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Studying Science in an Anti-Scientific Time

This Chronicle Review Deep Cut was first published in 2025. By Julianne Werlin Thanks for reading The Chronicle Review! Subscribe for free to receive new posts and support my work. Subscribe The last two decades have not been kind to science studies. Already bruised and battered by the “science wars” of the 1990s, by the 2000s sociologists of science — who had long argued that science had to be understood in its human context — were encountering the funhouse-mirror version of their own views in right-wing critiques of climate scientists. It was enough to give some prominent scholars pause. “Was I wrong to participate in the invention of this field known as science studies?” asked Bruno Latour, the most famous sociologist of science in the world, in 2003. “Should we apologize for having been wrong all along? Or should we rather bring the sword of criticism to criticism itself and do a bit of soul-searching here: What were we really after when we were so intent on showing the social construction of scientific facts?” In response, Latour proposed a change of method and attitude. Science studies, now chastened and contrite, would no longer seek to strip facts of their authority, but to enrich and enhance them. What this meant in practice was never fully clear. But his diagnosis of problems resonated, even if his solutions did not. Latour’s exercise in public hand-wringing signaled a shift in mood. By 2016, with the first election of Donald Trump, the idea that skepticism of science was a right-wing position, not a left-wing one, had become a commonplace, discussed eagerly in The New York Times. For liberals, vaccine denial during the Covid era and Trump’s second-term attacks on the funding of scientific research, covered extensively in these pages, added a new urgency to the defense of science on both practical and principled grounds. There was little appetite for a sociology or philosophy of science that emphasized the messiness and missteps of the scientific process rather than its integrity and triumphs. The distinguished historian of science Peter Dear’s new book, The World as We Know It: From Natural Philosophy to Modern Science (Princeton University Press, 2025), which seeks to tell the story of 18th- and 19th-century science for a general public, may seem comfortably remote from these bitter contests. In its 16 short chapters, Dear draws swift, sure sketches of major discoveries from Newton to Einstein, ably guiding the reader through debates on stellar nebulae, animal taxonomy, atomic chemistry, evolution, and other flashpoints in the history of science. But though a work of history, Dear’s book must still negotiate our polarized present. In a blurb on its back cover, the historian of biology Lynn K. Nyhart alludes to the “present moment, when scientific knowledge is being swamped by misinformation and its institutions are under siege.” Dear himself, in his conclusion, refers to the “yard signs” and “bumper stickers” that proclaim “Science Is Real.” One antidote to both anti-science propaganda and to reductive slogans in science’s defense is a robust history and philosophy of science: exactly what Dear’s scholarship has long offered. But his new book illustrates how difficult such work has become. Dear, an emeritus professor of history at Cornell University, is best known as a creative and philosophically minded historian of the Scientific Revolution. His edited volume The Literary Structure of Scientific Argument (1991) analyzed the rhetoric of Galileo’s thought experiments to brilliant effect. Discipline and Experience: The Mathematical Way in the Scientific Revolution (1995) was a major contribution to the analysis of scientific experiments in early modern Europe and beyond, while Revolutionizing the Sciences: European Knowledge in Transition, 1500-1700 (2001), now in its third edition, remains one of the best overviews of the profound epistemological upheavals of 16th- and 17th-century science. But Dear has also ventured into later periods. Nearly two decades ago, in The Intelligibility of Nature: How Science Makes Sense of the World (2006), he turned to the 18th and 19th centuries to sketch a history and theory of scientific knowledge. Aimed at a generalist audience, Dear’s simple prose belied serious philosophical ambitions. Science, Dear argued, has two aspects: “natural philosophy,” the quest to understand the true nature of the universe, and “instrumentality,” the applied skills and technologies that allow us to manipulate the world for human advantage. Both strands are ancient, but the innovation of the phenomenon we call “science” was to yoke them together. As Francis Bacon wrote, “Human knowledge and human power meet in one; for where the cause is not known, the effect cannot be produced,” an insight typically abridged to “knowledge is power.” Or, in Bertrand Russell’s characteristically blunt phrase, science has two functions, “1. to enable us to know things, and 2., to enable us to do things.” So far, so conventional. But Dear took issue with this familiar story in one respect. Bacon’s formula implied that theory and practice could be fused in a single method. In fact, Dear argued, the quest to understand nature and the desire to manipulate it were coupled only loosely. They could come together, but they could also pull apart. Focusing on natural philosophy, the “knowing” half of the scientific circle, he used a series of case studies from cosmology, taxonomy, chemistry, electromagnetism, and quantum theory to show how theories changed over time, in dialogue with practice, but never reducible to it. Take the case of matter, the basic substrate of the physical world. In the 18th and 19th centuries, scientists not only disagreed about what it was, but also about how well it could be known. In 1789, the chemist Antoine Lavoisier dismissed speculation about the atomic composition of chemicals as “discussions entirely of a metaphysical nature,” as he sought to orient chemistry away from philosophical abstraction and toward laboratory results. But in the 19th century, atoms returned with a vengeance in the atomic chemistry of John Dalton, who wanted to explain the underlying structure of nature. It was not just that Dalton and Lavoisier had a different set of experimental results, or even a different theory, Dear showed. What counted as an explanation had changed. In arguing that scientific theories depended on their intelligibility to human beings with complex arrays of beliefs and commitments, Dear was in sympathy with science studies. Key figures such as the sociologist Steven Shapin emphasized the importance of psychological mechanisms like trust in the formation and acceptance of scientific ideas. But in focusing on the scientific pursuit of knowledge, not its politics or economics, Dear resisted the more cynical perspective of some of his colleagues. The Intelligibility of Nature strikes a very different note than Shapin’s collection of a few years later, Never Pure: Historical Studies of Science as If It Was Produced by People With Bodies, Situated in Time, Space, Culture, and Society, and Struggling for Credibility and Authority (2010), to name just one example. Walking a very fine line, Dear depicted science as driven at once by complex social dynamics and by the intellectual power of real discoveries. It was a testament not only to his own acumen but also to the vitality of the field that he was able to do so. Nearly two decades later, The World as We Know It returns to the questions broached in The Intelligibility of Nature. Like Dear’s earlier study, it begins with the Newtonian cosmos and ends with debates between Einstein and Bohr on quantum physics. Beyond its terminal figures, many of the same characters appear in both studies, including the naturalists John Ray and the Comte de Buffon; the chemists Étienne François Geoffroy, Antoine Lavoisier, and John Dalton; as well as Charles Darwin and Michael Faraday, among others. Its subject is nearly identical: As in The Intelligibility of Nature, The World as We Know It considers natural philosophy as opposed to instrumentality, here defined as the “desire to create a picture of what the world is really like — the world as God knows it — rather than simply having instrumental or operational control over it.” The two books also overlap in insights — and sometimes even in language. The reader who has learned in The Intelligibility of Nature that Buffon’s method of classifying animals “reflected his belief in the importance of the senses and empiricism in learning about nature (a doctrine associated with Newton and the philosopher John Locke)” will experience a sense of déjà vu on reading, in The World as We Know It, that the classification “reflects Buffon’s commitment to the epistemological stance of Newton and his philosophical underlaborer John Locke, who stressed the role of the senses in creating natural knowledge.” Later in the passage, we read that, “because of its stress on understanding the ways of life of animals in their environments, Buffon’s approach could almost be labeled (anachronistically) as ‘ecological.’” And again, “an anachronistic way of putting it would be to say that Buffon recommends an ecological mode of understanding.” Likewise, in The Intelligibility of Nature we read of Dalton that he was initially drawn to meteorology, and that: He did a bit of experimental work on these things, especially having to do with the water-holding capacity of gases, but his real interest lay in understanding what, at an underlying natural-philosophical level, was really going on physically.” Whereas, in The World as We Know It: He did experimental work on these things, especially concerning the water-holding capacity of gases — although not at a very refined level quantitatively — but he was continually trying to develop a theoretical conception of what was happening physically. The final full chapter of each book closes on the same resigned note. Intelligibility: These days, most serious work on the natural philosophical underpinnings and implications of quantum mechanics is performed not by physicists but by philosophers of science. Among scientific practitioners themselves, Bohr’s attempt to use instrumentality as sufficient grounds for a respectable science has met with a high degree of success. And again, in The World as We Know It: Bohr’s and Einstein’s concerns are now questions that are mostly discussed by philosophers of science rather than by physicists themselves. The marginalization of these sorts of questions amounts to the demise of natural philosophy, at least in physics, in the 20th century. Quantum mechanics “works,” and that’s good enough for most scientists who encounter it. Examples could be multiplied. When handling the same subject matter, some echoes are inevitable. Scholars should not feel that because they have written “Isaac Newton died in 1727” in one book, in the next they must describe him as perishing, expiring, or meeting his maker. But the repetitions of language and arguments (not to mention six reproduced images) threaded throughout The World as We Know It are more extensive than that. They should have been caught by Princeton University Press or its reviewers, and revised. Because the two books have so much in common, it is easy to see where they diverge. The World as We Know It is a less theoretical work than its predecessor. The sociology of knowledge that organized The Intelligibility of Nature has been reduced in scale and folded into readings and examples. The taut interplay between history and theory, which gave the earlier study so much interest, is there, but it is subtle. In the earlier book, the case studies demonstrated theoretical claims about the character and development of science. In the later work, each narrative of discovery is an end in itself. Insights emerge from the history, but they do not control the organization of the study. With the theory muted, it can be hard to understand the logic uniting Dear’s sprawling history of more than two centuries of scientific knowledge. The 16 brisk chapters cover an enormous amount of material. But the closer the volume edges to comprehensiveness, the more obvious the missing elements become. A chapter on “Institutions and Pedagogy,” describing the birth of the research university, illustrates the problem. Inserted roughly halfway through the book, the unnumbered chapter is designed as an “entr’acte,” in acknowledgement that it does not fit the study’s organization around scientific discoveries. Yet as Dear is well aware, no general history of the development of modern science can bracket its 19th-century institutionalization and professionalization. It was the 19th-century university, after all, that gave us the “scientist,” a term coined by the Cambridge philosopher William Whewell. Dear’s history of scientific discoveries implies a wider social and institutional history, but it remains largely subterranean, only occasionally extruded under the pressure of the narrative. It must be said that the balance is not all on the side of the earlier study. There are some advantages to the more historical, less theoretical organization of The World as We Know It. Dear’s accounts of paradigm shifts are remarkably lucid, no small accomplishment given that they span fields and centuries. He makes excellent use of the wealth of new scholarship on Darwin and his influences, to which he has himself contributed. It is satisfying to see puzzle pieces from Buffon’s natural history, Georges Cuvier’s animal taxonomy, Thomas Robert Malthus’s demography, and Charles Lyell’s geology recombined seamlessly in the Darwinian jigsaw. Likewise, Dear’s discussion of stellar nebulae, divided between chapters two and 15, shows vividly how Newton, Kant, Herschel, and Hubble reimagined insights and observations as they sought to discover whether the diffuse light that filtered through early telescopes was a glowing, gaseous substance or discrete but distant stars. Yet despite such pleasures, the book remains a more modest work than The Intelligibility of Nature. Dear has clearly not changed his views about the history of science. But in the two decades that have elapsed, the discipline and the world around it have changed, making it harder to write a sociologically and philosophically ambitious history of science for the general reader. That is a shame, because in the age of Silicon Valley and biotechnology, both the reciprocity and the tensions Dear identified between the epistemological and instrumental ambitions of science are more evident than ever. In recent years, some of the most exciting new books on the history of science in early modernity have focused precisely on this pressure point. Important studies such as Pamela H. Smith’s From Lived Experience to the Written Word (2022), James Poskett’s Horizons: The Global Origins of Modern Science (2022), and Vera Keller’s The Interlopers: Early Stuart Projects and the Undisciplining of Knowledge (2023) all shed new light on how early modern science negotiated the relationship between its instrumental and epistemological ambitions, or in Russell’s phrase, knowing and doing. There is every opportunity for a philosophically informed approach to draw new insights from this wealth of material. Dear, unfortunately, has not done so in The World as We Know It. But for future scholars of the history of science, his body of work over nearly four decades may provide just the model. Julianne Werlin is an associate professor of English at Duke University. Thanks for reading The Chronicle Review! Subscribe for free to receive new posts and support my work. Subscribe

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Oct 2 • 2:52 PM EDT • Science • chronicleofhighereducation.substack.com
Weekly Rundown: Duke University launches digital twin program; Welldoc unveils AI-powered care loop

Stay up to date on the latest in health tech, digital health and health AI news with this weekly brief. Read below for news from the week of Sept. 28 to Oct. 2. | The latest news from Yosi Health, Grindr, K Health, Welldoc, Duke University and more.

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Oct 2 • 12:00 PM EDT • Health • fiercehealthcare.com
Mary Klotman, Duke's Chief Academic Health Leader, will Complete Service in 2027

DURHAM, N.C. – After two decades in senior leadership at Duke and 10 years as dean of the Duke University School of Medicine, Mary E. Klotman, M.D., will complete service on June 30, 2027.

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Sep 29 • 3:00 PM EDT • Health • corporate.dukehealth.org
Fellow coastal scientists, advocates reflect on Joe Ramus' life

The respected professor, prolific researcher, former Duke University Marine Laboratory director, and environmental steward died Tuesday.

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Sep 28 • 12:00 AM EDT • Science • coastalreview.org
Procrastination study by Duke’s Dan Ariely retracted after sleuths find signs of data tampering

A psychology journal has retracted a seminal 2002 paper on deadlines and procrastination coauthored by behavioral scientist Dan Ariely of Duke University just days after a team of sleuths published…

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Sep 3 • 7:46 PM EDT • Science • retractionwatch.com
Mapping North Carolina’s Climate Health Risks

From the Blue Ridge Mountains to the Atlantic coast, North Carolina's geography does more than shape its landscape. It may also influence the health risks people face.At Duke University School of Medicine, researchers are combining climate data, geographic information, and real-world health records to better understand how environmental conditions affect health and why some communities face greater risks than others.

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Aug 26 • 8:00 AM EDT • Health • medschool.duke.edu
Wilmington announces business and economic development chief

The city of Wilmington announced on Thursday the hiring of Louis Starks as its new business and economic development manager. According to a news release, the role focuses on strengthening Wilmington's business ecosystem, supporting entrepreneurship and advancing strategic economic growth. "In this role, Starks will collaborate with residents, local businesses, community groups, educational institutions and regional partners to promote investment, workforce development, and innovation for businesses of all sizes," the release stated. "He will also help connect small businesses with City procurement opportunities, cultivate public-private partnerships, and lead initiatives that promote long-term economic vitality." Starks has more than 20 years of experience in economic development, urban planning, housing finance, workforce development and public policy, according to the release. Most recently, he served as manager of business development for Oakland County, Michigan, "where he led teams focused on business retention and expansion and financial services for one of the nation's most economically diverse regions. During his tenure, his teams supported billions of dollars in business investment initiatives while helping create thousands of jobs," the release stated. He holds a law degree and master's degree in urban and regional planning from the University of Iowa, as well as a bachelor's degree from Duke University. He is also a Certified Economic Development Professional. Starks is expected to begin his Wilmington position on July 27. “Louis has built his career around helping individuals, organizations and communities reach their full potential,” stated city manager Becky Hawke in the release. “Whether supporting entrepreneurs, managing complex redevelopment projects, or bringing together public and private partners, he has consistently focused on creating opportunity and delivering results. He understands that a strong economy creates opportunities for everyone. By supporting local businesses and fostering innovation, his work will help ensure the benefits of Wilmington’s growth are felt throughout the community, creating jobs, strengthening neighborhoods, and improving quality of life for residents.”

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Jul 23 • 2:03 PM EDT • Business • wilmingtonbiz.com
Sullivan to lead basic and preclinical science at Duke School of Medicine

Beth A. Sullivan, PhD, has been appointed vice dean for basic and preclinical science at Duke University School of Medicine, effective July 1, 2026.

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Jun 18 • 8:00 AM EDT • Science • medschool.duke.edu
How surviving leukemia changed Duke Health CEO's approach to patient care

A life-threatening leukemia diagnosis forced Dr. David Zaas to experience healthcare from the other side of the hospital bed. Now, the new Duke University Health System CEO says those lessons are guiding his approach to patient care and the future of Duke Health.

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Jun 17 • 11:41 AM EDT • Health • wral.com
Triggering the 'symphonic biology' of exercise for better health

Physician-scientist R. Sanders Williams of Duke University has worked across academia and industry exploring key questions in exercise medicine. The National Academy of Medicine member will deliver the season’s final Maury Strauss Distinguished Public Lecture at the Fralin Biomedical Research Institute at VTC on Thursday, June 4.

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Jun 2 • 3:10 PM EDT • Health • news.vt.edu
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Scientists “recharge” damaged nerves to ease chronic pain

For millions battling chronic nerve pain, even the softest touch can feel agonizing — but scientists may have uncovered a radically new way to stop it at the source. Researchers at Duke University found that damaged nerves can be revived by supplying them with healthy mitochondria, the tiny energy producers inside cells.

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May 23 • 8:00 PM EDT • Science • sciencedaily.com
Lindsell named vice dean for data science and AI

Christopher Lindsell, PhD, has been appointed vice dean for data science and AI for Duke University School of Medicine, effective April 1, 2026.

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Mar 31 • 8:00 AM EDT • Science • medschool.duke.edu
Most CFOs Lift US Economic Outlook Despite War in Iran, Tariffs

A survey by Duke University’s Business School and Fed banks find economic prospects are seen improving.

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Mar 29 • 4:00 PM EDT • Business • bloomberg.com
Duke University Health System names new CEO

Dr. David Zaas will return to Duke University Health System as its new CEO effective May 1. He brings experience from his recent leadership roles at Atrium Health Wake Forest Baptist and MUSC Health.

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Mar 25 • 3:22 PM EDT • Health • wral.com
New ranking highlights NIH’s impact on breakthrough science at Duke

Duke University School of Medicine received more than $514 million in research funding from the National Institutes of Health (NIH) in 2025, ranking 9th nationally among medical schools, according to new data from the Blue Ridge Institute for Medical Research

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Feb 24 • 7:00 AM EST • Science • medschool.duke.edu
Duke Health limits hospital visitors due to rise in respiratory illness cases locally and nationally

The Duke University Health System stated that hospitals and ambulatory surgery centers will temporarily limit patient visitations, effective Tuesday, Jan. 6. The release added that the restrictions will be reviewed if and when respiratory illness cases decline.

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Dec 31, 2025 • 6:55 AM EST • Health • wral.com
December 22, 2025: Rural Health Symposium Opens Registration, Announces Call for Abstracts

The Duke University School of Nursing will convene healthcare professionals, educators, researchers, community leaders, and policymakers for a 1-day symposium dedicated to reducing rural health disparities across North Carolina through […]

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Dec 22, 2025 • 4:00 AM EST • Health • rethinkingclinicaltrials.org
This AI finds simple rules where humans see only chaos

A new AI developed at Duke University can uncover simple, readable rules behind extremely complex systems. It studies how systems evolve over time and reduces thousands of variables into compact equations that still capture real behavior. The method works across physics, engineering, climate science, and biology. Researchers say it could help scientists understand systems where traditional equations are missing or too complicated to write down.

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Dec 21, 2025 • 7:00 PM EST • Science • sciencedaily.com
AI learns to build simple equations for complex systems

A research team at Duke University has developed a new AI framework that can uncover simple, understandable rules that govern some of the most complex dynamics found in nature and technology.

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Dec 17, 2025 • 6:02 AM EST • Technology • phys.org