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Alexander Lake Lodge in Cedaredge offers rare business opportunity

This weekend’s unique commercial property is a mountain retreat located on top of the Grand Mesa near Cedaredge, CO.

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Jul 4 • 11:30 AM EDT • Business • gjsentinel.com
Rita Süssmuth, trailblazer in German politics, dies aged 88

She dared to break taboos, advocated for women's rights and took part in a failed attempt to oust Chancellor Helmut Kohl as chairman of the CDU. Former President of the German Bundestag Rita Süssmuth has died aged 88.

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Feb 1 • 10:47 AM EST • Politics • dw.com
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In memoriam: Pavithra Sundaresh, senior, College of Science

Sundaresh, a senior in the School of Neuroscience, passed away on March 30. She was 20 years old.

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Apr 17 • 1:46 PM EDT • Science • news.vt.edu
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Raiders sign RB Dare Ogunbowale

The Raiders have added a veteran running back.

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Aug 6 • 10:50 AM EDT • Sports • nbcsports.com
Dumb Co dared me to trade my iPhone for a hacked flip phone

Dumb Co sells flip phones that sync to your smartphone, bridging the infinite connectivity of the iPhone and the unrealistic limitations of an early 2000s relic.

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Jul 10 • 12:06 PM EDT • Technology • techcrunch.com
7 Four-Cylinder Sports Cars That, Dare We Say, Could Be Called Super

Four-cylinder supercars include the ASA 1000 GT, Lotus Esprit and Emira, Porsche 924 Carrera GT and 968 Turbo S, BAC Mono, and Alfa Romeo 4C.

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Oct 4 • 1:25 PM EDT • Technology • jalopnik.com
‘Daredevil: Born Again’ Trades In Faith For Politics To The Series’ Detriment

Very few superheroes wear their faith on their sleeves like Daredevil. But the Season 2 opener for Disney+ series “Daredevil: Born Again” has pulled back on those elements. If that reflects the rest of the season, it will be to the show’s detriment.

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Mar 30 • 6:00 AM EDT • Politics • religionunplugged.com
Relic Entertainment Launches <em>Company of Heroes 3: Dare & Destroy</em> Battlegroup DLC

'Dare & Destroy' Battlegroup DLC now launched on Steam, each faction gets one.

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May 14 • 8:00 AM EDT • Entertainment • gamespress.com
The NFL Achieves Parody

Don’t you dare change my headline editors, I know what I said.

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Dec 30, 2025 • 3:55 PM EST • Sports • acmepackingcompany.com
How Trump will use his State of the Union address to appeal to skeptical midterm voters

President Donald Trump's State of the Union address on Tuesday is likely to be a test run of the message Republicans will give to voters in November's elections for control of the House and the Senate.

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Feb 23 • 8:10 PM EST • Politics • pbs.org
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The Beclowning of Scott Bessent

One iron law of current politics is that nobody who associates themselves with Donald Trump emerges with a shred of credibility. For some, that’s not a big loss — it’s not as if anyone respected Pete Hegseth even before he decided that the key to military success in an age of drones and AI was more testosterone. For others, however, the costs are real. I’m old enough to remember when Marco Rubio was widely considered a reasonable, thoughtful politician. Right now, however, my candidate for the biggest loser is Scott Bessent, the Secretary of the Treasury. Bessent started out with significant reputation to lose: When Trump selected him, this was the headline in the Financial Times: Jason Furman, Barack Obama’s chief economist, described him as a “credible Treasury secretary who has a real understanding of the global economy”. But Bessent has now transformed himself into the Baghdad Bob of bonds. Three weeks ago, after intervening (for reasons that remain somewhat unclear) to support the Japanese yen, Bessent boasted about his ability to move markets and dared investors to bet against his, declaring “I am the house now.” He then tried to push long-term interest rates down, buying 30-year U.S. Treasuries in a move some have compared to paying down part of your mortgage by running up your credit card balance. Here’s how that’s going so far: To get some perspective on how high interest rates have gone, here’s a longer-term perspective: We haven’t seen interest rates this high since the fading days of the dotcom bubble. Why are interest rates hitting new records? The backdrop, as I argued in last Sunday’s primer, is the huge AI-driven investment boom; more on that next week. But the immediate cause of the latest interest rate spike was Trump’s rejection of an Iranian proposal to end the war. This rejection sent crude oil prices, which for a while had fallen considerably, shooting back up: It’s notable, by the way, that oil prices remain high even though a significant amount of oil is now being shuttled through the Strait of Hormuz by night, on smaller vessels. That’s an interesting story, which has a lot to do with the fact that oil from the Hormuz shuttle runs must be transferred to larger vessels before being shipped to markets in Europe and Asia; around 15 percent of the world’s large crude carriers are now parked off the coast of Oman, waiting to be tanked up. This is creating a shipping crunch: But that’s a topic for another day. For now, the point is that with oil still high and refined products, especially diesel, still close to record levels, inflation will remain elevated. And this in turn means that the Federal Reserve will keep short-term interest rates high, an expectation that is feeding into longer-term rates. Hence Bessent’s bond-market humiliation. The truth is that Bessent might not have been able to get interest rates down even in the best of circumstances. But he certainly won’t get anywhere as long as Trump keeps believing that he can somehow convert his Iran debacle into a triumphant victory. And Trump will keep believing that as long as he is surrounded by sycophants who tell him what he wants to hear. Sycophants like, for example, Scott Bessent, who is predicting the imminent collapse of the Iranian economy, possibly within two weeks. Bessent is right to say that the embargo on Iranian oil exports is placing the country under great economic strain. But his implicit prediction that this will quickly produce a deal that Trump can call victory looks no more plausible than his boasts about the bond market. The big question now is, why would anyone with a reputation to lose work for Donald Trump? As the beclowning of Bessent shows, joining the Trump team won’t just damage your reputation; it will utterly destroy it.

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Sep 29 • 7:10 AM EDT • Politics • paulkrugman.substack.com
Major Marvel reunion spotted on 'Daredevil: Born Again' season 3 set

'Daredevil: Born Again' season 3 will be a major Marvel reunion. Set photos spoil juicy new casting additions.

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Apr 3 • 9:36 PM EDT • Entertainment • ew.com
New Jersey senator dares DHS to pepper-spray him again as Mullin slams 'political theater'

Sen. Andy Kim and DHS Secretary Mullin trade accusations over chaotic protests and pepper-ball spray incident at Newark's Delaney Hall facility.

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May 28 • 3:10 PM EDT • Politics • foxnews.com
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Virginia Dare expands sensory and health & wellness teams

The US flavour specialist will showcase functional food, beverage and supplement concepts at SupplySide Global, highlighting its expanded capabilities in sensory testing, formulation and wellness-focused product development

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Oct 12 • 11:13 AM EDT • Health • nutraceuticalbusinessreview.com
Jessica Jones first look in 'Daredevil: Born Again' previews war for New York (exclusive)

'Daredevil: Born Again' season 2 first look reveals Krysten Ritter's Jessica Jones, Matthew Lillard's Mr. Charles, and more players in the war for New York City.

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Dec 18, 2025 • 12:00 PM EST • Entertainment • ew.com
Children's Wisconsin, UW Health under pressure to resume care for transgender youth

More than 60 advocacy organizations and businesses in Wisconsin are calling on the state's top children's hospitals to resume providing gender-affirming care for transgender youth.

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May 21 • 5:15 PM EDT • Health • wpr.org
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Germany’s Political Tailspin: Your Weekly SPIEGEL Recap

It might be tempting to dismiss the results of last Sunday’s state election in Saxony-Anhalt, in which the far-right Alternative for Germany (AfD) party raked in 43.8 percent of the vote, as a rather unimportant extremist blip in a state that hardly anyone can find on the map. And you wouldn’t necessarily be wrong to do so. The state’s population – around 2.1 million – is a mere 2.5 percent of the German total. And while the state capital of Magdeburg was once the political heart of the Holy Roman Empire back when Otto the Great used to hang out there (more than a millenium … no … milennium … nope … millennium ago), it is today something of a backwater, albeit one with a ginormous cathedral in its center. We wanted to briefly interrupt this week’s newsletter to extend a heartfelt thank you to all of our subscribers, both new and old. And to remind you all that a free subscription gets you access to this newsletter every Saturday. A paid subscription, by contrast, gets you one DER SPIEGEL article every weekday, delivered to your inbox. We strive to select pieces that both demonstrate what Europe’s leading newsmagazine has to offer and provide an international audience – namely, you – with an insight into how Germany and Europe view the world. If you haven’t already signed up for a paid subscription, please consider doing so if you can. Our Substack channel relies entirely on reader support and we are excited to continue offering you the best of DER SPIEGEL. Subscribe But even beyond the fact that a huge percentage of the voters in the state decided to place an X next to a party with an ideological lineage that runs rather directly back to the right-wing extremist soup out of which the Nazi Party was born, the results are a perfect example of a phenomenon that has been plaguing German elections in recent years: the lack of an obvious path to a majority. Call it the Balkanization of German politics. There are a number of developments driving the phenomenon, but for the purposes of this newsletter, here are two of the most salient: Persistent voter frustration with the country’s two (former) big-tent parties – the Christian Democrats (CDU) on the center-right (17.2 percent in Saxony-Anhalt last Sunday) and the Social Democrats (SPD) on the center-left (9.3 percent). The presence of parties on the far left (Left Party), the populist left (the Sahra Wagenknecht Alliance – BSW) and the far right (AfD) with which mainstream parties are reluctant to form coalitions. So what happens now? Stories of the Week A Lack of Leadership The answer for many people in the country, and particularly within the CDU, is clear: pin (some of) the blame on Chancellor Friedrich Merz. According to a survey taken directly after the election in Saxony-Anhalt, 88 percent of respondents agreed with the statement that if the federal government in Berlin were doing a better job, the AfD wouldn’t be as strong. And it is true that the predominant impression of the federal government ever since Merz was sworn in on May 6, 2025, is one of ineffectiveness and bickering. His rather unique combination of bumbling-plus-bravado has also not exactly endeared him to the German public. Indeed, his standing in the country is so shaky that his popularity – according to recent polls – has now dropped even below the historic lows associated with his predecessor Olaf Scholz. The situation is such that the CDU even opted to keep him largely out of the campaign ahead of the Saxony-Anhalt vote. And since then, dissatisfied rumblings within the CDU have grown louder. DER SPIEGEL’s Swantje Karich notes that the problems with the CDU go much deeper than Merz. “The center-right has a trust problem. At a press appearance following the devastating election result in Saxony-Anhalt, Friedrich Merz said that the party wanted to ‘reach people more effectively’ through ‘emotional engagement.’ It sounded as though he were announcing a political program. On the basis of that statement, it is difficult to take his empathy seriously.” “The Chancellor’s chastened appearance did, at least, reveal where he stands: with his back to the wall. Elections will be held in Mecklenburg-Western Pomerania next week, and the CDU could fare even worse there. The party is polling at between 8 and 10 percent in the state.” “What is at stake is the political tradition that has lent stability to the Federal Republic since 1945: a democratic conservatism that understands what must be preserved, but also how to embrace progress and openness to the world. If the Union continues along its current path, it risks becoming politically irrelevant after the 2029 federal election – and Germany could soon find itself with a government of the far right.” The Trumpification of Political Debate? It is often said in Germany that to understand the political and social trends that will soon be dominant in Europe, one need only look across the Atlantic to the United States. When it comes to political debate, that has certainly proven true. Donald Trump understood early on that triggering mouth-foaming outrage among Democrats is an ideal way to both generate headlines and to secure loyalty among supporters. And he realized that far more quickly than the left side of the political spectrum understood that simply ignoring the old man might be the best recipe. To be sure, there have been signs recently that the US president may be over-relying on the strategy. Earlier this week, in an apparent grandpa-discovers-AI moment, Trump sent out 60 posts in the space of 10 hours, many of them AI-assisted images portraying him as a hero – or showing Iceland as part of the US (outrageous!!!). It was also during that slew of schlock that he explicitly backed the AfD with an “MGGA” post. In Germany, though, the outrage cycle remains in full swing, with much of the focus on those who would dare to vote for the AfD. They are alternately portrayed as being dim-witted, ungrateful, backward, racist or all of the above. That, argues DER SPIEGEL columnist Sabine Rennefanz, is not particularly helpful. “Everywhere on election night, people spoke of a watershed moment, a rupture, a turning point. But what is that supposed to mean in concrete terms? A watershed would imply an interruption, a moment of pause – perhaps even a willingness to rethink and learn. At first, there was little sign of that in the main television panels. Instead, the familiar rituals that had already shaped the election campaign continued: outrage, lecturing and abuse.” “That’s just the tone, one might object. They’re only talk shows. Given that the party’s state branch has been classified by domestic intelligence officials as confirmed right-wing extremist, there are more important problems than hurt feelings on television. Yet although the condescending tone is not the cause of the AfD’s success, it is an expression of the broader mood within the so-called political center – a kind of institutional blindness that too often treats material concerns as a communications problem.” “People have a pretty good sense of whether you like them – whether you approach them with curiosity or merely study, lecture and manage them as a problem group. They notice whether you genuinely want to understand their fears and pain, or whether you are simply waiting for the chance to correct them. They can also tell whether someone still has the energy to change things, or whether they have barricaded themselves behind platitudes and empty phrases.” “Anyone who wants an egalitarian democratic society cannot promise equality only to those whose language, tastes and moral convictions they share. They must also acknowledge the wounds, resentments and fears of those whose political conclusions they consider wrong. Acknowledging them does not mean agreeing with them. But a democracy that communicates with almost half its citizens only through warnings and labels gives up on political debate before it has even begun. An atmosphere must be created in which people can express their opinions without fearing that they will be canceled. We are currently a long way from that.” East-West? One of the clear undercurrents in the election last Sunday was, of course, Germany’s ongoing east-west divide, particularly as it pertains to the success of the AfD. Historically, the party has been far stronger in the former East German states than in former West German states. The fact that this generalization no longer reliably holds is certainly one of the primary concerns that many have about the party’s growth. And yet, there is still a distinct flavor of “stupid easterners, they don’t understand democracy” to the coverage. In the weeks before the vote, there was even a rather interesting back-and-forth in Germany’s culture pages about how ungrateful eastern Germans allegedly are for being pulled out of their pre-reunification backwardness and into the light of the West. DER SPIEGEL’s Jochen-Martin Gutsch has had enough. “Ten years ago, in 2016, elections were also held in Saxony-Anhalt. The AfD won more than 20 percent, which at the time rightly provoked outrage and incomprehension in western Germany. Today, in 2026, the AfD is also polling at around 20 percent in western German states, but this no longer provokes outrage and incomprehension. Instead, it is now regarded as proof of democratic conviction and civilizational resistance. After all, in the east, it’s 40 percent!” “This allows people to continue feeling morally superior to the East, but the wiser course would be to admit: if something doesn’t happen soon, the West will turn AfD-blue too. Or bluish.” “But will anything happen? The truly depressing thing about election night was not so much the AfD leaders intoxicated by their own success. It was the representatives of the other parties, who once again said that they were utterly shocked, needed some time to digest the result and would, of course, not simply return to business as usual. The SPD, a former big-tent party, celebrated its ‘stable’ result of 9.3 percent. Congratulations!” “For 10 years, the AfD has gone from one electoral success to the next. And still, the established parties remain ‘shocked’ and scratch their heads in astonishment. How long can they keep being shocked? Friedrich Merz says he may need to communicate his reform ideas in a more ‘emotional’ way. So the CDU’s political professionals sit down together after the election, mull over a strategy, and in the end come up with this: Fritz, try to be a little more relaxed, charismatic and emotional – or something. Beyond that: no political plan, no defiance, no promise of a future. That is frightening.” What was good, what was bad for democracy? Good: Voter turnout in Saxony-Anhalt was 77.8 percent, the highest ever recorded in the state. Whatever one thinks of the result, that figure is encouraging. Democracy needs citizens to take an interest. Bad: Although a strong AfD result had been expected in Saxony-Anhalt, many politicians from the mainstream parties – including in Berlin – appeared confused, helpless and overwhelmed in their initial reactions. That is not how they will win back voters’ trust. Last Week’s Highlights: 🗳️ Meet the Germans Who Voted for the AfD: Why would voters in a country like Germany, with its Nazi past, vote for a right-wing party? It’s a question only an editor in Berlin could come up with. On the ground, the view is different. 🟦 How the AfD Wants to Expand Its Power Across Germany: The far-right AfD is planning to decimate public broadcasting in Saxony-Anhalt, revamp education and install extremists in positions of power. And it is eyeing victory on the national stage as well. 🕯️ The Continuing Reverberations of September 11: It was a generational shock, and the consequences can still be felt today - from massive surveillance and significant increases in presidential power to violent excesses at ICE. 🤝 “For Europe, Canada Is the Preferred Partner in Trans-Atlantic Relations”: In an interview with DER SPIEGEL, Canadian Finance Minister François-Philippe Champagne discusses his country’s failed trade deal with the US and why Canada is looking to Europe. 🏛️ The True Historical Roots of the AfD: During the Weimar Republic in the 1920s, there were numerous parties on the extreme right espousing “Germany first” nationalism. The Nazis may not be the best comparison for today’s AfD. 🌊 AfD in a Landslide: Merz Is the Wrong Leader for Germany: The right-wing Alternative for Germany won in a landslide in Saxony-Anhalt state elections on Sunday. What does that mean for the country at large? Thank you for your continued support and have a wonderful week! Subscribe Share Leave a comment Your SPIEGEL Substack Team Compiled and edited by Charles Hawley

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Sep 12 • 7:49 AM EDT • Politics • derspiegel.substack.com
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To Comment or Not to Comment: Stars Wrestle With Politics on Red Carpet

It used to be that celebrities landed in hot water when they dared speak out about politics. Nowadays, they're getting slammed when they don't.

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Mar 27 • 11:30 AM EDT • Politics • hollywoodreporter.com
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Children's Wisconsin, UW Health stop providing gender-affirming treatments for minors

Children’s Wisconsin and UW Health have stopped providing gender-affirming care treatments to minors, citing recent federal policy changes.

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Jan 12 • 6:42 PM EST • Health • wpr.org
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Vincent D'Onofrio Shuts Down God Of War Laufey Gooner Complaints: 'Buddy Got Bodied By Kingpin'

The Daredevil costar has no time for unhinged gamer conspiracies

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Sep 30 • 3:15 PM EDT • Technology • kotaku.com
‘Daredevil: Born Again’ ending with season 3 amid showrunner departure

‘Daredevil: Born Again’ will end with the upcoming season 3 as Marvel parts ways with showrunner Dario Scardapane.

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Sep 21 • 4:49 PM EDT • Entertainment • ew.com
Why Do Humans Look So Different From Each Other? Because Our Faces Evolved To Be Unique

In an age of filters washing us into uniformity, dare to have a little something something.

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Mar 27 • 11:56 AM EDT • Science • iflscience.com
Texans sign Dare Ogunbowale from Raiders practice squad

Dare Ogunbowale is heading to a new team after being signed off the Raiders practice squad.

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Sep 29 • 4:49 PM EDT • Sports • sports.yahoo.com
Black Women Political Candidates Are Expected to Be 'Likable,' Qualified and Tireless. Men Aren’t.

What I had experienced during that run wasn’t entirely unfamiliar to me. The year before, in 2013, I had run for president of the Young Democrats of America (YDA), a national political party office role, against a popular opponent. The opponent was a Black man, so race wasn’t a factor in the election; however, gender was. Before my campaign, I was vice president of YDA and had heard only good things about my service: my fundraising efforts, the partnerships I had engineered with progressive organizations, and programming coordination for the membership. However, when I decided to run for president, I instantly became ‘difficult to work with’ and ‘mean.’ Research on women candidates confirms that voters are less likely to vote for a woman if they don’t like her; by comparison, voters don’t need to like men to elect them. But when I was running as the Black woman candidate in a seven-candidate primary for public office, with two other women in the race, I noticed almost nothing about my being ‘difficult’ and more about my ability and work ethic. My experience running for public office reflected the systemic bias and double standards not just for women candidates, but Black women candidates who dare to aspire to any sort of political leadership—and that needed to change. We need more progressive Black women in public office for a myriad reasons, but we also specifically need the younger generation of Instigators in office, candidates who understand the times in which we live currently. Electing more Black women will take real investment in changing the biases and attitudes (conscious and unconscious) of mostly white donors, media, campaign staff, consultants and institutional leaders to help shift the culture and systems. But this support needs to be substantively increased so that we can rebuild an inclusive, multiracial democracy with the leaders we want and need. (Excerpted from The Instigators: How Black Women Have Been Essential to American Democracy by Atima Omara.)

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May 28 • 10:23 AM EDT • Politics • msmagazine.com
Marc Summers details the only episode of ‘Double Dare’ that never aired

‘Double Dare’ host Marc Summers recounts getting ‘physically sick’ after a kid got seriously injured while competing on the Nickelodeon game show.

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Jul 27 • 5:00 PM EDT • Entertainment • ew.com
The 98 Biggest TV Show Flops, Bombs and Misses in the First Half of 2026

(Welcome to the Entertainment Strategy Guy, a newsletter on the entertainment industry and business strategy. I write a weekly Streaming Ratings Report and a bi-weekly strategy column, along with occasional deep dives into other topics, like today’s article. Please subscribe.) In July, I updated my look at how the “streaming bubble” popped since 2023, showing the decline in streaming TV shows over time. But after compiling and analyzing and writing about over one hundred TV show flops in the first half of 2026—I counted 99 “nominees” and there are even more honorable mentions—I couldn’t have told you that the number of shows is going down. When it comes to scripted, English-language TV shows, it feels like we have as many bombs as ever. I don’t keep a specific count, but some streamers probably had as many flops as they’ve ever had.1 That’s right, it’s time for part two of my analysis of the biggest flops, bombs and misses on streaming in the first half of 2026. Two weeks ago, I took a look at films. Today, TV shows. If you want to read the full methodology for how I assemble this list, you can find it at the bottom of this article. In short, this list is… ...scripted and unscripted TV shows,...from the nine major streamers,...in the US (using US-only ratings),...excluding true crime, kids and foreign-language shows,...that got no/poor ratings,...from Jan-2026 to the end of June-2026. Reminder: this article does not represent my personal opinion—many of these shows are great!—but I follow the data, and a miss is a miss and a bomb is a bomb. Also, price matters. If a TV show costs north of $100 million, it needs to get lots and lots of streaming viewership to justify that budget. As with past editions, I ordered this list by streamer, going from best (fewest flops) to worst (the most misses)—taking the size of the flops into consideration—and like the last edition, three or four streamers vied to take the win/loss of having the most flops. (But the actual winner is no surprise.) I try to avoid tooting my own horn too much, but seriously, in just under 5,000 words (including the methodology section) I provide a mostly comprehensive overview of the eight major streamers (Netflix, Disney+, Prime Video, Hulu, HBO Max, Peacock, Paramount+, and Apple TV) for the first half of the year, mentioning most of their hits and all their misses. It summarizes the entire first half of 2026! If you want to support this work, please subscribe. Subscribe Tubi Big Mood Boarders The Freak Brothers Twenty Twenty Six Honorable Mentions: Busted on Bodycam, Deestroying the Pitch, Destination World Cup 2026 I don’t think that Tubi spends all that much making or (mostly) licensing these original TV shows—Big Mood, Boarders and Twenty Twenty Six all come from the UK—but they’re not free and they didn’t chart anywhere. Winner: The Freak Brothers Have you even heard of this show? It’s an animated comedy...that’s on its third season! And Pete Davidson, Woody Harrelson, John Goodman and Tiffany Haddish all provide voice talent for it. Yes, animated shows don’t cost as much as live action shows, but cheap isn’t free! So a show with this level of talent needs to perform better. Disney+ Daredevil: Born Again Star Wars: Maul – Shadow Lord Honorable Mentions: Behind the Attraction, Donna Hay Coastal Celebrations, We Call It Imagineering Disney+ doesn’t make all that many original shows anymore. They had two flops, and one was animated. Their one not-a-miss show, Wonder Man, got just good enough viewership to not be considered a “miss”...but it’s since been cancelled. At this point, Disney has pivoted entirely away from making big budget TV shows for Disney+ to making...almost nothing for Disney+? Sure, Disney’s spending circa 2019-2022 was unsustainable, but now they’re pivoting too far in the other direction. At some point, Disney needs to stop shifting strategies so wildly. Really, Disney should have made fewer shows for Disney+ at launch and the shows they did make at that time needed to be made at more reasonable budgets. And they should adopt that strategy now. Winner: Daredevil: Born Again Daredevil, the Marvel Comics character, is on my personal Mount Rushmore of favorite superheroes, so it pains me to give him the win/loss today, but this show deserves it. I’ll repeat my hot take from last spring: “Based on his popularity, Daredevil should be in movies, and probably ones that cost a lot less than the MCU’s usual price tag. Disney/Bob Iger/Ike Perlmutter (who, based on reporting, made the decision) made a huge mistake selling TV shows to Netflix in the 2010s, thus limiting this character to the small screen. Daredevil could have anchored Marvel’s post-Infinity War plans, and if he did, the MCU would probably be in a better place than it is now.” HBO Max We’re just getting started with this issue, but the rest is for paid subscribers of the Entertainment Strategy Guy, so if you’d like to find out… What four streamers had the most misses... HBO’s strong start to 2026… The caveat to Peacock’s turnaround this year... Paramount+’s key man problem… What country isn’t delivering hits for Netflix or Hulu... The cavalcade of stars on a streamer where no one is watching their shows... Across nearly 5,000 words of analysis… And a lot more... ...please subscribe! We can only keep doing this great work with your support. If you’d like to read more about why you should subscribe, please read this article about the Streaming Ratings Report, why it matters, why you need it, and why we cover streaming ratings best.

Remembering designer Bob Mackie and his impact on American culture [Unscripted column]

When I was a tween and then a teen in the late 1960s and into the ’70s, I wouldn’t dare miss “The Sonny & Cher Comedy Hour” or “The Carol

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Sep 19 • 5:00 AM EDT • Entertainment • lancasteronline.com
‘Brave from the beginning’: 20 years of Friday Night Lights – the sports drama that dared to be different

It launched the careers of Jesse Plemons and Michael B Drama, and let its stars improvise in a way that was fresh and new. This show about smalltown US football was confident, trailblazing – and wonderful

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Oct 3 • 7:00 AM EDT • Sports • theguardian.com
God of War Laufey Star Deborah Ann Woll Breaks Silence on a Massive 10-Year Secret: “I Still Pinch Myself”

Renowned actress Deborah Ann Woll, best known as Jessica Hamby in True Blood and Karen Page in Daredevil, has spoken with CGMagazine about her lead role in God of War Laufey as the titular character. In an interview conducted during Game Con Canada, Woll confirmed what Game Director Ariel Lawrence had revealed earlier this month: Head of Creative Cory Barlog had this game in mind even before the launch of God of War 2018, and there was already a poster featuring Laufey and Phranque (the cosmic cube). Related Story Unlocking the Snapdragon 8 Elite Gen 6 Pro’s Real Performance Will […]

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Jun 22 • 9:00 AM EDT • Technology • wccftech.com
'Look at me!' Justice fires back at critics who dare question his Blackness

Supreme Court Justice Clarence Thomas reveals how Thomas Sowell's work freed him from isolation and gave him confidence to challenge Black political norms.

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Aug 13 • 2:34 PM EDT • Politics • foxnews.com
Denton teen’s mental health nonprofit partners with UNT to expand support for young people

At 17, Ajim Tubuo is using his own experiences with anxiety and depression to help other young people find support. His nonprofit, Dare to Live, partnered with the UNT Psychology

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Oct 8 • 8:00 PM EDT • Health • dentonrc.com
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“Survivor” winner Dee Valladares officially revealed as final “Big Brother” season 28 player

The reality TV champ was unveiled on “Big Brother: Unlocked”

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Jul 10 • 8:06 PM EDT • Entertainment • yahoo.com
Everything announced at Marvel TV's New York Comic Con panel

From "VisionQuest" to "Daredevil: Born Again" Season 3, here's what we learned and saw.

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Oct 8 • 6:20 PM EDT • Entertainment • mashable.com
6 executives share the books that shaped their leadership

Executives highlighted leadership staples like "Dare to Lead," as well as titles focused on soft skills, like "Emotional Intelligence."

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Dec 3, 2025 • 5:24 AM EST • Business • businessinsider.com
‘Daredevil: Born Again’ Season 2 review: Balancing the scales of justice

Season 2, which premieres Tuesday on Disney+, is a greatly entertaining blend of crunchy action and compelling narrative, writes our reviewer.

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Mar 24 • 9:00 PM EDT • Entertainment • yakimaherald.com
Downtown Seattle hosts demonic supernatural casino show this month

Head to downtown Seattle this month, if you dare, to wager more than money at "ALL IN," an interactive theater-ish experience from Curious Levity.

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Aug 14 • 1:00 PM EDT • Entertainment • yakimaherald.com
We dream, we dare, we decouple — how Colorado turns values into policy

By Kathy White Gov. Jared Polis’ final State of the State address was a clear victory lap. After eight years as governor, he used the moment to highlight accomplishments, reflect on progress and remind Coloradans what his administration has delivered. That is understandable. There is a real record to point to, and much of it […]

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Jan 22 • 2:45 AM EST • Politics • coloradopolitics.com
‘Daredevil: Born Again’ weekly releases prove successful

You could say that Daredevil and I go way back. When I started reading comic books in middle school, “Daredevil” is where I started. I watched the original “Daredevil” series

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May 4 • 1:00 AM EDT • Entertainment • valpotorch.com
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Charlie Cox Reveals He's Already Recorded 40 Hours Of Lines For A Surprise Sega Game

The Daredevil and Clair Obscur actor confirmed the new voice acting work during his appearance at NYCC

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Oct 9 • 11:00 AM EDT • Technology • kotaku.com
Aberdare woman swaps personal trainer for AI ahead of half marathon

Could AI be changing the fitness industry by offering a cheaper alternative to personal trainers?

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Jan 2 • 1:11 AM EST • Technology • bbc.com
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Commentary: Politicians continue campaign of dehumanizing trans people as affordability crisis crushes families

Forget about the disastrous war nobody wanted, or your wallet drained by crippling expenses. Instead, be afraid of a small, defenseless community the GOP has scapegoated and reject as extremist any candidate who dares acknowledge their humanity.

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Sep 24 • 3:35 AM EDT • Politics • ohiocapitaljournal.com
Local couple makes business trimming cow hoofs

For Bonnie and Mike Strowd, the local couple tackles a job most wouldn't dare. Instead the two have built a business around it.

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Jun 22 • 5:11 PM EDT • Business • wral.com
Week 6: Texas high school football scores & highlights

DAINGERFIELD 35, HOOKS 70 BECKVILLE 42, WASKOM 13 JACKSONVILLE 24, KILGORE 42 TENAHA 28, OVERTON 70 PEWITT 56, UNION GROVE 22 QUEEN CITY 34, REDWATER 50 PINE TREE 42, PALESTINE 10 Plays of the Week OTHER SCORES: NEW BOSTON 35, HUGHES SPRINGS 33 HARLETON 35, ORE CITY 15 LINDEN-KILDARE 28, MERRYVILLE 36 (THURSDAY) MT VERNON […]

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Oct 3 • 1:14 AM EDT • Sports • sports.yahoo.com
Dare County workshop seeks stronger links between behavioral health and justice systems

Dare County community stakeholders, local law enforcement, and members of the local court system will come together Thursday and Friday, Oct. 8-9, to develop integrated strategies to effectively identify and […]

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Oct 6 • 7:45 AM EDT • Health • islandfreepress.org
Microsoft finally reveals Fable in full — A new quality bar for Xbox

Playground Games "Fable" is the first RPG from the iconic racing game studio, and dare I say it, it seems like the studio absolutely cooked.

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Jan 22 • 2:19 PM EST • Technology • windowscentral.com
Former Lions WR, Pro Bowler reportedly lands with 49ers

KhaDarel Hodge, who spent the 2021 season in Detroit, is headed to San Francisco after earning Pro Bowl honors as a special teamer with Atlanta.

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Aug 5 • 12:29 PM EDT • Sports • sports.yahoo.com
We Asked 5 Executives How They Add Leisure to Business Trips—and They All Said the Same Thing

Here’s how seasoned executives turn business travel into something more meaningful and, dare we say, fun, and it's simple and free.

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Mar 5 • 7:00 AM EST • Business • travelandleisure.com
Postpartum politics: What it means to run for government as a new mum

Victorian Greens candidates Nina Crawley and Lini Fernando reflect on their experiences running a political campaign just months after giving birth. From the challenges and compromises to the support networks that wrapped around them, and why showing up vulnerably in public space matters. Subscribe In 2024, when my second child was four months old, I decided to run for local government. Fast forward two years, I am again four months postpartum, with my third child, and this time running in the state election. But this time has hit differently. Going through pregnancy, birth and postpartum while being a political candidate has had a more profound and personal impact than I ever expected. I reached out to my fellow Greens candidate for the state election, Lini Fernando, who gave birth 20 days before me, and her experience closely mirrored mine. Postpartum has its own unique challenges that we’ve not seen reflected in stories about women running for office. When people discuss the “juggle”, they’re usually talking about the practical mechanics of looking after small children - childcare arrangements, pumping schedules and logistics. As mums of multiple children, we were both aware of the logistical changes and difficulties that accompany giving birth and the months after. We assumed that combining this with running for election would be hard, but that we could organise our way out of any problems. What neither of us anticipated was the intense vulnerability that comes with putting yourself into the spotlight of a state election campaign at a time when you are physically exhausted and navigating things like breastfeeding and feeling like a stranger in your own body. There have been challenges that neither of us anticipated. Firstly, needing to buy new clothes because the supportive leggings that are a staple of the postpartum wardrobe weren’t going to cut it for community events. Lini held her first fundraiser - a trivia night - just three weeks postpartum. A business-casual wardrobe, several sizes bigger than pre-baby, was needed, and fast. As women, how we look is closely scrutinised, and the internalised fatphobia is loud. We are conditioned from our earliest days to believe that our appearance is tied to our worth, and taught how we are allowed to show up in public. Women who dare to put themselves into the spotlight also receive more abuse than their male counterparts, including criticism of their appearance. To stand in front of members of your community and try to convince them that you’re the best person to represent them in parliament is a challenge in and of itself. To do it with leaking breasts, a pelvic floor that could betray you at the first sign of a sneeze, a body that still feels unfamiliar, and with half your hair falling out (hello postpartum hair loss!) is another thing altogether. It requires courage, allowing yourself the grace to be vulnerable in public, and the belief that showing up, however imperfectly, matters. And the vulnerability isn’t just physical; it also includes factors like having to ask a campaign team to accommodate the realities of having a baby. Asking for help is hard, and it’s a skill that both new parents and hopeful political candidates need to become comfortable with. Parents understand the disappointment that comes when a call for help or connection is rebuffed, like a friend cancelling a much-needed coffee. That rejection is amplified for political candidates calling dozens of people each week. Many people don’t realise running for Parliament, when you aren’t the incumbent, is a volunteer role supported largely by other volunteers who have to squeeze volunteering in around their paid work. Calls need to be made and meetings held after work hours - usually during “witching hour” (5-8 pm), that special time of night when babies cry for no reason. I found that I was struggling to make these commitments, or having to tap out and ask for them to be rearranged. When I spoke to Lini, we realised that she had had a similar experience, this push-pull of being the candidate and wanting to show our faces at meetings and help recruit new volunteers at ‘calling parties’, but also being the only people who could settle our newborns. Sometimes we could merge the two worlds; Lini and I realised that we had both attended 7:30pm meetings online, sitting in a dark room, struggling though breastfeeding and settling our babies. Although we’re both committed to breaking the stigma around breastfeeding, it can be hard to keep your composure while trying to feed a young baby as they try to latch, spew and fuss. Ultimately, Lini and I agreed that showing up vulnerably in public space matters. Leaders should possess empathy and understanding for those who feel raw and in transition; from the dad who just got evicted to the teen who acquired a disability - anyone who feels they aren’t the version of themselves they expected right now. The patriarchy tries to tell us otherwise, but women shouldn’t have to wait until they’re ‘recovered’, no longer vulnerable, before they feel entitled to participate in public life. In fact, we could all benefit from our leaders being a little more vulnerable. *This piece was cowritten, but has been presented in the first person for the sake of style. About the authors Nina Crawley is former teacher and community organiser who now works in human rights and inequality advocacy for a non-profit. She’s a mother of three keen to get back to running as soon as her pelvic floor allows! She’s contesting the seat of Ivanhoe for the Greens in this year’s state election. Lini Fernando is a lawyer working in diverse areas of law including anti corruption and public law. She’s a mother of two and a gardening and good policy enthusiast. She is currently contesting the seat of Croydon for the Greens in this year’s state election. Thanks for reading Cheek Media Co. ! This post is public so feel free to share it. Share

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Sep 10 • 10:31 PM EDT • Politics • cheekmedia.substack.com
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Theatre Cedar Rapids offers Halloween scares with ‘Exorcist’

Directed by UNI's Matthew Weedman, this isn't just a horror show — it's a powerful story about faith, doubt, and saving a child in crisis. See it now in the intimate Grandon Studio Theatre — if you dare.

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Oct 13 • 7:00 AM EDT • Entertainment • thegazette.com
Nobel Prize in Economics, Wolf Prize, Blavatnik Awards, and More Accolades for Columbians

From science to engineering, writing to social sciences, here are the Columbians who received awards recently.

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Oct 15 • 8:00 AM EDT • Science • news.columbia.edu
Motorola just shipped the one hardware upgrade everyone wanted and Samsung was too afraid to touch

The Motorola Razr Fold does what Samsung wouldn't dare

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Mar 10 • 7:00 AM EDT • Technology • androidpolice.com
‘Dare I say TikTok is saving jazz’: Black Nile rewrites the L.A. jazz story for a new generation

Inglewood brothers Aaron and Lawrence Shaw, the jazz duo Black Nile, step into their biggest hometown spotlight yet, joining Erykah Badu and the Charles Gaines Collective at the Hollywood Bowl on Sept. 29.

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Sep 28 • 6:00 AM EDT • Entertainment • latimes.com
Charles Barkley dares ESPN to fire him after his controversial Cardi B joke during NBA Finals

Charles Barkley reacted to the controversy surrounding the joke he made about Cardi B during the NBA Finals.

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Jun 10 • 6:54 PM EDT • Entertainment • ew.com
49ers News: Welcome to the Bay, KhaDarel and Ogbo

Your daily San Francisco 49ers news for Thursday, August 6th, 2026

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Aug 6 • 4:57 AM EDT • Sports • sports.yahoo.com
Women’s UFC champion dares Jake Paul to try MMA

“Bullet” takes aim at Jake Paul

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Apr 8 • 11:00 AM EDT • Sports • sports.yahoo.com
Vincent D'Onofrio on that 'Daredevil: Born Again' cliffhanger

Vincent D'Onofrio talks that 'Daredevil: Born Again' episode 4 cliffhanger and what happens next. 'He becomes more of a loose canon,' the star says of Fisk.

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Apr 8 • 10:00 AM EDT • Entertainment • ew.com
Body Resurrects Cells Marked For Death, Solving a 50-Year Mystery

A burst of regeneration.

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Jan 12 • 7:00 AM EST • Science • sciencealert.com
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The 49ers have 2 new additions to Wednesday’s injury report

Add KhaDarel Hodge and Keion White to the list

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Sep 30 • 3:57 PM EDT • Sports • sports.yahoo.com
How To Build A Billion-Dollar Business Like Clockwork

Building a billion-dollar business starts as an audacious idea that someone dared to take seriously.

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Apr 24 • 7:00 AM EDT • Business • investors.com
‘Daredevil’ star Wai Ching Ho dies at 82

The film and television veteran was also known for her roles in “Hustlers,” “Iron Fist,” “Turning Red,” and “Awkwafina Is Nora from Queens.”

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Jul 12 • 8:26 PM EDT • Entertainment • yahoo.com
Column | Lucas Pinheiro Braathen dared to be who he is. He won gold because of it.

Brazil’s first Winter Olympic gold medalist has a message worth listening to after his victory in the men’s giant slalom.

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Feb 15 • 5:00 AM EST • Sports • washingtonpost.com
Roku May Help Fox Avoid Aggregeddon

(Welcome to the “Most Important Story of the Week”, my bi-weekly strategy column analyzing the most important (but often not buzziest) news story of the last two weeks. I’m the Entertainment Strategy Guy, a former streaming executive who now analyzes business strategy in the entertainment industry. Please subscribe.) Scrolling through links over the last week, I stumbled across this fun headline: Wow. Formula 1 (the sport, not the docu-series) is the perfect “dog not barking”. As a reminder, each week in my Streaming Ratings Report, I call out the shows that miss every viewership chart. I dub them “dogs not barking”—like the Sherlock Holmes mystery—because without any data, we forget they even exist. This is in contrast to something like, say, a film flop—cough The Mandalorian and Grogu cough—where even underperforming at the box office is widely discussed here, there and everywhere. In the US, Formula 1 is now in “no public viewership data, so not discussed” territory. After moving to Apple TV from its former home of ESPN, basically no one talks about it. Apple did publish an initial, unsourced, unsubstantiated, (dare I say unserious) datecdote claiming more folks are watching Formula 1 on Apple than ESPN, but we haven’t gotten any updates since. This stands in contrast to when the sport streamed on ESPN, and ESPN PR provided weekly viewership figures. Formula 1 was, at best, a niche sport in America—averaging 1.3 million viewers in the Big Data Plus era—but now it’s basically anonymous. (And yeah, after moving to Apple, I very, very, very much doubt its ratings increased.) Unfortunately, that story isn’t quite big enough to warrant a section in today’s “Most Important Story of the Week” column, but I wanted to call it out, because otherwise, no one else will! Certainly, no one will write articles about the silence/ratings decline, unlike when they wrote breathless articles connecting the rise in viewership to Netflix’s Drive to Survive, including Reuters just last month. (This is a topic I’ve tried to provide a moderate/nuanced/non-hyped take since 2022.) Anyway, on to this week’s issue. I was a bit worried I didn’t have a juicy topic, then the Murdochs went out and did their Murdoch thing: buying Roku. So that’s the story of the week, and it happens to touch on quite a few themes of the streaming wars and the disruption therein. I’ll cover that, plus why more consolidation in Hollywood media looks likely, more good news on the Hollywood labor front, whether we’ll see an uptick in production in Los Angeles, some Broadway and theme park news, cellphone prices going up in the third world (and possibly everywhere), and more. Subscribe Most Important Story of the Week - Another Big Media & Entertainment Merger The story of the week is clearly Fox is buying Roku for $22 billion. I read a lot of good strategy takes on why Fox bought this streaming TV device maker—and I’ll have mine below—but what fascinates me more is how this deal connects to quite a few themes of the streaming wars, linking to everything from the pace of M&A to “aggregeddon” to Netflix’s recent M&A actions/inactions to the shift to advertising from pure play streaming and more. The only topic I can’t really connect it to is my old theory, “never bet against Rupert Murdoch” because he isn’t the one who did this deal; his son Lachlan inked it. (Do I think he provided advice, even at his 95 years of age? Sure.) That plus I have one additional piece of strategy for all entertainment players, inspired by this deal. So let’s dive into all those topics, starting with why I like this deal. Roku is a Great M&A Buy

Daredevil Star Charlie Cox Confirms He's in an Unannounced Sega Game

Daredevil star Charlie Cox has confirmed that he is starring in another video game, this one for Sega.

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Oct 8 • 7:37 PM EDT • Technology • ign.com
What Could Brighton Achieve This Season?

A strong summer, a good start and some serious togetherness... Can Albion dare to dream?

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Oct 1 • 10:12 AM EDT • Sports • sports.yahoo.com
Tolu Arokodare To Start: Ajax Predicted XI Against NEC Nijmegen

After a lengthy international break, Ajax return to action on Saturday night against NEC Nijmegen.

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Oct 10 • 6:00 AM EDT • Sports • sports.yahoo.com
10 TV shows that dared to kill off their main character

From "Breaking Bad" to "Charmed," these shows didn't pull their punches when it came to doing away with their leads.

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Jun 2 • 7:27 PM EDT • Entertainment • yahoo.com
Propelled by locals, driven by angels

Film on El Jebel daredevil Shafer plays Isis on Friday

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Sep 24 • 6:30 PM EDT • Entertainment • aspendailynews.com
Valladares joins bipartisan coalition aiming to protect entertainment industry jobs

News release State Sen. Suzette Martinez Valladares, R-Acton, joined 38 of her legislative colleagues in sending a letter to Gov. Gavin Newsom, Senate President Pro Tempore Monique Limón, and Assembly Speaker Robert Rivas, urging them to protect […]

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Jul 24 • 8:34 PM EDT • Entertainment • signalscv.com
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The Making of the Music of Kirby Air Riders — Part 1 - News

Interviewees Masahiro Sakurai (middle) Director of Kirby Air Riders. Worked on the Kirby™ series, Super Smash Bros.™ series, Kid Icarus™: Uprising, and more. Noriyuki Iwadare (right) Composer. Best known works include the Grandia series, LUNAR serie…

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Mar 2 • 7:00 AM EST • Technology • nintendo.com
49ers news: SF trades with NFC South team for linebacker

With just a few weeks left before the new season, the San Francisco 49ers continue to tinker with their roster. Recently, the 49ers added tight end Khalil Dinkins, offensive lineman Doug Kramer Jr., and wide receiver KhaDarel Hodge. On Sunday, they acquired a veteran presence to shore up their defense. The 49ers pulled off a trade , sending running […] The post 49ers news: SF trades with NFC South team for linebacker appeared first on ClutchPoints.

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Aug 23 • 10:41 PM EDT • Sports • sports.yahoo.com
Raiders Sign Ex-Raiders RB to Replace Veteran

The Las Vegas Raiders decided to sign another veteran running back after Dare Ogunbowale got poached by the Houston Texans. The post Raiders Sign Ex-Raiders RB to Replace Veteran appeared first on HEAVY.

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Sep 30 • 3:53 PM EDT • Sports • sports.yahoo.com
I’ve Been in a Long, Abusive Affair With My Favorite Bedroom Appliance. I Finally Dared Ask What It’s Doing to Me.

Every morning I do it again, and again. Maybe that's OK.

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Apr 5 • 5:35 AM EDT • Health • slate.com
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‘Daredevil: Born Again’ stars preview Defenders reunion with final season teaser

Marvel’s ‘Daredevil: Born Again’ stars staged a Defenders reunion at New York Comic Con to preview the final season of the superhero show.

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Oct 8 • 5:06 PM EDT • Entertainment • ew.com
‘Don’t you dare count us out’: KC women’s sports mogul hails US rugby double-header

Kansas City Current soccer co-owner Angie Long played the oval-ball game at college. Now she’s hosting a crunch game between the Eagles and Australia

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Apr 17 • 6:00 AM EDT • Sports • theguardian.com
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Entertainment Look-A-Head: Michael Jackson movie release, Daredevil’s story continues, more games drop

From April 21 - 27, numerous video games launch alongside a wave of streaming content. Major shows like “Andor” and “The Boys” return and the awaited Michael Jackson movie arrives in theaters. The 2026 NFL Draft also begins on Thursday.

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Apr 20 • 8:00 PM EDT • Entertainment • thepostathens.com
‘How dare you!’ Panel debates judge blocking Trump’s $1.8B fund
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May 29 • 10:51 PM EDT • Politics • cnn.com
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'Daredevil: Born Again' season 2 finale's surprise reveal confirms Marvel casting

The 'Daredevil: Born Again' season 2 finale comes with a surprise character reveal with big implications for season 3.

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May 5 • 10:05 PM EDT • Entertainment • ew.com
Business solutions company Conduent names Sundaresan chief information and technology officer

Conduent Inc. announced Sept. 14 the appointment of Narayanan Sundaresan as chief information and technology officer, effective immediately.

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Sep 15 • 7:36 AM EDT • Business • roi-nj.com
Opinion: If you’ve stopped talking with your political opposite, you’re missing out on a lot of fun

When’s the last time you had a conversation with your political opposite where you learned something and maybe even had fun? I dare you to try.

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Sep 21 • 6:00 AM EDT • Politics • yahoo.com
Week 6: Thursday high school football scores & highlights

Haughton 41, St. Fredericks 0 Haynesville 54, Glenbrook 36 Huntington 33, Byrd 28 BTW 26, Northwood 58 Linden-Kildare 14, James Bowie 56 Other scores: (LA) Lakeside 15, Mansfield 42 (LA) Bossier 0, North Webster 22 (LA) Loyola 46, Sterlington 66 (TX) Gladewater 46, Sabine 14 (TX) Overton 49, Cross Roads 22

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Oct 8 • 11:41 PM EDT • Sports • sports.yahoo.com
I’ve Been in a Long, Abusive Affair With My Favorite Bedroom Appliance. I Finally Dared Ask What It’s Doing to Me.

Every morning I do it again, and again. Maybe that's OK.

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Apr 5 • 5:35 AM EDT • Technology • slate.com
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AbCellera women’s health data top ‘most aggressive upside scenario,’ putting Astellas and Bayer on notice

AbCellera has reported phase 2 results “beyond even the most aggressive upside scenario” that its CEO dared to consider, boosting the biotech’s chances of challenging Astellas and Bayer for a women’s health market. The phase 2 clinical trial compared ABCL635, an antibody targeting NK3R, to placebo in patients with hot flashes caused by menopause. Investigators enrolled 92 postmenopausal women experiencing a mean of about 10 moderate or severe hot flashes per day. By Week 4, the number of moderate or severe hot flashes had fallen by a mean of 8.8 on ABCL635 and by 3.5 on placebo. That statistically significant, placebo-adjusted reduction of 5.3 hit the trial’s primary endpoint. The level of efficacy also cleared the bar set by existing drugs. While cross-trial comparisons can be misleading, AbCellera CEO Carl Hansen, Ph.D., had seen enough to start hyping the program. “We now view ABCL635 as a potential best-in-class non-hormonal therapy with strong differentiation against approved NK3R competitors across all important dimensions, including efficacy, safety, dosing and convenience,” Hansen said on a Monday morning conference call with investors to discuss the data. “We believe ABCL635 is now a highly de-risked program.” Last week, Hansen used AbCellera’s earnings call to set expectations for readout, with the CEO defining success as a clean safety profile and efficacy comparable to the two approved small molecules. The data vaulted over that bar. Astellas linked (PDF) one of the small molecules, Veozah, to placebo-adjusted reductions in hot flash frequency of 2.1 and 2.6 at Week 4 of its two phase 3 trials. Bayer reported (PDF) placebo-adjusted reductions of 3.04 and 3.29 at Week 4 of pivotal studies for its small molecule, Lynkuet. At 5.3, the placebo-adjusted reduction in AbCellera’s trial comfortably cleared the standard set by the incumbents. Veozah and Lynkuet came to market based on evidence of their ability to reduce the frequency and severity of hot flashes. AbCellera’s phase 2 study covered both endpoints, with the Canadian biotech reporting a mean reduction in severity of 1.4 points at Week 4 on ABCL635, compared to 0.3 points for placebo. Again, the placebo-adjusted result compares favorably to data on Veozah and Lynkuet. Analysts shared Hansen’s enthusiasm for the data. The phase 2 results “firmly validate ABCL635 as a potentially best-in-class treatment,” BMO Capital Markets analysts said in a note to investors Monday. ABCL635’s apparent efficacy edge “is likely attributable to the higher dosing/target engagement the asset is able to reach vs. the oral agents due to its wider therapeutic index,” the analysts added. The analysts, who model $2.3 billion in unadjusted peak sales for ABCL635, flagged the safety profile as another positive of the phase 2 readout. While Veozah carries a boxed warning for liver damage, nobody on ABCL635 in the phase 2 trial had elevated liver enzymes or bilirubin values. If replicated in phase 3, the lack of a liver signal could allow approval without the monitoring requirements imposed on Veozah. Investors appeared equally enthused, sending AbCellera's stock up 32% to $9.21 in premarket trading Monday from a Friday closing price of $6.93. Next, AbCellera will collect the Week 12 data and talk to its advisors about further development. The results open up “a wide variety of possibilities of how we might take this forward into phase 3 studies to truly maximize the value of the asset and make sure that ABCL635 is able to demonstrate its differentiation potential,” Sarah Noonberg, M.D., Ph.D., AbCellera’s chief medical officer, told investors.

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Aug 10 • 8:24 AM EDT • Health • fiercebiotech.com
Old iPods are making a comeback thanks to Gen Z

Now bring back the Microsoft Zune, I double dare you.

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Jun 18 • 9:30 AM EDT • Technology • engadget.com
Among the Academies: A Lifelong Fascination with Fish

For Peter Wainwright, the academic path was simple: he simply followed his fascination with fish."I dare say there wasn't a lot of deep thought about what direction I should go in my life," he said. "It was more, I like fish, let's see if I can do something with fish. It was all very organic."

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Sep 29 • 2:18 PM EDT • Science • biology.ucdavis.edu
Why has Venus obsessed so many astronomers?

Every 122 years, Venus crosses the Sun as a black and fleeting teardrop, kindling the awe of all those who dare to know

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Jul 17 • 6:00 AM EDT • Science • aeon.co
Does public health *need* MAHA?

Last week, our friend Dr. Craig Spencer sparked an ongoing volatile discussion with his Atlantic article “Public Health Needs MAHA.” Some have come out in strong dissent, others are cheering, and others are simply lamenting that we find ourselves in such a divided world to begin with. We will dare to dip our toes in these controversial waters, too. Does public health need MAHA? We think in some ways yes, and in other ways, no. MAHA leaders versus the everyday MAHA supporter The vitriol in this debate mostly comes from one collapsed distinction: the leadership of MAHA is not necessarily the same as the people who support it. Say “MAHA” and most people picture RFK Jr. Fair enough, as he coined the term and holds most of the power. And, yes, some MAHA followers treat Kennedy as something close to a saint. But talk to the grassroots, and it’s not a monolith. They’re Republicans, Democrats, and Independents. People who distrust vaccines and vaccine supporters. It’s a wide, eclectic coalition. The data backs this too: 4 in 10 Americans support the movement—that’s a lot of people! But according to polls, vaccines and medical choice (the issues most tied to Kennedy personally) are cited by only 4% as their reason for supporting the movement. For many, the motivations are much broader. Many MAHA supporters are signing up for the idea that “something needs to change” with health in this country. They’re asking good-faith questions about corporate influence on our health systems, health care costs, nutrition, chemicals, and clean air and water. These are all questions that plenty of public health professionals recognize as legitimate and also care about very deeply. Blurring the lines between the leadership and grassroots does real damage in two important ways: It hands the 4 in 10 exactly the narrative already fed—that the health ecosystem doesn’t listen, doesn’t care, and paints every critic with the same brush. It gives the actual bad actor more power. RFK Jr. has done irreparable damage and can’t be trusted. What the MAHA movement gets right A healthy population is something the public health field was literally built on, and many of these topics are things we have dedicated our lives to. Yet the MAHA movement has captivated nearly half the country in a way the public health establishment has failed to achieve. So that means MAHA is doing something right. Some of it may be timing (after a Covid-19 pandemic and deep frustration and mistrust with institutions). The movement also does three other things really well: 1. It gives a new, louder voice to system failures. While MAHA is not a monolith, one theme stays consistent across their stories: the system failed them. For some, it was the system that flooded their communities with opioids and then walked away. For others, it was the system that let their business collapse during Covid with no safety net in sight. For others still, it was the system that failed to help them manage a complex chronic illness, bouncing them from physician to physician without any real answers. And in many ways, our health ecosystems are failing Americans. Why are medical bills so incomprehensible? Why do some kids get a healthy school lunch and others don’t? Why do an epidemiologist and a MD/PhD student have to start newsletters in the middle of the biggest public health emergency in a century, just so people can get straight information? Because the systems failed. This deep-seated frustration driving many Americans to search for solutions elsewhere needs to be recognized. 2. MAHA has brilliant comms central to their efforts. MAHA figured out something most health institutions still have not: the information landscape changed. It’s participatory now, not top-down; influence runs through many nodes in a community, not one institution; and storytelling and telling audiences “what you really think” moves people more than data dumps do. MAHA goes where audiences are listening, using podcasts, social media, and memes in ways most health institutions would scoff at—but it works. 3. They are very good at organizing. A MAHA meeting feels like a rally: energy, speakers, music, and most importantly, an action for everyone. Someone’s writing the next policy brief, someone’s seeding a narrative, someone knows the next legislative deadline, someone’s sending the text messages for a campaign. None of this is new (ask the civil rights movement), but MAHA knows it works and has capitalized on it. What MAHA gets wrong This list could be much longer, and this newsletter has spent a lot of time covering it, but here are a few things: Poor use of scientific evidence. This is the fundamental problem with many MAHA policies: the hype outpaces the science, and experts are often villainized for pointing this out. MAHA leadership has traded real solutions for cheap wins. For example, instead of taking on the powerful food industry and passing real reforms, it has celebrated french fries made of beef tallow and taken out artificial dyes from still very sugary children’s cereal. These changes won’t move the needle on America’s diet. MAHA leadership has tried to dismantle vaccine access in the U.S. While many MAHA supporters emphasize other issues, the effort to change vaccine policy has become MAHA’s signature effort. This is not surprising given RFK Jr.’s extensive track record campaigning against vaccines. It has rallied behind the wrong leader. RFK Jr. has a decades-long track record of villifying doctors, scientists, and public health workers, well before he became HHS secretary. He is known for his decades-long work sowing distrust in vaccines as well as life-saving treatments like antiretroviral therapy for HIV. This is not a serious person who can move the needle on health in the U.S, and he has already done serious damage. Public health needs more than defense Defending the evidence is absolutely necessary so health in the U.S. doesn’t move further backward. The public health establishment is very good at defense. The problem is this defense often sounds like defending the status quo, which has failed many people. Public health needs to offer an alternative to RFK Jr.’s MAHA—one that is rooted in evidence, truly listens to and addresses people’s frustrations, and has innovative solutions and the courage to change the systems. How do we get there? Find common ground. Do you know what most people care most about? The abysmal cost of healthcare. Start there. Fight for the human loudly. Too often, communications and engagement center on science with a capital S, funding mechanisms, or the CDC/FDA/NIH. Not the person. So the public doesn’t see themselves in it. Instead, they see people fighting for the very powerful systems that they feel negatively impact their health and well-being. Let the public feel and hear that you see their frustrations, you get it, and you’re fighting for them within the system. Recognize when pro-science messages are alienating people. Facts absolutely matter, but angrily venting only alienates people further. Our friend Elisabeth Marnik recently wrote a New York Times article about her experience growing up unvaccinated and how listening and empathetic conversation are the only ways to reach people that really work (a position backed by communication science). Her comments section was full of hateful comments from pro-vaccine individuals attacking her for daring to suggest we approach vaccine-hesitant individuals with empathy. It is possible to both stand firm behind scientific evidence and empathize with people who don’t trust it. Lean into politics smartly. Often, public health has shied away from politics: Don’t touch it, lest you get burned. But this fails to recognize that the third rail is what fuels the train: who is elected determines our budgets, our priorities, and our authority. Being political means being very savvy in strategy on both sides of the aisle, knowing your audience, and recognizing that political capital is as scarce as financial resources and needs to be allocated accordingly. Bottom line So does public health need MAHA? That’s not really the right question. Public health has a responsibility not to dismiss 40% of the country who feel heard by this movement and are frustrated that the system has failed them. And it has a responsibility to stick to the evidence and recognize MAHA leadership for what it is: a danger to our nation’s health. Both can, and should, be done. Love, YLE and KP A big thanks to Craig Spencer, who had the courage to put his neck out there to start a much-needed discussion at such a critical moment—one that is determining the identity of an entire field. Kristen Panthagani, MD, PhD is completing an emergency medicine residency and research fellowship focusing on health literacy and communication. In her free time, she writes the newsletters You Can Know Things debunking health myths and rumors and The Public Health Roundup. Views expressed belong to KP, not her employer. Your Local Epidemiologist (YLE) comprises a team of experts, ranging from physicians to immunologists to epidemiologists to nutritionists, working together with one goal: to “translate” ever-evolving public health science so that people are well-equipped to make evidence-based decisions. The YLE suite of newsletters reaches over 475,000 people across more than 132 countries. This newsletter is free to everyone, thanks to the generous support of fellow YLE community members. To support the effort, subscribe or upgrade below: Subscribe

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