hurdles

Understanding the potential obstacles that small businesses face can help guide aspiring entrepreneurs.

Nov 2 • 3:26 AM EST • Business • bostonherald.com

Real-World Weight Journeys: Exploring Health Experiences to Improve Care

(Feature Impact) A number on a scale tells only part of the story. Living well is also about having energy, feeling your best and enjoying a good quality of life. Yet each person’s path is different, and lifestyle changes, medicines and other approaches to managing weight can affect health in different ways. TNCMS.AdManager.render({region: 'fixed-big-ad-top-asset', slot: 1, fold: "above"}); No two weight-management journeys look the same. Some people are taking their first steps toward healthier habits. Others are balancing health conditions, caring for family members, coping with stress or exploring new treatment options. Along the way, they may find support that helps them succeed or encounter obstacles that make progress more difficult.These stories provide valuable insights into what it takes to improve health in everyday life.That’s the idea behind the American Heart Association’s Healthy Living BEYOND Weight Study. By learning directly from adults across the country, researchers aim to better understand the challenges, motivations and factors that shape weight and health outcomes over time. The goal is to generate insights that can help improve support, inform care and empower more people to live healthier lives.What Factors Influence WeightNearly 1 in 3 U.S. adults are overweight and 2 in 5 are obese, according to the National Institutes of Health. Weight is shaped by many factors, including:Genetics and hormonesAccess to healthy food, safe places to exercise and healthcareChronic stress and mental healthMedications and metabolismCommunity conditions, as where you live can influence your ability to live a healthy lifeHow Joining a Study Can Make a Difference Led by the American Heart Association, the Healthy Living BEYOND Weight Study is open to U.S. adults with a BMI of 25 or higher, including those who have tried lifestyle changes, weight-management medicines or weight-loss surgery. By sharing information about their health and daily lives, participants can help researchers better understand how to improve care.Interest in newer weight-loss medicines, such as GLP-1s, has grown rapidly. While these treatments are helping many people, researchers are still learning about their long-term effects and how they fit into everyday life. People who currently use or previously used a GLP-1 may be eligible to participate and help generate insights that could improve care for others.Reasons to Join This StudyBy joining this study, participants can help researchers better understand the long-term impact of treatments, identify what helps people succeed and uncover the challenges they face along the way. The information they share can help fill important gaps in research, shape better and more compassionate care and guide future health recommendations.According to the Pew Research Center, 31% of U.S. adults report they’re online “almost constantly.” The study is conducted entirely online, making participation convenient and easy. It can be completed from home on a schedule that works best for each participant.Consider these reasons to participate:Your story matters. By participating, you may help build knowledge that can improve care, guide health recommendations and help people live healthier lives.It’s easy. The study is conducted entirely online, making it simple to join and stay involved at your own pace.It’s safe and respectful. All data is collected with your informed consent, protected by privacy safeguards and handled according to rigorous ethical and scientific standards.You won’t be alone. Millions of people are navigating weight and health challenges. By sharing your journey, you can help researchers better understand what works, what support is needed and how to shape better and more compassionate care for others.Learn more and consider signing up at Heart.org/GoBeyond.Photo courtesy of Shutterstock

Nov 2 • 1:00 AM EST • Health • derbyinformer.com

BMP hospital ruling raises wider questions about speaking up in health care

By William Crooks Quebec’s labour tribunal has ordered safer work organization at Cowansville’s Brome-Missisquoi-Perkins Hospital after finding inadequate control of psychosocial risks and insufficient protection of meal and rest breaks. Separately, research involving Université de Sherbrooke researchers found fear of reprisal among more than half of part…

Nov 1 • 6:01 PM EST • Health • publisherpt.substack.com

Why 2026 Is a Health Care Election

_Ypsilanti, Michigan_THE MIDTERM ELECTION IS ABOUT a lot of things: gas prices and groceries, the spread of corruption, and the future of democracy. And yet, as much as any single issue, it’s about health care. You can tell by listening to all the Democrats talking about high deductibles, drug costs, and insurance companies as they campaign around the country. Or you can tell by reading all the public-opinion surveys in which voters consistently rank health care as one of their top concerns. But if you really want to know why this is a health care election, your best source isn’t the politicians or the pollsters. It’s the people on the front lines. One of them is Raymond Rion, a family medicine physician and executive director of Packard Health, a small network of clinics spanning Ann Arbor and Ypsilanti on the western outskirts of the Detroit metro area. Packard is what’s known as a Federally Qualified Health Center, where anybody can get care regardless of income or insurance status. And like similar safety-net providers all over America, for the past decade it has benefited directly from the Affordable Care Act. “We almost went bankrupt in 2011,” Rion told me in a conversation last week, recalling how in the old days staff at Packard would work the phones furiously to get supplies and find specialists who would take referrals. Now many more patients have either Medicaid or private coverage they’ve purchased through HealthCare.gov, the online marketplace that the law created, so that the proportion of uninsured patients has fallen from around one in three to one in ten. It’s a lot easier to find referrals for these insured patients, though thanks to the infusion of paying customers Packard can do much more on its own. In particular, Rion said, the organization has opened two new branches, started a pharmacy, begun offering prenatal services, and vastly expanded behavioral health care by bringing on a half-dozen new doctors, nurses, and case workers. Now a retrenchment is underway. Coverage options on the HealthCare.gov marketplace got more expensive because Donald Trump and the Republicans refused to renew temporary subsidies that had been reducing the price of insurance. On top of that, the first cuts to Medicaid as part of last year’s “One Big Beautiful Bill” are starting to take effect. Rion told me Packard has already laid off a provider in anticipation of less revenue next year.1 Patient volume is down, he went on to explain, in part because uninsured patients sometimes avoid care altogether out of fear a single visit will lead to more treatments with more bills. And postponing care in that way can have serious medical consequences, as his colleague Ron Romero told me. “So you have somebody with diabetes, their chronic condition isn’t getting cared for,” said Romero, who like Rion is a family physician. “Their sugars rise, and they end up having other medical problems. Their kidneys start to get damaged. They start to have eye damage. They increase risk for heart attacks and strokes. . . . They end up in the emergency room.” And things are likely to get worse. Partly that’s because next year most of the remaining Medicaid cuts will take full effect, throwing more people off coverage. And partly it’s because forces that have nothing to do with Trump or Republican actions are making medical care more expensive for everyone, including those with employer insurance and Medicare. That will lead to still more people delaying or skipping care, ending up in the emergency rooms, and putting yet more cost pressure on providers. Rion wasn’t taking a position on the election or political parties, he made clear. He was just describing the reality he sees around him: “The whole system is being pressured. Nobody is immune to this stuff.” He’s right. And here’s the thing: This has all happened before. We know happens next.

Nov 1 • 10:06 AM EST • Health • thebulwark.com

Business Weekly Agenda for November 1

Events for the Greater Berks business community.

Nov 1 • 4:45 AM EST • Business • readingeagle.com

Science Spooktacular Returns to Elkhart County 4-H Fairgrounds for Halloween

WSBT CBS 22 provides news, sports, entertainment and public interest programs to the South Bend, Indiana area including Mishawaka, Notre Dame, Granger, Osceola, Elkhart, Jimtown, Dunlap, New Carlisle, Goshen, Middlebury, Bristol, New Paris, Nappanee, Howe, Lagrange, Topeka, Bourbon, Milford, Syracuse, North Webster, Warsaw, Bremen, Plymouth, Walkerton, Argos, Tippecanoe, Culver, Grovertown, Delong, Rochester, Akron, Winamac, North Judson, LaPorte, North Liberty, Wakarusa, Lapaz, Millersburg, Knox, and Michigan City, Indiana – and these areas of Michigan: St. Joseph, Benton Harbor, Buchanan, Niles, Three Oaks, New Buffalo, Harbert, Bridgeman, Stevensville, Watervliet, Berrien Springs, Dowagiac, Marcellus, Cassopolis, Decatur, Vandalia, Constantine, White Pigeon, Galien and Edwardsburg.

Oct 31 • 5:31 PM EDT • Science • wsbt.com

Scaring Up Customers for Halloween Streaming

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) Way back in 2022, I did a deep dive into each streamer’s horror offerings, looking at the top horror film and TV shows, and which streamers had the best library titles and best Halloween landing pages. If you’d like to check out those articles... Way back in 2022, I ranked all the streamers’ Halloween landing pages. I updated my thoughts in 2023... ...and 2024. After taking last year off, I’m back at it again this year. My theory—then and now—is that Halloween landing pages provide a subtle but surprisingly valuable insight into how the streamers position themselves, and what they do well and what they don’t. They show who relies on libraries, whose libraries across TV and film have the most value, who understands how customers want to access those libraries, and, being blunt, which product teams actually put the time in to make a quality holiday user experience. Plus, three “horror” TV shows had big debuts this month! So today, I’ll answer the questions... What are the all-time biggest horror shows and films on streaming? What streamer has the best library? What streamer has the best landing page? And what does this say about the streaming wars today? But first, let’s look at three big new horror shows on streaming... Subscribe Horror TV Has Dominated October So Far In a fun twist this month, three different streamers released three different horror TV shows. Many scary stories come out every October, but the twist is that all three did well: Two of the shows got over 20 million hours, which is just good. You can see that Below is helping Netflix start October/Q4 off well: And that Carrie is a top seven show for Amazon through two weeks: But here’s the crazier note: even though it doesn’t look huge, Crystal Lake is Peacock’s biggest debut yet: Let’s discuss the streaming elephant in the room: two of these shows are based off classic horror IP: Jason and Carrie. So once again, IP works, in theaters and on streaming. It just does. Oddly enough, horror IP doesn’t draw a tenth of the ire that other IP does, even though, arguably, horror films are the original franchise films, starting in the 1930s and continuing on through the slasher film 80s. So horror TV shows are off to a great start. While I’ve written before that horror films do NOT over-perform on streaming, TV shows are a different story. The Top Horror Films and TV Shows on Streaming All Time To start, here are the top first seasons for all streaming TV shows since 2020 (the start of the Streaming Ratings Era): First take: yep, that’s some power laws at work right there. The biggest TV show hits aren’t just bigger than other hit shows, they’re orders of magnitude bigger. Wednesday dwarfs The Last of Us (a big hit!) and is ten times bigger than the next six most popular horror shows. Wow! So yes, horror or horror-adjacent shows can do as well as the top shows on streaming. Wednesday is proof of this. (Though, even Wednesday is more horror-adjacent than proper horror.) Also, note that Below, Carrie and _Crystal Lake_could/should keep moving up the charts. That said, there is some weakness in these numbers. Only eighteen horror first seasons made the charts, which is low. For context, 541 season ones have made the Nielsen originals charts since 2020. Eighteen out of 541 isn’t great! Plus, again, the IP issue. Wednesday and The Last of Us came from popular IP, and It: Welcome to Derry and Goosebumps are spinoffs. Next up, every horror show from season two on: The bad news here? Besides one iconic example, horror shows don’t last long i.e. generate very many seasons. While many straight-to-streaming horror shows were limited series, many weren’t and only four horror shows got to a second season or beyond. That’s a bad hit rate. And yeah, only one horror show made it to a fifth season! This genre is just not elite (on streaming). Okay, on to the top horror films all time (er, since 2020): We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… ...What streamers have the most horror films... ...And how FASTs have embraced horror films... ...How many elite horror films are on linear TV or aren’t on TV at all… ...How streamers make it very, very hard to find horror films… …And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.

Oct 30 • 5:58 PM EDT • Entertainment • entertainment.substack.com

Wabanaki Public Health cuts nearly 20% of workforce amid multi-million-dollar detox deficit

Leadership described the staff reductions as an agonizing necessity for an organization dedicated to treating substance use disorders across Maine communities.

Oct 30 • 5:30 PM EDT • Health • wabi.tv

2026-2027 Audree V. Fowler Fellows in Protein Science

Graduate students Lenka Milojević (Zhou group), Akshaya Narayanasamy (Lindert group), Sarah Singleton (Conway group), and Janet Zhong (Feigon group) have been selected as 2026–27 Fowler Fellows and shared their research at a special event on Oct. 13, 2026. 2026-27 Fowler Fellows – Sarah Singleton, Lenka Milojević, Janet Zhong, and Akshaya Narayanasamy. Akshaya Narayanasamy and Prof. Steffen Lindert. Sarah Singleton and Prof. Stuart Conway. Janet Zhong and Prof. Juli Feigon. About the 2026-27 Audree Fowler Fellows in Protein Science Lenka Milojević is a fifth-year Biophysics Ph.D. candidate in the lab of Professor Z. Hong Zhou at UCLA. As an undergraduate at Maastricht University, she studied the structural basis of Mycobacterium tuberculosis virulence and amyloid-β fibril nucleation in the lab of Professor Peter Peters. She completed her bachelor’s thesis research at UCLA in the lab of Professor David Eisenberg, focusing on amyloid disaggregation, before beginning her doctoral studies. In the Zhou lab, Lenka uses cryo-electron tomography to visualize and characterize membrane-associated protein assemblies across a range of viral and cellular systems. Akshaya Narayanasamy is a fifth-year Ph.D. student in the Department of Chemistry and Biochemistry at UCLA, mentored by Professor Steffen Lindert. She earned her B.S.-M.S. in Chemistry from the Indian Institute of Science Education and Research, Thiruvananthapuram, where she worked in Professor Mahesh Hariharan’s lab investigating how single-atom substitutions influence crystal packing and charge transport behavior. She received her M.S. in Physical Chemistry from The Ohio State University before moving with the Lindert lab to UCLA. At UCLA, Akshaya develops integrative modeling methods that combine deep learning and Rosetta with experimental data, such as ion mobility mass spectrometry and cryo-EM, to improve protein structure prediction. Her current work focuses on developing an experimentally guided diffusion model and designing de novo protein binders with potential antibacterial activity. Ultimately, she aims to bridge AI-based structure prediction and experimental data to make computational protein models more reliable for drug discovery and therapeutic design. Sarah Singleton is a 4th year BMSB student, working in Professor Stuart Conway’s lab. She earned her B.S. in Biochemistry at Simmon University (Fenway, MA). Her research is centered on drugging the previously undruggable class of proteins—transcription factors. Zinc finger (ZF)-containing transcription factor proteins typically contain multiple ZF motifs, but little is known about the principles that govern the recognition of multi-ZF arrays by immunomodulatory imide drugs (IMiDs). In a multi-ZF array that contains several potentially targetable ZFs, which will be accessible and why? How does the surrounding protein architecture inform IMiD recognition? Sarah’s research aims to utilize her findings on the fundamental principles of ZF recognition to design IMiD therapeutics for transcription factors involved in health and disease. Janet Zhong is a fourth-year BMSB student, working in Professor Juli Feigon’s laboratory. She received her BSc and MRes from Imperial College London. At UCLA, Janet combines cryo-electron microscopy (cryo-EM) and biochemical approaches to investigate how proteins and RNAs assemble into ribonucleoprotein structures. Her research focuses on telomerase, the enzyme that maintains chromosome ends, with interests in its structure, assembly, and mechanisms. She has also worked on capturing the cryo-EM structure of a small bacterial non-coding RNA called raiA motif RNA. About Dr. Audree Fowler A strong supporter of the basic sciences and medicine at UCLA, alumna Dr. Audree Fowler (B.S. ’56 chemistry, Ph.D. ’63 biochemistry) established the Audree V. Fowler Fellows in Protein Science in 2008. Fowler was Director UCLA Protein Microsequencing Facility from 1984-1999 and is a Researcher Emeritus of the UCLA Department of Biological Chemistry. She is one of the first four women to receive a Ph.D. from the UCLA Department of Chemistry & Biochemistry. In 2018, the women were awarded the department’s 2018 Alumni Legacy Awards in recognition of their achievements in life, and generous support and service to UCLA. “The sciences gave me a great life. Now I want to help others have access to the same opportunities I enjoyed,” Fowler explained when she established the Fowler Fellowships endowment. Applications for the fellowships are solicited from graduate students in the Molecular Biology Interdepartmental (MBI) Ph.D. Program, Biological Chemistry, and Chemistry & Biochemistry Departments. In addition to presenting their research at a special seminar, the recipients each receive a $5,000 award. Previous Fowler Fellows from the UCLA Department of Chemistry & Biochemistry 2025-26 – Nikki Cheung (Clubb Group), Jonathan Jih (Zhou Group), Eileen Olivares (Loo Group), and Lily Taylor (Rodriguez Group) 2024-25 – Andrew Goring (Clubb lab), Eric Pang (S. Clarke and Rodriguez labs), and Miranda Villanueva (Backus lab) 2023-24 – Alexandra Turmon (Backus lab), Cindy Wang (S. Clarke and C. Clarke labs) 2022-23 – Cody Gillman (Gonen lab), Declan Evans (Houk lab), Troy Lowe (S. Clarke lab), Ashley Julio (Backus lab), and Alex Stevens (Hong Zhou lab) 2021-22 – Weixian Deng (Wohlschlegel/Plath labs), Yi Xiao “Sean” Jiang (Eisenberg lab), Maria Flores (Rodriguez lab), Carter Lantz (Loo lab), and Logan Richards (Rodriguez lab). 2020-21 – Janine Fu (Loo lab), Calina Glynn (Rodriguez lab), and Jiahui Lu (Eisenberg lab) 2019-20 – David Boyer (Eisenberg lab), Orlando Martinez (Clubb lab) and John Muroski (Loo lab) 2018-19 – Scott McConnell (Clubb lab), Kevin Murray (Eisenberg lab), Rebeccah Warmack (S. Clarke lab) 2017-18 – Michael Hughes (Eisenberg lab), Yuxi Liu (Yeates lab), Kanishk Jain (S. Clarke lab) 2016-17 – Brendan Amer (Clubb Lab) and Jeff Vinokur (Bowie Lab) 2015-16 – Henry Chan (Feigon lab), Smriti Sangwan (Eisenberg lab), Nicholas Woodall (Bowie lab) 2014-15 – Dan McNamara (Yeates lab) 2013-14 – Alex Jacobitz (Clubb lab), Alexander Patananan (S. Clarke lab), Carly Ferguson (Loo lab) 2012-13 – Letian Xie (C. Clarke lab), Anni Zhao (Eisenberg lab) 2011-12 – Timothy Anderson (Clubb lab), Soohong Kim (Weiss lab) 2010-11 – Zeynep Durer (Reiser lab), Cecilia Zurita-Lopez (S. Clarke lab) 2009-10 – Luki Goldschmidt (Eisenberg lab), Kristofer Webb (S. Clarke lab), Sheng Yin (Loo lab) 2008-09 – Nathan Joh (Bowie lab), Neil King (Yeates lab) Photos courtesy of Helen Houldsworth, the Molecular Biology Institute.

Oct 30 • 3:01 PM EDT • Science • chemistry.ucla.edu

Science Begins With Wonder and Sometimes With a Salamander.

The Bar Harbor Story is generously sponsored by the Don & Beth Straus Center at Birch Bay Village. BAR HARBOR—The children had come to see the axolotls, those odd little salamanders with pink frills around their heads and the remarkable ability to grow back what they lose. But also there were stickers. There were crafts. There was the kind of excitement that makes a roomful of kindergarteners forget, for a little while, that sitting still is ever a requirement. And then there were the animals themselves, alive in their clear cases at the MDI Biological Laboratory, where 12 children from Pemetic Elementary School got to meet the creatures they had been learning about in class. “Do you love them?” their teacher, Carol Null, asked. The answer came back in a chorus. “I do!” “I do!” “I do too,” Null said, smiling. “I love them even more now.” That was the thing about a day at the lab. Science was no longer a picture in a book, or a word on a classroom wall. It had a face, a tail, and a set of extraordinary powers. And for a child, sometimes that is where wonder begins. Sometimes learning about science is about stickers. Sometimes it’s about bright pink feathers and getting super excited about that glow in the dark. Sometimes learning about science is joy—pure and simple joy. That’s how it was October 28 at the MDI Bio Lab as Miss Hannah (known in the lab as Dr. Hannah Lust, director of STEM, undergraduate and graduate Training), other scientists, graduate students, and MDI Bio Lab staff, hosted 12 students from Carol Null’s Pemetic Elementary School’s kindergarten class. The 2.5-hour program created by Dr. Lust focused on axolotls, a species of mole salamanders, a superhero in the animal world: a superhero with some scientific-study worthy superpowers. One of those superpowers come from the axolotls’ ability to regenerate body parts, including entire limbs. But also, they’re cute. This fall, before coming to the internationally renowned lab nestled in Salsbury Cove, Null has been integrating axolotls into her class. They’ve been part of the kids’ vocabulary and their storytelling. They’ve been part of science. They’ve been part of the children’s learning about facts vs opinions. The Pemetic Elementary kindergarten students learn about invasive species and the impact on the ecology and one student related it to their dad, who lobsters, and his worries about green craps, an invasive species in Maine. “Are they bigger or smaller than you thought they’d be?” the children are asked after the scientists show them multiple see-through cases of axolotls, lined up on a table that they’re told not to jiggle. “Bigger!” “I think they’re bigger.” “Smaller!” The bio lab opening its doors to the collaborations and to students and families is a norm, but this is the first program of this kind. It’s meant to encourage kindergarten students about axolotls. But when the students come to the bio lab something else happens too—something beyond Null’s child-focused teaching—the students see science—and the regenerating creatures in real life. They do crafts. They speak with them. They meet people who know all about them: scientists and educators who talk to the kids like they’re equals. That’s a superhero power, too. Null speaks about meeting the kids where they’re at in her classroom, letting their interest and hearts lead her in their learning. That requires recognition of interests, of individuality, of empathy. Some would argue that’s a super power, too, but it’s also in those 12 students as they listen to the storybook, encounter those live axolotls, and hear about how axolotls might help advance society’s understanding of human health. As Eddie Seckeler (comparative animal models, CORE facility manager), carefully puts the axolotls on a cart and rolls them away, some of the children stop what they’re doing to watch. “Bye axolotls.” “Bye!” “Bye!” The axolotls are not just images in a book, Hello, I’m an axolotl by Hayley and John Rocco; they are real and cool. MDI Biological Laboratory scientists Dr. Prayag Murawala and Dr. James Godwin who both feature in the Roccos’ book. The kindergarteners get to meet them in real life, off the page, in the world, doing science. They learn from them, laugh with them. “The visit is about more than meeting an unusual animal. By introducing children to scientists working in their own community, the experience helps make science tangible and accessible. Students can see that science is not just something they read about in books or learn about at school. It is something real people do every day by asking questions, making observations and working to understand how the world works,” explains MDI Biological Laboratory Director of Communications Rebecca Woods. While the students make axolotl-related crafts around tables, graduate students and staff help out. Ryan holds up his construction paper setting and axolotl to show Omar Maged, a graduate student. “Do you like it?” Ryan asks, eyes wide, turning from his axolotl to look up at Omar. Omar studies the construction paper for a moment, smiles and says definitively, each word important. “It is beautiful.” Null says that she’s so thankful for all the “amazing” community partners that her school and her students get to interact with as they learn and grow and live, but emphasized how the MDI Bio Lab goes out of its way to create something meaningful, something that allows her young students to build their own agency, to know that they can be impactful in their community, to show them how how things they learn about in text is connected to themselves and their community. Woods explains, “Axolotls have an extraordinary ability to regenerate, or regrow, certain body parts, including limbs. Scientists study these animals to understand how regeneration works and what their biology might teach us about tissue repair and healing in humans.” The children enter the space for “a memorable introduction to a big scientific question,” Woods said. “How can some animals regrow body parts? The encounter encourages children to look closely, wonder about what they see and begin to understand how scientists use observations and experiments to investigate questions.” “For the students, the visit is an opportunity to explore a fascinating animal and meet scientists in their own community,” Woods explains. “For MDI Biological Laboratory, it is a chance to share the excitement of research, nurture curiosity, and help young learners discover that science begins with asking questions.“ At the beginning of the school year, Pemetic kindergarteners didn’t know what the axolotl was—at least not exactly—now they know all about the axolotl’s life cycle. “It’s different than a butterfly,” one student told Mrs. Null. It is. The change and knowledge might seem small**,** but it offers a glimpse of what happens when a subject moves beyond the pages of a book and into a child’s world. The children have been learning about butterflies at the Charlotte Rhoades Park and Butterfly Garden. At both the garden and the MDI Bio Lab, the children see the animals, meet the scientists who study them and at the lab encounter a question that researchers are still working to answer: how can some creatures regenerate body parts, and what might that teach us about healing in humans? They leave with gift bags, paper-plate salamanders, new things to wonder about and a connection between the science they learn in school and the work happening in their own community. The axolotls may be remarkable for their ability to grow back what they have lost. For these young students, the day offers something different: a chance to discover how much there is to ask, observe, and imagine. When Null’s students had time to use chalk and draw whatever they want, in the beginning of the year, they drew rainbows. Now? They’re using that chalk and choosing to draw axolotls instead. About MDI Bio Laboratory For more than 125 years, MDI Bio Lab has been a center for training and research in comparative biology. In the last two decades its biomedical research has focused on aging, regeneration, and environmental toxins. The Laboratory houses 11 research groups staffed by an international team of world-class scientists and graduate students. It also leads a statewide network of colleges, universities and research institutions that collaborate to provide training, research experiences and financial support to help young Mainers play a bigger role in today’s biomedical revolution. Located on Maine’s rugged coast, the Laboratory’s 100+ acre campus houses research facilities, cottages and dorms that house visiting scientists and students. It is also home to MDI Bioscience, a subsidiary working to design innovative techniques to speed the drug discovery process. The Bar Harbor Story is generously sponsored by Rick Osann Art. LINKS TO LEARN MORE NIH INBRE MDI BIOLOGICAL LABORATORY Pemetic Elementary School Hello, I’m an Axolotl Photos: Carrie Jones/Bar Harbor Story HELP SUPPORT THE BAR HARBOR STORY When we started The Bar Harbor Story, we didn’t know if anyone would read it. But you showed up. You shared. You sent tips. Now—over 400,000 views every month later—it’s clear: people here care about their community and each other. We’ve kept everything free because news should never be out of reach, but every one of our stories takes time to write, and your support keeps The Bar Harbor Story going. If you value our work, please consider a paid subscription, a founding membership, or a sponsorship. It truly helps us cover one more meeting, tell one more story, shine one more light. Even $5 a month makes a difference. Click here to become a one-time supporter now. Thank you so much for being here. Founding member information can be found here. Have questions about sponsorships? Just send Shaun an email at sfarrar86@gmail.com, he’d love to hear from you. Subscribe Share Bar Harbor Story Share Leave a comment

Oct 30 • 9:07 AM EDT • Science • barharborstory.substack.com

Zelda 40th Anniversary Switch 2 restock update: the Nintendo Store remains your best bet

🎮 The Zelda 40th anniversary Switch 2 was released on October 29 and flashed in and out of stock at the Nintendo Store 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert as soon as stock appears 👀 Walmart was our top pick to have a restock, but a supply chain delay has pushed the date back ⌚ In-store midnight launches are being held at GameStop, Best Buy, and Nintendo New York/San Francisco Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 The Legend of Zelda 40th Anniversary Switch 2 launched yesterday, and it was the Nintendo Store that held the most restocks. The console flashed in and out of stock repeatedly throughout the day as limited units were sold and quickly snapped up. 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe Many were met with error messages, “sold out” signs, or “couldn’t add the required amount” to their baskets. However, with a little persistence and luck, others were more successful. As it stands, it’s the best place to try to get the Zelda Switch 2, even if the experience can be a little frustrating. We’re expecting a similar situation today as our tracker continues to receive restock alerts. However, we’re reluctant to share them all as many have been false flags, but we immediately notified The Shortcut followers once the first restock went live. [ The Shortcut@theshortcut Zelda Switch 2 is back in stock at the Nintendo Store: nintendo.com Nintendo Switch™ 2 – The Legend of Zelda™ – 40th Anniversary Edition - Nintendo Official Site 4:18 PM · Oct 29, 2026 · 2.09K Views 2 Replies · 2 Likes ](https://x.com/theshortcut/status/2115840807773299128?a=b6yhtCFmoswv5lWWvEs&s=20) Amazon was the only other retailer to hold an online restock, though it sold out almost instantly. No more restocks took place, and sadly, the major Walmart restock of the Zelda Switch 2, which we were confident would take place, did not happen because of a supply chain issue. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2115824408938111299?a=quc3qYd6I_Qe5wag2lU&s=20) 🚨 Zelda Switch 2 console at Amazon right now amazon.com/dp/B0HJ6F8L6V?… amazon.com Nintendo Switch™ 2 –The Legend of Zelda™ – 40th Anniversary Edition 3:13 PM · Oct 29, 2026 · 76.7K Views 32 Replies · 4 Reposts · 57 Likes The console will now be available to order online at Walmart on November 6, with Target also offering the same date. Some lucky shoppers could also get the Zelda Switch 2 in-store, with The Shortcut readers sharing their personal accounts of getting the console at Walmart and helping each other out. If you’re willing to travel to your local store, Best Buy and Nintendo are holding in-store events on November 5 (though you’ll need a Warp Pipe Pass for Nintendo’s event). GameStop is also letting customers pre-order in-store.. We’ll still be tracking every retailer with our exclusive Zelda 40th anniversary Switch 2 restock tracker, which provides up-to-the-second information when the Zelda Switch 2 is in stock. If the console appears – which it might – our followers will still be the first to know. Up next: PS5 Pro restock: it’s available again, but you’re paying more than you should Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.

Oct 30 • 6:45 AM EDT • Technology • theshortcut.com

The politics of war

Israel went to the polls last Tuesday and it is the turn of the United States next Tuesday. The differences in the two elections are self-evident. Compared with the US, which has favourable geography and does everything at scale, Israel is tiny and part of an unstable region. For its elections, it has adopted an almost pure form of proportional representation based on lists. This encourages multiple parties and can make it almost impossible to form a government, as we can now see. The US system is complex in its own way but discourages third parties. Yet for all the differences in size, geography, and political systems, the fates of the two countries are closely connected. Israel has come to depend on the US to sustain its military strength, and over the past few tumultuous years that dependence has created resentment in the United States. The Biden administration was punished for appearing to give Netanyahu a blank check after the Hamas attacks of 7 October 2023, and not holding Israel back as it employed ruthless tactics in Gaza. Because of the treatment of Palestinians, American views of Israel have grown progressively more negative over the past few years. Only a third now support the Israeli government. While on the left, this is largely because of how Israeli forces have operated in Gaza and, more recently, how the settler movement has behaved in the West Bank, for the American right the issue has been about how Benjamin Netanyahu persuaded Donald Trump to forget his wariness about more Middle Eastern wars and agree to a joint attack on Iran, which has gone badly wrong. The Palestine question was not a big issue for the two large Jewish blocs in last Tuesday’s election. Both supported a tough response to Hamas after October 2023 and neither accepts a two-state solution. It was, however, the threat posed by the ethno-nationalist policies of Itamar Ben-Gvir and Bezalel Smotrich, the two extreme members of Netanyahu’s coalition, and their tolerance, even encouragement, of settler violence, that brought out the Arab voters. (In principle this should strengthen their position though to turn into real power would require the ‘Change Bloc’ overcoming their opposition to involving Arab parties. The alternatives are a National Unity government, defection from the Change Bloc to Netanyahu, or deadlock and another round of elections in the new year.) There was also broad support for the war against Iran among the Jewish parties. The difficulty here is that the objectives behind the war have yet to be met, and that continuing with military operations depends on the United States. In this way the two elections have come together at a crucial moment. If Netanyahu hoped that a victory over Iran would help him retain his majority, cementing his legacy as an Israeli war leader, it did not work out that way. Trump also expected a great victory about which he could boast. He promised at most the end of a hateful and aggressive regime, with a record of hostility to both the United States and Israel, or at least the elimination of Iran’s military capabilities and the end of its nuclear programme. Eight months on, there is not much to boast about; vital objectives remain elusive: the Iranian regime is even more hardline than before; the international economy is barely coping with the closure of the Strait of Hormuz; and Saudi Arabia is struggling with an unwanted conflict with the Yemeni Houthis. For all these reasons, the Iran War has been a dark cloud hanging over both elections. Yet the issue has been approached in different ways. Netanyahu sought to push the issue before the election while Trump has been more cautious. Trump’s essential claim is that there is nothing to worry about and he’s still working out what final steps need to be taken to provide a definitive conclusion to the conflict. Netanyahu’s final pitch was that there was lots to worry about. He focused on Israel’s dire security situation, with the Iran War unfinished and the prospect of imminent economic isolation because of international sanctions. For him it is imperative to defeat Iran decisively, and without delay. Why this different response to the same war? Part of the answer lies in how public opinion in the two countries responded to the war. In this post, I show how this came about. We await the outcome of the US midterms but know the result, at least in terms of the share of the vote if not yet the shape of the new government, of the Israeli election. With the elections out of the way Netanyahu is pressing for another round in the war. Trump is less sure. I conclude with thoughts on the importance of how he decides.

Oct 30 • 5:22 AM EDT • Politics • samf.substack.com

Boston sports political donations: How team owners gave ahead of midterms

A Globe analysis found substantial political giving, in particular, by the owners of the Patriots and Bruins and their families, both at the state and national levels.

Oct 30 • 3:00 AM EDT • Politics • bostonglobe.com

Japanese Safety Science Symposium Brings Everyday Health Risks to the Public

The Japanese Environmental Mutagen and Genome Society opened its 2025 symposium to the public, presenting research on pharmaceutical and food safety, PFAS, radioactive substances in food, indoor formaldehyde, and colibactin.

Oct 30 • 12:39 AM EDT • Science • bioengineer.org

New substance use and mental health treatment center opens in Springfield

A new substance use and mental health treatment center has opened in Springfield, expanding access to recovery services for residents across Hampden County.

Oct 29 • 7:57 PM EDT • Health • wwlp.com

Fall 2026 Credo Awards announced

Established in 2008, the Credo Award recognizes individuals who consistently demonstrate exceptional credo behavior by making those they serve their highest priority, having a sense of ownership, conducting themselves professionally, respecting privacy and confidentiality, communicating effectively, and exhibiting commitment to their colleagues. The Fall 2026 Credo Award winners are: Shannon Blaisdell, DNP, MSN, RN, Associate Nursing Officer, Inpatient Obstetrics and IV Team, Vanderbilt University Hospital Sara Hanai, MS, Director, Junior League Family Resource Center, Monroe Carell Jr. Children’s Hospital at Vanderbilt Kelly Harper, Research Program Manager, Neuro-Movement Disorders Division, Department of Neurology The Credo Award recognition is announced quarterly through the Vanderbilt Health Hub. A total of 12 winners will be recognized each year. Each winner is honored with an award video, a profile article in VUMC Voice following the award announcement, and recognition during the biannual Leadership Forum. View the Fall 2026 Credo Award videos. If you are a Vanderbilt Health employee, you can nominate a colleague, leader or team for a Credo Award, C. Wright Pinson Leader Award, or Vanderbilt Health Team Award. Visit the Awards and Nominations SharePoint site to fill out a nomination form. Employees demonstrate credo behaviors when: they make those they serve the highest priority; respect privacy and confidentiality; communicate effectively; conduct themselves professionally; have a sense of ownership; and are committed to their colleagues. Award nominations are accepted year-round. If a nomination is received after the cutoff for an award selection period, the nomination will be considered for the next period.

Oct 29 • 3:59 PM EDT • Health • news.vumc.org

Wolverine lifts PS5, but Xbox struggles despite Gears of War launch

Oct 29 • 10:47 AM EDT • Technology • thegamebusiness.com

Zelda 40th Anniversary Switch 2 restock: Walmart and Target confirm exact release dates

🎮 The Zelda 40th anniversary Switch 2 is out today, October 29, but Walmart and Target are planning online restocks for November 6 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert as soon as stock appears 👀 Walmart was our top pick to have a restock, but a supply chain delay has pushed the date back ⌚ GameStop, Best Buy, and Nintendo are holding in-store midnight launches where units will be available Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 A new update has dashed our hopes of a major Walmart restock of the Zelda Switch 2 console, which we were confident would happen today. However, a new Reddit post (thanks, Wario64) has revealed that Walmart is waiting until at least November 6 to sell the special edition console online. 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe A employee note says: “Due to a supply chain delay, some stores may not receive the Nintendo Switch 2 Zelda 40th Anniversary Edition in time for its planned Oct. 29 release. To allow time to fulfill preorders and reshop inventory as needed, the point-of-sale (POS) block will remain in place through at least Friday, Nov. 6. As inventory arrives, orders will be fulfilled based on preorder priority and available inventory.” The Redditor who posted the news shared that some people were able to get the console from Walmart after 8:00am local time, so there is still hope. Target recently updated its Zelda Switch 2 listing to reveal that it will also start taking orders of on November 6, with in stores orders beginning November 5. Clearly, the supply chain delay is impacting other stores, otherwise we likely would have seen a restock take place today, as we initially predicted. We now know that Walmart and Target will be taking online orders, and that Best Buy and Nintendo are holding in-store events on November 5. GameStop is also letting customers pre-order in-store via their website. Despite the news, we’ll still be tracking every retailer with our restock tracker, which provides up-to-the-second information whether something is in stock. If the Zelda Switch 2 does appear – which it might – our followers will still be one of the first to know. Up next: PS5 Pro restock: it’s available again, but you’re paying more than you should Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.

Oct 29 • 10:35 AM EDT • Technology • theshortcut.com

Dragons Broadcaster Tom Nichols Inducted into Ohio Sports Hall of Fame

The Official Site of Minor League Baseball web site includes features, news, rosters, statistics, schedules, teams, live game radio broadcasts, and video clips.

Oct 29 • 10:18 AM EDT • Sports • milb.com

Man arrested after allegedly stealing from local business, resisting deputies

On Tuesday, Zachary Young, 30, was arrested and charged with breaking and entering, obstructing, fleeing, and trespassing.

Oct 29 • 8:57 AM EDT • Business • wsaz.com

Jeff Probst says “Survivor 51” is a season of ‘formidable women’

The Hostmaster General is packing stats and everything.

Oct 29 • 8:15 AM EDT • Entertainment • yahoo.com

Jeff Probst says ‘Survivor 51’ is a season of ‘formidable women’

Jeff Probst says ‘Survivor 51’ is a season of ‘formidable women,’ and he’s packing stats to prove it.

Oct 29 • 8:15 AM EDT • Entertainment • ew.com

The Israel debate reshaping Jewish American politics

“There are plenty of people who believe, as I do, that Israel has a right to protect itself,” says David to Lauren, both pictured below, over the dinner table. Subscribe “How does starving children protect Israel?” she replies. “I don’t think Israel is intentionally starving children.” “It’s a little bit absurd to be sitting here talking about all of these very specific things,” Lauren says, “as opposed to looking at the totality of him as a candidate, and the 90% of things that you agree with him on.” This is a snapshot from a conversation between a Jewish father and daughter in Michigan ahead of the crucial Senate race. Lauren supports the Democratic candidate, Abdul El-Sayed. Her father is undecided. That is mainly because of El-Sayed’s stance on Israel, one that mirrors a growing wing of the party that has become critical of the US-Israel relationship following the war in Gaza. You’re reading FourSight, a newsletter from Channel 4 News’ expert journalists explaining the complexities of the biggest global stories Could that alienate Jewish American voters who have a strong connection to Israel - and the majority of whom have voted Democratic? A shifting stance on Israel “An ally that takes your money to push you into wars you shouldn’t be fighting is not an ally,” El-Sayed recently told ABC News, referring to the Iran war and how some Americans believe that Israel pushed President Trump into the conflict. Foreign policy has become an economic issue that’s hitting Americans’ pockets, with the soaring cost of petrol and diesel. El-Sayed, pictured below, has opposed military aid for Israel and accused the nation of genocide in Gaza. That led to the pro-Israel lobby group, AIPAC, funding his opponent, Hayley Stevens, to the tune of $30m during the Democratic primary here. “I frequently criticise AIPAC because I think the way that they are pouring dollars into defeating Abdul and others around the country… is really corrosive to American democracy,” Brad Lander says at a canvassing event in Detroit. Lander, a Jewish Democratic congressional candidate in New York, is an ally of Mayor Zohran Mamdani and has come to campaign for El-Sayed. “Democrats and Americans don’t want to keep paying for Netanyahu’s wars,” he says. “They want a reset in the US relationship with Israel.” The 2026 election has clearly been a bruising one for AIPAC; the Wall Street Journal reported that, in an unpublished letter, the group described the cycle as one of the “most challenging environments in recent memory”. Share And significantly, after the midterms, the group will stop direct contributions to candidates through one of its political action committees. Voters’ concerns We followed a group of Jewish canvassers around one suburb in Detroit. They think that among the 130,000 Jewish voters in Michigan, between 20 and 30,000 are undecided. In a swing state where El-Sayed beat his primary rival by just 13,000, that could prove pivotal. We meet one voter, Jen Friedman, pictured below, who has a “Democrats for Rogers” sign, referring to the Republican candidate. The issue of Israel is very important to her because “having a safe haven is crucial”, she tells me. “What I see is one candidate, Mike Rogers, who is associating himself with people who are very proudly American,” says Jen. “Abdul, on the other hand, is associating with people who say they are anti-American.” Friedman raises two issues. Firstly, Hasan Piker, a left-wing streamer who has campaigned alongside El-Sayed and has been criticised for his comments on the US and Israel. [ ](https://channel4news.substack.com/p/who-is-hasan-piker-the-socialist) [ Why Hasan Piker thinks the US needs a socialist Trump ](https://channel4news.substack.com/p/who-is-hasan-piker-the-socialist) Anushka Asthana · Aug 19 [ Read full story ](https://channel4news.substack.com/p/who-is-hasan-piker-the-socialist) The other concern regards an attack on a Michigan synagogue back in March. The FBI said the man was inspired by Hezbollah and had lost relatives in an Israeli airstrike on Lebanon. El-Sayed condemned the antisemitic attack, but also said “hurt people hurt people”. That upset many here, with El-Sayed apologising numerous times for his choice of language. Jews for Abdul As we follow the canvassers, there are still plenty of lawn signs supporting El-Sayed. Elissa Driker, pictured below, runs out of her house wearing a “Jews for Abdul” t-shirt. “I feel like the values that Abdul has align with how I live my Judaism,” she tells me. She says “Abdul is not Hasan Piker, so I don’t conflate them”. I ask why Piker keeps coming up. “It gets weaponised. I don’t know if you watched the debate the other night, but talk about… weaponising fear and weaponising anxiety and all that Islamophobic dog-whistling that was coming towards Abdul.” I also talk to Elissa about how Americans more broadly appear to be questioning the US-Israel relationship and whether American Jews were ready to do that too. “A lot of American Jews are. My experience is absolutely the tide is turning.” For the first time, Gallup found this year that Americans now sympathise more with the Palestinians than the Israelis. In another poll of Jewish American voters, 65% said they were pro-Israel but also critical of Israeli government policies, 52% support cutting or eliminating aid to Israel. Father and daughter Back at the dinner table, I bring up those polls with David Fink. Why does he think Americans sympathise less with Israelis? [ ](https://channel4news.substack.com/p/how-support-for-israel-in-us-is-declining) [ How support for Israel in US is declining ](https://channel4news.substack.com/p/how-support-for-israel-in-us-is-declining) Kiran Moodley · May 4 [ Read full story ](https://channel4news.substack.com/p/how-support-for-israel-in-us-is-declining) “Because the news media and the extremes of both parties are so willing to tell what I think is a false narrative.” Lauren chimes in: “Do you really think the actions of Israel have nothing to do with the shift in the sympathies?” “I think that’s very relevant,” he replies. “I just don’t think that people really have a full understanding.” Lauren again: “It sounds like you’re saying that the shift is due to how the atrocities are being described, as opposed to what the actual atrocities are.” “There have been some things that shouldn’t have happened,” David says. “I think the polling is being driven by politicians who are taking advantage of this issue.” Lauren then asks, “I’m curious what your response would be if my children were killed in an Israeli airstrike and someone said there have been some things that shouldn’t have happened?” A long pause from her father. “Any reference to my grandchildren has a very deep emotional impact on me. Well done,” he says. “I have an empathy for any civilian in war and I don’t mean to belittle those losses. The loss of any one life is a horrible thing. But it doesn’t make it a war crime and it doesn’t make it genocide.” Lauren and David cannot agree but tell me how proud they are of one another for sticking to their convictions and for agreeing to let me sit in on their conversation. I cannot thank them enough for their time, and hope their honesty informs and educates many people during such a fraught election. Abdul El-Sayed: The candidate testing the US - Israel relationship Thanks for reading our latest FourSight newsletter. Subscribe to receive free weekly newsletters from Channel 4 News. Subscribe Share Channel 4 News Leave a comment

Oct 29 • 8:01 AM EDT • Politics • channel4news.substack.com

Six popular sugar substitutes linked to faster brain aging

A study of nearly 13,000 adults found that people consuming the most artificial sweeteners experienced a 62% faster decline in memory and thinking skills, equivalent to approximately 1.6 additional years of brain aging. Six popular sweeteners were linked to faster cognitive decline, raising concerns about the long-term brain health effects of common sugar substitutes, although causation was not established.

Oct 29 • 8:00 AM EDT • Science • sciencedaily.com

A golden age of science is coming

It’s almost hard to remember, but just a few years ago, a lot of very smart people thought that science was in terminal decline. Respected researchers were writing papers with titles like “Are Ideas Getting Harder to Find?”, “Papers and patents are becoming less disruptive over time”, and “Slowed canonical progress in large fields of science”. In 1996, science writer John Horgan even published a book called The End Of Science: Facing The Limits Of Knowledge In The Twilight Of The Scientific Age. The fundamental idea was that the Universe only has so many insights to discover, and that we’ve picked the low-hanging fruit. It was the idea that Joseph-Louis Lagrange expressed when he said that “we cannot find more than once a system of the world to establish.” As the big ideas and the simple ideas get mined out, we’re forced to throw ever more brains at the mysteries of nature just to keep scientific progress going at a fraction of its old pace: It looked like science was hitting a wall. Then along came AI. It’s far too early to tell how much AI will eventually speed up the growth of total factor productivity. But already we can see signs of a speedup in science. Anthropic Founder Jack Clark assembled some of the hopeful data points in a recent lecture: [ Dror Poleg@drorpoleg "If you pick different parts of science, you see the same pattern show up: Progress is accelerating, and it has started to accelerate in the last two years." Jack Clark @jackclarkSF I’m speaking at the IMF in an hour about the singularity and why I believe it has begun and the choices we'll need to make. Watch live here: https://t.co/Hj9HzcXx5h 6:08 PM · Oct 18, 2026 · 21.2K Views 2 Replies · 10 Reposts · 123 Likes ](https://x.com/drorpoleg/status/2111882070376980529) Anthropic is accelerating its investment into drug discovery, and is already announcing some impressive preliminary results: [ BioTender@Junioryu136689 BREAKING: Anthropic unveils early results from six Claude-powered drug development collaborations. • 70% shorter CAR-T signaling domain • ~35,000 antibody designs • >10× tighter antibody binding • 89% less batch-record review time Still largely preclinical. Anthropic @AnthropicAI Over the past few months, Anthropic scientists have engaged in deep research partnerships with six organizations developing new medicines. We've also begun drug discovery efforts of our own. In doing so, we’ve learned much more about how Claude can support the many stages of 9:43 PM · Oct 27, 2026 · 11.2K Views 3 Replies · 24 Reposts · 205 Likes ](https://x.com/Junioryu136689/status/2115197821150495150) Claude also appears to be enabling rapid progress toward a treatment for food allergies. OpenAI, meanwhile, announced a possible breakthrough treatment for neurodegenerative disease. Meanwhile, Google Cloud Chief Scientist Pushmeet Kohli has a list of recent scientific advances that have been enabled by its new Gemini model, including breakthroughs in nuclear fusion reactor design, rare disease research, and quantum computing: [ Pushmeet Kohli@pushmeet Gemini 4 Argon is a step change in model performance. In recent weeks, it has had a transformative impact on the Science projects in our team at @GoogleDeepMind and our external collaborators, and helped make a number of remarkable advances across scientific disciplines. 🧵👇 4:47 PM · Oct 13, 2026 · 36.5K Views 8 Replies · 41 Reposts · 497 Likes ](https://x.com/pushmeet/status/2110049807385702623) But as cool as these stories sound, they’re just very minor, preliminary efforts. There are a number of reasons to think that AI is going to propel us into a golden age of scientific discovery. That age might not last forever — AI might still run into diminishing returns eventually. But the next few decades are probably going to be an absolutely amazing time for human science. The number of “effective researchers” is no longer limited The most important input into science is scientists themselves. Until this year, that meant human brains — talented, highly trained human brains. The number of trained human brains could be increased by sending more people to grad school, but only to a point — the smartest people tend to be sent into the hardest research fields first, and if you 10x the number of researchers, the average quality will go down. This constraint was already starting to bite, as Ekerdt and Wu argued in 2024: We argue that a substantial portion of the downward historical trend in U.S. research productivity is a composition effect resulting from self-selection in researcher ability and the dramatic expansion of the research sector…[W]e find that this composition effect has lowered average researcher ability by between 37% and 53%[.] And of course, low fertility was making the problem worse, because fewer children meant fewer people who were able to become future scientists. AI just blows up this constraint completely. If an AI agent can function as an autonomous researcher, there’s no constraint on the number of researchers in the world — you can just build more of them, by building more computer chips and data centers that enable the running of more AI agents. Whether or not massive hordes of agents can collaborate to solve individual problems much faster, increasing the number of agents allows them to tackle many different research questions in parallel. What’s more, these AI “researchers” can be trained incredibly quickly compared to human beings. A human scientist takes decades to train, and more years to reach the frontier of their research field by diligent reading and conversation. This is the “burden of knowledge”, and it’s commonly believed to be one reason ideas have been getting harder to find — by the time human scientists can get up to speed, they’re often so old that their ideas are no longer novel. AI just annihilates this constraint — it can assimilate the entire literature and reach the frontier of research extremely quickly, and it can also tell human scientists where the frontier lies without forcing them to discover that for themselves. It can also pivot to new research directions more easily than humans can. And there’s also a self-reinforcing economic cycle here. Because scientific advances enable higher GDP, they enable more resources to be invested into the creation of yet more electronic “scientists”. Now that doesn’t mean the amount of scientific research goes to infinity — there may still be some essential bottleneck task that human researchers are still needed to perform. There are some indications that AI’s progress on open-ended conceptual research tasks is slower than in other dimensions, and it may be that humans are still needed to provide some of this long-term conceptual thinking. I’d bet against this being true for much longer, but it might be true for a long time. Even in this most “pessimistic” case, though, the amount of effective capital that scientists can use to leverage their work just went up by a lot. AI eliminates the theory bottleneck Science proceeds by an iterative process of theory and experiment. The theory part of that cycle is typically short, but non-trivial — it took a couple of years after the blackbody radiation spectrum was observed for Max Planck to come up with the quantum hypothesis to explain it, and decades longer before quantum theory as we now know it was created. It took about a year for Watson and Crick to figure out the shape of DNA after the requisite data was gathered. AI will basically eliminate the theory bottleneck entirely — or at least shorten the turnaround time between experiment and theory by an order of magnitude. AI is an absolute beast at math. Recently, an OpenAI model solved some of the most important open problems in computer science, math, and theoretical physics, and no one even batted an eyebrow because that sort of triumph is becoming increasingly commonplace. One of those solutions was a proof that the Standard Model of Particle Physics could be mathematically well-defined — a problem that human theorists had so far been unable to tackle. Not all research relies equally on theory, but understanding novel experimental results almost always involves some important component of either mathematical or spatial reasoning. That part of the task has now been made much, much faster. And on top of that, science is now open to a greater number of humans who aren’t naturally good at theorizing. AI can read the whole literature Much of the work of human scientists involves reading and understanding endless amounts of papers and going to endless conferences and seminars. The purpose of that work is to understand the existing scientific literature. Understanding the literature allows scientists to do the following things: Come up with new ideas for hypotheses to test Avoid doing research that someone else has already done Synthesize approaches from different areas or fields AI can reduce this effort to almost zero. Consider this excerpt from OpenAI’s blog post about their new research into neurodegenerative disease: The team divided the analysis among thousands of AI agents powered by GPT‑Rosalind, an approach we call distributed biological reasoning. The agents examined a whole-brain CRISPR atlas…a dataset showing how gene disruptions affect different types of cells across the mouse brain. Each agent investigated a gene disruption, analyzed cellular responses, searched scientific literature, and proposed explanations for the results. Their reports were combined into a reasoning atlas linking genes, cellular effects, relevant publications, and possible biological mechanisms. The research team estimated that comparable human analysis and literature review, conducted one perturbation at a time, would take months to a year. The agents reproduced findings from human analyses while uncovering additional leads. Their assessments of novelty and scientific value also aligned with judgments from blinded human experts. These findings help prioritize further experiments needed to test the proposed biological mechanisms. Some of these insights point to new leads for understanding brain disease. [emphasis mine] This is one case in which parallel work by a large number of agents really does make a huge difference: [ Haider.@haider1 this is actually insane openai deployed thousands of GPT-Rosalind agents to analyze millions of mouse brain cells in 32 minutes, work that could take human researchers months to a year also the agents uncovered new leads for brain diseases like Alzheimer's and Parkinson's OpenAI @OpenAI GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in 2:41 PM · Oct 21, 2026 · 51.5K Views 26 Replies · 95 Reposts · 1.26K Likes ](https://x.com/haider1/status/2112917197903540516) Not only does instantaneous literature review vastly speed up the research process, but it allows AI to make novel conceptual leaps from combining approaches from wildly different fields of research. AI regularly does this in math research, combining results, approaches, and theorems from far-flung places that no human mathematician would have thought to combine. It can do it in science, too. Much of scientific innovation, historically, has been “recombinant” innovation — scientists applying insights from one field to another. With AI, essentially all research is now cross-disciplinary — AI can read not just the literature on a particular subject, but the literature on a million other subjects that might have produced useful techniques or insights for the problem at hand. Superscience So far, all of the factors I’ve listed are ways that AI can speed up science as it’s already done. I’ve basically described how AI can send gigantic hordes of superhumanly fast, superhumanly well-read, superhumanly mathematically gifted researchers to re-accelerate scientific discovery. But it’s also possible that AI will enable types of discovery — and ways of understanding the natural world — that no network of humans, no matter how large or how brilliant it was or how long it had to work, would ever be able to discover. In a post back in July, I wrote about how that might work: What if there are lots of…aspects of the Universe that [are] too complex to understand in terms of simple laws, but not so complex that they just dissolve into unknowable chaos? It’s possible that we can reliably control these complex phenomena with AI, even if we never reduce them to the kind of principles that we can teach a grad student in a textbook… Another way of saying this is that there may be laws of the universe that humans can’t understand but AI can. I call these “cloud laws” — causal regularities that can be exploited by technology, but which are too diffuse and complex for an individual human being to either intuit or communicate… Perhaps social sciences like economics, sociology, and political science obey similarly complex regularities, and AI can help us find them. Perhaps there are physical processes — plasma, or topological materials, or aerial turbulence, etc. — that obey cloud laws instead of chaos?… [H]uman collaboration is bottlenecked — it’s limited by our ability to intuit patterns at an individual level, and to communicate these patterns from one individual to another. AI, being a computer, just doesn’t have this sort of limitation; it can work with vast, diffuse patterns without having to break them into pieces or simplify them in order to compress them into the tiny pipelines of person-to-person explanation… If much of the Universe turns out to be ruled by cloud laws, we could be on the precipice of a scientific renaissance. In order to discover cloud laws, AI will need huge amounts of data about the natural world. AI figured out human speech by assimilating essentially all of the text humans have ever written. If it’s going to figure out hidden patterns in biology, neuroscience, materials science, etc., it’s going to need similarly massive amounts of data from physical instruments. That data will be far, far more than humans — individually or collectively — would be able to parse, label, characterize, or model. But AI was built to do this. If scientists simply build huge arrays of sensors to measure complex phenomena like the brain, the cell, the economy, etc., they may be able to feed this flood of data to AI directly and bypass human cognitive intermediation entirely. AI would then learn about the world directly, and it might learn things that humans never could. This “superscience”, if you want to call it that, would actually go beyond the kind of science humans have done heretofore. Many of the technologies it yielded would be beyond human comprehension — indistinguishable from magic. But to the AIs, they would make perfect scientific sense. In any case, it seems clear that the scientific slowdown that threatened human progress will now be delayed — at least for a while. Unless humans have somehow found most of the actual exploitable regularities in our Universe, we’re about to enter a new golden age of science. Subscribe Share

Oct 29 • 5:55 AM EDT • Science • noahpinion.blog

Global Health & WASH

The US National Institutes of Health reopened its center and program-project machinery in force. NIGMS is funding Collaborative Program Grants for interdisciplinary teams, NIAID opened both its Immune Tolerance Network and a next-generation R&D call, the NCI runs its Carcinogen Hazard Assessment Monographs program, the National Library of Medicine is funding institutional training in biomedical AI and data science, and NIH reopened its Centers for AIDS Research. The tell: these pay for standing centers and multi-year consortia at institutions with an existing funded research base, not one-off projects, so the fit is an established US research institution, not a single investigator. Disease-specific foundations are again funding the researcher, not just the research. The Parkinson’s Foundation opened its Paul Oreffice Innovations in Care Award and the National Ataxia Foundation its Research Seed Money Grant. The tell, the same one we flagged last cycle, is a named early-career or seed award that builds a pipeline of scientists committed to one condition, so what wins is a researcher willing to specialize. The post-USAID global-health money is routing through a State Department program statement and multilateral innovation funds. The US Department of State’s Bureau of Global Health Security and Diplomacy opened its Advancing Global Health Annual Program Statement, Grand Challenges Canada opened Nexa Lighthouse for climate and health innovation in Asia and the Pacific at USD $250,000 to $2,000,000, and CEPI opened a rolling call on vaccine-manufacturing analytics. The tell: the largest health money this cycle sits in a standing program statement and in staged innovation vehicles, not in a single bilateral grant. Total Estimated Funding Pool: ~$35.4M across discrete grants. (Separately, large national-formula envelopes not counted in this total: U.S. Department of State, Bureau of Global Health Security and Diplomacy (GHSD).) This post is for paid subscribers. This helps support the time and effort it takes to curate and organize these opportunities. Subscribe To keep this accessible to everyone who needs it, we’re happy to offer pay what you can rates. You can find more details here. New opportunities: Paul Oreffice Innovations in Care Award, Parkinson’s Foundation. *New!* *Closing soon!* The Parkinson’s Foundation created the Paul Oreffice Innovations in Care Award to fund clinicians rethinking how people with Parkinson’s disease receive care. The Foundation is using pilot funding to move promising ideas into testable projects, backing work across four lanes: strengthening community clinician capability, redesigning care models, building patient-centered technologies, and defining the minimum clinical datasets that make better standards possible. It wants hypothesis-driven, clinically grounded projects that can generate evidence strong enough to attract further funding. By opening the door to clinicians at every career stage and strongly preferring projects that involve people with Parkinson’s in their design, the Foundation signals that it values practical, patient-shaped innovation over prestige. The strongest fits are US-licensed clinicians with a focus on Parkinson’s and an institutional home for applied care research. Geographies: united states. Who can apply: Clinicians of all career stages, from fellows to established faculty, who are licensed to care for patients in the United States and have a significant focus on Parkinson’s disease. Physicians must have completed a neurology residency (or justify how their training pathway benefits people with PD); allied health professionals must hold an advanced degree, typically a PhD. Fellows, those in mentored positions, and those within two years of starting an independent position require a mentor and a mentor support letter. The sponsoring institution’s grants office is the authorized recipient and funds are disbursed to the institution. Funding amount: Maximum of $200,000 over two years; up to three awards. Targeted Sectors / SDGs: Health; Innovation; Science & Technology. Deadline: November 1, 2026. Learn more and apply here. Design and Deliver the Next EIT Health Bootcamps, EIT Health. *New!* *Closing soon!* EIT Health is opening its call for consortia to design and deliver the next generation of its health start-up bootcamps, funding the curriculum, masterclasses, mentoring, and investor engagement that turn early health ventures into fundable companies. The organization is using these learning paths to strengthen Europe’s health innovation pipeline across digital health evidence, deep tech and AI commercialization, cross-border investment, and patient access. What EIT Health wants to back is not a single course but durable delivery capacity built by partners who span industry, education, and research. Requiring multi-country consortia and a revenue-sharing stake in the programs signals that EIT Health expects these bootcamps to outlast the grant. The strongest fits are established training providers, universities, and industry partners with proven reach into health entrepreneurs. Geographies: Europe. Who can apply: Consortia only (individuals cannot apply), comprising a minimum of two and a maximum of five independent legal entities. Partners must cover at least two sides of the Knowledge Triangle (industry, education, research), including at least one industry organisation, and at least two entities must be legally established in different Horizon Europe countries. Funding amount: Foundational Learning Path: up to EUR €112,000; Thematic Learning Paths: up to EUR €124,500 per path (up to four thematic projects); up to EUR €610,000 total EIT Health funding available under the call. Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. Technology Transfer Offices & Entrepreneurship Support Call (Beyond the Lab: From Research to Venture), EIT Health. *New!* *Closing soon!* EIT Health is opening its Technology Transfer Offices and Entrepreneurship Support Call to fund consortia that will deliver the Beyond the Lab: From Research to Venture program for healthcare researchers. EIT Health is using the grant to build local capacity for turning laboratory science into incorporated start-ups, paying experienced technology transfer offices and entrepreneurship support providers to run masterclasses, structured mentoring, and a closing Pitch Day across two cohorts. It wants to back organizations that can walk researchers from discovery to company formation, not just teach theory. Requiring two transfer offices plus one venture-building provider signals that EIT Health values proven commercialization experience alongside academic reach. The strongest fits are European research-commercialization teams with a track record of moving health innovations toward investable ventures. Geographies: Europe. Who can apply: A consortium of two Technology Transfer Offices (representing higher education institutions or research organisations) and one Entrepreneurship Support Provider with demonstrated experience in venture building and start-up support. Applicants may apply for more than one learning path where they can demonstrate the required expertise and capacity for each. Funding amount: Up to EUR €77,000 in 2027 and up to EUR €77,000 in 2028 (up to EUR €154,000 total per consortium over two years). Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. EIT Health RIS Country Representatives Call (2027-2028), EIT Health. *New!* *Closing soon!* EIT Health is seeking organizations to serve as Country Representatives across eleven Regional Innovation Scheme countries in central and eastern Europe for the 2027 to 2028 period. The money funds a national anchor in each country, an organization that maps the local health innovation ecosystem, connects startups and researchers to EIT Health programs, and builds the stakeholder relationships that let health ventures grow. EIT Health is backing local capacity rather than individual projects, which is why it accepts both single organizations and national consortia that span education, research, and industry. The requirement for co-financing signals that it wants representatives already embedded in their national systems. The strongest fits are established ecosystem builders with deep ties to health innovation stakeholders in one eligible country. Geographies: Croatia; Czech Republic; Estonia; Greece; Hungary; Latvia; Malta; Romania; Serbia; Slovenia; Turkey. Who can apply: Registered legal entities established in one of the eligible EIT RIS countries. Single organisations or national consortia may apply. Consortia must include at least two sides of the Knowledge Triangle (education, research and industry), and all consortium partners must be established in the same eligible country. Suitable applicants have demonstrated experience in healthcare innovation ecosystem development, innovation support and entrepreneurship, start-up acceleration, technology transfer, research and higher education, business support, and stakeholder engagement, with strong links to national innovation stakeholders. Funding amount: Up to EUR €182,000 per Country Representative (maximum funding per project); total call budget up to EUR €1,274,500; EIT Health funds up to 60% of total eligible project costs. Targeted Sectors / SDGs: Health; Innovation; Science & Technology; Economic Development & Livelihoods. Deadline: November 2, 2026. Learn more and apply here. Architects of Trust: Community-Driven Demand Creation for New TB Vaccines, Treatment Action Group (TAG). *New!* *Closing soon!* Treatment Action Group, with funding from Wellcome, is opening its Architects of Trust call to help communities prepare for the new tuberculosis vaccines now moving through late-stage trials. The money backs civil society and community-based organizations to raise awareness, surface local questions and concerns, and press policymakers toward equitable national rollout. By pairing each grantee with an advocacy mentor and running a strategy workshop alongside the Global TB Vaccine Forum, Treatment Action Group is building a durable advocacy bench rather than funding one-off outreach. The two-stage design, starting with a short expression of interest, signals that fit and community rootedness matter more than polished proposals. The strongest fits are locally trusted groups with real TB, immunization, or health advocacy experience and a committed project lead. Geographies: Brazil; Ethiopia; India; Indonesia; Kenya; Malawi; Mozambique; Nigeria; Peru; Philippines; South Africa; Tanzania; Vietnam; Zambia. Who can apply: National, subnational, or regional civil society organizations (CSOs) or community-based organizations based in one of the 14 eligible countries or in Eastern Europe/Central Asia regional networks, with experience in TB, immunization, or other health advocacy and in community engagement or policy advocacy; well integrated into stakeholder networks with membership or affiliation to other CSO or community networks; naming a dedicated project lead (’architect of trust’) who can attend the April 2027 Zaragoza forum in person; and holding (or committing to adopt) organizational policies on safeguarding (bullying, harassment, abuse, and harm), equity, diversity and inclusion, and legal compliance, research practice and governance. Funding amount: Grants of up to US$45,000 will be awarded to 8 CSO partners across 14 high-TB-burden countries plus regional networks in Eastern Europe and Central Asia; each grant funds 12 months of work. Targeted Sectors / SDGs: Health; Governance; Policy & Advocacy. Deadline: November 4, 2026. Learn more and apply here.

Oct 29 • 3:37 AM EDT • Health • impactfunding.substack.com

Health directors say region is 'well-protected' from measles, but obstacles remain

As a historic measles outbreak continues to spread across the commonwealth, state and local health officials met in Cranberry Wednesday to discuss vaccination...

Oct 28 • 5:41 PM EDT • Health • post-gazette.com

From Business to Beluga Whales: Inside Briana Maltez’s Marine Biology Journey

Beneath the hum of filtration pumps and the rhythmic trickle of saltwater tanks, Briana Maltez is completely in her element. The Texas A&M University at Galveston marine biology major is following her lifelong love of animals—and that passion drives her pursuit for a second bachelor’s degree in a field that endlessly ignites her curiosity.As a native of nearby Sugar Land, Maltez did not initially set out toward coastal science. She initially earned a degree in agricultural business through the Texas A&M RELLIS campus in Bryan, but her subconscious fascination with ocean life grew into an unignorable question during her time there: What if? Photo courtesy of Briana MaltezThe query continued to plague her until a turning point came during a Florida trip to near the end of her first degree. Up-close encounters with marine life reignited a childhood dream and shifted her trajectory toward the sea. Yet, stepping into an entirely new field required a leap of faith. Faced with the daunting prospect of starting over, Maltez placed her trust in Texas A&M Galveston as the premier marine biology program in the state. Deciding that she would never feel satisfied unless she tried, she applied—finding the resolve to face the demanding science curriculum head-on.Any lingering doubts vanished during her first semester on the island campus. The close-knit campus environment and small class sizes allowed Maltez to build immediate connections with her professors and peers—a welcoming backdrop where her love for ocean stewardship could truly take root.“I instantly fell in love with the campus and the small classes,” Maltez recalled. “I was like, ‘Yep, I’m so happy I came here.'”Before long, Maltez found a second home inside the university’s Sea Life Facility. Designed to mirror complex, large-scale aquarium infrastructure on a manageable scale, the space offered Maltez a safe training ground to grow familiar with system maintenance and water chemistry under the tutelage of Sea Life Facility Manager Katie St. Clair. While tending to the tanks there, she grew especially fond of watching the facility’s resident clownfish breed and care for their clutches.“Katie definitely wants us to learn, ask questions, and get hands-on experience,” said Maltez. “So, it has been great having her help with getting pre-experience before doing it in the real world.”That hands-on experience quickly sparked a deeper interest in animal husbandry—the daily art of monitoring the animal’s diets, observing their behavior, and maintaining the aquarium’s overall health. Eager to turn those newfound practical skills into technical credentials, Maltez even earned certifications in life support systems and water quality management through Aquatic Animal Life Support Operators courses.Maltez’s passion soon extended beyond campus boundaries. During a summer study abroad program in South Caicos, Turks and Caicos, Maltez immersed herself in underwater field research. In addition to learning about local history and ecotourism impacts, she snorkeled daily, utilizing drones and hydrophones to record underwater bioacoustics and listen to the often-missed crackles of snapping shrimp, fish, and lobster larvae. Maltez at SeaWorld San AntonioPhoto courtesy of Briana Maltez“What you don’t realize is that there’s so many animals around you, but because they sense, you already, they run away,” Maltez explained. “I think that’s really cool to experience, because you don’t even think about that when you travel.”Yet, among all her academic adventures, a week-long course at SeaWorld San Antonio through MARB 302 stands out as a defining milestone. Camping on-site alongside fellow marine biology majors, Maltez gained behind-the-scenes access to professional veterinary and husbandry operations, building lasting friendships and even interacting with penguins in the snow.The undeniable highlight of the trip was face-to-face interaction with beluga whales. Having admired the titanic cetaceans for years, getting to learn directly from their trainers solidified her ultimate aspiration: to care for belugas and contribute to conservation research supporting wild populations in Alaska.“They are one of my favorite animals, and I had heard so much about them,” said Maltez. ”Getting to see them up close was an amazing experience.”When she is not analyzing marine environments, Maltez documents campus life through her camera lens. As a photographer for the Nautilus student newspaper, the Yell Leaders at Midnight Yell, and the Shark Scholars club, she brings the university’s passionate energy into sharp focus. With less than a year remaining until graduation, Maltez looks back on her decision to return to school with gratitude. Taking her journey one day at a time helped her push through demanding coursework, unlocking opportunities she once thought were out of reach. Today, Maltez stands as a compelling example of what happens when passion meets purpose: By trusting her drive and embracing every hands-on experience, she has transformed a second chance at college into an opportunity to dive into a career beneath the waves.

Oct 28 • 4:30 PM EDT • Business • news.galveston.tamu.edu

‘I don’t really get into politics’: Kirk Herbstreit headlined Republican fundraiser despite saying ‘I don’t really pick sides”

Kirk Herbstreit insisted last month that he doesn’t follow politics after College GameDay drew criticism for giving Sen. Ted Cruz a platform to promote a bill that ESPN has a stake in. But a new report suggests that the ESPN analyst is a little more politically engaged than he let on. According to a new…

Oct 28 • 1:06 PM EDT • Politics • sports.yahoo.com

FDA scientists opposed the Trump administration’s effort to ease peptides access

Health Secretary Robert F. Kennedy Jr. says he’s a fan of the unproven, injectable substances.

Oct 28 • 12:15 PM EDT • Health • twincities.com

FDA scientists opposed the Trump administration’s effort to ease peptides access

Health Secretary Robert F. Kennedy Jr. says he’s a fan of the unproven, injectable substances.

Oct 28 • 12:15 PM EDT • Health • baltimoresun.com

Nintendo joins Best Buy for midnight Zelda 40th Anniversary Switch 2 restock launch

📅 The Zelda 40th Anniversary Switch 2 releases on Thursday, October 27 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert when stock appears 😲 Nintendo Store held a surprise restock on October 26 and is holding a midnight launch event on November 5 🙏 Other retailers may be holding back stock for launch day, too Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe We’re expecting to see a Zelda 40th anniversary Switch 2 restock tomorrow at major retailers like Walmart, as the console and Pro Controller are set to launch. However, Nintendo has joined Best Buy in announcing a midnight launch event for The Legend of Zelda: Ocarina of Time on November 5, where limited quantities of the special edition console will be available. There is a catch, though. To attend the in-store event, which will be held on November 4 at Nintendo San Francisco and November 5 at Nintendo New York, a Warp Pipe Pass is required, which means capacity will be limited. If you’re lucky enough to receive a Warp Pipe Pass (they’re currently fully booked), you’ll be able to purchase The Legend of Zelda 40th Anniversary Edition console, Zelda 40th Anniversary Nintendo Switch 2 Pro Controller and display stand, the Zelda 40th Anniversary Switch 2 Pro Controller on its own, and the Zelda 40th Anniversary carrying case and screen protector. Purchases will be limited to one “per customer” and will be sold on a “first come, first served basis.” Why you should follow our Zelda Switch 2 restock tracker Obviously, many will be looking to receive the Zelda Switch 2 before November 5, and an instore event isn’t exactly ideal for many. That’s where our exclusive Zelda Switch 2 restock tracker comes in, as we’re providing up-to-the-second US store inventory checks. Those who follow Matt Swider on X and turn on notifications will be the first to know when new stock is live, as you can see in the post below. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2114758291322757239?s=20) Zelda Switch 2 console in stock at the Nintendo Store nintendo.com/us/store/produ… 4:37 PM · Oct 26, 2026 · 67K Views 18 Replies · 4 Reposts · 75 Likes We’re strongly expecting retailers like Walmart to have stock on launch day, especially as it’s the largest retailer in the US. Cancellations can also occur in the run up to release, meaning more stock is made available that was previously taken. Thursday and Friday mornings is also when Walmart tends to offer restocks online. We’re predicting other retailers like Target, GameStop and Amazon will also get a new wave of consoles on launch day, and we’ll notify you if and when any Zelda Switch 2 restocks appear. You can trust our restock tracker as we helped over 400,000 people buy Sony’s console when it was in and out of stock for two years. We’ve since made it our goal to help our subscribers purchase hard-to-find items. We’ve done the same with the PS5 30th anniversary edition and many more in-demand products. Up next: Zelda 40th Anniversary Switch 2 Pro Controller restock looks increasingly likely at Nintendo Store Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.

Oct 28 • 10:43 AM EDT • Technology • theshortcut.com

Corning’s American Tradition of Knowledge in Materials Science

Founded in 1851 in upstate New York, where it remains, Corning is a manufacturer of specialized glass that has a market capitalization of over $100 billion as of October 2026 (GLW), annual revenues approaching $20 billion, and nearly 70,000 employees worldwide.1 Corning is the world’s leading manufacturer of touchscreen glass, one of the world’s leading manufacturers of optical fiber for long-distance telecommunication, the leading U.S. manufacturer of polysilicon for solar panels, and one of two suppliers of glass for extreme ultraviolet (EUV) photomasks needed to make the world’s most powerful chips with ASML machines. Optical fiber is also increasingly crucial to expand the computational capacity of AI data centers with optical networking. Corning is a rare jewel of the American Industrial Revolution that has not just remained competitive to the present day but repeatedly enabled technological transformations: it developed the glass for Thomas Edison’s first light bulbs in the 1880s, invented optical fiber cable in the 1970s, and developed the “Gorilla Glass” touchscreens for Apple’s iPhones that kicked off the global smartphone revolution in the 2000s. Corning’s leading tradition of knowledge in materials science has allowed it to stave off successive waves of competition over the decades from Europe, Japan, and now China.

Oct 28 • 10:10 AM EDT • Science • brief.bismarckanalysis.com

Politics is medicine on a large scale

In February 1848, a 26-year-old doctor named Rudolf Virchow arrived in Upper Silesia, a poor, rural corner of Prussia that’s now part of Poland. A typhus epidemic was killing thousands, and the Berlin government wanted a doctor to assess how to contain this pathogen, advise local authorities, and propose a plan. Virchow spent a few weeks going from villa…

Oct 28 • 7:40 AM EDT • Politics • yourlocalepidemiologist.substack.com

Bruno Fernandes: Man Utd head coach Michael Carrick and club captain hold clear-the-air talks ahead of Chelsea fixture

Manchester United captain Bruno Fernandes was an unused substitute in their 3-0 defeat against Bournemouth after being dropped by Michael Carrick; Man Utd head coach will take Saturdays game against Chelsea with Fernandes now in contention after talks on Tuesday

Oct 28 • 6:39 AM EDT • Sports • skysports.com

Fresno nonprofit launches effort to combat youth substance use

Fresno nonprofit USEF is developing a youth substance-use prevention coalition, with plans for research involving Stanford experts.

Oct 27 • 7:58 PM EDT • Business • thebusinessjournal.com

Who Owns What: The Watermania Waterpark Richmond May Expropriate

[There is often a lack of transparency around land ownership in BC. Who Owns What is an ongoing series by The Realist focused on interesting land ownership stories. Have a suggestion for a future story? Email: howardchai@substack.com.] Earlier this month, CBC and Richmond News reported that the City of Richmond is planning to expropriate Watermania, the waterpark located at 14300 Entertainment Boulevard near the Richmond Ice Centre. The City of Richmond currently leases the property from a private owner — 14300 Entertainment Blvd. Investments Ltd. — and the lease is set to expire in March 2027. According to the reports, the two sides have been unable to agree on terms of the lease renewal and the City has since served a Notice of Expropriation, saying it wants to secure “essential community services,” according to CBC, with outgoing Mayor Malcolm Brodie telling CBC that “Watermania is an important recreation facility for our community, and the city’s goal is to secure its long-term future.” Richmond News added that because the expropriation is not for a linear easement like a sewage line or rapid transit, an inquiry can be requested, and one has been scheduled for November 30 to December 4, according to CBC. What was left out of both stories, however, is who the City would be expropriating Watermania from. According to the Land Owner Transparency Registry, 14300 Entertainment Boulevard is legally owned by 14300 Entertainment Blvd. Investments Ltd. and that numbered company is controlled by a Chinese individual named Hai Feng Zhu, who primarily resides in the Jilin province. The registered address of 14300 Entertainment Blvd. Investments Ltd. is 3899 Cartier Street in Vancouver, a mansion in Shaughnessy that BC Assessment values at $10,423,000. The home at 3899 Cartier Street has previously been tied to Kevin Sun of Sun Commercial by reporter Sam Cooper when he was with the Vancouver Sun in a report noting that Sun had an associate named Hai Feng Zhu who is a director of SunOil Ltd., as confirmed by the company’s filings. Another person mentioned in both the report and filing is Denise She. A search of Hai Feng Zhu in the Land Owner Transparency Registry reveals that Zhu also owns four other properties in British Columbia. The Realist then used the PIDs1 to identify the addresses, finding that the two parcels with PIDs beginning 014 are two parcels that form 1155 Bidwell Street in Vancouver and that the two parcels with PIDs beginning 015 are two parcels that form 1755 Davie Street. 1755 Davie Street is the Best Western Plus Sands, 1155 Bidwell Street is a surface parking lot, and both are held under 0993956 B.C. LTD., which is controlled by Hai Feng Zhu alongside the aforementioned Kevin Sun and Denise She, among others. The Best Western Plus Sands is listed under Sun Commercial’s portfolio and Sun Commercial also previously sold the Richmond Ice Centre to the City of Richmond for $32 million in 2019. Denise She, Peter Cheng De She, and Julia MiMi Yang also control 1078635 B.C. Ltd., which owns 1707 Davie Street, the small retail building that sits between 1755 Davie Street and 1155 Bidwell Street. Governments in British Columbia have a tendency to overpay for real estate, so it’ll be interesting to see how much the City of Richmond pays for Watermania if they do end up expropriating the property. BC Assessment values 14300 Entertainment Boulevard at $49,397,000. The assessed value is dated to July 1, 2025 and is a small decline from the previous assessment of $52,584,000. The rest of this story dives into Sun Commercial and $159 million in sales it made last year to KingSett Capital. Become a paid subscriber for all the details. Subscribe Sun Commercial Sun Commercial is based out of the City Square Shopping Centre at 555 W 12th Avenue in Vancouver, which it acquired in 2019 for $225 million, and also has an office located at 415 Yonge Street in Toronto.

Oct 27 • 7:37 PM EDT • Entertainment • howardchai.substack.com

Animals Starves while the Kardashians Miss the Charts Again

(Welcome to my weekly streaming ratings report, the single best guide to what’s popular in streaming TV and what isn’t. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. If you were forwarded this email, please subscribe to get these insights each week.) Before we get going, I’d like to offer congratulations to Jonathan Funke, whose suggestion “midflicks” won the poll for what I should call straight-to-streaming films which aren’t big or cinematic enough to go to theaters but seem too expensive for a TV movie. It’s so useful a term, I just used it last week! Now I just need to add this term to my data dictionary! Okay, on to this week’s issue. We’re starting out looking at Netflix/Ben Affleck’s latest crime thriller, Animals. I’ll also look at Disclosure Day heading to Peacock (it did better than you’d remember in theaters...) and a new movie based on toys. Plus, a long-time streaming flop returns for its eighth season...will it finally chart? (No.) Will anyone at Disney care? Probably not. All that, plus another look at new shows landing on streaming on 1-Oct from Reelgood, what streamer hasn’t had a film make the Luminate charts since August, Reacher’s long run on the charts, M_onster: The Lizzie Borden Story’s_ short run, the top shows in 2026 according to Samba TV, all the flops, bombs and misses, and a whole lot more. And I mean that last part: putting this week’s issue together, I assembled OVER 25 images, most of which are bespoke looks I made just for this report. Really, publishing articles like this takes the work of writing two articles: one is the narrative and the other is making charts/graphs. Let’s dive right in! (Reminder: The streaming ratings report focuses on the U.S. market and compiles data from Nielsen’s weekly top ten viewership ranks, Luminate’s Top Ten Data, JustWatch and Reelgood interest data, Samba TV household viewership, company datecdotes, Netflix hours viewed data, Google Trends, and IMDb to determine the most popular content. While most data points are current, Nielsen’s data covers the week of October 5th to October 11th, 2026. You can find a link to my terminology here.) Subscribe Film - Netflix’s Latest Star-Studded Thriller Goes For Glory The tempting angle for anyone writing about streaming film this month, like yours truly, is to ask, “Is this why Dan Lin lost his job at Netflix?” Take Animals, the Ben Affleck-starring-and-directing, Artists Equity-produced crime thriller that opened on 9-Oct. (Kerry Washington and Gillian Anderson are also in it.) If it did really well, then one could argue that Lin has another success on his resume. If it underperformed, then it’s another example of a Netflix underperformance this year. So where did Animals fall? Kinda in the middle, but that means it’s more “not a hit” than “big hit”. On Nielsen, it opened to 12.0 million hours, and here’s how that stacks up for 2026 films so far this year: Obviously, that’s not great. It’s both under my 15 million opening bar for “fine” for a Netflix film and 20 million bar for “great” opening. It did a bit better on Samba TV, getting to first place. That’s very, very good, though again, looking at the Nielsen data, it probably means that it was a light week overall. Luminate’s data is a bit closer to Samba TV’s, tied for 17th all time for single weeks since May of 2024: To top it off, no one seemed to like it. It has a 33 on Metacritic and only a 5.7 on IMDb. Both of these numbers could have been impacted by the stories about Affleck’s comments about using AI to make the film. Given the controversy, the film might not have been as bad as the ratings suggest, but it’s also not a bullish sign. All to say…yeah, on net this film isn’t a point in Dan Lin’s favor. At this point, Netflix’s slide has been long enough—going on since February—that I’m almost tempted to lower the bar for what a “hit” is on streaming. Post-February of 2026 or so, it seems like straight-to-streaming films just haven’t hit the same heights as they did from 2022 to 2025. Before we head onto the “Quick Hits” for film, I want to shout out a fellow newsletter whose articles I’ve been loving this year, LA Material, a new LA-based news outlet. For just a highlight of my favorite articles since July... I loved this article on Ghost Town, a group on Venice that clears homeless encampments. As a Los Angeleno, obviously I adore their articles on LA parking issues. Their article on illegal parking tickets got the City Council to address the issue! Also check out their article on people parking in medians. Check out their deep dive on what went wrong with the LA Jazz Festival and how it fell apart, or what’s wrong with USC’s finances. Finally, they wrote up a voter guide on voter guides for the LA General Election. So meta! In search of a city? L.A. Material is an independent news outlet covering the people, politics, culture and glorious chaos shaping Los Angeles. L.A. Material brings you intel on the city you can’t get anywhere else. From exploring how Reddit short stories became Hollywood’s hottest commodity to reporting on the survival jobs keeping entertainment workers afloat. And answering, once and for all, why the AMC Burbank escalator is always broken. Through their newsletters, podcast, videos, events, and member community, L.A. Material is designed to help Angelenos connect to Los Angeles and each other. Sign up now for the free weekday newsletter. Quick Notes on Film Steven Spielberg’s latest film, Disclosure Day, came to Peacock on 9-Oct, and I’ll admit that, after pulling its stats, I did a pinch of a double take. As I wrote throughout my deep, deep, deep dive on summer box office/Obsession/Backrooms/IP/superheroes, oftentimes the film media discusses films as “flops” or “misses” or “hits” without clarifying what they specifically mean. Since Disclosure Day didn’t make $250 million in the US or $500 million globally, it was definitely a disappointment by Spielbergian standards, who is the highest-grossing director of all time, and arguably even more ahead in adjusted grosses. But it did make $245 million globally on a $115 million budget, so it isn’t as big of a miss as I remember. That’s still probably not enough to break even in the theatrical window, when you factor in marketing costs…but it’s close. And it grossed a lot more even in the US than some titles with about ten times more coverage. Anyways, lots of preamble to say this one only did 4.5 million hours according to Nielsen, so it did make the charts, but on the low end. Here’s how it stacks up to other Peacock titles: Apple TV (née +) followed up their “success for them” Mayday with Matchbox The Movie. This one doesn’t look like a success even for them, but at least it’s not a miss. Apple/Skydance clearly tried to take advantage of the success of Barbie at the box office—let’s greenlight all the toy properties!!!—but of course, this didn’t make it to theaters. And it stars John Cena, who, as I argued earlier this summer, NEEDS to get his movies back in theaters. Anyways, this one has mixed-to-bad numbers. It missed the Samba TV and Nielsen charts in its first week, but did make Luminate with 7.1 million hours. That’s just enough to not be an outright miss, and about half what Mayday did earlier this summer. Speaking of Apple Studio’s Mayday, it ended up lasting five weeks on Luminate, which isn’t bad for Apple TV. On Nielsen, it had a three-week run, racking up 13.5 million hours total. Again, like Matchbox, the issue is the budget; I doubt that this viewership earned enough to justify that budget. Also, to be clear, neither of these films are “midflicks”; both should have gone to theaters. Toy Story 5 is not hanging around on the streaming charts on Disney+, so it’s not as leggy as either Zootopia 2 or Moana 2, and definitely not in the same class as Encanto. (It did make all the money at the box office, so Disney is going to be fine…) The Breadwinner on Netflix (from Sony) is down to 3.9 million hours in its third week. It only lasted for one week on the Samba TV charts. Netflix’s Doing Life had a smaller-than-normal binge release curve bounce, only going to 7.1 million hours from 6.0 to start, but it made Samba TV at fifth place in its second week. The Netflix documentary, The Widower: Til’ Death Do Us Part, also had a small binge release curve bounce to 6.5 million hours, but did make a second week on Samba TV. Meanwhile, Netflix’s Unabomber fell off after two weeks on Nielsen—which is not great at all—and Demon Slayer fell off after just one week. Over on Luminate, the two smaller titles The Swan: Behind the Mirror and Kill. Bury. Print both fell out of the Luminate top ten charts. The story of library film at the first of the month is the arrival of the Ice Age films on Netflix. Now, here’s a small example of optimizing your library that even Netflix could do better. Say you want to rent/license a new film series from Disney**.** A streamer could pay a big paycheck and then drop each Ice Age film on the exact same day of the month, the fourth of October. That’s one choice. In contrast, the streamer could have released each film one week apart, and make each one a mini-event for folks watching Ice Age films. Or even roll them out monthly. Netflix opted for the former strategy, and as a result, only three of the films made the Nielsen charts this week. The “Miss of the Week” goes to Tubi’s YA-ish horror film_, R.L. Stine’s Pumpkinhead 2_, which didn’t even make the Luminate charts like Tubi films usually do, or, should I say, “used to”? Tubi films, most of which are straight-to-streaming, used to reliably make the Luminate film charts (which only covers straight-to-streaming films), but a Tubi film hasn’t made it since August. The first Pumpkinhead got 1.4 million hours last year according to Luminate. As I wrote about this film before, it seems to be a bit muddled in terms of age: too scary for young kids but probably not scary enough for older kids. Speaking of Luminate, Netflix’s latest doc about a comic (expect more docs about comedians all month), Who Is Martin Mull?, flopped, getting just 200K and 700K hours according to Luminate. Three other film/special misses belonged to Hulu, including a standup special, Jamie Foxx: Take Care of Yourself, Neon’s latest horror film, Hokum, which made $17 million in the US, and a Family Guy Halloween special. (That last one was only 22 minutes, so it’s not a surprise it missed.) Finally, another Netflix standup special missed the charts, Mojo Brookzz: I Know You Lying missed too. I can confirm last week’s misses, most notably Paramount+’s Jackass: Best and Last, MUBI’s Teenage Sex and Death at Camp Miasma and HBO Max’s Evil Dead Burn. Television - I Can’t Visualize Nothing: The Kardashians Story Normally, in the mini-dive essays that open the Streaming Ratings Report, I focus on shows that do well or, at the very least, make the charts. Why? Because as I’ve said time and again, I can’t visualize nothing like, say, the Kardashians’ TV shows. Here’s the TV debuts chart for this week with a missing spot for The Kardashians, whose eighth season just landed on Hulu:

Oct 27 • 6:17 PM EDT • Entertainment • entertainment.substack.com

WV contributes federal health funds to breast cancer screenings, substance abuse recovery, more

The state of West Virginia will contribute millions of federal health dollars to help those in substance abuse recovery return to work, expand breast cancer screenings and more, Gov. Patrick Morrisey’s office has announced recently.

Oct 27 • 3:14 PM EDT • Health • westvirginiawatch.com

Sabato's Crystal Ball moves Senate race, CD 13 in Democrats' direction

All ratings sites have shifted a substantial number of races in Democrats’ direction as the Nov. 3 election nears.

Oct 27 • 2:25 PM EDT • Politics • floridapolitics.com

New medical framework redefines women’s heart health starting at puberty

The American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine released landmark publications that redefine women's heart health, starting at puberty.

Oct 27 • 12:53 PM EDT • Health • news-medical.net

Zelda 40th Anniversary Nintendo Switch 2 restock signals good news for launch day buyers

📅 The Zelda 40th Anniversary Switch 2 releases on Thursday, October 27 🚨 Our Zelda Switch 2 restock tracker @mattswider on X will send out an alert when stock appears 😲 Nintendo Store held a surprise restock yesterday, which is good news for other retailers 🙏 It suggests other retailers may be holding back launch day stock, too Walmart: Zelda Switch 2 console Best Buy: Zelda Switch 2 console GameStop: Zelda Switch 2 console Target: Zelda Switch 2 console Nintendo: Zelda Switch 2 console 🚨 We’re tracking Zelda Switch 2 stock updates. If you’d like to know when more stock arrives, follow Matt Swider on X and turn on notifications. You can also become a free or paid subscriber to The Shortcut to help support our work. 🚨 🚨 Want the Zelda 40th Anniversary Switch 2? Drop your email for restock alerts before it sells out. ⤵️ Subscribe We predicted that a Legend of Zelda 40th Anniversary Switch 2 restock would happen on launch day, October 29, and we’re now even more confident after the Nintendo Store’s surprise restock yesterday. Our followers were the first to know that the Zelda Switch 2 was back in stock at the Nintendo Store, and the console even promised to arrive on launch day if you managed to secure one. [ Matt Swider (The Shortcut)@mattswider ](https://x.com/mattswider/status/2114758291322757239?s=20) Zelda Switch 2 console in stock at the Nintendo Store nintendo.com/us/store/produ… 4:37 PM · Oct 26, 2026 · 67K Views 18 Replies · 4 Reposts · 75 Likes It strongly suggests that other retailers such as Walmart, Target, GameStop, Amazon and Best Buy will have more units – albeit in limited quantities – on launch day for those who currently don’t have a pre-order. Retailers often hold back stock for launch day buyers who haven’t pre-ordered. Cancellations can also occur in the run up to release, meaning more stock is made available that was previously snapped up. Zelda Switch 2 restock – why Walmart will have stock Walmart historically holds back extra stock for launch day, and we’re expecting the same to happen on October 29. As the largest retailer in the US, it usually has the biggest stock allocation, and Thursday and Friday mornings is when the retailer tends to offer restocks online. As we mentioned previously, Nintendo was also a retailer to watch – and it went live with a restock earlier than we thought. It had previously promised the Zelda 40th anniversary Switch 2 would be “replenished”, and it offered a limited amount of stock for those who were lucky enough to snag one. (Hint: Followers of Matt Swider on X and our restock tracker were first in line.) We’re expecting other retailers like Target, GameStop and Amazon to get a new wave consoles on launch day, and we’ll notify you if and when any Zelda Switch 2 restocks appear. Why you should follow our Zelda Switch 2 restock tracker Remember when you couldn’t find a PS5 for nearly two years? Not our followers. We helped over 400,000 people buy Sony’s console when it was in and out of stock, and we’ve since made it our goal to help our subscribers bag hard-to-find times. We’ve done the same with the PS5 30th anniversary edition, Nintendo Switch 2, and many more in-demand products. With up-to-the-second US store inventory checks, The Shortcut and Matt Swider on X offers exclusive Zelda 40th anniversary Switch restock updates. You’ll also receive an instant notification on X (if set to on) as soon as new stock arrives. Up next: Zelda 40th Anniversary Switch 2 Pro Controller restock looks increasingly likely at Nintendo Store Subscribe Adam Vjestica is The Shortcut’s Senior Editor. Formerly TechRadar’s Gaming Hardware Editor, Adam has also worked at Nintendo of Europe as a Content Marketing Editor, where he helped launch the Nintendo Switch. He also runs a retro gaming YouTube channel called Game on, boy! Follow him on X @ItsMrProducts.

Oct 27 • 11:35 AM EDT • Technology • theshortcut.com

A Doctor’s Take On New Menopause Guidelines

TUESDAY, Oct. 27, 2026 (HealthDay News) — Many women I see in my practice have questions about menopause and hormone therapy. The newest guidelines from the American College of Obstetricians & Gynecologists (ACOG) bring some welcome clarity. For years, the Women's Health Initiative study caused a ...

Oct 27 • 8:00 AM EDT • Health • usnews.com

Vadim Gladyshev and the Science of Aging

Oct 26 • 8:00 PM EDT • Science • erictopol.substack.com

Matthew Perry’s sister explains how his addiction struggles inspired her career as a psychotherapist

Matthew Perry’s sister, Mia Perry Bowick, explained how the ‘Friends’ star’s substance use disorder impacted her decision to become a psychotherapist.

Oct 26 • 5:48 PM EDT • Entertainment • ew.com

Shared framework aims to redefine heart health for girls and women

The American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine have released a publication that redefines ...

Oct 26 • 5:40 PM EDT • Health • medicalxpress.com